LOCUS       reptomyces_RBGC_253894 17254 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_253894
VERSION     Streptomyces_RBGC_253894
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_002846415.1
  ORGANISM  GCF_002846415.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1428
                     /protein_domains="PF04185"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003868"
                     /pseudo=False
                     /translation="MAELTRRRLLGSAAGAIGGATALSLLPPSVRKAVAAGPPRRGSIR
                     DIEHVVMLMQENRSFDHYFGTLSGVRGFNDPHALRLPDGRSVFYQPDAVNPDGYLLPFH
                     LDTHRSSAQAIPSTSHAWAVQHAAWNGGRMDQWLPAHRKADGGNGPYVMGYYTREDIPF
                     QFALAETFTVCDHYFCSVFGPTWPNRLYWMTGTIDPGGTLGGPVITNRAPTPYRWTTYA
                     ERLQAAGVSWKVYQQDDDYGCNMLEQFAAFRSARPGSDLYERGVRPQPEGTFEDDARAD
                     RLPAVSWIMPTSFQSEHPDYLPAAGADFVARKIEAIAANPKVWAKTAFILNYDENDGLF
                     DHVPPPTPRAGTADEFVQGLPIGGGFRVPAIVVSPWTVGGWVASEPFDHTSALRFLEEF
                     TGVEEPNISQWRRRTFGDLTSAFRFTHARPRPPRLPRNTAEQLEEAKKEVATLPKPTPP
                     GADQSFPRQERGHRPHT*"
     CDS             1586..5031
                     /protein_domains="PF13088"
                     /protein_domains="PF13385"
                     /protein_domains="PF13385"
                     /protein_domains="PF13385"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003869"
                     /pseudo=False
                     /translation="MISMSFTPYNSPAPGGARAARCGPSPAGAVAGLLALAVAAVSLLL
                     AAPVSYASGPLASSRALVGAEQVLFRSGVGGYGCYRIPALVKTKTGSLLAFAEGRKSPT
                     CADRGDIDLVMRRSTNDGRTWGPAHVVLEGSPTDGTEPFTRGNPAPVVDRETGSVFLLT
                     TSNEDTPTGLRLPWVQRSDDDGVSWSAPKALPTYTGANNGWFATGPSHGVQLTEGAHAG
                     RLVVGAHQNPDSTTRYAGVLYSDDHGATWQASSTANSYVANAVKPGEVSVTELPGGSVY
                     LAARNEIGGSSNHRTRAVSSDGGTTVPASTVIPGLITPEVQGSALTLRQTYQRTPGDTM
                     VFSAPSDASDRKLMKIRYSTDQGTTWTAASNGLISNDRASYSDLAELDTGELGLVYEGG
                     PSNSADEIRFNVTTPGALGIPGTFTGKGSPQKSPTAGRTSPDSGPDANDAYLQANAALG
                     SGRFGQGLVLDGTGDYADVPYGRTIDPGAGDVTYAMWFKYAATTASRQQALFWAYGQGS
                     TKPQVWLRTQPADDRLYAWVQGAGGGAWLTLTDPSAAVAFGDDQWHHVALIRSGAQIRL
                     TVDGTVTGTATGVSGSVTDAPQNGVEGIRIGAKPDTGVSDAFGGVIDEFRVYRSALTDA
                     ALTQVRANATELDTEAATRSMGARLPFQVIDTAVVPDRRRITIEDDVSGHCASGTLLGG
                     VPALPTGRIGSLAATVDSTHPGTETGFSPTLDVGAGDFTYSLWFRYAAGSTTPDQALVW
                     AYGTGGGSPQLWVRAQPSQDRLYAWVQTDAGTAAVALPDTTSTRSFGDGAWHLMTLTRS
                     ADKVSLGVDARTPVTVSGLTGSLTPAQGSGQQGVRVGSKLDNTSVFDGDVDEFRIYHRA
                     LTAAEVSTVAGSTAGSSGSYPADLPALWWSFENQYTGAKDVVRPAAGPATPDSTVHCGH
                     GFVRGGAASVPGRFGNALAFDGSNDAVDLPYGAATALGSADFTVSTWLKYSATAGSADQ
                     VLVWAYGTGASERQIWLRAQPAQDRLYAAFETDTATTVVAAVDGSAAAGFGDGAWHHVA
                     LQRADGQLRLIVDGQTLGSAAAPAGSVTTGDTYAVDGFRLGAKPDGTNPLTGALDEFRI
                     TRKALSADELTTLRTDNSLPGTATSTWLPFQVITGSEFARM*"
     CDS             5125..6251
                     /protein_domains="PF00144"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003870"
                     /pseudo=False
                     /translation="MTDGRLRDAAQTRVEEILAEVTASGEETGVQVAAYLDGELVVDAW
                     AGLADVETGRPMEPETLVPAWSTGKGIAAALVAVLVERGMVGYDTPIAAHWPEFAARGK
                     AEITLGQVLSHSAGLPQLRPEVTPEELFDVASVGDWLAGQAPLWEPGTASGYHGWTYGV
                     LLAETLRRATGRTCDELLREELAGPLGVADALLFSVPDDLLDRVAICYDGGWSAYLDRM
                     PPHSPFFTFAPRRVLPVASLANRADFRRAALPANGTMTARAAARMYATLACGELDGVRL
                     VSEATLKEATAPRTSGEDRSLGFPLLKGYGFMLGGAGSVVRSPDGGFGTNGSGGSAASA
                     DPAHRFSFAVTKNRMSVNGLDKRLFREVREVLGIG*"
     CDS             complement(6258..7087)
                     /protein_domains="PF12697"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003871"
                     /pseudo=False
                     /translation="MPYFETSTDGTRLHYVDYGPREGRTIVFVNSSYFGTEMWEFQMLP
                     LAAEGFRCIGLDRRGHGRSDDVWDGFGLDTLAGDVGALLDHLDLTDITLVGHSVGTAEV
                     VRYLTLHGSGRVARVALVAGMAPGPARSADHPEGVDPALIEAGNEVFRKDRPGFFADGA
                     AGFFALDRPGNDVSPAHVQYWEHRCAGATARAANALGELIVTLDLAPELTKIDVPVLVI
                     HGTHDVSAPIALTGERAARLIPDSTYHVYENAGHGLFVTHADRLTADLRACAGR*"
     CDS             7234..7838
                     /protein_domains="PF08241"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003872"
                     /pseudo=False
                     /translation="VNNTVAGTQGYGADADALAGQYESVTFEEVHGGLLHLYPTSPVRA
                     LDLGAGTGRDAAALARLGHTVTAAEPTPELRLRGQRLHPEPALTWLDDALPDVPVLTER
                     GERFGLVLLTAVWMHLDPAERARGMRAVAALLAPGGILAMTIRSGPVPPGRRMFDVPEA
                     ETVALAQAAGMRVAHLGGRVDLHGRPGVRWSELVFTRP*"
     CDS             complement(7864..9053)
                     /protein_domains="PF01757"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003873"
                     /pseudo=False
                     /translation="MTHGVSRVPREVPRRGGLPTPGLSRLPSLTGLRFPAAFLVFVSHI
                     GLPVPQVRLFEDDELVADLNKATEKAGSLGVAFFFVLSGFVLTWSARPTDTARAFWRRR
                     FTKIYPNYVITWGLALLLFASAYTPARVALANLFMVHVWIPDFQYLLSVDASNWSLGCE
                     FFFYASFPLLHRLFLRIDPARLKYWIGALMAAIILTPLFTYTVLPDAGAVELATSGSAD
                     ASVKQYWFAYFLPPVRILDFALGMLVAHAVLNGRWRNIGIAWSSVLLAGSYWLAQESDM
                     LYAQRATSIVPIALLIAAAATADVKGEFTLFRNRAMVWLGEISFAFYLLHFIVLAYGRK
                     VLGHDLYSTPVASGLVVLLLAVSVLTSWALYALVERPITRRWGSSRRGGKAAAVVI*"
     CDS             complement(9153..9865)
                     /protein_domains="PF00106"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003874"
                     /pseudo=False
                     /translation="MPKTIALVTGANKGIGFEIARQLQEHGVTVLLAARDEERGKAAAA
                     KLGVPFVRLDVTDPDSIKKAATWVDLAYGRLDVLVNNAGISVPNDENLPSATSIDTMRT
                     IYETNVFGVVAVTNAFLPLLRKSPAGRIVNQSSEMGSLAYALDQNHPIWPVNNLAYNSS
                     KTALNMVTVSYAKELWGTPIKVNAVAPGWCRTDITGGEGFKSAEQGAAIAVKLATLDAD
                     GPTGTFTEDQGTVAW*"
     CDS             complement(10024..10193)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MVPMTSQGIAGVAGCPLAPGKRDVFGPEGKDPSRWTDDHALWKLE
                     AEFHGGVRLAS"
     CDS             complement(10421..11178)
                     /protein_domains="PF14021"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003875"
                     /pseudo=False
                     /translation="MVKRFSRLRVLIGATASGAALAATVLFGAAPAQAAEPGGGAAASA
                     SAASRPAAPAACSGTYQGDERLGPQYLPKPWQDPVGPLVLGYHRTGHLSPTAFLATYWD
                     STAGGWKYPPNDGFANRPDGSLDKRAVRLRVGEDLDRFGSEYGAFLAPAGADYARRALP
                     PQSLITREAAYPCAYHSYEVTKSFTVWEGRIAPWFEQRGGGEQVKLDPAFVDPGAGQKL
                     NVKWLLDHGYLKAERNVEAARSALAGVATG*"
     CDS             11532..12883
                     /protein_domains="PF01547"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003876"
                     /pseudo=False
                     /translation="MPAGQDRTSKPHPAPGLPRRRVLRTGAGVVAGAAALPVLDACAAT
                     TSDGVGADGRVNIEMWHGQNEIGAKAIEKLAADFNRSQSRIRVNASGGGVVADAMLQKV
                     TAALAAGAFPDIAYIFGSDLASIARSPKVVDLTGVMHEGDPPWNDFWPSVREAVTLHGK
                     VRAAPSLLDSLAVACNTELFQRAGIPLPRPGWTWPEFVATAKKLTDAGHGVFGTAWPGA
                     GDEDTVWRLWPMVWDLGGDVIAPDGKSIGFADAGKRALETVAQLVADKSVYIDPKPGSE
                     QMYQVFTSGRMGMVITGPWQLPNIVESKLPYDVVPMPTYSGKPLTISGPDTWTVFDNGK
                     ARSRAAVEFVRWLITPAQDVRWDIGGGSLPLSRRTEAESAWQRHSADTVGLPVFTKALE
                     TARVRPIHPAYPQISQATGEAVVSVLLGRASPAKAVRRCADKADAALLIPR*"
     CDS             12896..13899
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003877"
                     /pseudo=False
                     /translation="VDRGSRTGAPRPLTLSPADREPAERRRARRRRARGEQATAWAFIA
                     PSVLVILGLSVVPVIWSLLLSFRADDLVTPGRWVGLDNYRALSKDPGFREAVENTLTYA
                     GLYVPLSLAGGLALALALNRRIRFVGVYRTLVFIPFVVSAAAQGVLFSFIFDPQFGAAN
                     SILHKLGVSPQGFLTDPGQSLYVLLAISLWSGIGFCVVVFLAALQDVPTELVESARLDG
                     ANRAQVLRYVTLPTLAPVTAFLVLWQLITALQVFDLVYVTTKGGPLESTTVIVYFVWEQ
                     AFRTFTAGYGAAAAYVLAVALLLAGTAVTLYRRHRERTTGAASGLPRMEGVAR*"
     CDS             13897..14783
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003878"
                     /pseudo=False
                     /translation="MTASTMVTEGAAPAEAPVPRTARGRRLPFSAWHLLLAPLSLCFAL
                     PLIWLVLSSFMTNAEINRFPPALWPKGIDFGGYRYVLGNAMFPRWFANSCIVSTVAVGS
                     NLVLGALGGYAFARMRFRGSRALLALMLATMVIPFQLTMIPTFLVMKWLGLIDTLGALI
                     VPSLVTPFAVFLFRQFFLALPREMEEAAWIDGCSRLRVLFSIVAPLARPALATVAVLTF
                     LATWNDLSWPLIAINHDTQYTLQLGLTTFQGQHHTQWAAVMAGNVITVLPVLLAFLFAQ
                     RTFIQSLTSSGLKG*"
     CDS             14896..15884
                     /protein_domains="PF00294"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003879"
                     /pseudo=False
                     /translation="MPSPPAPSSRPFDLLVVGDANPDVVLGPVPRDLAYGQREQLVERA
                     DLVLGGSAAIMACGAARLGLRVAFAGRVGDDPAGAFVRTALAARGVDTSALTTDPERAT
                     PLTAVLTRGADRAILTAPGCLTATGPGDVPEELLARTRHVHAASFFLMPRLAGALAGVF
                     ARARGLGATTSLDTNDDPSGRWDPELLDPVLTVTDQVLPNAAEARALTGVAKGVAEAAA
                     ALARRGPLVVVKNGAEGALAHDGTRVTTAPALPVEPLDTVGAGDSFDAGFVAAVLRGLG
                     LADALAVAAACGSLSTRGRGGTAAQPTWDEAVARVPSLSHTAVTGVSA*"
     CDS             15882..17254
                     /protein_domains="PF11975"
                     /protein_domains="PF02056"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3003880"
                     /pseudo=False
                     /translation="MTEPTTTDTSTRTTGVTEMAEPAEVKIAFMGAGSVVFTQGLLADL
                     FAFPEFTRLRIALHDIDPERLATSEAAARHIARSLNVAPVITAHPDRRGALEGAHFVIN
                     TVQVGMNAATRTDFAVPARYGLRQTIGDTLGVGGIFRALRTFPVLRGIAEDMAELCPDA
                     WLLNYTNPMAMNLLYLHRIAPRLKAVGLCHSVYWTMHDLSELVGVDFSEVSYLAAGMNH
                     QAWVLRFERDGRDLHPLLDAAIEKDRELLRRVRVDMYRRLGHYPTETSEHSSEYVPWYL
                     HHDSEVERLRLPIGAYLDIIEDNTVSYERTRNALAAGRPLPVEGTMEYAPQIVHSIVTG
                     TPRAIYGNVPNTGLISNLPADCVVEVPCLVDASGVQPTHVGPLPPQCAALNRTYASVTD
                     LVVRAATEGEPRHVRHAAMTDAATAATLPVERIWDLCDDLVQAHGELLQPELRVLLGH*
                     "
ORIGIN
        1 atggccgagt tgacgcgacg cagactcctc ggatcggcgg cgggcgcgat cggcggcgcg
       61 acggcgctct ccctgcttcc ccccagcgtg cggaaggcgg tcgccgccgg gccgccgcgc
      121 cggggctcga ttcgcgacat cgaacacgtc gtcatgctga tgcaggagaa ccgttcgttc
      181 gaccactact tcggcacgct ctccggggtc cgcggcttca acgaccccca cgcgctgcgg
      241 ctgcccgacg gccgttcggt gttctaccag ccggacgcgg tcaaccccga cggctatctg
      301 ctgccgttcc acctggacac ccaccgctcc agcgcgcagg ccatcccgtc caccagccac
      361 gcctgggccg tgcagcacgc ggcctggaac ggcgggagga tggatcagtg gctgcccgcg
      421 caccgcaagg cggacggggg caacgggccc tatgtgatgg ggtactacac ccgcgaggac
      481 atcccgttcc agttcgccct cgcggagacc ttcacggtct gcgaccacta cttctgttcg
      541 gtcttcgggc cgacctggcc gaaccggctg tactggatga ccggcacgat cgacccgggc
      601 ggcaccctgg gcggcccggt gatcaccaac agggcgccga cgccgtaccg gtggacgacg
      661 tacgccgagc ggctccaggc ggccggggtg agctggaagg tctaccagca ggacgacgac
      721 tacggctgca acatgctgga gcagttcgcc gccttccgct ccgcgcgacc cggttcggac
      781 ctgtacgagc gcggggtgcg cccgcagccc gagggcacct tcgaggacga cgcccgggcc
      841 gaccggctgc cggcggtctc gtggatcatg ccgacgagct tccagtccga gcatccggac
      901 tatctgcccg cggcgggcgc ggacttcgtg gcccgcaaga tcgaggcgat cgcggccaac
      961 ccgaaggtat gggcgaagac cgcgttcatc ctgaactacg acgagaacga cggactgttc
     1021 gaccatgtgc cgccgccgac gccgagggcg ggcacggccg acgagttcgt ccaggggctg
     1081 ccgatcgggg gtggcttccg ggtcccggcg atcgtcgtgt cgccctggac ggtgggcggc
     1141 tgggtggcga gcgagccgtt cgaccacacg tcggcgctgc ggttcctgga ggagttcacc
     1201 ggggtcgagg agcccaacat cagccagtgg cggcgccgta cgttcggcga cctgacctcg
     1261 gcgttccgct tcacccacgc ccggccgcgc ccgccgcgcc tgccgcgcaa cacggcggag
     1321 cagctggagg aggcgaagaa ggaagtggcg acgctgccga agccgacgcc gcccggtgcc
     1381 gaccagtcct tcccgcgcca ggagaggggc caccggccgc acacgtaggc tcatacgggc
     1441 agcagtcgtc ttgagcatgg ccgttcggga ccggtcgctt ccggttcccg ggcggctctt
     1501 gtccgggagt gaacagacct tcacacggcg ttcaacagct ggtcaccagg tgttggtcga
     1561 atccggtacc tgacgatcat caccatgatc tccatgtcgt tcaccccgta caactcaccg
     1621 gcaccaggcg gcgctcgcgc cgcacggtgc ggaccgtcgc ccgccggggc cgtcgcaggg
     1681 ctgctcgccc tcgcggtcgc ggccgtctcc ctccttctcg ccgctcccgt gtcgtacgcg
     1741 agcggcccgc tggcgtcctc gcgcgccctc gtcggcgccg agcaggtgct gttccgctcc
     1801 ggtgtgggcg gttacggctg ctaccgcatc ccggccctgg tgaagacgaa gacgggcagc
     1861 ctgctcgcgt tcgcggaggg gcgcaagtcg ccgacctgcg ccgatcgcgg cgacatcgat
     1921 ctggtgatgc gccgctccac caacgacggc cgcacctggg gcccggccca tgtcgtcctg
     1981 gagggcagcc ccaccgacgg caccgagccc ttcacccggg gcaatccggc gcccgtggtg
     2041 gaccgcgaga ccggttcggt gttcctgttg accacctcca acgaggacac gcccaccggc
     2101 ctgcggctgc cctgggtgca gcggagcgac gacgacgggg tgagctggag cgcgcccaag
     2161 gcgctgccca cgtacaccgg cgccaacaac ggctggttcg ccaccggtcc ctcgcacggc
     2221 gtccagctga ccgagggcgc gcacgccgga cgcctggtgg tgggcgccca ccagaacccc
     2281 gactccacga cgcgttacgc gggcgtcctc tacagcgacg accacggtgc cacctggcag
     2341 gcgagctcca ccgcgaactc gtacgtggcg aacgcggtca agccgggcga ggtctcggtg
     2401 accgaactgc ccggcggcag cgtgtacctg gccgcccgca acgagatcgg cggcagctcc
     2461 aaccaccgca cccgcgcggt gagctccgac ggcggcacca cggtccccgc ctccacggtg
     2521 atccccggtc tgatcacccc ggaggtccag ggctcggcgc tcaccctgcg ccagacgtat
     2581 cagcgcacgc ccggcgacac catggtcttc tcggcgccgt cggacgcgtc cgaccgcaag
     2641 ctgatgaaga tccgttactc caccgaccag ggcaccacct ggacggccgc ctccaacggt
     2701 ctgatcagca acgaccgggc ctcctactcc gacctcgccg agctcgacac gggtgagctc
     2761 ggtctggtct acgagggcgg cccgagcaac tccgccgacg agatccgctt caacgtgacc
     2821 acgccgggcg cgctggggat accgggcaca ttcacgggca agggctcccc gcagaagagc
     2881 ccgacggcgg gccgcaccag cccggactcc ggcccggacg ccaacgacgc ctacctccag
     2941 gccaatgcgg ccctcggcag cggccgcttc gggcagggcc tggtcctgga cggcacgggc
     3001 gactacgccg atgtgccgta cggcaggacg atcgacccgg gtgcgggcga cgtcacgtat
     3061 gcgatgtggt tcaagtacgc ggcgacgacg gcgagcaggc agcaggcgct gttctgggcg
     3121 tacgggcagg gcagcaccaa gccgcaggtg tggctgcgca cccagcccgc cgacgaccgg
     3181 ctgtacgcct gggtgcaggg cgcgggcggc ggcgcctggc tgacgctgac cgacccgtcg
     3241 gcggcggtgg cgttcggcga cgaccagtgg caccacgtgg cgctgatccg ctcgggtgcg
     3301 cagatccgcc tcaccgtcga cggcacggtg accgggacgg cgacgggcgt gtccggttcg
     3361 gtgacggacg cgccgcagaa cggcgtggag ggcatccgga tcggcgccaa gccggacacg
     3421 ggggtgagcg acgcgttcgg cggtgtgatc gacgagttcc gcgtctaccg ctcggcgttg
     3481 acggacgcgg cgctcactca ggtgcgcgcc aacgcgacgg agctggacac ggaggccgcc
     3541 acccgttcga tgggcgcgcg gctgcccttc caagtgatcg acacggcggt cgtcccggac
     3601 cggcgccgca tcaccatcga ggacgacgtc tcgggccact gcgccagcgg gaccctgctc
     3661 ggcggtgtgc ctgccctgcc gacgggccgg atcgggtcgc tggcggcgac cgtcgacagc
     3721 acccacccgg gcacggagac cggcttctcg ccgacgctgg acgtcggcgc gggcgacttc
     3781 acgtacagcc tctggttccg gtacgcggcg ggctcgacca cgccggacca ggcgctggtg
     3841 tgggcgtacg gaacgggcgg cggcagtccg cagctgtggg tgcgcgccca gccgtcgcag
     3901 gaccgcctct acgcctgggt gcagacggac gcgggcacgg cggcggtcgc gctgccggac
     3961 accacgtcga ccaggtcgtt cggcgacggc gcctggcatc tgatgacgct gacccggtcg
     4021 gccgacaagg tctcgctggg cgtggacgcc cgtacgccgg tgacggtgag cggcctgacc
     4081 ggctcgctga cgcccgcgca gggcagcggg cagcaggggg tgcgggtcgg ctcgaagctc
     4141 gacaacacga gtgtgttcga cggtgacgtg gacgagttcc ggatctacca ccgggcgctg
     4201 acggcggccg aggtctcgac ggtggcgggg tccacggcgg gctcttccgg ttcctacccg
     4261 gccgatcttc cggcgctgtg gtggtcgttc gagaaccagt acacgggcgc gaaggacgtg
     4321 gtgcgtccgg cggcgggtcc ggcgacaccg gactccacgg tccactgcgg ccacggcttc
     4381 gtgcgcggcg gcgcggcgag cgtgccgggc aggttcggca acgcgctcgc cttcgacggc
     4441 tcgaacgacg ccgtcgacct gccgtacggc gcggccaccg cgctcggctc ggcggacttc
     4501 accgtcagca catggctcaa gtactcggcc accgccggca gtgcggacca ggtcctggtg
     4561 tgggcgtacg ggacgggcgc ctcggagcgg cagatctggc tgcgggccca gcccgcgcag
     4621 gaccggctgt acgccgcgtt cgagacggac acggcgacca ccgtggtggc ggctgtggac
     4681 ggctcggcgg cggccggttt cggcgacggg gcctggcacc acgtggccct gcaacgggcg
     4741 gatggccagc tccgcctgat cgtcgacggg cagacgctgg gcagcgcggc ggccccggcg
     4801 ggctcggtga cgacgggtga cacctacgcc gttgacggct tccggctcgg cgccaagcct
     4861 gacgggacaa atccgctgac gggcgcgctg gacgagttcc ggatcacccg caaggcgctg
     4921 tcggcggacg agctgacgac actgcgcacg gacaacagcc ttccggggac ggccacttcg
     4981 acgtggctgc cgttccaggt gatcacggga tcggagttcg cccgtatgta gctatagggc
     5041 caggtagcct gcggatacga ctgtggtggc cgtccgtcgc acttcgcggc gggcggccac
     5101 cggcgcgagg ggagagcggc tcgatgaccg atggacgact gcgggacgcc gcgcagaccc
     5161 gggtcgagga gatcctggcc gaggtgaccg cgtccggcga ggagaccggc gtccaggtgg
     5221 cggcctacct cgacggcgaa ctcgtggtgg acgcctgggc gggcctggcc gatgtggaga
     5281 ccgggcggcc gatggagccg gagacgctgg tgccggcatg gtcgacgggg aagggaatcg
     5341 cggcggccct ggtggcggtg ctggtggagc gggggatggt gggctacgac accccgatcg
     5401 ccgcgcactg gccggagttc gcggcccggg gcaaggcgga gatcaccctc ggccaggtcc
     5461 tatcgcactc ggcgggcctg ccgcagctgc gccccgaggt gactccggag gagttgttcg
     5521 acgtggcgtc ggtcggggac tggctggccg ggcaggcccc gctgtgggag ccgggcacgg
     5581 cgagcggcta ccacggctgg acatacggcg tgctcctcgc ggagaccctg cgccgggcca
     5641 ccggccgcac ctgcgatgag ctgctgcggg aggagttggc ggggccgctg ggggtggcgg
     5701 acgcgctgtt gttctcggtc ccggacgatc tgctcgaccg ggtggcgatc tgctacgacg
     5761 gcggctggtc ggcgtacttg gaccgaatgc cgccgcactc cccgttcttc accttcgccc
     5821 cgcgtcgggt gcttccggtg gcctcgctcg cgaaccgggc cgacttccgc cgggcggcgc
     5881 tcccggccaa cgggacgatg acggcccggg cggcggcccg gatgtacgcg acgctggcct
     5941 gcggcgagct ggacggcgta cgcctggtgt cggaggccac cctgaaggag gcgacggccc
     6001 cgaggacaag cggcgaggac cgctcgctgg gcttcccgct gctgaagggc tacggcttca
     6061 tgctcggcgg cgcgggttcg gtggtgcgct cccccgacgg cggcttcggc accaacggct
     6121 cgggcggcag cgcggcctcg gccgacccgg cccaccggtt ctccttcgcg gtgacgaaga
     6181 accggatgag cgtgaacggg ttggacaagc ggttgttccg ggaggtgcgg gaggtgctgg
     6241 gcatcgggtg accgggtcag cggcccgcgc atgcccgcag gtcggcggtg agccggtccg
     6301 cgtgggtgac gaacaggccg tggccggcgt tctcgtacac gtggtacgtg ctgtccggga
     6361 tgaggcgggc ggcccgctcc ccggtgaggg cgatcggggc ggacacgtcg tgggttccgt
     6421 ggatgacaag aaccgggacg tcgatcttgg tgagctcggg agcgaggtcg agggtcacga
     6481 tcagctcgcc gagggcgttg gcggcgcggg cggtggcccc ggcgcagcgg tgctcccagt
     6541 actggacgtg ggcgggcgag acgtcgttgc cgggccggtc cagggcgaag aatccggcgg
     6601 cgccgtcggc gaagaaaccc ggccgatcct tgcggaagac ctcgttcccg gcctcgatga
     6661 gggccgggtc gacgccctcg gggtggtccg ccgagcgggc cgggccgggc gccattccgg
     6721 ccaccagggc gacgcgtgcc acccgtccgc tgccgtgcag ggtgaggtag cggacgactt
     6781 cggcggtgcc gacggagtgg ccgaccaggg tgatgtcggt gaggtcgagg tggtccagga
     6841 gcgcgccgac gtccccggcc agggtgtcga ggccgaaccc gtcccacacg tcgtcggacc
     6901 gcccgtgccc gcgccggtcg agccctatgc agcggaagcc ctcggcggcc agcggaagca
     6961 tctggaactc ccacatctcc gtaccgaagt aggagctgtt gacgaagacg atggtccggc
     7021 cctcgcgcgg cccgtagtcg acgtagtgca ggcgggtgcc atcggtgctg gtctcgaagt
     7081 acggcatggc gctgggatcc tccccgtcgg cgaccgcccg ggtcggcggt gcgtcgtgtg
     7141 gtcaatggtg cggggggcgg ggcgggttgg tcgattacct cgctggtcat gcaccgccgc
     7201 tgacaccggg gttgatcgtt tagcctgacg gtgtgaacaa caccgtggcg gggacgcagg
     7261 ggtacggcgc ggacgcggac gcgctggccg gccagtacga gagcgtgacc ttcgaggagg
     7321 tccacggcgg cctgctccac ctctacccga cctcgcccgt acgggccctg gacctcggcg
     7381 ccgggaccgg ccgcgacgcg gcggccctgg cccgcctcgg ccatacggtc acggcggccg
     7441 aaccgacccc cgaactgcgc ctccgggggc agcggttgca cccggagccc gccctgacct
     7501 ggctggacga cgctctgccg gatgtgccgg tactgaccga gcgcggcgag cggttcggtc
     7561 tcgtcctgct cacggcggtg tggatgcacc tggaccccgc agagcgcgcc cggggcatgc
     7621 gagccgtcgc cgccctgctc gcgcccggcg gcatcctggc gatgaccata cgcagcggcc
     7681 cggtgccgcc ggggcggcgc atgttcgacg taccggaggc ggagacggtg gcgttggcac
     7741 aggcggcggg gatgcgggtc gcgcacctgg gcggccgcgt ggatctgcac ggccgcccag
     7801 gggtccggtg gtcggagctg gtgttcacac ggccatagcc gggccgggcg gcggacacgc
     7861 cgtcagatca ccaccgcagc agccttcccg ccccgccgcg acgaccccca ccgccgggtg
     7921 atcggccgct ccaccagcgc gtacaacgcc caggacgtca acacactcac cgccagcagc
     7981 aggaccacca gcccactggc caccggcgtc gagtaaaggt cgtgaccgag gaccttgcgg
     8041 ccgtacgcca gcacgatgaa gtgcagtagg tagaacgcga acgagatctc gcccagccag
     8101 accatcgcgc ggttccggaa cagtgtgaac tcgcccttca cgtccgccgt cgcggccgcc
     8161 gcgatcagca gggcgatcgg gacgatcgac gtggcgcgct gggcgtagag catgtccgac
     8221 tcctgggcga gccagtagct gcccgccagg agcacgctcg accaggcgat accgatgttg
     8281 cgccagcgcc cgttcagtac cgcgtgcgcc acgagcatgc cgagcgcgaa gtcgaggatg
     8341 cgtaccggcg gcaggaagta cgcgaaccag tactgcttca cggaggcgtc cgccgaaccc
     8401 gacgtggcca gttcgacggc gcccgcgtcg ggcagcacgg tgtaggtgaa cagcggcgtg
     8461 aggatgatcg ccgccatcag cgcgccgatc cagtacttga gccgcgcggg atcgatgcgc
     8521 aggaacagcc ggtgcagcag cgggaacgag gcgtagaaga agaactcgca gccgagtgac
     8581 cagttggacg cgtccacgct gaggaggtac tggaagtccg gtatccagac gtgcaccatg
     8641 aagaggttcg cgagtgccac ccgggccggt gtgtaggcgg aggcgaacag cagcagcgcc
     8701 aggccccacg tgatcacgta gttcgggtag atcttggtga accggcggcg ccagaacgcc
     8761 cgggccgtgt ccgtcgggcg ggccgaccag gtgagcacga agccgcttag gacgaagaag
     8821 aacgcgacac ccagcgaacc ggccttctcc gtcgccttgt tgaggtcggc gaccagctcg
     8881 tcgtcctcga acaggcgcac ttggggaacg ggcagtccga tgtggctgac gaagaccagg
     8941 aacgcggcgg ggaaccgcag tccggtcagc gagggcagcc gggagaggcc gggggtgggc
     9001 agcccgcctc tccggggcac ttcgcggggt acccgggaca cgccgtgtgt catggagaac
     9061 cttcctgaga acggacgtga gggcaggact ctcctgggaa gggagagtcg gacggggacg
     9121 ggggtgcgga ggggggcgcg gtgcggcgcg gctaccaggc cacggtgccc tggtcctcgg
     9181 tgaacgtgcc ggtcggaccg tccgcgtcga gggtggcgag cttcacggcg atcgccgcgc
     9241 cctgctcggc ggacttgaag ccctccccgc cggtgatgtc ggtacggcac cagcccgggg
     9301 ccaccgcgtt gaccttgatc ggggtgcccc acagctcctt ggcgtaggac accgtgacca
     9361 tgttgagcgc ggtcttggac gagttgtacg cgaggttgtt cacgggccag atcgggtggt
     9421 tctggtccaa cgcgtaggcg agcgagccca tttcactgga ctggttgacg atccggcccg
     9481 ccggcgactt gcgcagcagc ggcaggaacg cgttcgtcac cgcgaccaca ccgaacacat
     9541 tggtctcgta gatggtgcgc atggtgtcga tggaggtggc gctgggcagg ttctcgtcgt
     9601 tggggacgga gatgcccgcg ttgttcacga ggacgtcgag cctgccgtag gcgaggtcga
     9661 cccaggtggc ggccttcttg atgctgtcgg ggtcggtgac gtcgagccgg acgaacggca
     9721 cacccagctt cgcggcggcc gccttgcccc gctcctcgtc ccgagcggcc aggagcacgg
     9781 tgacaccgtg ctcctgtaac tggcgcgcga tctcgaatcc gatgcctttg ttcgcaccgg
     9841 tgaccagagc gatggtcttc ggcattacat cctccgaatg gttgtcaggg atccatttcg
     9901 ggggacgaca aatcgtctgg ccgataggag tgaaagggag gcgggatgca gatatcccga
     9961 tccggaccgg ctcgcccgag aggagtcgac gcgcggtcaa cccacctttc agccagccgg
    10021 tttcacgatg ccagacgaac tcccccgtgg aattcagcct caagcttcca cagggcatga
    10081 tcatccgtcc atcgtgaggg atctttcccc tcggggccga aaacgtcccg tttaccgggc
    10141 gcgagcgggc acccagccac cccggcaatc ccctgagaag tcataggaac catgacattc
    10201 ccaccactgg aaacagggtg gaaggtttca tttcgctgga agatccaatt ccatcgccag
    10261 agccaccgcc gaatcggaga gcttcgcgcc agccaggttt gtttcatacg gaaagcagac
    10321 ggccggagat gtctcgaacc cgccgcaccg ctgtgagcgg cgtcaccccc gaagcggccg
    10381 cgccgaaccg cacggccgcc cgccccggat gcccggaact cagccggtcg ccacccccgc
    10441 cagcgcgctc ctggccgcct ccacgttcct ctccgccttc agatacccgt ggtcgagcag
    10501 ccacttcaca ttgagcttct gccccgcccc cgggtcgacg aacgccgggt ccagcttcac
    10561 ctgttcaccg ccgccacgct gttcgaacca gggcgcgatc cggccctccc agacggtgaa
    10621 gctcttggtc acctcgtacg agtggtacgc acaggggtac gccgcctcac gtgtgatcag
    10681 gctctgcggg ggcagcgccc gacgggcgta gtccgccccg gccggggcga ggaaagcgcc
    10741 gtactcggag ccgaagcggt ccaggtcctc gcccacccgc agccgtaccg cccgcttgtc
    10801 gaggctgccg tcggggcggt tggcgaagcc gtcgttgggc gggtacttcc agccgcccgc
    10861 cgtggaatcc cagtaggtgg ccaggaacgc cgtcgggctg aggtggccgg tgcggtggta
    10921 gccgaggacc agcgggccga ccgggtcctg ccagggcttc ggcagatact gcgggccgag
    10981 gcgttcgtcg ccctggtacg tgcccgaaca ggcggccggg gccgccggtc gcgacgcggc
    11041 actcgcgctc gcggccgcgc ccccgccggg ctccgccgcc tgcgccggcg cggcaccgaa
    11101 caggaccgtc gcggccagcg ccgcgcccga ggcggtcgcg cctatgagga cccgcagcct
    11161 gctgaaacgt ttcaccatgt atgcctcctg agatgtgatg gcgtctcaca tctagtggcg
    11221 ccgcgatcgg ttgagcgtcc cgtacgcgca agtaggccga aagatcgcgc ggcgcggccg
    11281 gaagcgcact gttgtgccct gacgtggcgc gtggtgcccg gcggcacgcg aaccgcaggc
    11341 cctctcgggt acttgacgcg tgctccccga ggcgctttca tccagccagt gcggggccca
    11401 cgcggcccgg cgcttcgaga ggtgtgccca gccggtagcg gatcccgacc cgatcccgag
    11461 tccggcccga gtcgccagga cgtgtgtccc gcgtccgagg cggggcgcat ccgcgaaggg
    11521 atggacgacc atgcccgccg gtcaggaccg caccagcaag ccccaccccg cccccggcct
    11581 cccgcgccgc cgggtcctgc gcacgggggc gggcgtcgtc gccggggccg cggccctgcc
    11641 cgtgctcgac gcctgcgccg ccaccacctc cgacggcgtc ggcgccgacg gccgggtcaa
    11701 catcgagatg tggcacggcc agaacgagat cggcgccaag gcgatcgaga agctcgccgc
    11761 cgacttcaac cgctcgcagt cccgcatccg ggtgaacgcg agcggcggcg gcgtggtcgc
    11821 ggacgccatg ctccagaagg tgacggccgc gctggccgcg ggtgccttcc ccgacatcgc
    11881 gtacatcttc ggctcggacc tcgccagcat cgcccgcagc cccaaggtcg tcgatctgac
    11941 cggcgtgatg cacgagggcg acccgccgtg gaacgacttc tggccctccg tcagggaagc
    12001 cgtcaccctg cacggcaagg tccgggccgc gccctcgctg ctcgactcgc tcgccgtcgc
    12061 ctgcaacacc gaactcttcc agcgcgccgg aatcccgctg cccaggcccg gctggacctg
    12121 gcccgagttc gtggccaccg ccaagaagct caccgatgcc ggacacggtg tcttcggcac
    12181 cgcctggccc ggggcgggcg acgaggacac cgtgtggcgg ctgtggccca tggtgtggga
    12241 cctcggcggc gacgtgatcg cccccgacgg caagagcatc ggcttcgccg acgcggggaa
    12301 acgggccctg gagaccgtgg cccaactggt cgccgacaag agcgtctaca tcgaccccaa
    12361 gcccggcagc gagcagatgt accaggtgtt cacctccggc cggatgggca tggtgatcac
    12421 cggcccctgg cagctcccca acatcgtgga gtccaagctg ccgtacgacg tggtgcccat
    12481 gcccacctac agcggaaagc cgctgaccat ctccggaccc gacacctgga ccgtcttcga
    12541 caacggcaag gcgcgctccc gggcggccgt cgagttcgtg cgctggctga tcactcccgc
    12601 gcaggacgtg cggtgggaca tagggggcgg cagtctgccg ctgagcagac ggaccgaggc
    12661 cgagagcgcc tggcagcggc actccgccga caccgtcggc ctcccggtgt tcaccaaggc
    12721 cctggagacc gcccgggtgc ggcccatcca ccccgcctat ccgcagatct cccaggccac
    12781 cggcgaggcc gtggtgtccg tgcttctcgg ccgcgcctcc cccgccaagg cggtgcgccg
    12841 gtgcgccgac aaggcggacg ccgccctgct gattccccga tgaggagggc cgtcgtggac
    12901 cgaggatccc gcacgggcgc accccgcccg ctcaccctgt cccccgccga ccgggagccc
    12961 gccgaacggc gccgcgcccg gcgccggcgg gcgcgcggcg agcaggccac cgcctgggcg
    13021 ttcatcgccc cgtcggtcct ggtgatcctg gggctgagcg tggtgccggt catctggtca
    13081 ctgctgctgt cgttccgcgc cgacgacctg gtcacgcccg gccgctgggt cggcctcgac
    13141 aactaccggg ccctgtcgaa ggaccccggc ttccgcgagg ccgtcgagaa caccctcacg
    13201 tacgcgggcc tgtacgtgcc gctgagcctg gccggcgggc tcgcgctggc cctcgcgctc
    13261 aaccggcgga tccggttcgt cggcgtctac cgcaccctcg tcttcatacc gttcgtcgtc
    13321 tcggccgccg cccagggcgt gctgttctcc ttcatcttcg acccgcagtt cggcgcggcc
    13381 aactcgatcc tgcacaagct cggcgtctcg ccgcagggct tcctgaccga ccccggccag
    13441 tcgctgtacg tcctgctcgc gatctcgctg tggagcggca tcggcttctg cgtcgtcgtc
    13501 ttcctcgccg cgctccagga cgtccccacc gaactcgtcg agtccgcgcg cctggacggg
    13561 gcgaaccggg cgcaggtcct gcggtacgtg acgctgccga cgctcgcccc cgtcaccgcg
    13621 ttcctggtgc tgtggcagct catcaccgcg ctccaggtct tcgacctcgt gtacgtgacg
    13681 accaagggcg ggccgctgga gtcgaccacg gtcatcgtgt acttcgtctg ggagcaggcg
    13741 ttccgcacct tcaccgcggg ctacggcgcc gccgccgcgt acgtcctcgc cgtcgccctg
    13801 ctcctcgcgg gcacggccgt caccctctac cgccgccacc gggagcgcac caccggcgcc
    13861 gcgtccggac tgccgcgcat ggaaggagtg gcccgatgac cgcctccacc atggtcaccg
    13921 agggcgccgc accggcggag gcccccgtac cgcgcacggc acgggggcgc cgactgccgt
    13981 tcagcgcctg gcacttgctg ctcgcgccgc tgtcgctctg cttcgcgctg ccgctgatct
    14041 ggctggtgct cagctcgttc atgaccaacg ccgagatcaa ccggttcccg ccggcgctgt
    14101 ggcccaaggg gatcgacttc ggcgggtacc gctatgtgct gggcaacgcg atgttcccgc
    14161 gctggttcgc caactcgtgc atcgtctcga ccgtcgccgt cggctccaac ctggtgctcg
    14221 gcgcgctcgg cggctacgcg ttcgcccgga tgcggttccg gggttcgcgg gcactgctcg
    14281 cgctgatgct ggcgacgatg gtgatcccgt tccagctgac gatgatcccg acgttcctgg
    14341 tgatgaagtg gctggggctg atcgacacgc tcggagcact gatcgtgccg tccctggtca
    14401 ccccgttcgc ggtgttcctc ttccggcagt tcttcctcgc cctgcccagg gagatggagg
    14461 aggccgcctg gatcgacggc tgctcacggc tgcgggtgct cttctcgatc gtggcgccgc
    14521 tggccaggcc cgcgctcgcc acggtcgcgg tcctgacgtt cctcgccacc tggaacgacc
    14581 tgtcctggcc actgatcgcc atcaaccacg acacccagta caccctccag ctggggctga
    14641 ccaccttcca ggggcagcac cacacccagt gggcggcggt gatggcgggc aacgtcatca
    14701 cggtgctgcc ggtgctgctc gccttcctgt tcgcccagcg gaccttcatc cagtcgttga
    14761 cgtcgagcgg actcaagggc tgaggcggtc cggaggccga ggcgggccgg acacccgccc
    14821 ggccgacgcc aacggaagcc accgctccct gacaccccgt cacccgactc ccccggacca
    14881 gaaagccctt cgccatgccg tcaccgcccg cgccctcatc ccgccccttc gacctgctcg
    14941 tcgtcggcga cgccaacccg gacgtggtcc tcggaccggt gccgcgcgac ctcgcgtacg
    15001 gccagcgcga gcagctggtc gagcgggccg acctcgtcct cggcggctcc gccgcgatca
    15061 tggcgtgcgg cgcggcccgg ctggggctgc gcgtggcgtt cgcgggccgc gtcggcgacg
    15121 acccggcggg cgccttcgtc cgtacggccc tggccgcgcg cggagtcgac acctccgccc
    15181 tgaccaccga ccccgaacgg gccaccccgc tcaccgccgt cctcacccgg ggcgccgacc
    15241 gggcgatcct caccgcgccg ggatgcctga cagcgaccgg gcccggggac gtccccgagg
    15301 aactgctcgc ccggacccgg cacgtccacg cggcctcgtt cttcctgatg ccgcggctcg
    15361 ccggggcgct cgccggagtg ttcgcgcggg cgcgcgggct cggcgcgacc acctcgctcg
    15421 acaccaacga cgacccgtcc ggccgctggg accccgaact gctcgacccg gtcctgacgg
    15481 tgaccgacca ggtgctgccc aacgcggccg aggcgcgcgc cctgaccggg gtcgccaagg
    15541 gagtggccga ggcggcggcc gcgctggccc ggcgcggccc gctcgtcgtg gtcaagaacg
    15601 gcgccgaggg cgcactcgcg cacgacggga cgcgggtcac cacggctccc gccctgcccg
    15661 tcgagccgct cgacacggtg ggggccgggg acagcttcga cgccgggttc gtcgccgccg
    15721 tactgcgcgg cctcggcctc gccgacgccc tggccgtcgc cgccgcctgc ggctcgctgt
    15781 ccacccgcgg ccgcggcggc accgcggccc agcccacctg ggacgaggcc gtcgcccgcg
    15841 ttcccagcct cagccacacc gcggtcacgg gggtctccgc atgaccgagc cgaccaccac
    15901 cgacacgagc acccggacga ctggagtcac cgagatggcc gaaccggccg aagtgaagat
    15961 cgccttcatg ggcgcgggca gcgtcgtgtt cacccagggg ctgctggccg acctgttcgc
    16021 cttccccgag ttcacccggc tgcggatcgc gctgcacgac atcgaccccg agcggctggc
    16081 gaccagcgag gcggcggccc ggcacatcgc gaggtcgctg aacgtggcgc ccgtcatcac
    16141 cgcgcacccc gaccggcgcg gtgcgctgga gggggcgcac ttcgtcatca acaccgtcca
    16201 ggtcggcatg aacgcggcga cccgcaccga cttcgccgtc cccgcgcggt acgggctgcg
    16261 ccagaccatc ggggacacgc tcggcgtcgg cggcatcttc cgcgccctgc gcaccttccc
    16321 ggtgctgcgg ggtatcgccg aggacatggc cgagctctgc ccggacgcct ggctgctgaa
    16381 ctacaccaac ccgatggcga tgaacctcct gtatctgcac cggatcgccc cccggctcaa
    16441 agcggtgggg ctgtgccact cggtgtactg gacgatgcac gacctgtccg agctggtcgg
    16501 cgtcgacttc tccgaggtgt cgtacctggc cgccgggatg aaccaccagg cgtgggtgct
    16561 gcgcttcgaa cgggacggcc gggatctgca cccgctcctg gacgccgcca tcgagaagga
    16621 ccgcgaactg ctgcgccgcg tccgtgtgga catgtaccgc aggctcggcc actaccccac
    16681 cgagacgagc gagcactcct ccgagtacgt gccgtggtac ctgcaccacg acagcgaggt
    16741 cgagcggctg cggctgccga tcggcgcgta cctcgacatc atcgaggaca acacggtcag
    16801 ctacgagcgc acccgcaacg cgctggcggc gggccgcccg ctgccggtcg agggcaccat
    16861 ggagtacgcc ccgcagatcg tccacagcat cgtgaccggc acgccccgcg cgatctacgg
    16921 caacgtcccc aacaccggtc tgatcagcaa tctgccggcc gactgcgtgg tcgaagtccc
    16981 gtgtctggtc gacgcgtcgg gtgtgcagcc gacccacgtc ggcccgctcc cgccgcagtg
    17041 cgccgcgctg aaccgtacgt acgcgagcgt caccgatctg gtggtgcggg ccgccaccga
    17101 gggcgagccc cggcatgtgc ggcacgccgc gatgacggac gcggcgaccg ccgccaccct
    17161 gccggtggag cgcatctggg acctgtgcga cgacctcgta caggcccatg gggagctgct
    17221 ccagcccgag ttgagggtgc tgctcgggca ctga
//
