LOCUS       reptomyces_RBGC_224142 17330 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_224142
VERSION     Streptomyces_RBGC_224142
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001514305.1
  ORGANISM  GCF_001514305.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..1275)
                     /protein_domains="PF02515"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420321"
                     /pseudo=False
                     /translation="MTTNSAYQPPTRSRPGGTTGQRPPSPRHTPGAFDGIKVLDAATLV
                     AGPMIATYMGEYGADVIKVEQPGSGDPIRQWGANKGDINLMWKSLGRNKRCVSLNLRVE
                     AGQELFRRLAAEIDVVILNARPSALERWGISYEDLASRNEGLVMIHVTGYGAGGPYSDK
                     AGFGTISEAMSGFAHITGEADGPPTLPGFMLADCTAAVHGAFAVSAALLHRERTGQGQL
                     IDLSLLEPLARFAEQATLTYDQLGKIPGRVGNKWAISVPRNTYKTGDGHWIALSGSAQS
                     VALKVFDAIGRPELREDPEYADPLRRIVNRDAVDDLIADWIRQRSLQTVMQQFDDHGVA
                     AGPVYNAQQLMADPHLKARGTFVPVKDEDLDEVRVQAPVARMSQTPGVIRYLGRSVGQD
                     NRDVLHELLGVGDEEFKRLDDGGAL*"
     CDS             complement(1385..2775)
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420322"
                     /pseudo=False
                     /translation="MTKDRRTEQPTEPAGPVTPGPATPAEPEVAASAYRIVARRLLPIM
                     CVCYFFSYLDRTSVSVAALTMNDALRISATAFGLGAGLFFLGYFIFEVPSNLIMFRVGA
                     RVWMARIMVTWGLVAVLQAFVWNEMSFYAIRILLGAAEAGFFPGMILYLTFWFPARQRA
                     RVVGLFFCAVPLSTALGAPLGGLLLKVNGLGLEGWQWLFILEGIPTVLLGVFLFSYLTD
                     RPDKAEWLPRPEKEWLTATLRAEATEIEAHHPQSELASLKDPRVLGLAAVYFTLVFGLY
                     GLSFWLPTIIKSSLGIEDNLTVTLLTAAPYAVGAIAIIAAGIMVDRLNQPARITAFFLA
                     AGGLALTVTAFATNPWVGYAGLFICAVAVISTFAGFWRLPTAFLTGAAAAAGIAAVNSL
                     GNIAGFVGPYWVGWLTDRTGHPKWGLVSIGALMILGTVLALRMSSVMRTGTQVKTGEGT
                     AAVTQ*"
     CDS             complement(2938..3743)
                     /protein_domains="PF13561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420323"
                     /pseudo=False
                     /translation="MTHEPKSSAPYAVDYTKMFDLTGQRAVVVGAGSGIGRESAIALAA
                     GGAEVICADRNLIAAKDTASRGPGMSAYELDATSSVDVEGAVAEIGAVDTLVVTAATNV
                     RKRILDYSSEEFERVIALNLRAQFDLFRGFGRGMAERGKGSIIGFSSMRATLVEPGQSV
                     YATTKGGLVQLLRTIAAELGPQGVRANAIAPGAVDTALTVPIRSNKEWDEAYATKGALD
                     RWAHPSELAGAVVFLASPAASFITGSQLCVDGGWTAVDGRYTPPMG*"
     CDS             complement(3748..5240)
                     /protein_domains="PF00171"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420324"
                     /pseudo=False
                     /translation="MTSSVRVDRTSRVALPYPSGLPVGAGWVDTPATGDVVFPYDGSFV
                     AAAPLGDVELVEQALESAAAAKDEVAALPTHVRRAALLRAHDALAASRTEVEQLLVLES
                     GKPLVDCRVEVDRTLVTLSAAADETTHIHGETVPMDLLPSGEGLLGFWVRKPIGVVAAI
                     AGFNYPLMLAAHKVAPALAAGCPVIVKPAPQTPLATLWLVHVLREALVELGAPAEAVQL
                     VTGGVDVGRRLTTDARIGLVSFTGSAAVGHQIARDAAPTKVLLELGSNAALVVAEDADL
                     PAAASAIVKGGYYASGQACISVQRVIAVESIRDELLALVKDRLADVTVGDPRDPATRVS
                     ALIDPASTERVNSWVEEAVRHGASSFTAGTAPDRVIPPTVLLDVPTDSRAWNEEIFGPV
                     VGIRGVADVEAAFDLVNDSRYGLHVSVFTASLETAFTAVNRIEAGGVVVNEVPGFRSDV
                     MPYGGVKDSGTGREGPRFAIEDMTVPRMAIIRPHTGMDS*"
     CDS             5450..6180
                     /protein_domains="PF00392"
                     /protein_domains="PF07729"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420325"
                     /pseudo=False
                     /translation="VQSDRLYRRIVEQIEDALLRGELRPGQRLPSERELVAQFGASRST
                     IREALRVLENDGVVRSRPGDKQGPELLPFSTAALARQMTRLVRFEQITIAELISSRMIF
                     DSAAARLAAVLHTADELAEMEAAVASMNAAMPDDLDAFGQADLAFHEAVARASRNTFVQ
                     VSDAVVHDVVLSLITDDIDQAQNQVSFMARSAEFHGRILAAIRERDGITAARLSRQLLF
                     DFYANHVSAEQRVLLAALVDE*"
     CDS             complement(6098..6285)
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_8420326"
                     /pseudo=False
                     /translation="MRSSAAFLRGWTRSSDTGGNHPTDDHDLMPQLGELLLVDQSGEEH
                     PLFGTDVIGVEVEQELA*"
     CDS             complement(6395..7218)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420327"
                     /pseudo=False
                     /translation="MPIQELRATHTRPVGPMRHHAAPVADLNYAKAHQRRGPRTELPAT
                     ARVVPTLSAHLRASLVVSVETPTSGLAARLHHAGLAQGGVLRWGSDQFFASILELRPAM
                     LLLDAPAAVPETLARLVRAASLVAPVAVLRPDGSDAADALDAGACDVLDPTAPTAELTW
                     RIRADLRRCPPPARNAGYPRGTSSQRLLFHIASHARSVVCCHHLRLLFGTPDLPMTLRA
                     LRARLQRLLPAFSEQGLELIVDQQWGLATYCTRSTLWTGPGESRAPSAADRG*"
     CDS             complement(7357..7526)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MSSEYGIHTHTCGTTKVGDAPCSLSPAPAQDVPHAPLTLMLHGSG
                     IDHSRSRVYEA"
     CDS             complement(7998..8893)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420328"
                     /pseudo=False
                     /translation="MTTIWQPVEATHQDVVTPAAASALHDLLDRDGDPPGVGSPLPLLW
                     HWLAFLPQARQSDLGEDGHPRTGTFLPPADGRSRMYAGGRIAIGSAPAVGEPLTRTSRV
                     SDVARKKGRTGDLMFVTVDHELASDRAAIHERQNIVYRDARRFEAREAPELREDAHAWV
                     WGRDVRIEPTLLFRFSALTYNAHRIHYDRDYATDVEGYPALVVHGPLQAVLLADAVARF
                     FPCRAVRSFEFRALAPAFDDHDLRLRLKGSSLGEAAEDAPTGGATVEVAAFSGHVKTMT
                     AAAALEPAPAAVSFTAF*"
     CDS             complement(8992..9932)
                     /protein_domains="PF03328"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420329"
                     /pseudo=False
                     /translation="MKGISEPPAASSLPGAPKVRSRPSPAEHVSTARTVLFVPGNRRDR
                     FQRALTAGADLVVVDLEDAVPPQDKDAARRAGEVLVRNGTPVAFRINDPTTPRGLGDIT
                     ALARASGGRPVTLMVPKAENPHLLQAVHDDLPAGSALIALIESAVGVLDVRSLASVPGV
                     ARLAFGHLDLSAQLGVDPDEETVLASARFAVLTASVAAGIATPIDGVCVAVRDREKILS
                     DTRRSLRAGFTAKLCIHPDQIEPVHAALAPGPDELEWARRVVDTMSEHDVGVVAGRMVD
                     RPVYLQARAIVARASRADHEHRDALRDDEERN*"
     CDS             complement(10120..11411)
                     /protein_domains="PF02515"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420330"
                     /pseudo=False
                     /translation="MQVEAASSQRAGSAGSPGRRPATGPLSGLRVIEVSSFVAAPLGGM
                     TLSQLGAEVIRVDPLDGAADTRRWPLTKSGASLYWAGLNKGKRSLMVNMRSDAGRAIVR
                     DLVATCPAGTAVVLTNAVGRPWLSYDELSAVCPDLIHVQIEGRSDGSPAVDYTVNAEVG
                     FPMVTGPAGHGDPVNHVLPAWDIACGLYAALGVSAAARRRAATGEGDQVRVALADVALA
                     MAGNLGFLAEAQVNNVQRQRIGNYLYGGFARDFTCSDGGRLMVVALTGRHWRDLLEVTG
                     MHKPVAALEESLRADFSVEDDRFEYREVLAGLFQRWFADRPMAEVCHALTGTSLVWSPY
                     RSFGQAVQHLQSSDGANPIMSIIDQPDIGPHLAPGSPLTFASAPFDAEPAPLLGQHTRA
                     ILADDLGLSAEEIEGLHRDKAVAGPLRRSSP*"
     CDS             11774..12834
                     /protein_domains="PF04851"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420331"
                     /pseudo=False
                     /translation="VTPSSPAHTQHTARLALRTDQQEGIANTVRHLRRPHTRGHVVSAC
                     GTGKTLLALRASEELGVRHLAVAVPSLDLIAQWAAAARADLRREPMITVSSLRAASHPV
                     LAAAEADSTNEGEYLAYWLARHPRATVFFTFDSLSKIEEAQHSAVFPAPVFDLLVVDEA
                     HATAGTWTKNWTALHDNSRIPADRRLYLTATPYAWEAPRLAEPPTTGPTPKRTTATAPH
                     WDDPTLLATMDQPKIFGARLHTYSHADAIDDGVLADYQLVVPTVTDDELRTALTDPEAG
                     PTARRTTALHLAILKAMREQDLNRDVVQVLDRVETPVLVIDQRIDDGQRAREVHAGLGL
                     VADDGLEDHVLGV*"
     CDS             complement(13103..13650)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420332"
                     /pseudo=False
                     /translation="VRHRYCVTDSVLHPAPNGAGIPELLSALDSYRLARQTLLGTLGLG
                     QSNRDPLAEFAEHLVAALSGGQLAESRVQANYDLRSVDGEYVQVKYLANPLSDWPNEHT
                     VRTIPGVDWYALVVYEAFAVTGVLAFPPDLTEICATLGKRHPAQSTSLQFTRRNWWTIR
                     DNADAYRQLGMRIWVPPFL*"
     CDS             14154..15328
                     /protein_domains="PF07859"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420333"
                     /pseudo=False
                     /translation="MPMGYVATTALFAWCTFFAVVAPRRPRPLATMSFWFGLGLNEVPF
                     VGIYVLVVSTALAAQGDLESPGAKVTTAVAAVVTVGLAVSAWRGVRTDQVVGRALEQGL
                     GTGWRDRVHVPLRRHRPWARILLLPGLMRQRDVQRIPNIRYGDAGRRNLLDIYRRRDTP
                     QNAPVLIYFHGGGYTSGAKNREARPLLYRLAGQGWVCISANYRLRPQTTFPGHQIDAKK
                     VIAWVREHAPEYGADPSRLFVAGSSAGSNLAALCALTPNDPVFQPGFELADTSVTAAIC
                     LYGYYGHFFGEEPDATPSPNQPYAYLNPGAPPFLIAHGTKDALATVEGARNFVDRLRRV
                     SDSTVVYAELPGGQHSFDLFHSPRFEAVVDGVEAFAAWVLAAPERTPDSAR*"
     CDS             15554..15876
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420334"
                     /pseudo=False
                     /translation="VKEANSTVEGPDGLVYTARLPLSSATLNWLADLIRGHLKKIGSRW
                     RALPAGKIAGIVLAVLRCDQLPGDLAGGNGVHRTTVARWVREVIGLLAARAPRLERALK
                     TEW*"
     CDS             16795..17330
                     /protein_domains="PF02371"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8420335"
                     /pseudo=False
                     /translation="MAAHVVHSLAREVMALNEKIAETDKLIKGRFRRHRNAEVITSMPG
                     IGVLLGAEFVAATGGDMAAFATADRLAAFAGVSPVPRDSGKVSGNLHRPTRYSRRLQRV
                     FYTSVAWSREQTAPVHEFGQHSKLCRNRTVHDFRQHGPLPRVQQGPTVWRAAEGQDLSS
                     MSGMPADISYRLLPV*"
ORIGIN
        1 tcacagggcg ccgccgtcat cgagccgctt gaactcctcg tctccgaccc cgagcagttc
       61 gtgcagcacg tcccggttgt cctggccgac ggagcgcccc agatacctga tcacgccggg
      121 tgtctgcgac atccgtgcca cgggcgcctg cacccgcacc tcgtcgagat cctcgtcctt
      181 gaccgggacg aaggtgccgc gggccttcag gtgcgggtcc gccatcagct gttgggcgtt
      241 gtagacggga cctgccgcga caccgtggtc gtcgaactgc tgcatgaccg tctgaaggga
      301 gcgttgccgg atccagtccg cgatcaggtc gtcgacggcg tcgcggttga cgatgcgacg
      361 cagcgggtcc gcgtactcgg ggtcctcccg cagctcgggt cgtccgatcg cgtcgaagac
      421 cttcagggcc accgactggg cgctgccgga cagggcgatc cagtggccgt cgccggtctt
      481 gtaggtgttg cgcggcacgc tgatggccca cttgttgccg acgcggccgg ggatcttacc
      541 cagctggtcg taggtgagtg tggcctgttc ggcgaaacgc gccagcggtt cgagcaggct
      601 caggtcgatg agctgtccct gtccggtccg ctcgcggtgc agcagcgcgg cgctgacggc
      661 gaaggcgccg tgtaccgcgg cggtgcagtc ggcgagcatg aacccgggca gggtcggcgg
      721 gccgtcggct tcaccggtga tgtgggcgaa gccgctcatc gcctcgctga tggtgccgaa
      781 cccggccttg tcgctgtagg ggccgccggc gccgtagccg gtcacgtgga tcatgacgag
      841 accctcgttg cggctggcca ggtcctcgta gctgataccc catcgttcga gggccgaggg
      901 gcgggcgttg aggatgacga cgtcgatctc ggcggcaagc cggcggaaga gctcttggcc
      961 ggcctcgacg cgcaggttca gcgacacaca ccgcttgttg cggcccaggc tcttccacat
     1021 caggttgatg tcgcccttgt tggcgcccca ctgccggatc ggatcaccgg atcccggctg
     1081 ctcgaccttg atgacgtccg cgccgtactc acccatgtag gtggcgatca tggggccggc
     1141 gaccagtgtg gccgcgtcga gcaccttgat cccgtcgaat gctcccggcg tgtgccgggg
     1201 cgacggaggg cgctggccgg tagtgccgcc gggccggctg cgggtgggtg gctggtacgc
     1261 agagttggtt gtcatgagcg gcctctcggg gcggagatgg aaacgaacgg gacgagtccc
     1321 tttgaacggc gctttgtctc ggacgggcgg gcagcgactg ggcccgggtg tgcgtgcagc
     1381 aggtcactga gtgacggcag ccgtgccttc gccggtcttg acctgggtgc cggtgcgcat
     1441 gaccgaactc atgcgcagcg cgaggacggt tccgaggatc atcagcgcac cgatgctcac
     1501 cagtccccac ttggggtggc ccgtcctgtc ggtgagccac ccgacccagt aggggccgac
     1561 gaaccccgcg atgttgccca gcgagttcac cgcggcgata ccggccgcgg cggccgcacc
     1621 ggtcaggaac gcggtcggca gccgccagaa tccggcaaag gtggagatga cggcgacggc
     1681 gcagatgaac aggcccgcat agccgaccca cgggttcgtc gcgaacgctg tcacggtcag
     1741 ggcgaggccg cccgccgcca ggaagaacgc cgtgatccgg gccggctggt tgagccggtc
     1801 gaccatgatg ccggcggcga tgatggcgat cgctccgacg gcgtagggcg ccgccgtcag
     1861 cagagtcacc gtcaggttgt cctcgatacc cagactggac ttgatgatcg tcggcagcca
     1921 gaaactcagc ccgtagagac cgaagacgag cgtgaagtag accgccgcca ggcccagcac
     1981 ccgcgggtcc ttgagcgagg ccagctccga ctgagggtga tgcgcttcga tctccgtggc
     2041 ctccgccctg agggttgcgg tcagccactc cttctccggc cggggaagcc actcggcctt
     2101 atcgggccgg tcggtcaggt aggagaacag gaacacaccg aggaggacgg tcgggatgcc
     2161 ttcgagaatg aacagccact gccagccctc gagcccgagg ccattgactt tcagcagcag
     2221 gccgcccagc ggtgcgccca gtgcggtcga cagcggtacg gcgcagaaga acaggcccac
     2281 gacccgggca cgctggcggg ccgggaacca gaacgtgagg tagaggatca tgccggggaa
     2341 gaacccggcc tcggccgcac ccagcaggat ccggatcgcg tagaagctca tctcgttcca
     2401 cacgaacgcc tggagtacag ccaccaggcc ccacgtgacc atgatgcggg ccatccacac
     2461 gcgcgccccg accctgaaca tgatcaggtt gctcgggacc tcgaagatga agtacccgag
     2521 gaagaacagt ccggcaccga gtccgaacgc tgtggcggag atcctcagcg cgtcgttcat
     2581 cgtgagcgcc gcgaccgaga ccgaggtgcg gtcgagatag gagaagaagt agcagacgca
     2641 catgatcggc agcagccgtc gcgcgacgat gcgataggca ctcgcggcaa cttccggttc
     2701 ggccggggtt gccgggcccg gcgtcacagg acctgccggc tcggtcggct gttcggtgcg
     2761 cctgtccttc gtcatggcgg cttcccctta cgtgcgggtg tcagaagaga tcaactgctg
     2821 gggcgacagc ggctgcgggt gcggttcggt caggcgccac agagcagggc ggcgtgacgt
     2881 gcgcaggtgc tgggtgcgac tcgccaagcg gcgagaagcg ggcaggcggt ggggggtcag
     2941 cccatgggcg gggtgtagcg gccgtcgacc gcggtccaac ccccgtcgac gcagagctgg
     3001 cttccggtga tgaaggacgc tgcgggagag gccaggaaca cgaccgctcc ggcgagttcg
     3061 gaggggtggg cccaccggtc gagggcgccc ttggtggcgt atgcctcgtc ccactccttg
     3121 ttggagcgga tcggcaccgt gagggcggtg tccacggcgc cgggcgcgat ggcgttcgcg
     3181 cgcactccct gtggtccgag ttcggcggcg atcgtgcgca gcagctggac caggccgccc
     3241 ttggtggtgg cgtagacgct ctggccgggc tcgaccaggg tcgcgcgcat ggagctgaag
     3301 ccgatgatgc tgcccttgcc gcgttcggcc atgccgcggc cgaagccacg gaacagatcg
     3361 aactgggcgc ggaggttgag cgcgatcacc cgctcgaact cctcgctgga gtagtccagg
     3421 atccgcttgc gtacgttggt cgcggcggtg accaccagtg tgtcgaccgc gccgatctcg
     3481 gccacggcgc cctccacgtc gacgctggat gtggcgtcga gctcgtaggc gctcatcccc
     3541 ggcccccgcg atgcggtgtc cttggcggcg atcaggttgc ggtccgcgca gatcacctcg
     3601 gcgccgcctg ccgccagggc gatggcgctc tcgcggccga tgccgctgcc ggcgccgacg
     3661 actacggcac gctgacccgt gaggtcgaac atcttggtgt agtcgacggc gtacggcgcg
     3721 ctcgacttgg gctcgtgggt catggttcag ctgtccattc cggtgtgggg gcggatgatg
     3781 gccatccggg gcacggtcat gtcctcgatg gcgaagcggg gaccctcgcg gccggtcccg
     3841 gagtccttga cgccgccgta gggcatgacg tcggagcgga agccgggcac ctcgttgacg
     3901 accacgccgc cggcctcgat ccggttgacc gcggtgaacg ccgtctccag ggacgcggtg
     3961 aagacagaca cgtgcagccc gtaacgcgag tcgttcacca gatcgaaggc cgcttcgacg
     4021 tccgcgacgc cgcggatgcc gacgacgggg ccgaagatct cctcgttcca ggcgcgggaa
     4081 tccgtgggga cgtccaggag aacggtcgga gggatgaccc gatccggggc tgttccggca
     4141 gtgaagctgg acgcgccgtg gcggacggct tcctcgaccc agctgttcac gcgctcggtc
     4201 gaggccggat cgatcagggc cgacaccctg gtggccgggt cacgcgggtc gcccacggtg
     4261 acatcggcga gccggtcctt gaccagcgcg agcaactcgt cgcggatcga ctcgacggcg
     4321 atcacccgct gcacgctgat acatgcctgc cccgacgcgt agtaaccgcc cttgacgatg
     4381 gcgctcgcgg cggccggaag gtcggcgtcc tcagcgacca ccagcgccgc attcgagccc
     4441 agctcgagca gcaccttggt cggggccgca tcacgggcga tctggtgccc gacggcggcg
     4501 gacccggtga acgagacgag ccctatccgc gcgtcggtgg tcaggcgcct gccgacgtcc
     4561 acaccgccgg tgaccagttg aaccgcctcg gcgggcgcac cgagctccac cagtgcctcc
     4621 cgcaggacgt gcaccagcca cagcgtcgcc agcggcgtct gcggggcggg tttgacgatg
     4681 acggggcagc ccgcagccag tgccggcgca accttgtggg cggccagcat cagggggtag
     4741 ttgaacccgg cgatcgcagc gacgacgccg atcggcttgc ggacccagaa cccgagcagg
     4801 ccctcaccgc tgggcagcag gtccatgggg acggtctcgc cgtgaatgtg cgtcgtctcg
     4861 tccgctgcgg cgctgagcgt gaccagtgtg cggtccacct cgacccggca gtcgaccagc
     4921 ggcttgcccg actccaggac gagaagctgc tccacttccg ttcgggaggc cgccagggcg
     4981 tcgtgcgccc tgagcagcgc tgcgcggcgt acgtgcgtcg gcagcgcggc aacctcgtcc
     5041 ttcgccgcgg ccgcggattc cagcgcttgc tccaccaact ccacgtcgcc caggggagct
     5101 gcagccacga aggacccgtc gtagggaaag accacgtcac cggtggcggg ggtgtccacc
     5161 cagccggcgc cgacaggcag gccgctcggg tagggcagcg ccacgcggga cgttcggtcg
     5221 acgcgtaccg aagatgtcat gtgcatttcc tcatctcgcc agtggcgggc gtcagatatg
     5281 gcccactgag tagacctagg tcactggtca gaccagtgcg cttcctttaa tattgaggtg
     5341 ttgcgctggc ctgtcaaggc ccatcgctag ggttgagcag cgactaggcg agtgaggggt
     5401 gcccggaatg gtgatcagcc agtgagtgga gaaaccacgt tcaagcctgt gcagtcggac
     5461 cggctctacc ggcgcatcgt cgagcagatc gaggacgctc tgctgcgcgg agagctgcgc
     5521 ccaggacagc ggctgcccag cgagcgcgaa ctcgtcgcgc agttcggagc cagtcgctcc
     5581 accattcgcg aggcgcttcg cgtactggag aacgacggcg tcgtccgctc acgcccgggt
     5641 gacaaacaag ggccagagct gctgccgttc tcgactgccg ccctggcgcg ccagatgaca
     5701 cggctcgtgc ggttcgagca gatcacgatc gccgagctga tcagctcaag gatgatcttc
     5761 gactcggccg cagctcgact ggccgcggta ctccacacgg cggacgagct cgcggagatg
     5821 gaagcagccg tcgcatcgat gaacgccgcc atgcccgacg acttggacgc attcggccag
     5881 gcggacctcg ctttccacga agccgtcgcc agggccagcc gcaacacctt cgtgcaggtt
     5941 tcggacgccg tggtgcacga cgtcgtactg tcgctgatca ccgacgacat cgaccaggca
     6001 cagaaccagg tgtcgttcat ggcgagatcg gccgagttcc acggacgaat cctggctgcc
     6061 atccgcgagc gcgacggcat cacggcagca cggctctcac gccagctcct gttcgacttc
     6121 tacgccaatc acgtcagtgc cgaacagagg gtgctcctcg ccgctctggt cgacgagtaa
     6181 gagctcgccc agctggggca tgaggtcatg gtcgtcggtg gggtggttgc cgccggtgtc
     6241 cgaggaacgt gtccagccac gcaggaatgc ggccgaactc ctcatcgcga tcggggaggc
     6301 accggggtgt acgagggggt ggcggacgcg cacctcatga gcagttcaac ggttcgccgc
     6361 gaccctcgcg acatcctccg atgtgacgag tggtcagcca cgatctgctg cgctcggcgc
     6421 ccgagactca cccggtccgg tccacagcgt gctgcgagtg cagtaggtcg ccagccccca
     6481 ctgctggtcg acaatcagct ccagtccctg ttcgctgaag gcgggcagga gccgttgcaa
     6541 tcgtgccctc agggcgcgca gggtcatggg caagtcgggg gtaccgaaca acagtctcag
     6601 gtggtggcag cagacgacgc tgcgggcatg ggaggctatg tggaacagaa gcctctggct
     6661 tgacgttcct cttgggtatc cggcatttcg ggctggtggt ggacatcgtc tgaggtcggc
     6721 ccggatgcgc cacgtgagtt cggccgtcgg cgctgtcggg tcgaggacgt cgcacgcccc
     6781 ggcatccaag gcgtcagcgg catcgcttcc gtcgggtcgc aggaccgcca cgggggcgac
     6841 gagtgatgcg gcccgtacca ggcgggccag ggtctccggg actgcggcag gcgcatccag
     6901 caacagcatc gccggtcgta gttccaggat cgatgcgaag aactgatcgc ttccccaccg
     6961 gaggacgccg ccttgggcga ggccggcgtg gtgcagacgc gccgccaggc cggaggtcgg
     7021 cgtctcgacc gacaccacca gcgacgcgcg aagatgggcc gacagcgtgg ggacgacgcg
     7081 cgccgtcgcg ggaagttccg tccgtggtcc tcggcgttgg tgggctttgg cgtagttgag
     7141 gtccgcgacc ggagccgcat gatgtctcat ggggccgaca gggcgagtgt gggtggcccg
     7201 caactcctgg atgggcatcg cgtgccctgg gaggtgaagt caacggccgt ggcgacactg
     7261 tcggtcggca agtcgtcccg tcaggcactg tggacaaacg gcggccggag acaccgacca
     7321 gcccgcgccg ttgtccgcgg atgccaccgt cgagctcaag cctcatagac acggcttctt
     7381 gagtgatcga ttccgctacc gtgcagcatg agggtcagag gggcgtgtgg aacatcttgt
     7441 gcaggcgctg gactcaggct gcacggagca tcgcccacct tggtggtccc gcaggtgtgg
     7501 gtgtggatgc cgtactccga ggacagagct gcgacgatgg ggatcccacg gccgtgttcc
     7561 tccggttgga ggtcctgggg cgaccgctgg atgcccgaag gtcccgcatc ggtgacttcg
     7621 atgcgcaggc cgcgacactc ctcggtactg atccaggaga gtcgcagtac agccggagga
     7681 agggcgtggg agacagcatt ggtgatcagt tctgatcacc aggagggcgt cctcggctgg
     7741 ttccgggaac aagttccact cggagaggat cgttcgggcg cgtcggcgca cagcggcgag
     7801 cgcctggggg acatgcggta ccaggcaggt gtgctccatg tctttgggag gcacaccgtt
     7861 cgcatgggcg gccaattcgg agactgtcgt gctcatcttg tgtccatcct cagtcaactg
     7921 agggatcatt cggtgcgtct tgggcggtga acgcctcggt cacgcctacc tgcgcgagcg
     7981 ccaaaacggc ggcacatcag aaagcagtga acgacactgc agccggggcg ggctcaaggg
     8041 cagcggcagc ggtcatggtc ttcacatggc cgctgaacgc ggcgacttcg accgtggctc
     8101 cgcctgtagg ggcgtcttcg gctgcctcgc ccaggcttga tcccttcagc ctcaaccgca
     8161 gatcgtggtc gtcgaaggcc ggcgcgaggg cacggaactc aaagctgcgc accgcacggc
     8221 agggaaagaa acgggcaacc gcgtctgcca gcagcactgc ctgcagcggg ccgtggacga
     8281 caagcgccgg gtagccttcc acatcggtgg cgtagtcgcg gtcgtagtgg attcggtgcg
     8341 cgttgtaggt cagagcggag aaccggaaca gcaaggtggg ttcgatccgg acgtcgcgcc
     8401 cccaaaccca ggcgtgtgcg tcttcccgca gctcgggagc ctcgcgggcc tcgaagcggc
     8461 gagcgtcccg gtagacgatg ttctgccgct cgtggatggc cgcacggtcg gaagcgagtt
     8521 cgtggtcgac cgtgacgaac atgaggtcac ccgttcggcc cttcttgcgg gccacatcgg
     8581 acacacgcga ggtgcgggtc agtggctctc ccaccgctgg cgcggagccg atcgcgatgc
     8641 ggcctccggc gtacatgcgg ctgcgtccgt cggcgggagg cagaaaggtg cctgttctgg
     8701 ggtggccgtc ttcacccagg tcggactgtc gcgcctgcgg cagaaaggca agccagtgcc
     8761 acagcagggg gagcggtgag ccgacgccgg gcggatcgcc gtcacggtcg agcagatcat
     8821 gcagagccga tgccgcagcg ggcgtaacga catcctggtg tgttgcctcg accggctgcc
     8881 agatagtggt catggcccgg tggtccctcc tgttggtgca aggcacttcc ctacgggtgc
     8941 ttcctgccgt gatccacctg ttggatccgg cggattgggc gctgaggcca tcagttgcgc
     9001 tcctcgtcgt ctcgaagcgc atcccgatgc tcatggtcgg cgcggctcgc tcgcgcaacg
     9061 atggcacgtg cctgcagata gacagggcgg tccaccatgc gcccggctac gacgccgacg
     9121 tcgtgctcgc tcatggtgtc gaccacgcgt cgcgcccact cgagttcatc ggggccaggt
     9181 gccagggcgg catggacggg ctcgatttgg tcgggatgga tgcacagttt ggcggtgaat
     9241 ccggcccgca gggatcggcg tgtgtcactg aggatctttt cccgatcgcg caccgcgacg
     9301 cagacaccgt cgatgggggt ggcgatcccg gcggcgaccg aggcggtgag aacggcgaat
     9361 cgggccgagg ccagcacagt ctcttcgtcg gggtccacac cgagttgggc actcagatca
     9421 agatgtccga acgcgagtcg tgcaacgccg ggaacggatg ccagggaccg tacgtcaagg
     9481 acgccgacgg cgctttcgat caaggcaatg agggccgatc ccgccgggag gtcgtcgtga
     9541 acggcctgca gcaggtgagg gttctcagcc ttggggacca tcagcgtgac aggccgaccg
     9601 ccgctcgccc gggccagcgc tgtgatgtcg cccaagcccc ggggcgtggt ggggtcattg
     9661 atacggaagg caaccggtgt gccgttgcgt accaagacct cgccggccct gcgcgcggcg
     9721 tccttgtcct gcggagggac ggcgtcctcg aggtccacga cgacgagatc ggccccggcc
     9781 gtgagggctc gttggaaccg gtcgcgacga ttgccgggca cgaagaggac cgtacgggca
     9841 gtcgagacgt gttcggccgg gctgggcctg gaccggacct tcggggcgcc cgggaggctg
     9901 gaggcggccg gtggctcgct gattcccttc atgttcaagg cggttgttcc ttcgacgtgt
     9961 gtgagttggt aggccattcg gagtggggga tccgagctga ccgtggcttg tgatgtccag
    10021 cgtcagaggc tgtgacggcc gcctccttga cgggacggat acgccgggcc tggcgtgcca
    10081 tcacgccggc acgctgccac cagcgggagg tggaaagttc atggggaact tctccgcaga
    10141 gggcccgcga cggccttgtc cctgtgcagc ccctcgatct cctcggccga caagccaagg
    10201 tcgtcggcga ggatcgcgcg agtgtgctgg ccaaggagcg gtgctggttc ggcatcgaag
    10261 ggggcgctgg cgaaggtcag cggtgatccg ggggcaaggt gtggcccgat gtccggctgg
    10321 tcgatgatcg acatgatcgg gttggcgccg tcggacgact gcagatgttg aaccgcctgt
    10381 ccgaagctgc ggtacggcga ccacaccagc gatgtcccgg tcagcgcatg acacacctcg
    10441 gccatcggcc ggtcggcgaa ccagcgctgg aacaggccgg ccagcacttc gcggtactcg
    10501 aacctgtcgt cctcgacgga gaagtcggca cgtagggatt cctcaagggc ggccacaggc
    10561 ttgtgcatgc ccgtcacctc aagcaggtca cgccagtgcc gaccggtcag ggccaccacc
    10621 atgaggcgcc cgccatcgct gcaggtgaag tcccgggcga acccgccgta caggtagttg
    10681 cctatgcgct ggcgctgcac gttgttcacc tgggcctcgg ccaggaatcc cagattgccc
    10741 gccatggcaa gtgccacatc ggccagagcg acccgcacct ggtcaccctc gcctgtagcg
    10801 gcgcgacgac gcgcggccgc ggagactccg agtgcggcgt acagcccgca ggcgatgtcc
    10861 cacgcgggca gcacgtgatt gaccggatcg ccgtgaccgg ccgggcccgt gaccatggga
    10921 aaccccacct cggcgttcac cgtgtagtcc acggccggag acccgtcgct gcgtccttcg
    10981 atctgcacgt ggatgaggtc ggggcagacg gccgagagct cgtcgtagga cagccagggt
    11041 cggcccacag cgttggtgag caccacagcg gtgcccgcag ggcaggtggc caccaggtcc
    11101 cgcacgatgg cgcgtccggc gtctgagcgc atgttgacca tcagggaccg cttgcccttg
    11161 ttcagtccgg cccagtacag actcgcgccg gacttggtga gcggccagcg tcgcgtgtcg
    11221 gcggcgccgt ccagagggtc gacgcggatc acctctgcac cgagctgcga aagcgtcatg
    11281 ccgcccagcg gggcagctac gaacgacgac acctcgatca cacgcagccc gctgagcggt
    11341 cctgtggccg gacggcggcc tgggctgcct gccgagcctg cgcgctggct cgatgctgct
    11401 tctacctgca tgaagttcca ccactctgtg ccgctgaagc ctgcacggct tggttctctt
    11461 agtgcactgg tcagaccaca gtactcgccc ctctcagggc acaccagtac tggctcgaca
    11521 ggcccgcgcg aattgagtga gagctcacac agatgagccc ggtggcacct cgtcgttacc
    11581 cacccgagct ccggcgccgc gtcctcggtg tcattggatc cagtcggaaa gtcgccgatg
    11641 tggccaagct ccttggagtc agcgcgcaga ccatgatcac gtccgtcgag gtggtgcatc
    11701 ggcggctact ccgtgggtgg agtggtccag aatggctgcc taccttgcct gcgccgtacg
    11761 tcgaggaccc gcgtgacgcc ctccagcccc gcacacaccc agcacaccgc tcgcctggcc
    11821 ctgcgcaccg accagcagga gggcatcgcc aacacggtcc gccacctgcg ccgcccgcac
    11881 acccgaggcc acgtcgtctc cgcctgcggc accggcaaaa ccctcctcgc gctgcgcgcc
    11941 tccgaggaac tgggagtgcg ccatctggcg gtggcagtgc cgagcctgga cctgatcgcc
    12001 caatgggcgg ccgccgcccg cgccgacctc cgccgcgagc cgatgatcac cgtctcgtcg
    12061 ctgcgcgccg cctctcatcc ggtgctggcc gcagccgagg ccgattccac caacgagggg
    12121 gagtacctgg cctactggct ggcccgtcac ccccgagcaa cggtgttctt caccttcgac
    12181 tccctgtcca aaatcgagga agcccagcac tccgccgtct tccccgcccc cgtcttcgac
    12241 ctcctggtcg tcgacgaggc ccacgccacc gccggcacct ggaccaagaa ctggaccgcg
    12301 ctgcacgaca acagccgtat cccggccgac cgccgcctct acctcaccgc caccccctac
    12361 gcctgggaag caccgcgcct ggccgaaccg cccaccaccg gcccgacccc caaacgcacg
    12421 accgcaacgg ccccgcactg ggacgacccc acgctgctgg ccaccatgga ccagccgaaa
    12481 atcttcggcg cccgcctgca cacctactcc cacgccgacg ccatcgacga cggcgtcctg
    12541 gccgactacc aactcgtcgt acccaccgtc accgacgacg aactgcgcac cgcgctcacc
    12601 gatccggaag ccggacccac cgcacgccgc accaccgccc tgcacctcgc catcctcaag
    12661 gccatgcgag agcaggacct gaaccgggac gtagtccagg tccttgatcg tgtcgaaacg
    12721 ccggtcctgg tcatcgatca gcgcattgat gatgggcagc gagcacgtga ggtccatgct
    12781 ggccttggtc tcgttgcgga cgatggtctc gaggatcatg tacttggcgt ctgagccagc
    12841 ctgtttggcg gcaccgttga aggtgatgct gttggccccc cggaccttca tgatcgtgac
    12901 aacggtgccc cgattgcgcg cctcctcccc gagcttgaac tcggcttcgc tgggcgcctc
    12961 agtgtcggcg ttgccgccgg tcgctcctcc tctcggatcg tcgagataga tcggcggctt
    13021 tgaggtacgc gcgttccgcc aaagccagga gtcggcgact gtccgccgag cgggaacgga
    13081 tgggtggagg acctgcgccg gctacaggaa gggaggaacc cagatgcgca tgccgagctg
    13141 ccggtaggcg tctgcgttgt cccggatcgt ccaccagttc cggcgggtga attgcaggga
    13201 ggtcgactgg gcggggtggc gcttgcccag ggttgcgcag atctcggtca ggtcaggcgg
    13261 gaaagccagg acacccgtca cggcgaacgc ttcgtagacg acaagcgcgt accagtcgac
    13321 gccggggatg gttcgcacgg tgtgctcgtt cggccagtcg gagagaggat tggcgaggta
    13381 cttgacctgt acgtactcgc cgtcgaccga tctcaggtcg tagttcgcct ggacccggga
    13441 ttcagcgagc tggcctcccg acagggctgc gaccagatgc tcggcgaact cggccagtgg
    13501 gtcccggttc gactggccga gtcccaaggt ccccagcagg gtttgccgcg ccaaccggta
    13561 ggagtccaag gcgctcaaca gctcgggtat gccagcgccg ttcggcgcgg gatgaagaac
    13621 gctatcggtc acgcagtaac gatgtcgcac caggctgcag gtccgccagt ggttctactg
    13681 tggaggtgat ggcgatatct gtaactgatt gcacgaatcc ccatcaacgg ccggacaaga
    13741 tcaatttcac cggtgatcgc tgtgccgacg ccaggagcta cgggcggatc cagaccttct
    13801 ggccgcacgg ttcgaagcgg atacccttcg gcccagtgag tggtgtgcat cgtgaagttg
    13861 caggtcatgg gtctggtgtg cgcggggtgc atggtgctcg tgctggtcgt gggcggatgg
    13921 cttcggtgaa gatcgtcggt cgccgggaga cttcgcggtt cgtcagggcc agctgggccc
    13981 tcaccagagc agtcgcccac ttcgggtcgg tgcggacctt gccgagaacg cgtgtgtgcg
    14041 ctgatgttga accgggttcg ttggatttcc caaacgagtg acctacggcg gcgcggttgg
    14101 gcggggaagt cccagcaaat ttccccgagt tgacggtggt acgttcatat acatgccgat
    14161 gggatacgtg gcgacgaccg cgctcttcgc ctggtgcacc ttcttcgccg ttgtcgcgcc
    14221 acgtcggccc cggcctctgg cgaccatgag cttctggttc ggcctgggcc tcaacgaggt
    14281 gccgttcgtg gggatctatg tcctggtggt ctccacggca ctggccgccc agggcgatct
    14341 ggagtcaccg ggtgccaagg tgacaactgc ggtggccgcc gtcgtcaccg tcggccttgc
    14401 tgtctccgcc tggcggggcg tgcgcacgga tcaggtggtc gggcgggctc ttgagcaggg
    14461 cctcgggacc ggctggcggg atcgtgtgca cgtaccgctg cgccgccacc ggccctgggc
    14521 ccgcatcctg ctgctgccgg gcctgatgcg gcagcgtgac gtgcagcgga tccccaacat
    14581 ccgctacggg gacgccggcc gccggaatct cctcgacatc taccgtcgcc gcgacacacc
    14641 gcagaacgcg ccggtcctga tctacttcca cggtggcggg tacaccagcg gagcgaagaa
    14701 ccgcgaggca cggcccctgc tctaccggct tgccggccag gggtgggtgt gcatcagcgc
    14761 caactaccgg ctgcggcccc agaccacttt ccccggccac cagatcgacg ccaagaaggt
    14821 catcgcctgg gtccgtgagc acgcccccga gtacggtgcc gatccgtcga ggctgttcgt
    14881 ggcgggcagc tccgccggct ccaacctggc agccctgtgc gcgctcacgc cgaacgaccc
    14941 ggtgttccag cccggattcg agttggccga cacctcggtc accgcggcga tctgcctcta
    15001 tggctactac ggccacttct tcggcgagga gcccgacgca acgccgtccc cgaaccaacc
    15061 gtatgcgtac ctcaaccccg gtgcgccacc gttcctcatc gcccacggta ccaaggacgc
    15121 gctggcgact gtcgagggcg cccggaactt cgtcgaccgg ctgcgccgtg tctcggacag
    15181 caccgtggtc tacgccgaac tgcccggcgg acagcactcg ttcgacctgt tccactcccc
    15241 gcgcttcgag gccgtcgtgg acggcgtcga agccttcgcc gcctgggtcc tggctgctcc
    15301 ggagcgcact cccgactcag cccgttaggt cctacgggac gcagacgacc cggtgcaggt
    15361 cgggacggtc ggtgggcagc tgggcctgga cgcctcggcg cgcggcaagc tggagccgct
    15421 gcgggcgaag atgaccaagc tcgccggccg aggctggcta cacacacggg gcggcgggcg
    15481 attcaccgcg cggttgtgat cgcgcggggg cagggcgtaa ctgacaggcc cctgacggca
    15541 gttgagtttg gtgtgaagga agccaacagc accgtcgagg gccctgatgg ccttgtctac
    15601 accgcccgcc tgccgctctc gagcgccacc ctgaattggc tcgccgacct gatccgcggc
    15661 catctgaaga agatcggctc caggtggcgg gccctgcccg cggggaagat cgcgggcatc
    15721 gtgctggcgg tactgcgctg tgaccagctg ccgggcgacc tggccggcgg caacggggta
    15781 caccgcacca ccgtcgcccg gtgggtgcgg gaggtcatcg gcctgctggc cgcccgcgcc
    15841 ccgcgcctgg agcgggccct gaagaccgag tggtgaccga agttggatcc gggatgcgtt
    15901 cgcccagtgg ttactgtgac cgttcggcga acggttccgt tccggcgcct ccaagccctc
    15961 accttgcacc gcggcgagca gaacatcgcg tccgagcggc ggtcgacgcc ggccacccgc
    16021 cgggccccgc actccgggca ctccgcctcg cccgtgccgt cccggacggc cgccaggcgc
    16081 tggcgcaacc gccgttcccg gcgccactgc ctggaccgac acgccgacga acagaactcc
    16141 gccccgggcc gggctcccgg cctcagccgt tccccgcagc cccggcagat cctttccccg
    16201 gcccgaccgg cgtcctcgga caccaggcca gcgtaggacg ccagactact cagaaccggg
    16261 gcttagaaac acgcacatag acctggcgga cggcggggcc gccctggtca tcccggtcct
    16321 gctcaaccac ggccagcaac tcctctacat tcccggacgg gcggtcaacc ggggctccga
    16381 gggctaccgg ggtgacgtca agactgatgc caaggacgcg gcggtcatcg ccgaccaggc
    16441 ccgcatccgc cgcagcctca cgcccttgcg gcccggcgaa gagctggtgt ccgactggaa
    16501 ggttctcacc cggcaccgcc gtgacctcag cgacgaccgc acccggacca tcaaccggct
    16561 ccgcggccat ctcactgagg tcttccccgg cctggaacgc gaactcgacc tgggcaatgt
    16621 cggccccttg gtaactcctg accggctacc agaccccggc cgctatctgc cggaccggac
    16681 gacggcgtct ggccacctgg ctgcgcaacc gcaaggtccg gggcgccgac gaactcgccg
    16741 ccagggccgt ccaggccgca gaaggacagc acacatccgt ccccggtgag gacatggccg
    16801 cccacgtggt gcactccctg gcgagggagg tgatggccct caacgagaag atcgcggaga
    16861 ccgacaagct catcaagggc cggtttcgcc gacaccgcaa cgcggaggtg atcacgagca
    16921 tgcccggcat cggcgtcctg ctgggcgccg aattcgtggc cgccaccggc ggagacatgg
    16981 ccgcgttcgc caccgcggac cggctggccg cgttcgccgg cgtttccccg gtgcctcgtg
    17041 actccgggaa ggtgagcggc aacctgcacc gccccacccg ctacagtcgg cgcctccaac
    17101 gcgtcttcta cacctccgtg gcttggtcac gagaacagac agcacctgta cacgagtttg
    17161 ggcagcactc gaagctctgc agaaatcgaa cagttcatga cttcaggcag cacgggcccc
    17221 tgccgagagt gcagcagggg cccacggtgt ggagagctgc ggagggccag gacctgtcct
    17281 cgatgagcgg catgccggcc gacatcagct accgtctgct gccggtctga
//
