LOCUS       reptomyces_RBGC_175963 16485 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_175963
VERSION     Streptomyces_RBGC_175963
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_003687505.1
  ORGANISM  GCF_003687505.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..726)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834504"
                     /pseudo=False
                     /translation="VAADGSDRGRANVTRSTTTPVRKALTSLDHRVELAVGYTVDRLWR
                     DHDRGLLDEQTESVAAAHRSLSSAEQSVTFYRVLLQRLASGEYPMDSALFDRIGRTVKQ
                     LQEAVRIRGVRETELSDVLEPVEANAARTPAGHADLKAHDIALLLAIGQGAKLREHLLT
                     QRLSVVTASGTRIGQHDFARLETAGLVDRDTSHPLHAGQPVALTDAGRAALAARPSSRV
                     TSRPAPRPGAWPDAATRTR*"
     CDS             complement(708..1090)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834505"
                     /pseudo=False
                     /translation="LTAFPNFLDHFGENLLELPAEPENPHHRALLETYIEVQQLERRLL
                     ETLTKPHPDITPDGFHACTEILIDRIAAGQELAVLLSAPCCCAPAEESSCEKDPDNCSP
                     DCYEAVDHAGDEDAAGRRGCRRQ*"
     CDS             complement(1088..1566)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834506"
                     /pseudo=False
                     /translation="VSAEGRPPAFGLTFDPRALTDLLQAPSDIRDLSLALLQEVVNADR
                     HGGKLTAELAGLRKLYVDRQAAWRIVYALRPAPQTSAYPMEIHVVAVRPRANHDIYDTV
                     ARRLGIDHRPVGARAHAARTRSPQIDAYREIPKPGPPPGLPRSAQPTVLTTKAVR*"
     CDS             complement(1564..2189)
                     /protein_domains="PF16259"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834507"
                     /pseudo=False
                     /translation="LEPDPLEEFGAAGEFDPVRLPEGDLDSIQATVRKLLDRSAEQARQ
                     LDHLAAAPGPVSLPGFGLPPMPSAAMMPPEPRPILELDGEEYESELDLLTDWVEDFLMP
                     TYGSEVTTASPWCDQWQEHLDVVAWLHALWMAYLQHKDPEAGPAGPFVWHRDFLTHCMA
                     AIRAAGGPLSACQTDPERPSHRLLRGPGRSVRAVARDAETAQAEE*"
     CDS             complement(2317..3071)
                     /protein_domains="PF01555"
                     /protein_domains="PF01555"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834508"
                     /pseudo=False
                     /translation="LPFSLHHGDALGVLAGLPDDCVDAVITDPPYNSGGRTAKERTSRT
                     ARQKYTSADAGHELADFPGENMDQRSYGFWLTQIMTEAHRLTKPGGAALLFTDWRQLPV
                     TTDAIQAAGWLWRGVLAWHKPQARPQKGRFKQSCEFIVWASNGAIDGSRNPVYLPGLYS
                     ASQPSGKARQHITQKPVEVMRELVKISPPGGTVLDFTCGSGSTGVAALLEGRDFIGVEK
                     TRHYAEIASDRLTETLHQTLGQDDLTLTS*"
     CDS             3578..4701
                     /protein_domains="PF00877"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834509"
                     /pseudo=False
                     /translation="LKGIAAAVGVVVLSPLLLAGAAATAAAASSSASRATQCGVDNTVD
                     ANAVAQQVAGILGGSGATPGIQIKGLELPAEQIPHAKTIIATGIAMKVPERGQVVALAT
                     AIQESRLRNLRYGDRDSLGLFQQRPSMGWGTAEEILDPVHASTRFYEGLLKVAGWQQMT
                     ITQAAQAVQISGYPDAYAQWESLARALQEAIVKTLPQGGGDTGAPGGPAGGGCRPGEDG
                     SQWGEIPQGTVPAGYKIPADASPKARTAIEWAMHQLGTPYQWGGTCKDSHGPDPMGRCD
                     CSSLMQVAYAKAGVTLTRTTYTQVKEGVPVPVTALKPGDLLFTRGTAAVPEHVGMYMGA
                     GLVINAPKTGRPVRIEKVADWQILAVRRIPALSS*"
     CDS             4964..5160
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_4834510"
                     /pseudo=False
                     /translation="MAAIIAVVGALAVSLGVWAWGHHTGGHQAEANGKKGALVSAGAAL
                     GLGAANGIIAFFSTLGTQVR*"
     CDS             5161..5849
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834511"
                     /pseudo=False
                     /translation="MGKRSRPRVRAATAHWSTGRRVAVLAAVLALLLAGAGLAAYLTTG
                     GGRGKAPSGKPSVSNPTARPGTSAPVAEAATGTVSPPPRLSDPLAYGRAAAVMLWSYDT
                     RATTRDQQLAGMHAWMTTETKYTDWTSIQAQVPDPLLWSRMHDQGQHATATVSQSHFPS
                     AFKQALAENPAALTEAYIYAVTVTGKQAIAWKDGGGGAEDRSVTLAVQCRPSADCALVA
                     IAPNTAP*"
     CDS             5877..7228
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834512"
                     /pseudo=False
                     /translation="VDFCALPVAGKLCDAADAIDFVSDPGKAITEGIGNWIAKSCGELA
                     AAAADLAAEAVNTTTKIDLGAGWFRDNYEMLLPIGLTILVATFCAQLVRAAMKRDGQAL
                     GQAFTGTVGGVIFCFAAIALTTVAIEVVDALSDSLFAAAGTSIDDAVRRMVKVSQIAAI
                     SPLGWLVAALAALGAAVGAVMYWCVMMVRKVGILVLVTLAVFAGAGGGWEAARRWRRGW
                     IEATATLIVSKLLMTVVFLLGISAMGKTDADGGIAALADVMAGIVIMLLVMLCPYATFK
                     FVHWAAESTDGETLHRSGGAGAQLAKQHAENATRKAASAAATVGTGGAAAGAGAASPQG
                     PAAGSGAFPGDIASSPSGSGGGTGASPAMDKVQSGLNEAVSSMPTSPAAQDSGNSVGVG
                     NSAPGGPPAGATPRSTQDGAPPSAGVVGAAQGSESGTGGSPFTTPQSPAGS*"
     CDS             7314..8785
                     /protein_domains="PF11203"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834513"
                     /pseudo=False
                     /translation="LSDLTITPMTVKFPTRSRRGILLGLSLPQLALTSAALALLLVTVV
                     TTGLPGALILTPLWAGVAALVAVRRRGRSLIDWAPIVARYAQRRRTGQTLWLARPVSRP
                     RAEGTLHLPGTAASIKVVTPADGQAAALHDPHQQTLTAVARVTSRAFALLDPATQNSHV
                     QAWGRALAGIARTGHVATVQVLERTVPDSGDTLTRHWNTHGRPGTQLAGQVYSDLVASA
                     GPAAAPHETYLAISLDLKAAKRLISQAGGGLPGAFTVLGQATSSLTQAARTAGLTVNGW
                     LNAREIAAVIRTAYDPKALAALQQWSDTGRAEADPAAAGPVVQVEEHDRLITDTARHTT
                     YWVENWPRTEVLAGFLHQLLFTAGVRRSFSLIYVPQGFESAIRDVQRTKATIIADANER
                     ARRGQVDSEADVVEYGDVKERERQLIAGHADVAMTGLLTVSADTDQALDAACAQIETAA
                     VTAQVDLRRLDYQQPDAFALAALPLARTAQEK*"
     CDS             8837..9246
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834514"
                     /pseudo=False
                     /translation="LATTTTDPTDAHPYLRAATAGIRHHARSIGRGTPADRRHLDNLHE
                     HVTRLHLLLDQLAETVRPEHPTSGRHLATAHLRLWQATASLHDAFHTLPAAPACTPDRL
                     PDGPVVLTICQRHLASGHAVRRKTTPADHGTA*"
     CDS             9278..10791
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834515"
                     /pseudo=False
                     /translation="MSRHRPGRRARRASASPLFTPHGADRTTRRAARKQLAEARAKAQA
                     AAVETTGTTAAEAEMPAPLYAPAGRPGTASARGKRLRLPAHRMTTATASGAYPFLAEGG
                     LGAEGIYIGRDVHAEGSFVFDPFSLYGKVEGFTNPNILLAGVIGQGKSALAKSFALRSV
                     AFGYRVYVPCDPKGEWTPVATALGGTSIALGPGLPGRLNPLDAAPKPPSVSDADWAGEV
                     RKRRLLLLGSLARTVLGRDLLPMEHTALDIALDGVVQAATAAGRAPLLGDIAHTLAQPH
                     LLDAAAGTVSGHLGDAARDLSHALRRLVHGDLAGMFDAPSTVAFDPTSPMLSIDLSRLG
                     GSGDDTALVLAMTCASAWMEAALTDPDGGRRWIVYDEAWRLMRHPGLLQRMQAQWKLSR
                     GLGIANLMVIHRLSDLLTAGDAGSQGRALAEGLLADCSTRIIYRQETDQIQAAATLLGL
                     TAVETEAISHLTRGRGLWRVAGRSFVVQHLLHPTEKSLFDTDARMH*"
     CDS             10873..11060
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MKRSWQPWPSTSGKTASSIPSSSTPTVGSSTDAPDSSPVNVQASN
                     RVSTRTKAESPPSTHCP"
     CDS             11100..11671
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834516"
                     /pseudo=False
                     /translation="MITVKARSESEQEARSESEHGSRSESEQTARALGDQVGIAVAFLG
                     RASTVLQHAPDLVDAVISGTMGLDEAYGVARENKERANGAEAQLARLRAEDPRLADRVV
                     EGALTIQGAWAERKARLEEDLRQRRVATNLLCEILPALAQIRGSRTFTQYDPELAPPGR
                     AVTREVIEHAATALAEIAAVWKDRDLP*"
     CDS             11669..12180
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834517"
                     /pseudo=False
                     /translation="VKYSSDPQLRQLALEAAQHVTTDIGRMHKDDFLDDLCARIRERDD
                     LEGAVLRKAAQGLMRDLGERRSPRRNKRTGGLYHPESIIKLGNGIWVWMKHTTPTDMTQ
                     WGLISSRNTVRTITAAADTQQYIHERTDAFRSHPGISSLHPLEEAVFQYQQDTLDDADW
                     DRDHEDL*"
     CDS             12233..13050
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834518"
                     /pseudo=False
                     /translation="VLRNSPPLETFALEIADRLPGHWTSAYHLHPSYRDQFPTADRLWD
                     NGHVDWAVGEFVLGHDSVLTGPAGQELYIVDRPLRPKQFLVAALEPPGFLPHHFHGVPE
                     PNGIVISADPVRAAAAITRRLLPRYARAAEAVREQARRRPAPPAHRQAPAETSAVTLVR
                     YEDGLLGAPYGHVPAEARDTLYLTGFQYVPNQGAFLLRSESGPVATAVRIQVLADRLAK
                     LGIGLNYRHPAAVSGTTVVTTGRANAPQASRVATGAALHSAAPRSWGRAR*"
     CDS             13259..13836
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834519"
                     /pseudo=False
                     /translation="LGSPAFIARPDPDGGYTGVHLQYDSSPPNMVPLLLAAYRFRFGRD
                     LEALSRYLVDDVAFAWEEIGTDLLDGSPPGLLQRLTGGEQWPSREMTGVVNLDGTPAER
                     DVITQHSSEGHHWGYVLHPAGIEVISRQMDARGPVISWDTDPRTHFSEAMALWMPGTPP
                     PMSLPRDLPRLTPTPPAAPARTATRPPRR*"
     CDS             complement(13779..13924)
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_4834520"
                     /pseudo=False
                     /translation="MGGGGSDEPVVGVPAEGEVLIQEDSLKRAVSGVGVEWRSVQELLA
                     AWE*"
     CDS             13995..14290
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834521"
                     /pseudo=False
                     /translation="MYRLAMPEYDGVRRARQAVHDLRQRGFDVYADYTLDPSQSAGPPR
                     VQPRAGLMERRSRIAQAAGIRSAQYRPTVSAQAAPAPSRPVGSIPVSGHGRGR*"
     CDS             14288..15015
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834522"
                     /pseudo=False
                     /translation="VTDDLITIVRGRGGEVEAEGPMDSLASELLARAGFVKEYTLRGIG
                     HRLPFDMGVEWENEHASRAAEMLRAARYPVRIDPALAPASVPSADGVDVPPSVAAAAQT
                     LKARAAGGTDLQQPHEAGRALAALAQGEDSLLRPAADVLLAVATAVSSLPSPAHDRDAR
                     RLAELSGVLRVVETEVDRIALRLRAAPDVTSNAGRTKQAAVEVPAKLQSLIHRLGHARA
                     REYEAHLPVPAAPGEPGRSR*"
     CDS             15013..15431
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834523"
                     /pseudo=False
                     /translation="VTVADQTPAGTELRRRARAQTLRYLAALALPDPAESVRAWAQHLG
                     DEQCAAEVHVIVDALTGTATSPLLALRDALRTTGGWCREHGQPVLAERYVRAADLLDIA
                     DRQLYQLGIDHLTAFHTEPCPPGHQHREDTAPELP*"
     CDS             15536..16485
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4834524"
                     /pseudo=False
                     /translation="MELSGFDKNDSGDMVLPLSDLAHARQALITLGAVAERILGLQLTP
                     SSEQYIGDIALDVAEHLPGQWTARVENYSLRVWQEDLAGGLWSTGPIAQTLAADRVRQA
                     ALLKRDDGMELAVVKDPHLDTYHVGALRPDHVPGPTNATAPPGVTVQPTASAAAHVIRT
                     RLLPAYTRSVLQAHASDLSDDLTWARETYEAGTIPDPAPADLVDAYIRFTASAPLVIAA
                     IRTLGAPTDYEVDFLHRVEVIVTAPADETGPKPVTAHPDPLGWWLVEGGDELVALSLRT
                     LASVPPPLEQGRRTGSRTLALAPAPALSEPTVRRR*"
ORIGIN
        1 tcagcgcgtg cgggtggcgg cgtcgggcca ggcaccgggg cgtggcgcgg ggcggctcgt
       61 gacacggctg gaggggcgag cggccagcgc ggcgcggcct gcgtcggtga gggcgaccgg
      121 ctgtccggcg tgcagcgggt ggctggtgtc gcggtcgacg agcccggccg tctccagccg
      181 ggcgaagtca tgctggccga tcctggtgcc ggaggcggtc acgacggaga gccgctgggt
      241 gagcaggtgc tcgcggagct tggcgccctg gccgatcgcc aggagcaggg cgatgtcgtg
      301 ggctttcagg tcggcgtggc cggcaggggt gcgggcggcg tttgcttcga cgggctcgag
      361 gacgtcggac agctccgtct cgcgaacgcc gcggatgcgc acagcctcct ggagctgctt
      421 gaccgtgcgg ccgatgcggt cgaagagcgc ggagtccatg gggtactcgc cgctggcgag
      481 gcgttggagg agcacgcggt agaaggtgac ggactgctcg gcgctggaca gggatcggtg
      541 ggcggcggcg acgctctcgg tctgctcgtc gagcaggccg cggtcgtggt cgcgccagag
      601 ccggtcgacg gtgtagccga cggcaagctc gacgcggtgg tcgagggacg tcagcgcctt
      661 gcggacgggc gtcgtcgtgg accgggtcac gttcgcgcgg ccccggtcac tgccgtcggc
      721 agccacgccg ccccgcagcg tcctcgtcgc cggcgtggtc gacggcttcg tagcagtctg
      781 gggagcagtt gtcggggtcc ttctcgcagg aggactcctc cgcgggagcg cagcagcagg
      841 gggcggacag caggacggcg agttcctggc cggcggcgat gcggtcgatg aggatctcgg
      901 tgcaggcgtg gaagccgtcc ggcgtgatgt ccgggtgtgg tttggtcagg gtctccagca
      961 ggcggcgctc cagctgctgg acctcgatgt aggtctccag cagcgcgcgg tggtgggggt
     1021 tctccggctc ggccgggagc tccaggaggt tctcgccgaa gtggtcaagg aagttcggga
     1081 aggctgtcaa cgtacggctt tcgtggtgag gacggtgggc tgggcggagc ggggaaggcc
     1141 ggggggtggg ccgggcttcg ggatctcgcg gtaggcgtcg atctggggtg agcgggtgcg
     1201 tgcggcgtgc gcgcgggcgc cgaccggacg gtggtcgatg ccgaggcgtc gggccacggt
     1261 gtcgtagatg tcgtggttgg cccgggggcg gacggccacg acgtggatct ccatgggata
     1321 ggccgaggtc tgcggggccg gccgtagcgc gtagacgatc cgccaggcgg cctggcggtc
     1381 gacgtagagc ttgcgcagtc cggcgagttc ggccgtgagc ttgcccccgt gccggtctgc
     1441 gttgacgacc tcctggagca gcgcgagcga caggtcgcgg atgtcgctgg gggcctggag
     1501 caggtcggtg agggcgcgcg ggtcgaaggt gaggccgaag gcgggcggcc ggccctcggc
     1561 gctcactcct ccgcctgcgc cgtctcagcg tcgcgggcta cggcgcgcac ggagcggcca
     1621 gggccgcgaa ggaggcggtg cgacggccgc tcggggtcgg tctggcaggc ggacagcggt
     1681 ccgccggcgg cccggatggc ggccatgcag tgggtgagga agtcccggtg ccagacgaag
     1741 ggaccggccg gtccggcctc ggggtccttg tgctgcaggt aggccatcca cagggcgtgg
     1801 agccaggcga cgacgtcgag gtgttcctgc cactggtcgc accacgggga ggcggtggtg
     1861 acctcgctcc cgtacgtggg catgaggaag tcctccaccc agtcggtgag caggtccagc
     1921 tcgctctcgt actcctcgcc gtccagctcc agaatcggac gcggctccgg cggcatcatc
     1981 gccgcggacg gcatcggcgg caggccgaag ccgggcagcg acaccggtcc cggtgcggcg
     2041 gcgaggtggt cgagctgccg cgcctgctcg gcggagcggt cgagcagctt gcggacggtg
     2101 gcctggatgc tgtccaggtc gccttccgga aggcgcaccg ggtcgaattc cccggcggcg
     2161 ccgaattcct ccagagggtc aggctccaag gaaatctcct cctccggcgc acgcggcagc
     2221 cggaaattca agaacgggtg atggggcggc agggctcgaa tgcgcgcagg cgcggataac
     2281 gaaccgcccg taactcgcgg ttgcgcgcat ccgggtcagg acgtcagggt gaggtcgtcc
     2341 tgtccgaggg tctggtggag cgtttcggtg aggcggtcgg aggcgatctc ggcgtagtgc
     2401 cgggtcttct cgacgccgat gaagtcgcga ccctccagga gagcggccac accggtggaa
     2461 ccggagccgc aggtgaaatc gaggacggtg ccgccgggcg gggagatctt caccagctcg
     2521 cgcatcacct cgaccggctt ctgcgtgatg tgctgccggg ccttgcccga cggctgcgac
     2581 gccgagtaga ggccgggcag gtagacgggg ttgcgggagc cgtcgatcgc accgttcgac
     2641 gcccacacga tgaactcaca ggactgcttg aaacggccct tctgcgggcg ggcctgcggc
     2701 ttgtgccagg ccaggacgcc gcgccacagc catccggccg cctggatcgc gtcggtggtg
     2761 accggcagct gccgccagtc ggtgaacagg agcgccgcac cgccgggctt cgtcagccgg
     2821 tgggcctcgg tcatgatctg cgtcagccag aagccgtagc tcctttggtc catgttctcg
     2881 ccggggaagt ccgccagctc atggccggca tcggcggagg tgtacttctg tcgagcggtc
     2941 cgggaggtgc gctccttcgc ggtccgcccg ccggagttgt acggcgggtc ggtgatgacc
     3001 gcgtccacgc agtcgtccgg aaggccggcc aggacgccga gcgcgtcgcc gtggtgaagg
     3061 gaaaaaggca aaggggtacc ccgattcggg tcacgaaaga gagtgggaat cccgcctcgc
     3121 actgaatgcg ggcgccgcgg cggcgaatac aggcgcggaa ggccggcatg ccgaaggaga
     3181 gcggcgggca agcgggggaa gccacactgt aggacacgat tcccggttga cccctgcgag
     3241 gcgagaaatt aggtcaaccg ggaatcggca cctacagtct gaccaccgcc cggccccagc
     3301 agccgaacgg ccacccctcc ccctgccttt ctggaggcac agccttgtcc tgaccccgct
     3361 cccgatgccc ccgaggacgc ccgaccggcg agaggcaact cgccccgcgg ccactcctcc
     3421 caggctttcc gatcacctca atctcggccc tcgcgccctt ctcacctcgg accagcgcgg
     3481 ccggacttca cctcaaggac cactcgtgac acagccgtac tctcccctgc ctccaaccct
     3541 gcgtagaacc ctcgccccct cgggaggctc agcggattga agggcatagc cgcagccgtc
     3601 ggcgtcgtcg tcctctctcc gctcctcctg gccggcgcag ccgctacagc ggctgccgcc
     3661 agcagctccg cttcccgcgc cacgcagtgc ggcgtcgaca acacggtcga cgccaacgcc
     3721 gtcgcccagc aggtcgcagg catcctcggc ggctccggcg ccacccccgg catccagatc
     3781 aagggcctgg agctgcccgc cgagcagatc cctcacgcca agacgatcat cgccaccggg
     3841 atcgccatga aggtccccga gcgcggccaa gtcgtcgccc tcgcgaccgc gatacaggaa
     3901 tcccgcctgc gcaacctccg ctacggcgac cgcgacagcc tgggcctgtt ccagcagcgg
     3961 ccgagcatgg gctggggcac cgccgaggag atcctcgacc ccgtccacgc ctccacccgc
     4021 ttctacgagg gactcctcaa ggtcgcgggc tggcagcaga tgacgatcac ccaggccgcc
     4081 caggccgtcc agatctccgg ctatcccgac gcgtacgccc agtgggagtc gctcgcccgt
     4141 gctctgcagg aggcgatcgt caagaccctc cctcagggcg gaggcgacac cggggctccg
     4201 ggcggcccgg ctggcggcgg ctgccgaccc ggcgaggacg ggtcgcagtg gggcgagatc
     4261 ccccagggca ccgttcccgc cggttacaag attccagccg acgcctcccc gaaggcccgc
     4321 acggcgatcg agtgggcgat gcaccagctc ggcaccccgt accagtgggg cggtacctgc
     4381 aaggactccc acgggccgga tccgatgggc cgctgcgact gcagctccct gatgcaggtc
     4441 gcctacgcga aggccggcgt caccctcacc cgcaccacgt acacccaggt caaggagggc
     4501 gtcccggtcc cggtcaccgc gctcaagccc ggcgacctgc tcttcacccg cggcaccgcc
     4561 gccgttcccg agcacgtcgg gatgtacatg ggagcgggtc tcgtgatcaa cgcgccgaag
     4621 accgggcgcc ccgtgcggat cgagaaggtc gccgactggc agatcctcgc cgtccgccgc
     4681 atccccgccc tcagctccta gcgctccccg cccgcttccc gggccacggg ccgcttcccc
     4741 ctgccgccgc gagccgcatg ccgccgcgcg ccttcccctc ttcctctttc ccgctgggcc
     4801 atctgtcctg cgctcgcaag gagttcgacc atccccaccc tcgctcacct ccagcagata
     4861 gccgaccgcg tcacgtacct ggcctacgac cccggcgtct ccccgaaggg cggcttcctg
     4921 ccgggcctgg acctgctgcg caacgtcgtc agctccatca acatggccgc gatcatcgcc
     4981 gtcgtcggcg ccctcgccgt ctccctcggc gtgtgggcct ggggccacca caccggtggc
     5041 caccaggccg aggccaacgg gaagaagggc gccctcgtgt ccgcgggcgc cgcgctcggt
     5101 ctcggtgccg ccaacgggat catcgcgttc ttctccacgc tcggcacgca ggtccgctga
     5161 tgggcaagcg ctcccgccca cgcgtccgcg ccgccaccgc ccactggtcc accggccggc
     5221 gcgtcgccgt cctcgccgcg gtcctggccc tgctcctggc cggcgccggc cttgccgcct
     5281 acctcacgac cggcggcggc cggggcaagg caccctccgg caagccgtcc gtcagcaatc
     5341 cgaccgcccg tccgggcacg tccgcacccg tcgcggaggc tgcgacgggg acggtctccc
     5401 cgccgccgcg gctgtccgat cctctcgcct acggccgcgc cgcggcggtg atgctctggt
     5461 cctacgacac ccgggccacc acccgcgacc agcagctcgc cggcatgcac gcctggatga
     5521 cgaccgagac gaagtacacc gactggacct cgatccaggc ccaggtaccc gacccgctgc
     5581 tgtggtcgcg gatgcacgac cagggtcagc acgccaccgc gaccgtctcc cagtcgcact
     5641 tcccctcggc gttcaagcag gccctggccg agaacccggc cgccctgacc gaggcgtaca
     5701 tctacgccgt caccgtcacc ggcaagcagg ccatcgcctg gaaggacggc ggaggcggcg
     5761 ccgaggaccg ctcggtcacc ctcgccgtgc agtgccgacc cagcgccgac tgcgccctgg
     5821 tcgccatcgc gccgaacacc gccccctgac ccgcaacaga taggaggagt ccgtcgtgga
     5881 cttctgcgct cttccggtcg cgggcaagct ctgcgacgcg gccgacgcga tcgacttcgt
     5941 ctccgacccg ggcaaggcga tcaccgaagg catcggcaac tggatcgcca aatcctgcgg
     6001 cgaactcgcc gcagcagcag ccgacctggc cgccgaggcc gtcaacacca ccaccaagat
     6061 cgacctcggc gccggatggt tccgcgacaa ctacgagatg ctgctgccga tcgggctcac
     6121 catcctggtc gccaccttct gcgcccagct cgtccgggcc gcgatgaagc gcgacggaca
     6181 ggcactcggc caggcgttca ccggcaccgt cggcggcgtg atcttctgct tcgccgccat
     6241 cgccctgacc accgtcgcga tcgaagtcgt cgacgccttg tccgactcgc tgttcgcggc
     6301 agccggcacc tcgatcgacg atgctgtccg ccgcatggtg aaggtctcgc agatcgcggc
     6361 gatctccccg ctcggctggc tggtggccgc cctcgcagcc ctcggcgccg ccgtcggcgc
     6421 tgtcatgtac tggtgcgtca tgatggtccg caaggtcggc atcctcgtgc tcgtgaccct
     6481 ggcggtcttc gccggagcgg gcggcggatg ggaagccgcg cgccgctggc ggcgcggctg
     6541 gatcgaggcg accgccaccc tgatcgtctc caagctgttg atgaccgtgg tcttcctcct
     6601 cggcatctcc gccatgggca agaccgacgc ggacggcggg atcgccgcgc tcgccgacgt
     6661 catggccggc atcgtcatca tgctcttggt aatgctctgc ccctacgcga ccttcaagtt
     6721 cgtgcactgg gcggcggagt ccaccgacgg tgagaccctg caccgctccg gcggggctgg
     6781 tgcccagctc gccaagcagc acgccgagaa cgcgacccgt aaggctgcgt ctgcggcagc
     6841 gaccgtgggt accggcggcg ccgccgccgg ggccggagct gcatcgccgc agggcccggc
     6901 cgcaggatcc ggcgccttcc ccggtgacat cgcctccagc ccctccggaa gcggtggcgg
     6961 cactggagca tcaccggcca tggacaaggt ccagagcggc ctgaacgagg cggtcagctc
     7021 catgccgacc agcccggcgg cccaggactc gggcaactcc gtcggggtcg gcaacagcgc
     7081 ccccggcgga cctcccgcgg gtgccacacc gcgcagcacc caggacggag cgcctccgag
     7141 cgccggcgtc gtcggtgccg cgcagggctc cgagtccggc acgggcggca gcccgttcac
     7201 gacgccgcag tcccccgccg gttcctgaca cccgacactc ccctggttcc cgggacggga
     7261 cacgaacgct gtgtcccgtc ccgggggccg cctccttcgg aaagcccttg ccttgtctga
     7321 cctcacgatc accccaatga cggtgaagtt cccgaccagg tcccgccgcg ggatcctgct
     7381 cggcctctcg ctgccccagc tcgccctcac ctccgcagcg ctcgcgctgc tcctggtcac
     7441 cgtcgtgacc accggcctgc ccggcgccct gatcctcacc ccgctgtggg cgggggtcgc
     7501 cgccctcgtc gccgtccgcc gccggggccg gtccctgatc gactgggcgc cgatcgtcgc
     7561 ccgctacgcg cagcgccgcc gcaccgggca gaccctgtgg ctcgcccgtc cggtgtcccg
     7621 cccgcgcgcc gaaggaaccc ttcacctgcc gggaacagcc gcttcgatca aggtggtcac
     7681 cccggccgac ggccaggcag cggctctgca cgatccccac cagcagaccc tcaccgcggt
     7741 cgcccgggtg accagccgcg ccttcgccct gctggacccc gccacccaga actctcacgt
     7801 ccaggcgtgg gggcgggccc tggccgggat cgcgcgcacc gggcacgtcg ccaccgtcca
     7861 ggtcctggag cggaccgtcc ccgactccgg cgacaccctg acccggcact ggaacaccca
     7921 cggccggccc ggtacacagc tcgccggtca ggtctacagc gatctcgtcg cctccgccgg
     7981 cccggccgcc gccccgcacg agacgtacct cgccatctcc ctcgatctga aggccgccaa
     8041 gcgcctgatc agccaggccg gcggcggact gcccggagcc ttcaccgtcc tcggccaggc
     8101 cacctcctcc ctcacccagg cagcccgcac cgccggactg accgtgaacg gctggctgaa
     8161 cgcgcgtgag atcgccgccg tcatccgcac cgcctacgac cccaaggccc tggccgcgct
     8221 gcagcagtgg tcggacaccg gccgcgccga agccgacccc gccgccgccg gccccgtcgt
     8281 ccaggttgag gaacacgacc ggctcatcac cgacaccgcc cgccacacca cctactgggt
     8341 cgagaactgg ccgcgcaccg aagtcctcgc gggcttcctc caccagctgc tgttcaccgc
     8401 cggggtgcgc cgctccttct ccctcatcta cgtcccccag ggcttcgagt ccgcgatccg
     8461 cgacgtccag cgcaccaagg cgacgatcat cgccgacgcc aacgagcgcg cccgtcgcgg
     8521 acaggtcgac tccgaagccg acgtcgtcga gtacggcgac gtcaaggaac gcgagaggca
     8581 gctcatcgcc ggccacgccg acgtcgccat gaccggcctg ctcaccgtct ccgccgacac
     8641 cgaccaggcc ctggacgcag cctgcgccca gatcgagacc gccgccgtca ccgcccaggt
     8701 cgacctgcgc cgcctcgact accagcagcc cgacgcgttc gcccttgccg cactccccct
     8761 cgcccgcacc gcccaggaga agtagggccc cgccgcctga tccatccagg ccaccgcaga
     8821 aagaccccca ccctcttggc caccaccacg accgacccga cggacgccca cccgtacctg
     8881 cgggccgcga ccgccggcat ccgccaccac gcccggtcca tcggccgggg caccccggcc
     8941 gaccggcgcc acctcgacaa cctgcacgag cacgtcaccc gcctgcacct gctcctcgac
     9001 cagcttgccg agaccgtgcg ccccgaacac cccacgtcag gacggcatct ggccaccgcg
     9061 cacctgcggc tctggcaggc caccgccagc ctccacgacg ccttccacac cctgcccgcc
     9121 gcccccgcct gcacccccga ccggctcccc gacggcccgg tcgtcctcac catctgccag
     9181 cgccacctcg cctccggcca cgccgtccgc cgcaagacca ccccggccga ccacggcacc
     9241 gcctgagcca cctcgcgcag aaacgatccc ccagccatgt cccgacaccg ccccggacga
     9301 cgggctcgcc gcgcctcggc cagccccctg ttcaccccgc acggcgccga ccgcaccacc
     9361 cggcgcgcag cccgcaagca gctcgccgaa gcccgcgcca aagcgcaggc cgccgccgtg
     9421 gagaccacag gcaccacggc ggcggaggca gagatgcccg cgccgctcta cgctcccgcc
     9481 ggccgccccg gcaccgcctc cgcccgcggc aaacgcctgc gcctgcccgc ccaccgcatg
     9541 accacagcca ccgcgagcgg cgcctacccc ttcctcgccg aaggtggcct cggcgccgag
     9601 ggcatctaca tcggccgcga cgtccacgcc gaagggtcct tcgtcttcga ccccttctcc
     9661 ctttacggga aagtcgaggg cttcaccaac ccgaacatcc ttctggccgg ggtcatcggc
     9721 cagggcaaga gcgccctcgc gaagtccttc gcgctccgct cggtcgcctt cggctaccgc
     9781 gtctacgtcc cgtgcgatcc gaagggcgaa tggacgccgg tcgcgaccgc gctcggcggc
     9841 acttccatcg ccctcggccc cgggctcccg ggacggctga acccgcttga cgccgccccg
     9901 aagcctccgt ccgtctcgga cgcggactgg gccggcgagg tccgcaaacg ccgcttgctc
     9961 ctgctcggtt ccctcgcccg caccgtcctc ggccgtgacc tgctccccat ggagcacacc
    10021 gccctcgaca tcgccctgga cggagtcgtc caggccgcca ccgccgccgg ccgagccccg
    10081 ctcctcggcg acatcgccca caccctcgcc cagccccacc tcctcgacgc cgccgccggc
    10141 accgtctccg gccacctcgg cgacgccgcc cgcgacctct cccacgccct gcgccgcctc
    10201 gtccacggcg acctcgccgg catgttcgac gccccctcca cggtggcctt cgacccgaca
    10261 agcccgatgc tctccatcga cctgtcccgg ctcgggggat ccggcgacga caccgcgctg
    10321 gtactggcca tgacctgcgc ctccgcgtgg atggaggcag ccctcaccga ccccgacggc
    10381 ggccggcggt ggatcgtcta cgacgaggcg tggaggctga tgcgccatcc cggcctcctc
    10441 cagcgcatgc aggcccagtg gaagctgagc cgcggcctcg gcatcgccaa cctcatggtc
    10501 atccaccggc tgtccgacct gctcaccgcg ggcgacgccg gatcccaggg ccgagccctc
    10561 gccgaaggac tcctggccga ctgctccacc cgcatcatct accgccagga aaccgaccag
    10621 atccaggccg ccgccaccct cctcggcctc accgccgtcg agaccgaggc catctcccac
    10681 ctcacccgcg gacgcggcct gtggcgcgtc gccggccgga gcttcgtcgt ccagcacctc
    10741 ctccacccca cagagaagtc gctcttcgac accgacgccc gcatgcactg agtgccaacc
    10801 gaccaacact gcacatcgac aggacaacac catcgacatc cacccgacca cctcgcttct
    10861 cccgcacctg ggtgaagagg agctggcagc cctggccctc gacatccggg aaaacggcct
    10921 cctccatccc atcgtcctcg actcccacgg tcggatcctc gacggacgcg cccgactcgt
    10981 cgcctgtgaa cgtgcaggca tcgaaccgcg tttcgacacg tacgaaggcg gaatccccgc
    11041 cgtctacgca ctgtccgtga acttgcaccg ccgccatctc tccaaggggc aggttgcaat
    11101 gatcacggtg aaggcccgtt ccgaatcgga acaagaggct cgttccgaat cggaacacgg
    11161 cagccgttcc gaatcggaac agaccgcacg agcccttggg gatcaggtcg gaatcgccgt
    11221 cgccttcctc ggacgcgcca gcaccgtcct gcagcacgca cccgaccttg tcgacgcggt
    11281 gatcagcggc accatgggcc tcgacgaggc gtacggcgtc gcccgggaga acaaggagcg
    11341 cgccaacggc gccgaggccc agcttgcccg acttcgcgcc gaggaccctc ggctcgcgga
    11401 ccgcgtcgtg gaaggcgcgc tcaccatcca gggcgcgtgg gcagagcgga aagcccgact
    11461 cgaggaggac ctgcggcagc gccgggttgc caccaacctg ctctgcgaga ttctccccgc
    11521 cctcgcccag atacgcggca gccgcacctt cacccagtac gaccccgaac tcgccccgcc
    11581 cggccgcgcc gtcacccgcg aagtgatcga gcacgccgca accgccctgg ccgaaatcgc
    11641 cgccgtctgg aaggaccgcg acctcccgtg aagtactcct ccgaccccca gctgcgccag
    11701 ctcgccctcg aagccgccca gcacgtcacc accgacatcg gccgtatgca caaggacgac
    11761 ttcctcgacg acctgtgtgc ccggatccgc gagcgcgacg acctggaggg cgccgtcctg
    11821 aggaaggccg cccagggcct gatgcgggac ctcggcgagc gtcgcagccc tcgccgcaac
    11881 aagaggaccg gcggcctgta ccaccccgag agcatcatca agctcggcaa cgggatctgg
    11941 gtgtggatga agcacaccac cccgacggac atgacgcagt ggggcctgat ctcctcgcgg
    12001 aacaccgtcc gcaccatcac cgccgccgcg gacacccagc agtacatcca cgagcgcacc
    12061 gacgccttcc gctcccaccc cggaatctcc agcctccacc cgctggagga agccgtcttc
    12121 cagtaccagc aggacaccct cgacgacgcc gactgggacc gcgaccacga ggacctgtag
    12181 gcgccccagc ctcgtacctc gactggccac gcccacgaca tatcggagac cgtgctgcgg
    12241 aattcacccc cactcgaaac cttcgccctg gagatcgcag atcggctccc gggtcactgg
    12301 acaagcgcgt atcaccttca cccctcctac cgcgatcagt tcccgaccgc tgaccggctg
    12361 tgggacaacg gtcacgttga ttgggctgtc ggcgagttcg tcctcggcca cgactcggtc
    12421 ctcaccggac cggccggaca agagctctac atcgtcgacc ggcccctcag acccaagcag
    12481 tttctcgtcg ccgcgctgga gccgcccggc ttcctgccgc accatttcca tggcgtgccc
    12541 gagccgaacg ggatcgtgat cagcgctgat cccgtccgtg ccgccgccgc gatcacccgc
    12601 cggctcctcc cccgatacgc ccgggccgcg gaggccgtgc gcgagcaagc gcgacgacgg
    12661 cctgcccctc cggcccaccg acaggcaccg gcagagacca gcgcggtcac gctcgtccgc
    12721 tacgaggacg ggctcctcgg cgccccgtac ggacacgtcc ccgctgaagc ccgagacacc
    12781 ctgtacctga ccggattcca gtacgtcccg aatcagggtg cgttcctcct gcgttctgag
    12841 tccgggcccg tcgccacggc cgtacgcatc caggtcctcg ccgaccggct ggccaagctc
    12901 gggatcgggc tcaactaccg ccaccccgca gcggtatcgg gcaccaccgt ggtcacgacg
    12961 ggccgcgcca acgcgcccca ggcgagccgg gtcgctaccg gggcggctct gcactccgcc
    13021 gccccgcgct cgtggggccg cgcgcggtaa cccaagccat gccgctgcag acagaaggct
    13081 ccctgccttc ctgaaccgac tctgccgacc acggtccggc gacggccggc gtgcacggct
    13141 cgagcctcga ccgcgccgat ctgcccgatt ctcgcccagc agccacgccc cggccgcccg
    13201 tgtcctctgc gccccagccc aggcacgccc cgtaatccct tctcccctgg agccttcttg
    13261 ggatcccctg ccttcatcgc ccgccccgac ccggacggcg gctacaccgg cgttcacctc
    13321 cagtacgaca gcagcccgcc gaacatggtg ccgctgctcc tcgccgccta ccgcttccgc
    13381 ttcggccggg acctcgaagc cctcagccga tacctagtgg acgacgtcgc cttcgcctgg
    13441 gaggagatcg gaaccgacct cctcgacgga tcacccccgg gcctgctcca gcggctgacc
    13501 ggcggcgagc agtggcccag ccgcgagatg accggcgtcg tgaacctcga cgggacgccc
    13561 gccgagcggg acgtcatcac ccagcacagc tccgaaggtc atcactgggg gtacgtcctt
    13621 catccagccg gcatcgaggt catcagccgc cagatggacg ctcgcggccc ggtcatctcc
    13681 tgggacaccg acccccggac ccacttcagc gaggcgatgg cgctgtggat gcccggcact
    13741 ccgccgccga tgtccctgcc ccgtgatctg cccaggctca ctcccacgcc gccagcagct
    13801 cctgcacgga ccgccactcg acccccacgc cgctgaccgc tctcttcaag gagtcctcct
    13861 gaatcagcac ttcaccttcg gccggcaccc cgaccacggg ttcgtcgctt ccgccaccgc
    13921 ccatacaccg cctcatctgg cgcactggta cctgaccgcc gagcagttcg agcccgtccc
    13981 cgagcagccg gggatgtacc ggctggccat gccggagtac gacggagtgc gccgtgcgcg
    14041 gcaagccgtc cacgacctgc gccagcgggg cttcgacgtc tacgccgact acaccctcga
    14101 cccgtcccag agcgctggcc cgccccgggt ccagccccgg gccgggctga tggagcgccg
    14161 ctcccggatc gcgcaggccg ccggaatccg ctcggcgcag taccggccga ccgtctccgc
    14221 ccaggccgcg ccggcaccct cacggccggt gggctccatc ccggtctcgg gccacgggcg
    14281 tggccggtga ccgatgacct gatcacgatc gtccgcggtc ggggcggcga ggtggaggcg
    14341 gagggaccga tggacagcct ggcctctgag ctgctcgcgc gtgcggggtt cgtcaaggaa
    14401 tacacgctgc gcggcatcgg gcaccgtctc cccttcgaca tgggcgtgga gtgggagaac
    14461 gagcacgcct cccgggccgc ggagatgctg cgcgccgccc gctaccccgt ccgcatcgac
    14521 ccggctctgg cgcccgcgtc cgtcccgtcg gctgacggtg tggacgtccc gccgtccgtg
    14581 gcagcggcgg cccagaccct gaaggctcgg gcggcgggcg ggacggacct ccagcagccg
    14641 cacgaagcgg gacgcgcgct ggccgctctg gcccagggcg aggacagtct cctgcggccc
    14701 gccgccgacg tgctccttgc cgtcgccacc gccgtctcga gcctccccag cccggctcac
    14761 gaccgcgacg cccggcgcct ggccgagctc agcggggtcc tacgggtcgt ggaaaccgag
    14821 gtcgaccgca tcgcccttcg cctgcgcgcc gcacccgacg tcacctcgaa cgcaggccgt
    14881 acgaagcagg ccgccgtcga agtcccggcg aagttgcaga gcctcatcca ccggctcggc
    14941 cacgcccgag cacgcgagta cgaggcccat ctccccgtac cggcagcacc tggtgagccg
    15001 ggacgaagcc ggtgaccgtc gccgatcaga ctccggccgg cacggagcta cgccgccgcg
    15061 cccgcgcaca gacgctccgc tacctggccg ccctcgcgct gccggatccc gccgagtccg
    15121 tccgggcctg ggcacagcac ctgggcgacg agcagtgcgc cgccgaggtc cacgtcatcg
    15181 tcgacgcctt gaccggcacc gcgaccagcc cgctcctcgc cctccgtgac gcgctgcgca
    15241 ccacaggggg ctggtgccgc gagcacggtc agcccgtcct cgccgagcgg tacgtgcgcg
    15301 ccgccgacct cctcgacatc gccgaccgtc agctctacca gctcggcatc gaccacctca
    15361 ccgccttcca caccgaaccc tgcccgcccg ggcaccaaca ccgagaggac actgcacctg
    15421 aactcccgtg aaccagccgc gggctccgtc acccggatca ctctgttcac cagcgaccgc
    15481 gatggcatcg tcggcctcgt cgacggtgac gcctggcagt gggcccgcac cgccatggag
    15541 ctgtccgggt tcgataagaa cgactccggc gacatggtct tgccgctgtc cgatctcgcc
    15601 catgcccgcc aggccctgat caccctcggc gccgtcgccg agcggattct cggtctgcag
    15661 ctcacgccca gcagcgagca gtacatcggg gacatcgcgc tcgacgtggc cgagcacctg
    15721 cccggacagt ggaccgcgag ggtcgaaaac tactcgctcc gtgtctggca ggaggacctc
    15781 gccggcggcc tgtggagcac cgggcccatc gcccagactc tggcggccga ccgggtacgg
    15841 caggccgccc tcctgaagcg cgacgacgga atggaactcg ccgtcgtcaa ggacccccac
    15901 ctcgacacgt accacgtcgg cgccctccgg cccgaccacg tcccgggccc gacgaacgcc
    15961 accgccccac ccggcgtgac ggtgcagccg accgcctcgg ccgccgccca cgtcatccgc
    16021 accaggctcc tcccggccta cacccgctcg gtcctgcagg cgcacgcctc cgatctgtcg
    16081 gacgatctca cctgggcacg ggagacctac gaggccggca ccatccccga ccccgccccg
    16141 gccgacctcg tcgatgccta catccggttc accgcctccg cgccgctcgt catcgcggcg
    16201 atccggaccc tgggcgcccc caccgactac gaggtcgact tcctccaccg ggtggaggtc
    16261 atcgtcacgg cgccggccga tgagaccggg ccgaagccgg tcacggcgca ccccgacccg
    16321 ctcggctggt ggctcgtgga aggcggcgac gagctcgtcg ccctctccct gcgcaccctc
    16381 gccagcgtgc cgccgcccct cgaacagggg cgccggaccg ggagccgaac gctggctctg
    16441 gcacctgcgc ctgccctgtc ggagcccact gtgagacgcc ggtga
//
