LOCUS       reptomyces_RBGC_345159 16237 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_345159
VERSION     Streptomyces_RBGC_345159
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000424825.1
  ORGANISM  GCF_000424825.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..948)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928146"
                     /pseudo=False
                     /translation="MVLYSIRKLTGAIAVLLALSALVFMAGRALAPGDPAQLIAGPKAS
                     PETVENIRQSLGFDRPLVTQYLDWLGSALRGDLGTSPFSGQANRDVIAQQAPVSFQLAL
                     FGLLVAVAIGIPAGVYAATRAKQARVWAVRLPLLIAFAFPAFVSGSFALYVATHYLPNL
                     YSPNYIPVSDGLLANAQMMLLPVLAVGIPTAPLIMQMTRSAMLEVLATPYISTARTNGI
                     AEWRVTYVYALRAAMPPVLTLIGMIFGLLVGGLFIVEQIFSLPGLGRGILDSLELRDFS
                     QATGQALVLATAFILGNLLVDLMLPLVDRRITRS*"
     CDS             complement(959..1968)
                     /protein_domains="PF00005"
                     /protein_domains="PF08352"
                     /protein_domains="TIGR01727"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928147"
                     /pseudo=False
                     /translation="MTSTTTAEATRLVLRAEDVRKYFKVRRAKLRGPRAYVHAVDSVSL
                     TLDAGRTLGIVGESGCGKSTLGRVIVGLEAPDAGTVHVGGDATAAGTPGARGVVQAVFQ
                     DPASALDPRMTVRQSIAEALPGVDRAARDRRVAEVLEEVGLAEEYAGRYPHELSGGQQQ
                     RVCIARAIVGDPELILLDEAVTSLDASLQAQVLGLLERLQERTGVAYVFISHDLRAVRR
                     FSDQVAVMYLGQLVELAPARDFDTGLLHPYSVALRSTEPRLPDDTGERTPRIVLEGEPP
                     SAVDPPPGCRFAARCPVVEPRCRTELPALVEERPGHLVRCVKPGALTPAVPVEGE*"
     CDS             complement(1966..2822)
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928148"
                     /pseudo=False
                     /translation="MTTAHPAPDMSPGGAGLSVRDLTISYQRDGRLHVAADKVSFDLPA
                     GGRLGLVGESGSGKSTLASAVLRTLPDNATVSAGEISFGGSDLLGLDADGLRTIRSTRI
                     ARVPQDPLASLNPVFTIGRQLTDVVRAHHRTSKAEAIGIAEEVLRQVGLPDVEVKRRSF
                     PHELSGGMRQRVIIAMALINRPQLLIADEPTTALDVTVQAQIVELLRERVTAAHMSLLL
                     ITHDIGVVSELCTQVAVMYRGRIVEQGPAEDVLTNPQHTYTASLLAAARGDATEHRTQP
                     GEAA*"
     CDS             complement(2820..4348)
                     /protein_domains="PF00496"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928149"
                     /pseudo=False
                     /translation="MPPARRRGTAAVVLCLAAALVFSACSAPVAKSARPDGLVVAETTP
                     PSTLDPQGSSMFADRFAWQLSYECLYTTTADGRVEPALATGYEKSADGLKYTFTLREDV
                     RFHNGAEMTADDVVFSFDRLSNSPDGIDKEVFPMLDKVEKAAADKVTFTLKKPDAGFVN
                     NMANPLVWGCAIMSEKAADEANPAITMVGTGPWKQTEYRANSKLQLERNGGYWGKKAAA
                     PALSVLYIPNVATQVANLQADKIDLMFPDSASADAVRDDPDVTLREAKTDSTLFLQVNN
                     LRKPFDNQLVRQALALAIDRQELADGAYQGDARPSGYVPSAEWAPEVKDLPFYQPDIPR
                     AKKLLREAGFPRGFSTTLMYISGYDPGTDNMMALLQDQLARVGIKVKLLPKEQAAWSAK
                     LGGPDYALSWNAQSYYPNPLQYVLPAEGRQGPTPKSLQKLIDEARSAGSQSAYYDKLTE
                     ISRHEATLVYPTVTLLASNMFAAYRDTLAKVSVPPSQSRAFLAGVTKEQRR*"
     CDS             4703..5493
                     /protein_domains="PF01614"
                     /protein_domains="PF09339"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928150"
                     /pseudo=False
                     /translation="LTDQLAPTPGARNNSASVRRALGILLRLGDECEGRGYTLSQLAAH
                     LDLSKPTTLRLIQPLVEAHLVQTLPGGTYRLGWRNAQLGQAYLAGADPHRDMHDVLERL
                     SEATRETVHLVTQDFPHVVYVDKVDSPLAVRMASRIGSTQPAYCTSVGKAMLAHAEEAM
                     VDVVIAAGMPARLENTLTEGGALRAELAQIRARGWAIDDVENEAGVRCVAAPIFDATGA
                     VTSAISVSAPVERMSLEHAGEVASLVRAAARECSQRWGGHG*"
     CDS             complement(5742..7846)
                     /protein_domains="PF00069"
                     /protein_domains="PF13360"
                     /protein_domains="PF13360"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928151"
                     /pseudo=False
                     /translation="MNPLGYGDPLRLGPYRLIGVLGEGGMGKVYLGRDGSGRTAAVKVL
                     HPELAQDAQMSQRFVREAEAAQAVRSKGVARVLSVETESGRPFIAAEFLAGPTLDEAVL
                     HYGALQEPYVRALGAALAGTLGDIHAAGLVHRDLKPSNIVLTAAGPRVIDFGIARPEHG
                     LTLTTTGQTPVTPGYGAPEQVLGQRTGPPGDVFALGTVLVYASTGSPAYSGGHAAAVQY
                     EVVHGQPRLDALPPALRQLIEPCLAKDPAQRPLPAQVASAMAAPRGAHKLWKEGPVAEE
                     IGRSEARVRELAAFPEVETGTATTLSGAAPRGGGPSRRRVLTGVAAGVTVLAAAGGAGA
                     WWLRREETPPRAHPWDADPLAEGDYEKGKAPDPLWGPKKVSASGGRLLVVRDTVILDSQ
                     SPDLIAYDVATGKRKWMVKGVGWPAVYVPKLDLILASSLDTLHGISPRTGKQLWKHDVG
                     IVGKLAVAGDVYYYDDLSSNWSTGDPGKVVALRLRKRGAPEELWQKRMPFDFEADDIEA
                     AAGGGRLVLAAGEYGVVALDTEDGGKVWKVPAKSGSAWTPYITGDSVCLGGESLRSFRL
                     SDGDPGWSVPASTNAGLFVGTADEDHLYLVADSQLRCHSVKDGSKKWTRELANAIAGMP
                     VLSGDTVWVSSSQQAEGVRAFRKDTGEPLWTRHEKGRPGQGGWALAGAGNRMFTWRDGR
                     LTAMPVV*"
     CDS             complement(7939..10400)
                     /protein_domains="PF00069"
                     /protein_domains="PF13360"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928152"
                     /pseudo=False
                     /translation="MPSSPAPRTPLALPLAYDDPHQLGPYRLIARLGSGGMGTVYLGRD
                     AGGRTVALKTTHARLAASPEFRIRFRLETDAARVLGGRHGAEVVDADPLAPTPWLATEY
                     VLGPALDAAVEQCGPLPEAAVRALGAALCEALGQLHSSDVVHRDLKPSNILLSASGPKV
                     IDLGIARAIGDERLTRTGAAAGTPAYMSPEQATGGEHTAAGDVFALAGVLVFALTGRGP
                     FGGGQAADLLYRVRYGEPDLAGVPDALRPALERALRKEPHHRPGTAELAAQLSGGPGDP
                     RDPRGPHGPGGAEFADHLPAALLARIAWHAGAVWQIAPQRAAPPAGVYDAGAHGSGAYG
                     SGAAPGGAGGPTGAPREPGRPSRRRVLTWAGGSVFGASAVAGGAWAWSGRGGSAGASGP
                     AASPSRGAGGGPRPVWQAPTLNTQDEYDLPPIAAGGLLLSMDKKGLVAFDAKGGERRWG
                     NPDLHAQQLSTDGQTIHVLLPEPAGRKGGKRKGGGAGVAVCTLDPGSGSVGETLGTLPD
                     FDGRPKREGGFGAPTVQPLRTSGHVLYLAARTREANASSQEITKGWYVLAFDLRAGREL
                     WRAPLADYEYGSTHAQTSGYLAARSGDRLLLTRVADGEDRDDLSRYVTLARDTRTGRKL
                     WEGTRLPLGATRDGAASLAPIPTDRRHLYLSSRQLAAFRLSDGKRAWAFSSARADRVEE
                     DEQGHLVALYGPPSVRDGVVYATERGQGLIAVDAADGRLLWREERRPGHRPSVGFVPLV
                     GERYVYTLVVDKRERTYLSAVDRETHRSDWTFTMGGLDGAGTSLVLDEGSGRIVGSTLL
                     GTYAIPLE*"
     CDS             complement(10447..11405)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928153"
                     /pseudo=False
                     /translation="MEPLRQDDPRHPGRYRPVGGIDAADTGVPVPVRRLVARMPGGDHT
                     LLLTLPRPELAGDGAYGQRFVAEAEQARRLGGFAPALEQLVEVFAGAPGEPPWHASPYA
                     PAVPLPGALAAHGRGLGERTVRALGLELAGTLAALHVQGVAHAGVAPGTVLLGADGPRL
                     TGFGSVRALAPEGRDRRAVAGLPPEALPPEQLSGGRPRPPGDVYGLGAVLAYAATGRLA
                     PDVSGLPMGLRETVGSCLAADPADRPQASAVRDALRAGLAAPVPPGPPAGPAPPVPAPV
                     TTLDGGADAFGPGWLPGRVIAALARQSARALAAPGDRR*"
     CDS             complement(11440..11600)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MGPRPASGNGKGSRDEASAASAGVSPGPTGSGDAPGTAQPPRGAD
                     DAPSESLV"
     CDS             complement(11775..12802)
                     /protein_domains="PF13377"
                     /protein_domains="PF00356"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928154"
                     /pseudo=False
                     /translation="VTRDDVARLAGTSTAVVSYVINNGPRPVAPATKERVLAAIAELGY
                     RPDRVAQAMASRRTDLIGLVVPDARQPFFAEMAHAVEQAAADRGKMVLVGNSDYLDERE
                     VHYLRAFLGMRVSGLILISQGPSEHAATEIEAWDARVVLLHRRPEAIDDVAVVLDDVGG
                     AQLATRHLLEHGHSDVACLGGMESTPANGDPVTDHIDGWTRAMQEAGRSVEGRLFKAPY
                     NRYDTYRLALDLLRRPDRPTALFCSTDDQAIGVLRAARELGIDVPGELAVTGFDNVKEA
                     ALTDPPLTTVGSDREAMARAAVDLVLDDGLRVAGSRRERIRQFPSGLIVRRSCGCETAA
                     PA*"
     CDS             complement(12823..13661)
                     /protein_domains="PF00486"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928155"
                     /pseudo=False
                     /translation="MSSLLLLTNALQPSSEVLPALGLLLHQVRVSPAEGPALVSTPGAD
                     VILVDGRRDLPQVRSLCQLLRSTGPGCPLLLVVTEGGLAAVTAEWGVDDVLLDTAGPAE
                     VEARLRLAMGRQQTGADSAPTEIRNGDLSVDEATYSAKLKGRVLDLTFKEFELLKYLAQ
                     HPGRVFTRAQLLQEVWGYDYFGGTRTVDVHVRRLRAKLGPEHESLIGTVRNVGYRFVAS
                     EKGKGGKRDREAREAADLKTRADARAVAEAAEEVARNAAGGVNQAGTRPGEGVNRRA*"
     CDS             13819..14744
                     /protein_domains="PF12697"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928156"
                     /pseudo=False
                     /translation="MRSRIAHMGSAAQCETGRIRVRESPRERLRGVLRTDDGVRIEAAY
                     ERYAGPGDGTAIVLAHGFTGSLERPALRRAARVLTAHGAVVTFSFRGHGGSGGRSTVGD
                     REVLDLAAATRWARALGHRRVATVGFSMGGSVALRHAGLRHAGPGGAGLEDTGLEDAGP
                     GDAGPGDTAHPDAVVAVSAAARWYYRGTAPMRRLHWAIERPAGRLVSRWGLGTRIHSQE
                     WDPVPLPPVDAAAMITPLPLLIVHGDRDPYFPLDHPRSLADAADPDRTRLWVEPGFGHA
                     ENAAPAELLHRVGAWAAQAAATGAVPG*"
     CDS             14896..15161
                     /protein_domains="PF02597"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928157"
                     /pseudo=False
                     /translation="MASGTIRYWAAARSAAGTAEEAYQAGTLAEALDAARERHAGSPEF
                     ARVLARCSFLVDGNPAGTRARDTVTLSEGGTVEVLPPFAGGAR*"
     CDS             15159..16237
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2928158"
                     /pseudo=False
                     /translation="VTGRYGDGYGAPQPYEPAGGAWDGPQGPPPADPYGYAQQGQPQQP
                     HQHQPHHHQPHQPRPVRPQPGTATGPAPLPPQPAAPQPATPQPPPHQPADEPRPEAAPR
                     AARTGRAGRARPSPLIAPGLQPAVLTVALAALLAGTSSLPRPVFAVAVVLLQAVTAAGW
                     YRLNGMWPARQGIALAFLAGVATDVALLTTSRAHTATAVVGTLGIWCVLVIVLQLRSHA
                     SPDERLYALTAGLTATALTVLAAGYLAIARTVEEAVIAGAAAVALATLVRALPLPPFVS
                     PVLAVLAGGGAGALAGRYTDLGTTDGSLLGLAAAVCAVTGLRVASYDYPSRFVHMTAGV
                     VLPLTLAAPAVYFLGRALG*"
ORIGIN
        1 ttaggaacga gtgattcggc ggtcgacgag cgggagcatc aggtccacga gcaggttgcc
       61 caggatgaac gcggtggcga gcaccagggc ctggccggtg gcctggctga agtcgcggag
      121 ttcgagggag tcgaggatgc cgcggccgag gccgggcagg ctgaagatct gttcgacgat
      181 gaagagtccg ccgaccagca gcccgaagat catgccgatg agggtgagta cggggggcat
      241 ggcggcccgg agcgcgtaca cgtaggtgac gcgccattcg gcgatgccgt tggtgcgcgc
      301 cgtcgagatg tacggcgtgg cgagcacttc cagcatggcg gaccgggtca tctgcatgat
      361 gagcggagcg gtggggatgc ccacagccag gacggggagc agcatcatct gcgcgttggc
      421 gagcagaccg tcactgaccg ggatgtagtt cggcgagtac aggttcggga ggtagtgcgt
      481 ggcgacgtag agcgcgaagg agccggagac gaacgccggg aaggcgaagg cgatcagcag
      541 cggcagccgt accgcccaca cccgtgcctg cttggcgcgg gtggcggcgt acacgccggc
      601 gggtatgccg atggcgacgg cgacgagcag gccgaacagc gccagctgga acgagacggg
      661 tgcctgctgg gcgatgacgt cgcggttggc ctggccggag aagggcgagg tgcccagatc
      721 gccgcgcagg gcgctgccca gccagtccag gtactgggtg acgagcggac ggtcgaaccc
      781 cagggactgc ctgatgttct cgaccgtctc gggggacgct ttcgggcccg cgatcagctg
      841 cgccgggtcg ccgggggcga gggcgcggcc ggccatgaag accagcgcgg agagggccag
      901 gaggaccgcg atcgccccgg tcagcttgcg tatcgagtag agaaccatgg gttcgcctca
      961 ctcaccttcg acggggacgg ccggagtgag ggcaccgggc ttgacgcagc ggacgaggtg
     1021 acctggtctc tcctccacca gcgcgggcaa ctccgtacgg cagcggggct cgaccaccgg
     1081 gcagcgcgcg gcgaaccggc agcctggcgg cggatcgacg gcgctgggcg gctcgccctc
     1141 cagcacgatc cgcggtgtgc gctccccggt gtcgtcgggg aggcggggtt cggtggaccg
     1201 cagggccacc gagtaggggt ggagcagccc ggtgtcgaag tcgcgggccg gtgcgagttc
     1261 gacgagctgc cccaggtaca tcaccgcgac ctggtcgctg aagcggcgca cggcccgcag
     1321 gtcgtgcgag atgaacacgt acgcgacgcc cgtgcgttcc tggaggcgct ccaggaggcc
     1381 gagcacctgc gcctgcaagg aggcgtccag cgaggtgacc gcctcatcca gcaggatcag
     1441 ttccggatcg ccgacgatcg cgcgggcgat gcagacccgc tgctgctggc cgccggacag
     1501 ctcgtggggg tagcggccgg cgtactcctc ggcgaggccg acctcttcga gcacctcggc
     1561 gacgcgccgg tcgcgcgccg cccggtccac gcccgggagc gcctcggcga tgctctgccg
     1621 gacggtcatc cgcgggtcca gcgcgctggc cgggtcctgg aagacggcct ggacgacgcc
     1681 gcgggcgccg ggggtgcccg cagcggtggc gtcgccaccg acgtggaccg tgcccgcgtc
     1741 gggtgcttcg agcccgacga tcacccggcc cagggtggac ttgccgcatc ccgactcgcc
     1801 gacgatgccc agggtccggc ccgcgtcgag cgtcaggctg acggagtcga cggcgtgtac
     1861 gtaggcgcgg ggaccgcgca gcttggcccg gcggaccttg aagtacttgc gtacgtcctc
     1921 ggcccgcagc acgaggcggg tggcctcggc cgtcgtggtg ctggtcatgc ggcctcccct
     1981 ggctgggtgc ggtgctccgt ggcgtcgccg cgtgcggcgg cgagcagcga ggcggtgtag
     2041 gtgtgctgtg ggttggtgag gacgtcctcg gccggtccct gttcgacgat ccggccgcgg
     2101 tacatcaccg ccacctgggt gcacagttcg ctgacgacgc cgatgtcgtg cgtgatgagc
     2161 agcagcgaca tgtgcgcggc ggtgacgcgc tcgcgcagca gctcgacgat ctgggcctgc
     2221 acggtgacgt cgagtgcggt cgtgggctcg tcggctatga gcagctgcgg ccggttgatc
     2281 agcgccatcg cgatgatcac gcgttgccgc atgccgccgg agagttcgtg cgggaagctc
     2341 cggcgcttca cctcgacatc gggcaggccg acctggcgga ggacctcctc ggcgatgccg
     2401 atcgcctcgg ccttggacgt acggtggtgg gcgcgtacga cgtcggtgag ctgcctgccg
     2461 atggtgaaca ccgggttgag gctcgccagg gggtcctgcg gtacccgtgc gatccgggtc
     2521 gagcggatgg tgcgcagccc gtccgcgtcg aggccgagca ggtcgctgcc gccgaaggag
     2581 atctcccccg cggagacggt cgcgttgtcg gggagggtac ggagcaccgc cgacgccagc
     2641 gtcgacttgc cggagccgga ctcgccgacg aggccgaggc gtcctccggc gggcaggtcg
     2701 aagctgacct tgtcggcggc gacgtggagg cggccgtcgc gctggtagct gatggtcagg
     2761 tcgcgcacgg acaggccggc gccaccggga gacatgtcgg gggcggggtg tgcggtcgtc
     2821 atcgccgctg ctccttcgtt acaccggcca ggaaggcgcg gctctggctc ggcggcaccg
     2881 acaccttggc gagcgtgtcg cggtaggcgg cgaacatgtt gctggcgagc agcgtgacgg
     2941 tcgggtagac gagcgtcgcc tcgtgccggg agatctcggt cagcttgtcg tagtaagcgg
     3001 actggctgcc ggcgctccgg gcctcgtcga tcagcttctg caacgacttc ggggtcggcc
     3061 cctgccgccc ctcggcgggc aggacgtact ggagcgggtt ggggtagtag gactgcgcgt
     3121 tccacgacag ggcgtagtcc gggccgccca gcttggcgct ccaggccgcc tgttccttgg
     3181 gcagcagctt gaccttgatc ccgacgcggg cgagctggtc ctggagcagg gccatcatgt
     3241 tgtcggtgcc cgggtcgtat ccgctgatgt acatcagcgt ggtggagaac ccgcgcggga
     3301 atccggcctc gcgcagcagt ttcttggccc gcgggatgtc cggctggtag aagggcaggt
     3361 ccttgacctc cggtgcccat tccgccgacg ggacgtagcc gctgggacgt gcgtctccct
     3421 ggtaggcgcc gtccgccagc tcctggcggt cgatggccag ggcgagtgcc tgccggacga
     3481 gctggttgtc gaacggcttg cgcaggttgt tgacctggag gaagagcgtc gagtcggtct
     3541 tggcctcgcg cagcgtcacg tcggggtcgt cgcgcaccgc gtcggcgctg gccgagtcgg
     3601 ggaacatcag gtcgatcttg tcggcctgga ggttggccac ctgggtggcg acgttgggga
     3661 tgtagagcac cgagagcgcg ggcgcggcgg ccttctttcc ccagtagccc ccgttgcgct
     3721 cgagctggag cttgctgttg gcgcggtact ccgtctgctt ccaggggccg gtcccgacca
     3781 tggtgatcgc cgggttggcc tcgtcggcgg ccttctcgct catgatcgcg cagccccaca
     3841 ccagagggtt ggccatgttg ttgacgaagc ccgcgtccgg cttcttgagg gtgaaggtga
     3901 ccttgtcggc ggcggccttc tccaccttgt ccagcatcgg gaagacctcc ttgtcgatgc
     3961 cgtccgggct gttgctcagc cggtcgaagg agaagacgac gtcgtccgcg gtcatctcgg
     4021 cgccgttgtg gaagcggacg tcctcgcgca gcgtgaaggt gtacttcagg ccgtccgcgg
     4081 acttctcgta gccggtggcc agggcgggct cgacccggcc gtcggcggtc gtggtgtaga
     4141 ggcactcata ggagagctgc caggcgaatc ggtccgcgaa catgctggaa ccctgcgggt
     4201 ccagcgtgct cgggggtgtg gtctcggcca ccaccaggcc gtccggccgc gcgctcttgg
     4261 ccacgggggc ggagcaggcc gagaagacaa gggcggccgc gaggcagaga acaaccgcgg
     4321 cggtgccacg tcggcgcgct gggggcatac ggtcctcact tcgccggcgc tcagggagcg
     4381 cagttcacga gcacggattg tgcagtggat tgtgcagtgg gttttgcaat gcaacacatc
     4441 gctttgcatt gcatggcggt gactataatg cctacggcat atgacacaag gggctgggca
     4501 gaaccgggag gatgctgtga tgaggaagca cccggtcctc ccccggctcc gcgcggatcg
     4561 caccacactg gccggtgcgt cgccccgtgc cccccgaagc ctccagcgac gaccaggcgg
     4621 cgcacagcgg agagcgagtg ctccgcgaca gccgcccggg ttacaccacg gccgacaccc
     4681 cactcgacga ggagacctgt cttgaccgac cagctggcac ccacccccgg cgcacgcaac
     4741 aactccgcct ccgtacgccg ggcgttgggg atactcctca gactcggcga cgaatgcgag
     4801 ggccgcggat acaccctcag ccaactcgcc gcgcacctgg acctgagcaa gcccacgacg
     4861 ctgcggctga tccagccgct cgtcgaggcc cacctcgtcc agacgctgcc cggcggcacc
     4921 taccggctcg gctggcgcaa cgcccagctg ggccaggcgt acctcgccgg ggccgacccg
     4981 caccgggaca tgcacgacgt actggagcgc ctctcggaag cgacccggga gaccgtgcac
     5041 ctggtcaccc aggacttccc gcacgtggtc tacgtcgaca aggtcgacag cccgctcgcg
     5101 gtacgcatgg cgtcacgcat cggcagcacg cagccggcgt actgcaccag cgtcggcaag
     5161 gccatgctgg cgcacgccga ggaggccatg gtcgacgtgg tgatcgcggc cgggatgccc
     5221 gcccggctgg agaacaccct caccgaaggc ggcgcgctgc gcgccgagtt ggcgcagatc
     5281 cgggcccggg gctgggccat cgacgacgtg gagaacgagg cgggggtgcg ctgcgtggcg
     5341 gcgccgatct tcgacgcgac gggagccgtg acgagcgcga tcagcgtctc ggcacccgtg
     5401 gagcgcatgt cgctggagca cgccggggaa gtggcgtcac tggtacgcgc cgccgcccgg
     5461 gagtgctcgc agcggtgggg cggacacggc tgaacggcac cgcgtgtgcg cgcggcgggc
     5521 gcgcggacgg gcccgtgcct ggcgggaggc ggcccgacag ccgccccgcc aggcgcgcgc
     5581 ggccggacga ccggcgccgc cgaaagcctc ccaccgcacc tgccccgggc agacgcgcgc
     5641 ggccggccag cgcaccactg agcagacgcg ccgccgggca cacaccctgc caggcgggca
     5701 ggcgcggcca ggcatacgcg ccgccagcgc aagcgcgcgg tcagacgacc ggcatcgccg
     5761 tgagtctccc gtcgcgccac gtgaacatgc ggtttcccgc gcccgccagg gcccaaccgc
     5821 cttgcccggg ccgtcccttc tcgtggcggg tccacagcgg ttccccggtg tccttgcgga
     5881 aggcccgcac cccctccgcc tgctgcgagg acgagaccca gaccgtgtcg cccgagagga
     5941 cgggcatccc ggcgatggcg ttcgccagct cgcgcgtcca cttcttggag ccgtccttga
     6001 cgctgtggca gcgcagttgg ctgtcggcga cgaggtagag gtggtcctcg tcggcggtcc
     6061 ccacgaacag ccccgcgttg gtcgacgcgg gcaccgacca gccggggtca ccgtcgctga
     6121 gccggaagga gcgcagcgac tcgccgccca ggcagacgga gtcgccggtg atgtacgggg
     6181 tccacgcgct gccggacttc gccgggacct tccacacctt gccgccgtcc tccgtgtcca
     6241 gcgcgacgac cccgtactcc cctgcggcga gcaccagccg gccgccgccc gcggcggctt
     6301 cgatgtcgtc ggcttcgaag tcgaacggca tccgcttctg ccacagttct tccggcgctc
     6361 cgcgcttcct gaggcggagg gccaccacct tgccggggtc gccggtggac cagttgctgg
     6421 agaggtcgtc gtagtagtac acgtcgccgg ccacggcgag tttgcccacg atgcccacat
     6481 cgtgcttcca gagctgtttg ccggtgcggg gcgagatgcc gtggagcgtg tccaggctgg
     6541 aggcgaggat gaggtcgagc ttcggtacgt agaccgccgg ccagccgacg cccttcacca
     6601 tccacttgcg cttccccgtg gcgacgtcgt aggcgatgag gtccggggac tggctgtcga
     6661 ggatgaccgt gtcccggacg acgagcaggc ggcccccgct cgccgacacc ttcttggggc
     6721 cccacagcgg gtcgggcgcc ttgcccttct cgtagtcgcc ctcggcgagc gggtccgcgt
     6781 cccagggatg ggcgcgcggc ggagtctcct cgcgccgcaa ccaccaggcg cccgcgccac
     6841 ccgccgccgc gagcacggtc acccccgcgg ccaccccggt gagcacgcgc ctgcgggacg
     6901 ggccgccgcc gcgcggggcg gcgccgctga gcgtcgtggc ggtacccgtc tccacctcgg
     6961 ggaaggccgc caactcccgc acccgcgcct cggaccggcc gatctcctcg gccaccgggc
     7021 cctccttcca cagcttgtgc gcgccgcgcg gtgccgccat ggccgaggcg acctgggcgg
     7081 ggagggggcg ctgcgcgggg tccttggcca ggcacggttc gatcagctgc cgcagcgcgg
     7141 gcggcagcgc gtccagccgg ggctgcccgt gcaccacctc gtactgcacg gccgccgcgt
     7201 gaccgcccga gtaggcgggc gagccggtcg aagcgtagac gaggaccgtg cccagcgcga
     7261 agacgtcgcc gggcggcccg gtgcgctgcc cgagcacctg ctcgggcgcg ccgtagcccg
     7321 gcgtgacggg ggtctgtccg gtggtggtca gggtcagccc gtgctcgggg cgtgcgatgc
     7381 cgaagtcgat gacgcgcggt ccggccgcag tcagcacgat gttggacggc ttgagatcgc
     7441 ggtgcaccag gcccgccgcg tggatgtcgc cgagcgtgcc ggcgagcgcc gcacccagcg
     7501 cccgcacgta gggctcctgg agcgcgccgt agtgcagcac cgcctcgtcg agcgtcggac
     7561 cggccaggaa ctccgccgcg atgaaaggcc tgccgctctc ggtctccacg gacagcacgc
     7621 gcgccacgcc cttgctccgc acggcctgcg ccgcctccgc ctcccgcacg aagcgctgcg
     7681 acatctgcgc gtcctgggcg agttcggggt ggagcacctt gacggcggcc gtacggccgg
     7741 agccgtcgcg tccgaggtag accttcccca tcccgccctc gccgagcacg ccgatgaggc
     7801 ggtaggggcc gagccgcagg gggtcgccgt agccgagggg gttcatctgg tccttcttct
     7861 cctgccgttg ctttcgccgg acgctgtcca ggcgctgtcc ggacgccgtc cgggggcggt
     7921 gcctggtggc gcgccggtca ctccagggga atggcgtacg tgcccagcag cgtggagccg
     7981 acgatccggc ccgacccctc gtccaggacg aggctcgtac ccgctccgtc caggccgccc
     8041 atcgtgaacg tccagtcgga gcggtgggtt tcgcggtcga ccgcgctgag gtacgtgcgc
     8101 tcccgcttgt cgaccaccag ggtgtagacg tagcgctccc cgacgagcgg cacgaagccg
     8161 accgagggcc ggtgtccggg gcggcgctcc tcccgccaca gcagccgccc gtcagcggcg
     8221 tcgacggcga tcaggccctg gccacgctcg gtcgcgtaca ccacgccgtc ccgcacggac
     8281 ggcggaccgt agagtgccac gaggtgcccc tgctcgtcct cctccacccg gtcggcccgt
     8341 gcgctggaga acgcccacgc cctcttcccg tccgagaggc ggaacgcggc gagctgccgg
     8401 gaactcaggt agaggtgcct gcggtcggtg gggatcggcg cgagcgaggc ggcgccgtcg
     8461 cgggtggcgc cgagcggcag gcgggtgccc tcccacagct tccggcccgt acgggtgtcc
     8521 cgcgccagcg tcacgtagcg gctgaggtcg tcccggtcct cgccgtcggc cacccgggtg
     8581 agcagcagcc ggtcgccgct gcgggcggcc aggtagccgc tggtctgggc gtgcgtggag
     8641 ccgtactcgt agtccgcgag cggtgcgcgc cacagctccc ggcccgcgcg caggtcgaag
     8701 gcaaggacgt accagccctt ggtgatctcc tgggaggagg cgttcgcctc gcgggtccgc
     8761 gccgccaggt agagcacgtg cccgctcgtg cggagcggct ggacggtggg cgcgccgaag
     8821 ccgccctcgc gcttcggcct gccgtcgaag tcggggaggg tgccgagggt ttcccccacg
     8881 gagcccgaac cggggtccag cgtgcagacg gccacccccg cgccaccgcc cttccgcttg
     8941 ccccctttcc gccctgcggg ctcgggaagg agtacgtgaa tcgtctgtcc gtcggtgctg
     9001 agctgctgcg cgtggaggtc cgggttgccc cagcgccgct ccccgccctt ggcatcgaac
     9061 gccaccaggc ccttcttgtc catgctcagc agcagaccgc ccgccgcgat cggcggcagg
     9121 tcgtactcgt cctgggtgtt cagggtcggc gcctgccaca cgggccgcgg ccccccgccc
     9181 gccccgcgcg agggcgaggc cgccggtccg gacgcacctg cggagccgcc cctgccggac
     9241 cacgcccagg cgcccccggc cacggcggag gccccgaaca cggaaccgcc cgcccacgtc
     9301 agcacccggc gccgcgaggg ccgccccggc tcccgcggcg cccccgtcgg tccgcccgca
     9361 ccgcccgggg ccgcgcctga gccgtacgcg cctgagccgt gtgcgcccgc gtcgtacacg
     9421 cccgccggcg gggccgcgcg ctgcggggcg atctgccaga cggcaccggc gtgccaggcg
     9481 atccgggcca gcagggcggc cgggaggtgg tcggcgaact cggcgccgcc ggggccgtga
     9541 ggaccgcgcg ggtcgcgagg atcgccgggg ccgccggaca gctgcgccgc cagctccgcc
     9601 gtgcccggcc ggtggtgcgg ctccttgcgc agcgcccgct ccagcgcggg ccgcagcgcg
     9661 tccggtacgc cggccaggtc cggctcgccg taccgcaccc ggtagagcag gtcggccgcc
     9721 tgacccccgc cgaaggggcc gcgccccgtc agcgcgaaga ccagcacccc ggcgagcgcg
     9781 aagacgtcgc ccgcggcggt gtgttcgccg cccgtggcct gctcgggcga catgtaggcc
     9841 ggggttcccg ccgccgctcc cgtgcgggtc agccgttcgt cgccgatcgc gcgcgcgatg
     9901 ccgaggtcga tgaccttggg gcccgaggcg gagagaagga tgttcgacgg cttcaggtcc
     9961 cggtgcacga catccgagct gtgcagctgc cccagcgcct cgcacagcgc ggcccccagc
    10021 gcccgtacgg ccgcctcggg tagcggcccg cactgctcga cggccgcgtc cagcgcgggg
    10081 ccgagcacgt actcggtcgc cagccacggg gtgggcgcga gcgggtcggc gtcgacgacc
    10141 tcggccccgt gacgcccccc caggacacgc gccgcgtccg tctccagccg gaagcggata
    10201 cggaattcgg gggaggcggc cagccgtgcg tgcgtcgtct tgagcgcgac cgtgcgcccg
    10261 ccggcgtccc gcccgaggta gacggtgccc atgccgccgc tgccgagccg ggcgatcagc
    10321 cggtacgggc cgagctggtg cggatcgtcg taggcgagcg ggagcgcgag gggggtgcgg
    10381 ggggcgggag aagagggcat cgggtcagca gtccacggtg agggggcggt gggggcgggc
    10441 gcggctcagc gtctgtcccc cggcgcggcc agcgccctgg cggactgccg ggcgagcgcc
    10501 gcgatcaccc ggcccggcag ccagccgggg ccgaacgcgt cggcgccccc gtccagcgtc
    10561 gtgaccggcg ccggcacggg cggagcgggc ccggcgggag ggcccggcgg gaccggcgcg
    10621 gcgaggcccg cgcgcagcgc gtcccgcacc gccgaggcct gcggccggtc cgccggatcg
    10681 gcggccagac aggagccgac cgtctcccgc agacccatgg gcagccccga gacgtccggc
    10741 gccaggcgcc ccgtcgccgc gtacgccagc acggcgccga gcccgtacac gtcgccgggc
    10801 gggcgcggcc gtccgcccga gagctgctcg gggggcagcg cctccggcgg cagcccggcc
    10861 acggcccggc ggtcccggcc ctccggggcg agggcccgta cgctgccgaa gccggtgagc
    10921 ctgggcccgt ccgcccccag caggacggtg ccgggggcca ctccggcgtg cgcgacgccc
    10981 tgcacgtgca gggcggcaag ggtcccggcc agctccaggc cgagcgcacg caccgtacgt
    11041 tcgccgaggc ctcggccgtg cgcggccagc gcgccgggca gcggcaccgc gggtgcgtag
    11101 ggcgaggcgt gccagggcgg ttcgccgggg gcgcccgcga agacctccac gagctgctcc
    11161 agcgcggggg cgaacccgcc cagccgccgg gcctgctcgg cctctgccac gaaccgctgc
    11221 ccgtacgcgc cgtccccggc cagctccggc cggggcaggg tgagcagcag cgtgtggtcg
    11281 cccccgggca tgcgcgcgac gaggcgccgc acgggcacgg ggaccccggt gtccgccgcg
    11341 tcgatcccgc cgacggggcg gtagcggccc gggtgccgtg gatcgtcctg gcgcagcggc
    11401 tccattctgc ccccatggtt cagctgaggg tgacgagcct agacgagtga ctccgaaggg
    11461 gcgtcgtccg cccctcgggg gggctgggcg gtgccaggcg cgtcccctga gcccgtaggg
    11521 cccggggaga ccccagcgct tgctgcgctc gcttcgtctc ggctgccttt cccgttcccg
    11581 gatgccgggc gcggtcccaa ggcagggggg agcgcggatg gggcgttccg gtgccggccg
    11641 gcagcgcagc ggggtgcctc ccggcgaagc aaggagcgcc aggagcgtgg ggcgggcctt
    11701 ccgcaggccc gaagggccgg ggggacaggc accggaggca cgcgcgccgg ggcgccgccg
    11761 ccccgtcagg ggttcaggcg ggggcggccg tctcgcagcc gcaggagcgg cggacgatca
    11821 ggccggaggg gaactgccgg atgcgctcgc gccgcgaacc cgccacccgc aggccgtcgt
    11881 ccaggaccag gtcgaccgcc gcgcgggcca tcgcctcccg gtcggagccg accgtcgtca
    11941 gcggcgggtc cgtcagtgcc gcctccttga cgttgtcgaa gccggtgacc gccagctcgc
    12001 ccggcacgtc gatgcccagc tcgcgggcgg cccgcagcac gccgatggcc tggtcgtccg
    12061 tcgagcagaa gagcgcggtg gggcggtccg ggcggcgcag caggtcgagg gcgaggcggt
    12121 aggtgtcgta gcggttgtac ggggccttga agaggcggcc ctccacggag cgcccggcct
    12181 cctgcatggc ccgggtccag ccgtcgatgt ggtcggtgac cgggtcgccg ttcgcggggg
    12241 tggactccat gccgccgagg caggcgacgt cactgtgccc gtgctccagc aggtggcggg
    12301 tggccagttg ggcgccgccc acgtcgtcga gcacgacggc cacgtcgtcg atcgcctcgg
    12361 gccgccggtg cagcaggacg acgcgggcgt cccacgcctc gatctcggtg gccgcgtgct
    12421 cgctgggccc ctggctgatg aggatcaggc cggacacgcg catgcccagg aacgcgcgca
    12481 ggtagtgcac ctcgcgctcg tccaggtagt cggagttccc gacgaggacc atctttcccc
    12541 ggtcggcggc ggcctgctcg accgcgtgcg ccatctcggc gaagaagggc tggcgggcgt
    12601 cggggacgac caagcctatc aggtccgtac gccgcgaggc catcgcctgg gccacccggt
    12661 cggggcggta gcccagctcc gcgatggcgg cgaggacgcg ctccttggtc gccggggcga
    12721 ccggccgcgg cccgttgttg atcacatagc tgaccaccgc ggtcgacgta cccgccagcc
    12781 ttgccacatc gtcccgcgtc accttggcca cggcgctcag tctacgcgcg gcgattcacc
    12841 ccttcgccag ggcgcgtacc ggcctggttc acgcccccgg ccgcgttcct agcgacctcc
    12901 tcggccgcct ccgcgacggc acgggcgtcc gcccgcgtct tgaggtcagc ggcctcccgg
    12961 gcctcccggt cgcgcttgcc gcccttgccc ttctccgagg cgacgaagcg gtagccgacg
    13021 ttccgtacgg tgccgatcag cgactcgtgc tccgggccga gcttcgcgcg cagccgccgc
    13081 acgtgcacgt cgaccgtgcg ggtgccgccg aagtagtcgt agccccagac ctcctggagc
    13141 agctgggccc gggtgaagac ccggccgggg tgctgcgcga ggtacttgag cagctcgaac
    13201 tccttgaagg tgaggtcgag cacgcggccc ttgagcttgg cgctgtaggt ggcctcgtcc
    13261 acggagaggt cgccgttgcg gatctcggtc ggcgcactgt ccgcgccggt ctgctggcgg
    13321 cccatggcca gccgcagccg ggcctcgacc tcggccggcc cggcggtgtc cagcagcacg
    13381 tcgtccacgc cccactcggc cgtgacggcg gcgaggccgc cctcggtcac caccaggagc
    13441 agcgggcagc ccggcccggt ggagcgcagg agttggcaca gcgagcgcac ctgcggcagg
    13501 tcgcggcggc cgtcgacgag tatcacgtcg gcgccggggg tgctgaccag ggcggggccc
    13561 tcggcgggcg agacgcgcac ctggtgcagg aggagtccga gggccgggag cacctcggag
    13621 gacggctgga gggcgttggt gaggagcagc agcgaactca tacgcgtgcg gcacctccgg
    13681 taggcggcgg ttggtgtccg gttcgcttgc ccatgacatc gtgtccttcc tcgggccctg
    13741 cgaggacgcg ggcgacacag ctccgtaccg cccggaaagc gcaaaaggac ccgggggcaa
    13801 cgctgcccgg atccctcatg cgcagcagaa tagcccacat gggcagcgca gcgcagtgtg
    13861 agacgggccg catccgcgtc cgcgagagcc cgcgcgagcg cctccgcggg gtgctccgga
    13921 cggacgacgg agtgcgtatc gaggccgcct acgagcggta cgcggggccc ggtgacggga
    13981 cggcgatcgt gctcgcgcac ggcttcaccg gttccctcga acggcccgcg ctgcgccgcg
    14041 ccgcgcgggt gctgaccgcg cacggggcgg tcgtcacctt ctccttccgc ggccacggcg
    14101 gctccggcgg ccggtccacg gtgggtgacc gggaggtgct cgacctggcg gctgccacgc
    14161 gctgggcccg cgcgctggga caccgccggg tggcgacggt cggcttctcg atgggcggct
    14221 cggtggcgct gcggcacgcg gggctgcggc acgcggggcc ggggggcgcg gggctggagg
    14281 acacgggact ggaggacgcg gggccggggg acgcggggcc gggggacacg gcgcacccgg
    14341 acgccgtcgt cgccgtcagc gccgccgccc gctggtacta ccggggtacg gcgccgatgc
    14401 ggcggctgca ctgggccatc gaacggcccg ccgggcggct cgtctcacgc tggggcctcg
    14461 gcacccggat tcactcgcag gagtgggacc ccgtccccct ccccccggtg gacgccgccg
    14521 cgatgatcac accattgccc ctgctgatcg tgcacggcga ccgggacccc tacttcccgc
    14581 tcgaccatcc ccgctccctc gccgacgccg ccgaccccga ccgcacacgg ctgtgggtcg
    14641 aaccgggctt cgggcacgcc gagaacgccg cgcccgccga gctgctccac cgcgtcggcg
    14701 cgtgggcggc acaggcggcg gcgacgggcg ccgtacccgg gtgacccggc gccgtccgcg
    14761 gcacgggatg gcgcggaacc gcaccgtgcc gcaccccgca cctccgcgag gcgccatcat
    14821 gggtgccgca cccgtgccgc ggccacaccg cgcgcggcgc gcaccggaac ccggcgaacg
    14881 gcgagaggga caccatggcc agcggcacga tccgctactg ggcggcggcc agatccgcgg
    14941 caggcacggc ggaggaggcg taccaggccg gcacgctcgc cgaggcgctc gacgccgccc
    15001 gtgagcggca cgccggttcg ccggagttcg cccgggtgct ggcgcgctgc tcgttcctgg
    15061 tggacgggaa cccggccggg acccgggcgc gggacacggt cacgctgagc gagggcggca
    15121 cggtcgaggt gctcccgccg ttcgcgggcg gtgcccggtg accggccggt acggcgacgg
    15181 gtacggcgcg ccgcagccgt acgagccggc gggcggagcg tgggacgggc cgcaggggcc
    15241 gccgcccgcg gacccgtacg gctatgcgca gcagggtcag ccacagcagc cgcaccagca
    15301 ccagccgcac caccaccagc cgcaccagcc ccggccggtc cggccccagc caggcaccgc
    15361 caccggcccc gccccgctcc cgccgcagcc cgcggccccg cagcccgcaa ccccgcagcc
    15421 cccgccgcac cagcccgccg acgagccccg gcccgaagcc gccccccgcg ccgcgcgcac
    15481 cgggcgcgcc gggcgcgccc gtcccagccc gctgatcgcg ccgggcctcc agcccgccgt
    15541 gctcaccgtc gcgctggccg cgctgctggc cgggacctcc tcgctgcccc ggccggtgtt
    15601 cgcggtggcc gtcgtgctgc tccaggccgt gacggccgcg ggctggtacc ggctcaacgg
    15661 catgtggccc gcccggcagg gcatcgcgct cgcgttcctg gccggtgtcg ccaccgacgt
    15721 cgcgctactg accacgagcc gcgcgcacac ggccacggct gtcgtcggca ccctcggcat
    15781 ctggtgcgtg ctggtgatcg tgctccagct gcgcagccac gccagtccgg acgagcgcct
    15841 ctacgcgctc accgccgggc tcaccgccac cgccctgacg gtgctcgccg ccgggtacct
    15901 ggccatcgcc cgcaccgtcg aggaggccgt gatcgcgggc gccgccgcgg tcgccctcgc
    15961 cacgctcgta cgggcgctgc cgctgccgcc gttcgtctcg ccggtgctcg cggtgctcgc
    16021 gggcggcggg gcgggcgcgc tggcgggcag gtacaccgac ctggggacca cggacgggtc
    16081 gctgctcggc ctggccgccg cggtgtgcgc ggtgaccgga ctgcgggtgg ccagctacga
    16141 ctatccgtcc cgcttcgtgc acatgacggc cggggtcgtg ctgccgctga cgctggcggc
    16201 accggccgtc tacttcctgg gccgcgcgct gggctga
//
