LOCUS       reptomyces_RBGC_217756 16741 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_217756
VERSION     Streptomyces_RBGC_217756
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_003814935.1
  ORGANISM  GCF_003814935.1
            .
FEATURES             Location/Qualifiers
     CDS             2..882
                     /protein_domains="PF00528"
                     /protein_domains="PF12911"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327462"
                     /pseudo=False
                     /translation="MTAVLQTTPTAEPVANYRLSLRRFTRNKLAVAGLTVVVLFLLFCF
                     VGPLLYSTDQTHTDLTQVNLGPSGSHWLGTDAVGHDELGRLMYGGKVSMLVGLAAGILA
                     TVIGTLWGATAGYAGGWLDAVMMRIVDAGIAIPALFILLVVSAITTPDTLGLIVVLGLV
                     SWLVPSRLVRAETLTLKSRDYVLTLRATGGTHGRAIRRHILPNSVSTIVVAATFQVADA
                     ILLVAYVSYLGLGVQPPKTDWGGMLSAGLTAAYSGRWWLIVPPGLAIILVVCAFNAIGD
                     GLRDAFDVRGRG*"
     CDS             880..2621
                     /protein_domains="PF00005"
                     /protein_domains="PF00005"
                     /protein_domains="PF08352"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327463"
                     /pseudo=False
                     /translation="VTETEGTKVANILEVEDLGVTFSTDTGDVPAVREVSLHVRPGETL
                     ALVGESGSGKSTVALAAMGLLPSNARASGRVSVDGTQVVGAGEAELARLRGRTASMVFQ
                     EPATALDPLTRVGAQIAEVVRNHRAVSRAEAAREAVELLRRVGIPEPERRASAFPFQLS
                     GGQRQRVVIAMAIANSPGLLIADEPTTALDVTVQAEILDLLRALAADSGTGVLLVTHNM
                     GVVADFADRVAVMLSGEVVESGPVEQVLLQPQHEYTQRLLEAVPRLAVEVPVVEESAVE
                     ASAVADVPREVVGAPVVAEGEPPAPEGDAVVELRDVSVRFGRGPGAVQALQDVSLTVRP
                     GETVGLVGESGSGKSTAARVALGLVAPSGGTVSLFGRELGRTRGRARRALLSGVGVVLQ
                     DPVASLDARMSVGECVAEPLRMHRRGLSAAERRTLVAEMLERVRLPRELAGRGPRELSG
                     GQRQRVSLARALVLEPRLLVADEPTSALDVSVQRTVLEVIAELQGELGFACLFVSHDLA
                     VVQRFAQRVVVMRAGRVEEEGPTMTTLLRPETEYTRRLIAAVPVPDPVVQRRRREALRT
                     GVTA*"
     CDS             2619..3568
                     /protein_domains="PF00480"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327464"
                     /pseudo=False
                     /translation="VTRAPEVVAGVDIGGTTTQVVLCAADFGIGDRLEVPTPADRGGAA
                     MVGAALDAVRLLLERTPVRLLGVGVGAAGLVDVRAGRILVASDSFRDWAGFEVTAAVER
                     ALGVPAFLDNDVNAFLRGEAAAGAVAGEPYVLGMTLGTGVGGALWLDGALYEGPHGAAG
                     EIGHVPGFGELPCTCGGRGHLETLASGRSIAARYGERTGRDLTAHEVADAAARGEADAL
                     AVYAAAGAGVARALLVTAGLLDVTTCVIGGGVSRSWSLLEPAIRRTLTAEPPVSGRALR
                     VLPAALGGDAVAVGAAARAWAELGAVGAAEERARA*"
     CDS             3759..5170
                     /protein_domains="PF05270"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327465"
                     /pseudo=False
                     /translation="MNARPHPGPHPAAHPSRRLFLGMAATVPLAATGALTLGAGTAHAA
                     DSAYVMAYFTESPDMLAANYGLHLAVSTDGLQWTPLNQNAPVATPTAGSLGLRDPFILR
                     KQDGTFVVLATDLNGTDWTYVSQYLHVWDSADLRTFTGYRRMKVHDLDTHAWAPEAFWD
                     AGRGQYAVIYSAVNSSGHNVIMVNYTTDFVTAGSPQVFFDPGYDVIDGDMAVGVGGYNY
                     LYFKKNSTLVGARSTSLDPGSFTEFSTAVSHNGTEAPTLVKPLTSSSTWYLWGDTWSPN
                     GVFYAWQTSSLAAGTWTALDQKTYTQPLNSKHCGIQPITAAQYSNLVAKWGTPAWNRLK
                     SYNYPARYVRHSNYVGRIDEYAFDPYADSQWKLVPGLADSAGVSFQSVNYPTRYLRHYD
                     YALRLDVNDGTSTFAGDATFYRTAGLADASWASFRSYNNPTRYIRHSNYVLRIDPVSTS
                     TEQQDATFYVGY*"
     CDS             complement(5277..6232)
                     /protein_domains="PF04069"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327466"
                     /pseudo=False
                     /translation="VTSNAPRSRSFRIHPAAAVALAATTALLAGCSSSSDDKSDPLAGD
                     KSDGKTVVVGSNNFAESILIADIYGEALKAKGIKVTYKPNIGSRETTYGLLKNGSITVL
                     PEYNGALLAYLDPKATPKTVEATTAAIDAKLDTKLTLLDPASAQDKDSVTVNAATAKKY
                     NLTAESSIADLKDIAKDLSIGASPEFQTRQQGLVGLKSVYGLEFKSFKALDAGGPLTQA
                     ALKKNTVQAADLFTTDPTIVQEKHVVLQDPENLFGFENVQPLVYKSGLSSEGVAALNAV
                     SAKLDTKALLDLDSQVQLDNKDPLDVAKAWLKTVGLG*"
     CDS             6223..6347
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MEVTIPVPDSGDWCEASAATDPIQPVLTQSRAAWSPIGLNA"
     CDS             6616..9365
                     /protein_domains="PF00672"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327467"
                     /pseudo=False
                     /translation="VSTTEVDAPARQAPPPSRGGIRGFADRWPFRRKLNLLVGIPLAVV
                     AVLLAYLVVDQVGQSTSASDAARLVRNSAQVATLVDRVEAEHQQAILLSVRFEAVDGGA
                     KPSLAGYRTAQQAVTQQVEKVRDAFGDQLPSTEAQALREVEGLTSLRETIEQGYLPADN
                     IDPAYTNASKGLIDGLGLDRNESLAATFTGNLLDSLLRADAAHSSFETSVFSARTGDTN
                     ALIEFINAVGAYELYSHQAERFARFASEEQTDRLGGIEHNSAQATITQHYAELQIDPSG
                     LSAQSPAQISKALSAALADYPDYRDQSATRLKITASLIGDIADRADEASGDASLRAALL
                     LAIGLIGFVLWIAFSVVVRRSVVRPVMALTGAAQEVAEVAGRELARVADDDAEDVGPPK
                     LREMPVTANDEIGTLAEVFNRVQTTSIALLERQVLSRRNVAEMFGNVGRRVSNLTTRQL
                     ALIDAVERGETDPALLERLYSIDHIAVRLRRNADSLMLLAGIRETVLDSGPTELTNVVR
                     AALGQIEGFQRVRLQARTEIMVEPDIIGDLTLMVAELLENAVSFSPAGSPVEVAVRDAS
                     VEDGSGASIVIADHGLGMSSERIAEENARLIRRERLDLVPTKVLGLFVVGTLARRWEVD
                     VTLSRTPGGGVTAEVTVPSSLLLTMSPVGSPASGGSPTKDPTPVGGGAAPDTWAGRDSA
                     PAGSTDRVAHDSATTLGLPERDSTTSAPVRAAWDAVGPGSGIGGATERGDSAVTRNGTA
                     PGPANTPSWAVQDDSAVDHVSGRRQPTGVEEDTGLSDHAPADGRPDPLPRRVPKREATE
                     PEAPFIPKARIETPPAPTTVSAEDGATRPLRRRVRGATLHTTADAQQSARQAPRPADAD
                     AVRDALDEFEAAVERANRDSTPAGTGVRTTPDPQDQNHLPEGAEQ*"
     CDS             9363..9838
                     /protein_domains="PF03259"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327468"
                     /pseudo=False
                     /translation="VSTSTGDTPTGSTTPTDLQAAAADFNWLLNRFATETAGVVDAIAV
                     SSDGLLIAVSELRERAHSERLAAIVSGITSLAAGASGNYGLGGLNKVIIDLEGGHVIVS
                     AIGSGAVLGVVADKEAKLGNIAYEMTLFANRAGAALSPQLVLELKNTVGVPSKR*"
     CDS             9879..10321
                     /protein_domains="PF05331"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327469"
                     /pseudo=False
                     /translation="MTDGRAPAGEDGTQRAGQAPVGPASAVRPFLVTAGRVAPTAAVGR
                     PVPVETQVVATAEGLAVLDSLSFEQHDIVAACRVPQSIAELAARLRLHLNVVRVLAEDL
                     RAAGQLAVHVPDSGVTHDATVLRRVIDALRAIPDSRGAVRDTD*"
     CDS             10309..10910
                     /protein_domains="PF03029"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327470"
                     /pseudo=False
                     /translation="VTPTEPATRGTAAPVAAVRPPLPVKMVIAGGFGVGKTTAVGAISE
                     IEPLTTEAAITEVAAGVDDLSHTPRKTTTTVAMDFGCLTIDPTLKLYLFGTPGQERFGF
                     MWDDIVEGAVGGLVIVDTRRLDDCYAAVDYFEHRQIPFAVAVNAFDGKIEHTLEEVRWA
                     LDVAEPVPVVVFDARERGSVRDALLVVLELALARSQA*"
     CDS             complement(10974..11641)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327471"
                     /pseudo=False
                     /translation="VNVLHYVNDFFSNSAHWHGYDGIPTRLREHIQYSLTALAIAAAIG
                     LPIGLLTGHTGRGGNSLALIATAARALPSFGLLVLMFVLLGLGHLPVMIPLVVLAVPPI
                     LVTTYEAMRSVDPSPVDAARGMGMAEPRILFQVELPVALPLILSGLRSAAIQIVSTATI
                     AAYVSLGGLGRYIVDGLYQRNYEKVVGGATLVAILALITLGLFWAINRFTVSAGVRRGA
                     *"
     CDS             complement(11639..12354)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327472"
                     /pseudo=False
                     /translation="MNGFFDIPSDLQNTYWGLVGLHLREALIPVLAGLLVALPIAQLCV
                     RLRWLYPPVLWITTVLYAIPSLAFFVVLIDYTGQTETTVMIPLAVYSLVVFVPAIVDGV
                     RSVPQETLDAATAMGLGPIRRYVQVQLPIAAPAIIAGLRVATVSSISLVSVGMLIGNQG
                     GLGNLLNDGMIYHQPRLIWLSVIGTAVLAILADALLVVIRLVITPWMPRGGRKTRPVDE
                     PARPEPAAPALEDAVR*"
     CDS             complement(12352..13481)
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327473"
                     /pseudo=False
                     /translation="LIRIDSVTKRYPDGTVAVDRLSLEIPDRSITVLVGPSGCGKTTTL
                     RMINRMIEPTEGTILIDGKDVMKQPVNTLRRSMGYVIQNAGLFQHRTIIDNIATVPRLL
                     GWSKDKARERARELMGRVGLDASLAKRYPYQLSGGQQQRVGVARALAADPPVLLMDEPF
                     SAVDPVVRKGLQDELLRIQEELGKTIVFVTHDIDEAVKIGTMVAVMRTGGKLAQFAPPA
                     ELLSRPADPFVEDFLGADRGIRRLSFFSSAGLDLLTTPIVAVDATAEQIAARTTPDAPY
                     LLVTDLDGKPLGWSEPGALAAGGIDPARLVSHGRPFVHGKESLRAALDGAVLSPTGWAV
                     AVDTEGRVAGVVSQQTIGEAIRAAHAEGRADAKVAG*"
     CDS             13750..14630
                     /protein_domains="PF00535"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327474"
                     /pseudo=False
                     /translation="MVTAMNETNAGGVRRRSVEVVVPVFNEAHVLADSVGTLHAHLEES
                     FPFPFRITIADNASTDATWRVATSLTESLPHVHAVRLAAKGRGRALKQVWSESTADVVA
                     YMDVDLSTGLEGFLPLVAPLLSGHSDLAIGSRLHRQSAVVRGPKREFVSRSYNLLLKLG
                     LAARFSDAQCGFKAVRTDVFRALAPHIEDTAWFFDTELLVLAQRNRLRIHEVPVDWVDD
                     PDSRVDIVATALDDLRGVRRMLRATVTGRTRVTDVPRRTGTPHVPAARESLDVPPTGAH
                     ASSRSDHLEYAS*"
     CDS             14628..16741
                     /protein_domains="PF13231"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2327475"
                     /pseudo=False
                     /translation="MTTLAPPPAPAAQDGRHRAAAPPVPRIRRLFTGAPEDPRWARPAL
                     WAILVLATLLYAWNLSSITGNTFYNAAVYSGTKSWKAFFFGALDSGSFITVDKPPFALW
                     VMGLSARVLGFGTWQLMLPMVAVGTGSVALLYRMVKRDFGAVAGTISALVLTLTPITVA
                     INRDTNPDPILVFLMLLGAAALMKAVRTGRLMPLVWAGVAIGFAFNTKMMQAYVVLPAF
                     FLVYLWATRISLSRRIRNLAVGTVALIASSAWWMVVVDLIPASSRPYIGGSTDNTVWDL
                     VIGYNGFGRIFGASSSVGSQGNGASFGGEAGLYRLFNSIMGGQISWLIPFAAIALIGGL
                     VLRGRAPRTDAKRAALMLWGGWFVLHYLTFALAEGTFHPYYVTAMAPGIAALAGAGGVM
                     LYRAFKDGSAAKWGWVLPAAIAVSSVWAIVLLQRVSGSGTLYTVAEVVAGVAGAAAVIG
                     LLVGRFTRRQRLTGIAALAAIVALLAGPAAYSVSAATSGTNGTNPTAGPSTGGGMGGGG
                     GMGGGQRPSGNGGPDGGSSSGTSGSGGQSTGTPPSGSAPSGSAPSGSGSSSSGSSSEAE
                     SGSKAGTAGATGGGMGGGSVSSAEITYLKKHQDGATWLVAVATDQTASSIILESGQPVI
                     SMGGWSGSDNAMTLAKLKSLVKSGKLHYIVVSSDGGQGTNSEISTWVKKHGTAVSDYSG
                     LYRLDASDVS*"
ORIGIN
        1 atgacagccg tactgcagac cacgcccacg gccgagccgg tggccaacta ccgcctgtcg
       61 ctccgacgct tcacgcgcaa caagctggcc gtcgccggac tcaccgtggt cgtcctcttc
      121 cttctcttct gcttcgtcgg gcctctcctc tactccaccg accagaccca caccgacctc
      181 acccaggtca acctcggccc gagcggctcc cattggctgg ggaccgatgc cgtcgggcac
      241 gacgaactcg ggcggttgat gtacggcggg aaggtctcga tgctcgtcgg gctggcggcc
      301 gggatcctgg ccaccgtcat cggcacgctc tggggcgcca ccgcggggta cgccggcggt
      361 tggctggacg cggtgatgat gcggatcgtg gatgccggca tcgccatccc cgcgttgttc
      421 atcctgctgg tcgtctccgc gatcacgacc ccggacacgc tcggcctgat cgtcgtgctg
      481 ggcttggtgt cctggctggt gccgtcccgg ctggtgcggg ccgagacact cacgctcaag
      541 agccgggact acgtgctgac actgcgcgcg accggcggca cccacggccg ggccatccgg
      601 cggcacatcc tgccgaactc ggtgtcgacg atcgtcgtcg cggccacctt ccaggtcgcc
      661 gacgcgatcc tgctcgtcgc gtacgtctcg tatctcggcc tgggggtcca gccgccgaag
      721 accgactggg gcggcatgct gtccgccggg ctgacggcgg cgtactccgg gcgctggtgg
      781 ctgatcgttc cgccgggtct cgcgatcatc ctcgtcgtgt gcgcgttcaa cgcgatcggc
      841 gacgggctgc gcgacgcctt cgacgtgagg ggccgagggt gacggaaaca gaggggacga
      901 aggtggcgaa cattctggag gtcgaggatc tcggggtcac cttctccacc gacaccggtg
      961 acgtgcccgc cgtgcgcgag gtgtcgttgc acgtccggcc cggcgagacg ctggcgctgg
     1021 tcggcgagtc cgggtcgggg aagtccacgg tggcgctcgc ggcgatgggg ctgctgccgt
     1081 ccaacgctcg tgcgtcgggg cgggtttcgg tcgacggcac acaggtcgtc ggggccggtg
     1141 aggccgaact ggcccggctg cgcggccgta ccgcgtcgat ggtgttccag gaaccggcca
     1201 ccgcactcga tccgctgacc cgggtcggtg cgcagatcgc cgaagtcgta cgcaatcacc
     1261 gggccgtctc acgtgccgag gccgcccgcg aggccgtcga actgctgcgc agggtcggca
     1321 ttcccgagcc ggagcggcgg gcgtcggcgt ttccgttcca gctgtcgggc gggcagcggc
     1381 agcgggtcgt catcgcgatg gcgatcgcca actcaccggg cctgctgatc gcggacgagc
     1441 cgacgaccgc cctcgacgtc accgtgcagg ccgagatcct ggatctgctc cgcgcgttgg
     1501 ccgccgactc cggcaccggt gtgctgctgg tgacgcacaa catgggcgtg gtggccgact
     1561 tcgccgaccg ggtcgccgtg atgctgagcg gcgaggtcgt ggagagcggg ccggtcgagc
     1621 aggtgctgct gcagccgcaa cacgagtaca cgcagcggct gttggaggcc gttccgcggc
     1681 tggccgtgga ggtgccggtg gtggaggaat cggccgtgga ggcatcggcg gttgcggacg
     1741 tgccccggga ggtggtgggt gcgccggtgg tcgcggaggg cgagccgccg gccccggagg
     1801 gggacgccgt ggtcgaactc cgggatgtct ccgtgcggtt cgggcgtggt ccgggggccg
     1861 tgcaggccct tcaggacgtg tcgctcaccg tgcggcccgg cgagacggtc gggctggtgg
     1921 gcgagtccgg gtccggcaag tcgacggcgg cgcgcgtggc gttggggctg gtcgcgccga
     1981 gcggcgggac cgtgtctctg ttcgggcggg agctcggccg gacccgcggt cgtgcacgtc
     2041 gggccctgct gtccggggtc ggtgtggtgc tccaggaccc ggtggcctcg ctggacgccc
     2101 ggatgagtgt cggggagtgc gtggccgagc cgctgcggat gcatcgccgg ggtctgtcgg
     2161 cggccgagcg gcggacgttg gtcgcggaga tgctggaacg ggtgcggctg ccgcgggagt
     2221 tggcggggcg cgggccccgc gagctgtccg gcgggcagcg gcaacgggtc agtctcgcgc
     2281 gggcgttggt gcttgaaccg aggctgttgg tcgcggacga gccgaccagt gcgctggacg
     2341 tgagtgtgca gcggacggtg cttgaggtga tcgcggagtt gcagggcgag ctcgggttcg
     2401 cgtgtctctt cgtgtcgcac gacctcgcgg tggtccagcg gttcgcccag cgggtcgtcg
     2461 tcatgcgggc cgggcgcgtc gaggaggagg ggccgaccat gaccacgctg ctgcgtccgg
     2521 agacggagta cacgcgccgg ctcatcgcgg ccgtgccggt gccggacccg gtcgtccagc
     2581 gccgccgccg ggaagccctg cggacggggg tcaccgcgtg acgcgcgctc ccgaggtggt
     2641 cgcgggcgtc gacatcggcg gcacgaccac ccaagtcgtg ctgtgcgccg ctgacttcgg
     2701 catcggcgac cgcctggagg tgcccactcc agcggaccgg ggcggggcgg cgatggtcgg
     2761 cgccgcactg gacgccgtac gactgctgct tgagcgaact cccgtgcggc tgctgggagt
     2821 tggcgtcggc gcggccgggc tggtggacgt gcgggccggg cggatcctgg tggccagcga
     2881 ctccttccgg gactgggccg ggttcgaggt gacggcggcg gtcgaacggg cgctgggtgt
     2941 accggcgttc ctcgacaacg acgtcaacgc gttcctgcgc ggtgaggcgg cggcaggcgc
     3001 ggtcgcgggc gaaccgtatg tgctcggcat gaccttgggc accggggtcg gcggggcgct
     3061 gtggctggat ggcgccctgt acgagggccc gcacggggcg gccggcgaga tcgggcacgt
     3121 gcccggcttc ggcgagctgc cgtgcacctg cggcgggcgc ggccacctgg agacgctggc
     3181 gtcgggccgc tcgatcgcgg cccggtacgg cgagcgcacc ggccgggacc tgaccgccca
     3241 cgaggtcgcc gacgcggcgg cccggggcga ggcggacgcc ctcgcggtct acgcggcggc
     3301 gggcgccggt gtggcccggg cgctgctggt cacggccggt ctgctggacg tcacgacgtg
     3361 cgtgatcggc gggggtgtca gccggtcgtg gtcgctgctg gagcccgcga tacgccggac
     3421 gctgaccgcc gagccacccg tcagcggccg tgccctgcgg gtgctgcccg ccgctctcgg
     3481 cggtgacgcg gtggcggtcg gggcggcggc tcgggcgtgg gcggagctgg gtgcggtggg
     3541 ggcggcggag gagcgggcgc gggcgtaggc cccgcccgcc cccgtggcgt atccgtgtcc
     3601 cgcctgtggt gccgttgtgg atcgacgatc gaatccggcc aagcgtgacc gggtgattga
     3661 cgctcacgcg tcacatccct accttctgat cggtttaccg aacctcgttc gatataccga
     3721 caattgggca ccccccgcac gcccccagga gagccagatg aacgccagac cgcaccccgg
     3781 tccccacccc gccgcacacc cctcccgccg cctgttcctc ggcatggcgg cgaccgtgcc
     3841 gctcgccgcc accggcgccc tgacgctcgg tgccggcacc gcccacgcag ccgactcggc
     3901 gtacgtgatg gcctacttca ccgagtcacc ggacatgctc gccgccaact acggcctgca
     3961 cctggccgtc agcaccgacg gcctgcagtg gaccccgctc aaccagaacg cgcccgtggc
     4021 caccccgacc gccggctccc tcggcctgcg cgaccccttc atcctgcgca agcaggacgg
     4081 caccttcgtg gtgctcgcca ccgacctcaa cggcaccgac tggacgtacg tcagccagta
     4141 cctccacgtc tgggactccg ccgacctgcg taccttcacc ggttaccggc ggatgaaggt
     4201 gcacgacctg gacacccacg cctgggcgcc cgaggcgttc tgggacgcgg ggcgcggcca
     4261 gtacgcggtg atctactccg cggtcaactc cagtggccac aacgtgatca tggtgaacta
     4321 caccaccgac ttcgtgaccg ccggctcccc gcaggtcttc ttcgaccccg gctacgacgt
     4381 catcgacggg gacatggccg tcggtgtggg cggctacaac tacctgtact tcaagaagaa
     4441 ctcgaccctg gtcggcgccc gctccacctc actggacccg ggcagcttca cggagttcag
     4501 caccgccgtc tcgcacaacg gcaccgaggc accgacgctg gtcaagcccc tcacgtcgag
     4561 ctcgacctgg tacttgtggg gagacacctg gtcgccgaac ggtgtcttct acgcctggca
     4621 gacgagcagc ctcgccgccg gcacctggac cgcgctcgac cagaagacgt acacccagcc
     4681 tctgaactcc aagcactgcg gcatccagcc gatcaccgcg gcccagtaca gcaacctggt
     4741 cgccaagtgg ggcacgcccg cctggaaccg gctgaagtcc tacaactacc cggcccggta
     4801 cgtccggcac agcaactacg tcggccgcat agacgagtac gccttcgacc cgtacgccga
     4861 ctcgcagtgg aagctggtcc ccggtctcgc cgacagcgcg ggggtgtcct tccagtcggt
     4921 gaactacccg accaggtatc tgcggcacta cgactacgcg ctccgactcg acgtcaacga
     4981 cggcacgtcg acgttcgcgg gtgacgcgac cttctaccgc acggcgggcc tcgccgacgc
     5041 gagctgggcc tcgttccgct cgtacaacaa cccgacccgc tacatccggc actccaacta
     5101 cgtcctgcgc atcgacccgg tctcgacgtc gaccgagcag caggacgcga ccttctacgt
     5161 cggctactga gacgtcgggt acgcagacac gggccgctga gccgcgggca cgacgaaggc
     5221 gggcgcccct cccggaaagg cccggagagg gacgcccgct tcacagctcc ggggatcagc
     5281 ccaggccgac cgtcttcagc caggccttcg cgacgtccag cgggtccttg ttgtcgagct
     5341 ggacctgcga gtccaggtcg agcagggcct tggtgtcgag cttggccgag accgcgttga
     5401 gcgcggcgac gccctccgag gacaggccgc tcttgtagac caggggctgc acgttctcga
     5461 agccgaagag gttctccggg tcctggagga cgacgtgctt ctcctggacg atggtcgggt
     5521 ccgtggtgaa gaggtccgcc gcctgcacgg tgttcttctt cagcgccgcc tgggtcagcg
     5581 ggccgcccgc gtccagcgcc ttgaaggact tgaactccag gccgtacacc gacttcaggc
     5641 cgaccaggcc ctgctggcgg gtctggaact ccggcgaggc gccgatcgac aggtccttcg
     5701 cgatgtcctt gaggtccgcg atgctggact cggcggtcag gttgtacttc ttcgcggtcg
     5761 cggcgttgac cgtgaccgag tccttgtcct gcgccgaggc cgggtcgagc agcgtcagct
     5821 tggtgtccag cttggcgtcg atggcggccg tggtggcctc caccgtcttc ggggtggcct
     5881 tcgggtcgag gtaggccagc agtgcgccgt tgtactcggg cagcacggtg atggagccgt
     5941 tcttcagcag gccgtaggtg gtctcacggc tgccgatgtt cggcttgtag gtgaccttga
     6001 tgcccttcgc cttgagcgcc tcgccgtaga tgtcggcgat caggatgctc tcggcgaagt
     6061 tgttggatcc gacgacgacg gtcttgccgt ccgacttgtc cccggccagg gggtcggact
     6121 tgtcgtcgga agaagaggaa catcccgcca gcagggccgt ggtggcggcg agcgctacgg
     6181 cggccgcggg atgaatcctg aaggacctgc tgcgtggggc gttggaagtc acgattcccg
     6241 ttccggactc tggggattgg tgtgaagcga gcgctgcaac tgatccaatc cagcctgttc
     6301 tcacccagtc aagagcagcc tggtcaccga ttggactcaa tgcgtgatcg cttacgcctc
     6361 aatgcgtgat cacctgtgaa ggaacggcga acggacgggt gaggaaccgg aggctctttg
     6421 taacggattc ttgacgtagg gcgacgcgct tgatcgttca aagaggcggt agtctcacgg
     6481 cagttggcgt cggtcacagc ggtgtgcggg ggccgcttcg gtgtcttcga caccatttcc
     6541 ggggtccggc ccatcgatca gaatcggtca cgcgcatcga cgcgcccgat gagaacatgc
     6601 acgaaggagg accggtgtcc acgaccgaag tggacgcgcc cgcccggcag gccccgccgc
     6661 cgtcgagggg cggtattcgg ggcttcgccg accggtggcc gttcaggcgc aaactcaacc
     6721 tcctggtcgg catcccactc gccgtggtgg ccgtcctgct cgcctatctc gtcgtcgacc
     6781 aggtgggcca gtcgacctcc gcgtccgacg cggcgcggct ggtgcgcaac agcgcccagg
     6841 tcgccacgct ggtggaccgg gtcgaggccg agcaccagca ggccatcctg ctctccgtgc
     6901 ggttcgaggc cgtggacggg ggcgccaagc cctcgctggc cggctaccgg acggcgcagc
     6961 aggcggtgac ccagcaggtc gagaaggtgc gcgacgcctt cggcgaccag ctgccgagca
     7021 ccgaggcgca ggcgctgcgc gaggtcgagg gcctgaccag cctgcgcgag acgatcgagc
     7081 agggctatct gcccgccgac aacatcgacc cggcgtacac caacgcctcc aagggtctga
     7141 tcgacggcct gggcctggac cgcaacgagt cgctcgccgc gaccttcacc ggcaacctgc
     7201 tggactcgct gctgcgcgcc gacgccgccc acagctcctt cgagaccagc gtgttctccg
     7261 cgcgcaccgg cgacacgaac gcgctgatcg agttcatcaa cgcggtcggc gcctacgagc
     7321 tctacagcca ccaggcggag cgcttcgcgc ggttcgcctc ggaggagcag accgaccggc
     7381 tgggcggcat cgagcacaac tccgcgcagg cgacgatcac ccagcactac gccgagctgc
     7441 agatcgaccc gagcgggctg tcggcgcagt cgccggcgca gatcagcaag gcgctgtcgg
     7501 ccgcgctggc cgactacccc gactaccgcg accagtccgc gacccggctg aagatcaccg
     7561 cctcgctcat cggcgacatc gccgaccggg ccgacgaggc ctccggcgac gcctcgctgc
     7621 gcgccgcgct gctgctcgcc atcggtctga tcggcttcgt cctgtggatc gccttctccg
     7681 tggtggtacg ccgctcggtg gtccgtccgg tgatggccct gaccggcgcc gcgcaggagg
     7741 tcgccgaggt ggccgggcgc gagctggccc gggtggccga cgacgacgcc gaggacgtcg
     7801 ggccgccgaa gctgcgcgag atgccggtga cggcgaacga cgagatcggc acgctggccg
     7861 aggtgttcaa ccgggtgcag accacctcga tcgccctcct ggagcgtcag gtgctcagcc
     7921 gccgcaacgt cgccgagatg ttcggcaacg tcggccgccg ggtcagcaac ctcaccaccc
     7981 gccagctggc cctgatcgac gcggtggagc gcggcgagac ggatccggcg ctccttgaac
     8041 gcctctactc catcgaccac atcgccgtgc gtctgcgccg caacgccgac tccctgatgc
     8101 tgctggccgg catccgcgag accgtcctgg actccggacc caccgagctc accaacgtcg
     8161 tacgcgccgc gctcggccag atcgagggct tccagcgggt acggctgcag gcccgcaccg
     8221 agatcatggt ggagccggac atcatcggcg acctgaccct gatggtggcc gagctcctgg
     8281 agaacgcggt gtcgttctcg ccggccggca gtccggtcga ggtcgccgta cgggacgcct
     8341 ccgtcgagga cggttcgggt gcctcgatcg tcatcgcgga ccacggtctg ggcatgagca
     8401 gcgagcggat cgccgaggag aacgcccggc tgatccgccg cgagcgcctg gacctcgtac
     8461 cgacgaaggt gctcggcctg ttcgtggtcg gcaccctggc ccgccgctgg gaggtcgacg
     8521 tcaccctctc ccgcaccccg ggcggcggcg tcacggccga ggtgacggtc ccctcgtccc
     8581 tgctgctgac gatgagcccc gtcggatcgc cggcctccgg cggttcgccg acgaaggacc
     8641 cgacgccggt cgggggcggg gccgcgccgg acacctgggc cggaagggac agcgccccgg
     8701 cgggttccac cgaccgcgtc gcacacgact cggcgaccac cctcggcctg cccgagcggg
     8761 actcgacgac gtccgctccc gtgcgggccg cgtgggacgc ggtcggtccc ggcagcggca
     8821 tcggcggcgc gaccgagcgg ggcgactccg cggtcacccg caacgggacc gcccccggcc
     8881 cggcgaacac ccccagctgg gccgttcagg acgactcggc cgtcgatcac gtgtcaggcc
     8941 ggcggcagcc aaccggcgtc gaggaggaca ccggattgtc ggatcacgcc ccggccgacg
     9001 ggcgaccgga cccgctcccc cgtcgcgtcc ccaagcggga ggcgacggag cccgaggccc
     9061 cgttcattcc caaggcccgt atcgagactc ccccggcgcc gacaacggtg tccgccgagg
     9121 acggcgcgac gcgcccgctg cgccgccgcg ttcgcggggc gacgctgcac acgaccgccg
     9181 acgcccagca gtcggcgcgg caggcccccc ggcccgccga cgcggacgcc gtccgtgacg
     9241 cgctcgacga gttcgaggcg gcggtggagc gggccaaccg cgacagcacc cccgccggga
     9301 ccggcgtacg cacgaccccc gatccgcaag accagaacca cctcccggaa ggagcggagc
     9361 agtgagtacg tcgacaggtg acactccgac gggaagcacc acgccgaccg atctgcaggc
     9421 cgccgcagct gatttcaact ggctgctcaa ccgattcgcc accgagaccg cgggcgtcgt
     9481 ggacgccatc gcggtgtcct ccgacgggct gctgatcgcc gtgtcggagc tgcgcgagcg
     9541 ggcccactcc gagcggctgg cggccatcgt ctcgggcatc accagcctgg ccgccggagc
     9601 ctccggcaac tacggtctgg gcggtctgaa caaggtcatc atcgacctgg agggcggtca
     9661 cgtcatcgtc tccgcgatcg gcagcggcgc cgtgctcggc gtggtcgccg acaaggaggc
     9721 caagctcggc aacatcgcct acgagatgac gctgttcgcc aaccgggccg gggccgcgct
     9781 cagcccccag ctcgtgctcg aactgaagaa caccgtcggc gtcccgtcga agcgctgacc
     9841 cggtcgccga ccggtccgaa gaggaggacg acaactcatg acggacggcc gtgcaccggc
     9901 cggcgaggac ggtacgcagc gagcgggcca ggccccggtc gggcccgcct ccgccgtacg
     9961 gccgttcctg gtcaccgcgg ggcgggtggc gcccaccgcg gcggtcggcc gtccggtgcc
    10021 cgtggagacc caggtggtgg ccaccgccga gggactcgcg gtgctcgact cgctctcctt
    10081 cgagcagcac gacatcgtcg ccgcctgccg ggtgccgcag tccatcgccg aactggcggc
    10141 ccggctgcgg ctgcacctca acgtcgtccg ggtcctcgcc gaggacctgc gtgccgccgg
    10201 gcagctggcg gtgcacgttc ccgactccgg cgtcacgcat gacgccaccg tcctgcgcag
    10261 ggtcatcgac gccctgcgcg ccatacccga ctcccgaggg gcagtccgtg acaccgactg
    10321 aaccggccac gcgcggcacg gccgctccgg tggccgccgt acgcccgccg ctcccggtga
    10381 agatggtgat cgccggcggt ttcggcgtgg gcaagaccac cgccgtcggc gcgatctccg
    10441 agatcgagcc gctgaccacc gaggccgcca tcaccgaggt cgccgcgggc gtggacgacc
    10501 tcagccacac cccgcgcaag accaccacca cggtggccat ggacttcggc tgtctcacca
    10561 tcgacccgac cctgaagctg tacctgttcg gcacgcccgg gcaggagcgg ttcgggttca
    10621 tgtgggacga catcgtggag ggcgcggtcg gcggactcgt catcgtcgac acccgccgcc
    10681 tcgacgactg ctacgcggcc gtcgactact tcgagcaccg gcagatcccg ttcgcggtcg
    10741 ccgtcaacgc cttcgacggg aagatagagc acacgctgga ggaggtccgc tgggcgctcg
    10801 acgtcgccga gcccgtcccg gtggtggtct tcgacgcccg tgagcgcggc tcggtccgcg
    10861 acgccctgct cgtcgtactg gaactggcgc tggcccgttc gcaggcgtag ccgcacgaga
    10921 agcgggccgg gagcggacgt actgtccgct cccggcccgc tctcgtgtgc cgtcaggcgc
    10981 cgcgtcgtac gcccgcggag accgtgaagc ggttgatcgc ccagaacagc ccgagcgtga
    11041 tcagggcgag gatcgccacc agggtggcgc cgccgacgac cttctcgtag ttgcgctggt
    11101 agaggccgtc gacgatgtag cggccgaggc ccccgaggct gacgtaggcg gcgatggtgg
    11161 ccgtcgagac gatctggatg gccgccgagc gcagtccgct gaggatcagc gggagcgcga
    11221 ccgggagctc gacctggaac aggatccgcg gctccgccat gcccatgccg cgggccgcgt
    11281 ccaccgggga cgggtcgacg gaccgcatcg cctcgtacgt cgtcaccagg atcggcggga
    11341 cggcgaggac gaccaggggg atcatcacgg gcaggtggcc gaggccgagc agcacgaaca
    11401 tcagcaccag cagaccgaag ctgggcaggg cgcgggcggc ggtggcgatg agcgccaggg
    11461 agttgccgcc gcgtccggtg tggccggtga gcaggccgat gggcaggccg atggcggcgg
    11521 cgatggcgag ggcggtcagc gagtactgga tgtgctcgcg cagccgggtg gggatgccgt
    11581 cgtagccgtg ccagtgggcg ctgttgctga agaagtcgtt gacgtagtgc agtacgttca
    11641 ccggaccgcg tcctccaggg cgggcgcggc cggttcgggc cgggccggtt cgtcgacggg
    11701 tcgggtcttg cggccgccgc gcggcatcca gggcgtgatg accagccgga tgacgaccag
    11761 gagggcgtcc gcgaggatcg cgagtacggc ggtgccgatc acggacagcc agatcaggcg
    11821 tggctggtgg tagatcatgc cgtcgttgag caggttgccg aggccgccct ggttgccgat
    11881 cagcatgccg acgctgacca gcgagatgct cgacacggtc gccacccgca ggcccgcgat
    11941 gatcgcgggc gcggcgatcg gcagctgcac ctggacgtag cggcggatcg gccccaggcc
    12001 catggcggtg gccgcgtcga gggtctcctg cggcaccgag cggacgccgt cgacgatcgc
    12061 cggcacgaac acgaccaggc tgtagacggc cagcgggatc atcaccgtgg tctcggtctg
    12121 gccggtgtag tcgatgagga cgacgaagaa ggcgagcgag gggatcgcgt agagcacggt
    12181 cgtgatccac agcaccggcg ggtagagcca gcgcagccgc acacacagct gggcgatcgg
    12241 cagcgccacg agcagaccgg ccaggaccgg gatcagggcc tcgcgcagat gcagtccgac
    12301 caggccccag taggtgttct ggaggtcgct gggtatgtcg aagaaaccgt tcatccggcg
    12361 accttcgcgt cggcgcggcc ctcggcgtgg gcggcgcgga tggcctcgcc gatggtctgc
    12421 tgcgagacga cgccggccac ccggccctcg gtgtcgaccg cgacggccca gccggtcggc
    12481 gagagcaccg cgccgtcgag cgcggcgcgc agcgactcct tgccgtgcac gaagggcctg
    12541 ccgtgcgaca cgagccgcgc ggggtcgatc cctccggcgg ccagggcgcc cggctcgctc
    12601 cagccgagcg gcttgccgtc caggtcggtg acgaggaggt agggcgcgtc cggggtggtg
    12661 cgggcggcga tctgctcggc ggtggcgtcg acggccacga tcggcgtggt cagcaggtcc
    12721 aggccggcgg aggagaagaa ggagagccgg cggatgccgc ggtccgcgcc gaggaagtcc
    12781 tcgacgaacg ggtcggcggg cctggacagc agctcggcgg gcggcgcgaa ctgggcgagc
    12841 ttgccgccgg tgcgcatcac ggcgaccatc gtgccgatct tgacggcctc gtcgatgtcg
    12901 tgcgtgacga agacgatggt cttgcccaac tcctcctgga tgcgcaggag ttcgtcctgg
    12961 aggcccttgc ggaccacggg gtcgacggcc gagaagggct cgtccatgag gaggaccggc
    13021 gggtcggcgg cgagcgcccg ggccacgccg acgcgctgct gctgaccgcc ggagagctgg
    13081 taggggtagc gcttggcgag cgaggcgtcg aggccgaccc ggcccatcag ctcccgggcc
    13141 cgctcccggg ccttgtcctt gctccagccc agcagccggg gcacggtcgc tatgttgtcg
    13201 atgatcgtgc ggtgctggaa gagcccggcg ttctggatca cgtaacccat cgaccggcgc
    13261 agggtgttga ccggctgctt catgacgtct ttgccgtcga tgaggatggt gccctcggtc
    13321 ggctcgatca tccggttgat catgcgcagg gtcgtggtct tgccgcagcc cgaaggtccg
    13381 acgaggacgg tgatcgagcg gtcgggtatc tccaaggaga ggcgatcgac cgccaccgtg
    13441 ccgtccgggt accgcttggt gactgaatct atccgtatca aaacgccgaa tacccttcgg
    13501 gactggcaga aaatgcccgc tttggccaac ggtcacaggc cgttgccggg agagtctaaa
    13561 ccgtccgggt tttgacgtat cgcctggagc gggcgagatt catccgcccg ttacgaacag
    13621 ggccgccgac cccgccgcag ggccggattc tgggggtccg tggtcaccgc gctgtgtcct
    13681 gcctgtgagt ccgctgattc tcactctccg ctcagaggcc gctcagggat cccccagaca
    13741 gcgccctgat ggtcactgcc atgaacgaaa cgaacgcggg aggcgtccga cgccggtcgg
    13801 tcgaggtggt ggtgccggtc ttcaacgagg cgcacgtcct cgccgacagt gtcggcaccc
    13861 tccacgcaca cctcgaagag tccttcccgt tcccgttccg gatcacgatc gcggacaacg
    13921 cgagcacgga cgccacctgg cgggtggcga cctcgctcac cgagtcgctg ccgcacgtgc
    13981 acgccgtacg gctggcggcc aagggccggg gccgggcgct gaagcaggtg tggagcgaat
    14041 cgacggcgga cgtcgtcgcc tacatggacg tcgacctctc caccggtctt gagggcttcc
    14101 tccccctggt cgccccgctc ctgtccgggc acagcgacct cgcgatcggc agccggctgc
    14161 accggcagtc ggccgtggtg cgcggcccga aacgggagtt cgtgtcccgc tcgtacaacc
    14221 tcctcctcaa gctcggtctg gcggcgcgtt tctcggatgc ccagtgcggg ttcaaggcgg
    14281 tgcgcaccga cgtgttccgc gcgctcgccc cgcacatcga ggacaccgcc tggttcttcg
    14341 acaccgagct gctggtcctg gcccagcgca accggctgcg catccacgag gtgccggtcg
    14401 actgggtcga cgaccccgac agccgcgtgg acatcgtcgc caccgccctc gacgacctca
    14461 ggggcgtacg gcgcatgctg cgcgccaccg tgaccggccg cacccgggtc accgacgtac
    14521 cccggcggac cggcaccccc cacgtgccgg ccgcccgcga gtccctcgac gttccgccca
    14581 ccggggcgca cgcctcttcc cgctcggacc acctggagta cgcgtcatga cgaccctcgc
    14641 cccgcctccc gcgcccgcgg cccaggacgg ccgccaccgc gccgcggcac cgcccgtccc
    14701 ccggatcaga aggctgttca ccggcgcccc cgaggacccg cgctgggccc gccccgccct
    14761 gtgggcgatc ctggtgctgg ccacgctcct gtacgcctgg aacctctcct ccatcaccgg
    14821 caacaccttc tacaacgcgg ccgtctactc cggcaccaag agctggaagg cgttcttctt
    14881 cggcgcgctg gactccggca gcttcatcac ggtcgacaaa ccgccgttcg cgctgtgggt
    14941 gatgggcctg tcggcccgcg tcctcggctt cggcacctgg cagttgatgc tgccgatggt
    15001 cgcggtcggc acgggctcgg tcgccctcct gtaccgcatg gtcaagcggg acttcggcgc
    15061 ggtggcgggc acgatctccg ccctggtgct caccctcacg cccatcacgg tcgccatcaa
    15121 ccgcgacacc aaccccgacc cgatcctcgt cttcctgatg ctgctgggcg ccgccgccct
    15181 gatgaaggcc gtgcgcaccg gcaggctgat gccgctggtg tgggccgggg tcgcgatcgg
    15241 cttcgcgttc aacacgaaga tgatgcaggc gtacgtcgtc ctgcccgcgt tcttcctcgt
    15301 ctacctgtgg gccacgcgca tctccctgag ccgccgcatc cgcaacctgg ccgtcggcac
    15361 agtggcgttg atcgcctcca gcgcctggtg gatggtggtc gtcgacctga tccccgcctc
    15421 ctcccgcccc tacatcggcg gctcgaccga caacacggtc tgggacctgg tcatcggcta
    15481 caacggcttc ggccgtatct tcggggcgag ttcgtcggtc ggctcgcagg gcaacggcgc
    15541 gagcttcggc ggcgaggccg gtctctaccg gctgttcaac agcatcatgg gcggccagat
    15601 ctcctggctg atccccttcg cggcgatcgc cctcatcggc ggcctggtgc tgcgcggccg
    15661 ggcgccccgc acggacgcca agcgggcggc cctgatgctg tggggcggct ggttcgtcct
    15721 gcactacctg accttcgccc tcgccgaggg cacgttccac ccgtactacg tcaccgccat
    15781 ggcacccggc atcgcggcac tggccggcgc cggcggggtc atgctgtacc gcgccttcaa
    15841 ggacggctcg gcggcgaagt ggggctgggt gctgccggcc gcgatcgcgg tgagctcggt
    15901 gtgggcgatc gtcctgctcc agcgggtctc cggctccggg acgctctaca cggtcgcgga
    15961 ggtcgtggcc ggggtcgccg gtgcggccgc ggtgatcggc ctgctggtcg ggcggttcac
    16021 caggcggcag cggcttacgg ggatcgcggc actggcggcg atcgtggcgc tgctcgccgg
    16081 tcccgccgcg tactcggtgt cggcggcgac ctccggcacc aacggcacga acccgacggc
    16141 cggtccgagc accggtggcg ggatgggcgg cggcggtggc atgggcggcg gccagcggcc
    16201 cagcggcaac ggcggtcccg acggcgggag ttcgagcggc acgagcggct cgggcggtca
    16261 gtcgacgggg acgcctccgt cggggagcgc gccgtcgggg agcgcgccgt cgggcagcgg
    16321 gtcttcgagc agcggctcgt cgtccgaggc ggagtccggc agcaaggcgg gcaccgcggg
    16381 cgcgaccgga ggcggcatgg gcggtgggtc ggtctcctcc gcggagatca cgtacctcaa
    16441 gaagcaccag gacggcgcca cttggctggt ggcggtggcc accgaccaga ccgcgtcctc
    16501 gatcatcctg gagtccggtc agccggtgat ctccatgggc ggctggtccg gttccgacaa
    16561 cgcgatgacc ctggccaagc tcaagagcct ggtgaagtcg ggcaagttgc actacatcgt
    16621 cgtcagcagt gacggcggac agggcaccaa ctccgagatc tccacctggg tcaagaagca
    16681 cggcacggcg gtgagcgact acagcgggct gtaccgcctg gacgcctccg acgtcagctg
    16741 a
//
