LOCUS       reptomyces_RBGC_162609 15114 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_162609
VERSION     Streptomyces_RBGC_162609
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001650215.1
  ORGANISM  GCF_001650215.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..1245)
                     /protein_domains="PF01569"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653683"
                     /pseudo=False
                     /translation="VSHIATRPFLLALGAASLLATSTAVPTAVAAPAEPRTPVVLDWYD
                     TTAETIAAAGAPTQVTNSRTWAVSWLAGARATHGVPAGVDRSDYQDAALASAVHRSLVA
                     LAPARTEQLDAAFRRTLDQIPDGPAENRGVAAGERQARSVLASREGDGLDPASVDAPFT
                     VPPASPGVWQPTPPSYAPATQYGNRLARPFVLSGAGQFRLGPPPALDSRTYRSDLAEVR
                     AYGAADSTRRSARQTETANFWYGSSLTLYTEPLRVALARSARSVEERAKLVALFHIASV
                     DTQIATSDTKYTYQRWRPVTAIRTGAIDPDPGWTPLHNTPAHPDYPSGHNTYSGAAEEI
                     LSALVGPRTAPFELTSSTAPGVTREYTGWHQLTAENVDARIFSGIHTRSADEAGVTLGK
                     KVAAQVLRESGRLFR*"
     CDS             complement(1257..2011)
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653684"
                     /pseudo=False
                     /translation="MATHAGGLTATAREASAAVRIEGLVRAFGTRTVLDGLDLTLRPGE
                     FVAMLGRSGSGKSTLLRALAGLDHEAGGEGELSAPDHVSVVFQDARLLPWKRVLANVTL
                     GLTGADAGERARTALDEVGLAGREDAWPVELSGGEQQRVSLARSLVREPELLLADEPFG
                     ALDALTRGRMHTLLARLYERHRPAVLLVTHDVDEAIALADRVVVLDGGRIAADLAVELP
                     APRRHGTPEYAALRTRLLARLGVDGPDHL*"
     CDS             complement(1988..2853)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653685"
                     /pseudo=False
                     /translation="MSTDVTDERLSLVKTAPTAPASPAARRGRTRRRLGPGRPIPYGRA
                     LGPVLLLAIWSGGSATGLIDARNLSAPWTVVATAGDLIADGRLQTNVWTSAERAVSGLA
                     YGVAAGLVLALVAGLSRLGEGVIDGPVQIKRGIPTLALIPLLILWFGIGESMKVITIAL
                     SAFVPVYIHTHNGLRTIDARYVELAETLGLSRPRFLLHIVLPGALPGFLLGMRFAVTAA
                     WLALAVVEQVNATSGIGYMMGLARTYGQTDIIIVGLVVYGLLGLLSDGLVRLVERKVLS
                     WRRTLAD*"
     CDS             complement(2851..3908)
                     /protein_domains="PF09084"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653686"
                     /pseudo=False
                     /translation="MPRHTPLLTAALACTLLLAGCADNTTSSTTADSKNVAHIKIPDKV
                     KAATSITIGAPDTQVALKLSGQIKKLPFKVKWANISGGPQCSEAFRAHSLDLCASAEIP
                     SIHAHWTGLDTKLVAAEFRKDPLKHPVYELGIAPGAHIDTLADLRGKKIAYSPGQAQGA
                     LVLRILAKAGLTKKDVQLVELPSTGDVYPTALGSHQVDAAPLGGVNIKRYPAKYGKDGG
                     KTIQHGLRDDPAHLWAPTASVSDPQKAAAIREFIKFWARSEIWVEQHPKEWIDGYYVKD
                     QGLTRADGEYLVKQNGQVDIPDDWTPAIARQQKTVDLLAKETGQKKFDTGILFDRRYES
                     VAADAIAKAGKP*"
     CDS             4353..4747
                     /protein_domains="PF00583"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653687"
                     /pseudo=False
                     /translation="MRTTQARVGQPYGWRSASRTEDEWEAKIQACPLRQYWLITHEQET
                     AGIVCLEPQHGGDVEITAFGLLPEYVGKGLGGYALTLALRQAWATEPVGADAVRRVWLH
                     TSTHDHPHALRNYQQRGLRRYRVEAQQ*"
     CDS             complement(4795..5411)
                     /protein_domains="PF00440"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653688"
                     /pseudo=False
                     /translation="VKAVAQVTGGRPMRSDTERNRRYLIKAAARLFENSPTPVSLAEIA
                     KHAEVSTATAYRHFSSVEEILHAFRAEVGFELCDFSARQTTRGMARLEAVSRCWVSLVL
                     EHGGAMAQMRSHRGYLERLREGTGYLAPQAEALAEPLRQTTEELGLGDLGDEALYLWNT
                     LFDPRDILDLIKSGRTEEEAATRLVAALRGALTGWSHGAAIG*"
     CDS             complement(5409..6577)
                     /protein_domains="PF00155"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653689"
                     /pseudo=False
                     /translation="MPPTITTQPPLFATAEAVARIAAASRRTQQPQSKGDLVSLAMGEP
                     DFDTPPSVTEAAHASLCAGRTHYSPLLGEPALREALADKLTGIAGAPVSASDILITQGG
                     TAGLAASILGIVDPGDKVVIPDPTYSLYADLVSMAGGTVVPVPLAPDLHWDLDRLADAL
                     TDAKLFVFCNPSNPTGIVHSRDELDALAELLDGTSTIVISDEAYSDLDYTGRPFTSTIS
                     IDGLRDRTVYCQTFSKSYAMTGWRVGYLWGPAPLIQASARIHNTFNGSANTVVQDAALA
                     AVQSCDEDVARMRAAYERRGEIMRTELAAIPGLTLSAPEGAFYQFPRYDLDVPSVEVVA
                     ALRTHGVAVRPGSEFGARGEGHLRLSYAASEESITEGVRRLARGLSALR*"
     CDS             complement(6603..7399)
                     /protein_domains="PF00106"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653690"
                     /pseudo=False
                     /translation="VTTSGGRTALITGAGSGMGLETARLLARDGTAVVLIGRRQEALDD
                     VAATIRAEGGTALAIAADITRADDVTRVLDRVRSELGPVDVLVNNAGSASSVLNPQWLP
                     HDEWRQVLDVNLTAVFQLTQAVLPDMLDRGTGTIVTVSSLAAVNPNLLGGAAYGAAKAG
                     VRNFMTFLHNTFRNQGLRAITVLPGEADTPILDNRARPPAPEERANMVQPEDVAEAIRL
                     AVTLPQRVVLQEIVVAPTRQRDTSADLEISRWAGAPADAAPQA*"
     CDS             complement(7466..8469)
                     /protein_domains="PF02626"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653691"
                     /pseudo=False
                     /translation="MKTVALEITSTGWITTFQDLGRRDTERRGVPTGGAADQHSAAVAN
                     LLVGNPRGATLIENLGGELRLVPDADVLLAVTGAPARVTVGGGAVESWSPLVVPAGHEV
                     RIQGDVSRGTRTYLAVNGALTAETLLGSAAPDARMGFGQAVVRGSCVLLDTEFRGFSRR
                     LFEAPLFRLPVPVPRFDAGPWDIDVVPSHGIHTITGIREVIEEATYVVTNRSNHVGLRL
                     DGPVLHPDSDTEIVSHGVPVGALQIPHADELIVLGRYRSLTAGYPIVGVASRASLPLLG
                     QAGPGRELRFRWTDRESSLRRFARREAEVRALEHAATEAFGALGFMAPLSHTR*"
     CDS             complement(8467..9203)
                     /protein_domains="PF02682"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653692"
                     /pseudo=False
                     /translation="MTTAQYGAITVEPFGDSAVMVTIPHADQAIRKSGIVAFRERFLAH
                     RPHGVLDVVSGLESLLIEFDPLTTALQHVEYAARLLAAWAPAPSDGPDHLRTVRQFAIP
                     VVFDDETGPDLASVADDMGLAPAEVVEAIAESSFTISLLGAAMAPMMDGLKVPRPVRRL
                     AEPRTDVAPGAIMIAGTHAIIQPFPGPTGWRVVGRTPRTIVDISRPDPVSFGTGDIVRF
                     VPVTRDEAAVLGPGFLLPVGESV*"
     CDS             complement(9224..10029)
                     /protein_domains="PF03746"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653693"
                     /pseudo=False
                     /translation="MGINSVAVVADLGESFGNYTIGDDGALLGLVTSSNIACGFHAGDP
                     RIMDRTVADCVERGIELGAHPGYPDLVGFGRRLIEATEEEIRTDVLYQLGALDAFARVH
                     GGTISHVAPHGRMGSIAQTDAKHARAITDAIAAYNTDYVVICQRGLLAEESRKRGLEVG
                     YVFLADRGYGDDGMPVSRSHEGGLIYDPELIGQRSVQVVQEGTVRSVNGNVVPLGHDAD
                     VLLLHGDHPSVLENGTALRKALGAADIRVAGLRDVLAEKAEVALAR*"
     CDS             complement(10049..11421)
                     /protein_domains="PF07690"
                     /protein_domains="PF00083"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653694"
                     /pseudo=False
                     /translation="MTTSDRLDRTSDRHEAAPEESGATAVDAAANDTVVRKATVAGAIG
                     SFVEWYDYGIYGLLVTYLAINIMGEADAGNLFLTNVGFLVSFIARPFGSVICGYLGDKI
                     GRKSLLATLLVLISAATAAIGLIPSSTVIGVAAPVLLVLLRVLQGFSAGGEVAGAMSFV
                     GEYAPDARRNYMMSFIAVGSFIALMFGSAFSAILITTLGEDTMTSWAWRVPFLLAVPLG
                     YVGFYIRSRLEETPHFKVLREQNTVARNPLRDALTSPRHLKAIALTIFLPALNGPGYYL
                     LFVYMPTYMKTSLGEHNFSMLRALMVTAFSLVAIAVCIPLMARLSDRIGRKPVLAYSAI
                     AMALVSYPMFRLITTGEFGLACIGTIVLAVAFSGHAAVVHTVLAEMFPTTVRYSAYSIG
                     FSISTIIFGGSAPLLMTELIESTGSNLIPAFASIITALITLVAIAFVRETKGQPLASS*
                     "
     CDS             complement(11470..11684)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MSAPLCGPVPWRLLPAPTRAHSDGNTAVCPASSPRRSCTGGFLNS
                     TEATQPPRDAVTAFPVETGTVTTFSA"
     CDS             11993..12633
                     /protein_domains="PF03737"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653695"
                     /pseudo=False
                     /translation="MTQDNVRVDTAWERVDGHVLDQFRTHSVANLGDALDRLNIVDGGI
                     APIWNGAKAVGTALPVLTVAGDNKAVIAALEHIRPGDILVINAFGYDGRAIIGDNLAQR
                     FAAYGAAGAIIDGYVRDAAIIEELGIPIFARGLTPAGPFKNGPGTIGESVAIGGVVVNP
                     GDIIAADGDGVIVIPPRRADEALKSVSEIVAREAALDAEVEALRSKTAAS*"
     CDS             complement(12646..13076)
                     /protein_domains="PF12680"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653696"
                     /pseudo=False
                     /translation="MTAAARFRAAVDNGDLAALEDLFTDDIRFYSPVKFTPFEGKPMVL
                     GLFGVLLRTFENFRYVGHHDGTAETSADGGVSASAVLLFRAVVGGKEIHGIDLLHFDDD
                     GRIKEFTVMVRPQSAVHALGEAVLAGLVADGLLPAPVER*"
     CDS             13167..13738
                     /protein_domains="PF10400"
                     /protein_domains="PF03551"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653697"
                     /pseudo=False
                     /translation="MALRHAVLAALLDEELSGYQLVKAFDLGVANFWHAQPQQVYAELA
                     RLEKDGLITGREVVQDTRPNKRLFQVTDAGLAELDHFTATAAKPSFVRDDLVVKVQAAD
                     HVDTRTLIARLTERAALAQAKIDLFGKLLRGMRGDRTEEEFLRHGERIGPYLTCLRGLA
                     FEQGNLDWCERTVTVLREREGADAPRR*"
     CDS             complement(13776..14323)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653698"
                     /pseudo=False
                     /translation="MTIAGPHLAAVRDSSCPSCTNAPSSEEHERPETARERVNRKWNEI
                     LQETRVAQTGVQILFGFLLSLAFTPAFGDLEVFDRTLYVVTVALGASSVAALIAPVSIH
                     RFLSGLRMKDEVVEAAGRLMVCGMVLLALTIACTLLLILNVVTDSVVAEVIVGLVMLWF
                     AICWYVIPLRLRRKSRRRR*"
     CDS             complement(14321..15114)
                     /protein_domains="PF04542"
                     /protein_domains="PF04545"
                     /protein_domains="PF04539"
                     /protein_domains="TIGR02980"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4653699"
                     /pseudo=False
                     /translation="MTAVRTRSKHSHDDAPDTSAEFRRIATLPEGPEREALRQDVVRAW
                     MPMAERLARQFRNRGESAEDLRQVAMLGLVKAVKRYEPDRGTAFASFAVPTVVGEIKRH
                     FRDHMWGVHVPRRVQELRNRVRAAAQELTRTPDDRSPSVSAIVEHTGMSEEDVLLGMEA
                     MESFSALSLDAELPGAEDGYSLADTLGAPEPSYDRVIQREALKPRLRALPERERHILYL
                     RFFREETQGRIAEQLGISQMHVSRLINRTCARLHDQIEAPAA*"
ORIGIN
        1 tcagcggaag agcctcccgg attcgcgcag tacctgggcg gccaccttct tgccgagggt
       61 gacgcccgcc tcgtccgcgg agcgggtgtg gatgcccgag aagatccggg cgtcgacgtt
      121 ctcggccgtc agctggtgcc agcccgtgta ctcgcgcgtg acacccggcg cggtggaact
      181 cgtcagctcg aacggcgcgg tgcgcgggcc gaccagtgcg gacagtatct cctccgccgc
      241 tcccgagtag gtgttgtggc cgctcgggta gtccgggtgc gccggtgtgt tgtgcagcgg
      301 tgtccagccg gggtcggggt cgatggcgcc ggtgcggatg gcggtgaccg ggcgccaccg
      361 ctgatacgtg tacttggtgt cggaggtggc gatctgcgtg tccaccgacg cgatatggaa
      421 cagcgccacc agcttcgccc gctcctccac cgaccgggcg gaccgggcca gcgccaccct
      481 cagcggctcg gtgtagaggg tcagcgagga gccgtaccag aagttcgcgg tctctgtctg
      541 ccgcgcggag cgccgtgtgc tgtccgccgc gccgtaggcg cgcacctcgg ccaggtccga
      601 ccggtacgtc cgcgagtcca gcgccggggg cggcccgagc cggaactgac cggcacccga
      661 caggacgaac ggccgcgcga ggcgattgcc gtactgcgtg gcgggagcgt acgacggcgg
      721 cgtgggctgc cagaccccgg gggacgcggg cggcacggtg aacggggcgt cgaccgacgc
      781 cgggtccagg ccgtcgccct cccgggacgc gaggacggac cgggcctgcc gctcaccggc
      841 cgccacgccc cggttctcgg ccggtccgtc cgggatctgg tccagggtac ggcggaacgc
      901 ggcgtccagt tgctcggtgc gcgccggggc gagggccacc agggagcggt gtacggcgga
      961 ggccagggcc gcgtcctggt agtcgctccg gtcgacgccc gcgggcaccc cgtgggtggc
     1021 gcgtgccccc gcgagccagc tcaccgccca ggtgcggctg ttcgtcacct gggtcggcgc
     1081 cccggccgcc gcgatggtct cggccgtggt gtcgtaccag tcgagcacca ccggggtacg
     1141 gggctcggcg ggcgcggcga cggcggtggg gaccgccgtc gaggtggcca gcagcgacgc
     1201 ggcgccgagg gccaggagga acggtcgggt ggcgatgtgg ctcaccggca aactcctaaa
     1261 gatggtcggg tccgtcaacg cccagccggg cgagcagtcg ggtccgcagc gcggcgtact
     1321 cgggggtgcc gtgccgccgc ggcgcgggca gctccacggc gaggtcggcg gcgatccggc
     1381 ccccgtccag gaccaccacc cggtcggcga gtgcgatggc ctcgtccacg tcgtgcgtga
     1441 ccagcagcac ggcgggacgg tgccgctcgt acaggcgggc cagcagcgtg tgcatacggc
     1501 cccgggtgag cgcgtcgagt gcgccgaacg gctcgtccgc gagcagcagt tcgggctcac
     1561 gcaccaggga ccgggcgagc gagacccgct gctgctcacc gcccgacagc tccacgggcc
     1621 aggcgtcctc ccgcccggcc aggcccacct cgtcgagcgc cgtgcgggcc cgttccccgg
     1681 cgtccgcgcc ggtgagcccc agggtgacat tggccagcac ccgcttccac ggcagcaacc
     1741 gggcgtcctg gaagaccacc gacacatggt cgggtgcgct caattcgcct tcgccgcccg
     1801 cttcgtggtc gagtccggcg agggcgcgca gcagggtgct cttgccggag ccgctgcggc
     1861 cgagcatggc cacgaactcc ccggggcgca gggtcaggtc gagcccgtcc agcaccgtgc
     1921 gcgtgccgaa ggcccgtacg agtccctcga tgcggacggc cgcggaggct tcccgagcgg
     1981 tggccgtcag tccgccagcg tgcgtcgcca tgacagaacc ttcctctcca cgagccgtac
     2041 cagtccgtcg gagagcagcc cgagaagtcc gtacacgacg agaccgacga tgatgatgtc
     2101 ggtctgcccg tacgtgcgcg cgagccccat catgtagccg atcccgctgg tggcgttgac
     2161 ctgttcgacg acggccaggg ccagccaggc ggcggtcacg gcgaagcgca tcccgaggag
     2221 gaaaccgggc agcgcgcccg gcaacacgat gtgcagcagg aagcgcgggc ggctcagccc
     2281 cagcgtctcg gcgagttcga cgtaccgtgc gtcgatggtg cgcagcccgt tgtgggtgtg
     2341 gatgtagacc gggacgaagg cgctgagggc gatcgtgatg accttcatgg actccccgat
     2401 gccgaaccac aggatcagca gcggtatgag cgcgagggtg gggatgcccc gcttgatctg
     2461 cacgggaccg tcgatcactc cctcgccgag cctgctgagc cccgcgacca gcgccagcac
     2521 gagcccggcc gccactccgt acgccagacc ggacacggcc cgctcggcgg atgtccacac
     2581 gttggtctgg agcctgccgt ccgcgatgag gtcgcccgcc gtggccacca ccgtccaggg
     2641 ggcggacagg ttgcgcgcgt cgatgaggcc ggtggccgaa ccgcccgacc agatcgcgag
     2701 cagcagaacg gggccgagcg ccctgccgta cgggatgggc cgcccggggc cgaggcggcg
     2761 gcgcgtgcgc ccgcgccggg cggccgggga cgcgggagcg gtcggcgccg tcttgacgag
     2821 ggacagccgc tcgtccgtga cgtccgtgct catggcttcc ccgctttcgc gatcgcgtcg
     2881 gcggcgaccg actcgtaccg gcggtcgaag aggattcccg tgtcgaactt cttctggccc
     2941 gtctccttcg ccagcaggtc gaccgtcttc tgctggcgcg cgatggccgg cgtccagtcg
     3001 tccgggatgt ccacctgtcc gttctgcttg accaggtatt cgccgtccgc gcgggtgagg
     3061 ccctggtcct tgacgtaata gccgtcgatc cattccttgg ggtgctgctc gacccaaatc
     3121 tccgaccggg cccagaactt gatgaactcc ctgatggcgg ccgccttctg cggatcgctc
     3181 acggatgcgg tcggcgccca cagatgggcg ggatcgtccc gcaggccgtg ctggatggtc
     3241 ttcccgccgt ccttgccgta cttcgccgga tagcgcttga tgttgacgcc gccgagcggc
     3301 gcggcatcca cctggtggct gccgagcgcg gtcgggtaca cgtcccccgt gctgggcagc
     3361 tcgaccagtt gcacatcctt cttggtgagt cccgccttcg ccaggatccg cagcaccagc
     3421 gcgccctggg cctgccccgg gctgtacgcg atcttcttgc cgcgcaggtc cgccagggtg
     3481 tcgatgtggg caccgggagc gattccgagc tcgtagacgg ggtgcttcag cggatccttg
     3541 cggaactccg cggccacgag tttggtgtca agaccggtcc agtgagcgtg tatcgacgga
     3601 atctccgccg acgcgcacag gtccagggaa tgcgcgcgga atgcctcgga gcactgcggt
     3661 cccccactga tattggccca cttgaccttg aagggaagct ttttgatctg ccccgagagc
     3721 ttcagcgcca cctgagtgtc cggcgcgccg atcgtaatcg acgtggcggc tttcaccttg
     3781 tccggaatct tgatgtgggc gacgttctta ctgtcggcgg tggtcgatga ggtggtgttg
     3841 tcggcgcagc cggccagcag caaagtgcag gccagagcag ccgtgaggag cggggtgtgc
     3901 ctgggcatac ggggttcccg ggggcagggc gtacggcatc ggcgcgtacg gaaaatgaac
     3961 tggtatcgcg gggggagaag cgcgggggaa gcgcgcgcgg atgagcggtg tgcgtgctgc
     4021 tgaaattcag ctacacagcg cggcggcgag gcgcgtcaga tcggcaggac accgctgcgt
     4081 gaaccgcaga gaaatcggca tgccgctgaa gctagcgagt acgtcaagag cgggtcaagt
     4141 gcccgttcac gcttccggaa agcggcaatc acgacttcgt acggtcgcca tatgcgcgtt
     4201 acatgtacgc gccgagcggc atggccgata gcctgccgct gtgaaaagga ccgtcacgac
     4261 gtacttggag atgaccgctc cggatgccct ccgtccggcc tcggtggcat cggctctcgg
     4321 cctgctccgg atcgacagct cctcgcctct gatgcgcacc acacaggccc gggtcgggca
     4381 gccgtacggc tggcgtagcg cctcccgtac ggaggacgaa tgggaagcga agatccaagc
     4441 gtgtccgctg cgccagtact ggctcatcac gcacgaacag gagacggcgg ggatcgtctg
     4501 cctcgagccg cagcacggcg gggacgtgga gatcaccgcc ttcgggctgc tgccggagta
     4561 cgtcggcaag ggcctcggag ggtacgccct gacgctcgca cttcgacaag cctgggcgac
     4621 cgagcccgtg ggcgccgacg cggtacgccg ggtgtggctc cacacttcta cgcatgacca
     4681 cccgcacgca ctgcgcaact atcagcagcg cggcctgcgt cggtaccgcg tcgaagccca
     4741 gcagtagcgg gattccccct gagggacccg cggctcgcgc cccgacccct cactcacccg
     4801 atcgcggctc cgtgggacca gccggtcagg gcgccgcgga gcgcggccac caggcgggtg
     4861 gcggcctcct cctcggtgcg tccgctcttg atgaggtcga ggatgtcgcg tgggtcgaac
     4921 aacgtgttcc acaggtacag ggcttcgtcc ccgaggtctc cgaggccgag ttcctcggtg
     4981 gtctgccgca gtggctcggc gagcgcctcg gcctgcgggg cgaggtagcc ggtcccctca
     5041 cgcagccgct cgaggtagcc gcggtgcgaa cgcatctgcg ccatcgcgcc gccgtgttcg
     5101 aggacgaggg aaacccagca gcgcgatacc gcctctagtc tcgccatgcc ccgtgtggtc
     5161 tgccgtgcgc tgaagtcaca cagttcaaag cccacttcgg cgcggaaggc gtgcaggatc
     5221 tcctcgacgg aggagaagtg ccggtaggcc gtcgcggtgg acacctcagc gtgcttggcg
     5281 atctcggcca ggctgaccgg cgtcggcgag ttctcgaaca gccgcgcggc ggccttgatg
     5341 aggtacctgc ggttgcgttc ggtgtcactg cgcatgggcc ggccccccgt gacctgcgcg
     5401 acggccttca ccgaagagcc gagaggccac gggccagtcg gcggacgccc tcggtgatgg
     5461 attcctcgct ggccgcgtac gacagccgga ggtgcccctc gccccgggct ccgaactcgc
     5521 ttccgggccg gacggcgacg ccgtgggtgc gcagcgccgc tacgacctcc acggagggca
     5581 cgtcgaggtc gtagcgcggg aattggtaga aggctccttc cggcgcgctg agggtgaggc
     5641 cggggatcgc ggccagttcc gtacgcatga tctcgccgcg ccgctcgtac gcggcgcgca
     5701 tgcgggcgac gtcctcgtcg cagctctgta ccgcggcgag ggcggcgtcc tggacgacgg
     5761 tgttcgcgga gccgttgaag gtgttgtgga tgcgggcgga cgcctggatg agcggcgccg
     5821 gtccccagag gtagccgacg cgccagccgg tcatggcgta gctcttggag aaggtctggc
     5881 agtagacggt gcggtcgcgc aggccgtcga tcgagatcgt cgaggtgaag ggccggccgg
     5941 tgtagtcgag gtcggagtac gcctcgtcgg agatgacgat cgtggaggtg ccgtcgagca
     6001 actcggcgag cgcgtcgagt tcgtcgcggc tgtgcacgat gccggtcggg ttgctgggat
     6061 tgcagaagac gaagagcttg gcgtccgtga gggcgtcggc gagccggtcg aggtcccagt
     6121 gcaggtccgg cgcgaggggg acgggcacga cggtgccccc ggccatgctg accaggtccg
     6181 cgtagaggga gtaggtgggg tcggggatga ccaccttgtc gccggggtcg acgatgccga
     6241 ggatcgaggc ggcgagcccc gcggttccgc cctgggtgat caggatgtcg gaggcggaga
     6301 ccggcgcccc ggcgatgccg gtgagcttgt cggcgagggc ttcgcgcagg gcgggttcgc
     6361 cgagcagcgg agagtagtgc gtgcgtccgg cgcacagcga ggcgtgggcc gcctcggtca
     6421 ccgagggggg tgtgtcgaag tcgggttcgc ccatggcgag ggagacgagg tcgcccttcg
     6481 actgcggttg ctgcgtccgg cgggaggcgg cggcgatccg ggcgacggcc tcagcggtgg
     6541 cgaacagggg cggctgcgtg gtgatggtgg gcggcatgcg ctcctcctgg tggcgggttg
     6601 gtcaggcctg cggtgcggcg tcggcgggtg cgcccgccca acggctgatc tcgaggtcgg
     6661 cggaggtgtc gcgctggcgc gtgggggcga cgacgatctc ctggaggacg acgcgctggg
     6721 gaagggtgac ggcgaggcgg atggcctcgg ccacgtcctc gggctgcacc atgttggcgc
     6781 gttcctccgg cgccgggggc cgggcacggt tgtcgaggat gggggtgtcc gcctcgccgg
     6841 gcagcacggt gatcgcccgc agcccctggt tgcggaaggt gttgtgcagg aacgtcatga
     6901 agttgcgcac cccggccttg gccgcgccgt acgcagcgcc gccgagcagg ttggggttga
     6961 cggcggcgag cgaggaaacg gtgacgatgg tcccggtgcc gcggtcgagc atgtcgggca
     7021 gcacggcctg ggtgagctgg aagaccgccg tgaggttcac gtcgaggacc tggcgccact
     7081 cgtcgtgcgg aagccattgc gggttgagca ccgacgaggc actgcccgcg ttgttgacga
     7141 ggacgtcgac cggtccgagt tcggagcgga cacggtcgag gactcgtgtg acgtcgtccg
     7201 cgcgggtgat gtccgcggcg atggcgaggg cggtcccgcc ctcggcgcgg atcgtggccg
     7261 cgacgtcgtc gagtgcctcc tgcctgcggc cgatgagcac cacggcggtg ccgtcccggg
     7321 ccagcagccg tgcggtctcg agtcccatcc cgctgcccgc tcccgtgatg agcgcggtcc
     7381 tgccgccaga cgtcgtcacc gttcgtcctc catggctgac tccatgactg atatgagatg
     7441 cacttttcaa gtgagaatac attctcatct tgtgtgggac aagggtgcca tgaagccgag
     7501 agcgccgaat gcctccgtgg ccgcgtgttc cagtgcgcgc acctccgcct cgcgccgcgc
     7561 gaaccggcgc agcgagctct cgcggtcggt ccagcggaac cgcagctccc gccccggacc
     7621 ggcctgcccg agcaagggca gggacgcccg cgaggcgaca ccgacgatcg ggtagcccgc
     7681 ggtcaggctc cggtagcggc cgagcacgat cagctcgtcc gcgtgcggga tctgtagtgc
     7741 gccgacgggc accccgtgcg acacgatctc ggtgtcggag tccgggtgga gcaccggccc
     7801 gtcgagccgc agcccgacgt ggttggagcg gttggtgacg acgtaggtcg cctcctcgat
     7861 cacctcacgg atcccggtga tcgtgtggat cccatggctc gggacgacat cgatgtccca
     7921 gggcccggcg tcgaagcgcg ggaccggaac gggaagccgg aacaacggcg cttcgaacag
     7981 ccgccggctg aacccccgga attccgtgtc cagcaggaca cacgaacccc ggacgacggc
     8041 ctgcccgaac cccatccggg catccggggc ggcgctgccc agcagggtct ccgcggtcag
     8101 cgcaccgttc acggccagat aggtacgggt cccccggctc acgtccccct gtatccgtac
     8161 ctcgtgtccc gccggcacca ccagcggcga ccagctctcg acggccccgc cgcccacggt
     8221 gacccgggcg ggggcgccgg tcacggcgag caggacgtcg gcgtcgggca cgagcctcag
     8281 ttcgccgccg aggttctcga tcagggtcgc cccgcggggg ttgcccacga ggaggttggc
     8341 gacggccgcc gagtgctggt cggccgcgcc gccggtgggg acaccgcgcc gctccgtgtc
     8401 gcgacggccg aggtcctgga acgtcgtgat ccatccggtg ctggtgatct cgagcgccac
     8461 ggtcttcata cggactcccc caccggcagc aggaaaccgg gccccaggac cgcggcctcg
     8521 tcccgggtga cggggacgaa gcgcacgatg tcgccggtgc cgaacgagac ggggtccggt
     8581 cgggagatgt cgacgatggt gcgcggggtg cgcccgacca cccgccagcc ggtcggtccg
     8641 gggaacggct ggatgatcgc gtgggtaccg gcgatcatga tcgctccggg ggcgacatcg
     8701 gtccggggct cggcgagccg gcgcaccggc ctgggcacct tgagcccgtc catcatcggg
     8761 gccatcgccg cgccgaggag ggagatcgtg aagctggact ccgcgatcgc ctcgacgacc
     8821 tcggcggggg ccaggcccat gtcgtcggcg acggacgcca gatcgggacc ggtctcgtcg
     8881 tcgaagacga cgggaatggc gaactgccgg accgtccgca ggtggtccgg accgtccgac
     8941 ggtgccgggg cccacgccgc cagcagccgg gccgcgtact ccacgtgctg gagcgcggtc
     9001 gtcagcgggt cgaactcgat gagcagggac tcgagaccgg agacgacgtc cagcacaccg
     9061 tgggggcgat gggccaggaa ccgctcgcgg aaggccacga tcccggactt gcggatggcc
     9121 tggtcggcat gggggatggt caccatcacc gccgagtccc cgaagggctc gacggtgatg
     9181 gcaccgtact gtgctgtggt catctcctga tgggctcggc cctcagcggg cgagcgcgac
     9241 ctccgccttc tccgccagga cgtcccgcag accggcgacg cggatgtccg ccgcgccgag
     9301 cgccttccgc agcgcggtgc cgttctcgag gacggacggg tggtcaccgt gcaggagcag
     9361 gacgtcggcg tcgtgtccga gcggaaccac gttgccgttg accgagcgta cggtgccctc
     9421 ctggacgacc tggaccgagc gctgcccgat cagctcgggg tcgtagatca ggccgccttc
     9481 gtgcgagcgg gagacgggca tgccgtcgtc gccgtatccc cggtcggcca ggaacacgta
     9541 gccgacctcg agtccgcgct tgcgcgattc ctcggcgagc agaccgcgct gacagatgac
     9601 gacgtagtcg gtgttgtacg cggcgatcgc gtcggtgatg gcccgcgcgt gcttggcgtc
     9661 ggtctgcgcg atcgagccca tccggccgtg cggggccaca tggctgatcg tgccaccgtg
     9721 caccctcgcg aaggcgtcga gtgcgccgag ctggtacagg acgtcggtgc ggatctcttc
     9781 ctcggtcgcc tcgatgagcc ggcggccgaa gccgacgagg tcggggtatc cggggtgggc
     9841 gcccagctcg atgccgcgct cgacgcagtc ggcgacggtc cggtccatga tgcgcgggtc
     9901 tccggcgtgg aagccgcagg cgatgttcga cgaggtgacg aggccgagca gagcgccgtc
     9961 gtcgccgatc gtgtagttgc cgaagctctc accgaggtcg gcgacgacgg ctacggagtt
    10021 gattcccatg gtgtctcccg gggtgtttca gctggatgcg aggggctggc ccttggtctc
    10081 tcgcacgaag gcgatggcga ccagagtgat cagggcggtg atgatggagg cgaaagccgg
    10141 gatcaagttg gagccggtcg actcgatcag ctcggtcatc agaagcgggg cacttccccc
    10201 gaagatgatc gtggagatgc tgaatccgat gctgtaggcg gagtagcgca cggtggtcgg
    10261 gaacatctcg gcgaggacgg tgtggacgac ggcggcgtgg cccgagaagg cgaccgcgag
    10321 aacgatggtg ccgatgcagg ccaggccgaa ctctcccgtg gtgatgagcc ggaacatcgg
    10381 gtacgagacg agggccatcg cgatggcgga gtaggcgagg acgggcttgc ggccaatccg
    10441 gtccgagagg cgtgccatga gcgggataca gaccgcgatg gcgaccaggc tgaacgccgt
    10501 gaccatgagg gcccgcagca tcgagaagtt gtgctcgccg agcgaggtct tcatgtaggt
    10561 gggcatgtag acgaacagca ggtagtagcc ggggccgttg agcgccggga ggaagatcgt
    10621 gagcgcgatc gccttcaggt ggcgcgggga ggtcagggcg tcccgcagcg ggttgcgcgc
    10681 gacggtgttc tgctcgcgca gcaccttgaa gtgcggggtc tcctccagtc ggctgcggat
    10741 gtagaagccg acgtagccga gcgggacggc gaggaggaac ggcacccgcc aggcccagga
    10801 ggtcatggtg tcctcgccga gcgtcgtgat gaggatggcg gagaaggcgc tgccgaacat
    10861 cagggcgatg aacgagccga cggcgatgaa gctcatcatg tagttgcggc gtgcgtccgg
    10921 ggcgtactcg ccgacgaagg acatggcacc ggccacctcc ccgcccgccg agaagccctg
    10981 gagcacccgg aggaggacca ggaggacggg tgcggcgaca ccgatgacgg tggaggacgg
    11041 gatgagaccg atggccgcgg tcgcggcgga gatcagcacc aggagggtgg ccaggaggct
    11101 cttccgcccg atcttgtccc cgaggtatcc gcagatgacg ctgccgaacg ggcgggcgat
    11161 gaagctgacc aggaacccga cgttggtgag aaagaggttt ccggcgtcgg cctcccccat
    11221 gatgttgatc gcgagatagg tgacgagcag gccatagatg ccgtagtcgt accactcgac
    11281 gaaggagccg atcgcaccgg cgacggtggc cttgcggacg accgtgtcgt tggcggcggc
    11341 gtcgaccgcg gtcgcgccgg actcttccgg cgctgcctcg tgacggtccg atgttctgtc
    11401 aagccggtct gacgttgtca ttcgcgttca ctttcggtgt cgcggactcc ggaacggcgt
    11461 cctgagaatc atgcgctgaa cgtggtcacc gttccggtct ccacggggaa cgcggtgacg
    11521 gcatctcggg gtggctgtgt ggcttcggtg ctgttcagga atccgcccgt acaggacctg
    11581 cgggggctcg atgccggaca caccgccgtg ttgccgtcgc tgtgcgcccg agtgggggcc
    11641 gggaggagac gccacggtac ggggccgcag agcggcgccg acatcaaagt tgcgacttga
    11701 atcgcgaatg agaatagatt cgcattctcg gggcggtcaa gggttcgcgt tgccccggcg
    11761 ttaaccttgc gctccgatcg cgcttccatc ccggatcgcc agggttctcc cgccgccacc
    11821 tggccgactc cggcagccgg aggggcccct caccagcccc gtccggccac atcacccctt
    11881 gtcctgcgac acggatggat gcacactgtc tctcgcgaaa cgcgaaagct ttcgcatttt
    11941 ctaggtgggg cgggatgaac ccatggcccc caccacctga aggagcctgc gatgactcag
    12001 gacaatgtgc gcgtggacac cgcgtgggaa cgcgtcgacg ggcatgtgct cgatcagttc
    12061 cgcacccact ccgtggccaa cctcggcgac gccctcgacc ggctcaacat cgtcgacggg
    12121 ggcatcgccc ccatctggaa cggggccaag gccgtcggca cagcgcttcc ggtcctcacc
    12181 gtcgcgggcg acaacaaggc cgtgatcgcg gcgctcgaac acatccgccc cggtgacatc
    12241 ctcgtcatca acgccttcgg ctacgacggc cgcgccatca tcggcgacaa cctcgcccag
    12301 cggttcgccg cgtacggtgc cgcgggcgcg atcatcgacg gatacgtccg cgacgccgcg
    12361 atcatcgaag agctcggcat cccgatcttc gcccgcgggc tcactcccgc cggcccgttc
    12421 aagaacggac cgggcacgat cggcgaatcg gtcgccatcg gcggcgtcgt ggtgaacccc
    12481 ggcgacatca tcgccgccga cggggacggc gtcatcgtca ttccgccgcg ccgcgccgac
    12541 gaagcgctca agtcggtcag cgagatcgtc gcccgcgaag cggcactgga cgccgaggtc
    12601 gaagccctgc gaagcaagac cgccgcctcg taacgcccac ccccttaccg ctccacgggg
    12661 gccggcagga ggccatcggc gaccagcccg gcgagaacgg cctcgcccag ggcgtggacg
    12721 gcggactgtg gccggaccat gaccgtgaac tccttgatcc ggccgtcgtc gtcgaagtgc
    12781 agcagatcga tgccgtggat ctccttaccg cccacgacgg cccggaagag caggaccgcc
    12841 gaggcggaga cgccgccgtc ggcgctcgtc tccgcggtgc cgtcgtggtg gccgacgtag
    12901 cggaagttct caaaggtgcg cagcaggacc ccgaagaggc ccagcaccat gggcttgcct
    12961 tcgaaggggg tgaatttcac ggggctgtag aagcggatgt cgtccgtgaa caggtcctcc
    13021 agagctgcca ggtcgccgtt gtcgacggcg gcgcggaacc gtgcggctgc ggtcatgact
    13081 ctcacctcat actcatgaat atgactaatc agattgatga gtatgatgag gccgttccca
    13141 gggacaccgc aaggaggagg gcccgatggc gttgcggcac gcggttcttg cggcgctact
    13201 cgacgaggag ttgagcgggt accagctggt caaggcgttt gatctcggtg tggcgaactt
    13261 ctggcacgcg cagccgcagc aggtgtacgc ggagctggcg cggctggaga aggacgggct
    13321 gatcacgggc cgtgaagtgg tccaggacac ccgtcccaac aagcgtctgt tccaggtcac
    13381 cgacgccggt ctggccgagc tggaccactt cacggccacc gccgccaaac cgtccttcgt
    13441 gcgggacgac ttggtcgtca aggtccaggc cgccgatcac gtcgacaccc ggacgctgat
    13501 cgcgcgactg accgagcgcg cggcgctcgc ccaggccaag atcgacctgt tcggcaagct
    13561 tttgcgcggc atgcggggcg accgcaccga agaggagttc ctgcgccacg gcgagcgcat
    13621 cggcccctac ctcacctgcc tgcgcggcct ggccttcgag caaggcaacc tcgactggtg
    13681 cgagcgcacg gtcaccgtcc tccgggaaag agaaggtgcc gatgccccac gccgatgacc
    13741 cgcgggactg acctcgcgcc ccggcccggc ctggtcaccg acgtcgccgg gacttgcgcc
    13801 ggagccgcaa ggggatgacg taccagcaga tggcgaacca gagcatgacc aggccgacga
    13861 tcacctcggc gacaacgctg tcggtgacga cattgaggat gagcagcagg gtgcaggcga
    13921 tggtgagcgc cagcagcacc attccgcaca ccatgagccg gccggcagct tccacgacct
    13981 catccttcat gcgcagcccg gagagaaagc ggtggatcga aaccggggcg atcaaagcgg
    14041 cgaccgagga ggctcccaac gccaccgtca ccacataaag ggtgcggtcg aagacttcca
    14101 ggtccccgaa cgcgggcgtg aaggcgaggg agagcaggaa tccgaagagg atctgcacac
    14161 cggtctgcgc gaccctcgtc tcttgaagaa tctcgttcca tttccggttg acgcgctcgc
    14221 gggcagtctc cggccgttcg tgctcttcgg atgacggcgc gttcgtgcac gacgggcatg
    14281 atgagtcacg cactgccgca agatgcgggc ctgcaatcgt catgccgccg gggcctcgat
    14341 ctggtcgtgc agccgggcgc aggtccggtt gatcagccgg gagacgtgca tctgggagat
    14401 accgagttgt tcggcgatac ggccctgggt ctcctcgcgg aagaaacgca ggtagaggat
    14461 gtggcgctcg cgttcgggca gggcgcgcag ccgcggtttg agggcctcgc gctgaatgac
    14521 gcggtcgtag gagggctccg gtgcgccgag ggtgtcggcg agggagtatc cgtcctcggc
    14581 gcccggcagt tcggcgtcca gggacagcgc cgagaagctc tccatcgcct ccatccccag
    14641 cagcacatcc tcctcgctca tcccggtgtg ctcgacgatg gccgacacgc tcggggaacg
    14701 gtcatcggga gtgcgggtca gctcctgggc ggcggcgcgc acacggttac gcaactcctg
    14761 tacccggcgc ggcacatgca cgccccacat gtggtcccgg aagtggcgct tgatctcacc
    14821 cacgaccgtc ggcacggcga agctcgcgaa ggcggtgcca cggtccggct catagcgctt
    14881 gacggccttg accaggccga gcatcgccac ctgccgcaaa tcctccgcgg actcaccgcg
    14941 gttgcggaac tgccgggcca gccgctccgc catcggcatc caggcccgga cgacatcctg
    15001 ccgcagcgcc tccctctcgg gcccctcggg cagcgtggcg atgcgccgga actcggcgga
    15061 ggtgtcggga gcgtcgtcgt gcgagtgctt gctgcgtgtg cgtacggcag tcat
//
