LOCUS       reptomyces_RBGC_360300 16028 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_360300
VERSION     Streptomyces_RBGC_360300
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_002754555.1
  ORGANISM  GCF_002754555.1
            .
FEATURES             Location/Qualifiers
     CDS             2..441
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783417"
                     /pseudo=False
                     /translation="MNAQRLLAPTLRWASAASLAAGGYIHAQLYVDEYRFIHIIGPLFL
                     LQASASFALAALLLMGTPPLLLRAAAAGVALGALAGFTASRTVGVFGFTEHGLQPAPQA
                     LLSLLTETGTLLLLSIWQMTVARQHRAARTPARTPIRERATH*"
     CDS             493..764
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783418"
                     /pseudo=False
                     /translation="MHLEPRPGTAGPSPQLRELRDAVRALLGLDNDTAVIVRQLTCSEP
                     GCPPLETVVAVVPMDGEVHRWTLHRPADEITENDLRATLLPHRPS*"
     CDS             899..993
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783419"
                     /pseudo=False
                     /translation="MPHMTAFAQLASEGTEFVSGHEGGERVDAGA*"
     CDS             complement(1142..1548)
                     /protein_domains="PF07883"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783420"
                     /pseudo=False
                     /translation="MEILKNPATMKLPAQWFTGDAWADVIHRGEEPSRARANMVRFAPG
                     ARTAWHSHGLGQTLHVVSGVALIGTRDGAIIEAHPGDTIGCPPGEEHWHGATPDQFMEH
                     IALWEGDEVDWLEHVTDAEYGGPRTSTRTSH*"
     CDS             complement(1623..1948)
                     /protein_domains="PF02627"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783421"
                     /pseudo=False
                     /translation="MTEKTTQPGPRELFGDVAPALAGYSEDVLFGQAWKSPELSSRDRS
                     LVTVASLITSGSSEQLTFHLPLARQNGVTEAELIETITHMAFYAGWPKAMSALTVAREV
                     FRVA*"
     CDS             2059..2198
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MEPQVTRAWKNSLIRVLAVHPTAGDTIEEADVASKPRTTGARYAS
                     S"
     CDS             2295..3061
                     /protein_domains="PF17765"
                     /protein_domains="PF13560"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783422"
                     /pseudo=False
                     /translation="MLAGVSAEYYARLERGNLSGVSETVLDSLARALQLDEAERAHLDD
                     LARTANTTRRAPRRRPSQPIRPSLQHLLDAMTEAPAFIRNGRLDILATNRLGRALYDPV
                     FADPARPVNLARYEFLNAGAADFLPQLEAQAAGAVALLRTEAGRDPYNRDLTDLIGELS
                     TRSEKFRTLWAAHDVRLHQTGVKHFHHPAVGELSLPFEAMPIPTDPGLTLTALSAEPGT
                     PSHDSLRLLASWAATLDQDGQPDTAAAGGEQSA*"
     CDS             3253..4316
                     /protein_domains="PF00355"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783423"
                     /pseudo=False
                     /translation="MPHMTAFARNQWYVAAYSHEVGRELLGRTILGEPLVFYRTEDDGT
                     AVALADRCVHRRFPLSESRLDGDRIVCGYHGFTYDTTGSCVYVPGQKRIPRTARVASYP
                     VVERDSFVWVWIGDPALADPGNVPRARHMDSPDWTTVCGMEPIDADYGLLVDNLLDLSH
                     ETYLHGGYIGTPEVAETPITTEVDEGAGIVRVSRHMDDAECPPFYARSTGIEGRITRWQ
                     DIEYHAPCLYLLHSRIAPVGVLPEADGSDPNGFHTEITYAITPSSDGHVYDFWAVSRDF
                     ARDDEEVTTFLRDLNHTVVMQDVDALNLLQKTLGTERTGYQELSINIDTGGLAARRILA
                     RLVEEGDKPMEKVL*"
     CDS             4314..4504
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783424"
                     /pseudo=False
                     /translation="VTTPPRFATREIYRVDWIPGTDVLHGTCHCGAEHSAQDPIEMWEW
                     MLGHPEGHRPQESRGLGS*"
     CDS             4502..5436
                     /protein_domains="PF00111"
                     /protein_domains="PF00175"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783425"
                     /pseudo=False
                     /translation="MSSYDFELVVADREFVADGVLSLTLRHTLGEELPAWEPGAHVDVV
                     LGVGLERQYSLCGDPADRRAWRIAVLREPDGRGGSSYVHEQLDAGDKVRVRGPRNHFAL
                     APAARYRFVAGGIGITPILPMLAAAQAAGVEWTLLYGGRTRDSMAFTGELERYGDRVTV
                     APQDECGLLDLDSVLTGVPEGTLVYCCGPGPLLDAVEARCPAGLLRVERFRPKVQETGG
                     DGEFEVELARSGRTLTVPADVSVLDTVRGAGVEVLFSCTEGTCGTCETDVLEGTPDHRD
                     SVLTDEEREAGETMLICVSRCRGKRLVLDL*"
     CDS             5625..6595
                     /protein_domains="PF09084"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783426"
                     /pseudo=False
                     /translation="MRRLLAGLAVGSFLVAASACGSSGGGGASDKNASSGGTTTVKVGV
                     IPIVDVAPLYLGQQKGFYSKRGLKLSMTTAQGGAAIVPGVVSGQFQFGFSNMTSLMIAQ
                     SQNVPVKAVVNGVASTGVAGKDFGAITVKKGSPIKSAKELEGKKVAVNTLKNINETAVR
                     ESVRKAGGDPSKVKFVELAFDQMPAALDSGQIDAAMVVEPALATVKSQGATEIASSLVD
                     VAKGLTVAMYFTSTQYEQKNPDVVKKFQEATAESLAYADAHPDEVRQAVTTYTKIPAAT
                     LAQVTLPKWPAEPNRASIETLEKLGEQDGLFKSTPDLDKLLP*"
     CDS             6593..7365
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783427"
                     /pseudo=False
                     /translation="VRGANAALGAAGLAAFLALGEAVPRLGLVKEAYFPPTSRIADALG
                     QEVTDRAFWTALGDTLTGWALGLAIAIGAGVVVGLLVSVVPYLREATASTIEFLRPIPS
                     VALIPLAVLLYGTELRSVLLLVVYASFWQVLVQVLYGVQDVDPVAEETARSYGLGPWAR
                     VRHVLWPTALPYVMTGVRLAAAVALILAVTAELVIGAPGLGARIAVAESSQAVPDMYAL
                     VVVTGLLGLLINVGARTVERRALAWHQSVRGEVTV*"
     CDS             7363..8141
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783428"
                     /pseudo=False
                     /translation="VRPFLLRLLFVVALPALLVAVWWLASDGSTNVYWPPLRTILRTFP
                     DVWTSERLRSDLVPSVLRLLAGYAAAAVVGVALGTVIGSYRRVRAVCEPVLEFLRAVPP
                     PVLVPVIMLFAGIGDTMKIAVIASGCVWPILLNTVEGVRAVDSVMAETARSYGITGVAR
                     LRSVVLRAASPQIFAGLRQALSIGIILMVISEMFAASNGLGFTIVQFQRSFAIPDMWTG
                     ILVLGLLGFLLSVVFHLVERRVLGWYHGLRVVSRRSP*"
     CDS             8163..8977
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783429"
                     /pseudo=False
                     /translation="MHASLVVSGLNKVYEGSGRRVEAVRDLTFTVEAGELVCLVGPSGC
                     GKTTLLKCMGGLLTPTAGEVRLNDRPVSGPPPGMAFVFQEYGRSLFPWMRVRENVELPL
                     KQKPLSKVRRRELVTDALESVGLTDAAGAYPWQLSGGMQQRVAIARALAYEPDVLLMDE
                     PFAAVDAQTRADLEDLVRGLWRERGITILFVTHDIDEAVYLGERVLILSASPTVVQEQL
                     KVDLPDERDQLHTRVAPRFAELRTHVYEQIQAAKRGTAFGLKTDTPPPR*"
     CDS             complement(8950..11132)
                     /protein_domains="PF12708"
                     /protein_domains="PF00754"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783430"
                     /pseudo=False
                     /translation="MHNSSRTVRRMPTFATVTATTVALAAGTLVMTAPAAHAAVGADLP
                     FTSVEAESATTTGAKIGPDYTQGTLASEASGRQAVRLAAGRRVEFTVPRAANAVNVSYN
                     VPDGQSGTLDVYVNGQKLAKTLAVTSKYSYVDTSWIVGAKTHHFFDNARLLLGQNVQPG
                     DKVAFQATSTQVTVDVADFEQVAAAATRPAGSVSVTDKGADPSGQGDSTQAFRDAISAA
                     RGGVVWIPPGDYRVTSSLNGVQNVTLQGAGSWYSVVHTSRFIDQTGSSGGVHLKDFAVI
                     GEVTERVDSNPDNFVNGSLGPNSSVSGMWLQHLKVGLWLTGNNDNLVVENNRILDTTAD
                     GLNLNGNARGVRVRNNFLRNNGDDALAMWSLYSPDTNSSFENNTISQPNLANGIAIYGG
                     TDLAVTNNLVADTNALGSGIAISNQKFLDPFSPLAGTITVSGNTLVRAGAINPNWNHPM
                     GALRVDSYDSAIEATVNITGTTVTDSPYGAFEFVSGGGHGYATKNITVDGATVRNTGTV
                     VVQAESQGAAKFSNVQATGVGAAGIYNCPYPNGSGAFTLTNGGGNSGWDTTWADCSTWP
                     QPGAGNPDPDPARNLAKGRPATAIGSQDVYTPGKAVDGDANSYWESTNNAFPQAWTVDL
                     GSNQPARRLVLKLPPASVWQARTQTLSVLGGTDGSAYSTVVASKDYRFDPATGNTVTVT
                     LPSGTNLRYLRLNVSANTGWSAAQFSEVEAYLS*"
     CDS             complement(11199..12790)
                     /protein_domains="PF00128"
                     /protein_domains="PF11941"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783431"
                     /pseudo=False
                     /translation="VGQPTHAQNWWRSAVIYQVYVRSFADGDGDGTGDLAGVRAKLPYL
                     AELGVDALWFNPWYLSPMKDGGYDVADYRVIDPAFGTLAEAEKLIAEAKELGIRTLVDI
                     VPNHVSDQHPWFRAALAGGSERELFHFRPGRGEHGELPPNDWPSQFAGSAEPVWTRLPD
                     GTWYLHLFTPEQPDLNWAHPAVRQEHEEILRFWFERGVAGVRIDSAALLAKDPDLPDFV
                     EGRDPHPYVDRDELHDIYRSWRTVADAYDGIFVGEVWLPDTERFARYLRPDELHTAFNF
                     SFLSCLWDAGRLRTSIDETLAEHAPVGAPATWVLCNHDVTRTVTRYGRADTGFDFATKA
                     FGTPTDLALGTRRARAGALLSLALPGAVYLYQGEELGLPEAEIPRDRIQDPMHFRSGGT
                     DPGRDGCRVPLPWTADAPYAGFGGEPWLPQPSGWSAYAADLQAADPGSMLSLYRAALTI
                     RPEFGDGPLTWLPAAEGVLAFARPGQEGRLLCVVNLADAPADLPAHSRLLLGSGPLDPQ
                     GRLPKDTAVWLRD*"
     CDS             complement(12822..13702)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783432"
                     /pseudo=False
                     /translation="MSSGTRTLVSPLTLARPRGKALYWTVFTAVVLLFALAFLFPVYWM
                     VTGAMKSPDEVTRTPPTLVPQTWHLSGYTDAWDLMDLPTHLWNTVVQAAGAWLLQLVFC
                     TAAAYALSKLKPAFGKVILGGILATLMVPAQALVVPKYLTVADLPLIHTSLLNDPLGIW
                     LPAVANAFNLYLLKRFFDQIPRDVLEAAEIDGAGRLRTLWSIVLPMSRPVLGVVSIFAL
                     VAVWQDFLWPLMVFSDTDKQPISVALVQLSQNIQLTVLIAAMVIASIPMVLMFLVFQRH
                     IIAGISAGSTKG*"
     CDS             complement(13700..14670)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783433"
                     /pseudo=False
                     /translation="MKTASKPVVLPPAAVGAPEAPRSAGRRAGGPWRRRLADQSRAYAF
                     LVGGLLCFALFSWYPAIRAVVIAFQKYTPGSPPQWVGTANFTRVFHDPEFTAAWRNTFT
                     FTLLALLIGFAVPFVMALVLNELRHAKAFFRVVVYLPVMIPPVVSALLWKWFYDPGAGL
                     ANEALRFLHLPTSNWSNGADTALVSLVIVATWANMGGTVLIYLAALQGIPGELYEAAEL
                     DGANILQRIRHVTIPQTRFIVLMLMLLQIIATMQVFTEPFVITGGGPENATVTVLYLIY
                     KYAFLYNDFGGACALSVMLLVLLGLFSAVYLRLTRSSGEEYS*"
     CDS             complement(14680..16028)
                     /protein_domains="PF01547"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9783434"
                     /pseudo=False
                     /translation="MRSTGFRRTFVVLTASTLALTAAACGGSDDGSAGGKTRITVNCMP
                     PKSAKVDRSFFEADIKAFEKQNPDIDVVAHDAFPCQDPKTFDAKLAGGQMEDVFYTYFT
                     DSKHVVDINQAADITSYVKDLKSYGTIQQQLRDIYTVDGKIYGVPRTGYSMGLIYNRKL
                     FQKAGLDPDKAPATWEEVRADAKKIAALGGGTVGYADYSAQNQGGWHFTAEMYSQGGDV
                     VTPDGKKASVDTPEGKAVLQNLHDMRWSDNSMGSKQLLVINDVQQLMGSGKLGMYLSAP
                     DNIPILVKEKGGNYDDLALAPMPGGKGTLIGGDGYMFNKKDSPEQIKAGLKWLDHMFLT
                     PGRGFLGDYARAKLNNAPVGLPEPRLFTGAADAKDQQVKKANANVPVENYQAFLDGNQS
                     LQMKIEPPQAQQIYSVLDGAVSAVLTKKDANIDQLLKDASGKIDSILARG*"
ORIGIN
        1 atgaacgccc aaagactcct cgcccccacc ctgcgatggg cgagcgccgc cagcctcgcc
       61 gccggcggat acatacacgc ccagctctac gtcgacgagt accgcttcat ccacatcatc
      121 ggccccctgt tcctgctcca ggcgagcgcc tccttcgccc tcgccgccct gctgttgatg
      181 ggaacaccac ccctgcttct gagggccgcc gcagccggcg tcgcgctcgg cgccctcgcc
      241 ggcttcaccg cctcacgcac cgtgggcgtc ttcggattca ccgaacacgg cctgcagcct
      301 gccccgcagg ccctcctcag cctcctcacc gaaaccggca cgctgctgct cctctcgatc
      361 tggcagatga ccgtggcaag acaacaccgc gctgcccgaa cacccgccag gacacccatc
      421 cgggagcggg ccacccactg aaccaccacg gccaagccgc tcgggatggc ccagaaccaa
      481 ggagtatccc catgcacctg gaaccgcgcc caggaaccgc cgggccgagc ccgcagctcc
      541 gcgaactgag ggatgccgtg cgcgccctgc tcggcctgga caacgacacc gccgtcatag
      601 tccgccaact cacctgcagc gaacccggct gcccaccgct ggaaaccgtc gtcgccgtgg
      661 tgccgatgga cggcgaggtc caccgctgga cactccaccg ccccgccgac gagatcaccg
      721 agaacgacct gagggccacc ctgctccccc accgaccgag ctgaccggaa cagccgatgt
      781 gcggaagccc ctccgcctga cagaagtcgc ctcgccgagc caccgcgcac atcacgaccc
      841 tgttcccgac cacggcacgc ggggcgacgg cgccccgccg acagggacgg gaacgccatg
      901 cctcacatga ccgccttcgc tcaactggcg tccgagggaa ccgagttcgt cagtggccac
      961 gagggcggcg agcgcgtcga cgcgggcgcc tgacgtcggc accaaactca ccgatgagac
     1021 tgtcgatcct gcggccgctc aggacgcggt cgatcaggtc gggcaggaag tggcgtaccg
     1081 gggcggggcc gccacgcagg cctcggtctc agctgacgct caccctcctg tcagctgtga
     1141 tcagtgcgag gtacgggtgc tggtgcgcgg gccgccgtac tcggcgtcgg tgacgtgctc
     1201 cagccagtcg acctcgtcgc cctcccacag cgcgatgtgc tccatgaact ggtccggggt
     1261 cgcgccgtgc cagtgctcct cgccgggcgg gcaaccgatg gtgtcgcccg ggtgggcctc
     1321 gatgatcgcg ccgtcccggg tgccgatcag ggcgactccg gacacgacgt gcagggtctg
     1381 gcccaggccg tggctgtgcc aggcggtgcg ggcaccgggg gcgaagcgga ccatgttggc
     1441 ccgcgcccgg gagggctcct cgccccggtg gatcacgtcc gcccaggcgt cgccggtgaa
     1501 ccactgggcg ggcagcttca tggtcgcggg gttcttgagg atctccatgg tggtacgtac
     1561 tccttgcgtc ggccgccgca gggcggccgt gagtgggtga tgagaacgcg gtccggtggg
     1621 gtcaggccac gcggaacact tcccgggcca cggtcagggc ggacatcgcc ttgggccaac
     1681 cggcgtagaa cgccatgtgg gtgatcgtct cgatgagttc cgcctcggtg acgccgttct
     1741 gccgggccag ggggaggtgg aaggtgagct gctcgctgct tccgctggtg atgaggctgg
     1801 ccacggtcac caggctgcgg tccctcgacg acagctccgg gctcttccag gcctgcccga
     1861 acagcacgtc ctcgctgtag ccggccagcg cgggagcgac gtccccgaac agctcccgcg
     1921 gacccggctg ggtcgtcttc tccgtcatcg ttcgtgtcct ttccacgtgt ccacgtgtcc
     1981 acatgtccac gcgtctcggt ggcgttcatc ggcccgccgc cggcggggct gcgccgacgc
     2041 agcctgcgcc acaaccgatg gaaccgcagg tcacacgcgc gtggaagaac tcgttgatac
     2101 gtgtactggc agtacacccc accgccggag acaccatcga ggaagccgac gtagcctcga
     2161 agccacggac aaccggagcg aggtacgcga gttcctgacc agccgccgtg ccaagatcac
     2221 gccacagcag gcggggctgc ccgtctacac cggcaaccgg cgcgtcaaag ggctgcgcag
     2281 ggaagaagtc gcgatgctcg ccggcgtcag cgccgagtac tacgcccgcc tggaacgcgg
     2341 caacctctcc ggcgtctcgg aaaccgtcct cgactcgctc gcccgcgccc tccagctcga
     2401 cgaggccgag cgcgcccacc tcgacgacct ggcccgcacc gccaacacca cccgccgcgc
     2461 accccgccgc cggccctcgc agcccatccg ccccagcctt cagcacctgc tcgacgcgat
     2521 gaccgaggca ccggccttca tccgcaacgg ccgcctcgac atcctcgcca ccaaccggct
     2581 cggccgcgcc ctgtacgacc cggtgttcgc cgacccggcc cggcccgtga acctcgcccg
     2641 gtacgagttc ctcaacgccg gtgcggccga cttcctgccc cagctggagg cccaggcggc
     2701 cggagcggtg gcgctgctgc gcaccgaggc gggacgggac ccgtacaacc gggacctcac
     2761 cgacctcatc ggcgaactct ccacccgcag cgagaagttc cgcaccctgt gggccgccca
     2821 cgatgtgcgc ctgcaccaga ccggcgtcaa gcacttccac caccccgcgg tcggcgaact
     2881 ctccctcccc ttcgaggcca tgcccatccc gaccgacccc ggcctcaccc tcaccgccct
     2941 cagcgccgaa cccggcaccc cgtcccacga cagcctcaga ctgctcgcca gctgggccgc
     3001 caccctcgac caggacggcc aaccggacac cgcggccgcc ggcggcgaac agagcgcata
     3061 gcgagagcct tcccacgccg ccccgcggtt gcacagcccg aacgcgggtg ccgagttcga
     3121 catacagcct cttcacggaa gcccttccgc ctgacagaag ccgccttgcc gagccaccgc
     3181 gcacatcacg accctgttcc caaccacggc acgcggggcg acggcgcccc gccgacaggg
     3241 acgggaccca catgcctcac atgaccgcct tcgccaggaa ccagtggtac gtcgccgcct
     3301 actcgcacga ggtcgggcgg gagttgctcg ggcggacgat cctcggtgaa ccgctcgtct
     3361 tctaccggac ggaggacgac gggacggccg tcgcgctggc ggaccggtgt gtgcaccgcc
     3421 gcttcccgct ctcggagagc cggctcgacg gcgaccggat cgtgtgcggc taccacgggt
     3481 tcacgtacga cacgaccggc agctgtgtgt acgtgccggg gcagaaacgc ataccgcgca
     3541 cggcccgggt cgcctcgtac cccgtcgtcg agcgggactc gttcgtctgg gtctggatcg
     3601 gcgacccggc gctcgccgac ccggggaacg tcccccgcgc ccggcacatg gactcgccgg
     3661 actggaccac cgtctgcggc atggagccca tcgacgccga ctacgggctg ctggtcgaca
     3721 atctgctcga cctctcgcat gagacgtatc tgcacggcgg ttacatcggc acccccgagg
     3781 tcgccgagac accgatcacc accgaggtcg acgagggcgc gggcatcgta cgggtcagcc
     3841 gacacatgga cgacgccgag tgtccgccgt tctacgcccg ttcgaccggc atcgagggcc
     3901 ggatcacccg ctggcaggac atcgagtacc acgcgccgtg cctgtatctg ctgcacagcc
     3961 ggatcgcccc ggtcggggtg ctgcccgagg cggacggcag cgacccgaac ggcttccaca
     4021 ccgagatcac ctacgcgatc actccgtcga gcgacggcca tgtctacgac ttctgggcgg
     4081 tctcccggga cttcgcgagg gacgacgagg aagtcaccac gttcctgcgg gacttgaacc
     4141 acaccgtggt gatgcaggac gtcgacgcgc tcaacctgct gcagaagacc ctcggcaccg
     4201 agcggacggg ctaccaggag ctgagcatca acatcgacac cggcggtctc gcggcccgcc
     4261 gcatcctcgc ccgcctggtc gaggagggcg acaagccgat ggagaaggtg ctgtgaccac
     4321 gcctccccgc ttcgcgaccc gcgagatcta ccgcgtcgac tggatcccgg gcaccgatgt
     4381 gctgcacggc acctgccact gcggtgccga gcacagcgcc caggacccga tcgagatgtg
     4441 ggagtggatg ctcggccacc ccgaaggaca tcggccgcag gagtcacggg ggcttggatc
     4501 atgagctcct acgacttcga actcgtcgtg gcggacaggg agttcgtcgc cgatggcgtg
     4561 ctctccctca ccctgcgcca cacgctcggc gaggaactcc ccgcatggga gcccggcgcc
     4621 cacgtcgacg tcgtgctcgg ggtcggcctc gagcggcagt actcgctgtg cggggatccc
     4681 gcggaccgtc gggcgtggcg gatcgcggtg ctgcgggagc cggacgggcg cggcggatcc
     4741 tcgtacgtgc acgagcagtt ggacgcgggc gacaaggtcc gcgtccgcgg cccgcgcaac
     4801 cacttcgcgc tcgcgcccgc cgcccgctac cgcttcgtcg cgggcggcat cggcatcacc
     4861 ccgatcctgc cgatgctcgc cgcggcgcag gcggcgggcg tcgagtggac gctgctgtac
     4921 ggcgggcgga cgcgcgactc catggcgttc accggggagt tggagcggta cggggaccgc
     4981 gtgacggtcg ctccgcagga cgagtgcgga ctgctggacc tcgactccgt cctgaccggg
     5041 gtccccgagg gcacgctcgt ctactgctgc ggtcccgggc cgctgctgga cgcggtggag
     5101 gcgcgctgcc ccgccggtct gctgcgcgtc gagcgtttcc ggccgaaggt tcaggagacg
     5161 ggcggggacg gcgagttcga ggtggagctc gcgcgcagcg ggcgtacgct gaccgtcccc
     5221 gcggatgtct ccgtgctcga caccgtgcgc ggcgcgggcg tcgaggtgct cttctcctgc
     5281 accgagggca cctgcgggac ctgcgagacg gatgtcctcg aagggacccc ggaccaccgg
     5341 gactcggtgc tcacggacga ggagcgggag gcgggcgaga ccatgctgat ctgcgtctcc
     5401 cggtgccgcg ggaagcggct cgtgctggac ttgtgagccg cggggccctg gaggcccgcc
     5461 tcggcgcagg cccgtctcgg cgcgggctcg acccgccgac tgtcaacaat attgttggcc
     5521 aaagccattg accccgccgt acgagggctc taccttcccg ctgagcaccc attgcggtgc
     5581 ccgcacagcc tgtcggaaca atgtcgtctg cacaggagga gccatgcgtc gtctgctcgc
     5641 cggtctcgcg gtcggatcct ttctggtcgc cgcgtcggcc tgcggttcgt ccggcggcgg
     5701 tggcgcctcg gacaagaacg cctcgtccgg cggtaccacc acggtcaagg tcggggtcat
     5761 ccccatcgtc gatgtcgcgc ctctctacct gggccagcag aagggcttct acagcaagcg
     5821 cggtctgaag ctgtccatga cgaccgcgca gggcggcgcg gcgatcgtgc cgggagtggt
     5881 cagcggccag ttccagttcg ggttcagcaa catgacctcg ctgatgatcg cccagagcca
     5941 gaacgtgccc gtgaaggccg tcgtcaacgg ggtggcctcg acgggcgtgg cgggcaagga
     6001 cttcggcgcc atcaccgtga agaagggcag cccgatcaag tccgcgaagg aactggaggg
     6061 gaagaaggtc gcggtcaaca cgctgaagaa catcaacgag acggcggtgc gcgagtcggt
     6121 gcgcaaggcg ggcggtgacc cgtccaaggt gaagttcgtc gagctggcct tcgaccagat
     6181 gcccgccgcc ctcgacagcg gccagatcga cgccgcgatg gtggtcgagc cggcgctcgc
     6241 caccgtcaag agccagggcg ccacggagat cgcctcgtcc ctggtcgacg tcgccaaggg
     6301 cctcaccgtg gcgatgtact tcacctcgac gcagtacgag cagaagaacc ccgacgtggt
     6361 gaagaagttc caggaggcga ccgcggagtc cctcgcctac gccgacgccc acccggacga
     6421 ggtacgccag gccgtcacca cgtacacgaa gatcccggcg gcgacactgg cccaggtcac
     6481 ccttccgaag tggccggccg agcccaaccg cgcgtcgatc gagacgctgg agaaactggg
     6541 cgagcaggac gggctgttca agtcgacgcc cgacctcgac aagctgctgc cgtgaggggt
     6601 gcgaacgccg ctctgggcgc cgccgggctc gcggccttcc tcgcgctggg cgaggcggtg
     6661 ccgcggctcg gtctcgtcaa ggaggcgtac ttcccgccga ccagccgcat cgccgacgcg
     6721 ctgggccagg aggtcaccga ccgcgccttc tggacggcgc tcggcgacac cctgaccggc
     6781 tgggcgctgg gcctggcgat cgcgatcggc gcgggggtcg tcgtggggct gctcgtctcg
     6841 gtcgtgccgt atctgcgcga ggccaccgcc tcgacgatcg agttcctgcg cccgatcccc
     6901 tccgtcgccc tgatccccct cgccgtcctg ctctacggca ccgaactccg ttccgtcctc
     6961 ctcctcgtcg tgtacgcctc gttctggcag gtcctcgtcc aggtcctgta cggcgtccag
     7021 gacgtcgacc cggtagccga ggagacggcc cgctcgtacg gcctcggccc gtgggcacgc
     7081 gtccggcacg tcctgtggcc cacggccctc ccgtacgtca tgaccggcgt ccggctcgcc
     7141 gccgcggtgg ccctcatcct cgccgtgacc gccgaactcg tcatcggagc accggggttg
     7201 ggcgcgcgga tcgcggtcgc cgagtcctcg caggcggtcc ccgacatgta cgcgctggtg
     7261 gtggtcaccg gtctgctcgg gctgctcatc aacgtgggcg cccgtacggt ggagcgccgg
     7321 gcgctggcct ggcaccagtc ggtgcgcggg gaggtgacgg tgtgaggccc ttcctgctgc
     7381 ggctgctctt cgtcgtcgcg ttgcccgcgc tgctcgtcgc ggtctggtgg ctggcgtccg
     7441 acggcagtac gaacgtgtac tggccaccgc tgcgcacgat cctcaggacc ttcccggacg
     7501 tctggacgag cgagcggctg cgctccgacc tcgtgcccag cgtgctgcgg ctgctcgccg
     7561 gttacgcggc ggcggccgtc gtgggcgtgg cgctgggcac ggtcatcggc tcgtaccggc
     7621 gggtgcgggc cgtgtgcgag ccggtcctgg agtttctgcg cgcggtaccg cctcccgtcc
     7681 tggtccccgt catcatgctg ttcgccggca tcggcgacac gatgaagatc gccgtgatcg
     7741 cgagcggctg tgtctggccg atcctgctca acacggtcga gggcgtgcgg gcggtcgact
     7801 cggtgatggc ggagacggcg cgttcgtacg gcatcacggg cgtggcccgg ctgcgcagtg
     7861 tggtcctgcg cgcggcgagc ccgcagatct tcgcgggcct gcgccaggcc ctgtccatcg
     7921 ggatcatcct gatggtcatc agcgagatgt tcgcggccag caacggcctc ggcttcacca
     7981 tcgtccagtt ccagcggagc ttcgcgatcc ccgacatgtg gaccggaatc ctcgtcctgg
     8041 gcctgctcgg tttccttctc tcggtcgtct tccacctggt cgagcgccgg gtgctcggct
     8101 ggtaccacgg tctgcgcgtg gtgtcccggc ggtctccgtg aagctcgcga aagggcggtc
     8161 catgcacgcg tctcttgtcg tttccggcct gaacaaggtc tacgagggtt ccggccgccg
     8221 ggtggaggcg gtacgggacc tcaccttcac cgtcgaggcg ggcgaactcg tctgtctggt
     8281 cggcccgtcg ggatgcggca agaccacgct cctgaagtgc atgggcgggc tgctgacgcc
     8341 gacggcgggc gaggtacggc tgaacgaccg cccggtgagc gggccgccgc cggggatggc
     8401 gttcgtgttc caggagtacg gacgcagcct gttcccctgg atgcgggtgc gggagaacgt
     8461 cgaactaccg ctgaaacaga agccgttgag caaggtgcgg cgccgggagc tggtcacgga
     8521 cgcgttggag tcggtcgggc tcacggatgc cgccggggcc tacccgtggc agctgtccgg
     8581 cgggatgcag cagcgcgtcg cgatcgcccg cgcgctcgcg tacgagcccg acgtcctgct
     8641 gatggacgag ccgttcgcgg cggtcgacgc gcagacccgg gccgatctgg aggacctggt
     8701 gcggggcctg tggcgggaac gcggcatcac catcctgttc gtcacccacg acatcgacga
     8761 ggccgtgtac ctcggcgaac gggtcctgat cctctccgcc tcacccaccg tcgtacagga
     8821 acagctgaag gtcgatctcc cggacgagcg ggaccagttg cacacccggg tcgccccgcg
     8881 cttcgccgag ctgcggaccc atgtgtacga gcagatccag gcggcgaagc gcgggacggc
     8941 cttcggcctc aagacagata cgcctccacc tcgctgaact gggctgcgga ccagccggtg
     9001 ttggcgctga cattgagccg gaggtagcgc aggttcgtgc cgctggggag ggtgaccgtc
     9061 accgtgttcc cggtggccgg gtcgaagcgg tagtccttgg aggcgacgac cgtcgagtac
     9121 gccgagccgt ccgtgccgcc caggaccgac agggtctgcg tgcgcgcctg ccagaccgag
     9181 gcgggcggca gcttcagcac gaggcggcgg gcgggctggt tcgagccgag gtccaccgtc
     9241 caggcctgcg ggaaggcgtt gttggtggac tcccagtagc tgttcgcgtc gccgtcgacc
     9301 gccttgccgg gggtgtagac gtcctgcgat ccgatggcgg tggccgggcg gcccttggcg
     9361 aggttgcggg ccgggtcggg gtccgggttc ccggcgccgg gctggggcca ggtggagcag
     9421 tccgcccagg tggtgtccca gccggagttg ccgccgccgt tggtgagcgt gaaggcgccg
     9481 gaaccgttcg ggtaggggca gttgtagatg cccgccgcgc cgacccccgt ggcctgcaca
     9541 ttgctgaact tggccgcgcc ctgcgactcg gcctggacga cgaccgtgcc ggtgttcctg
     9601 accgtcgcgc cgtccaccgt gatgttcttg gtcgcgtagc cgtggccgcc gcccgacacg
     9661 aactcgaaag cgccgtaggg actgtcggtg accgtcgtac cggtgatgtt gacggtcgcc
     9721 tcgatggcgc tgtcgtagga gtcgacgcgc agcgcgccca tcgggtggtt ccagttgggg
     9781 ttgatcgcgc ccgcacgcac gagggtgttc ccggagaccg tgatcgtgcc ggcgagcggg
     9841 gagaaggggt cgaggaactt ctggttggag atcgcgatgc cgctgccgag ggcgttggtg
     9901 tcggcgacca ggttgttcgt caccgcgagg tcggtgccgc cgtagatcgc gatgccgttg
     9961 gcgaggttcg gctgcgagat ggtgttgttc tcgaagctgc tgttggtgtc gggcgagtac
    10021 agcgaccaca tggcgagggc gtcgtcaccg ttgttgcgca ggaagttgtt acgaacccgg
    10081 accccgcgcg cgttgccgtt gaggttgagg ccgtcggcgg tggtgtcgag gatgcggttg
    10141 ttctcgacga cgaggttgtc gttgttgccg gtcagccaga ggccgacctt gaggtgctgg
    10201 agccacattc cggagacgct ggagttcggg cccagtgagc cgttgacgaa gttgtccggg
    10261 ttggagtcga cgcgctcggt gacctcgccg atgacggcga agtccttgag gtggacgcct
    10321 ccggacgagc cggtctggtc gatgaagcgt gaggtgtgga cgacggagta ccagctgccg
    10381 gcgccctgga gggtgacgtt ctggacgccg ttcagcgagg aggtgacgcg gtagtcgccc
    10441 ggcgggatcc acaccactcc ccctcgcgcg gccgagatcg cgtcccggaa cgcctgggtc
    10501 gagtcgccct ggccgctggg gtccgcgccc ttgtcggtga cggacaccga cccggcgggg
    10561 cgcgtcgcgg cggcggccac ctgttcgaag tcggccacat ccacggtgac ctgggtggac
    10621 gtcgcctgga aggccacctt gtcgcccggc tgcacgttct gcccgagcag caggcgggcg
    10681 ttgtcgaaga agtggtgggt cttggcgccg acgatccaac tcgtgtcgac gtaggagtac
    10741 ttggaggtga cggcgagcgt cttggcgagc ttctggccgt tgacgtagac gtcgagggtg
    10801 ccggactggc cgtcggggac gttgtaggac acgttcaccg cgttggccgc gcgcggcacg
    10861 gtgaactcga cgcgccggcc cgcggccagc cgtaccgcct gccgtccgga cgcctccgag
    10921 gcgagggtgc cctgggtgta gtcgggaccg atcttcgcgc cggtggtcgt ggcggactcg
    10981 gcctcgaccg aggtgaaggg caggtcggca ccgacggccg cgtgtgcggc gggtgcggtc
    11041 atcaccagcg tgccggccgc cagggcgacg gtggtggcgg tgacggtggc aaaggttggc
    11101 atgcgcctga cagttctgga gctgttgtgc atgtgctgat cccttcatgg tgggggtgcg
    11161 gggacagcgg tatgcggtcg gcgccgtcga cgcggtctca gtcgcgcagc cagaccgccg
    11221 tgtccttcgg caggcgcccc tgtgggtcca ggggaccgct gccgaggagg agtcgggagt
    11281 gggcggggag gtcggcgggg gcgtcggcga ggttcacgac gcacagcagc cgtccctcct
    11341 gcccgggccg ggcgaaggcg agtaccccct cggccgcggg cagccaggtg agcgggccgt
    11401 cgccgaactc cggcctgatc gtcagggccg cgcggtagag ggagagcatc gagccggggt
    11461 cggcggcctg gaggtcggcg gcgtacgcgg accagccgct cggctgcggc agccagggct
    11521 cgccgccgaa gcccgcgtac ggcgcgtcgg ccgtccacgg gagcgggacc cggcagccgt
    11581 cccggcccgg gtcggtgccg ccggagcgga agtgcatcgg gtcctggata cggtcgcggg
    11641 gtatctcggc ctcgggcagg cccagctcct cgccctggta gaggtagacg gcgccgggca
    11701 gggcgaggga gagcagggct ccggcgcggg cccggcgggt gcccagagcg aggtcggtcg
    11761 gggtgccgaa ggccttggtg gcgaagtcga agccggtgtc ggcgcggccg tagcgggtga
    11821 ccgtgcgggt cacgtcgtgg ttgcacagca cccaggtggc gggcgcgccg accggggcgt
    11881 gttcggcgag ggtctcgtcg atggacgtcc gcaggcgtcc cgcgtcccag aggcaggaca
    11941 ggaaggagaa gttgaaggcg gtgtgcagct cgtcggggcg cagatagcgg gcgaagcgct
    12001 cggtgtcggg gagccagacc tcgccgacga agatgccgtc gtaggcgtcg gcgaccgtgc
    12061 gccaggagcg gtagatgtcg tggagctcgt cgcggtcgac gtacggatgc gggtcgcggc
    12121 cctcgacgaa gtcggggagg tccgggtcct tggcgagcag ggcggccgag tcgatgcgga
    12181 cgcccgccac gccgcgctcg aaccagaacc gcaggatctc ctcgtgttcc tggcggacgg
    12241 cggggtgcgc ccagttgagg tccggctgct cgggggtgaa caggtggagg taccaggtgc
    12301 catcgggcag ccgggtccag acgggctcgg cggagcctgc gaactgggac ggccagtcgt
    12361 tgggcgggag ttcaccgtgc tcgccgcgtc cgggacggaa gtggaagagc tcacgctcgg
    12421 atcctccggc cagggcggcc cggaaccagg ggtgttggtc ggagacgtgg ttgggcacga
    12481 tgtcgacgag cgtgcggatg cccagctcct tcgcctcggc gatgagtttc tccgcctcgg
    12541 cgagcgtccc gaaggccggg tcgatgacac ggtagtcggc gacgtcgtag ccgccgtcct
    12601 tcatcgggga caggtaccag gggttgaacc acagggcgtc cacgccgagt tcggcgagat
    12661 acgggagttt ggcgcggacg cccgcgaggt cgccggtgcc gtcgccgtcg ccgtccgcga
    12721 agctgcggac gtacacctgg tagatgacgg cggagcgcca ccagttctgg gcatgggtgg
    12781 gctgtcccac ggtgcctgcc tttctgttgc ggggtcggtg tcagcccttc gtgctgcccg
    12841 cgctgatccc ggcgatgatg tgtcgctgga acaccaggaa catcaggacc atggggatac
    12901 tggcgatcac catcgcggcg atgagcacgg tcagctggat gttctgcgac agctggacga
    12961 gcgccacgct gatcggctgc ttgtcggtgt cggagaagac catcaacggc cagaggaagt
    13021 cctgccagac ggcgaccagg gcgaagatcg acacgacgcc gaggacgggg cgggacatgg
    13081 gcagcacgat ggaccagagg gtgcgcagcc gtccggcacc gtcgatctcg gcggcctcca
    13141 ggacatcacg cgggatctgg tcgaagaagc gcttgaggag atagaggttg aaggcgttgg
    13201 ccacggcggg cagccagatg ccgagcgggt cgttgagcag gctggtgtgg atcagcggga
    13261 ggtcggcgac ggtcaggtac ttcggtacga ccagcgcctg cgccgggacc atcagggtgg
    13321 cgaggatgcc gccgaggatc accttgccga acgccggctt cagcttggag agggcgtacg
    13381 cggcggccgt gcagaacacg agctggagca gccaggcgcc ggcggcctgc accaccgtgt
    13441 tccacaggtg ggtgggcagg tccatcaggt cccaggcgtc ggtgtagccg ctgagatgcc
    13501 atgtctgggg cacgagggtc ggcggggtcc gcgtcacctc gtccggggac ttcatcgcgc
    13561 cggtgaccat ccagtagacc gggaagagga aggcgagcgc gaagagcagg acgacggccg
    13621 tgaagacggt ccagtagagg gccttgccgc gggggcgggc gagggtgagc ggggagacca
    13681 gggtgcgggt gccgctgctc atgagtactc ctcccccgac gagcgggtca gccgcagata
    13741 gaccgcggag aagaggccga gcagcacgag gagcatgacg ctcagcgcgc acgcgccgcc
    13801 gaagtcgttg tagaggaacg cgtacttgta gatgaggtag aggacggtga ccgtggcgtt
    13861 ctcggggccg ccgccggtga tgacgaacgg ctcggtgaag acctgcatcg tggcgataat
    13921 ctgaagcagc atcagcatga ggacgatgaa ccgggtctgt gggatcgtca cgtgccggat
    13981 gcgctggagg atgttcgcgc cgtccagttc cgccgcctcg tacagctccc ccgggatgcc
    14041 ctggagcgcg gccaggtaga tcaggaccgt gccgcccatg ttggcccagg tcgccacgat
    14101 gaccagggag acgagcgcgg tgtcggcgcc gttggaccag ttcgaggtgg gcaggtgcag
    14161 aaagcgcagc gcctcgttgg cgaggcccgc tccgggatcg tagaaccact tccacagcag
    14221 ggcgctgacc accggcggga tcatcaccgg caggtacacc acgaccctga agaaggcctt
    14281 cgcgtgccgg agttcgttga ggaccagggc catcacgaac gggacggcga agccgatgag
    14341 cagggcgagg agcgtgaagg tgaacgtgtt gcgccaggcc gcggtgaact ccgggtcgtg
    14401 gaagacacgg gtgaagttgg cggtgccgac ccactggggc ggtgagcccg gcgtgtactt
    14461 ctggaaggcg atcacgaccg cgcggatcgc ggggtaccag gagaacagcg cgaagcagag
    14521 caggccgccg acgaggaagg cgtacgcgcg ggactggtcg gccaggcgcc ggcgccacgg
    14581 gcctcccgcc cggcgcccgg ccgaccgcgg cgcctccggc gcgccgacgg cggccggagg
    14641 gagtaccacg ggcttcgatg cggtcttcat acgcctggtc agccccgggc caggatggag
    14701 tcgatcttcc cggaggcgtc cttcaggagc tggtcgatgt tcgcgtcctt cttggtgagg
    14761 accgcggaga cggcgccgtc gaggaccgag tagatctgct gggcctgggg cggctcgatc
    14821 ttcatctgca ggctctggtt gccgtccagg aaggcctggt agttctccac gggcacattg
    14881 gcgttggcct tcttgacctg ctggtccttc gcgtcggcgg cgccggtgaa gagccggggc
    14941 tcggggaggc cgacgggggc gttgttcagc ttggcgcggg cgtagtcgcc gaggaagccc
    15001 cttccggggg tgaggaacat gtggtcgagc cacttcaggc cggccttgat ctgctcgggg
    15061 ctgtccttct tgttgaacat gtagccgtcg ccgccgatga gcgtgccctt gccgccgggc
    15121 atgggcgcga gggcgaggtc gtcgtagttg ccgcccttct ccttgacgag gatcgggatg
    15181 ttgtcgggcg cggagaggta catgccgagc ttgccggagc ccatcagctg ctggacgtcg
    15241 ttgatgacga ggagctgctt gctgcccatg gagttgtcgc tccagcgcat gtcgtgcagg
    15301 ttctgcagga cggccttgcc ctccggggtg tcgacgctgg ccttcttgcc gtccggcgtg
    15361 acgacgtcgc cgccctgcga gtacatctcg gcggtgaagt gccagccgcc ctggttctgg
    15421 gcgctgtagt cggcgtagcc gacggtgccg ccgccgagcg cggctatctt cttggcgtcc
    15481 gcgcgcactt cttcccaggt cgccggggcc ttgtcggggt cgagtccggc cttctggaag
    15541 agcttgcggt tgtagatgag tcccatcgag tagccggtgc gcggcactcc gtagatcttg
    15601 ccgtcgacgg tgtagatgtc gcgcagttgc tgctggatgg tgccgtagct cttgaggtcc
    15661 ttgacgtacg acgtgatgtc ggcggcctgg ttgatgtcga cgacgtgctt ggaatcggtg
    15721 aagtacgtgt agaagacgtc ctccatctgg ccgccggcga gcttggcgtc gaacgtcttg
    15781 gggtcctggc aggggaacgc gtcgtgcgcg acgacgtcga tgtccgggtt ctgcttctcg
    15841 aacgccttga tgtcggcctc gaagaacgag cggtcgacct tggcgctctt cggaggcatg
    15901 cagttgaccg tgatgcgggt cttgccaccc gcggagccgt cgtcgctgcc accgcaggcg
    15961 gcggcggtga gcgcgagggt ggacgccgtg agcacgacga aggtacggcg gaacccggta
    16021 cttctcat
//
