LOCUS       reptomyces_RBGC_301304 16767 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_301304
VERSION     Streptomyces_RBGC_301304
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_002080455.1
  ORGANISM  GCF_002080455.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..324)
                     /protein_domains="PF01817"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133685"
                     /pseudo=False
                     /translation="VTNPTPESLLQPFRERLEALDQQLAELVAARLAICCEVAEVKRAN
                     GIPMMQPNRVAAVREAYAARGERLDLSPDFMRSLATLLIDEACRLEDEIIDAPAAAGAE
                     ALR*"
     CDS             complement(322..1256)
                     /protein_domains="PF00850"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133686"
                     /pseudo=False
                     /translation="MTLHVVIPEESAALPFTVEPSGAQVASKEIPERIHHILAGLLDGG
                     AVAAALGEDSLARAERLVGAVHDKELLDHLRHGVPEGAESVLDSAFSAPGLEQETPVTR
                     GVWPAALGAAAAAVRAAELTARDGENSYALVRPPGHHAGPGWYGGYCFVNNAVVAARTL
                     QEEGVARVGILDVDYHLGNGTLALVQGDPTLPFASVHSSDPKDFPYTFEPGPGLFGIRS
                     DPAQEDFLALVADALAHLRREGAAALVVSVGYDVLAGDPHGSWTLAPEVFGPVAALIAE
                     QRLPTVFVQEGGYGIPSLRGAARALALEAS*"
     CDS             complement(1254..1729)
                     /protein_domains="PF00583"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133687"
                     /pseudo=False
                     /translation="MSTLEFETGPAKPEEAQAVAEAVTTLLRELRQDDTHTIPGLDGAV
                     DAAIAGRDGSGVLVARDGQGRVVGVLGYTTQTALRLAAPYRHVQELWVEPALRSRGVAA
                     LLLEALDGLCAADGVRRVEVCLPGEQFPSFPRTRAFYERSGFRVIGPRVIKDLS*"
     CDS             complement(1727..3735)
                     /protein_domains="PF00425"
                     /protein_domains="PF00117"
                     /protein_domains="PF04715"
                     /protein_domains="TIGR00553"
                     /protein_domains="TIGR00566"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133688"
                     /pseudo=False
                     /translation="VIDLRILLVDNYDSYTWNLFQLIWKVAGVPPVVVRNDEATADELL
                     GQDFTHVVISPGPGTAARDEDFGLCRDLLEQATVPVLGVCLGHQGLALAFGGDVRHAPE
                     IVHGQTSAITHTGTGVFAGVPQGFRAVRYHSLTVTEPLPADLVATAWSEGGLLMGLQHR
                     ERPLYGVQFHPESVDSEYGEEIIANFLGVTPTLRWSELDVELDTEGLFLRAFAESPYSF
                     WLDSSRTAYGMGRYSYLGACAGDGLEVLRAYAGAGIVERETHEAMERLSGTVFEHLRAG
                     LATTPVAAGASPVPFAGGYLGYLGYGIKGSVGIGRPGSGERPDAELLRVDRFVAYDHEA
                     GRRYLITVGLCAEEHDAWCEEVRALARRPLVPRPRRETAPAVLEPGVDRETYLEHFDTV
                     QQWLRDGDSYEACYTYQISGTSEADPLETYLRLRATNPAPYAAYVRLGERSLLSSSPER
                     FITVAGSGEVEAKPIKGTAPRHADPVADEAARAALETDRKIRSENLMIADLLRNDLGQV
                     CDTGTVHVPKLMAAESYATVHQLVTTVRGRLRADRGAVDCVEALFPGGSMTGAPKKRTV
                     ELLDELEPQERGVYSGSLGFFGFDGAADQSIVIRTIVWEGNRVRIGVGGALIVLSDGEE
                     EFQETRLKARALLRVLGVDELHEATSGTAARYQG*"
     CDS             complement(4145..5460)
                     /protein_domains="PF00202"
                     /protein_domains="TIGR00508"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133689"
                     /pseudo=False
                     /translation="MSSAMPPPLDPEQLVALDRAHVWHPYAPMPGRTDPVVVESASGVR
                     LRLARPAEGSDELIDGMSSWWAAVHGYGHPVLDEAVRDQLGRMSHVMFGGITHEPAVRL
                     AAKLVEITPDPLRHVFLSDSGSVSVEVAVKMCLQYWRSLGRPAKRRLLTWRGGYHGDTF
                     QTMAVCDPDGGMHSAWAGLLPDQVFADRPPAGFDAGVDQEYAAHLAELFERHAHELAAV
                     IVEPVVQGTGGMRFHSPGYLRLLRELADAHDVLLIFDEVATGFGRTGELFAADHAGVTP
                     DVMCLGKSLTGGYLSMAATLCTPRIAEGISRGELPVLAHGPTFMGNPLAAAVAVASIEL
                     LIRDDWRTQVKRIEAELRTNLEPARALPGVVDVRVLGAIGVVQLDHDVDVTAASRAAMR
                     AGVWLRPYRDMVYTMPPFITGDKDLARIAEGVLAAVEAG*"
     CDS             5493..5653
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MAALRRNRAPTSGPNITTGPIHSSHIYSWGVGIDLKSTSLPDQVV
                     GRTALFGH"
     CDS             5832..7060
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133690"
                     /pseudo=False
                     /translation="MPHKVILALLAIGSFAVGTDGFVISGILPRIAGELDVSEPVAGQL
                     VTAFALSYAISAPVLMTLTAGLSRRVMLRGSMLAFLLANVLGAVAPTYGVLMAARILAG
                     ISAALYMNTAAATATALAGERYRGRAVSLIIGGLTVATALGVPGGTLVGQLGSWRLTLA
                     LVVVLAVPVFIGLFLVLPAVPQPPVISMRDRLRIGAQRPVLLSVLANLFAVAGCFTVFT
                     YLAAFTRATTGMDDAQVSIVLLVFGVAGAFGNAVGGRLSDRIGAERTFTGAVSGVVVSM
                     VLLAVLASWFASGSTVVGLVFLAVTVLWGTLYWAEPPTAIHRVLDLAPTAPSVAISVNS
                     SASYLGVALGGAVGGAVLDRLSPAALAWAGACLELIALALVVLPRTSAARKGRAGHVPV
                     GPLPEPAREV*"
     CDS             7173..7414
                     /protein_domains="PF00550"
                     /protein_domains="TIGR00517"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133691"
                     /pseudo=False
                     /translation="VANDDVFDRLTTCTVDVLQVKPESVTPDASLTEDLGASSLIQVEL
                     VMAIEEEFGISVPDESVEEIRTVDDLHRLILSLVA*"
     CDS             7415..8595
                     /protein_domains="PF00109"
                     /protein_domains="PF02801"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133692"
                     /pseudo=False
                     /translation="MNGKDNGGRRVAVTGIGVVSACGTGAEAFWEGLFRTPPDGHRELA
                     DWDPSPWMEVREARHTDRFTQFAVAAADMAHRDAGLTEVDAERSGVVVATALAGVSTFE
                     RQSVIHHERGGRRVSPFLVPMMMANAAAATVAMRQGWRGPCESLETACAAATHAIGHAA
                     RMIADGTCDRVLAGGTEAAITPTIVAGFTNMRALSSTGRTRPFDTDRDGFAIAEGAAVL
                     VLEDWDTAVARGATLYGEVLGSASTADAHDITMPAPGGGEAARCIRLALEDAGVRPQDV
                     GQINAHGTGTLRNDEAETNAILSVFEECPPVTSTKGATGHAFGAGGALEAVAVLLSMRH
                     GRIPPTVGLTTVDPALAVDVVTGEGRTWQPGPALTQSFGFGGHNGVLVLGPAG*"
     CDS             8612..9774
                     /protein_domains="PF00155"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133693"
                     /pseudo=False
                     /translation="MAAERKSDPHDVFAWIDDSTRRRDRAGLTRRIQVRGPRPNVIDFG
                     GNDYLGLTRHPDVVRAVADASLTWGAGSTGSRLATGTTEVHAELERELAEFSGAEAALV
                     FSSGYLANLGAVTVLARPGTLIASDAFNHASLIDGYRLSGADVADVEHADPQALERVLA
                     AREQQRAVAVTESVFSVDGDLVDLGAVLEVCRRHGAGLLVDDAHGFGVIGAKGEGAVAA
                     AGLAGHPDVVTTITLSKSLGAQGGAVIGPRRVIDHVMNMARSFLFDTGLAPASAAGALA
                     ALRVLRAEPDRPARTRAVAVALAERLAAAGLPVTEAQAAVVSVRGPSAAQTAQWAQDCL
                     DDGLKVACFRPPSVPDRFSRIRLTSRADLTEAEIDRAIDVVVKHSPW*"
     CDS             9837..11392
                     /protein_domains="PF00501"
                     /protein_domains="PF13193"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133694"
                     /pseudo=False
                     /translation="MTIAGGFLAHTTKSPDRAALAVGDAAGRRWSYGALRRGALAVARA
                     LRAEFGPAPGPAVRVAVLLGNREEFPRIFLGAAVAGIPVMVLDPAWSAAELAAVLSDTP
                     PARLFCESADGPLARLLPPDALVEVAGGGLEAWLRPHHEEPREPDADADARQEFAEVPH
                     GAPFYVGFTSGSTGRPKGVVRSHRSWLRTFDRYTAEFGIGAGDTVLLPGSLAHSHFLFG
                     LVHGLHVGATVRLMPAFDAGRALDHIERHGVTRLYLVPTMFQALLEHARRQPGRRFPAV
                     RSLLSVGAKWSPASRATAADLFPNADAVEFYGSTELSLVSVLHGDDDGPRESVGRPVAG
                     VELSLRTPSGEAAGVNEPGQVHVRSDMLFTRYLSADHVEAPDADGWFTVGDIGRVDERG
                     YLHLVGRKQGMLISGGLNVYPEEVTAALLRLEEIAEAAVVGLPDERWGDLVCAVVRWRR
                     GARLGLAELRERASAHVSRQKCPRRLFETDELPHTSSGKIDHGRVRSLLLDGRHSMREV
                     R*"
     CDS             complement(11438..12684)
                     /protein_domains="PF00067"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133695"
                     /pseudo=False
                     /translation="MLAMPVDSVDLFDQGYALDPYPAMAALRENEPVKFDENTGLWLIS
                     RYEDVRSILLDPENFLPDNAIDAIGRFSVQTLRVLARVRFDLPQTLANNSSDSHAGYRR
                     IMTKLFNAQAVNASMPMVEKVVAEALDDVEGRLAADGTCDLATTIARDVPFRVMLRLLG
                     LESAIDVDIDTLARWSDASLELFWGRPRGEREVALAREAAAFYSWLTDLVSQPAPEAGT
                     LLGALAEHRLPDGEPLGVTQKAAVVYFMIIAGQMTTTQMLSTMYRRALREPGLWQQFAA
                     EPATVAPWTEEVLRRDPPITTWRRVTGRPMTLSGVELPAGAPLLLMLSSTGSDTEVFEK
                     PEQLCPYRSNVRKHLSFGIGRHRCSGAELARMEADVVMRMTAARLPDLRLSDGTSPRML
                     ALLSFRAPLQVLVERG*"
     CDS             complement(12895..13454)
                     /protein_domains="PF01382"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133696"
                     /pseudo=False
                     /translation="VSHMRKIVVAAIAVSLTTISITASASADPSKDSKAQVSAAEAGIT
                     GTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSTPATDGSGTALGWTV
                     AWKNNYRNAHSATTWSGQYVGGTEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKPS
                     AASIDAAKKAGINNGNPLDAPQQ*"
     CDS             complement(13780..14888)
                     /protein_domains="PF14269"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133697"
                     /pseudo=False
                     /translation="MTVDQNTVRRRGVGLIAHDPERSYGGLTLYTPITSAGEIHLVDIE
                     GRPAHTWNSPHPPGRQAQLLPGGNLFYAAKDTTGPTLFPIWDVYHGGIFQELAPDSTVL
                     REVRHPFHHHDASILRNGNLIIGAVEPLDPADAARIRGGIPGSEAPGGVIYGDVVYELT
                     WEGEIVWRWAAIEHLDPEEVPLNRHFARNHWPMANTVNESADGSIVVGFRSASTTVSVD
                     RADGSVQWRIGPDVLAQQHHPHELPGGTLLVFDNGTYRDTTSVPYSRVLELDPHTGTEV
                     WSYEDNPPQNFFSPYMSSAQRLPNGNTFVAEGSFGRLFEVTPDGDVVWEFVVPQFRSFG
                     EGVGLESSAGAQNSVFRAHRYAAEQIPWL*"
     CDS             complement(14942..15939)
                     /protein_domains="PF09084"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133698"
                     /pseudo=False
                     /translation="MPGPRAVAAVLLAALLSPLATACAGSPSGTAAGDRPAVTLAASDY
                     LGGAPVHVAEDGDLWAAEGVRATVTTQPTGRDALNAVLGGQAQLGVVGDLPAVTAALGG
                     RELRVVADLSRFSDWRLLTRTDRQITGFAALKGRKVGVPQGTNVEYALSRMLASAQLTA
                     ADVTVVNLAPNQVTSALARGDIDAGVTFPSFYDAARTALGGSYAELPFTGYTARTLLVA
                     GPSANEESTTAVLRTLLRAQRELGADPARARKAVLTQSKGALQAAYVDAYQPRYTYGAT
                     LSPELLAQLEEEAAWAKAAQKLPGAADRAALLRYLNPGPLTAADPAAVTVR*"
     CDS             complement(16049..16767)
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_133699"
                     /pseudo=False
                     /translation="MSLEVRLEGLSAGYGSAAPVLERTDLEFPAGSFTALLGPSGCGKS
                     TVLNLVAGFVRPTAGRVTAGSEPVRGPGPERGVVFQHYALFPWRTARGNVEFALKRLGL
                     PRAERRRRALAALAEVGLADGAQKYPAQLSGGMQQRVALARALAAEPEVLLMDEPFGAL
                     DALTRTRMQSLLRELWQRRGTTVLFVTHDIDEALALAGRVIVLGGSPGRVLADHAVPAG
                     APDPDLRSLIARHLGSE*"
ORIGIN
        1 tcatcgcagt gcctccgcgc cggcggccgc gggagcgtcg atgatctcgt cctccaggcg
       61 gcacgcctcg tcgatgagca gggtcgccag tgagcgcatg aaatcgggtg acaggtccag
      121 ccgttcgccg cgggccgcgt acgcctcgcg gaccgcggcg acccggttcg gctgcatcat
      181 cggaatgccg ttggcccgct tgacctcggc cacctcgcag cagatcgcca ggcgcgccgc
      241 caccagttcg gccagctgct ggtccagtgc ctccagccgc tcccggaacg gctggagcag
      301 gctttcggga gtagggttcg tcacgaggcc tccagggcca gggcgcgcgc ggcgccgcgc
      361 agggacggga ttccgtatcc gccctcctgg acgaagacgg tgggcagccg ctgctcggcg
      421 atgagcgcgg cgacgggccc gaacacctcc ggtgcgaggg tccaggagcc gtgcgggtcg
      481 cccgcgagca cgtcgtagcc gaccgagacc accagtgccg cggccccctc acggcgcagg
      541 tgcgccaggg cgtcggcgac gagcgccagg aagtcctcct gggccgggtc ggaccggatg
      601 ccgaagagac ccggccccgg ttcgaaggtg tacgggaagt ccttcgggtc gctggagtgc
      661 accgaggcga acggcagggt gggatcgccc tggacgaggg cgagggtgcc gttgcccagg
      721 tggtagtcga cgtcgaggat gccgacccgg gccactccct cctcctgcag ggtccgggcg
      781 gcgacgacgg cgttgttgac gaagcagtag ccgccgtacc agccggggcc cgcgtggtgg
      841 cccgggggcc gcaccagggc gtagctgttc tccccgtcgc gggccgtcag ctcggccgcc
      901 cggaccgccg cggccgctgc ccccagcgcc gccggccaca ccccgcgggt gaccggtgtc
      961 tcctgctcca ggccgggggc cgagaacgcg ctgtcgagca ccgactcggc gccctcgggc
     1021 accccgtggc gcaggtggtc gagcagctcc ttgtcgtgca cggcgcccac cagccgctcg
     1081 gcgcgggcca ggctgtcctc gccgagcgcg gcggcgaccg cgcccccgtc gagcagaccg
     1141 gccaggatgt ggtggatccg ctcggggatc tccttgctgg ccacctgggc accggacggc
     1201 tcgaccgtga acggcagcgc cgcggactcc tcgggtatca ccacatgcag cgtcatgaca
     1261 gatccttgat cacgcgcggg ccgatgacgc ggaaaccgga gcgctcgtag aacgcccggg
     1321 tccgcgggaa ggaggggaac tgctcgccgg gcaggcagac ttcgacccgc cggaccccgt
     1381 cggcggcgca cagcccgtcg agggcctcca gcagcagggc ggcgacgccg cgggaacgca
     1441 gcgccggctc cacccacagc tcctggacgt gccggtacgg cgcggcgagc cgcagggcgg
     1501 tctgggtcgt gtaccccagt acgccgacca cgcggccctg tccgtcccgt gcgaccagca
     1561 ccccggagcc gtcccggccg gcgatggccg cgtccacggc tccgtccagc ccggggatcg
     1621 tgtgggtgtc gtcctggcgc agctcccgca ggagggtggt gaccgcctcg gcgacggcct
     1681 gtgcctcctc cggcttcgcc ggaccggtct cgaattcgag cgtgctcatc cctggtacct
     1741 cgcagccgtt cccgatgtgg cctcgtggag ctcgtcgacg cccaggaccc gcagcagcgc
     1801 gcgggccttg agccgtgtct cctggaactc ctcctcgccg tcggagagga cgatgagcgc
     1861 cccgcccacg ccgatgcgca cgcggttgcc ctcccagacg atggtgcgga tgacgatgga
     1921 ctggtccgcc gccccgtcga agccgaagaa cccgaggctg ccggagtaca ccccgcgctc
     1981 ctgcggctcc agttcgtcca gcagctccac cgtgcgcttc ttcggcgcgc cggtcatcga
     2041 gccgccgggg aagagcgcct ccacgcagtc gaccgcgccg cggtcggcgc gcagccgccc
     2101 gcgcaccgtg gtgacgagct ggtgcacggt ggcgtacgac tcggccgcca tcagcttggg
     2161 cacgtgcacc gtgcccgtgt cgcagacctg gccgaggtcg ttgcggagca ggtccgcgat
     2221 catcaggttc tcgctgcgga tcttgcggtc cgtctccagg gcggcgcggg cggcctcgtc
     2281 ggccaccggg tcggcgtgcc gcggagcggt gcccttgatc ggcttggcct cgacctcgcc
     2341 gctgcccgcc accgtgatga agcgctccgg cgaggagctc agcagcgagc gctcgccgag
     2401 gcgcacgtac gcggcatagg gcgccggatt ggtcgcccgc agccgcaggt aggtctccag
     2461 cgggtcggcc tcgctggtac cgctgatctg gtacgtgtag caggcctcgt acgagtcgcc
     2521 gtcccgcagc cactgctgca cggtgtcgaa gtgctcgagg tacgtctccc ggtcgacgcc
     2581 gggctccagc acggccggtg cggtctcccg ccggggccgc ggcaccaggg ggcgccgcgc
     2641 gagcgcgcgg acctcctcgc accaggcgtc gtgctcctcg gcgcagagcc ccaccgtgat
     2701 caggtagcgc cggccggcct cgtggtcgta ggcgacgaag cggtcgaccc gcagcagctc
     2761 cgcgtccggc cgctcaccgc tgccgggtcg gccgatgccg acgctcccct tgatgccgta
     2821 gccgaggtag ccgaggtagc cgcccgcgaa cggaacgggc gaggcgccgg ccgccacggg
     2881 ggtggtcgcg agccccgccc gcaggtgctc gaagaccgtg ccggagaggc gttccatggc
     2941 ctcgtgggtc tcgcgttcga cgatgccggc gcccgcgtag gcgcggagca cctccaggcc
     3001 gtccccggcg caggcgccga ggtagctgta gcggcccatc ccgtacgccg tgcgcgagct
     3061 gtcgagccag aagctgtacg ggctctccgc gaaggcgcgc aggaacaggc cctcggtgtc
     3121 gagttcgacg tcgagttcgc tccagcggag cgtgggcgtg acgccgagga aattggcgat
     3181 gatctcctcg ccgtactcgc tgtccaccga ctcggggtgg aactgcaccc cgtacagggg
     3241 ccgttcgcgg tgctggaggc ccatcagcag cccgccctcg gaccaggccg tcgcgacgag
     3301 gtccgcgggc agcggctcgg tgacggtgag ggagtggtag cgcacggccc ggaagccctg
     3361 cggtacaccg gcgaagacac cggttccggt gtgggtgatc gcactggtct gcccgtggac
     3421 gatctccggc gcgtgccgga cgtcgccccc gaaggccagc gccaggccct ggtgtccgag
     3481 acagacgccg aggacgggca cggtcgcctg ttccaggagg tcccggcaga gcccgaagtc
     3541 ctcgtccctg gccgcggtgc ccgggcccgg ggagatcacg acgtgggtga agtcctgtcc
     3601 gagcagttcg tccgccgtcg cctcgtcgtt gcgaacgacg acgggaggca cgcctgccac
     3661 cttccatatc agctggaaga ggttccacgt gtaggagtca tagttgtcta cgagaaggat
     3721 ccgcaggtct atcacgatgt ggtcgagctc cttgatggcc ggaacggcct tttgggcaca
     3781 gtgatccggc tgaccgactt ttctatcggt ggtgattcat cggtgatgtg aatcgatggc
     3841 gctgaattga gcgcacgtcg gcatgcccgg gcggatgcgc atggctatgc ggatgaaact
     3901 gacattttct agcccccgta atgtctgtca cagctcggat cattcagggc gcacgttgtg
     3961 ctcgtgtggc cggtgcgccg gtccgagaag gtcgttccaa cgttcgatgc tagccatgcc
     4021 gggccgaata tgcatccccg tgtgacccaa cccacttgcc acctgcggga acgcggtgag
     4081 ttgttactcg agtcagttgg cggagcatca gaacggaatg ctgcattcag tactgagggc
     4141 gcatcagccc gcctccacgg ctgccaggac accctccgcg atccgggcca gatccttgtc
     4201 accggtgatg aacgggggca tggtgtagac catgtcgcgg taggggcgca gccacactcc
     4261 cgcgcgcatc gcggcccggg aggccgcggt cacgtccacg tcgtggtcga gctggaccac
     4321 gccgatggcg ccgagcaccc gtacgtcgac cacgcccggc agcgcccggg ccggctccag
     4381 gttcgtccgc agctccgcct cgatccgctt gacctgggtg cgccagtcgt cccggatcag
     4441 cagctcgatc gaggcgaccg ccaccgcggc ggccagcggg ttgcccatga aggtcggtcc
     4501 gtgcgcgagg acgggaagct cgccgcgcga gatgccctcg gcgatccgcg gggtgcagag
     4561 cgtggcggcc atggacaggt atccgccggt cagggacttg cccagacaca tcacgtcggg
     4621 ggtgacgccg gcgtggtcgg cggcgaacag ctcaccggtg cggccgaaac cggtcgccac
     4681 ctcgtcgaag atcagcagca cgtcgtgggc gtcggcgagc tcgcgcagca gccgcaggta
     4741 gccgggggag tggaagcgca ttccgcccgt gccctgcacc acgggctcca cgatcacggc
     4801 ggccagctcg tgcgcgtgcc gttcgaagag ttcggccagg tgggcggcgt actcctggtc
     4861 cacgccggcg tcgaagccgg ccggcgggcg gtccgcgaac acctggtccg gcagcaggcc
     4921 cgcccaggcg ctgtgcatcc cgccgtccgg gtcgcacacg gccatcgtct ggaaggtgtc
     4981 gccgtggtag ccgccccgcc aggtcagcag ccggcgcttc gcggggcggc cgagggagcg
     5041 ccagtactgc aggcacatct tgaccgcgac ctcgaccgag accgatccgg agtcggacag
     5101 gaagacgtgc cgcagcgggt cgggggtgat ctcgacgagc ttcgcggcca gccgtacggc
     5161 gggctcgtgg gtgatgccgc cgaacatcac gtggctcatc ctgccgagct ggtcgcgcac
     5221 ggcctcgtcc aggaccgggt gtccgtagcc gtggacggcc gcccaccacg aggacatgcc
     5281 gtcgatgagt tcgtcggagc cctcggcggg ccgcgccagc cgcagccgga cgcccgaggc
     5341 ggactcgacg accaccgggt cggtgcgccc cggcatgggg gcgtaggggt gccatacgtg
     5401 ggcccggtcg agggcgacga gttgctcggg gtccaggggc ggcggcatgg ctgaagacat
     5461 gggatccgaa tcctcctgac ggttcgtcct cttggcggcg cttcgccgga atcgggcgcc
     5521 gacaagcggt ccgaatataa cgaccggccc gattcattca agccacatct actcttgggg
     5581 agtggggatt gacttgaaat cgacttccct tcctgatcaa gtcgtcggca gaacagcgct
     5641 tttcggccac tgatcggggt gatcgccctc acgttaatgc cgttattgtc gtgacttgat
     5701 tgctggtacg ttgatccgaa caaccccgtt cgtaaagtcg gttcacgaga ccggctcgac
     5761 ctgaaagggg agctggaaaa attcacgatc ctgacatgcg tgatcccgcg cagggtcccc
     5821 gggaggcgtc atgccccaca aggtgattct ggcgcttctc gccatcggct cctttgccgt
     5881 cggcaccgac ggttttgtca tcagtgggat tcttccgcgt atcgccgggg aactggacgt
     5941 gtccgaaccg gtggccggac agctcgtcac ggccttcgcc ctgagttacg cgatcagtgc
     6001 cccggtcctg atgaccctga ccgccggcct gtcccggcgg gtcatgctgc gcggctcgat
     6061 gctggccttc ctgctcgcca acgtgctggg cgccgtcgcc cccacctacg gggtgctgat
     6121 ggctgcccgg atcctggccg ggatcagcgc cgcgctctac atgaacacgg cagcggccac
     6181 cgcgaccgct ctcgcggggg agcggtaccg cggccgggcg gtctccctga tcatcggcgg
     6241 gctcaccgtg gccaccgcgc tcggggtgcc cggaggtacg ctggtcgggc aactcggcag
     6301 ctggcggctc acgttggcgc tggtcgtggt gctcgccgtg cccgtgttca tcgggctgtt
     6361 cctggtgctg cccgccgtgc cccagccgcc ggtgatcagc atgcgggacc ggttgcggat
     6421 cggcgcacag cgtccggtgc tgctgtccgt cctggccaac ctgttcgcgg tggcgggctg
     6481 tttcaccgtc ttcacctatc tggccgcctt cacccgggcc acgacgggca tggacgacgc
     6541 gcaggtgagc atcgtcctcc tggtgttcgg tgtggcgggc gccttcggca atgccgtcgg
     6601 cggccggctc agcgaccgca tcggcgcgga acgcaccttc accggtgcgg tgtcgggcgt
     6661 cgtggtgtcg atggtgctgc tggccgtgct cgcgagctgg ttcgcctccg gatcgacggt
     6721 cgtggggctg gtgttcctcg ccgtgaccgt cctctggggc acgctctact gggccgaacc
     6781 gcccaccgcc atccaccgcg tgctcgacct ggcgccgacg gcgccgagcg tggccatctc
     6841 cgtcaacagt tccgcctcgt acctcggcgt ggccctgggc ggcgccgtcg gcggcgccgt
     6901 gctcgaccgg ctctcgccgg ccgccctggc atgggcgggc gcgtgcctgg agctgatcgc
     6961 cctggcactg gtcgtcctgc cgagaacgtc cgcggcccgc aagggccggg cgggacacgt
     7021 gcccgtcggc ccgctgccgg agcccgcacg cgaggtgtga cccggtgtga tctccaagac
     7081 ttccggctcc gggcgccgac acggccgccc ggaagccggg gaagcaacaa ccacagataa
     7141 ttcatcttat tttgggggag gttggccacc cgtggctaac gacgacgttt tcgaccgcct
     7201 caccacctgc acggtggacg tcctgcaggt caagcccgag tccgtgaccc cggacgcgag
     7261 cctgaccgag gatctcggcg ccagcagtct catccaggtg gagctggtca tggccatcga
     7321 ggaagagttc ggcatctcgg tacccgacga gtccgtggag gagatccgga ccgtcgacga
     7381 cctgcaccga ctgatccttt cgctggtcgc gtgatgaacg gcaaggacaa cgggggacgt
     7441 cgcgtcgccg tcaccggcat cggtgtcgtg agcgcctgcg gcacgggggc ggaagccttc
     7501 tgggaaggcc tcttccggac accgccggac ggccaccggg aactggcgga ctgggatccg
     7561 tcgccctgga tggaggtccg cgaggcccgg cacaccgacc ggttcaccca gttcgccgtc
     7621 gcggccgccg acatggccca ccgcgacgcg ggcctcaccg aggtcgacgc cgaacgcagc
     7681 ggggtcgtcg tcgccacggc cctggccggc gtcagcacat tcgaacggca gagcgtcatc
     7741 caccacgagc gcggcgggcg ccgggtctcc cccttcctcg tgcccatgat gatggccaac
     7801 gccgccgccg cgacggtggc catgcgccag ggctggcggg gcccgtgcga gagcctggag
     7861 accgcgtgcg ccgcggccac ccacgccatc gggcacgccg cccggatgat cgccgacggc
     7921 acctgtgacc gggtgctcgc cgggggcacc gaggccgcca tcacacccac catcgtcgcc
     7981 ggattcacca acatgcgggc cctgtcctcc accggccgca cccgcccctt cgacacggat
     8041 cgcgacggct tcgccatcgc cgagggcgcc gcggtgctcg tgctggagga ctgggacacg
     8101 gcggtggccc gcggcgccac cctgtacggc gaggtcctcg gctcggccag cacggccgac
     8161 gcccacgaca tcaccatgcc cgcccccggc ggcggcgaag ccgcccggtg catccgcctc
     8221 gccctcgagg acgcgggcgt gcgcccgcag gacgtagggc agatcaacgc ccacggcacg
     8281 ggcaccctgc gcaacgacga ggcggagacc aacgccatcc tgtcggtgtt cgaggagtgc
     8341 ccgccggtga cctccaccaa gggggccacc ggccacgcct tcggcgccgg cggcgcgctg
     8401 gaggccgtcg cagtgctgct gtccatgcgg cacgggagga tcccgccgac cgtcggcctc
     8461 accaccgtcg acccggcgct cgccgtggac gtggtcaccg gcgagggccg cacgtggcag
     8521 cccgggccgg ccctcaccca gtccttcgga ttcggcggcc acaacggcgt ccttgtcctc
     8581 ggccccgccg gataggttcg gagcgaagcg atggcagcag agcgaaagag cgatccgcac
     8641 gacgtgttcg cgtggatcga cgacagcacc cggcgccggg accgggcggg tctcacccgc
     8701 cggatccagg tccgcggccc ccggccgaac gtgatcgact tcggcggcaa cgactacctc
     8761 ggcctcaccc gccaccccga cgtggtccgg gcggtggccg acgcgtcact gacctggggc
     8821 gcggggtcga ccgggtcccg gctggcgacc ggaaccaccg aggtccacgc cgaactggag
     8881 cgtgagctcg ccgagttcag cggagcggag gccgcactgg tcttctcctc cggctacctg
     8941 gccaacctcg gcgcggtgac cgtactggcc cgccccggca cgctcatcgc ctccgacgcg
     9001 ttcaaccacg cctccctgat cgacggctac cggctgtcgg gcgcggacgt ggccgacgtc
     9061 gagcacgccg atccgcaggc gctggagcgg gtgctcgccg cgcgggaaca gcagcgcgcg
     9121 gtggcggtga ccgagtcggt cttctcggtc gacggcgacc tggtggacct cggggccgtc
     9181 ctcgaggtct gccggcggca cggcgcgggc ctgctcgtcg acgacgccca cgggttcggc
     9241 gtcatcggcg cgaagggaga gggcgcggtg gccgccgccg ggctggccgg ccaccccgac
     9301 gtggtcacca ccatcaccct gtccaagtcc ctgggagccc agggcggcgc ggtgatcggc
     9361 ccccgccgag tgatcgacca cgtcatgaac atggcgcgga gtttcctgtt cgacaccggg
     9421 ctcgcccccg cctccgccgc cggagccctg gcggcgctgc gggtcctgcg cgccgagccg
     9481 gaccgaccgg cccggacccg cgccgtggcg gtcgccctcg ccgaacgcct ggcggccgcc
     9541 ggactgccgg tgaccgaggc gcaggccgcg gtggtctccg tacgcgggcc ctccgcggcg
     9601 cagaccgcgc agtgggcgca ggactgcctg gacgacggcc tcaaggtggc gtgcttccgc
     9661 ccgccgtcgg tgcccgaccg gttctcccgt atccggctca cctcccgcgc cgacctgacc
     9721 gaggccgaga tcgaccgggc gatcgacgtg gtggtcaagc acagcccctg gtgaagcagt
     9781 tgccccggga gtccggggca ccacgaacgg cccgggccga gtgagggaga ccgtcatgac
     9841 gatcgccggt gggttcctgg cgcacaccac gaagtcaccc gaccgggccg ccctcgccgt
     9901 cggcgacgca gccgggcggc ggtggagcta cggcgcgctg cggcgcggcg cgctcgccgt
     9961 cgcccgggcc ctgcgcgccg agttcggccc cgctcccgga cccgcagtac gcgtcgccgt
    10021 gctcctgggc aaccgtgagg agttcccccg gatcttcctg ggagccgccg tcgccggcat
    10081 tccggtgatg gtcctcgacc ccgcgtggag cgccgcggaa ctggccgccg tcctctccga
    10141 cacgcccccg gcccggctgt tctgcgagag cgccgacggg ccgctcgcac gactcctgcc
    10201 cccggacgcc ctcgtggaag tggcgggagg gggcctcgaa gcgtggctgc gcccgcacca
    10261 cgaggagcct cgggagcccg acgccgacgc cgacgcccgc caggagttcg ccgaggtgcc
    10321 gcacggcgca ccgttctacg tcggcttcac ctcggggagc accggccgcc ccaagggggt
    10381 ggtccgctcg caccgctcct ggctgcgcac cttcgaccgc tacaccgccg agttcggcat
    10441 cggcgccggc gacacggtgc tgctgcccgg ctcgctcgcg cattcgcact tcctcttcgg
    10501 gctcgtgcac gggctgcacg tcggtgcgac cgtccgcctg atgccggcct tcgacgcggg
    10561 acgcgcactc gaccacatcg agcgccacgg cgtcacccgg ctctacctcg tgccgaccat
    10621 gttccaggcg ctgctcgaac acgcgcgccg gcaaccgggc cggcggttcc ccgcggtgcg
    10681 ctccctgctg tcggtcggcg cgaaatggtc cccggccagc cgtgcgacgg ccgcggacct
    10741 cttcccgaac gccgacgccg tggagttcta cggctccacg gagctcagcc tcgtctccgt
    10801 gctccacggc gacgacgacg gtccgcgcga gtcggtcggc agaccggtgg ccggtgtgga
    10861 gctctcgctg cgcacgccct cgggcgaggc ggccggtgtg aacgagccgg gccaggtcca
    10921 tgtgcgcagc gacatgctct tcacccggta cctgtccgcc gaccatgtcg aagcacccga
    10981 tgcggacggc tggttcaccg tcggggacat cgggcgcgtc gacgagcgcg gctatctgca
    11041 cctcgtcggc aggaagcagg gaatgctgat cagcggcggg ctcaatgtgt acccggagga
    11101 ggtcaccgcc gccctgctgc gactggagga gatcgccgag gccgcggtcg tcggactgcc
    11161 cgacgagcgc tggggcgatc tggtgtgcgc ggtggtcagg tggcggcgcg gggcccgtct
    11221 cggtctcgcg gagctgcgcg agcgggcctc ggcccacgtg tcgcggcaga agtgcccccg
    11281 gcggctcttc gagacggacg agctgcccca cacctccagc gggaagatcg accacgggcg
    11341 ggtacggagc cttctgctgg acggccgcca cagcatgcgg gaggtgcggt gaagcgcacc
    11401 ggccgatggc cgcggcggcc gactccgtac ggcttctcag ccccgctcca ccagtacctg
    11461 caacggggcg cggaacgaga gcagggccag catccgcggc gaggtcccgt ccgagagccg
    11521 caggtccggc aggcgggcgg ccgtcatccg catcaccaca tcggcctcca tccgggccag
    11581 ttcggcaccg gaacagcggt gccgcccgat gccgaacgac aggtgcttgc gcacattgga
    11641 ccggtacggg cagagctgtt cgggcttctc gaagacctcg gtgtccgagc cggtggacga
    11701 cagcatcagc agcagcggcg ctccggccgg gagctccaca ccggacaggg tcatcggccg
    11761 gccggtgacc ctgcgccagg tggtgatcgg cggatcccgg cgcagcacct cctcggtcca
    11821 gggcgccacg gtcgccggct cggcggcgaa ctgctgccac agaccgggct cccgcagtgc
    11881 cctgcggtac atggtgctca gcatctgggt ggtcgtcatc tgaccggcga tgatcatgaa
    11941 gtagaccacc gccgccttct gggtcacgcc cagcggttcc ccgtccggca accggtgctc
    12001 ggcgagcgcg ccgagcagcg tgccggcctc gggcgccggc tgcgagacga ggtcggtgag
    12061 ccaggagtag aaggcggcgg cctcgcgggc cagcgccacc tcccgctcgc cccgcggccg
    12121 cccccagaac agttccaggg aggcgtcgct ccagcgggcc agggtgtcga tgtccacgtc
    12181 gatggccgat tccagaccga gcagccgcag catcacccgg aagggaacgt cccgggcgat
    12241 ggtcgtcgcc aggtcgcacg tgccgtcggc ggccagccgc ccttcgacgt cgtcgagcgc
    12301 ctccgccacg accttctcga ccatcggcat cgaggcgttc acggcctggg cgttgaacag
    12361 cttggtcatg atgcgccgat agccggcgtg gctgtccgag ctgttgtttg caagtgtttg
    12421 cgggaggtcg aacctgactc tcgcgaggac gcgaagcgtc tgtaccgaga atcgcccgat
    12481 cgcgtcgatc gcattgtccg gaaggaagtt ctccgggtcg agcagaatgg accgcacgtc
    12541 ctcgtatcgg ctgatcagcc aaagtcccgt gttctcgtcg aacttcacgg gttcgttttc
    12601 ccggagtgcc gccatcgccg gatatgggtc gagcgcatat ccctggtcga aaagatccac
    12661 actgtcaacg ggcattgcca acatcacgtc aattccacct tcccccgttc gaaggtatca
    12721 agccttggtg atcgcgctga ataccggccg gggaagaatc tgtgtgagcc gcgtctcgcg
    12781 cggacgccgc cctggggcgg ggccgcggac ggcgggccgt ccgaagtcag gtctgcggac
    12841 ggcccgcacg tgagcggtcc ggcgtcccgg cacccgccgg tgcccggacg tgactactgc
    12901 tgaggggcgt cgagcgggtt gccgttgttg atgccggcct tcttcgcggc gtcgatggaa
    12961 gcggcggacg gcttcacctt ggtgaaggtg tcgtggccga ccagggtgga cttccaggcg
    13021 ttggcctcgg tggtgccgga ggtcagcagc cactgggtgt tgatccgggc ctcggtgccg
    13081 ccgacgtact ggccgctcca cgtggtcgcg gagtgggcgt tgcggtagtt attcttccag
    13141 gccaccgtcc agccgagggc ggtgccgctg ccgtcggtgg ccggggtgct gtcgtaacga
    13201 ccggtcagga cgtagcggct ctcggcgttg ccgacggccg actcgtaggt gccggtgagg
    13261 gcgccgtcgg cgcccgcggt cacgatgaag gtcgagccga gctggttgta ccaggtgccg
    13321 gtgatgcccg cctcggcggc ggagacctgg gccttcgagt ccttggaggg gtcggccgaa
    13381 gcgctggccg taatcgagat cgtggtcagg gaaacggcga tggcggcgac gacgatcttg
    13441 cgcatgtgag acacgaaaaa atactcccct agttgttgcc cggcgaggga cggaaggcgc
    13501 gcatgtggcg cgcgcccgcc gtatcccgcc cgtcaaggtt tgtgacctcg gccgtgcacc
    13561 tggcggtgtc ggtgaacaaa cagcagtgcg gcatgtgtct ttggcggcag aactggatgg
    13621 tcgaggtccg ggtcgatggt tgccaagggc acatgttcgg tgtaaatcgt actagccttc
    13681 acagggttct caacaacatt ttctgcaaag caatttcggc caaagaatgg ccgagtcctg
    13741 tcggtgactt cgtcaactcg gcccggccgg ggtatccctc acagccaggg gatctgctcg
    13801 gccgcgtacc ggtgggcgcg gaagaccgag ttctgggcgc cggccgagga ctccaggccc
    13861 acgccctcgc cgaaggaccg gaactgcggg accacgaact cccacacgac gtccccgtcc
    13921 ggcgtcacct cgaagagccg gccgaaggag ccctccgcca cgaaggtgtt cccgttgggc
    13981 aggcgctgcg cgctggacat gtacgggctg aagaagttct gcggcgggtt gtcctcgtac
    14041 gaccacacct ccgtgccggt gtgcgggtcg agctccagca cccgcgagta cggcaccgag
    14101 gtggtgtcgc ggtaggttcc gttgtcgaag accagcaggg tgccgccggg cagttcgtgc
    14161 gggtggtgct gctgggccag cacgtccggg ccgatgcgcc actgcacgga cccgtcggcg
    14221 cggtcgaccg acacggtggt ggacgcgctg cggaagccca ccacgatcga gccgtcggcg
    14281 ctctcgttga cggtgttggc catcggccag tggttgcggg cgaagtgccg gttcagcggc
    14341 acctcctccg ggtccaggtg ctcgatggcg gcccagcgcc acacgatctc cccctcccag
    14401 gtcagctcgt acaccacgtc cccgtagatc accccaccgg gcgcctcgga cccggggatg
    14461 ccacccctga tccgggccgc gtcggccggg tccagtggct cgaccgcccc gatgatcagg
    14521 ttgccgttgc gcaggatcga ggcgtcgtgg tggtggaagg ggtgccggac ctcgcggagc
    14581 accgtggagt cgggcgccag ctcctggaag atgccgccgt ggtagacgtc ccagatgggg
    14641 aacagggtcg ggccggtggt gtccttggcc gcgtagaaga ggttgccgcc cggcaggagc
    14701 tgcgcctggc ggccgggcgg gtgcggggag ttccaggtgt gcgccggccg gccctcgatg
    14761 tcgacgaggt ggatctcgcc ggcgctggtg atcggcgtgt agagggtgag gccgccgtag
    14821 ctgcgctcgg ggtcgtgggc gatcaggccg acgccgcggc ggcgcacggt gttctggtcg
    14881 acggtcatga acatctcctg ggagtggtgg ggcgggtggg gcgggacggg gtggcgtggc
    14941 tcagcggacg gtgacggcgg ccgggtcggc ggccgtcagg ggtccggggt tcaggtaccg
    15001 cagcagcgcg gcgcggtcgg cggcgccggg cagtttctgg gcggccttgg cccaggccgc
    15061 ctcctcctcc aactgcgcca gcagttcggg ggagagggtg gcgccgtagg tgtagcgcgg
    15121 ctggtaggcg tcgacgtagg cggcctggag ggcgcccttg gactgcgtca gtacggcctt
    15181 gcgggcacgg gccgggtcgg cgcccagttc gcgctgggcg cgcagcagcg tgcgcaggac
    15241 cgcggtggtg ctctcctcgt tcgcggaggg gccggcgacg aggagggtcc tggccgtgta
    15301 cccggtgaag ggcagctcgg cgtaggagcc gccgagggcg gtgcgcgcgg cgtcgtagaa
    15361 gctggggaag gtgaccccgg cgtcgatgtc cccccgggcc agcgccgaag tgacctggtt
    15421 cggggcgagg ttgaccacgg tcacgtccgc cgccgtcagc tgcgccgagg cgagcatgcg
    15481 cgacagggcg tactcgacgt tcgtgccctg cggaaccccc accttgcggc ccttgagcgc
    15541 ggcgaagccg gtgatctgcc ggtcggtccg ggtcaggagg cgccagtcgg agaaccggga
    15601 caggtcggcg acgacccgca gctcgcgccc gcccagggcg gccgtcacgg cgggcaggtc
    15661 gcccacgacg ccgagctggg cctggccgcc gagcacggcg ttcagggcgt cccggccggt
    15721 gggctgggtc gtgacggtgg cgcgtacgcc ctcggcggcc cagagatcgc cgtcctcggc
    15781 cacgtggacg ggggcgccgc cgaggtagtc gctcgcggcg agcgtgacgg ccgggcggtc
    15841 gccggcggcc gtaccggacg gggagccggc gcaggccgtg gcgagcgggg agagcagggc
    15901 ggcgagcagt acggcggcca ccgcgcgggg tccgggcatg gtgaacggtc ctttcctgga
    15961 caggggtgtg gtcgtgggtg cggtcgtggg acgggacggt ggggcgtggt gctgggcgcg
    16021 gtggtgggcg cggtggtggg cagcggttca ttcggagccg aggtggcggg cgatcaggga
    16081 ccgcaggtcg ggatcgggtg ctccggcggg caccgcgtgg tcggcgagca cccgcccggg
    16141 actcccgccg aggacgatca cgcgcccggc cagcgccagt gcctcgtcga tgtcgtgcgt
    16201 gacgaacagg acggtggtgc cgcggcgctg ccacagctcc cgcagcaggc tctgcatccg
    16261 ggtccgggtc agcgcgtcca gtgccccgaa cggctcgtcc atcaacagca cttcgggttc
    16321 ggcggccagc gcccgggcca gcgccacccg ctgctgcatc ccgcccgaca gctgggccgg
    16381 atacttctgc gcgccgtccg cgagccccac ctcggccagc gccgcgaggg cgcgcctgcg
    16441 gcgctccgca cgcggcagac cgagccgctt gagggcgaac tcgacgttgc cgcgggccgt
    16501 gcgccacggg aacagcgcgt agtgctggaa gaccacgccc cgctcggggc ccggcccgcg
    16561 caccggctcg gaccccgccg tcacccgccc cgcggtgggc cggacgaatc ccgccaccag
    16621 gttgaggacc gtggacttgc cgcacccgct gggcccgagc agcgccgtga aggagcccgc
    16681 cgggaactcc aggtcggtgc gctccaggac cggggcggcg ctcccgtacc ccgcggacag
    16741 cccctccagc cgtacttcga ggctcat
//
