LOCUS       reptomyces_RBGC_138666 16748 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_138666
VERSION     Streptomyces_RBGC_138666
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000381025.1
  ORGANISM  GCF_000381025.1
            .
FEATURES             Location/Qualifiers
     CDS             2..771
                     /protein_domains="PF07702"
                     /protein_domains="PF00392"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374018"
                     /pseudo=False
                     /translation="MADGSRTDAVHRAVRRADHARRVAGVLRRQIAGDGFPADRLPEER
                     LLAAEFGVSRNAVREALALLAQEGVVERRRGIGTLVRSRPYRHPLAQLAGLAEVLHHHG
                     GVVNTVREARRVRPPADVARKLRLEPGEEAVYLERLRRLDGSPLSLDSTYLLTEVGDPL
                     LALEPAALEHHDVFHLIETVAGAPLGRAEVSVQAVAADPATREVLGMPESGAVLAVERL
                     ARLADGRPADVELLHLRGDRLTLHAELDRPSAGA*"
     CDS             817..2318
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374019"
                     /pseudo=False
                     /translation="VRHALHGTAEPSRRSSGRRGLTAAMCLSVTLVVGMVSAVNLAIPE
                     ISADPVRPSATAVVWVVDGYLLTFACLLLPAGALADRLGRKGVLLVGLGLFTLGNLVCA
                     AAPHVGVLIAGRALSGAGAAAVLPTTLALLVHERTGAERSRAVAVWASMTGLAAVLGNV
                     GGGAALELGSWRALFLAVTPLACGALLLVAALAPAVPRTPRPVSWPGAVLLTGAVAALL
                     YAVVSGPQQGWGSAPVLCAFAAAAFLGPAWAGSELRARHPLLDPALLTSSRVLAAAAGM
                     ALLFTGMFGLFLLNGQYLQYVQGTGPLGAGVRLLPMAAALLAGPRCGLLLRRVLGDGAT
                     AAGGMLVLAAGLAVVSRIDPHTPYALYACGAVLTALGCGIATPVFSETMVSALPGERAG
                     AGSGLQSLTRELGSAFGIAVTGSLVTAGFTARLPARLTGEPVPTTVPAARARATEAGAG
                     EALDPGILAAFTGAVHTATLVLAAGIALAALPVGRGVRHREG*"
     CDS             complement(2353..3434)
                     /protein_domains="PF01510"
                     /protein_domains="PF01471"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374020"
                     /pseudo=False
                     /translation="MASHSPLGRRSLLAGGLTVSAVGALGLGAASAGAAPQRSQPGRVA
                     ADSEEPRIYDTQEWGAREPDGQIVVLDRVPTYIVVHHTAEPGNSEDYSLEHAMQICRDI
                     QDFHMDGQGWGDTGQQFTNSRGGYALEGRHRSLEVVRGGTQHVQGANVADRNSEVIGIE
                     NEGLYSEVDVPEALWDSLVSLVAWIATQYDRPVENIMGHRDFNSTECPGEVLYGRLQEL
                     REAVAGAMGTRAPAAPLAWPLLKPGSSGPRVRAAQHLLRAAGFPSVRADGVFGPETKRA
                     VAKLADSAGVKPHTCSALHHSKVDETGFLGSDIWPLLTPRVTAASGSEVSDAVTQLRRA
                     GGELRTSGVLGKDDWKRLLA*"
     CDS             complement(3549..4063)
                     /protein_domains="PF01551"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374021"
                     /pseudo=False
                     /translation="MSRKRRGAVALAASGVLSVAAAAPALAASSDSPRTQGSSASYAAS
                     CPVAAEISQGYHEGHDGVDLAAPLGTPIHAAGPGEVTESGPATGYGQWVRIRHDDGSVT
                     EYGHMYERFVAVGDTVDGGQRIASVGSEGESTGPHLHFEVHHDGGYGFGDDPVAYLAER
                     GVPLPCTP*"
     CDS             complement(5247..5935)
                     /protein_domains="PF07729"
                     /protein_domains="PF00392"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374022"
                     /pseudo=False
                     /translation="VADGQVTGQEGRRIVGAGIRARLSAGEMAPGQRLVEQELSETFGT
                     TRSAVREALQDLAAEGLVELIPRRGARVRVISVEEAVQITECRAALEGLCARRAAASAG
                     DADRAELRDIGEQMSRAVTEGDLDAYSALNRRLHDTIARASGQEVAENLLDRLNGQTVR
                     FQFRLALRPGRPAQSLPQHLAIIEAVVTGDGAAAEAAARAHLDSVIAELAATPERPEPV
                     GSEVAVP*"
     CDS             5922..6118
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MAVRHPYRSSARTQLAAPCTGLAGESTGPDLVDDNGKFFINHIVN
                     NLVDGYVPCVTSSEGSHAPP"
     CDS             6116..7332
                     /protein_domains="PF04303"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374023"
                     /pseudo=False
                     /translation="MTPPTPRPADAALRHGTRRHGQQTAVPCWFMRGGTSRGPFFRAGD
                     LPAETAARDAVLLAALGSPDPRQVDGLGGAHPLTSKAGIVGPSQLPDVDLEFRFAQLQP
                     ESDVVDTTSNCGNMLAAVVPFALEAGLLAAHGETTTARVHTLNTGLTADITVRTPLGPD
                     GRYVAYDGEARIDGVPGTAAPVSVGFLDTEGSVCSALLPTGRVRDRVEVEGLGPVDVTC
                     IDNGMPLVLVPAAALGRTGYEPAAELTADVALRTRLERLRLACGRRMGLGDVAGLNYPK
                     MTLTAPPAERGAVATRSFIPHVCHASIGVLAAVTVATACVLDGTVAHEAATLPAVGPQE
                     GGGFATTVSVEHPSGEFSVALGLDADLRTVTRSALLRTARLIMAGEVMVPAAAHPVPHE
                     HEEDQR*"
     CDS             7330..8354
                     /protein_domains="PF04909"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374024"
                     /pseudo=False
                     /translation="MIIDCHGHYTTAPPALAQWREQQIAALGGPAAAPDPAGPHLGDDE
                     IRESIECNQLRLMDERGIDLTVFSPRASFMAHHVGDFATSQKWAARCNDLCHRVSALYP
                     ERFAPAAMLPQSPGVDPATCVPELTRAVEELGAVAVNLNPDPSGGHWSAPPLTDRAWYP
                     LYEKLVELDVPAMVHVSTSVNPAFHTTGGHYLNADTTAFMQLLQGDLFADFPALRLIVP
                     HGGGAVPYHWGRFRGLAAALGRPTLEEHLLGNVFFDTCVYHQPGIDLLLGVVPARNVLF
                     ASEMIGAVRGIDPRTGFAFDDTRRYVESAGLSPEDLAAVEERNARTVYPRLDALLRRQG
                     R*"
     CDS             8376..9058
                     /protein_domains="PF03737"
                     /protein_domains="TIGR02798"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374025"
                     /pseudo=False
                     /translation="VFALGVVHRTVNRPPTADVEALSEFGVSTLHEAMGRVGLMRPYLR
                     PVYRGARLCGPAVTVLLQPGDNWMLHVAAEQVRPGDVVVAACTTESEDGFFGELLATSL
                     RAQGARGLVIDGGCRDVAELEAMDFPVFSRAVNAKGTVKATLGSVNVPVVCANAPVRPG
                     DVVAADADGVVVVPAERAAEVAEAAARREANEEGKRQRFAAGELGLDMYAMREPLREAG
                     LRYLD*"
     CDS             9121..10040
                     /protein_domains="PF04909"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374026"
                     /pseudo=False
                     /translation="MSTRFRKTPGWLDWHPDPAKPTYRLPSGAVDAHCHVFGPGDEFPY
                     AAARKYTPCDASKEQLFALRDHLGVARNVVVQATCHGADNTAMLDAVRSAGGRARGVAT
                     VRPDVTDAELCRLDAAGVRGVRFNFLKRLVGPAPQDDLARIAARIAPLGWHVVLYFEAA
                     DLPELEGFFAALPTPLVIDHMGRPNVREPAAGPQFTRFLRFAERNDVWVKVSCPERLSL
                     TGPAALHGERSAYADVVPFARTVVEEFPDRVLWGTDWPHPNLTDHMPDDGLLVDHIPHV
                     ATTEQQRHKLLVDNPVRLYWPDETA*"
     CDS             10139..11505
                     /protein_domains="PF00083"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374027"
                     /pseudo=False
                     /translation="MAHPNAAHRLDRLPISRFHKVTLVAVAFAYFFEFADINSFAVTAP
                     RLITLWDVTVDQVAYVTSLSFVGMFIGSVVASRIADRLGRKKALTLTTVFFGTFSLLSS
                     FAWDILSLGVLRVLTSAGLSAMTVVAVVYVSELYPSAVRGKYQAYAIVIGICGTPVTSL
                     IASLVVPLADWTWRLVFLWGALGILFLAFTRRLKESPRWYESKGEYDKAEATLREIEAQ
                     VEAEKGPLPEPLPPVDEAPQTKAPLKLLLQRKYLVPTLVLTVLWVTQTIGFFGYSSWAP
                     TLLAKEGFSVEKSIFYIALTTVGAPLGSYVASLVTDRFERKWCLVVFGLAIAVCGLLYG
                     LTFNPVFIIVFGFAVNMLERGYTALAYAYSPELFDTRGRSLGTGISYGLGRLSNAAGPL
                     VIAALYNSTGYQSVFFFIAGTWVVGAVVLALFGASTRRARLASARGPAEETEPSAV*"
     CDS             complement(11385..12127)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374028"
                     /pseudo=False
                     /translation="VVVRRRAVHGTGVRAPPRPSASGTPPRAANCVRASGEIPPGAERR
                     VDRRAGHGRVARGRLRLRCLHRRPPPTVPSPASRTSASCWPNKRSSSGSSPSSTRPGRS
                     ASRTNCTALPVLSATAGTRADGASSPQGGCPDAAPRAEAAAGRGGRSRSPSHPADGRGS
                     PCARRASLAGSGSRGSPSTGRLPNGPCEAARWHAVRQPPPDDVHVTPPRARSPRPVPVP
                     RRGGRGGCWLRRGRARRRRRPRCPR*"
     CDS             complement(12145..12878)
                     /protein_domains="PF03575"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374029"
                     /pseudo=False
                     /translation="VKLLLLSNSSAPGRGYLDHAREVVAEHLGGVRELLFVPYALADHD
                     AYTAKVAAFMGELGVRVRGLHGSGDPRAEVAAAEAVFVGGGNSFRLLRALQGHGLVPEL
                     ARRVQEDGVPYMGSSAGTNMACPTLRTTNDMPIVQPTSFGTLGLVPFQINPHYLDPQPG
                     SAHMGETREERLTQFLEENDVPVLGLREGTWLQRRDGVLELGGTSAGARLFSAGAEPVE
                     YAPGADLSSLLAVAPRFDHRLG*"
     CDS             complement(12902..13728)
                     /protein_domains="PF09339"
                     /protein_domains="PF01614"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374030"
                     /pseudo=False
                     /translation="VDTDRVRRVTTDRGAPLKTADRTLQVLLAFTHDRDEWGVTDLAAE
                     FGWDKSVTQRLLAALAHRGFLVSDAVTRRYRLGPAVWHMATAWERHGGMAGLVRPALRE
                     LAAESGVTALFAVPDGAHLRCVDSADGTLGPLRTYRLAEELYPGHAGATSRAYFGMLAP
                     GARAAALYGRPMARFSERTVTDPAQLEELMCRVPADGYAYSEGEYDPATAGLAVPVVVR
                     SQPVGSLTLVGPHRQLADDREELLIPLRSAAEGLGELLTPRRVRGRTPRTSRN*"
     CDS             13822..14984
                     /protein_domains="PF06675"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374031"
                     /pseudo=False
                     /translation="MPGATSKGATAPAARSRITPAATTLPLARPPPVAHQRGGPGIAPK
                     ASPSESRPHHPKEPTVLKHVLDVLELLDRPQADGHSLDAHLRDVLHRAAQQAGRTAEAD
                     RVEISVTRIEGAQGGTDFVKAVVPGRDGARAGGSAPTLGVLGRLGGVGARPERTGLVSD
                     ADGAVAALAATSKLLDMYGRGDVLDGDVILSTHVCPDAPTRPHDPVPFMDSPVSILDCN
                     RQEIDGAMDAVVSIDTTKGNRLLNHRGLALSPTAKEGWILRVSDDLLGILETVTGEDAH
                     VLPITTQDITPYGNGVHHINSIMQPCVATSAPVVGLALTTGPAVAGCATGASHETDIAA
                     AGRFAVEAAKEYGRGAARFHDAEEFARLVDLYGPMTRLQSTAGATED*"
     CDS             15088..16748
                     /protein_domains="PF03169"
                     /protein_domains="PF03169"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7374032"
                     /pseudo=False
                     /translation="MSTSPAPAPEARRAHPRALEPVTLVVTVLLSVLGAVIGLVLITTL
                     GIAPNTSVIGALIAMLIGRLSFATLSRMRDPHRQNLVQSAISGSTFAAANSLVTPIAVP
                     FLLGEPGLVWPMLGGAVIGLAVDSWVLYRVFDSRLLPATAAWPAGIAAAETIKAGDEGG
                     RKAGMLGVSAVVGFLGSLFKLPMSAAGVAFLGNIWALLMFGVGLLVAQYAPTLLDTDLS
                     ANHVPHGVMIGAGLVALVQAVRLMRERDGGSKDQQPAREAEDAFDPQTRTVDARRLRRG
                     LLEGLALFLVGALFVALTGGILADMSGLGLVGWVLLAGVAALVHQLIVGLAAMHSGWFP
                     AFAVTLIFLILGLVLGIPMVPLALLVGYAASTGPAFADVGFDFKAGWLLRKDAVPWHPY
                     EMAGRRQQYVAQLVGFAVAILVVVVAWKPFFEDGRVPPVAQVYVDTLKAGLSDTHALTM
                     MALWAIPGALVQLLGGSSRQMGVLLATGLLVATPQAGWLVLAALAVRFGYARRAKRRAD
                     SGDGQQAAADNDLALVGAGLVAGSSLNDVSQIYKAV*"
ORIGIN
        1 atggcggacg ggagccgaac cgacgcagta caccgcgccg tgcgacgggc cgaccacgcg
       61 cgcagggtcg cgggcgtact gcgccgccag atcgccggcg acggattccc cgcggaccgc
      121 ctcccggagg agcggctcct cgcagcggaa ttcggcgtct cccgcaacgc ggtccgcgag
      181 gcgctcgccc tcctcgcgca ggaaggcgtc gtggagcgcc gccgcggcat cggcaccctc
      241 gtgcgcagcc gcccctaccg gcatccgctc gcacagctcg ccggcctcgc cgaggtgctc
      301 caccaccacg gcggcgtcgt caacaccgtc cgcgaggcgc gacgcgtccg gccccccgcc
      361 gacgtcgcgc ggaagctgcg gttggagccg ggggaggaag ccgtctacct ggagcggctc
      421 cgccgcctcg acggctcgcc cctctccctc gactcgacct acctcctcac cgaggtcggt
      481 gacccgctcc tcgccctgga gcccgccgcg ctcgaacacc acgacgtctt ccacctcatc
      541 gagaccgtgg cgggtgcgcc gctcggccgc gccgaggtct ccgtccaggc ggtcgccgcc
      601 gacccggcca cccgtgaggt cctcggcatg cccgagagcg gcgccgtcct cgccgtcgag
      661 cgcctcgccc gcctcgccga cggtcggccc gccgacgtcg agctcctcca cctgcgcggc
      721 gaccgcctca ccctccatgc cgaactcgac cgcccgtccg ccggcgcctg actgccgctc
      781 ccgcccgaca cccgccgcac accaggaggt aagcggtgcg ccacgcactg cacggaaccg
      841 ccgagccgag ccgtcgttcc tcgggcaggc gcggactcac cgccgcgatg tgcctcagcg
      901 tcaccctcgt cgtcggcatg gtctccgccg tcaacctcgc catccccgag atctccgccg
      961 accccgtgcg gccgtccgcc accgccgtgg tgtgggtcgt cgacggatac ctcctcacct
     1021 tcgcctgcct tctgctgccc gccggggcgc tcgccgacag gctcgggcgc aagggcgtac
     1081 tcctcgtggg gctcggtctg ttcacgctcg ggaacctcgt ctgcgcggcg gcgccgcacg
     1141 tcggtgtgct catcgccggg cgtgccctga gcggcgcggg ggcggccgcc gtgctgccga
     1201 ccacgctcgc gctcctcgtc cacgagagga cgggcgccga gcgctcccgc gccgtcgccg
     1261 tctgggcgtc gatgacgggg ctcgccgccg tcctcggcaa cgtgggaggc ggcgccgcgc
     1321 tggaactcgg ctcctggcgg gcgctgttcc tcgccgtcac gccgctcgcc tgcggcgcgc
     1381 tgctcctcgt cgccgcgctg gcgcccgccg tgccccgcac cccgcggccc gtctcctggc
     1441 ccggagccgt gctgctcacc ggcgccgtcg ccgcgctgct ctacgccgtc gtctccggac
     1501 cgcagcaggg gtggggcagc gcacccgtcc tctgcgcctt cgccgctgcc gcgttcctcg
     1561 ggccggcgtg ggcgggcagc gaactccgcg cccggcaccc gctgttggac ccggccctcc
     1621 tgacgagctc ccgcgtcctc gccgcggccg ccgggatggc gctcctcttc accgggatgt
     1681 tcgggctgtt cctcctcaac gggcagtacc tccagtacgt acagggcacg gggccgctcg
     1741 gcgcgggggt ccgcctgctg ccgatggccg ctgcgctcct tgcggggccg cgctgcggac
     1801 tgctgctgcg ccgtgtcctc ggcgacgggg cgacagccgc gggcggcatg ctcgtgctcg
     1861 ccgcggggct cgccgtcgtc tcgcggatcg acccgcacac gccgtacgcc ctctacgcct
     1921 gcggtgccgt gctcaccgcg ctgggctgcg gcatcgccac gcccgtcttc tccgaaacca
     1981 tggtctccgc gctgccgggc gagcgcgccg gggccgggtc cggactccag tcgctcaccc
     2041 gggagttggg gagcgccttc ggcatcgcgg tcaccggcag cctcgtcacg gcgggcttca
     2101 ccgcgcggct cccggctcgg ctcaccggtg aaccggtccc caccaccgtg cccgccgcca
     2161 gggcccgcgc gacggaggcc ggtgcgggcg aggcgctgga ccccggcatc ctcgccgcct
     2221 tcaccggtgc cgtgcacacg gcgaccctcg tcctcgccgc cggtatcgcg ctcgccgcgc
     2281 tgcccgtggg gcgcggggtg cggcaccggg aggggtgagg gggccggcgc ggggccggcc
     2341 cccggtgggt gtcaggcgag caggcgcttc cagtcgtcct tgcccagcac gccgctggtc
     2401 ctcaactcac cgccggcgcg gcggagttgc gtcaccgcgt cggacacctc gctgccggag
     2461 gcggccgtca cgcgcggcgt cagcagcggc cagatgtcgg agccgaggaa gccggtctcg
     2521 tccaccttcg agtggtgcag ggccgagcag gtgtgcggct tcacgcccgc ggagtcggcg
     2581 agcttcgcca cggcgcgctt cgtttcgggg ccgaagacgc cgtcggcgcg taccgagggg
     2641 aagccggcgg cgcgcagcag gtgctgcgcc gcgcgcaccc ggggccccga gctccccggc
     2701 ttcagcagcg gccaggcgag cggtgcggcc ggcgcccgcg tgcccatcgc gccggcgacc
     2761 gcctcgcgca gctcctggag gcgtccgtag aggacctcgc ccgggcactc ggtggagttg
     2821 aagtcccggt ggcccatgat gttctcgacc gggcggtcgt actgggtggc gatccaggcg
     2881 accagcgaga cgagcgagtc ccacagcgct tcggggacgt cgacctcgga gtagaggccc
     2941 tcgttctcga tgccgatgac ctcgctgttg cggtcggcga cgttggcgcc ctgcacgtgc
     3001 tgcgtcccgc cgcgtaccac ctcgaggctg cggtggcgcc cttccagcgc gtacccgccg
     3061 cggctgttgg tgaactgctg cccggtgtcg ccccagccct gcccgtccat gtggaagtcc
     3121 tggatgtcgc ggcagatctg catcgcgtgt tcgagcgagt agtcctcgct gttgcccggc
     3181 tccgccgtgt ggtgcaccac gatgtaggtg gggacccggt cgaggacgac gatctgcccg
     3241 tccggctccc gggctcccca ctcctgggtg tcgtagattc tcggctcctc cgagtcggcg
     3301 gcgacgcggc ccggctgcga tctctgtggc gcggcgcccg cggaggcggc gccgagcccg
     3361 agggctccga cggccgacac ggtgaggccg cccgcgagca gggagcggcg tcctaggggg
     3421 gagtggcttg ccatgacgat ctccttttgc ggtgtggggg gttggagagt gcgcggctcc
     3481 tccggtcggc tccgtggggg tgccggccgg ggagcaggga gcgtcgtgtg cgggtgcgcg
     3541 gcggcggtta cggcgtgcag ggcagcggga ctccgcgctc cgccaggtag gccaccgggt
     3601 cgtcgccgaa gccgtagcca ccgtcgtggt gtacctcgaa gtgcaggtgc ggaccagtcg
     3661 actcgccctc gctgccgacg gaggcgatcc gctgcccgcc gtcgacggtg tcgccgacgg
     3721 cgacgaacct ctcgtacatg tgtccgtact cggtgaccga gccgtcgtcg tgccggatgc
     3781 gcacccactg cccgtacccg gtggcagggc cggactcggt gacctcgccc ggccctgccg
     3841 cgtggatggg cgtgccgagg ggtgcggcga ggtcgacccc gtcgtgcccc tcgtggtaac
     3901 cctggctgat ctcggctgct acggggcacg acgccgcgta ggaggccgaa ctcccttgcg
     3961 tccgggggga gtcggagctt gcggcaaggg cgggcgccgc agcggcgacg ctcagtaccc
     4021 cactcgccgc aagggcgacg gcacctctgc gcttgcggga cattcttctc ccttcgtcgg
     4081 ttcgggtccc cggcatccac ccagcagtct tgctcatgta cgcgacaatg tctccctctt
     4141 gtgcgggatt agctacgcgc ggagaacggc gccgaactcg gccaacgccg cccgctcgcc
     4201 gggccgttga cgccccaccc gccgcgacct gcggggtgcc gtcgaccgcc cggggggccg
     4261 tcccggtgcg ccttcgtagg ccggcttacc gcgggctcgg aacaagaagg gcgcgcaacc
     4321 gtaaggggac ttggcaacgt cagccggagg ccggtgcaca cgagtgggct ggtagcacgt
     4381 gtccgaagtc ccgtcccctc gcctgcgtct cctccgggag agttacggcg accccgtggg
     4441 cgtcgaggag gcgcggtcca ggcactgggg ccgcctcgtc gccgacgccg agcatcggga
     4501 atgcgtcacc ctggggaggg cgagcgcctc gccgccaccg ctccccggga ccgcaggacg
     4561 cgtccccctc agcgcggccc gcgccaagct cggcgacctc gtccgccgcg ccaccgcact
     4621 ctccgacccg gtggcgcaca gcctcactcg tcacggtgtc gccgtcgctg tgctcctcga
     4681 cgtcgcccgc ctccagtccc ggcacccgac gcagcaccgg agccggcccc cgcgcccgcc
     4741 gcgctcggtg acgtcacggc gtccacccag ccgtacggcc tcgtcgcccg gatcgagcag
     4801 atcgtcgacc tgggctcgca gtgggggagg tacgagtacg tgacgtccgt cggcttctcg
     4861 gcctgaccgc acggcccccc gacaccggac gctccgggcg ggccgcccgg ttcgcgtgcg
     4921 taagggtctg ctgcgacgcc aggtatccgg gtaacgaact gaccggctcc tggccgtact
     4981 tcacgacgag cgcgggtccc tacatcctgc tcgcccggtt cgagtcgagc ccgaaccccg
     5041 gcgaagcgca gtgaacccgc cgctcaaagg cacgcgctgc tgggcgagtt ccgacctccc
     5101 tgccgtttcg accggcgtcg cccagcagcg ccggcacgcc gtactcgcaa ccatccgcca
     5161 ccggcgctcc gttcatgcga gcgcagcgcg cagccgcccc cccgaacgag cctccagcgt
     5221 cggctcgtcg tgctcgcctc ctggcctagg gcaccgcaac ctcgctgcca acaggctccg
     5281 ggcgctcagg agttgcggcg agctcggcga tgacgctgtc gaggtgggcc cgtgccgctg
     5341 cctccgcggc ggcgccgtcg cccgtgacca ccgcctcgat gatcgccagg tgctggggga
     5401 gcgactgcgc ggggcgcccg ggacggaggg cgaggcggaa ctggaagcgg acggtctggc
     5461 cgttgaggcg gtctaggagg ttttccgcca cctcctggcc gcttgcgcgg gcaatggtgt
     5521 cgtggaggcg ccggttgagc gccgagtagg cgtcgaggtc gccttcggtg acggcgcggc
     5581 tcatctgctc gccgatgtcg cggagttcgg cgcggtccgc atcgcccgcc gaggctgccg
     5641 cccgccgggc gcacaggccc tccagggcgg cccggcactc ggtgatctgc actgcctcct
     5701 cgacggagat cacccggacc cgcgcgccgc gcctgggtat cagctccacc aggccctcgg
     5761 cggcgaggtc ctggagcgct tcgcgtaccg cgctgcgggt ggtgccgaac gtttccgaca
     5821 gctcctgctc gacgaggcgt tggcctggtg ccatctcgcc ggcggagagc ctcgcgcgga
     5881 tgccggcccc gacgatgcgg cgcccttcct gaccggtgac ctggccgtcc gccacccgta
     5941 ccgctcctct gctcgcactc aactcgccgc cccctgcacg gggctggccg gggagtctac
     6001 cggccccgac cttgttgacg acaatggaaa gtttttcatc aaccatattg tcaacaatct
     6061 cgtcgacggt tacgttccct gcgtcacctc ctcggaaggg agccacgcac caccatgacg
     6121 ccgcccaccc ctcggcccgc cgacgccgca ctccggcacg gcacccgccg ccacggtcaa
     6181 cagaccgcgg tgccctgctg gttcatgcgc ggcggcacct cgcgcggccc gttcttccgc
     6241 gccggcgacc tccccgccga gacggccgcg agggacgccg tcctcctcgc cgcgctcggc
     6301 tcccccgacc cccgccaggt ggacggcctc ggcggcgccc acccgctcac cagcaaggcc
     6361 ggcatcgtcg ggccgagcca actccccgac gtcgacctgg agttccggtt cgcccaactc
     6421 cagcccgaga gcgacgtcgt cgacaccacc tccaactgcg gcaacatgct cgccgccgtc
     6481 gtccccttcg ccctcgaagc gggactcctc gcggcacacg gagagaccac cacggcgcga
     6541 gtgcacaccc tcaacaccgg cctcaccgca gacatcacgg tgcgcacccc actcggaccc
     6601 gacggccgat acgtcgccta cgacggcgag gcgcgcatcg acggcgtccc cgggaccgcg
     6661 gcgcccgtga gcgtcggctt cctcgacacg gagggctccg tctgttccgc gctgctgccc
     6721 accgggcgcg tgcgggaccg cgtcgaggtc gaggggctcg gccccgtcga cgtcacctgc
     6781 atcgacaacg ggatgccgct cgtcctcgtc cccgcggcgg cgctcggccg caccgggtac
     6841 gagccggccg cggaactcac cgcggacgtc gcactgcgca cgcgcctgga gaggttgcgg
     6901 ctggcgtgcg ggcggcgcat gggcctcggc gacgtggccg gcctcaacta ccccaagatg
     6961 acgctgacgg cgccgcccgc cgagcgcgga gccgtcgcca cccggagctt catcccgcac
     7021 gtctgccacg cctccatcgg cgtcctcgca gccgtcacgg tcgccacagc ctgtgtcctc
     7081 gacgggaccg tcgcgcacga ggcggcgacg ctccccgcgg tcgggccgca ggagggaggc
     7141 ggcttcgcca cgaccgtctc cgtcgagcac ccctcggggg agttcagcgt cgcgctcgga
     7201 ctcgacgcgg atctccgcac cgtcacgcgc tccgcgctgc tgcgtaccgc ccggctgatc
     7261 atggccggcg aggtcatggt tcccgcggcc gcgcaccccg tcccgcacga acacgaggag
     7321 gaccagcgat gatcatcgac tgccacggcc actacaccac ggcgccgccg gcgctggcgc
     7381 agtggcggga gcagcagatc gccgccctcg gaggacccgc cgcggcgccg gaccccgcgg
     7441 ggccgcacct cggtgacgac gagatacgcg aaagcatcga gtgcaaccaa ctccgcctca
     7501 tggacgagcg cggcatcgac ctcaccgtct tctcgccgcg cgcctccttc atggcgcacc
     7561 acgtcggcga cttcgccacc tcgcagaagt gggccgcccg ctgcaacgac ctctgccacc
     7621 gggtgagcgc cctctacccc gagcggttcg cccccgcggc catgctcccg cagtcgcccg
     7681 gcgtcgaccc ggccacctgc gtccccgaac tcacccgcgc cgtcgaggag ttgggcgccg
     7741 tcgcggtcaa cctcaacccc gacccgtccg gcggccactg gagcgcaccc ccgctcaccg
     7801 accgtgcctg gtacccgctc tacgagaagc tcgtcgagct cgacgtgccg gccatggtcc
     7861 acgtgagcac cagcgtcaac ccggccttcc acaccacggg cggccactac ctcaacgccg
     7921 acaccacggc gttcatgcag ctcctccagg gcgacctgtt cgccgacttc cccgcactgc
     7981 gcctgatcgt cccgcacggc ggcggcgccg tcccctacca ctggggccgc ttccgcggcc
     8041 tcgctgcggc cctcgggcgc ccgacgctcg aggaacacct gctcggcaac gtcttcttcg
     8101 acacctgcgt ctaccaccag cccggcatcg acctgctcct cggagtcgtg ccggcccgga
     8161 acgtgctctt cgcctcggag atgatcggcg ccgtccgcgg catcgacccc cgcaccgggt
     8221 tcgccttcga cgacacccgc cgctacgtcg agtcggcggg gctctccccc gaggacctcg
     8281 ccgccgtcga ggagcgcaac gcccgcaccg tctacccgcg cctcgacgcc ctgctgcggc
     8341 gtcagggccg ctgacctacg cacaaggagc cgtcgtgttc gcactcggtg tcgtacaccg
     8401 caccgtcaac cgcccgccga ccgccgacgt cgaagcgctc tcggagttcg gggtgagcac
     8461 cctccacgag gcgatgggcc gcgtcggact gatgcgcccc tacctccgcc cggtctaccg
     8521 cggggcccga ctctgcggtc ccgccgtcac ggtgcttctc caaccgggcg acaactggat
     8581 gctgcacgtc gcggccgagc aggtacggcc gggggacgtg gtcgtcgccg cctgcacgac
     8641 cgagagcgag gacgggttct tcggcgaact cctcgccacc tcgctgcgcg cccagggcgc
     8701 acgtggcctc gtcatcgacg gcggctgccg cgacgtggcc gagctggagg cgatggactt
     8761 ccccgtcttc tcccgggccg tcaacgccaa gggcacggtc aaggccacgc tcggctccgt
     8821 caacgtgccc gtggtctgcg ccaacgcgcc cgtacgcccc ggcgacgtcg tcgccgccga
     8881 cgcggacggc gtggtcgtcg tccccgccga gcgtgccgcc gaggtcgccg aggcggcggc
     8941 gcgccgcgag gccaacgagg aggggaagcg acagcgtttc gccgccgggg agctcggcct
     9001 cgacatgtac gccatgcgcg agccgctccg cgaagccggc ctccgctacc tcgactgacc
     9061 ccgtccgcac cacgtaccgc cggtcgcccg cccctccgcg tgccggccga ggaggagaga
     9121 tgagtacgcg cttccgcaag accccgggct ggctcgactg gcacccggac ccggcgaagc
     9181 cgacgtaccg gctgccgtcg ggagccgtgg acgcgcactg ccacgtcttc ggccccggcg
     9241 acgagttccc ctacgccgcc gcacgcaagt acacgccctg cgacgcgagc aaggagcaac
     9301 tcttcgcgct ccgcgaccac ttgggcgtcg cgcggaacgt cgtcgtccag gccacctgcc
     9361 acggcgccga caacaccgcc atgctcgacg ccgtccgctc ggcaggcggc cgcgcccgcg
     9421 gcgtcgccac cgtgcgtccc gacgtcaccg acgccgagct gtgccgcctc gacgcggccg
     9481 gggtgcgcgg cgtccgcttc aacttcctca agcggctcgt cggtcccgcg ccgcaggacg
     9541 acctcgcccg tatcgcggcg aggatcgcac cgctcgggtg gcacgtggtg ctctacttcg
     9601 aggccgccga cctccccgaa ctggaagggt tcttcgccgc cctgcccact ccgctcgtca
     9661 tcgaccacat gggccgcccc aacgtacggg agcccgccgc ggggccgcag ttcacgcggt
     9721 tcctgcggtt cgccgagcgc aacgacgtgt gggtgaaggt gagttgcccc gagcggctca
     9781 gcctcaccgg gcccgccgcg ctccacggcg agcgcagcgc ctacgccgac gtcgtgccct
     9841 tcgcgcgcac ggtcgtcgag gagttccccg accgcgtgtt gtggggcacc gactggcccc
     9901 accccaacct caccgaccac atgcccgacg acgggctgct cgtcgaccac atccctcacg
     9961 tggccaccac cgagcagcag cgccacaagc tcctcgtcga caaccccgtg cggctctact
    10021 ggccggacga gacggcctga ccggccccgt cccgccgccg cccgtcccac ctgccgcgac
    10081 ggcggtcgcc cgcgcctgcg ccgagaccgc cgccctcccc tcaccgaagg cgttgccatg
    10141 gcacatccga acgcggcgca ccggctcgac cggttgccga tatcccgctt ccacaaagtg
    10201 acgctcgtcg ccgtcgcctt cgcgtacttc ttcgagttcg cggacatcaa cagcttcgcc
    10261 gtcaccgccc cgcgcctgat caccctctgg gacgtcacgg tcgaccaggt cgcctacgtc
    10321 acctcgctct ccttcgtcgg catgttcatc ggctcggtcg tcgccagccg catcgccgac
    10381 cggctggggc ggaagaaggc actcaccctc acgacggtct tcttcggcac cttctcgctc
    10441 ctctcctcct tcgcctggga catcctgtcg ctcggtgtcc tccgcgtcct cacctcggcg
    10501 gggctctccg cgatgaccgt cgtcgccgtg gtctacgtga gcgagctcta cccctccgcc
    10561 gtccgcggca agtaccaggc gtacgccatc gtcatcggca tctgcgggac ccctgtcacc
    10621 agcctcatcg ccagtctcgt cgtgccgctc gccgactgga cctggcggtt ggtcttcctc
    10681 tggggcgccc tcggcatcct cttcctcgcc ttcacccggc gcctcaagga gtcgccgcgt
    10741 tggtacgaga gcaagggcga gtacgacaag gccgaggcga ccctccgcga gatcgaggca
    10801 caggtcgagg cggagaaggg gccgctgccc gagccgctcc cgcccgtcga cgaggccccg
    10861 cagaccaagg ccccgctcaa gctgctcctc cagcgcaagt acctcgtgcc cacgctggtg
    10921 ctgaccgtcc tgtgggtcac ccagacgatc ggcttcttcg ggtactcgag ctgggcgccg
    10981 acgctgctcg ccaaggaggg cttcagcgtc gagaagtcga tcttctacat cgcgctcacc
    11041 acggtcggcg caccgctcgg ctcctacgtc gcgtcgctcg tcaccgaccg cttcgagcgc
    11101 aagtggtgcc tcgtagtctt cggcctcgcc atcgccgtct gcgggctgct gtacgggctg
    11161 acgttcaacc ccgtcttcat catcgtcttc ggcttcgccg tcaacatgct ggagcgcggc
    11221 tacaccgccc tcgcctacgc gtactcgccc gagctcttcg acaccagggg ccgctccctc
    11281 ggcaccggca tctcctacgg cctcggccgc ctctccaacg ccgcgggccc gctcgtcatc
    11341 gcggcgctct acaacagcac gggataccag agcgtcttct tcttcatcgc gggcacctgg
    11401 gtcgtcggcg ccgtcgtgct cgccctcttc ggagccagca cccgccgcgc ccgcctcgcc
    11461 tcggcacggg gaccggccga ggagaccgag ccctcggcgg tgtgacgtgc acatcgtccg
    11521 gcggcggctg ccggacggcg tgccaacgcg cggcttcgca cggcccgttg ggcaggcgcc
    11581 ccgtggacgg agagccccgg ctgccgctcc cggccaacga cgcacgtcgg gcgcaggggc
    11641 tgccacggcc gtctgccggg tgagacggtg agcgggatcg cccgccccgc ccggcagcgg
    11701 cctccgcacg gggcgccgcg tccggacatc cgccctgcgg ggacgatgcg ccgtcagccc
    11761 tcgtccccgc ggtggcggag agcaccggca gcgcggtgca gttcgtccgg gacgccgaac
    11821 gtcccgggcg cgtcgagctg ggggaggagc cgctcgacga gcgtttgttg ggccagcatg
    11881 aggcgctggt tctgctcgcg ggtgacggca ccgtcggcgg cgggcggcgg tgaaggcacc
    11941 ggaggcgaag ccgaccgcgt gcgacgcgac catgtcccgc gcggcggtcg acgcgtcgtt
    12001 ccgcccccgg gggtatctcc ccgctcgccc gaacgcagtt ggctgcccgc ggtggcgtgc
    12061 cggaggcgct cggacgaggc ggcgcgcgaa ctccggtccc gtggacggcc cttcgccgca
    12121 cgaccacgcg cccctgcgag ccctcagccc aggcggtggt cgaaccgcgg tgcgaccgcg
    12181 agcaggctgc tcaggtcggc ccccggcgcg tactcgaccg gctcggcccc cgcggagaag
    12241 agccgggcac ccgccgacgt gccgcccaac tccagtacgc cgtcgcgacg ttgcagccag
    12301 gtgccctcgc gcaggccgag gacgggcacg tcgttctcct cgaggaactg ggtgagccgc
    12361 tcctcacggg tctcgcccat gtgcgcgctc cccggctgcg ggtcgaggta gtgcgggttg
    12421 atctgaaacg ggacgagccc cagcgtcccg aacgacgtcg gctggacgat cggcatgtcg
    12481 ttggtggtcc gcagcgtcgg gcaggccatg ttggtcccgg cgctcgaccc catgtacggc
    12541 actccgtcct cctgtacgcg ccgggcgagt tcagggacga ggccgtgccc ctggagcgcc
    12601 cgcagcagcc ggaagctgtt gcccccgccg acgaacaccg cctcggccgc ggccacttcg
    12661 gcacggggat cgcccgagcc gtgcaggccg cgcacccgca cgcccaactc gcccatgaac
    12721 gccgcgacct tcgcggtgta ggcgtcgtgg tcggcgagcg cgtacgggac gaagagcagt
    12781 tcgcgcacgc cgccgaggtg ctcggcgacc acctcccgcg cgtggtcgag gtaaccccgt
    12841 ccgggggccg aggagttcga cagcaagagc agcttcacgg tgttccggcc tttctcttct
    12901 tcagttgcgg gacgtccggg gggttcggcc ccggacccga cgaggggtga gcagttcacc
    12961 gagaccctcc gcggcggagc gcagcggtat gagcaactcc tcgcggtcgt cggcgagttg
    13021 acggtgcggc ccgacgaggg tcagcgagcc caccggctgc gagcgcacca cgacgggcac
    13081 ggcgagcccc gccgtcgcgg ggtcgtactc gccctcggag tacgcgtagc cgtcggccgg
    13141 cacccggcac atcagctcct ccaactgcgc agggtcggtg acggtccgct cgctgaaacg
    13201 ggccatcggg cgaccgtaga gggcggcggc gcgtgccccc ggcgcgagca tcccgaagta
    13261 cgcgcgcgag gtggcgcccg cgtgccccgg gtagagctcc tcggcgaggc ggtaggtccg
    13321 cagcggtccg agcgtcccgt cggccgagtc gacgcacctg aggtgggcgc cgtcgggcac
    13381 ggcgaaaagc gcggtcaccc cgctctccgc ggcgagctcc cgcagcgccg gacgcaccag
    13441 ccccgccatc ccgccgtgcc gctcccaggc ggtggccatg tgccacacgg cgggccccag
    13501 ccggtagcgc cgggtgacgg cgtcggagac gaggaacccc cggtgcgcga gcgcggcgag
    13561 gagccgctgg gtgacggact tgtcccagcc gaactcggct gcgaggtcgg tcacccccca
    13621 ctcgtcgcgg tcgtgagtga aggcgagcag cacctggagc gtacggtccg cggtcttcag
    13681 cggagcccct cgatcggtag tcacccggcg taccctatcg gtatccacct ctgcttctca
    13741 catataggga aaaggttgct ctcgcggagc gcggaggagc aacctggcgg catcggccga
    13801 cggccaccgc cgctcacccg atgccgggcg ccacctcgaa gggcgcaacg gctcccgcgg
    13861 cccggagccg catcaccccg gcagcaacga cgctgcccct cgcacggccc ccgcccgtcg
    13921 cccaccagcg cggcggcccg ggcatcgccc ccaaggcgtc gccgtccgag tcccgaccgc
    13981 accaccccaa ggagcccacg gtgctcaagc acgtactgga cgtcctcgaa ctcctcgacc
    14041 gcccgcaggc cgacgggcac agcctcgacg cgcacctccg cgacgtcctc caccgggcgg
    14101 cgcagcaggc gggccgcacc gccgaggccg accgcgtcga gatctccgtc acccgcatcg
    14161 agggggcgca gggcggcacg gacttcgtga aggccgtcgt ccccggccgc gacggtgctc
    14221 gcgcgggcgg cagcgcaccc accctcggcg tactcggccg cctcggcggc gtgggcgccc
    14281 gcccggagcg gaccggcctc gtctccgacg cggacggcgc cgtcgccgcg ctcgccgcaa
    14341 cgtcgaagct gctcgacatg tacgggcgcg gcgacgtact cgacggcgat gtcatcctca
    14401 gcacccacgt ctgccccgac gcaccgaccc gcccccacga cccggtgccc ttcatggact
    14461 ccccggtctc catcctcgac tgcaaccgtc aggagatcga cggagcgatg gacgccgtcg
    14521 tctcgatcga caccacgaag ggcaaccgcc tcctcaacca ccgcgggctc gccctttccc
    14581 cgacggccaa ggaaggctgg atcctgcggg tcagcgacga cctgctcggc atcctggaga
    14641 ccgtcacggg cgaggacgcg cacgtgctgc cgatcaccac ccaggacatc accccgtacg
    14701 gcaacggcgt ccaccacatc aactcgatca tgcagccgtg cgtcgccacg tcggcgcccg
    14761 tcgtcggcct cgcgctgacc accgggccgg ccgtcgccgg ctgcgcgacg ggcgccagcc
    14821 acgagaccga catcgcagcc gccggccgct tcgccgtcga agcggcgaag gagtacggac
    14881 gaggggctgc ccgcttccac gacgcggaag agttcgcccg actcgtcgac ctctacgggc
    14941 cgatgacccg gctccagtcg acggcaggtg cgaccgagga ctgaccctcg ggccacccgg
    15001 ccgctgcggg ggagcggtcg aacagctcct ccgcaccccc caccccgcgt acgccccacg
    15061 cgcaccgcac ccgaaagacg acccctatga gcacctctcc agctcccgcc ccggaagcga
    15121 ggcgggccca ccccagagcc ctcgaaccgg tcaccctcgt cgtgacggtc ctgctgtccg
    15181 tgctgggagc cgtgatcggc ctcgtcctga tcaccaccct gggcatcgcc cccaacacct
    15241 cggtgatcgg ggcactcatc gccatgctca tcgggcgcct ctccttcgcg acgctctcgc
    15301 ggatgcgcga cccgcaccgc cagaacctcg tccagtcggc gatctccggc tccacgttcg
    15361 ccgcggccaa ctcgctcgtc acgccgatcg cggtgccgtt cctgctcggc gagcccggcc
    15421 tggtctggcc gatgctcggc ggcgcggtca tcggcctcgc cgtcgacagt tgggtgctct
    15481 accgcgtctt cgactcgcgg ctgctgcccg cgaccgccgc ctggcccgcc ggaatcgcgg
    15541 cagccgagac gatcaaggcg ggggacgagg gcggccgcaa ggcggggatg ctcggcgtca
    15601 gcgcggtcgt cggcttcctc ggctcgctct tcaagctccc gatgagcgcg gccggcgtcg
    15661 ccttcctcgg caacatctgg gcgctgctga tgttcggcgt cggcctgctc gtcgcgcagt
    15721 acgcgccgac gctgctcgac accgacctct cggcgaacca cgtgccgcac ggcgtgatga
    15781 tcggcgcggg actggtcgcc ctcgtgcagg ccgtccggct gatgcgggag cgcgacggcg
    15841 ggagcaagga ccagcagccc gctcgggagg ccgaggacgc cttcgacccg cagacgcgca
    15901 ccgtcgacgc ccgccgactg cggcgcggac tcctggaggg gctcgcgctc ttcctcgtcg
    15961 gcgccctctt cgtcgccctg accggcggca tcctcgccga catgagcggg ctcgggctcg
    16021 tcggctgggt gctcctcgcc ggtgtcgcgg cgctcgtgca ccagctcatc gtcgggctcg
    16081 cggcgatgca ctcggggtgg ttccccgcct tcgccgtgac cctgatcttc ctgatcctcg
    16141 ggctcgtcct cggcatcccg atggtgccgc tcgccctcct cgtcggctac gccgcctcca
    16201 cggggcccgc gttcgccgac gtcggcttcg acttcaaggc cggctggctg ctgcgcaagg
    16261 acgccgtgcc ctggcacccc tacgagatgg cggggcggcg ccagcagtac gtcgcgcagc
    16321 tcgtcggctt cgccgtcgcg atcctcgtcg tggtcgtcgc gtggaagccg ttcttcgagg
    16381 acggccgggt gccgccggtg gcgcaggtct acgtcgacac tctcaaggcc ggcctctcgg
    16441 acacgcatgc gctgacgatg atggcgctct gggcgatccc gggcgcgctc gtccagctcc
    16501 tcggcggctc ctcccgccag atgggcgtcc tgctggcgac gggcctcctc gtcgcgacgc
    16561 cgcaagcggg ctggctcgtc ctcgccgcgc tcgccgtccg cttcggctac gcccgcaggg
    16621 cgaagcgccg ggcggactcc ggagacgggc aacaggcagc cgccgacaac gacttggcgc
    16681 tcgtcggcgc gggtctcgtc gcgggcagct cgctcaacga cgtaagccag atctacaagg
    16741 cggtgtga
//
