LOCUS       reptomyces_RBGC_286012 17154 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_286012
VERSION     Streptomyces_RBGC_286012
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_002551465.1
  ORGANISM  GCF_002551465.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1011
                     /protein_domains="PF00702"
                     /protein_domains="TIGR01525"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401817"
                     /pseudo=False
                     /translation="MVGTGRGAQLGILIKGPEVLETTRRADTIVLDKTGTVTTGRMTLQ
                     TTHTTHGTTTTEVLRLAGALENASEHPIAQAVATAATDTTGPLPTPEDFQNIPGLGVQG
                     IVEGHAVLVGRPRLLADAAIPLPPALSGALAEAEEHGRTAVVVAWDGEARGVFGVADAV
                     KDSSAAAVGELRALGLQPVLLTGDNRAVAEAVAREVGIDEVHAEVLPEDKVNVVKRLQA
                     EGRVVAMVGDGVNDAAALATADLGLAMGTGTDAAIEASDLTLVRGDLKVTADAIRLSRR
                     TLATIRGNLFWAFGYNVAALPLAASGLLNPMIAGAAMAFSSVFVVTNSLRLRAFT*"
     CDS             complement(1529..2826)
                     /protein_domains="PF00285"
                     /protein_domains="TIGR01798"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401818"
                     /pseudo=False
                     /translation="VSEHTNNAVVLRYGDDEYTYPVIDSTVGDKGFDIGKLRANTGLVT
                     LDSGYGNTAAYKSAITYLDGEQGILRYRGYPIEQLAERSSFLEVAYTLINGDLPKVDEL
                     ATFKNEITQHTLLHEDVKRFFDGFPRDAHPMAMLSSVVSALSTFYQDSHNPFDEQQRHL
                     STIRLLAKLPTIAAYAYKKSIGHPFVYPRNDLGYVENFLRMTFSVPAQEYELDPVVVSA
                     LDKLLILHADHEQNCSTSTVRLVGSSQANMFASISAGISALWGPLHGGANQSVLEMLEG
                     IQANGGDVDSFIRKVKNKEDGVRLMGFGHRVYKSFDPRAKIIKAAAHDVLSALGKSDEL
                     LDIALKLEEHALSDDYFVSRNLYPNVDFYTGLIYRAMGFPTEMFTVLFALGRLPGWIAQ
                     WHEMIKEPGSRIGRPRQIYTGEVLRDFVPVEGR*"
     CDS             complement(3043..5267)
                     /protein_domains="PF13604"
                     /protein_domains="PF14490"
                     /protein_domains="PF13538"
                     /protein_domains="PF18335"
                     /protein_domains="PF14520"
                     /protein_domains="TIGR01448"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401819"
                     /pseudo=False
                     /translation="MSNMAVLEGVLERITYANEENGYTVARVDTGRGAGDLLTVVGALL
                     GAQVGESLRMEGRWGSHSQYGKQFTVENYTTVLPATIQGIRRYLGSGLIKGIGPVMADR
                     ITTHFGVDTLDVIEQEPKRLVEVPGLGPKRTKMIAAAWEEQKAIKEVMVFLQGVGVSTS
                     IAVRIYKKYEDASISVVKNQPYRLAADVWGIGFLTADRIAQAVGIPHDSPERVKAGLQY
                     ALSQSSDQGHCYLPEERLIADGVKLLQVDTGLVIECLAELAADPEGVVREKVPSPEGGE
                     PVTAVYLVPFHRAELSLAGQLRRLLNTGEDRMPAFGDVDWDKALAWLATRTGADLAPEQ
                     EQAVRLALSRKVAVLTGGPGCGKSFTVRSIVELARAKKAKVVLAAPTGRAAKRLSELTG
                     AEASTVHRLLELRPGGDAAYDRDRPLDADLVVVDEASMLDLLLANKLVKAVAPGAHLLL
                     VGDVDQLPSVGAGEVLSDLLAEGGPVPAVRLTRIFRQAQQSGVVTNAHRINAGQPPLTE
                     GLSDFFLFVEDETEDAGKLAVDVAARRIPAKFGLDPRRDVQVLAPMHRGPAGAGQLNGL
                     LQQAITPARPDLPEKRFGGRVFRVGDKVTQIRNNYDKGENGVFNGTVGVVTGLDVDEQK
                     LTVRTDEDEEIGYDFDELDELAHAYAMTIHRSQGSEYPAVVIPVTTSAWMMLQRNLLYT
                     AVTRARKLVVLVGSRKAIGQAVRTVSAGRRCTALDFRLRGGSGEDFA*"
     CDS             complement(5322..5950)
                     /protein_domains="PF12802"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401820"
                     /pseudo=False
                     /translation="MADGHGANGHGADGDRDRGSGGSGNGDRDRGSDGNGNGSGSGDST
                     AGREAVRVDRVMDGLRAFGANYTEFTRRFATWLGLHSTDAAALVEILYAEDQGTPLSPA
                     RLSERVSLSSGATAILLKRLEQAGHIVRTRESTDRRVVTLRSSPGIRPRAIAFFGPYSE
                     RMAEAMAAYSPQEIQHFENFLGTLRTTMDALLAHEYEGGGPTPPTP*"
     CDS             6100..7727
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401821"
                     /pseudo=False
                     /translation="MPETAETPPTARQWLGLVAVALGVALIVVDLTIVNVILAPIIDDL
                     SIGSSEAQWIQESYAITFAALLLVTGRLSDLYGARRIFLLGLAVFGVTSLLAASAPSGG
                     PLILARFVQGVGGAMMLPTSLALLNATFTGRARGQAFAVWGSTIGAAAAVGPLLGGWLA
                     DLSWRWAFGINIPLVALIVLGVLLYLDASPRTPGRIDGVGALLSAAGLGLLAFVLIEGR
                     AYGWLMTTEPLEIGGFSWSGGLSPVFVALLLSVLALGMFWRRQTALSRAGDEPLMDVGL
                     FSVRSFRNGNFVTLMVGLGEFGIIAVLPLWLQFALGYSAFEAGLALVALAAGSFVASGA
                     SFPMAASVPALAQVRIGLVLEAAGLTVLALTASTDSSWWLIALALFVYGIGVGFATAQV
                     TNIVLVDVPERSGGQASGIQSAARELGSALGIALLTTLFFSTLASGMTDRLARDGVAAD
                     EADRLGSMVTDSAGSVIGALAAEPRTASAAEAAREAMAVGVQVSGYVCAGLLLLALAAT
                     LFMSPGPKGPSARDARRARPGAATR*"
     CDS             complement(7803..7966)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MGCDQAERRPPLSAVTKEDQPSDEKTTAGPSTALLSRTGTGTVPW
                     PRATSRHSP"
     CDS             complement(8019..8776)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401822"
                     /pseudo=False
                     /translation="VIRLARAPLPLDTAAHLTTYTEQIKQTTETDRKARAADLWAHTTV
                     RRRVRDGLLATLADMAPGHQRCMYCGDSQGTDIDHFEPKSLAPLRTFEWLNHLLACAYC
                     NSNQKRNSFPRSETDGSPLLLDPTLQEPLEHLRLVLPVGTYKGLTPRGDACIAVFGLNE
                     RGVLVDGRRTAYVTAKHAVELWRIVTDKGQHGKGTEIVRAAWNRPLADVLAAMFHQSRH
                     RNAELLFLGEEETLGLLRDRDLRAAFLSHA*"
     CDS             complement(8774..10173)
                     /protein_domains="PF13304"
                     /protein_domains="PF13476"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401823"
                     /pseudo=False
                     /translation="MYVSRVYVENIKSFHGPRVVDLTLTRPDGTHAGWTVLAGRNGSGK
                     TTLLRALALALSGPVAARGLVQGFENWMSRGAVEGQAQAKIVRDAAFDRFSASGRTTTN
                     FWAGLRWTAPAEGMSSRKSAQPALEGIRQNPKAKSATPAQRGPWADNPVGWFCAAYGPF
                     RRMAGGSGEVQRLMLASGPVARQASLFHEDASLAEGVAWLIEQHLRALEGREGAAALKQ
                     AALSVLGHGLLPDGYRVEDVDSEGLWVTRDGHRYPLREMSDGFRTVAALVVDLLKQIHD
                     AFGDDAFSGDDGEDGTGILSVPGVVIIDEIDAHLHVSWQRRIGPWLTEHFPNIQFIVTT
                     HSPYICQAADPGGLIRLPGVEEDAAPEVVSEDLYERVVYGSGDDAVLSDLFGLDTPYSE
                     QAERRRAEFVALESLVYEGDTSPETVERYKKLKELLTSSPAARVHEMSARLHRLAEGIG
                     DGEGGEAE*"
     CDS             complement(10444..11090)
                     /protein_domains="PF01510"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401824"
                     /pseudo=False
                     /translation="VNLPQPSRRHVLLAGAGGLAAVALPGTAHAVDVVEPDIDSTSQWK
                     ARTPQGPIELVGKRPTMIVVHHTVSANSSDVSRAQAHSHAHWVQDLHMDKNGWTDTGYH
                     FLVSRGGWITEGRHQSLSTLRGGRDFVMGAHTSGQNGAGIGIANEGAYHDGAQPPRAQW
                     EVLVALCAYTCGQYGIAPSRIYGHKDFGDTLCPGVLHDKLPQLRSEVAASMG*"
     CDS             complement(11263..12143)
                     /protein_domains="PF01183"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401825"
                     /pseudo=False
                     /translation="MPAYRSPSRRLKRSRGALLAGALASTAALILTGTGTAVAAPPAPD
                     EPVRAGQAWMGAGTRIEQGPASAAAGGVTPMDTSGVQGIDVSHWQGAINWGSVKAAGID
                     FAYMKATEGTTYKDSRFSANYTGSYNAGLIRGAYHFARPDVSNGATQANYFASSGGGWS
                     KDGKTLPGVLDIEHNPYGAMCYGLSTTQMRTWINDFYNTYKARTTRDAVIYTTASWWNT
                     CTGSWTGMAAKSPLWVAHWGTSSPNIPSGFPTWTIWQYSATGRVAGVSGDVDRNKFNGS
                     MARLQALANNTA*"
     CDS             12438..13144
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401826"
                     /pseudo=False
                     /translation="MTETSIPMLPCRTSLIETTVDFYTALGFATTYLQKSPYAYAVVER
                     GAVELQLYGMKEYDPASSHSGCYVLTDDVDGLHTAFRVGLKEAYGRVPARGLPRIGPLK
                     DMSYGVRQFLVTDPTGNTIRIGQPISEDRNHRPAPKETFARALHMADLFADSKQDLPGA
                     AKIIDRVLGLTDEHPAPVQKLRLLVLRGDIAQRMGDAEKAGVLLEEAAAVRLGPEEREA
                     AADTLARLAELRG*"
     CDS             complement(13196..13761)
                     /protein_domains="PF04978"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401827"
                     /pseudo=False
                     /translation="MTESATESTVETWPEPPLAGTEAAAVLGALERQRATLAWKCSGLD
                     AAGLRATVGASTVTLGGLLKHLAHVEDSHFARLWLGVPVGAPWDAVDWDSDPDWAYRSA
                     AQDTPGQLRTRWQESAARSRATVDAALRAGGGLDQLGAHVTRGGERPNLRRILLDLIEE
                     YARHVGHADLIRESVDGLTGEDPPR*"
     CDS             complement(13979..14817)
                     /protein_domains="PF01261"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401828"
                     /pseudo=False
                     /translation="MSDDHPLSRLSLNQETVKQWSLPELTEGCVKAGIGMVGLWRAPVQ
                     AYGVERTARLLADAGLTVTSLCRGGFFTALDPGTRARALDDNRAAIDEAAALSTDTLVL
                     VSGGLPPGSRDLYGARERVAEALAELAPYAAARGVRLAIEPLHPMYASDRCVVSTLGQA
                     LDLAERFPVDQVGVVVDTYHLWWDDRAPAEIARAGAGGRIHSFQLADWITPLPAGVLLG
                     RGQLGDGSVDFREFRRLVEAAGFDGPIEVEIFNEALWARDGAEALAEVAERYVRHAC*"
     CDS             complement(14815..15962)
                     /protein_domains="PF06187"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401829"
                     /pseudo=False
                     /translation="MTIHLPQGPYTPRATPLDLAPGAAAPTSRTVFSAAHVVADPYADI
                     GPDDPAAVDWESTLAFRRHLWAHGLGVAEAMDTAQRGMGLDWAGAAELIRRSAAEAKAV
                     GGRIACGVGTDQLPGDGTPTLAEVTAAYEEQLALAEENGVQPILMASRALVRAARGPED
                     YLATYAHLLRQASEPVILHWLGPMFDPALEGYWGSADLDDATDTFLKVIAEHPDKVDGI
                     KISLLDAAREIDVRRRLPGGVRCYTGDDFNYPELIAGDERGFSHALLGIFDPLGPLAAH
                     AVRVLDTGDVDGFRALLDPTVELSRHLFRSPTRFYKTGVVFLAWLSGHQDHFTMVGGLQ
                     SARSLPHLAKAYELADRLGLFPDPDLAEHRMRSLLTVHGGAR*"
     CDS             complement(16004..17154)
                     /protein_domains="PF01408"
                     /protein_domains="PF02894"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1401830"
                     /pseudo=False
                     /translation="VTRRTVRIAMNGVTGRMGYRQHLVRSILAIREQGGLDLGDGEVLW
                     PEPVLVGRRAHALEELAERHGLTEWSTDLDAVLADDTIDIYFDAQVTSARVEAIKKAIA
                     AGKHIYTEKPTATDVEGALDLARLARDAGIKHGVVQDKIFLPGLLKLKRLIDGGFFGEI
                     LSVRGEFGYWVFEGDWQEAQRPSWNYRAQDGGGIVVDMFPHWEYVLHELFGQVTSVTAH
                     VQTHVPQRWDERGKPYEATADDAAYGIFQLAGGAVAQINSSWTVRVNRDELVEFQVDGT
                     HGSAVAGLRNCRVQHRSSTPKPVWNPDLPVTESFRDQWQEVPDNQEFDNGFKAQWELFL
                     RHVALDEPYAWDLLAGARGVQLAELGLKSSAAGRRFDVPELTL*"
ORIGIN
        1 atggtcggca ccggccgcgg cgcccagctc ggcatcctca tcaagggccc cgaagtcctc
       61 gaaaccaccc gccgagccga caccatcgtc ctcgacaaga ccggcaccgt caccaccggc
      121 cgcatgaccc tccagaccac ccacaccacc cacggaacca ccacaaccga agtcctccgc
      181 ctcgccggag cactcgaaaa cgcctccgaa caccccatcg cccaagccgt cgccaccgcc
      241 gccaccgaca ccaccggccc cctccccacc cccgaggact tccagaacat ccccggactc
      301 ggcgtccagg gcatcgtcga gggccacgcc gtcctcgtcg ggcggccccg gctcctcgcc
      361 gacgcggcga tccccctccc gcccgccttg tcgggggccc tggcggaggc cgaggagcac
      421 ggccgtacgg cggtcgtcgt ggcctgggac ggggaggcgc gaggcgtgtt cggggtggcg
      481 gacgcggtca aggacagcag tgcggccgcc gtcggcgagc tgcgcgccct ggggctccag
      541 ccggtcctgc tgaccggtga caaccgggcg gtggcggagg ccgtggcgcg cgaggtaggc
      601 atcgacgagg tccacgcgga ggtgcttccc gaggacaagg tgaacgtcgt gaagcgcctt
      661 caggccgagg gccgggtcgt cgccatggtc ggcgacgggg tcaacgacgc cgccgccctc
      721 gccacggcgg atctgggact ggcgatgggc accgggacgg atgcggcgat cgaagcgagc
      781 gacctcacgc tggttcgtgg agatctcaag gtgacggctg acgcaatccg cctctccagg
      841 cgtacgctgg ccaccatcag gggcaacctc ttctgggcct tcgggtacaa cgtcgcggcc
      901 ttgcccctgg ctgcaagtgg cctgctcaac cctatgatcg cgggagccgc catggcgttt
      961 tcgtccgtgt tcgtcgtcac gaacagccta cggttgcgtg ccttcacgta acttccacaa
     1021 agagatttag atcacaccgg tttcagggta accatccggt gggttcgcga gtcttagagt
     1081 gcgagccaag gatgtcttgg gggacgtccg atggagtgtc ttgggggacg ctcctgtggc
     1141 aagcgttggc cggggcacgt gcaccgggga gctttgagcg gccctcccgt gcgtacgtac
     1201 cccggcggac cgcagcacaa cagaacaacg ggagttcagg ctccctgcag acgcccggcc
     1261 ggatcccgtg gggggaatcc gctccgggat atgggaagcg ccctgaccgt cgacccgtgg
     1321 ggggatcggc ggcggggcgc ttctcgcttt ccagccccct cccgctccag cgccctcccg
     1381 ctccagcccc cggaacgccg aatcgccccg gacaccgcgc tctgtgcgaa gcgcggtacg
     1441 cggggcgaag gcagtcggcc ggagaggccg ggcgctacgg gggggggtta cgaggtccgg
     1501 gccggcgacc tcgacacgag gtccgggtca gcggccctcg accgggacga agtcgcgcag
     1561 gacctcgccg gtgtagatct ggcgcgggcg gccgatgcgg gaacccggct ccttgatcat
     1621 ctcgtgccac tgggcgatcc agccgggaag gcggccgagc gcgaagagca cggtgaacat
     1681 ctcggtcggg aagcccatgg cccggtagat cagaccggtg tagaagtcca cgttggggta
     1741 gaggttgcgc gagacgaagt agtcgtcgga gagcgcgtgc tcctccagct tgagcgcgat
     1801 gtcgagcagc tcgtcggact tgccgagcgc ggacagcacg tcgtgggcgg cggccttgat
     1861 gatcttggcg cgcgggtcga aggacttgta cacccggtgg ccgaagccca tcaggcggac
     1921 gccgtcctcc ttgttcttca ccttgcggat gaaggagtcg acgtcgccgc cgttggcctg
     1981 gatgccttcc agcatctcca gcaccgactg gttggcgcca ccgtgcaggg ggccccacag
     2041 cgccgagatg ccggcggaga tcgaggcgaa catgttcgcc tgcgaggagc cgaccagacg
     2101 cacggtggag gtcgaacagt tctgctcgtg gtccgcgtgc aggatgagca gcttgtccag
     2161 ggccgagacg acgaccgggt ccagctcgta ctcctgggcg gggaccgaga aggtcatgcg
     2221 caggaagttc tcgacgtacc cgaggtcgtt gcgcgggtag acgaaggggt gcccgatcga
     2281 cttcttgtag gcgtacgccg cgatcgtcgg gagcttcgcc agcaggcgga tcgtcgagag
     2341 gtgacgctgc tgctcgtcga acgggttgtg gctgtcctgg tagaacgtgg acagcgcgct
     2401 gacgaccgag gacagcatgg ccatcgggtg ggcgtcgcgc gggaagccgt cgaagaaccg
     2461 cttgacgtcc tcgtgcagca gcgtgtgctg ggtgatctcg ttcttgaagg tcgccagctc
     2521 gtcgaccttc ggcaggtcgc cgttgatcag cgtgtacgcg acctcgagga acgacgagcg
     2581 ctcggcgagc tgctcgatcg ggtatccgcg gtaacgcaga atgccctgct caccgtcgag
     2641 gtacgtgatg gcggatttat aggcggcggt attgccgtat ccgctgtcca gcgtcaccag
     2701 gccggtattg gcccggagct tcccgatgtc gaagcccttg tcgccgacgg tgctgtcgat
     2761 caccgggtag gtgtactcgt catcgccgta ccgcagtact acagcgttgt tggtgtgctc
     2821 gctcacgtca tccctcaccg acgtagtgcc tcttcttcga ggtgccctga ctgtcttcca
     2881 ccctccccca ttcggctcag gagagtgcac tcggggtcgt ccattggacc tactggcggc
     2941 actgagtgcc gccaacttac tcatcctgcc cccttgactg cggttccgga agacctccgt
     3001 gacgtttccc accgatttga tcgatcattt tttcggaggg gtcacgcgaa gtcttcgccc
     3061 gagccgcccc ggagccggaa atccagtgcc gtacaacgtc tgcctgcgga aaccgtgcgg
     3121 accgcctggc cgatcgcctt acgggacccg accaggacca ccagcttcct ggccctcgtc
     3181 acggccgtgt agagcaggtt gcgctggagc atcatccagg cgctggtggt gacggggatg
     3241 acgacggccg gatactcgct gccctgggag cggtggatgg tcatggcgta cgcgtgggcc
     3301 agctcgtcca gctcgtcgaa gtcgtagccg atctcctcgt cctcgtcggt gcggacggtg
     3361 agcttctgct cgtccacgtc cagcccggtg acgacgccga ccgtgccgtt gaagacgccg
     3421 ttctcgccct tgtcgtagtt gttgcggatc tgggtgacct tgtcgccgac gcggaagacc
     3481 cggccgccga accgcttctc ggggaggtcg ggccgggccg gggtgatggc ctgctggagc
     3541 agtccgttca gctggcccgc accggccggg ccgcggtgca tcggggcgag aacctgcacg
     3601 tcacggcgtg gatcgaggcc gaacttggcc ggaatgcggc gggccgccac atcgacggcg
     3661 agcttgcccg cgtcctccgt ctcgtcctcc acgaagagga agaagtcgct cagaccttcg
     3721 gtgagcggcg gctgtccggc gttgatccgg tgggcgttcg tcacgacgcc ggactgctgg
     3781 gcctggcgga agatccgggt gaggcggacg gcggggaccg ggccgccctc cgcgagcaga
     3841 tcgctgagga cctcccccgc gccgaccgag ggcagttggt cgacgtcacc caccaggagg
     3901 aggtgggcac cgggtgccac cgccttcacg agcttgttgg cgagcagcag atcgagcatc
     3961 gacgcctcgt ccacgacgac cagatccgcg tccagcgggc ggtcccggtc gtaggccgcg
     4021 tccccgcccg gccgcagctc caggagccgg tgcacggtgg aggcctcggc cccggtcagc
     4081 tcggagaggc gtttggcggc gcgcccggtg ggggcggcca gcaccacctt ggccttcttc
     4141 gcccgggcca gctcgacgat ggaccgtacg gtgaacgact tcccgcagcc gggccccccg
     4201 gtcaggacgg ccaccttccg gctgagcgcc agccgtacgg cctgttcctg ctcgggcgcg
     4261 aggtcggccc ccgtacgggt ggcgagccag gccagggcct tgtcccagtc cacgtccccg
     4321 aaggccggca tccggtcctc gccggtgttc aggaggcggc gcagctgccc ggcgagggac
     4381 agctcggccc ggtggaaggg gaccaggtag acggccgtga ccggttcgcc gccctcgggg
     4441 gacggcacct tttcccgtac gacgccctcc gggtcggcgg cgagctcggc caggcactcg
     4501 atgaccagcc cggtgtcgac ctggagcagc ttgacgccgt ccgcgatgag ccgttcctcg
     4561 gggaggtagc agtgcccctg gtcggaggac tgggacaggg cgtactggag gccggccttg
     4621 acccgttcgg ggctgtcgtg cggaatgccg acggcctggg cgatccggtc ggcggtgagg
     4681 aagccgatgc cccagacgtc ggcggccagc cggtagggct ggttcttcac gacggagatc
     4741 gaggcgtcct cgtacttctt gtagatacgg acggcgatgg aggtggatac gccgacgccc
     4801 tggaggaaga ccatgacctc tttgatcgcc ttctgctcct cccaggcggc cgcgatcatc
     4861 ttcgtgcgtt tggggccgag gccgggaacc tcgacgaggc gcttcggctc ctgctcgatg
     4921 acgtcgaggg tgtcgacgcc gaagtgcgtg gtgatccggt cggccatcac cggcccgatg
     4981 cccttgatca gtccggagcc gagatagcgg cggatgccct ggatggtggc gggcagcacg
     5041 gtggtgtagt tctccacggt gaactgcttg ccgtactggg agtgcgagcc ccaacggccc
     5101 tccatccgca gcgattcgcc gacctgcgcg ccgagcagcg cgccgacgac ggtgaggagg
     5161 tcgccggctc cgcgtccggt gtcgacgcgg gcgaccgtgt acccgttctc ctcgttggcg
     5221 taggtgatcc gctccaggac accttcgagg accgccatgt tggacatgac ccgacgctac
     5281 cgggtggggc tgacagtgcg gttcgcggac gggactcccg tcagggggtg gggggtgtcg
     5341 gcccgccgcc ctcgtactcg tgcgccagca gggcgtccat ggtggtgcgc agcgtgccga
     5401 ggaagttctc gaagtgctgg atctcctgcg gtgagtaggc cgccatcgcc tcggccatcc
     5461 gctcggagta ggggccgaag aacgcgatgg ccctcggccg gatgccggga ctgctgcgca
     5521 gggtcaccac gcgacggtcg gtgctctcgc gggtgcggac gatgtgcccc gcctgttcga
     5581 gccgcttgag gaggatggcg gtcgcgccgg aggagagcga gacgcgttcg ctgagccggg
     5641 ccggtgacag gggtgtgccc tggtcctccg cgtagaggat ctcgacgagg gcggcggcgt
     5701 cggtggagtg cagcccgagc caggtcgcga agcggcgggt gaactcggtg tagttggccc
     5761 cgaaggcgcg cagtccgtcc atcacacggt cgacccggac ggcctcgcgg ccggccgtgc
     5821 tgtcgccgct cccgctcccg ttcccgttcc cgtcgcttcc gcggtcgcgg tctccgttac
     5881 cgcttccgcc gcttccgcgg tcgcggtctc cgtccgcccc gtgcccgttc gccccgtgcc
     5941 cgtccgccat cggcgctgcc ccactctccg ccggatccgc cgcaagccct ccggtcacgt
     6001 ctcccaccac ctgctttgac aacctacccc gccacattta cctttgccgc aaaggtatct
     6061 acctttacgg caaagcaact ttggggagtc gaagcacgat gcccgaaaca gcggaaaccc
     6121 ctcccacagc acgccagtgg ctcggcctcg tcgccgtggc gctcggcgtg gccctgatcg
     6181 tcgtcgacct gacgatcgtc aatgtgatcc tcgcgccgat catcgatgac ctctccatcg
     6241 gatcgtcgga ggcccagtgg atccaggagt cgtacgcgat cacgttcgcg gcgctcctcc
     6301 tggtcaccgg gcgcctcagc gacctgtacg gcgcacgccg gatcttcctg ctgggcctcg
     6361 ccgtcttcgg cgtgacgagc ctgctggccg cgtcggctcc cagcggcgga ccgctgatcc
     6421 tcgcccggtt cgtccagggc gtcggcggtg cgatgatgct gcccacctcg ctggccctgc
     6481 tgaacgccac gttcaccggg cgggcgcgcg gccaggcgtt cgccgtgtgg ggctcgacca
     6541 tcggagcggc ggcggccgtg ggcccgctgc tgggcgggtg gctcgccgac ctctcctggc
     6601 ggtgggcctt cggcatcaac atcccgctgg tcgccctcat cgtgctgggg gtgctcctgt
     6661 acctggacgc ctcgccccgc actccggggc gtatcgacgg cgtcggcgcg ctgctgtcgg
     6721 cggcgggcct ggggcttctc gcgttcgtcc tgatcgaggg gcgcgcgtac ggctggctga
     6781 tgacgacgga gccgctggag atcgggggat tctcctggtc cggcgggctc tctcccgtgt
     6841 tcgtcgccct gctcctgtcc gttctggccc tggggatgtt ctggcgcagg cagaccgcgc
     6901 tgagccgggc gggcgacgag ccgctgatgg acgtggggct gttctccgtc cgctcgttcc
     6961 gcaacggcaa cttcgtcacg ttgatggtcg gtctcggcga gttcggcatc atcgcggtac
     7021 tgccgctctg gctgcagttc gccctcggct acagcgcgtt cgaggcgggc ctcgccctcg
     7081 tcgcgctggc cgccggcagc ttcgtcgcct ccggggcgag cttcccgatg gccgcaagcg
     7141 tgcccgcgct cgcccaggtc cggatcggcc tggtactgga ggccgcaggg ctgacggtac
     7201 tggccctgac agcgtccacg gacagctcct ggtggctcat cgccctcgca ctgttcgtgt
     7261 acgggatcgg cgtcggcttc gccacggcgc aggtcaccaa catcgtcctc gtggacgtgc
     7321 cggagcggag cggaggccag gcctcgggca tccagagcgc ggcccgcgag ctcgggtcgg
     7381 ccctcggcat cgccctcctg accaccctgt tcttcagcac cctggcctcc ggaatgaccg
     7441 accggctcgc ccgggacgga gtcgcggccg acgaggcgga ccggctcggg agcatggtga
     7501 cggacagcgc cggatcggtg atcggggcgc tggccgcgga gccgcgtacg gcgtcggcgg
     7561 cggaggcggc ccgcgaggcg atggcggtcg gcgtccaggt ctccgggtac gtctgcgcgg
     7621 ggctgctgct cctggcgctg gccgcgacgc tgttcatgtc gccggggccg aagggccctt
     7681 cggcccggga cgcgcgacgc gcacgacctg gtgcggcgac tcggtgagta gtccggcgag
     7741 gcgctgggga cgaacgggtt cttcgagcgg tggatgaagg acctggagac gaagtaggga
     7801 atcagggcga gtgccttgag gtcgcccgcg gccacggcac cgtccccgtc cccgtccgcg
     7861 acagcaaggc cgttgacggt ccggctgtcg tcttctcatc cgacggctgg tcttccttcg
     7921 tcaccgcgct caagggcgga cgcctctccg cctgatcgca ccccacgccc ggtgaggccc
     7981 cgtcggcacc acccggccgg ggccgccgga ccggatgtca cgcgtgggac agaaacgccg
     8041 cgcgcaggtc ccggtcacgt agcagcccca gagtctcttc ctcaccgagg aacaacaact
     8101 ccgcgtttct gtggcgggat tggtggaaca tcgccgccag tacgtccgcg agcggccggt
     8161 tccaggctgc ccggacgatc tccgtcccct tgccgtgctg gcccttgtcg gtgacgatgc
     8221 gccacagctc gaccgcgtgc ttggcggtga cgtatgcggt tctgcgtccg tcgacgagaa
     8281 cgccacgctc gttgagcccg aacacggcta tgcaggcatc gccccgcggt gtcagcccct
     8341 tgtacgtacc caccggcagg accagccgca ggtgctccag cggctcttgg agcgtggggt
     8401 cgagaaggag ggggcttccg tccgtctccg agcgcgggaa gctgttccgt ttctggttgc
     8461 tgttgcagta cgcgcaggcc agtaggtggt tgagccactc gaaagtacgc agcggggcaa
     8521 ggctcttcgg ctcgaaatgg tcgatgtccg taccctggct gtcaccgcag tacatgcagc
     8581 gttgatgacc gggggccatg tccgcgaggg tggcgaggag accgtcacgg acacgacggc
     8641 ggaccgtggt gtgagcccac aggtcagcgg ctctcgcctt gcggtcggtt tcggtcgtct
     8701 gcttgatctg ttcggtgtac gtggtgaggt gcgctgccgt gtccaggggc agcggagccc
     8761 gtgccagccg gatcactccg cctcgccgcc ctctccgtcc ccgattccct ccgcgaggcg
     8821 gtggagacgg gcggacatct cgtggacccg cgcggccggg gagctggtga gtagttcctt
     8881 gagcttcttg tagcgctcga ccgtctccgg tgaggtgtcg ccctcgtaca ccagggactc
     8941 cagcgcgacg aactcggcac ggcggcgctc ggcctgttcg gagtacggcg tgtcgagccc
     9001 gaagaggtcg gagaggaccg cgtcgtcacc gctgccgtag accacacgct cgtacaggtc
     9061 ctcggacacc acctcgggtg ccgcgtcctc ttccacgccc ggcagacgga tcaggccacc
     9121 gggatcggcc gcttggcaga tgtaggggct gtgggtggtc acgatgaact ggatgttggg
     9181 gaagtgctcg gtcagccagg ggccgatgcg gcgctgccag gagacgtgga gatgtgcgtc
     9241 gatctcgtcg atgatcacga caccgggcac cgagaggatg ccggtaccgt cctcgccgtc
     9301 gtccccgctg aacgcgtcgt cgccgaaagc gtcgtgaatc tgcttgagca ggtcgacgac
     9361 gagtgcggcc accgtgcgga atccgtcact catctcccgt agcgggtatc gatggccgtc
     9421 gcgggtcacc cacaggcctt cggagtcgac gtcctccacc cggtatccgt ccgggagcag
     9481 tccgtggccc agcaccgaga gcgccgcctg tttgagtgct gcggccccct cgcggccttc
     9541 gagcgctcgt aggtgctgct cgatcagcca ggcgacgcct tcggcgagag aggcgtcctc
     9601 gtggaacagg cttgcctgtc gggccaccgg gccggaggcc agcatcagcc gctggacctc
     9661 gcctgatccc ccggccatgc gccggaaggg accgtaggca gcacagaacc agcccacggg
     9721 gttgtccgcc caggggccgc gttgagcagg tgtggcgctc ttggccttgg ggttctgcct
     9781 gatgccttcg agtgccggct gcgcgctctt gcggctgctc atgccttccg ccggggccgt
     9841 ccatcgcagg cccgcccaga agttggtcgt ggtgcgcccg gacgcgctga acctgtcgaa
     9901 ggccgcgtcc ctgacgatct tcgcctgcgc ctggccttcg actgctccgc gcgacatcca
     9961 gttctcgaac ccctggacca gcccacgcgc ggcgaccggt ccgctgaggg ccagtgccag
    10021 cgcccggagc agtgtggtct ttcccgagcc gttccgtccc gcgaggaccg tccagcctgc
    10081 gtgcgttccg tccgggcggg tcagagtcag atcgacgaca cgtgggccgt gaaacgactt
    10141 gatgttctcg acgtacacgc gggagacgta catgggtgac ggttccgtcc ggtgtgggag
    10201 gggcggggcg gggcgggctg ttccggttcc gtgccagccg ggagcctgcc gaaccggccc
    10261 acgaaattcg gtgatgcctt ggccgggtgt cgaagccact cgtccatgct gccccacccc
    10321 gtcgccttcg ccgtgcacat caccctggcg gacgagtcta ggagacgtgg ggcatgcggc
    10381 gatttcgatc agcccctcag ctgctcagcc gccccgccga tcagcccctc agccctcacc
    10441 cctcacccca tgctcgccgc gacctcgctg cgcagttgcg gcagcttgtc gtgcagcacg
    10501 cccgggcaga gggtgtcgcc gaagtccttg tgcccgtaga tgcggctcgg cgcgatgccg
    10561 tactggccgc aggtgtaggc gcagagcgcc accaggacct cccactgggc acgcggcggc
    10621 tgcgctccgt cgtggtacgc gccctcgttg gcgatgccga tgcccgcccc gttctggccg
    10681 gaggtgtgcg cgcccatgac gaagtccctg ccgccccgca gggtgctgag gctctggtgg
    10741 cgtccctcgg tgatccagcc gccccggctg acgaggaagt ggtagccggt gtcggtccag
    10801 ccgttcttgt ccatgtgcag gtcctggacc cagtgggcgt ggctgtgggc ctgggcacgg
    10861 gagacgtcgg agctgttggc gctgaccgtg tggtgtacga cgatcatggt gggccgcttc
    10921 cccaccagct cgatcggtcc ctgcggcgta cgggctttcc actgggacgt gctgtcgatg
    10981 tccggttcga cgacgtcgac ggcgtgggcc gtgccgggta aggcgactgc cgcgaggccg
    11041 ccggcgccgg cgagcaggac gtgacggcgg gacggctggg gaaggttcac ggcggactcc
    11101 tggcgtgtgg tcgttccggg cctgccggac agcgacagtg acagtgacag tgacagtgac
    11161 agtgacaacg gtgctgacag tgacaacggc gtcgactgcg gcaggtggcg gcggtacggc
    11221 cggggggctg tacccacccg gccgccgcga gtacggggcc gctaagccgt gttgttggcg
    11281 agggcctgga gccgggccat ggagccgttg aacttgttgc ggtccacgtc gccggagact
    11341 ccggcgaccc gccccgtggc cgagtactgc cagatcgtcc acgtggggaa gccgctgggg
    11401 atgttcgggc tgctggtgcc ccagtgggcc acccagagcg gggacttggc ggccatgccg
    11461 gtccagctac cggtgcaggt gttccaccaa ctggccgtcg tatagatcac ggcatcccgg
    11521 gtggtgcgcg ccttgtacgt gttgtagaag tcgttgatcc acgtgcgcat ctgggtcgtg
    11581 gagaggccgt agcacatggc gccgtacggg ttgtgctcga tgtccagcac cccggggagg
    11641 gtcttgccgt ccttggacca ccctccgccg ctgctcgcga agtagttcgc ctgcgtcgcc
    11701 ccgttggaga cgtcggggcg ggcgaagtgg taggcgcccc ggatcaggcc ggcgttgtag
    11761 gagccggtgt agttggcgct gaagcggctg tccttgtagg tcgtgccctc ggtggccttc
    11821 atgtaggcga agtcgatgcc cgcggccttc accgagcccc agttgatcgc cccctgccag
    11881 tgggagacgt cgatgccctg gacgccgctg gtgtccatcg gtgtcacgcc gcccgccgcc
    11941 gcggacgcgg gaccctgctc gatgcgggtc cccgctccca tccacgcctg tccggcccgg
    12001 accggctcat cgggtgcggg cggtgcggcg acggccgtgc ccgtgccggt caggatcagg
    12061 gcagcggtac tggcgagcgc ccctgccagc agggctcctc gggatctctt gagtcggcgg
    12121 gacggagaac ggtacgcggg catagccacc tccgggcacg ttgacgggaa gagatccatg
    12181 gcatccgatt accggacgcc atggacatgt catgagtaac gcacgggcgg ggggaaggcg
    12241 taaagaggcc ctgcggtcta gacctgttct gccgcactcc acctgcgaaa acgtgcggga
    12301 acgacgaaaa ttttcaccgc tgaaggtctc cggcacccac ccccgcccca tggatgcacg
    12361 acgacacgca agagcggcga ccggccgccg gggcacacct tgcccccagt actcaaattt
    12421 gactacgctg tcgggtatga ccgagacgag catcccgatg ctgccctgcc gcacctcgct
    12481 gatcgagacc accgtcgact tctacaccgc cctcggcttc gcgacgacgt acctgcagaa
    12541 gagcccgtac gcgtacgcgg tcgtcgagcg gggagcggtc gaactccagc tgtacggcat
    12601 gaaggagtac gacccggcgt cctcccactc cgggtgctat gtcctcaccg atgacgtgga
    12661 cggcctgcat acggcgttcc gggtcggcct caaagaggct tacgggcgcg tcccggcacg
    12721 ggggttgccg cgcatcggtc cgctgaagga catgtcgtac ggggtgcggc agttcctggt
    12781 gaccgacccg accgggaaca cgatccggat cgggcagccg atcagcgagg accggaacca
    12841 ccggcccgcg ccgaaggaga ccttcgcccg cgccctgcac atggcggacc tcttcgcgga
    12901 ctccaagcag gatctgccgg gcgcggcgaa gatcatcgac cgggtgctgg ggctgacgga
    12961 cgagcacccg gccccggtgc agaagctgcg ccttctcgtc ctgcgcgggg acatcgcgca
    13021 gcgcatgggc gacgcggaga aggccggggt gctgctggaa gaggccgcgg cggtccggct
    13081 cgggcccgag gagagggaag ccgccgccga cacgctggcc cggctcgcgg agctgcgggg
    13141 ctgatcagcc gaagggggcg tcggtggtcc acacccgccg gatccggccc cggttcacct
    13201 cggcgggtcc tcgcccgtca ggccgtcgac ggattcccgg atgaggtcgg cgtggccgac
    13261 gtggcgggcg tactcctcga tgaggtccag gaggatgcgg cggaggttcg ggcgttcgcc
    13321 gccacgggtg acgtgggcgc cgagctggtc caggccgccg cccgcgcgga gcgccgcgtc
    13381 gaccgtggcc cgggagcggg ccgccgattc ctgccagcgg gtgcgcagtt gcccgggggt
    13441 gtcctgggcg gcggagcgat aggcccagtc ggggtcgctg tcccagtcca ccgcgtccca
    13501 gggggcgccg accggaacac cgagccacag acgggcgaag tggctgtcct cgacatgtgc
    13561 caggtgcttg agcaggccgc ccagggtgac ggtggacgcg ccgacggtgg ctcgcagtcc
    13621 ggcggcgtcc aggccggagc acttccaggc gagcgtggcc cgctggcgct ccagcgcgcc
    13681 gaggacggct gccgcctcgg tcccggcgag gggaggttcg ggccaggttt ccacggtgct
    13741 ctccgttgcg ctctccgtca tggcggacac ggtagcggag ccggaacagc ggggccggaa
    13801 cagcggaatg gggcccggcc ttacggccgg acccccctcg ctttcccctc ccgtcgggcc
    13861 ttcccgttcc ccccggaccc ctccccggaa gtacccgacg ccatgtgtga cacgggaggg
    13921 tacgcaaagg ttgcagccct ttacgatctc tttgccggcg gggcggtgcg ggggctctca
    13981 gcaggcgtgt cgcacgtagc gctccgccac ttccgccagg gcctccgccc cgtcgcgggc
    14041 ccacagcgcc tcgttgaaga tctccacctc gatcgggccg tcgaagccgg cagcttccac
    14101 gagacggcgg aactcacgga agtccacgct gccgtcgccc agttggcccc ggcccagcag
    14161 gacgcccgcc ggcagcgggg tgatccagtc ggccagctgg aaggagtgga tgcggccgcc
    14221 cgcgcccgcg cgggcgatct ccgccggggc ccggtcgtcc caccagaggt ggtaggtgtc
    14281 gacgaccacc ccgacctggt cgaccgggaa gcgttccgcg aggtccaggg cctggccgag
    14341 cgtggagacg acgcagcggt cggacgcgta catcgggtgc agcggctcga tcgccaggcg
    14401 tacgccgcgc gccgccgcgt acggggccag ttcagccagc gcctcggcga cccgctcccg
    14461 ggccccgtac agatcgcggc tgccgggcgg gaggccgccg gagaccagga ccagggtgtc
    14521 ggtggacagg gccgccgcct cgtcgatcgc cgcccggttg tcgtccaggg cgcgggcgcg
    14581 tgtccccggg tcgagtgcgg tgaagaagcc gccccggcag agactggtga cggtgagccc
    14641 ggcatccgcc aggagcctgg ccgtgcgctc gacgccgtac gcctgcaccg gggcccgcca
    14701 caggcccacc atgccgatgc ccgccttgac gcagccctcg gtcagctcgg gcagcgacca
    14761 ctgcttgacg gtctcctggt tgagggagag gcgggagagg gggtggtcgt cgctcatcgt
    14821 gcgcctccgt ggaccgtgag cagggagcgc atccggtgtt ccgccaggtc cgggtccggg
    14881 aacaggccca ggcggtcggc cagttcgtac gccttcgcca gatgcgggag cgagcgtgcg
    14941 gactggagcc cgcccaccat cgtgaagtgg tcctggtggc cggagagcca ggccaggaac
    15001 accacgcccg tcttgtagaa gcgggtcggc gaccggaaga ggtggcggga gagttcgacc
    15061 gtggggtcca ggagcgcccg gaagccgtcc acgtctcccg tgtccagcac ccgtaccgcg
    15121 tgcgccgcca acggccccag cgggtcgaag atacccaaca gggcgtggct gaagccgcgt
    15181 tcgtcgcccg cgatgagttc cgggtagttg aagtcgtcgc ccgtgtagca gcgcaccccg
    15241 cccggcaggc ggcggcggac gtcgatctcg cgggccgcgt ccaggaggga gatcttgatg
    15301 ccgtcgacct tgtcggggtg ttcggcgatg accttgagga aggtgtccgt ggcgtcgtcg
    15361 aggtcggcgc tgccccagta gccctccagt gccgggtcga acatcgggcc cagccagtgc
    15421 aggatcaccg gctccgacgc ctggcgcagg agatgggcgt acgtggcgag gtagtcctcc
    15481 gggccccgcg cggcgcggac cagcgcgcgg gaggccatga ggatcggctg gacgccgttc
    15541 tcctcggcca gggccagctg ctcctcgtac gccgccgtga cctcggccag ggtgggcgtc
    15601 ccgtcgccgg gcagttggtc ggtgcccacg ccgcaggcga tcctgccgcc caccgccttc
    15661 gcctcggcgg cggagcggcg gatcagttcg gccgcgcccg cccagtccag gcccatgccg
    15721 cgctgggcgg tgtccatggc ctccgcgacg cccaggccgt gcgcccacag atggcggcgg
    15781 aaggcgagcg tggactccca gtcgacagct gccgggtcgt ccggaccgat gtccgcgtac
    15841 gggtccgcga ccacgtgcgc cgccgagaag accgtacggg aggtgggggc cgcagccccc
    15901 ggagcgaggt cgagcggtgt cgcgcggggc gtgtaggggc cctgcgggag gtggatcgtc
    15961 atgtcagcgg cccccgccgg agccgcgcac cggtcgtccg ggtcacaggg tcagctccgg
    16021 aacgtcgaag cggcggcccg cggcggacga cttcagcccc agctcggcca gttggacacc
    16081 ccgggcgccg gccagcaggt cccaggcgta cggctcgtcc agggccacat ggcgcaggaa
    16141 cagctcccac tgcgccttga agccgttgtc gaactcctgg ttgtccggca cctcctgcca
    16201 ctggtcgcgg aaggactcgg tgacggggag gtccgggttc cagaccggct tgggggtcga
    16261 cgagcggtgc tgcacgcggc agttgcgcag cccggcgacg gcggagccgt gggtgccgtc
    16321 gacctggaac tcgaccagtt cgtcgcggtt gacccgcacc gtccaggagg agttgatctg
    16381 cgcgacggcc ccgcccgcca gttggaagat gccgtacgcg gcgtcgtcgg cggtcgcctc
    16441 gtacggcttg ccccgctcgt cccagcgctg cggaacgtgc gtctgcacat gggccgttac
    16501 ggaggtgacc tgcccgaaca gctcgtggag cacgtactcc cagtgcggga acatgtcgac
    16561 gacgatgccg ccgccgtcct gcgcgcggta gttccacgac gggcgctggg cctcctgcca
    16621 gtcgccctcg aagacccagt agccaaactc cccgcgcacg gagaggatct cgccgaagaa
    16681 gccgccgtcg atcaggcgct tcagcttcag caggcccggc aggaagatct tgtcctggac
    16741 gacgccgtgc ttgatgcccg cgtcccgggc gagccgggcc aggtcgagcg ccccctcgac
    16801 gtccgtggcg gtcggcttct cggtgtagat gtgcttgccc gccgcgatcg ccttcttgat
    16861 cgcctccacc cgggcagagg tgacctgggc gtcgaagtag atgtcgatcg tgtcgtccgc
    16921 gaggaccgcg tccaggtcgg tcgaccactc ggtcaggccg tggcgctcgg cgagttcctc
    16981 cagggcgtgg gcccggcggc cgacgagcac gggctcgggc cacagcacct cgccgtcgcc
    17041 gagatccagg cccccctgct cacggatcgc gaggatcgag cgcaccaggt gctgccggta
    17101 tcccatgcgc cccgtgacgc cgttcatggc gatgcgcact gtcctgcgtg tcac
//
