LOCUS       reptomyces_RBGC_170294 16379 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_170294
VERSION     Streptomyces_RBGC_170294
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000720765.1
  ORGANISM  GCF_000720765.1
            .
FEATURES             Location/Qualifiers
     CDS             2..606
                     /protein_domains="PF00775"
                     /protein_domains="TIGR02423"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942734"
                     /pseudo=False
                     /translation="MTKIDTSRPETVLPTPSHTVGPFYGHALPFPGGGDIAPVGHPDTI
                     TVQGYVYDGEGNPLPDAFVELWGADPDGNIPQVDGSIRRDPASGGYLGRNGVEFTGWGR
                     IQTDANGHWYARTLRPGARGQSAPYLSVCVFARGLLVHLFTRIYLPGDEAALAADPVLS
                     QVPDGRRGTLIATDDGKGTYRFDIRLQGEGETVFLEFQ*"
     CDS             604..1940
                     /protein_domains="PF00206"
                     /protein_domains="PF10397"
                     /protein_domains="TIGR02426"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942735"
                     /pseudo=False
                     /translation="VTSVGFDDTGLLAPGWAGSPAASATGDAAFLQALLDAEAALTRAQ
                     SALDLAPSGAAAAVTEAADATRFDLRSLAERARAGGNPVIPLVADLTKAVGEEYGPYVH
                     RGATSQDIMDTATMLVAVRTLDLVLADLVRTERALARLAADHRDTAMPGRTLTQHAVPT
                     TFGLKAAGWRSLTLDARDRIKAVRDSLPIQLGGAAGTLAAFTVYGARDTQVLTAAYAHE
                     LGLREPLLPWHTLRTPIADLAGCLAFTAGALGKVAADVLALGRTEVAEVAEGSGGGSSA
                     MPHKANPVRSTLIAAAARRAPQLAATLYGSLAAEDERPAGAWHAEWEPLRDLLRLVGGA
                     ARDAAELAEGLRVHADVMREHLGLTHGLIVSERLSAELAPLLGRARAKALLTDLAERTY
                     TEGRPLAELLAEEPELKDLVDLDELTDPARYTGSAGVLTDRALERR*"
     CDS             1938..3058
                     /protein_domains="PF02627"
                     /protein_domains="PF00561"
                     /protein_domains="TIGR02427"
                     /protein_domains="TIGR02425"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942736"
                     /pseudo=False
                     /translation="LTEKLLNHRAEGPTSAPALLLGPSLGTSYALWDKVAPELSVTHRV
                     VRWDLPGHGGSAPGLIGPGATVGDLADLVLALADSLGIERFAYAGVSLGGAVGLHLGLH
                     HPERVSSLAVICSSAHFNGSKPWEERAELVRREGLGSLVASADARWFTPGFTVPELVRD
                     QAEADPEAYAACCDALAAFDLRDRLPEISVRTLLIAGREDKATPPPHLREIADAVSGSA
                     LVELPHAAHLAPAQCPEAVLTALRTHLGGAARRGMEVRREVLGDAHVDRAQARQTPFTA
                     RFQDFISRYAWGEIWTDPTLSRRERSMITLTALVAHGHYDELAMHVRAARRNGLTPEEI
                     GAVLLQTAVYCGVPAANSAFAAAQRVLAEEDGL*"
     CDS             3139..3929
                     /protein_domains="PF00106"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942737"
                     /pseudo=False
                     /translation="MSTILITGATSGLGRYVAFELVRSGHVVLAHGRDPGRTEQLVEEL
                     RAEGDAEGFVADLASLTQVHELGAHVADAHPDLDVLINNAGVGAGAPGAGRELSADGHE
                     LRLAVNYLAPVVLTRALLPVLRANTPARIVNVGSVGQDPLDFDDIEFRRQYDGFAAYRR
                     AKFALAAHTFALAEELADTGVSVNVLHPATFMDTAMVREGEVTPWNTVADGAPGVLALA
                     TQDLGTGGYYEGTSRARAHEATYDREIQKRLSTVTDQLLAL*"
     CDS             complement(4036..6719)
                     /protein_domains="PF13191"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942738"
                     /pseudo=False
                     /translation="MTEVRPMEAASASLWERDEEIAAVKQAIDTLCADRSSSGSVLVVR
                     GEAGLGKTALLAETRRIAERRNCTVWSTRGGETLRSVPFNVVRQLLQPALVSLMPEEAR
                     EYLGDWYDIAGPALGITEPGERQADPQGVCDGLVAGVRRLARRDWPLVLLIDDAHWADQ
                     ETLRWLAAFAERLDDLSVLVVVARRPGEVGGESARHLEAIAAASGHPDANLSALTPDAT
                     AGLTRATLGAHADAPFCREVWAVTGGNPYETVELLAKVQDSELEPTEGAAAELRALNRS
                     ARGGGLVARLEELGIDATRFAWAAAILGTGISVDLVAELATMDHDEALRCAELLQDARI
                     LTEPDPASAQADDGDLEFVHPLIATAVYNSIPDALRTAMHGIAAQVVTESGRGAAMASR
                     HLLQVHPDDDEELVEQLREAAREHLAVGAPDAARRCLERALLEPPLPEVHARVLYELGC
                     ATLLTAPATTIDHLQSALGMPGLDGDERVDAVFRLSQALLHNDQMEEAVRTVEAEAARH
                     AEGPAKMRLQAVQYMWESLYAGEATSQGRSQRLADLASTCTGRDNSERALLMLRGFDAL
                     IRGESAEEVVDLCDRALVNGRLAPGLGWTDTEWGIELLLMLGNSYTYTDRLDRAESLYN
                     EALRTYESAGWSGGHLALAHAHVGIGHRRRGRLREAEASLRESLRLAEPVGRGLPLYWC
                     VTCNLVEVLLARGHVDEAWAIADQYGFAPPYTSGVVMPDPRSVRGRLLLAVGRTKDGIN
                     ELEEAEKAVAARGHHNPVLVPWALDLARALASEDPARAARLVADTRRQAERFGTDTAIG
                     EALRCAAALETGQRAVRLLAQAVAYLEASPCQYEHAAARIEYGIAARSVTELNRGLALA
                     RSCGADGLMAKAREALEVGRGVR*"
     CDS             6742..6872
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MNDVQTSSVAVRLQKWRGVRVAVAVMGDSGCGQATHEACHLPV"
     CDS             6902..8181
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942739"
                     /pseudo=False
                     /translation="MTLLFGQRRAVPDSSAVRALAAGSVGNFVEWYEFGVYGYFATVIA
                     ARFFTPEGGSEAEALVRTYASFALAFFFRPVGAALFGRLGDRIGRRPVLILVIVVMTVA
                     TTLIGALPTYATVGALAPWLLTLLRAVQGLSAGGEFGGAVAVMTEFAPPGRRGLYGSWQ
                     SFTVALGLLGGAGVAALLATLLTQRQLGDWGWRVPFLLTLPLGLAALWLRLRLAETPEF
                     RRETEAVRLPPGEVAGAIALGAARIMGWAAAGYTFLVVLPSYLQSTLGAGFQQALIATV
                     LANLGFAVTIVPAGLLSDRLGRRAVMLTGALLVALLSLPLLNLLQDPGTSNTVKGAAVF
                     GAGAVVGLMAGPGPAMLSELFPTHVRHTGLGLAYALSNAVFSGCAGLIITETVKRTGSV
                     DIPGYYAAATCAVSVLALAKAPKRKAG*"
     CDS             8187..8389
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942740"
                     /pseudo=False
                     /translation="MRWTGLTPVEEVQDTLAAAPSPGITPPPEVTRRSTTIRQTHAVKT
                     RTPDILALTTTAQRKAGWTGCG*"
     CDS             8381..9534
                     /protein_domains="PF03702"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942741"
                     /pseudo=False
                     /translation="MRVIGLMSGTSYDAIDAAAADLRLDGDRLVLEPLGMVSEAYDEEL
                     REALAAALPPAATSLAEVCRLDTGIGQAFAAAAVRADRELCGGQAELVASHGQTVYHWT
                     DGGKVHGTLQLGQAAWIAEATGLPVVADFRPRDIAAGGQGAPLVDLIDLLWLRGRPGTP
                     VALNLGGIANLTAPDGTAFDTGPACALIDAAARGFSGGTMAYDVDGALAARGTVHEPLL
                     RRLLEEPYYALPAPKTTGKELFHLGYLRDALAGFGTLRAEDVVATLTMLTARTVADAVL
                     ALGTGEVIASGGGVRNPVLMGMLGQRLPGIPLRASDELGLASDAKEAYAFAVLGFLTAH
                     GLAGTEPASTGARHASVLGSITPGRDGLRLPPPGARAPKRLVVT*"
     CDS             9586..10640
                     /protein_domains="PF10708"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942742"
                     /pseudo=False
                     /translation="MTQVTPPGWYPDPGQTSEAPATERWWDGKAWTDRTRPAGSAAVWG
                     PPAQAPTAGADPADAAPPTVPAYAAYPDYPAYPAQPSAAPRRGLHTGIAVGAAVVVLAC
                     IGVGVYALAGNDGSGGNVNSQQGQGGTGGQGGPGGGQGGPGGGSSGSGGSGGSGGSGGS
                     QSPGPGLPEAPKIKSGSVSDPISGISLPIPDDWYGQQIAVGASITSNGSYKCPGDTSKT
                     CTKGGAYSAPAAVLKTAGSTAEEVAKADIKANAEESYGGKSYGSITSHKVLDSRAVTVA
                     GQKGYLVRWQAVTSKGSDGYVESLALPSPANPAQIVVVRFGVDVAEKQSVIDDITKGIK
                     VSTGGGNGQTV*"
     CDS             complement(10788..11401)
                     /protein_domains="PF16859"
                     /protein_domains="PF00440"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942743"
                     /pseudo=False
                     /translation="MTSQAADGPQTVAASRRSKITREREQEFFDAVLEQIRECGYEAVT
                     MEGVAASTRCSKSTLYRQWKTKPQFVVAALRSRRKARFEGIDTGSLADDLREAARAVGR
                     WSQNDTKLLQALGHAVTQDADLAKALREALVDPEIAALKEILRRGVERGEITAGHPALE
                     YIPAQMFGVVRARPVVDGEYADPEYLVRFVEAAVLPALGLT*"
     CDS             11632..12434
                     /protein_domains="PF14378"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942744"
                     /pseudo=False
                     /translation="MNARTEPAEGETDAIARPPVVREFLLVAGLFLVYKFGRQLATGHT
                     GEALRNAHRVWDLERTLHLPGEGSVQSLLLHSDTLVHLANTYYATVHFPATAAFLVWLY
                     LRRPAHYVWARRVLATVTSAALVLPFLFPLAPPRMLAATGLVDTAHVYGPSVYGPPSSD
                     HLSNQFAAMPSLHFGWALMVAVGLIAATRSRWRWLWLLHPLVTLLVIVGTANHYWLDAI
                     VATAMLGAALALVHRPHRTVTTAVRGGEKLAAPVADDHVLVGAGR*"
     CDS             12432..13396
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942745"
                     /pseudo=False
                     /translation="MTATLVAVALSLVSAVAYAAAAVAQERLASRSSGTGMLRLLGTGA
                     WWASVGLNAGAALLHVVALKYGPLTVVQPLGALTLVAAVPMGARAAGRRVSATEWRGTA
                     LTLAGLAALLVTASGSAPEQVLSLTEALAVAGTTAALIGLLSRPGARPGLRHATASGFA
                     SGVASALTQTVTVAATDRSGSALSFQVVLVAVLVAAFAVGGLLLSQTAYRGGLGAPLAM
                     VTLSNPVAASVIGLTLLGQGLRGGPEGILLALAGAALASWGVVLLTRATPAPVTPDAAV
                     PTVDEEHPVAAVLALKPESATPEPALVPRQSAAPGHLTPL*"
     CDS             complement(13416..14245)
                     /protein_domains="PF03803"
                     /protein_domains="PF10708"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942746"
                     /pseudo=False
                     /translation="VTTHSNTPAGWFPDPHGAPQTLRYWDGAQWTQHTSPDQGAQQAQA
                     AQQVPQQAAGPDPRVQRQVQQQAGVAARGPGGGSLFTEPVLVVNQKAKLIEVTNEYRVM
                     DQNGNQIGSVMEVGQSTLKKVARFVSSLDQFMTHRLEIRDAYGQPQLVLTRPAKVFKSK
                     VLVSRPDGSPVGEIVQENMIGKINFAMNVDGRKVGAIKAENWRAWNFAIVDHAENEVAR
                     ITKTWEGLAKTMFTTADNYVLQIHYQLPEPLLSLVVATALTVDTALKQDSRGLG*"
     CDS             complement(14323..16379)
                     /protein_domains="PF04185"
                     /protein_domains="PF05506"
                     /protein_domains="PF05506"
                     /protein_domains="TIGR03396"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_942747"
                     /pseudo=False
                     /translation="MPEVNRRRFLQLAGATTAFTALSNSIQRAAALPANHRTGSIEDVE
                     HIVVLMQENRSFDHYFGSLRGVRGFGDPRPVVTRQDGKPVWYQADANGKDILPFHPDAD
                     DLGLAFIQDLPHGWNDGHAAFNGGKYDKWVPSKGSTTMAYLTREDIPFHYALADSFTIC
                     DAYHCSFIGSTDPNRYYMWTGYTGNDGQGGGPVLGNDEAGYGWTTYPERLEKAGVSWKI
                     YQDVGDGLDANGSWGWIQDAYRGNYGDNSLLYFKQYQNAQPGSPLYDKARTGTDARKGE
                     GFFDQLKADVKGGKLPQISWIVAPEAFTEHPNWPANYGAWYVAQVLDALTSSPEVWAKT
                     ALFITYDENDGFFDHLVPPFAPGSAAQGKSTVDPALDLFKGNSSHPAGPYGLGQRVPMI
                     VVSPWSKGGYVCSETMDHTSIIRFMERRFGVHEPNVSPWRRAICGDLTSAFDFSRTDTK
                     PVALPGTDGYQPPDHNRHPDYVPTPPANPVLPKQERGLRPARPLKYAPYVDGSADMASG
                     KFTLTFASGAKAGAAFLVTSGNRTDGPWSYTTEAGKTVSDAWNSVYSNGSYDLAVHGPN
                     GFLRVFKGPNKVAGPEVTARHSGDDIELTFTNKGSGTVRLKLTGGYGCKPRTFTVRPGA
                     TVTHTVDLAASRRWYDLTVTSEADATFLRRFAGHVENGRPGVSDPAIITG*"
ORIGIN
        1 atgacgaaga tcgacacgag ccgtcctgag accgtgctcc cgaccccgtc gcacacggtc
       61 ggccccttct acggccacgc cctgcccttc cccggcggcg gcgacatcgc gccggtcggc
      121 cacccggaca cgatcaccgt ccaggggtac gtctacgacg gcgagggcaa cccgctgccg
      181 gacgccttcg tggagttgtg gggcgccgac cccgacggca acatccccca ggtcgacggt
      241 tcgatccggc gcgacccggc gagcggcggc tacctgggcc gcaacggcgt ggagttcacc
      301 ggctggggac gcatccagac ggacgccaac ggccactggt acgcgcggac gctgcggccc
      361 ggcgcgcgcg ggcagagtgc gccgtacctc agtgtgtgcg tgttcgcgcg cggactgctg
      421 gtgcacctgt tcacccggat ctatctgccg ggtgacgagg cggcgctcgc cgccgacccg
      481 gtgctgtccc aggtgccgga cggacgacgc ggcacgctga tcgcgacgga cgacggcaag
      541 ggcacatacc gtttcgacat ccgccttcag ggcgaaggtg agacggtctt cctggagttc
      601 cagtgacttc tgtcggcttt gacgacaccg gcctgctcgc ccccgggtgg gcaggctccc
      661 ccgccgcctc cgcgaccggc gacgcggcat ttctgcaggc cctgctcgac gcggaggccg
      721 ccctgacccg ggcccagtcc gctctggacc tcgcgccgtc cggggcggcg gccgcggtga
      781 ccgaggcggc cgacgccacc cgcttcgacc tacgctccct cgccgagcgg gcccgcgccg
      841 gcggcaaccc ggtcatcccc ctggtcgccg acctgacgaa ggcggtgggc gaggagtacg
      901 ggccgtacgt ccaccggggc gcgaccagcc aggacatcat ggacacggcg acgatgctgg
      961 tcgccgtgcg caccctggac ctggtcctcg ccgacctcgt ccgcaccgaa cgggcgctgg
     1021 cccggctggc cgcggaccac cgtgacaccg cgatgccggg acggacgctc acccagcacg
     1081 ccgtaccgac gacgttcggg ctgaaggcgg ccggctggcg gtcgctcacc ctcgacgcac
     1141 gggaccggat caaggccgta cgggattcac tgcccatcca actcggtggc gctgcaggca
     1201 cgttggcggc cttcaccgtg tacggcgccc gggacacgca ggtcctgacg gcggcctacg
     1261 cccacgaact cgggctgcgg gagccgctcc tgccctggca cactttgcgc acgccgatcg
     1321 ccgacctcgc cggatgcctg gccttcactg ccggggcgct gggcaaggtc gccgcggacg
     1381 tgctggccct cggccgcacc gaggtcgccg aggtcgcgga gggcagcggc ggcggttcgt
     1441 cggccatgcc gcacaaggcg aaccccgtac ggtccacgct gatcgcggcc gcggcccggc
     1501 gggctccgca gctcgcggcc acgctgtacg gatcgctggc cgccgaggac gagcgtccgg
     1561 ccggggcctg gcacgccgag tgggaaccgc tgcgggatct gctgcggctg gtcggcggtg
     1621 ccgcacggga cgccgccgaa ctggccgaag ggctgcgcgt gcacgcggac gtcatgcgtg
     1681 aacacctggg tctcacgcac ggtttgatcg tctcggaacg gctgtcagcc gaactggccc
     1741 ccctgctcgg ccgtgcccgc gccaaggccc tgctcaccga cctcgccgag cgcacgtaca
     1801 cggaaggccg cccgttggcc gaactgctcg ccgaggaacc ggagttgaag gacctcgtcg
     1861 acctcgacga gctcaccgat cccgcccgtt acaccggctc cgccggagtc ctcaccgacc
     1921 gtgccctgga gcgacgttga ccgagaaact cctcaaccac cgtgccgagg ggcccacttc
     1981 cgctcccgcg ctgctgctcg ggccctcgct cgggacgtcg tacgcactgt gggacaaggt
     2041 ggcacccgag ctgtccgtca cccaccgggt cgtccgctgg gacctgccgg ggcacggcgg
     2101 ttcggcgccc ggcctgatcg gtcccggcgc gaccgtcggt gacctcgccg atctggtgct
     2161 ggccctcgcc gactcgctgg gcatcgagcg gttcgcgtat gcgggggtgt cgctcggcgg
     2221 tgccgtcgga ctgcatctgg gcctgcacca cccggagcgg gtgtcgtcgc tggccgtcat
     2281 ctgttcgtcg gcgcacttca acggctccaa gccgtgggag gagcgggccg agctggtgcg
     2341 gcgcgagggg ctgggctcgc tggtggcgag cgccgatgcc cggtggttca cgcccgggtt
     2401 caccgtgccg gaactggtgc gggaccaggc agaagccgac cccgaggcgt acgccgcctg
     2461 ctgtgacgcg ctggccgcct tcgacctgcg cgaccggctc ccggagatct ccgtgcgcac
     2521 gctgctgatc gccgggcgcg aggacaaggc gaccccgccg ccgcatctgc gggagatcgc
     2581 ggacgccgtg tccggctccg cgctggtcga gctcccgcac gccgcgcatc tggcgcccgc
     2641 ccagtgcccg gaagccgtgc tgacagccct gcggacccac ctcggcggag ctgccaggcg
     2701 cggcatggag gtacggcggg aggtgctcgg cgatgcgcac gtggaccggg cccaggcccg
     2761 gcagacgccc ttcaccgccc gcttccagga cttcatctcg cgctacgcct ggggcgagat
     2821 ctggaccgac ccgacgctca gccgccgcga acgcagcatg atcacactga cggcactggt
     2881 cgcacacggg cactacgacg agctggccat gcacgtacgg gcagcccgcc gcaacgggct
     2941 cacccccgag gagatcggcg ccgtactgct gcagacggcc gtgtactgcg gggtcccggc
     3001 agcgaactcg gcgttcgcgg cggcccagcg ggtgctggcg gaggaggacg gcctctgaag
     3061 cctctgaagg tgaccctgcc ggtcgtagct tcagcagcat ctcgcacatg cctccaccgc
     3121 gtgcctacgg tggaggcatg tccaccatcc tgatcaccgg cgccacctcc ggcctcgggc
     3181 gctacgtcgc cttcgagctt gtccgctcgg gacacgtcgt cctcgctcac ggccgcgatc
     3241 cgggccgtac ggagcagctg gtcgaggagc tgcgcgccga gggcgacgcg gaaggcttcg
     3301 tcgccgacct cgcctcactg acgcaggtgc acgagctggg cgcccacgtc gccgacgccc
     3361 accccgacct cgatgtcctg atcaacaacg ccggtgtggg agcgggcgcg cccggcgcgg
     3421 ggcgtgagct gagcgccgac gggcacgaac tgcggctcgc cgtgaactac ttggcaccgg
     3481 tcgtactcac ccgcgccctg ctcccggtgc tgcgcgcgaa cacacccgcc cggatcgtca
     3541 acgtcggctc ggtcggccag gaccccctcg acttcgacga catcgaattc aggcgccagt
     3601 acgacggctt cgccgcctac cgccgcgcca agttcgccct ggcggcccac accttcgccc
     3661 tcgccgagga gctggcggac acgggcgtct cggtgaacgt cctgcacccg gccaccttca
     3721 tggacacggc catggtccgc gagggcgagg tcaccccttg gaacacggtg gccgacgggg
     3781 cacctggtgt gctggccctg gcgactcagg acttgggcac aggcggctat tacgagggga
     3841 ccagccgagc aagggcgcac gaggcaacgt acgaccgcga gatacagaaa cgtctgtcga
     3901 cagtcactga tcaactgctt gcgctgtagc gcccttcagg gacgcggggc tgtgtcggta
     3961 tgcggctccg ccgcgtgggc gcgatcaacc acggacaacc cgcagccgcc gtacaacctt
     4021 gcgccccgag ctcttcagcg caccccgcgc ccaacctcca gcgcctcccg agccttcgcc
     4081 atcaacccat ccgccccgca cgaccgagcc aacgccaacc cccggttcag ctcggtaaca
     4141 gacctcgcag cgatcccgta ctcgatacgg gccgccgcat gctcgtactg gcagggcgaa
     4201 gcctccagat acgccacagc ctgcgccagc agccggacag cccgctgccc ggtctccagc
     4261 gctgcagcgc accgcagagc ctccccgatg gcggtgtccg tgccgaaccg ctcggcctgc
     4321 cggcgggtgt ccgcgacgag ccgagccgca cgggccgggt cctcggaggc gagggcccgg
     4381 gcgagatcga gcgcccaggg gacgagcacc gggttgtggt gaccgcgtgc ggccacggcc
     4441 ttctcggcct cctccagttc gttgatgccg tccttggtgc ggccgacggc gagcagcagc
     4501 cgaccgcgca cggaccgcgg atccggcatc accacgccgg aggtgtacgg cggtgcgaag
     4561 ccgtactggt cggcgatcgc ccaggcctcg tcgacatggc cacgggcgag caggacctct
     4621 acgaggttgc aggtgacgca ccagtacagg ggcagtccgc ggccgacggg ttcggcgagg
     4681 cgcagggact cgcgcaggga ggcctcggcc tcccgcaggc ggccgcgcct gcggtgtccg
     4741 atgccgacgt gggcgtgggc cagggcgagg tggccgccgc tccagccggc cgactcgtaa
     4801 gtgcgcaggg cctcgttgta gaggctttcc gcacggtcga ggcggtcggt gtaggtgtag
     4861 gagttgccga gcatcagcag gagttcgatg ccccactcgg tgtcggtcca gccgagtccg
     4921 ggtgcgaggc ggccgttgac gagggcgcgg tcgcacaggt cgacgacctc ctcggcgctc
     4981 tcaccgcgga tcagggcgtc gaagccgcgc agcatgagca gggcgcgttc ggagttgtcg
     5041 cggccggtgc aggtcgaggc gaggtcggcg aggcgctggg agcgcccctg cgaggtcgcc
     5101 tcgccggcat aaaggctctc ccacatgtac tgcacggcct gcagccgcat cttcgccggc
     5161 ccctccgcgt gccgggcggc ctccgcctcg accgtgcgga ccgcctcctc catctggtcg
     5221 ttgtggagga gcgcctggga gaggcggaag acggcgtcga cgcgctcgtc gccgtcgagg
     5281 cccggcatgc cgagcgcgga ctgcaggtga tcgatggtgg tggcgggcgc ggtgaggagg
     5341 gtggcgcagc cgagttcgta gagcacgcgc gcgtggacct cgggaagggg cggttccagc
     5401 agggcgcgct ccaggcagcg gcgggccgcg tcgggggcgc cgacggcgag gtgttcgcgg
     5461 gctgcctcac gcagctgctc gacgagttcc tcgtcgtcgt ccgggtgcac ctggaggagg
     5521 tgccgggagg ccatggcggc gccgcgtccg gactccgtga cgacctgggc ggcgatgccg
     5581 tgcatggcgg tgcgcagggc gtccgggatg gagttgtaga cggcggtggc gatcagcggg
     5641 tgcacgaact ccaggtcgcc gtcgtcggcc tgggcgctcg ccgggtcggg ttcggtgagg
     5701 atgcgggcgt cctgcagcag ttcggcgcag cgcagtgcct cgtcgtggtc catggtggcg
     5761 agctcggcca ccaggtcgac cgagatgccg gtgccgagga tggcggcagc ccaggcgaag
     5821 cgggtggcgt cgatgccgag ttcctcgagg cgggcgacga ggccgccgcc gcgggccgag
     5881 cggttgaggg cgcgcagttc ggcggccgcg ccctcggtcg gctccagctc gctgtcctgg
     5941 accttggcga ggagttccac ggtctcgtac gggttgccgc cggtgacggc ccagacctcg
     6001 cggcagaacg gggcgtcggc gtgcgcgccg agggtggcgc gggtgaggcc ggcggtggcg
     6061 tccggggtga gggcgctcag gttggcgtcg ggatggcccg aggcggcggc gatcgcttcg
     6121 aggtgacggg cgctctcgcc gccgacctcg ccgggccgac gggccacgac gaccaggacg
     6181 gacaggtcgt cgagacgctc ggcgaacgcg gcgagccagc gcagcgtctc ctggtcggcc
     6241 cagtgcgcgt cgtcgatcag caggaccagc ggccagtccc ggcgggccag ccggcgcacc
     6301 ccggcgacca gtccgtcgca cacgccctgc gggtcggcct ggcgctcgcc cggttccgtg
     6361 atgccgaggg cggggcctgc gatgtcgtac cagtcgccga ggtattcgcg ggcctcctcc
     6421 ggcatcaggg acaccagcgc gggctgcagc aactgccgta ccacgttgaa gggaacggat
     6481 ctgagggtct cgccgccgcg ggtcgaccac accgtgcagt tgcgccgctc cgcgatgcgg
     6541 cgggtctcgg ccagcagggc ggtcttgccg agccccgcct cgccccggac caccagcacg
     6601 ctgcccgagg acgagcggtc ggcgcacagc gtgtcgatcg cctgcttgac ggcggcgatc
     6661 tcctcgtcgc gctcccacag ggaggccgag gcggcctcca tgggccggac ctccgtcatc
     6721 ccgctacctc cccaagtcgc ctgaacgacg tacagacatc gagcgtagcc gtccgattgc
     6781 agaagtggag gggggtccgg gtagctgttg ccgttatggg tgacagcggg tgcgggcagg
     6841 cgacgcatga agcctgtcat ctgcctgtgt gaaggtaacc gacagtcaaa aggcgctgaa
     6901 atgacgctgc ttttcggaca acgccgggcc gtgccggact cgtctgcggt acgggcgctg
     6961 gcggccgggt cggtgggcaa cttcgtcgag tggtacgagt tcggggtcta cggctacttc
     7021 gcgaccgtga tcgcggcgcg gttcttcacc ccggagggcg gcagcgaggc cgaggcgctg
     7081 gtgaggacgt atgcgtcgtt cgcgctggcg ttcttcttcc ggccggtcgg ggctgccttg
     7141 ttcgggcggc tgggggaccg gatcgggcgg cgtccggtgc tgatcctggt gatcgtggtg
     7201 atgacggtcg cgacgacgct gatcggtgcg ctgccgacgt atgcgaccgt cggggctctt
     7261 gctccgtggc tgctgactct tctgagggcg gttcagggac tgtctgcggg tggggagttc
     7321 ggtggggcgg tggcggtgat gacggagttc gctccgccgg ggcggcgtgg gctgtacggg
     7381 tcgtggcagt cgttcacggt ggcgctgggg ctgttgggcg gggcgggggt ggcggcactg
     7441 ttggcgactc tgctcaccca gcggcagctg ggcgactggg ggtggcgggt gccgttcctg
     7501 ctgacgctgc cgctcgggct ggcggcgctg tggctgaggc tgcggctggc ggagacgccg
     7561 gagttccggc gggagaccga ggccgtgagg cttcctccgg gcgaggtcgc cggcgccatc
     7621 gcgctgggcg cggcacggat catgggctgg gcggcggcgg ggtacacctt cctggtcgtc
     7681 ctgccgtcgt atctgcagag cacgctgggc gcaggcttcc aacaggcgct gatcgcaacc
     7741 gtgttggcca acctgggctt cgcggtcacg atcgtcccgg caggtctgct cagcgaccgg
     7801 ttggggcggc gagcggtgat gctgacgggc gcgctgctcg tggcgctcct gtccctgcca
     7861 ctgctcaacc tcctgcagga cccgggaact tcgaacaccg ttaagggtgc ggcggtgttc
     7921 ggggcgggtg cggtggtcgg cctgatggca gggccgggac cggcgatgct ctcggaactc
     7981 ttccccacgc acgtgcgcca cacgggcctg ggactcgcct acgccctctc gaatgccgtg
     8041 ttctccggct gtgccgggct catcattacg gaaaccgtca agcggacagg gagcgtcgac
     8101 atccccgggt actacgcggc ggcgacgtgt gcggtgagcg tcctcgccct ggccaaggca
     8161 ccgaaacgga aggcgggttg agcagatgcg gtggacaggc ctgacgccag tggaggaggt
     8221 gcaggacacg ctcgcagccg caccgtcgcc gggcatcacc ccgccaccgg aagtcacccg
     8281 ccgcagcacg acgatccggc agacccacgc ggtgaaaacc cgcacgccag acatcctcgc
     8341 cctcaccacg acagcgcaac ggaaggcagg gtggaccgga tgcgggtgat cggcctgatg
     8401 tcgggcacgt cctacgacgc catcgacgcg gcggcggccg acctgaggct cgacggcgac
     8461 cgcctcgtac tggagccgct ggggatggtg agcgaggcgt acgacgagga gctgcgggag
     8521 gcgctcgcgg ccgcgctgcc gccggctgcg acgtcgctgg cggaggtgtg ccggctcgac
     8581 acggggatcg ggcaggcctt cgcggcggcg gccgtgcggg cggatcgtga actgtgcggc
     8641 gggcaggccg agttggttgc ctcgcacggg cagaccgtct accactggac ggacggcggc
     8701 aaggtgcacg gcaccctgca gctcgggcag gccgcctgga tcgcggaggc gaccgggctg
     8761 ccggtggtgg ccgacttccg gccgcgggac atcgccgcgg gcggccaggg cgcgcccctg
     8821 gtggacctga tcgacctgct gtggctgcgc ggccgtccgg gcacgccggt cgccctcaac
     8881 ctcggcggca tcgccaacct caccgccccc gacggcaccg ccttcgacac cgggcccgcg
     8941 tgtgcgctga tcgacgcggc ggcccggggg ttcagcggcg ggaccatggc ctacgacgtc
     9001 gacggtgcgc tggccgcccg cggcaccgtc cacgagcccc tgctgcggcg gctgctggag
     9061 gagccgtact acgcgctgcc cgcgcccaag acgacgggca aggaactgtt ccacctcggc
     9121 tatctgcggg acgcgctggc cgggttcggg acgctgcggg ccgaggacgt ggtcgccacg
     9181 ctgaccatgc tcacggcgcg gacggtcgcg gacgccgtgc tcgccctggg caccggcgag
     9241 gtgatcgcct cgggcggcgg ggtccgcaac ccggtgctca tggggatgct ggggcagcgg
     9301 ctgccgggga ttccgttgcg cgcctccgac gagctggggc tggcgtcgga tgcgaaggag
     9361 gcgtacgcgt tcgccgtgct cgggttcctg accgcgcacg gtctggcggg caccgagccc
     9421 gcgagcaccg gggcgcggca tgcgagcgtg ctcggctcga tcacacccgg ccgggacgga
     9481 ctgcggctgc cgccaccggg ggcgcgggcg ccgaaacggc tggtggtgac ctgaagccgg
     9541 attcctctca tgccgctttc accgaggcct catacggtgg gggcatgacg caggtgactc
     9601 ctcccgggtg gtatcccgac cccgggcaga caagtgaggc tcccgccacc gagcgctggt
     9661 gggacggcaa ggcatggacg gaccggaccc gccccgcggg gtcggccgcc gtatggggtc
     9721 ccccggcgca ggcgccgacg gccggggcgg atccggcgga cgctgcccct ccgacggtcc
     9781 cggcctatgc ggcatacccg gactatccgg cctatcccgc ccagccgtcg gccgctccgc
     9841 ggcgcggcct gcacacgggc atcgccgtcg gagccgccgt ggtcgtcctc gcgtgcatcg
     9901 gtgtgggtgt gtacgcgctg gcgggcaacg acggttcggg cggcaacgtc aactcgcagc
     9961 aggggcaggg cggcaccggc ggccaagggg ggccaggcgg cggtcagggc ggtccgggcg
    10021 gggggtccag tggctccggt ggctccgggg gttcaggtgg ctcgggcgga tcccagtcgc
    10081 ccggccccgg cctgcccgag gctccgaaga tcaagagcgg ttcggtgtcc gacccgatca
    10141 gcgggatcag tctgcccatc ccggacgact ggtacggcca gcagatcgcg gtgggcgcgt
    10201 cgatcacgtc caacggctcc tacaaatgcc ccggggacac ctccaagacc tgcacgaagg
    10261 gcggcgcgta ctcggcgccg gccgcggtcc tcaagaccgc gggcagcacg gccgaggagg
    10321 tggcgaaggc cgacatcaag gccaacgccg aggagtccta cggcggcaag agctacggct
    10381 cgatcacctc gcacaaggtg ctggactcca gggcggtcac cgtggccggg cagaagggct
    10441 acctggtccg ctggcaggcg gtcaccagca agggctccga cggctacgtc gagtcgctcg
    10501 ccctcccctc ccccgcgaac ccggcgcaga tcgtcgtggt ccgcttcggc gtggacgtcg
    10561 ccgagaagca gtcggtcatc gacgacatca ccaagggcat caaggtgtcg accggcggcg
    10621 gcaacggcca gacggtgtga accaccccgg acaccgatcg gccgggtggg gcgcccctcc
    10681 gctcaagagg agccccaccc ggccgggggg tgcgcgccgc ccccgtcccc acggtgcggc
    10741 gcgagcaggt caccgtccag tcatcccacg gacggcgacc tgattctcag gtgaggccca
    10801 gtgccggcag caccgcggcc tccacgaagc ggaccaggta ctcggggtcg gcgtactcgc
    10861 cgtccacgac gggccgggcg cgtacgacgc cgaacatctg cgccgggatg tactccagcg
    10921 ccggatggcc ggcggtgatc tcgccgcgct cgaccccgcg tctgaggatc tccttcagcg
    10981 cggcgatctc cgggtcgacg agcgcctccc gcagcgcctt ggcgaggtcg gcgtcctggg
    11041 tgacggcgtg cccgagggcc tgcagcagct tggtgtcgtt ctgcgaccag cggcccacgg
    11101 cccgcgcggc ctcgcgcagg tcgtccgcga gtgatccggt gtcgatgccc tcgaagcggg
    11161 ccttgcggcg ggagcgcagg gcggccacca cgaactgggg cttcgtcttc cactgccggt
    11221 acagcgtgga cttgctgcag cgcgtgctgg cggcgacccc ctccatggtg acggcttcgt
    11281 atccgcattc gcggatctgc tcaaggacgg cgtcgaagaa ctcctgctca cgctcgcgcg
    11341 tgatcttgga gcggcgcgag gcggcgaccg tctgcggtcc gtccgcggcc tgcgacgtca
    11401 tctgcttttc tccctcactc cgagtgccgg ctttattcgc gctttattcc cggcttccag
    11461 tgtgtcgtac ctcaatcgat acgccagtgt accggaacgg ccgcgtatcg gtacactgcc
    11521 gtatcggaac gctttcgttt cggcacgcaa gcgtaccgat gagttcgggc tccggcccgg
    11581 gtctcaccac gtaccagcac acgcaccacc gtcagcgaag gggccggggg atgaatgccc
    11641 gcaccgagcc tgcagaagga gagaccgacg cgatagcgcg gcctccggtc gtccgtgagt
    11701 tcctgctcgt cgcagggctc ttcctcgtct acaagttcgg ccgtcagctg gcgaccggcc
    11761 acaccggcga agccctgcgc aacgcgcacc gcgtgtggga cctggaacgg acgctccatc
    11821 tgcccggtga gggctcggtg cagtccctac tgctgcacag cgacaccctg gtgcacctcg
    11881 cgaacaccta ctacgcgacc gtccacttcc cggccaccgc ggccttcctg gtctggctct
    11941 atctgcggcg ccccgcgcac tacgtgtggg cccgccgggt cctcgccacg gtcacctccg
    12001 cggccctggt gctgcccttc ctgttcccgc tcgcaccgcc gcggatgctg gccgccacag
    12061 gcctcgtcga cacggcgcac gtgtacgggc cgtcggtcta cggccccccg tcctcggacc
    12121 acctctccaa ccagttcgcg gcgatgccgt cactgcactt cggctgggcc ctgatggtcg
    12181 ccgtcggcct gatcgcggcg acccggtccc gctggcgctg gctgtggctg ctgcacccgc
    12241 tggtgacgct gctggtcatc gtgggcacgg cgaaccacta ctggctcgac gcgatcgtcg
    12301 cgaccgccat gctcggcgcc gcgctggcgc tggtacaccg gccacaccgc acggtcacca
    12361 cggccgtgcg cggcggcgag aagctcgccg cccccgtcgc cgacgaccac gtcctcgtag
    12421 gagcgggccg atgaccgcca cactcgtcgc cgtcgccctg tcgctggtct ccgccgtcgc
    12481 ctatgcggcc gccgccgtgg cccaggagcg gctcgcctcc cgcagctccg gcaccggcat
    12541 gctgcggttg ctgggcacgg gcgcctggtg ggcgtcggtc gggctcaacg ccggcgcggc
    12601 cctgctgcac gtcgtggccc tcaagtacgg cccgctcacc gtcgtccagc cgctcggcgc
    12661 gctcacgctg gtcgccgcgg tgccgatggg ggcacgggcg gccgggcggc gggtcagcgc
    12721 gaccgagtgg cggggcaccg cgctgacgct ggccgggctg gccgcgctgc tggtcaccgc
    12781 gtccgggtcg gcgcccgagc aggtgctgag cctgaccgag gcactggcgg tcgcgggcac
    12841 cacggccgcg ctgatcgggc tgctctcacg gccgggcgcc cggccgggcc tgcggcacgc
    12901 cacggcgtcc gggttcgcct cgggcgtcgc gtcggcactc acgcagaccg tgacggtcgc
    12961 cgcgaccgac cggtccggct ccgcactgag cttccaggtc gtcctggtgg ccgtactggt
    13021 ggccgccttc gcagtcggcg gactgctgct gtcccagacg gcgtaccggg gtgggctcgg
    13081 cgcccccctc gccatggtga cgctctccaa cccggtggca gcctcggtga tcggcctcac
    13141 cctgctcggc cagggcctgc gcggcgggcc ggagggcatc ctgctcgccc tcgcgggtgc
    13201 ggcacttgcg tcatggggtg tcgtactgct gacccgggcg acacccgctc cggtcactcc
    13261 ggatgctgcg gtgccaacgg tcgacgagga gcaccccgtg gccgcggtcc tggccctgaa
    13321 gccggaaagc gccacgccgg aaccggcttt ggtgcccagg cagtccgccg cgccggggca
    13381 cctcacacca ctgtgaacgc cactcggagc agcgtcagcc gagacctcgc gagtcctgct
    13441 tgagcgccgt gtccacggtg agtgccgtcg cgacgacaag gctcaacagc ggctcgggca
    13501 gctggtagtg gatctgcagg acgtagttgt ccgcggtggt gaacatcgtc ttggcaaggc
    13561 cctcccaggt cttggtgatc cgggcgacct cgttctccgc gtggtcgacg atggcgaagt
    13621 tccaggcccg ccagttctcc gccttgatcg caccgacctt ccggccgtcc acgttcatcg
    13681 cgaagttgat cttcccgatc atgttctcct ggactatctc gcccaccggc gagccgtccg
    13741 gacgggacac cagaaccttg gacttgaaga ccttggcggg ccgcgtcagc accagctgcg
    13801 gctgaccgta ggcgtcccgg atctccagcc ggtgggtcat gaactggtcg aggctggaga
    13861 cgaagcgcgc gaccttcttc agcgtgctct gcccgacctc catcaccgag ccgatctggt
    13921 tgccgttctg atccatgacc ctgtactcgt tggtcacctc gatcagcttg gccttctggt
    13981 tgaccaccag gaccggctcg gtgaacaggc tgccgccgcc ggggccgcgg gcggcgaccc
    14041 cggcctgctg ctggacctga cgctgcacac gcgggtccgg cccggcggcc tgctgcggta
    14101 cctgctgggc ggcctgggcc tgttgggcgc cctggtccgg gctggtgtgc tgggtccact
    14161 gggcgccgtc ccagtagcgg agggtctggg gcgctccgtg cggatccggg aaccagcctg
    14221 caggagtgtt cgaatgcgtg gtcaccgggg cacactaccc cgggcccacc ggctcctggc
    14281 cagtccccgc gatccgctgt caccagcctt tacccgacag ttcagccggt gatgatcgcc
    14341 gggtcgctca cccccgggcg cccgttctcg acatgtccgg cgaaccgccg caggaacgtc
    14401 gcgtccgcct cggacgtcac ggtgaggtcg taccagcgtc ggctcgccgc aaggtcgacg
    14461 gtgtgcgtca ccgtggctcc gggccgcacc gtgaaggtcc ggggcttgca gccgtatcca
    14521 cccgtcagct tcagacggac cgtgccggag cccttgttgg tgaaggtcag ctcgatgtcg
    14581 tcgccgctgt ggcgggcggt gacctcgggc cctgccacct tgttcggccc cttgaagacg
    14641 cgcaggaaac cgttcgggcc gtgcacggcc aggtcgtacg agccgttcga gtacaccgag
    14701 ttccaggcgt ccgagacggt cttgccggcc tcggtggtgt agctccaggg cccgtcggtg
    14761 cggttgccgg aggtcaccag gaaggcggcg cccgccttgg ctcccgaggc gaaggtcagg
    14821 gtgaacttcc cggaggccat gtccgccgaa ccgtccacgt acggggcgta cttgagggga
    14881 cgcgccggac gcaggccgcg ctcctgcttg ggcaggaccg ggttggcggg cggggtcggc
    14941 acatagtcgg ggtgacggtt gtgatccggc ggctggtagc cgtcggtgcc cgggagggcg
    15001 accggcttgg tatcggtgcg ggagaagtcg aacgcggagg tcagatcgcc gcagatcgcc
    15061 cgacgccagg gcgagacgtt cggctcgtgc acaccgaagc gacgctccat gaaccggatg
    15121 atcgaagtgt ggtccatcgt ctcggagcag acgtaaccgc ccttgctcca gggcgagacg
    15181 acgatcatcg gcacgcgctg gccgagcccg taggggcctg cggggtggct gctgttgccc
    15241 ttgaacaggt cgagggcggg gtccaccgtg gacttgccct gcgccgcgga gcccggtgcg
    15301 aacggcggga ccaggtggtc gaagaagccg tcgttctcgt cgtacgtgat gaacagggct
    15361 gtcttcgccc acacctcggg cgaggaggtg agcgcgtcga ggacctgggc gacgtaccag
    15421 gcgccgtagt tggcgggcca gttggggtgt tcggtgaagg cctccggggc gacgatccag
    15481 gagatctgcg gcagcttgcc gcccttcacg tccgccttca gctggtcgaa gaagccctcg
    15541 cccttgcggg cgtcggtccc ggtgcgggcc ttgtcgtaga gcgggctgcc gggctgcgcg
    15601 ttctggtact gcttgaagta gagcagcgag ttgtcgccgt agttgccgcg gtaggcgtcc
    15661 tggatccagc cccaggaacc gttcgcgtcg agaccgtcgc cgacgtcctg gtagatcttc
    15721 caggagacgc cggccttctc caggcgctcg gggtaggtgg tccagccgta gccggcctcg
    15781 tcgttgccga ggaccgggcc gccgccctgg ccgtcgttgc ccgtgtaacc ggtccacatg
    15841 tagtagcggt tcgggtcggt cgagccgatg aacgagcagt ggtacgcgtc gcagatggtg
    15901 aaggagtcgg cgagcgcgta gtggaacggg atgtcctcgc gggtcaggta cgccatcgtc
    15961 gtggacccct tggagggaac ccacttgtcg tacttgcccc cgttgaaggc ggcatgtccg
    16021 tcgttccagc cgtgcgggag gtcctggatg aaggccaggc ccaggtcgtc ggcgtccggg
    16081 tggaagggca ggatgtcctt gccgttcgcg tcggcctggt accagaccgg cttcccgtcc
    16141 tgccgggtca ccacgggacg ggggtcaccg aagccgcgaa cgcctctgag cgagccgaag
    16201 tagtggtcga aggaacggtt ctcctgcatc aggacgacga tgtgctcgac gtcctcgatg
    16261 gatcccgtgc ggtggttcgc gggcagcgcg gcggcgcgct ggatgctgtt ggacagggcg
    16321 gtgaaggcgg tggtcgcgcc cgcgagttgc aggaatcggc gccggttgac ttcgggcat
//
