LOCUS       reptomyces_RBGC_288358 16992 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_288358
VERSION     Streptomyces_RBGC_288358
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001279495.1
  ORGANISM  GCF_001279495.1
            .
FEATURES             Location/Qualifiers
     CDS             2..2202
                     /protein_domains="PF03176"
                     /protein_domains="PF03176"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247259"
                     /pseudo=False
                     /translation="VIRALTGFSTRNPWKVIALWAVLGIALTILGQALVFRATQSNTGD
                     FLPSTYDSAAALKVAEERFGVKPDANTLTVLVARPDGAPLSGADERRIDEEAAQLGRHR
                     VAMPKPEQETPFARDHSQTPKVAPVMTAPERGFRLLSVELQGNPQDPGLHDTYRAFREH
                     ARAGFAEAGFRTGYTGGLASTVDGVDAEETRSRVVGIVMLGVIVLLHVLVFRSVLAALL
                     PLIVVTVIGGAATGTVVGVAMLTGVTLDPSTPQLIGVVLVGIGIDYFLFLLFRFREQLR
                     RRPEQPGRAAAAEVSGRVGTAVTSAALTIVAAFATLGVASFGQFRVLGPAIAVSVLVML
                     FGSLTFMPALLAVTGRRMFWPSRAHRREARGGSAGRLGTWLVKRPLTAALGSVVLLGAL
                     AAGMAGMRMDYGSGGAGGERTAAAATAAEISRAMPAGVSDPISVYVTASDGAQLTTGRV
                     DALSGTLSRVEGVGQVAPTVLSEDRRAARIDLFPNADPHGQEARDLASGAVRDAVSAHR
                     PDGTEAHVGGTAAVFADVSTAVDEDLRLVFPVAAVLIALILFLLLRSLLAPLILMLAVG
                     LGFAATLGAATLVFQHGLDQPGVAFTLPLVLFLFVVALGTDYNILVTDRIREEMERPGP
                     AREAVARAVRHTAPAVATAGLVLAASFGSLAVNPVAATQQIGFATGLGILLSAFVLSIV
                     LVPACAVLLGRSLWWPARPRPAAPLPGAGAQAPERVPVP*"
     CDS             complement(2301..4093)
                     /protein_domains="PF04069"
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247260"
                     /pseudo=False
                     /translation="MPRLPLGAWVDSGVDFLQSRLSWLFDAISALVTGLYDGLVAVLSA
                     PAPLLFAGILAIAAWWLRGLFAGLLAFAGFALVDSVGLWPDAMSTLSLVLVATLVTLVF
                     AIPLGIWAARSDRVSAVLRPLLDFMQTMPAMVYLIPGIIFFGVGVVPGIIATIVFSLPP
                     GVRMTELGIRQVDAELVEAAEAFGTTPRDTLVRVQLPLALPTLMAGVNQVIMLGLSMVV
                     IAGMVGGGGLGGAVYRAIGNVDIGLGFEAGLSIVILAMYLDRMTGALGRQVSPLGRRTL
                     ARARSAATGAARVWNHRPQPAYAVTGAVVLALVAGGLSTFGGSGGEDGPEGADNIGKGR
                     TVSIGYIPWDEGIASTYLWKELLERRGFKVDTRQLEAGALYTGLAGGGLDFQTDAWLPV
                     THAQYWEKYGDKLEDLGSWYGPTSIELAVPSYMKDVRSLADLKGKSGQFKGRIIGIEPS
                     AGAMALLKDKVMKEYGLEGEYQVVDGSTPGMLAELKRAYDKKEPVVTVLWSPHWAYSSY
                     ELTKLEDPKAVWGKGDGIHTLAREGFAADEPEVAAWLRSFKLTEEQLTGLEAKIQQTGK
                     GKEQQAVRAWLQDHPDVAALS*"
     CDS             complement(4094..5154)
                     /protein_domains="PF00005"
                     /protein_domains="TIGR01186"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247261"
                     /pseudo=False
                     /translation="VSTLQAEHVYKVFGNRPDDAVRALEGGGDRSELRADGATAAVIDV
                     SFDVEPGQIFVVMGLSGSGKSTLLRMLNGLLEPTAGRILFGGQDLTALSARELRRVRST
                     KISMVFQHFALFPHRNVLENAGYGLEVQGVPRADRDRRAAEALALCGLEGWEMAWPDEL
                     SGGMQQRVGLARALATDAELLLMDESFSALDPLIRRDMQDQLLELQRTLKKTIVFITHD
                     LNEAMRLGDGIAVMRDGRVVQQGTAEDILTRPADDYVASFVQDVDRSRVLTADAVMTTT
                     RPHRPGADSCGCPTVTADTPLAELCAVSARVPHPVTVTGTDGAVVGSVPQDRLVAFIGD
                     EQRAPVRCAEVAA*"
     CDS             complement(5407..6191)
                     /protein_domains="PF00392"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247262"
                     /pseudo=False
                     /translation="MPSPSRGGGPAAMPKYQRIAAALRRDLDRAARTPGGRLPSERSLA
                     ARYQVNRQTIRAALQYLREDGLVVTGRRGSRPAVSAEVVPAAADPVAFAPASPAPALSR
                     SWVTVVTVPPSLAVLLGMSGGDRTLVHHHRERGRTGETLRHAVTYFSPDVVARSPELAA
                     CRGRAGHAGERDLASLRGWLEQAAAAGRVAETITMTRTTHPPASAPSSAPACGLTVRRT
                     VHAPSGPLLAVTDLAFPTWDHLTIHRDRRHPAAAGFRVV*"
     CDS             complement(6337..7892)
                     /protein_domains="PF04183"
                     /protein_domains="PF06276"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247263"
                     /pseudo=False
                     /translation="MEPVDLNAAADAYAAAPLLNCLLREAAEPTGPAGAGPAGAAVHRL
                     RGSGRLLRVRGGRRPVHPELRTANGWHPLSHTELVKLVSDELGRFTGVTNDELPVEIAD
                     SRDALLALLAARAGAEPPADPYVLSEQSLVTGHPHHPAPKARGGAPAGSWLPYAPEAHA
                     RFPLVFLGVREDQCVEEGGRAASEAVDSLAGLLDGPAAPAGYRLLPAHPWQLDLVEDRP
                     AVREAFADGRLLRLGASRRPAWPTASIRTLHVPGPAADLFVKFSLDVRITNDVRRLWRH
                     DLLKLRRTDAAVEAGFAALRRTGSDAAWLADRGYRTAAFAFEELAVLVRDGLRAHTVPG
                     ATPLLAAALAEGYPGSPPAGAADPAAWWRAYLRQVVPPVLELFARHGVVLEAHLQNTLV
                     AVDASGMPVQALFRDAEGVKLLPDLPRADAWQRLVYCLVVNNLSEVAGALADRYPDISP
                     LLWPAVREELLRYDSLRGLPEIAGLLAAPALPAKTNLLLRWTRADGADARYRPLPNPLR
                     E*"
     CDS             8010..9532
                     /protein_domains="PF04183"
                     /protein_domains="PF06276"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247264"
                     /pseudo=False
                     /translation="MPIPSSAAEEAVAAELATVRPALGPPYAAALGIARAAVLTRLWRA
                     LAFEPLPWVVGREATPAGLALLLAGGRRLEGPTPDPYATRPYVDELLLDGRSHNRAGRL
                     VRALGVPHGEEFAAELDASTASLALSRAGQPPAGDDHGDHAARATWEWEQRVVDGHPYH
                     PNCRSRPGFSVAEQLAYAPEHRPVVELGLVSVRAEECLVTGDWPARLRDGGRILVPVHP
                     WQAAHVLKHERVRTGFAAHPLMALRTLAPAEGGPHVKTALSARLTSSVRDISVYSIETA
                     AAVSAFAQGLAERLDGRLHITRTLGAATAHSPDLAAVLREPPEAYADAAAGERVLPVAA
                     LGCYPPARSAAWRARFARLALSVCLRVLELGVALEAHGQNLLVVLSPDGEPLRLVYRDL
                     ADIRISPARLRAHGLAVPPLSGRLVTDDVTVLRRKLFGSLLTGALGATAGSAAAFADAL
                     AVAAALPATADTGALLTERLPTKALTLMRLSPGVPGDQWAELPNPLIGG*"
     CDS             9567..10219
                     /protein_domains="PF13649"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247265"
                     /pseudo=False
                     /translation="MTASSYLHSVRASYDAVAVDCARLLGTELAGKPLDRAMLAAFAEC
                     VRAEGGGAGRAVADLGCGPGRVTAHLDGLGVRAFGVDLSPAMVAVARRTYPGLRFEVGS
                     MSALDVADGVLGGVLGWYSTLHTPPAELPAVFAEFARVLAPGGHALIAFEAGDGRVRLE
                     HAYGHPVDLDVYRMPPGRTAALLAGAGLAEVARLLREPAPGESCPQGFLLARKG*"
     CDS             10409..10539
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MEARGDLTPCEAAPCVVWPTSSSWTRATSESTVSAVDLLGPRR"
     CDS             10625..11013
                     /protein_domains="PF18029"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247266"
                     /pseudo=False
                     /translation="MACRISELVLDCAEPERLAEFWSRVLGYVELGREDDGGIEIGPPD
                     AGFGGPQPTLVLSPSDDPRTGKLRLHIDVNATDRDQPAELERLLALGARPVDIGQDGTE
                     TWHVLADPEGNEFCLLHRRLPPLAP*"
     CDS             11052..11467
                     /protein_domains="PF18616"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247267"
                     /pseudo=False
                     /translation="MGNLLLHLGRTLDELDPPRWGDPADGATRLVRKVHGLRSVPLGDL
                     RPADLLSLVTQQVALPFVLPLDVRLPADEPLLDAYFHEGDLLLATVSVPAGAWAALPEL
                     EARLRAVIAELPGAAVDELPRGGAEALAQFAGKA*"
     CDS             complement(11469..12667)
                     /protein_domains="PF00067"
                     /protein_domains="PF00067"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247268"
                     /pseudo=False
                     /translation="MSLVDLTAHADEFNADPYPFYEALRAAGPVHRLVLGGERAWLVVG
                     HEEAREALSHPALSKNWLGSELFEVAQVHAVATNMLDSDPPHHTRLRRLVAREFTSRRV
                     ESLRPRVQQITDGLLDAMDAVPERRGDLIRSFAVPLPMTLICELLGVPNLDRARFRYWS
                     GEIVAPLDGVGAHPRVLEEMTSYLCELVAAKAREPGDDLLSALIRTRDEDGDQLSPDEL
                     IGMAFLLLVAGHETTVNLIGNGVRALLDHPEQLAALRADPDGLIDGAVEEMLRYDGPVQ
                     HATYRFAGADLELGGVPIATGSSVLVALAAADRDPARFTGPGPGPEAFDIRRAGPGHLA
                     FSHGIHYCLGAPLARMEGRIAIRSLLERFPGLAGDPDAGPLDWLPGTLMRGVTRLPLRW
                     *"
     CDS             12857..14388
                     /protein_domains="PF01565"
                     /protein_domains="PF08031"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247269"
                     /pseudo=False
                     /translation="MSLHRRQVLGGAAAAVLATVGAAAGGPDYGALARGIDGRLVLPGD
                     RDYPEARRLFQPRYDAVAPAAVAYPAHAQDVAVCLDFARRAAVPVVPRGGGHSYAGWST
                     RTGALVLDAGAMAAVAVEGDGVRIGAGARLGDVHTALAGRGLSVPTGLCPSVGIAGLTL
                     GGGLGLASRAYGTTADRLTGARVVTADGTVREVSADRDPDLFWALRGGGGGNFGVVTEF
                     RFRTHPVGDCAFAELHWPDGASAGVLRGWQRWLAGLPDPFWSQVEFTVEAGTGAGPGAA
                     AAVVPSVRVVCLDGRQELERQLTRLSDLVGAAPRDSWVVVRSHGDTVRAMSGCLDLSAA
                     ECRLPGTLPGRDPRGRLGRDSYAARSDFWAGAGLPDAAIDAVLDAVRRYGADAPRGGLG
                     VVQFDGVCGGAVNRVPVGATAFAHRDAAFLAQYLVYWPESAPAADVARHEAWLDGLWRD
                     LRPWSSGRAYQNYIDPKLSGWREAYYGPNLARLEEVRRAHDPDRLFRFPQAV*"
     CDS             14402..15597
                     /protein_domains="PF13365"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247270"
                     /pseudo=False
                     /translation="MRRTLTVAAAAAALLVSAGPLPAAGAGSAAAAPAAAGRWGAHEAE
                     SWWTPERMASARPLPPVPPLPGEEPQTPADPVQIPPVEPPVPPVEPPVPPVEPPEPAPV
                     ATPSPSGTPTVAAPEPEPAGTPNILPAPEPAGTPSILPAPAPVRPALPRIPAAGPGVGQ
                     DFGGLPVVGRMFLVKGGGSYFCTASVVASPGRNLVVSAAHCLLGADTQQVAFVPQYTRA
                     KPRPFGMFPVVRTAAGRSKIWIDQRYRTQGVNRAAALDVAFAQVGPGAKGLRVQDVVGG
                     NRLVTGAGYAHARATLIGHPSTAARPRLCVNRTTKYTSTDSRIPGSFLRIACTGYPGGT
                     SGGPFLLRLDGRTGTGDVVGVIGGWKTGGDKPDVSYSSYFGTDIRKLYEKAVAGAKAS*
                     "
     CDS             complement(15552..15943)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247271"
                     /pseudo=False
                     /translation="MELPTIAAPGVGERADAAADAACHLYDTVAPWGPGAPGGWSRTAA
                     EDAAEAIETTAYALASAAPGAEVVLAPVHAALADLRRRLGLAPAELLTGDGLPAVPRTV
                     GNPRRTRWVRALTTPSPRQPPSRTTS*"
     CDS             complement(16046..16992)
                     /protein_domains="PF03547"
                     /protein_domains="PF03547"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5247272"
                     /pseudo=False
                     /translation="MGGAAALEKLVPVLLAFGGGVLLARRKVVPAEAAKVFSDYAFLFA
                     MPCYLFGNIYASDLAALFNWRAIGGYAAAAAAAVAVVAVAAVARGRREPRAVALRVMAG
                     VQVNTAYFAVPVFITVFGTAAPIFPILLFQVCVLSLVVIALMELGRAGPAEGGPGRRLS
                     RAVGASLATPLVLACNAGILLNLLSVRVPAVALEGAAFVGNSASPVALFALGLHLGGVG
                     LHLRGTTREELALIGFKCLAFPLLAWAVCGLLFGVRGDWLAYLVLIAAMPTPQNLFIFA
                     QRYDVGVDLSASVVIKTSLVSLVLLPLWLQTVAA*"
ORIGIN
        1 gtgatccgcg ccctgaccgg gttctcgacg aggaatccgt ggaaggtgat cgccctgtgg
       61 gccgtgctcg gcatcgccct gacgatcctg gggcaggcgc tcgtcttccg cgccacccag
      121 agcaacaccg gcgatttcct gccctcgacc tacgactcgg cggcggccct gaaggtcgcc
      181 gaggagcggt tcggggtgaa accggacgcc aacacgctga ccgtgctggt ggcccggccg
      241 gacggcgcgc cgctgagcgg ggccgacgaa cggcgcatcg acgaggaggc cgcgcagctg
      301 ggccgccacc gggtggccat gccgaagccc gagcaggaga cgccgttcgc ccgggaccac
      361 tcgcagactc cgaaggtcgc cccggtcatg acggcccccg agcggggctt ccggctgctg
      421 tccgtggaac tgcagggcaa cccccaggac cccggactgc acgacaccta ccgggcgttc
      481 cgcgagcacg cccgggccgg gttcgccgag gccgggttcc ggaccggcta caccggcggg
      541 ctcgcctcca ccgtcgacgg cgtcgacgcc gaggaaaccc ggtcccgggt ggtcggcatc
      601 gtgatgctcg gcgtcatcgt gctgctgcac gtgctggtct tccgcagcgt gctcgccgca
      661 ctgctgccgc tgatcgtggt gaccgtcatc ggcggcgccg cgacgggcac ggtggtcggc
      721 gtcgcgatgc tgaccggcgt caccctggac ccgtccaccc cgcagctgat cggcgtggta
      781 ctggtcggca tcggcatcga ctacttcctc ttcctgctgt tccgcttccg cgagcagctg
      841 cgccgccgcc ccgaacagcc ggggcgtgcc gccgccgccg aggtctccgg gcgggtgggt
      901 acggcggtga cctcggccgc gctgacgatc gtcgcggcgt tcgccacgct cggggtggcc
      961 tccttcgggc agttccgggt gctcggtccg gccatcgccg tgtccgtgct ggtgatgctg
     1021 ttcggcagcc tcaccttcat gccggccctg ctcgccgtca ccgggcgcag gatgttctgg
     1081 ccctcgcggg cccaccggcg cgaagcccgc ggcggctcgg ccggtcggct gggcacctgg
     1141 ctggtcaagc ggcccctgac ggcggcactg ggctccgtgg tgctgctggg cgccctcgcc
     1201 gcgggcatgg ccggcatgcg gatggactac gggtcgggtg gcgcgggcgg tgagcggacg
     1261 gccgccgcgg ccaccgcggc cgagatctcc cgggcgatgc cggcgggcgt gtcggacccg
     1321 atcagcgtct acgtcaccgc gtcggacggc gcacagctca ccaccggccg ggtcgacgcc
     1381 ctgtccggga cgctctcccg ggtggagggg gtggggcagg tcgccccgac ggtgctgagc
     1441 gaggaccgtc gggcggcgcg catcgacctg ttcccgaacg ccgatccgca cggccaggag
     1501 gcccgcgacc tggcctccgg cgcggtccgt gacgcggtgt ccgcgcaccg gccggacggc
     1561 accgaggccc atgtgggcgg taccgcggcg gtgttcgccg atgtctcgac ggccgtggac
     1621 gaggacctgc ggctggtgtt cccggtcgcg gcggtcctga tcgcgctcat cctcttcctg
     1681 ctgctgcgga gcctgctcgc cccgctgatc ctgatgctgg cggtggggct ggggttcgcc
     1741 gccacgctgg gcgccgcgac gctcgtcttc cagcacgggc tggaccagcc gggcgtggcc
     1801 ttcacgctgc cgctggtgct gttcctgttc gtggtggcgc tgggcaccga ctacaacatc
     1861 ctggtgaccg accggatccg ggaggagatg gagcggcccg gtccggcccg ggaagcggtg
     1921 gcccgggcgg tgcggcacac cgcgccggcc gtggcgacgg ccgggctggt gctggccgcc
     1981 tccttcggca gcctcgcggt caacccggtc gcggccacgc agcagatcgg cttcgcgacg
     2041 gggctcggga tcctgctctc cgccttcgtc ctgtcgatcg tcctggtccc ggcgtgcgcg
     2101 gtgctgctcg gccggtccct gtggtggccg gcacggccgc ggccggcggc gccgctgccc
     2161 ggcgccgggg cgcaggcacc ggagcgggtg ccggtgccct gagcggggcc cgtacgcgcg
     2221 caggcgccgg tgtgcgcgga ttcccgtacg gggtccgcgc acaccggcgc ctgtggaggc
     2281 ccttccggtg tgccgcgtgt caggacagcg cggcgacgtc ggggtggtcc tggagccagg
     2341 cgcggacggc ctgctgctcc ttgcccttgc cggtctgctg gatcttcgcc tccagaccgg
     2401 tgagctgctc ctcggtgagc ttgaaggagc gcagccaggc ggccacttcg ggttcgtcgg
     2461 cggcgaagcc ctcgcgggcg agggtgtgga tgccgtcgcc cttgccccag acggccttcg
     2521 ggtcctccag cttggtcagc tcgtacgagg agtacgccca gtgcggcgac cacagcacgg
     2581 tgaccaccgg ctccttcttg tcgtaggcgc gcttgagttc ggcgagcatg ccgggggtgg
     2641 agccgtcgac gacctggtac tcgccctcca ggccgtactc cttcatgacc ttgtccttca
     2701 gcagggccat ggcgccggcg ctgggctcga tgccgatgat ccggcccttg aactgcccgg
     2761 acttgccctt caggtcggcg agcgagcgga cgtccttcat gtaggagggc acggcgagct
     2821 cgatggaggt cgggccgtac caggagccga ggtcctccag cttgtcgccg tacttctccc
     2881 agtactgggc gtgggtgacg ggcagccagg cgtcggtctg gaagtcgagg ccgccgccgg
     2941 ccaggccggt gtagagcgcg ccggcctcca gctggcgggt gtcgaccttg aagccgcgcc
     3001 gttccaggag ctccttccag aggtaggtgg aggcgatgcc ctcgtcccac gggatgtagc
     3061 cgatggagac ggtgcggccc ttgccgatgt tgtcggcacc ctccggtccg tcctcgccgc
     3121 cggagccgcc gaaggtgctc aggccgcccg cgaccagggc cagtacgacg gctccggtga
     3181 cggcgtaggc gggctggggg cggtggttcc acacgcgggc ggcgccggtg gcggccgacc
     3241 gggcccgggc gagggtgcgc cggcccagcg gggagacctg gcggccgagc gcgccggtca
     3301 tccggtcgag gtacatggcg aggatgacga tggacaggcc ggcttcgaag ccgaggccga
     3361 tgtcgacgtt gccgatggcc cggtagacgg cgccgccgag gccgccgccg ccgaccatcc
     3421 cggcgatgac gaccatggac aggccgagca tgatgacctg gttgacgccc gccatgaggg
     3481 tgggcagggc caggggcagc tggacgcgga cgagggtgtc gcgcggggtg gtgccgaacg
     3541 cttcggcggc ctcgaccagt tcggcgtcga cctggcggat gccgagttcg gtcatccgta
     3601 cgcccggcgg cagcgagaag acgatggtcg cgatgatgcc gggcaccacg ccgaccccga
     3661 agaagatgat gccggggatg aggtagacca tggcgggcat ggtctgcatg aagtccagga
     3721 gcggccgcag gacggcgctg acccggtcgg agcgggccgc ccagatgccg agcgggatcg
     3781 cgaagaccag ggtgacgagg gtggcgacca ggaccagcga cagcgtggac atggcgtcgg
     3841 gccagagccc gacggagtcg acgagcgcga aaccggcgaa ggcgagcagg cccgcgaaca
     3901 gaccgcgcag ccaccaggcg gcgatggcga ggatgcccgc gaacagcagc ggggcggggg
     3961 cggagaggac ggcgacgagg ccgtcgtaga ggccggtgac gagtgcgctg atggcgtcga
     4021 acagccagga caggcggctc tggaggaagt cgactccgct gtcgacccag gcgccgaggg
     4081 gcaggcgggg catcaggcgg ccacctccgc gcagcggacc ggggcccgct gctcgtcgcc
     4141 gatgaaggcg acgaggcggt cctggggtac ggagccgacg acggcgccgt cggtgccggt
     4201 gacggtgacc gggtgcggga cccgcgcgct gacggcgcac agctcggcca gcggggtgtc
     4261 ggcggtgacg gtgggacagc cgcaggagtc cgcgccgggg cggtgcggcc gggtcgtcgt
     4321 catcaccgcg tccgcggtca gcacccggga gcggtccacg tcctggacga aggaggcgac
     4381 gtagtcgtcg gcggggcggg tgaggatgtc ctcggcggtg ccctgctgga cgacgcggcc
     4441 gtcgcgcatg acggcgatgc cgtcgccgag gcgcatggcc tcgttgaggt cgtgggtgat
     4501 gaagacgatg gtcttcttca gggtgcgctg cagttcgagg agctggtcct gcatgtcgcg
     4561 gcggatcagc gggtccagcg cgctgaagga ctcgtccatc agcagcagct cggcgtcggt
     4621 ggccagggcc cgggcgaggc cgaccctctg ctgcatgccg cccgacagct cgtcgggcca
     4681 ggccatctcc cagccttcga ggccgcacag ggccagcgcc tccgcggccc ggcggtcccg
     4741 gtcggcgcgg ggcacgccct gtacctccag cccgtagccg gcgttctcca gaacgttccg
     4801 gtgcgggaag agagcgaagt gctggaagac catggatatc ttcgtggacc gtacgcggcg
     4861 cagctcgcgc gcgctgagcg cggtgaggtc ctggccgccg aagaggatgc gtcccgcggt
     4921 gggctcgagc aggccgttca gcatgcgcag cagcgtggac ttgccggatc ccgacaggcc
     4981 catcacgacg aagatctggc cgggctcgac gtcgaaggag acgtcgatga ccgcggccgt
     5041 ggctccgtcg gcgcgcagct cgctgcggtc gccgccgcct tcgagtgcgc gcacggcgtc
     5101 gtcgggccgg ttgccgaaca ccttgtagac gtgctcggcc tggagcgtgg acacatacac
     5161 ctcgcgggtc gtaccgggta cggctcgcgc ggatcggtcc ggcgcggccg tggagcggga
     5221 cgggatccgc ccgcatgcgc gtcgcccccc ggcgcagggc accggagggc gaggctccgc
     5281 tccagctgtg ccgatgcccg gcattcactt cggcaaacgc gcgagtgatc cacctcacgt
     5341 gcggggtgcg cggagccggc caggagcggc ccgggggctg tccggccctg acccgccgga
     5401 cactcctaga cgacgcggaa gccggcggcg gcggggtgac ggcggtcacg atggatcgtc
     5461 agatggtccc aggtggggaa ggccaggtcg gtcacggcca ggagcggacc ggacggggcg
     5521 tgcacggtgc ggcgcacggt cagcccgcag gcgggggcgg aggagggggc cgaggccggc
     5581 gggtgcgtgg tgcgggtcat ggtgatggtc tcggcgaccc ggccggccgc cgcggcctgc
     5641 tccagccagc cccggaggga ggccaggtcc cgctcgccgg cgtgcccggc gcggccgcgg
     5701 caggcggcca gctcggggct gcgcgcgacg acgtccgggc tgaagtaggt gacggcgtgg
     5761 cggagcgtct ccccggtccg cccccgctcg cggtggtggt ggaccagggt gcggtccccg
     5821 cccgacatcc cgagcagcac ggcgagcgag ggcgggacgg tgaccaccgt cacccagctc
     5881 cggctgaggg cgggcgcggg ggacgcgggc gcgaaggcca ccggatcggc cgccgcgggg
     5941 acgacctcgg ccgagacggc ggggcgtgag ccgcggcgcc cggtcacgac gaggccgtcc
     6001 tcgcgcaggt actggagggc ggccctgatg gtctgccggt tgacctggta ccgggcggcc
     6061 aggctgcgtt cggagggcag tcttccgccg ggggtgcgcg cggcgcggtc gagatcgcgg
     6121 cgcagcgctg cggcgatccg ctggtacttg ggcatggcgg ccgggccgcc gccccgcgaa
     6181 ggggagggca tggcttctcc tctgacgggt ggtcacggac tgcgcggtgc ccgaccaacc
     6241 tagcattggt ctataccttt gggtgagagg gcatcgcggt acgccgcccg ccttggccgg
     6301 ttcccgaccc ccgtcccggg cgggggccgc cctccctact cgcgcagcgg gttcggcagg
     6361 ggccggtagc gggcgtccgc gccgtcggcg cgggtccagc gcagcagcag gttggtcttg
     6421 gcgggcaggg cgggtgcggc gaggagtccg gcgatctcgg ggagcccgcg cagggagtcg
     6481 tagcgcagca actcctcccg cacggcgggc cagaggagcg gcgagatgtc cggataccga
     6541 tcggccagcg cgcccgcgac ctccgacagg ttgttgacca ccaggcagta caccaggcgc
     6601 tgccaggcgt ccgcccgcgg caggtccggc aggagcttga ccccctccgc gtcccggaag
     6661 agggcctgca cgggcatgcc cgacgcgtcg accgcgacca gggtgttctg caggtgggcc
     6721 tccaggacga cgccgtgccg ggcgaagagt tcgagcaccg gcggcacgac ctggcgcagg
     6781 tacgcccgcc accaggcggc ggggtcggcc gccccggccg gcgggctccc gggatatccc
     6841 tcggcgagcg cggcggccag cagcggcgtc gccccgggca cggtgtgggc gcgcaggccg
     6901 tcacggacca ggacggcgag ttcctcgaag gcgaaggccg cggtgcggta gccgcggtcg
     6961 gcgagccagg ccgcgtccga gccggtccgg cgcagtgcgg cgaaaccggc ctcgacggcc
     7021 gcgtcggtgc ggcgcagctt cagcaggtcg tgccgccaca gccggcgcac gtcgttggtg
     7081 atccgcacgt cgaggctgaa cttcacgaag aggtcggccg cgggacccgg aacgtggagg
     7141 gtccggatgg acgcggtggg ccaggccggg cggcggctcg cgccgagccg cagcagccgc
     7201 ccgtcggcga aggcctcgcg caccgcgggc cggtcctcga ccaggtcgag ctgccaggga
     7261 tgcgcgggca ggagccggta gccggcgggg gcggccggcc cgtcgaggag gccggcgagg
     7321 gagtcgacgg cctcggaggc ggcccgtccg ccctcttcga cgcactggtc ctcgcgcacc
     7381 cccaggaaga ccagcgggaa acgggcgtgc gcctcgggcg cgtacggcag ccagctcccg
     7441 gccggcgccc cgccgcgggc cttgggggcg ggatggtgcg ggtgacccgt caccagggac
     7501 tgctcggaga gcacgtacgg gtccgccggg ggctcggcgc cggcgcgggc ggccagcagc
     7561 gcgaggagcg cgtcgcggct gtcggcgatc tcgaccggga gttcgtcgtt ggtgacgccg
     7621 gtgaaccggc cgagttcgtc ggagacgagt ttgaccagtt cggtgtggct gagcgggtgc
     7681 cagccgttcg ccgtccgcag ttcggggtgt acgggacggc ggccgccgcg cacgcggagc
     7741 agccggccgc tgccccgcag ccggtgcacg gccgctccgg ccggcccggc cccggcgggc
     7801 cccgtgggct cggccgcctc ccggagcagg cagttcagga gcggggcggc ggcgtacgcg
     7861 tcggcggcgg cgttgaggtc cactggttcc attcggtcca tccggtgggc cggtggcccg
     7921 cgaagcggaa ccaccggcca tgatcgtcgg tatccgcaat gattacttga tcatcccgtg
     7981 aagcgacatt ccgaaggcgg agtccagcat gcccattccc tcctccgcgg ccgaagaagc
     8041 cgtcgccgcc gaactggcca ccgtacggcc cgcactcggg cccccgtacg ccgccgcgct
     8101 cggcatcgcc cgggcggccg tgctcacccg gctgtggcgg gccctggcct tcgagccgct
     8161 gccgtgggtc gtgggccggg aggctacgcc ggccggcctg gcgctgctgc tggcgggggg
     8221 ccgccggctg gagggcccga cgccggaccc gtacgcgacc cggccgtacg tggacgagct
     8281 gctgctcgac ggcaggtccc acaatcgggc cgggcggctc gtcagggcgc tcggggtccc
     8341 gcacggggag gagttcgccg ccgagctgga cgccagtacg gcctccctcg cgctctcccg
     8401 cgccggacag ccgcccgccg gggacgacca cggggaccac gcggcgcgcg ccacatggga
     8461 gtgggaacag cgggtggtcg acggccatcc gtaccatccc aactgccgct cccgaccggg
     8521 cttctcggtg gccgagcagc tggcgtacgc gcccgagcac cggccggtgg tggagctggg
     8581 cctggtctcc gtacgggccg aggagtgcct ggtcaccggg gactggccgg cgcgactgcg
     8641 cgacggcggg cggatcctgg tccccgtgca cccgtggcag gcggcgcacg tgctgaagca
     8701 cgagcgggtg cggaccggtt tcgcggcgca tccgctgatg gccctgcgca cgctggcgcc
     8761 cgccgagggc ggcccgcacg tgaagaccgc gctgagcgcc cggctgacct cctcggtccg
     8821 ggacatctcg gtctactcca tcgagacggc ggcggcggtg tccgccttcg cccagggtct
     8881 ggccgagcgg ctcgacgggc ggctgcacat cacccgcacc ctgggtgcgg cgaccgcgca
     8941 cagccccgac ctcgcggccg tgctgcgcga gccgccggag gcgtacgcgg acgccgccgc
     9001 cggtgagcgg gtgctgccgg tggcggcgct gggctgctac ccgccggccc gttcggcggc
     9061 ctggcgggcg cggttcgccc gcctcgcgct gtcggtgtgc ctgcgggtgc tggagctggg
     9121 ggtggccctg gaggcccacg ggcagaacct cctcgtcgtc ctctcccccg acggcgagcc
     9181 cctgcggctg gtctaccgcg acctggccga catccggatc agcccggccc ggctgcgggc
     9241 gcacgggctc gcggtgccgc cgctgtcggg caggctggtc acggacgacg tgaccgtcct
     9301 gcgccgcaag ctcttcgggt ccctgctgac gggggcgctc ggtgccacgg cgggctcggc
     9361 cgcggccttc gccgacgcgc tcgcggtggc ggccgccctg ccggccaccg ccgacaccgg
     9421 ggcgctgctg acggagcggc tgccgactaa ggcgctcacc ctcatgagac tgagtccggg
     9481 ggtccccgga gaccagtggg cggaactgcc caatccgctt attggaggat gatccggggc
     9541 gccgggcggg ctactgttca ggggcatgac agcttcctcg tacctgcact ccgtacgggc
     9601 gtcctacgac gccgtcgccg tcgactgcgc gcggctgctg ggcacggaac tggccgggaa
     9661 gccgctggac cgggccatgc tggccgcctt cgcggagtgt gtgcgcgcgg aggggggcgg
     9721 cgccggccgg gccgtcgccg acctgggctg cgggccgggc cgggtgacgg cgcatctgga
     9781 cggtctgggc gtacgggcct tcggtgtgga cctgtccccg gcgatggtgg cggtggcccg
     9841 ccggacgtat ccggggctgc gcttcgaggt ggggtcgatg tccgcgctgg acgtggccga
     9901 cggggtgctg ggcggggtcc tcggctggta ttccaccctg cacacaccgc ccgcggaact
     9961 gcccgcggtg ttcgcggagt tcgcccgcgt gctggcgccg ggcggtcacg ccctgatcgc
    10021 cttcgaggcg ggcgacgggc gggtccggct ggagcacgcg tacgggcacc ccgtcgacct
    10081 cgacgtgtac cggatgccgc ccggccggac agccgccctg ctggccgggg ccggactggc
    10141 cgaggtggcc cgcctgctcc gcgaaccggc ccccggggag agctgcccgc agggcttcct
    10201 gctggcccgc aagggctgac ggcgcacgga cccggagggc ccgggggtcc cgggggtccc
    10261 ggggtcccgg gggtcggcgg cgtcgaggtg gaagggggtc cgctccacct caccgcgcgc
    10321 gatgcccgtg ccggcgaggc ccgcgtggcc cgcggcgacg agccaggtgc cctccgggcc
    10381 gagcgcggtg gcacgcgcga cgacgtcgtg gaggcccgcg gtgacctcac cccctgtgag
    10441 gctgcgccat gcgtcgtgtg gcccaccagc agttcgtgga cacgggcgac cagtgagtcg
    10501 acggtgtcgg ccgtggatct cctcggacct cggcggtgaa gagcgaaagg ggtgtcccgt
    10561 ctgcggcgat ccccgccggg gcgaagggcg tccgagccag gtcggccgcg tagactgacg
    10621 ggcatggcat gccgcatcag tgagctggtc ctggactgcg ccgagccgga gcggctcgcc
    10681 gagttctgga gcagggtcct cggctacgtc gaactcggcc gcgaggacga cggcggcatc
    10741 gagatcggcc cgcccgacgc cggtttcggc ggcccgcagc ccacgctcgt cctcagcccg
    10801 agcgacgacc cgcggaccgg caagctccgg ctgcacatcg acgtcaacgc caccgaccgc
    10861 gaccagcccg ccgagctgga acgcctcctc gccctcggcg ccagacccgt cgacatcgga
    10921 caggacggca cggagacctg gcacgtcctg gccgacccgg agggcaacga gttctgcctc
    10981 ctccaccgcc gcctcccgcc cctggcaccc tgagcgactg cgggcggatc accggccgag
    11041 aatgagggcc atggggaatc tgctgctgca tctcggccgt acgctcgacg agctggatcc
    11101 gccgcgctgg ggtgatccgg ccgacggggc gacccgcctg gtccgcaagg tgcacgggct
    11161 gcggtccgta cccctgggcg acctgcgtcc ggcggatctg ctcagcctcg tcacgcagca
    11221 ggtggcgctc cccttcgtac tgcccctcga cgtgcggctg ccggccgacg aaccgctgct
    11281 cgacgcctac ttccacgagg gggacctact gctcgcgacc gtgtcggtgc ccgccggggc
    11341 gtgggccgcg ctccccgagc tcgaagcgcg gctgcgggcc gtcatcgcgg agctgcccgg
    11401 ggcggccgtg gacgagctgc cccgcggcgg tgccgaggcg ctggcccagt tcgccgggaa
    11461 ggcctgatca ccagcgcagc ggaagccgtg tcacgccccg catcagcgtg cccgggagcc
    11521 agtcgagcgg gcccgcgtcc gggtccccgg ccagtccggg gaaacgttcc agcagtgagc
    11581 ggatcgcgat ccgcccctcc atgcgggcga gcggcgcgcc gaggcagtag tggatgccgt
    11641 ggctgaaggc caagtggccc ggcccggcgc ggcggatgtc gaacgcctcg ggcccgggcc
    11701 ccggcccggt gaaccgcgcc ggatcccggt cggccgccgc gagggccacc aggaccgagg
    11761 atccggtcgc gatcggcacg ccgcccagct ccagatcggc gccggcgaag cggtacgtgg
    11821 cgtgctgcac gggcccgtcg tagcgcagca tctcctccac cgcgccgtcg atcagcccgt
    11881 ccgggtcggc gcgcagcgcg gcgagctgct cggggtggtc gagcagggcc cgtaccccgt
    11941 tgccgatcag gttgacggtg gtctcgtggc cggcgaccag cagcaggaag gccatgccga
    12001 tcagttcgtc cggggagagc tggtcgccgt cctcgtcgcg ggtccggatc agggcgctga
    12061 gcagatcgtc gcccggttcc cgggccttgg ccgcgacgag ttcgcagagg tacgaggtca
    12121 tctcctccag gacccggggg tgcgcgccga cgccgtcgag cggggcgacg atctcgcccg
    12181 accagtagcg gaaccgagcc cggtccaggt tggggacgcc cagcagctcg cagatcaggg
    12241 tcatcggcag cggcacggcg aaggaccgga tcaggtcgcc ccggcgttcg ggcacggcat
    12301 ccatcgcgtc cagcagtccg tcggtgatct gctggacgcg ggggcgcagc gactcgaccc
    12361 ggcgggaggt gaactcgcgg gccaccaggc gccgcagccg ggtgtggtgc ggcgggtccg
    12421 agtccagcat gttggtggcg acggcgtgga cctgcgcgac ctcgaacagc tcggagccga
    12481 gccagttctt cgaaagggcc gggtggctca gggcctccct ggcctcctcg tggccgacga
    12541 ccagccatgc gcgttcgccg cccagcacca gccggtggac ggggccggcg gcgcgcaggg
    12601 cctcgtagaa ggggtacggg tcggcgttga actcatctgc gtgcgcggtg aggtccacaa
    12661 ggctcatggg tgcagcgtac ggcggcggtt caggacgcga ggggtggtcg tcggggagcg
    12721 ccggatcccc ctgccgcccc ggtccgcaca tatgacgagt cgaaccgttt cagcgatgag
    12781 ccgttcgggg gtcaacgcgg tgcgcgtggg acccgcctgc acggcgatcc ggacggacgg
    12841 tggcaggaaa gaggtatgag cctccatcgg cgccaggtcc tcggcggtgc ggccgcggcc
    12901 gtcctcgcca ccgtcggcgc ggccgccggg ggcccggact acggcgcgct ggcccgcggg
    12961 atcgacgggc ggctggtgct tcccggggac cgcgactacc ccgaggcgcg gcggctgttc
    13021 cagccccgct acgacgccgt ggcgccggcc gcggtcgcct atcccgcgca cgcgcaggac
    13081 gtcgccgtct gcctggactt cgcccgccgc gcggccgtac cggtggtgcc gcgcggcggc
    13141 gggcacagct acgccggctg gtccacccgg accggcgccc tggtcctcga cgccggggcc
    13201 atggccgcgg tggcggtcga gggggacggc gtacggatcg gcgcgggcgc ccggctcggt
    13261 gacgtgcaca cggccctcgc cgggcggggc ctgtccgtcc cgaccgggct gtgcccctcc
    13321 gtcggcatcg ccgggctcac cctcggcggc ggactcggtc tggcctcgcg ggcgtacggc
    13381 accaccgcgg accggctgac cggggcgcgg gtggtcaccg ccgacgggac cgtccgcgag
    13441 gtctcggccg accgggaccc ggatctcttc tgggccctgc gcggcggtgg cggcggcaac
    13501 ttcggcgtgg tgacggagtt ccgcttccgt acccacccgg tcggcgactg cgccttcgcc
    13561 gaactccact ggccggacgg cgcttccgcg ggtgtcctgc gcggctggca gcgctggctg
    13621 gccggcctgc cggacccgtt ctggagccag gtggagttca cggtcgaggc cggcaccgga
    13681 gccgggccgg gggccgcggc cgccgtggtg ccctcggtcc gggtggtgtg cctcgacgga
    13741 cgccaggagc tggaacggca gttgacgcgg ctgtccgacc tggtcggggc agcgccgcgg
    13801 gacagctggg tcgtcgtgcg cagtcacggg gacaccgtgc gggccatgtc gggatgcctg
    13861 gacctgagcg ccgcggagtg ccggctgccg ggcacgctgc ccggccggga cccgcggggg
    13921 cggctcggca gggattccta cgccgcccgc tccgacttct gggcgggggc ggggctgccg
    13981 gacgcggcga tcgacgcggt cctggacgcc gtccggcggt acggggccga cgctccgcgc
    14041 ggcggcctcg gcgtggtgca gttcgacggg gtctgcggcg gcgccgtgaa ccgggtcccg
    14101 gtcggcgcca ccgccttcgc gcaccgggac gccgccttcc tggcgcagta cctcgtctac
    14161 tggcccgaat ccgcgcccgc cgccgacgtg gcccggcacg aggcctggct cgacgggctg
    14221 tggcgggacc tgcgcccatg gtcgagcggc cgggcgtacc agaactacat cgacccgaag
    14281 ctcagcggct ggcgcgaggc ctactacggc ccgaacctcg cccggctgga ggaggtccgg
    14341 cgtgcccacg atccggaccg gctcttccgt ttcccccagg ccgtttaggg agtgtccggc
    14401 atgcgacgta cgttgacggt ggccgcggcg gcggccgccc tgctggtgtc cgcggggccg
    14461 ctgcccgcgg ccggggcggg gagcgccgcg gccgctccgg cggccgcggg ccggtggggc
    14521 gcgcacgagg cggagtcctg gtggacgccc gagcggatgg cgtcggcccg ccccctgcca
    14581 cccgttcccc cgctgccggg cgaggaaccg cagacccccg ccgacccggt gcagatccca
    14641 cccgtcgaac ccccggtccc accggtcgag ccgccggtcc caccggtcga gccgccggag
    14701 ccggccccgg tggccacgcc ctcaccgtcc gggaccccca ccgtggccgc gcccgagccc
    14761 gagcccgctg ggacgccgaa catccttccc gcgcccgagc ccgctgggac gccgagcatc
    14821 cttccggccc ccgcgcccgt acgtccggcc ctcccccgca tcccggccgc cggccccggc
    14881 gtcgggcagg acttcggcgg cctcccggtc gtcggccgga tgttcctcgt caagggcggc
    14941 ggctcctact tctgcaccgc gagcgtggtc gcctcccccg gccgcaacct cgtcgtcagc
    15001 gcagcgcact gcctgctcgg cgccgacacc cagcaggtgg ccttcgtacc tcagtacacg
    15061 cgggccaaac cgcggccgtt cggcatgttc ccggtggtgc ggacggcggc cggacgctcc
    15121 aagatctgga tcgaccagcg ctaccgcacc cagggcgtca accgcgcggc cgccctcgac
    15181 gtggccttcg cccaggtcgg acccggagcg aaggggctcc gggtgcagga cgtggtcggc
    15241 ggcaaccggc tcgtcaccgg cgccggttac gcgcacgccc gggccacgct gatcgggcac
    15301 ccgtcgaccg ccgcccggcc gcgcctgtgc gtcaaccgga cgacgaagta caccagcacc
    15361 gacagccgga tcccgggctc gttcctgcgc atcgcctgca ccggctaccc gggcggcacc
    15421 agtggcggcc cgttcctgct gcggctcgac ggccgcaccg ggaccggcga cgtggtgggc
    15481 gtgatcggcg gctggaagac gggcggggac aagcccgacg tctcgtacag ctcctacttc
    15541 ggcacggaca tcaggaagtt gtacgagaag gcggttgccg gggcgaaggc gtcgtgaggg
    15601 cccgtaccca ccgggtcctg cgggggttgc cgaccgtgcg cgggaccgcc gggagcccgt
    15661 cgccggtcag cagctcggcg ggcgcgaggc cgagccggcg gcgcaggtcg gccagggccg
    15721 cgtggacggg cgcgaggacc acctcggcgc ccggggcggc ggaggcgagg gcgtacgcgg
    15781 tggtctcgat cgcctcggcg gcgtcctcgg ccgcggtccg gctccaccct cccggcgccc
    15841 cgggccccca gggcgcgacg gtgtcgtaga ggtggcaggc ggcatcggcc gcggcgtcgg
    15901 cccgttcccc gacgcccggc gccgcgatgg tcggcagttc catgccggtt caacgagccg
    15961 gtcccgcccg ggggtacgta cccgacggcg ccggctcgcg ccgcccgcgc ggcagacgac
    16021 cggcggcgat cgggcggcgc gcgctcaggc ggcgaccgtc tgcagccaca ggggcagcag
    16081 caccagcgac acgagcgagg tcttgatcac gaccgaggcg gagaggtcca cgcccacgtc
    16141 gtagcgctgg gcgaagatga acaggttctg cggggtcggc atcgccgcga tcagcacgag
    16201 gtacgccagc cagtcgcccc gcaccccgaa cagcagcccg cacaccgccc acgccagcag
    16261 tgggaacgcc aggcacttga acccgatcag ggccagttcc tcgcgcgtcg tgccccgcag
    16321 gtggaggccg acgccgccga ggtgcaggcc gagggcgaac agggcgaccg gcgaggcgct
    16381 gttcccgacg aaggcggctc cctccagggc cacggccggg acccgcaccg acagcaggtt
    16441 gagcaggatg cccgcgttgc aggcgaggac cagcggggtg gcgagcgagg cgccgacggc
    16501 ccgggacagg cggcggcccg ggccgccctc tgcgggtccg gcgcggccca gttccatgag
    16561 ggcgatgacg accagggaca gtacgcagac ctggaagagc aggatcggga agatcggcgc
    16621 ggccgtcccg aagacggtga tgaacacggg gacggcgaag taggcggtgt tcacctggac
    16681 tccggccatc acgcgcaggg ccacggcgcg cggctcccgc cggccgcggg cgaccgccgc
    16741 cacggccacg accgccacgg cggccgccgc ggcggccgcg tacccgccta tcgcccgcca
    16801 gttgaacagg gcggcgaggt cgctggcgta gatgttcccg aagaggtagc agggcatggc
    16861 gaagaggaag gcgtagtcgg agaagacctt ggccgcctcg gccggaacga ccttgcggcg
    16921 cgccaggagg actccgccgc cgaaggccag cagcaccggc accagcttct ccagcgcggc
    16981 cgccccgccc at
//
