LOCUS       reptomyces_RBGC_406448 17533 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_406448
VERSION     Streptomyces_RBGC_406448
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001705785.1
  ORGANISM  GCF_001705785.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..456)
                     /protein_domains="PF13404"
                     /protein_domains="PF01037"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8997818"
                     /pseudo=False
                     /translation="VRLNDLDERIVHALAEDARRSYADIGELVGLSAPAVKRRVDRLRA
                     EGVITGFTVRVDPAAMGWETEGFIELFCRHNTSPADIRRGLSRYPEVVSASTVTGDADA
                     IVQVFASDMRHFERVLERIAGEAFVERTKSVLVLSPLLRRFSSGAPA*"
     CDS             complement(468..1939)
                     /protein_domains="PF13520"
                     /protein_domains="TIGR00909"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8997819"
                     /pseudo=False
                     /translation="VLEHGAAPPATQQPESDPPVGGLGARLMRRKPVERLVAEGGQGEG
                     GSLRRSMGVWQLTMISIGATLGTGIFVVLGEAVPDAGPAVVVSFVIAGLTALFSALSYA
                     ELAGTIPVSGSSYSYAYATMGELIAWVCGWCLILEYGVSVAAVAVGWGEYLNELLDGAF
                     GVTIPDALAAPPGDGGIFNLPGLLVVLLAMAFLLGGARESARANAIMVGVKIAALVLFC
                     AVAFTGIRAGNYTPFMPLGMAGVSAAGATLFFSYIGFDAASTAGEEARNPQRDLPRAIM
                     FSLVIVTALYCLVAAVAVGALPWKRFSGSEAALASIMKDVTGQSFWAVLLAAGAVVAIA
                     SVVLTVLYGQTRILFAMSRDGLVPKVFSTVHARTGVPRANTVIVSLFCGVLAAAVPLGQ
                     LADATSIGTLFAFALVNIAVIVLRRTRPAMARTFRVPLSPLFPLIGFALCLWMMGSLRA
                     VTWVVFGGWMAIGLVLYFGYGMRRSRLATAEK*"
     CDS             2240..2445
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8997820"
                     /pseudo=False
                     /translation="VTTDSLQPPDHARPGAEPVFRPRDQGGDSERHPLAYRARVWEDFL
                     RALGRIEADFLQHSDTTEPGVTA*"
     CDS             2443..3206
                     /protein_domains="PF10935"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8997821"
                     /pseudo=False
                     /translation="MTYTEPRPGGYGPPPTGHRPAPAPPPGERFEAAVDYQMHPFPLPD
                     PESIESRWDLEGDLARLLQTTSAEEPGQSTGPIGPVTALRTPSPAHVRGRGKRRRVRFR
                     LPRMPWLHVVSLIFAAVTTVIVAMLSVLGGMISYRPLRYLASPSTSESMAAWWPLLVFG
                     PWLVASLSVLRAALHRRGAAHSWAVVVLFSTIAVFLCVAHAPKNAPSVAVAGLPPIAAL
                     VSFHQLVRQITLTSPPRHALPRTRGEQRGAAR*"
     CDS             complement(3434..4896)
                     /protein_domains="PF00478"
                     /protein_domains="TIGR01303"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8997822"
                     /pseudo=False
                     /translation="MRFLEPGTGRHVESSPVPYDLTYDDVFMVPSRSAVGSRQGVDLAS
                     PDGTGTTIPLVVANMTAIAGRRMAETVARRGGLVVIPQDIPIDVVTDVVRWVKNRHLVL
                     DTPIVLAPSGTVADALSLLPKRAHGAGVVVEDGRPVGVVTESDLTGVDRFTQLSEVMSR
                     ELMVLDADIDPQEAFNRLDAAHRKFAPAVGGDGKLVGILTRKGALRATLYTPAVDAAGR
                     LRIAAAVGVNGDVEGRSKALLDAGADTLVVDTAHGHQESMISALKAVRALGPRVPVVAG
                     NVVAAQGVRDLIEAGADIVKVGVGPGAMCTTRMMTGVGRPQFSAVLECAAEARKFGKHI
                     WADGGIRHPRDVAMALAAGASNVMIGSWFAGTYESPGDLQHTADGRPYKESFGMASARA
                     VRNRTSEESAYERARKGLFEEGISTSRMFLDPARPGVEDLIDSIIAGVRSSCTYAGAGS
                     LEEFHERAVVGVQSAAGYAEGQPLHASWD*"
     CDS             5368..5528
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_8997823"
                     /pseudo=False
                     /translation="MSVAVPAESAVEMSEFDLDVRVELDEPVAAQGAASVTPGASIIWC
                     TVAAPACG*"
     CDS             5631..8767
                     /protein_domains="PF04738"
                     /protein_domains="PF14028"
                     /protein_domains="TIGR03891"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8997824"
                     /pseudo=False
                     /translation="MAADHALFHAEPTGLLRVPLLPHSATGTRAQLDPRDREQVRRYLD
                     ALLSDRRVEEALAVSSPSLRRAVRALRAGAPMKAGALRKLTLSATRYVLRAASRATPFG
                     LLAGVAPVSFGEGCQVRMGTSHRKAVRPDGGWLTGVLAAWEGDPEVLRALRVVVNDLGF
                     ARGQRWVLPCGYDAKDPAGPDERAAGERRHEGRSAQEVSVRHTAAVRTVLAAARHPCPA
                     GDLLKVLDEAYPSVPASAKEGLLAELVRRGFLLTELRPPLGETDPLRYAVDVLEAVGRA
                     DKARELAAIGDLLQEYGAERLGAGLGRWQTAVDAMGGLRADDRPVQVDMRLDADVTLDR
                     EVLREAERAATALCLAAPDTRPAPELREYRDAFVERYGTGRAVPLADVLDPHTGLGPPA
                     DYDHPRSERRTAEPGERSERDRARDEFLAELALAAIGSGDREVVLDDTALDRLRGPGAP
                     PPAALELCAHLTAPSQRALEQGDFALVLSPWTGSPAPGALFGRFAYLLDDVEAVGELAR
                     RSAAGSAPDGALQAHLDFLPLTGRDTNVARVRPFWTERVAVGCFADRASPAVRGMADLA
                     LAADPDRLYLVDASTGQEISPRLPTMLDPRRAPAAVRLLREVPTMGSWPSCVWSWGRLA
                     TLPHLPRVRYGRTVLAPARWRLTDPGLSDASLPDAEWERRLDAWRARWHVPDRVAVGEG
                     DHRVELDLTAPLHRMLLRRELVRGKDVTAYETPEEAGAGHGWLATASGAFSSELVIPLV
                     PARPAPAGSPAVRAPARRIRPVGPPVPRHSREWLYGKLYTYANRQDEVLAEHLPRLLAA
                     LPPGVDRWFFIRYTDPAGSHLRLRFHGDPATLHGELTPGVLDWVERVRDLRLAGAFVLD
                     GYEPETHRYGGPQAIEAAETVFHHDSVAVLEQLRLRASGAVTAPPEVLAAANCLDLVRQ
                     VHGDRWTDWWLRNPREEEHHASFREHRTAALRLLDGGLRAAFPAEGADAALAAIDARAA
                     AMRAYASVAADGSVLASVLHMHHNRLIGTSHTSEGRSLAVARGLAQVEHGRRRHRG*"
     CDS             8765..10071
                     /protein_domains="PF05147"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8997825"
                     /pseudo=False
                     /translation="MTVTPAARWDADTVVAEIAARIRDHATDTATGPQAFTAAGLGMGA
                     SGAALLLSELSKGDPGLRTAVHALLAAEAGFTGAKGSGLITGLAGLGFAAKHAARSPRD
                     YATVRGRVDAALRQRLKAVLDAEYDRMESGVPGADRGDFDVVSGVTGLGRYFLAEPSAP
                     DAVHDVLRYLVALTEPVKAGAGPLPGWFSPPWPAAVDPRRREWVLDLGLAHGVAGPLAL
                     LSLCWTRGLRVPDHDTAIRRIARWLMSWRQEHPDTGAGPGWPGTVSADQELAPARPVLE
                     PRRASWCYGTPGIARALHLAGVALGEDAWVHAAAEAMRAVFARPDGLRGLDDPGLCHGL
                     AGLARITGRMAAELDDPSLSARAEEIAERLCARFDPGAAFGFPTAPVPAHRPEPLDAPT
                     FLEGAAGVALVLLGGSTPPGATANGEVPWDAALLLV*"
     CDS             complement(10491..11506)
                     /protein_domains="PF04198"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8997826"
                     /pseudo=False
                     /translation="VSTGRSATRMGPAELVQAAAMARRFYLEGKSKIQIAEEFGVSRFK
                     VARVLETALERDLVRIEIRVPAELDAERSDALRARYGLRHAVVVESPADAEADTPDPEN
                     LGEVAADLLGELVTEGDVLGLAWGRSTIHMAAALHQLPPCTVVQLTGVYDAGTAERGSV
                     EAVRRAAAVSGGEAHPIYAPMLLPDTATADALRGQTGIARAFEYFDKVTVACVSIGSWE
                     AGISTVYDMLSEEERAHYESLGAAAEMSAHLFDAEGRRIGRDLGERCITVEADRLRRIP
                     EVVAIAGGRRKAEAIGAVLRSGLVTSLVTDTAAADYLLAETTPGARPALDRADPDGA*"
     CDS             complement(11592..12289)
                     /protein_domains="PF00834"
                     /protein_domains="TIGR01163"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8997827"
                     /pseudo=False
                     /translation="MALQINPSILSADFSRLADEAKAVEGADWLHVDVMDNHFVPNLTL
                     GVPVVESLSKATDTPLDCHLMIEDPDRWAPQYIEAGAGSVTFHVEAAAAPVRLAREIRA
                     KGARASMALKPATPIEPYEDLLPELDMLLVMTVEPGFGGQAFLDIMLPKIRRTRQLIDK
                     HGLELWLQVDGGVSAATIERCAEAGADVFVAGSAVYGAQDPAKAVTELRHLAEKATTAP
                     GTGDGLVTGR*"
     CDS             12416..13455
                     /protein_domains="PF13354"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8997828"
                     /pseudo=False
                     /translation="MTQHAIPRHHRAAVCAALAAAVATAPVAGAGPARAASATTSTARA
                     ASATTSTAPATSGAPATSATAPAASAVATAPRPVCVSHQPGLAGKLSRDIAAALRGRSA
                     TTALSLRDHTTHTRCTLRANQGFDSASVVKVTVLATLLWDAQHHHRALTKREKTLATAM
                     ITKSDNASTSTLWKQLTPAGIAAFLRTAGMADTVPGKDGYWGLTRITANDQERLLDLIT
                     HPNTVLSDASRGYLLSLMGKVVHAQRWGTPAGAPGDTRIHVKNGWLKRSTHGWRVHSVG
                     AFTGGGHDYTLTVLTQDDRTMKAGVATIEAVARAVHKDLNPTARADRLYTPTDRPQEAL
                     PAVPGE*"
     CDS             complement(14078..15549)
                     /protein_domains="PF01189"
                     /protein_domains="PF01029"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8997829"
                     /pseudo=False
                     /translation="VTDQSRRRRPTAPNRPGKPYRRPQKDPVRILAFEALRAVDERDAY
                     ANLVLPPLLRKARESAEAGSGPRFDARDAALATELVYGTLRHQGTYDAIIAACVDRPLR
                     EVDPPVLDVLSLGAHQLLGTRIPTHAAVSASVELARVVLGDGRAKFVNAVLRRIATHDL
                     DGWLERVAPPYDEDPEAHLGVRHSHPRWVVSALWDALGGGSAAMEELLAADNERPEVTL
                     VARPGRSTTGELLAAVGEGAAVPGRWSPYAVRLTEGGEPGALEAVREGRAGVQDEGSQL
                     VALALANAPLEGEDRRWLDGCAGPGGKAALLGALAAERGAWLLAAEKQPHRARLVARAL
                     AGNPGPYQVIAADGTRPPWRPGGFDRVLVDVPCTGLGALRRRPEARWRRRPEDLDGFAP
                     LQRGLLREALAAVRIGGVVGYATCSPHPAETRAVVEDVLKGRGGPAAGAEWIDARPLMP
                     GVPELGDGPDVQLWPHRHGTDAMYLALLRRTG*"
     CDS             complement(15594..17533)
                     /protein_domains="PF00664"
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8997830"
                     /pseudo=False
                     /translation="MDMQATAWQSLYRTAHAADDRRPFSRETLRRIGAFARPHRRPLLL
                     FLVLSTVTAVLAVATPLLAGRVVDAIVHRSGQDTVLGLAGLIAAIAVAEAALGLLTRWL
                     SANIGEGLILDLRTAVFDHVQRMPVAFFTRTRTGALVSRLNNDVIGAQRAFSDTLSGVV
                     GNIVTLLLTLAVMIGISWQITLVTLLLLPLFLLPARRVGGRLARLRREAAAHNAAMSTQ
                     MTERFSAPGATLVKLFGRPAEESAEFAARTRRVRDIGVRTAMVQVSFVTALTLVSALAL
                     ALVYGLGGWFALHGRLDPGAVVSLALLLTRLYAPLTALAGARVEVMSALVSFERVFEVL
                     DLEPLISEKPDATEVPEGPVSVEFDRVDFGYPAADKVSLASLEEVATLDTRGGVQVLHQ
                     VSFRAEPGQMVALVGSSGAGKSTIAQLLPRLYDADGGAVRLSGVDVRDLTAASIRATLG
                     MVTQDGHLFHDSIRANLLLARPEATDEELWEALRRARLEGLIAALPDGLDTVVGERGYR
                     LSGGERQRLTIARLLLARPRVVILDEATAHLDATSEAAVQEALAEALAGRTAVVIAHRL
                     STVRAADLILVVEDGRIVERGTHSALLAAGGRYEELYRTQFEQSAAVREEFAADGTAGP
                     GGPATAKTPAT*"
ORIGIN
        1 tcaggcgggt gcccccgagc tgaaccgccg cagcaggggc gacagcacca gcaccgactt
       61 cgtgcgctcc acgaacgcct cccccgcgat ccgctccagc acccgctcga agtggcgcat
      121 gtcggaggcg aagacctgga cgatggcgtc cgcgtcaccg gtgacggtcg acgcggacac
      181 cacctcggga tagcgggaca ggccccggcg gatgtcggcc ggggaggtgt tgtggcggca
      241 gaagagttcg atgaagccct cggtctccca gcccatcgcc gccgggtcga cccggaccgt
      301 gaagccggtg atgactcctt ccgcgcgcag ccggtccacc cgccgtttga cggcgggcgc
      361 ggacagtccg accagctcgc cgatgtcggc gtaggagcgg cgggcgtcct cggcgagggc
      421 gtggacgatg cgttcgtcga gatcgttcag tcgcactgcg ggggagtcac ttctctgccg
      481 tggccagtcg ggatcggcgc atgccgtacc cgaagtacag cacaaggccg atcgccatcc
      541 agccgccgaa gaccacccag gtcactgccc gcaggcttcc catcatccac aggcacagcg
      601 cgaagccgat cagcgggaag agcggggaca gcggcacccg gaaggtgcgg gccatggccg
      661 gccgggtccg gcgcagcacg atgacggcga tgttgaccag cgcgaaggcg aagagggtgc
      721 cgatgctggt ggcgtcggcg agctggccga gcgggaccgc ggcggcgagg accccgcaga
      781 agagcgagac gatgacggtg ttggcgcggg gcaccccggt ccgggcgtgg accgtggaga
      841 agaccttggg caccagcccg tcccgggaca tcgcgaagag gatgcgggtc tgcccgtaga
      901 gcacggtcag caccacggag gcgatcgcga cgaccgcgcc ggcggcgagc agcacggccc
      961 agaagctctg cccggtgacg tccttcatga tcgaggcgag cgcggcctcg gagccggaga
     1021 accgcttcca cggcagggcg cccaccgcca cggcggcgac caggcagtag agcgcggtca
     1081 cgatgaccag cgagaacatg atcgcgcggg gcaggtcgcg ctgggggttc ctggcctcct
     1141 caccggccgt ggaggcggcg tcgaagccta tgtaggagaa gaagagggtg gcgccggcgg
     1201 cgctgacgcc cgccatgccc agcggcatga acggggtgta gttgccggcc cgtatcccgg
     1261 tgaaggcgac ggcgcagaag aggaccagtg ccgcgatctt cacccccacc atgatcgcgt
     1321 tggcacgggc gctctccctg gcgccgccca gcaggaacgc catggccagc aggaccacca
     1381 gcagtccggg cagattgaag atcccgccgt ccccgggcgg tgcggccagg gcgtcgggaa
     1441 tggtgacgcc gaaggctccg tcgagcagtt cgttgaggta ctcgccccag ccgacggcga
     1501 cggccgccac cgagacgccg tactccagga tcagacacca gccgcagacc caggcgatca
     1561 gctcgcccat ggtggcgtag gcataggagt aggaggagcc ggagaccggg atggtgcccg
     1621 ccagctcggc gtacgacagc gccgagaaca gcgcggtgag cccggctatg acgaaggaca
     1681 cgacgaccgc gggcccggcg tccggtacgg cctcgccgag caccacgaaa ataccggtgc
     1741 ccagggtggc accgatgctg atcatggtga gctgccagac gcccatcgag cgccgcaggc
     1801 tcccgccctc cccctgacca ccctcggcga ccagccgctc caccggcttg cgccgcatca
     1861 gccgggcgcc cagcccgcca accggagggt ctgattccgg ttgctgggtg gcgggcggtg
     1921 ctgcgccgtg ctccaacact tgggtggctc ctttatcgct gccatcaggt ggtggcgacc
     1981 gactgcggac atacgggtgc ccggggggca aacccgcagg tgggaatcgc cgagcagccg
     2041 gtcccgccac tccacgtcag cgcaagaccc tatgagccgt ccgccgacgg ccgtaatgca
     2101 ccatggttgc gcatccccgt cgcgacgttg cgcgcggggg cgctcggcgg ggaattgttg
     2161 cgagacactg cgcgagtcag cgcgcgtttc acccgaatgc cgcgatactg caccatttta
     2221 gcggtcgttg gtggggacgt gaccactgac agcctgcaac cacccgatca cgcccgcccc
     2281 ggtgccgaac ccgtgttccg gccccgcgac caggggggtg acagcgagcg ccatccgctc
     2341 gcataccgcg cgagagtgtg ggaggacttc ctccgggcgc tgggccggat cgaggcggac
     2401 ttcctccagc actccgacac cacggaaccg ggcgtcacgg catgacgtac accgagccga
     2461 ggccgggcgg ctacgggccc cctcccaccg gccaccggcc cgcccccgcg ccccctcccg
     2521 gggagcggtt cgaggcggcc gtcgactacc agatgcatcc tttcccgctg cccgatccgg
     2581 agagcatcga gagccgctgg gacctggagg gagacctggc ccggctgctc cagaccacct
     2641 ccgccgagga gccggggcag agcaccggcc ccatcggacc ggtcaccgcc ctccgcaccc
     2701 cctcccccgc gcatgtgcgc gggcgcggca agcgccgccg ggtccggttc cggctgccga
     2761 ggatgccgtg gctgcatgtg gtgagcctga tcttcgcggc ggtcaccacg gtcatcgtcg
     2821 ccatgctgag cgtgctgggc ggcatgatct cctaccgccc gctgcgctac ctggcctccc
     2881 cgagcacctc ggagtccatg gcggcgtggt ggccgctgct ggtcttcgga ccctggctgg
     2941 tcgcctcgct gtcggtgctg cgggccgccc tgcaccggcg gggcgcggcg cactcctggg
     3001 ccgtggtggt gctcttctcc accatcgcgg tgttcctgtg cgtcgcacac gccccgaaga
     3061 acgcgcccag cgtggccgtg gccggtcttc ccccgatcgc cgcgctggtc tccttccacc
     3121 agctggtgcg gcagatcacc ctcaccagcc cgccgcgcca cgcgctgccc cgcacccggg
     3181 gcgagcagcg cggggcggcg aggtgaggca ccaccgcgac acaccgccgt ggcccccctt
     3241 tccggggggc tcggtccgcc tccggggcgc cgtggtctcc cccggctgcc gccgggaggc
     3301 gcccggcggc cggtggcccc aggcgcccgg aggcaccggg cacggctctt cggcccgcct
     3361 ccggcccccg ccggcaggcg tccccggccg gaagaccccg gcgccccgcc aggctccccg
     3421 gcgccccggg ggtcagtccc aggaggcgtg gagcggctgg ccctccgcgt agcccgcggc
     3481 gctctgcacg cccaccacgg cccgctcgtg gaactcctcc agcgacccgg cgcccgcgta
     3541 ggtgcaggag ctgcgcacgc ccgcgatgat cgagtcgatc aggtcctcga cccccggccg
     3601 ggccgggtcc aggaacatcc gcgaggtgga gatgccctcc tcgaacagcc ccttgcgggc
     3661 ccgctcgtac gccgattcct cactggtgcg gttgcgcacc gcgcgggccg acgccatgcc
     3721 gaagctctcc ttgtacggcc ggccgtcggc ggtgtgctgg aggtcgccgg gcgactcgta
     3781 cgtccccgcg aaccaggagc cgatcatgac gttggacgcc ccggcggcca gcgccatggc
     3841 gacgtcgcgg gggtgccgga tgccaccgtc ggcccagatg tgcttgccga acttccgcgc
     3901 ctcggcggcg cattcgagca ccgcggagaa ctgcggccgg cccaccccgg tcatcatgcg
     3961 ggtggtgcac atggcgcccg gcccgacgcc gaccttgacg atgtcggcac cggcctcgat
     4021 gagatcgcgc accccctggg cggcgacgac gttgcccgcc accaccggca cccgcgggcc
     4081 cagggcccgg accgccttga gcgcgctgat catcgactcc tggtggccgt gggcggtgtc
     4141 caccaccagg gtgtccgccc cggcgtccag gagcgccttc gaacggccct ccacatcgcc
     4201 gttgaccccg acggcggcgg cgatccgcaa ccggcccgcg gcgtccaccg cgggcgtgta
     4261 gagcgtggcg cgcagcgcgc ccttgcgggt caggatgccg accagcttcc cgtccccgcc
     4321 cacggccggg gcgaacttgc ggtgggcggc gtcgaggcgg ttgaacgcct cctgggggtc
     4381 gatgtccgcg tcgagcacca tcagctcccg cgacatcacc tcggacagct gggtgaagcg
     4441 gtccacaccg gtcaggtcgg actcggtcac cacccccacc gggcgcccgt cctcgaccac
     4501 cacccccgcg ccgtgtgccc gcttgggcag cagcgacagc gcgtcggcga cggtcccgga
     4561 cggggcgagg acgatcgggg tgtccagcac cagatggcgg ttcttgaccc agcggaccac
     4621 atcggtgacg acgtcgatcg ggatgtcctg cgggatgacg acgaggccac cgcggcgggc
     4681 caccgtctcg gccatgcggc ggccggcgat cgcggtcatg ttggcgacga ccagcggaat
     4741 ggtggtgccc gtgccgtcgg gcgaggccag gtccaccccc tggcgggagc cgaccgcgga
     4801 gcggctcggc accatgaaca catcgtcgta ggtcaggtcg tagggcaccg gggacgactc
     4861 cacatggcgc cccgtaccgg gctcgaggaa acgcatgagt ctcacattca cgcgaaacga
     4921 cgcaggtcac tcccggggcg gcacaacaaa agacccccgc gttcctctgg ccctccgaag
     4981 aggcgctgcg ggggctgctc cggcgccggc aggcaacctg ccttacgtcg aaacgttacc
     5041 cgagcgtccg cccgagggcg agtggccgca tgccgatgat cgccgtccgc gcgtccacgg
     5101 gcggacggcc cggccatcag cgggatgaga gcgggatgac ggccgggcgt tccaccggcc
     5161 gcgactctct gggggaacgc ttagatccgg actctccgaa ggcttgaaac cgccggtagg
     5221 cgcgtagaca ggagatgcgg gcgctcgaca cgggcggccg ttgtgtacat ccgcgaacgg
     5281 cagccgcgcg tgcccacctg gtgaggtgtg cccgagcggc cctggtgcga acggctgccg
     5341 tcgccccttg atcaaaggag tggatcatgt ctgttgccgt accggccgag tctgccgtgg
     5401 agatgtcgga gttcgacctg gacgtgcgtg tcgagctcga cgagccggtg gccgcgcagg
     5461 gcgccgccag cgtcacgccc ggggcgtcca tcatctggtg cacggtcgcc gccccggcct
     5521 gtggctagtg gataggaggg cggggcccgg accggtgtcc gggccccgcc cggctcgccg
     5581 acagcggaaa ggctcggcgg tgccgagcgt gaacgggaga gacgacacca tggccgctga
     5641 ccacgcgctg ttccacgcgg agcccaccgg gctgctccgt gtccccctcc tgccccactc
     5701 ggccaccggg acccgtgccc agctcgatcc gcgcgaccgc gaacaggtcc gccggtacct
     5761 cgacgcgctc ctgtccgacc gacgggtcga ggaggcgctc gccgtctcca gcccctcact
     5821 gcgccgggcc gtgcgggcgc tgcgcgcggg cgcgcccatg aaggcgggcg ccctgcgcaa
     5881 gctcacgctc tcggcgacgc gctacgtcct gcgggccgcc agccgcgcca cccccttcgg
     5941 actcctcgcg ggcgtcgccc cggtgtcctt cggcgagggc tgccaggtcc ggatgggcac
     6001 ctcgcaccgc aaggcggtgc gcccggacgg cggctggctg accggcgtcc tcgccgcctg
     6061 ggagggcgat ccggaggtgc tgcgggcgct gcgcgtcgtc gtgaacgacc tgggcttcgc
     6121 ccgtgggcag cgctgggtgc ttccctgcgg ctacgacgcg aaggaccccg ccggccccga
     6181 cgagagggcc gccggtgaac ggcggcacga ggggcggagc gcccaggagg tctccgtacg
     6241 ccacacggcg gccgtgcgga ccgtcctcgc cgccgcacgg cacccctgcc cggccgggga
     6301 cctgctgaag gtcctcgacg aggcgtaccc gagcgtcccc gcgtccgcca aggaagggct
     6361 gctcgccgag ctggtccgcc ggggcttcct cctcaccgag ctgcgccccc cgctcggcga
     6421 gaccgatccg ctgcggtacg cggtggacgt cctggaggcc gtgggccggg ccgataaggc
     6481 acgcgaactg gccgccatcg gcgatctgct ccaggagtac ggcgcggaac gcctcggcgc
     6541 ggggctcggc cgctggcaga cggcggtgga cgcgatgggc ggcctgcgcg ccgatgaccg
     6601 gccggtccag gtcgacatgc ggctggacgc cgatgtcacc ctggaccggg aggtgttgcg
     6661 cgaggcggag cgcgcggcca cggcgctgtg cctcgccgca cccgacacgc ggccggcgcc
     6721 ggagctccgg gagtaccgtg acgcgttcgt cgaacgctac ggcaccggcc gggccgtgcc
     6781 gctcgccgac gtcctcgacc cgcacaccgg cctgggcccg cccgccgact acgaccatcc
     6841 gaggagcgag cggcgcacgg cggaacccgg cgagcggagc gaacgcgacc gggcccggga
     6901 cgagttcctg gccgaactgg ccctcgcggc gatcggatcg ggcgaccgcg aggtggtgct
     6961 ggacgacacg gcgctggacc ggctgcgcgg ccccggagca ccgcccccgg ccgcgctgga
     7021 gctctgcgcc catctgaccg ccccctcgca gcgggccctg gaacagggcg acttcgcgct
     7081 ggtgctctcc ccctggacgg ggtcaccggc accgggcgcg ctcttcggcc ggttcgccta
     7141 cctcctcgac gacgtggagg cggtgggcga gttggcgcgc cgttccgccg ccggctcggc
     7201 cccggacggc gcgctccagg cacacctgga cttcctgccc ctgaccgggc gcgacaccaa
     7261 cgtggcccgg gtccggccgt tctggaccga acgggtcgcg gtgggctgct tcgcggaccg
     7321 cgcctcgccc gccgtgcggg gcatggcgga tctcgcgctg gccgccgacc ccgaccggct
     7381 gtatctggtg gacgcctcga ccgggcagga gatcagcccc cggctgccga ccatgctcga
     7441 cccgcggcgc gcccccgcgg cggtccgcct gctgcgcgag gtgccgacga tgggcagctg
     7501 gccctcgtgc gtgtggtcct gggggcgcct ggccaccctt ccccacctgc cccgcgtccg
     7561 gtacggcagg acggtcctgg ccccggcccg gtggcggctg accgaccccg gcctgtccga
     7621 cgcctccctc cccgacgccg agtgggagcg ccgcctggac gcctggcggg cgcgctggca
     7681 cgtgcccgac cgggtggccg tcggcgaggg cgaccaccgg gtggagctgg acctgaccgc
     7741 cccgctgcac cgcatgctgc tgcgccgcga actggtccgg ggcaaggacg tgacggcgta
     7801 cgagactccc gaggaggcgg gggcggggca cggctggctc gccaccgcct cgggggcgtt
     7861 cagcagcgag ctggtgatcc cgctggtgcc cgctcgcccg gcgcccgccg ggtccccggc
     7921 cgtccgggcc cccgcgcggc ggatccgccc ggtcggcccg cccgtcccgc ggcacagccg
     7981 cgagtggctc tacggcaagc tctacaccta cgccaaccgc caggacgagg tgctggccga
     8041 gcacctgccc cggctgctgg cggccctgcc gcccggggtg gaccgctggt tcttcatccg
     8101 ctacaccgat ccggccggct cgcatctgcg gctgcggttc cacggcgacc ccgccacgct
     8161 ccacggtgag ctgacaccgg gcgtcctcga ctgggtggag cgcgtgcgcg acctgcggct
     8221 ggccggggcg ttcgtcctcg acggctacga gccggagacc caccgctacg gcggccccca
     8281 ggccatcgag gccgccgaga cggtcttcca ccacgacagc gtcgccgtcc tggagcagct
     8341 gcgcctgcgg gcgtccggcg cggtcaccgc cccgccggag gtgctcgccg ccgccaactg
     8401 cctcgacctc gtccgccagg tccacggcga ccggtggacc gactggtggc tgcgcaaccc
     8461 gcgcgaggag gaacaccacg cctccttccg ggaacaccgg acggcggcgc tgcgcctgct
     8521 ggacggcggg ctccgcgccg cgttccccgc cgaaggcgcc gacgccgcgc tcgccgccat
     8581 cgacgccagg gcggccgcca tgcgtgccta cgcctcggtg gccgccgacg gctccgtgct
     8641 ggcgagcgtg ttgcatatgc accacaaccg gctcatcggc acctcacaca cctccgaggg
     8701 ccggtcgctg gcggtggcac gcggcctcgc ccaggtcgaa cacggacggc ggaggcatcg
     8761 gggatgaccg tgacaccggc tgcccggtgg gacgccgaca cggtggtggc cgagatcgcc
     8821 gcccgtatcc gcgaccacgc caccgacacc gccaccggtc cccaggcctt caccgccgcc
     8881 gggctcggca tgggcgcctc gggagcggcg ctgttgctca gcgagctgag caagggcgat
     8941 ccgggcctgc gcacggccgt ccacgccctg ctggccgccg aggccgggtt caccggtgcc
     9001 aagggttccg ggctgatcac cggcctggcc gggctcggct tcgccgccaa gcacgccgcc
     9061 cgctcgcccc gggactacgc caccgtgcgg ggccgggtgg acgcggccct gcggcagcgc
     9121 cttaaagccg tcctcgacgc cgagtacgac cgtatggaat cgggtgtccc cggggcggac
     9181 cggggagact tcgacgtcgt ctccggtgtg accggcctcg gccggtactt cctcgccgaa
     9241 ccgtccgccc ccgacgcggt ccacgacgtg ctgcggtatc tggtcgccct caccgagccc
     9301 gtcaaggccg gggccggacc gctgcccggc tggttcagcc ccccgtggcc ggccgcggtg
     9361 gacccgcggc ggcgggagtg ggtgctcgac ctgggcctcg cccacggcgt cgccgggcca
     9421 ctcgcgctgc tgtccctgtg ctggacccgc ggactgcgcg tccccgacca cgacacggcc
     9481 atccgccgta tcgcccgatg gctgatgagc tggcgccagg agcacccgga caccggcgcg
     9541 ggtcccgggt ggcccggtac ggtctccgcc gaccaggaac tggcccccgc ccggccggtc
     9601 ctggagccgc gccgggcgag ctggtgctac ggcaccccgg gcatcgcccg cgcgctccac
     9661 ctcgccggag tggcgctggg cgaggacgcg tgggtgcacg ccgcggcgga ggcgatgagg
     9721 gcggtcttcg cccgccccga cggcctgcgg gggctggacg accccgggct gtgccacggc
     9781 ctcgccgggc tggcccggat caccggacgc atggccgccg agctggacga tccgtcgctg
     9841 tccgcgcggg cggaggagat cgcggagcgg ctgtgcgccc gcttcgaccc cggcgcggcc
     9901 ttcggctttc ccaccgcgcc ggtgccggcg caccggccgg agccgctgga cgcgccgacg
     9961 ttcctggagg gcgcggcggg cgtcgccctc gtcctgctgg gcgggagcac accgcccggc
    10021 gcgaccgcca acggcgaggt gccgtgggac gccgccctgc tgctggtgtg aaccggcggg
    10081 ccgtttcccc cggggccctc ctgacggctc gccgccgtga ggggtctggc gtcccgacga
    10141 gtctggcgcc ctgacgggtc tccgtcctga cgggtctggc gtccgggcgg gtctggcgcc
    10201 ctgacggctc tccgtcctga cgagtctggc accctgacgg gtcggcgtcc ccgacgatct
    10261 ggcttccccg acgatccggc gccccgacga tccggcgccc cgacgatccg gcgccccgac
    10321 gatccggcgc cccgacgatc cggcgccccg acgatccggc gccccgacga tccggcgccc
    10381 cgacgatccg gcgccccgan nnnnnnnnnc cgacgatccg gcgccccgac gatccggcgc
    10441 ccccggcggg tctcggccgg aagggccttc gcccgccgcg gggcgcccgc tacgcgccgt
    10501 ccgggtcggc gcggtccagg gcggggcggg caccgggggt ggtctcggcg agcaggtagt
    10561 ccgccgcggc ggtgtccgtc accaggctgg tgaccaggcc ggacctcagc accgccccga
    10621 tcgcctcggc cttgcggcgg ccgcccgcga tggccaccac ctcggggatc cggcgcagcc
    10681 ggtcggcctc cacggtgatg cagcgctcgc ccaggtcgcg gccgatgcgg cggccctcgg
    10741 cgtcgaagag gtgggccgac atctcggcgg cggcgcccag gctctcgtag tgggcccgct
    10801 cctcctccga cagcatgtcg tagaccgtcg agatcccggc ctcccaggag ccgatggaaa
    10861 cgcacgccac ggtgaccttg tcgaagtact cgaaggcgcg ggcgatgccg gtctggccgc
    10921 gcagggcgtc cgcggtggcc gtgtccggca gcagcatcgg cgcgtagatg gggtgcgcct
    10981 caccgcccga gacggcggcg gcccggcgca ccgcctcgac cgagccgcgc tccgccgtgc
    11041 ccgcgtcgta cacgccggtg agctggacca cggtgcacgg gggcagctgg tgcagcgcgg
    11101 ccgccatgtg gatcgtggaa cgtccccagg ccagccccag cacatcgccc tcggtcacca
    11161 gctcgcccag caggtccgcg gcgacctcgc ccaggttctc cgggtcgggg gtgtcggcct
    11221 cggcgtcggc cggggactcc acgacgaccg cgtggcgcag cccgtagcgg gcgcgcagcg
    11281 cgtcggagcg ctccgcgtcg agctcggcgg gaacccggat ctcgatgcgc accagatcgc
    11341 gctcgagcgc cgtctccagc acccgcgcga ccttgaaacg gctgacgccg aactcctcgg
    11401 cgatctggat cttggacttg ccctcgaggt agaagcggcg cgccatggcc gccgcctgca
    11461 ccagttcggc gggtcccatc cgcgtggctg aacggcccgt cgacaccgcg gtctcctcac
    11521 tattcactgt ccggactcac cgttcatcct gtcagaaacg gcggagttgc ttcgcccttt
    11581 gcccctgagt tcaccgaccg gtgaccaggc cgtctcctgt accgggggcg gtggtcgcct
    11641 tctcggcgag gtggcgcagt tccgttacgg ccttggccgg gtcctgggca ccatagaccg
    11701 ccgagcccgc cacgaacaca tcggcgcccg cctcggcgca ccgctcgatg gtggcggccg
    11761 agaccccgcc gtccacctgg agccacagct ccagtccgtg cttgtcgatg agctgccggg
    11821 tgcggcggat cttgggcagc atgatgtcca ggaacgcctg gccgccgaag ccgggctcca
    11881 cggtcatcac cagcagcatg tccagctcgg gcagcaggtc ctcgtacggc tcgatgggcg
    11941 tggccggctt gagcgccatc gacgcccgcg cgcccttggc ccggatctcg cgggccagcc
    12001 gcaccggggc ggccgcggcc tccacgtgga aggtgacgga accggcgccc gcctcgatgt
    12061 actgcggcgc ccagcggtcc gggtcctcga tcatgaggtg gcagtccagc ggtgtgtccg
    12121 tggccttgct cagcgattcg accaccggga cgccgagggt caggttgggc acgaagtggt
    12181 tgtccatgac gtcgacgtgg agccagtcgg cgccttcgac cgccttcgcc tcatccgcca
    12241 ggcgggagaa gtctgcggac aggatgctgg gattgatctg cagggccatg gctccaagcc
    12301 tcccacgacc ggcggcgttc cagggagccg ggatcatcgc ggaggcacgc ccggtgatcg
    12361 tccggtcagg ctcggatcga cggacggggc cggagacgag atcatgaaga tgccatgacg
    12421 caacacgcga taccccgaca ccaccgcgcc gcggtgtgcg cggcgctggc ggcggccgtg
    12481 gccaccgcgc cggtcgccgg ggcggggccc gcccgggccg cctccgccac cacgtccacc
    12541 gcccgggccg cctccgccac cacgtccacc gccccggcca cctccggcgc cccggccacc
    12601 tccgctaccg ccccggccgc ctccgccgtg gccacggcac cgcgcccggt ctgtgtctcg
    12661 caccagcccg ggctggccgg gaagctgtcc cgggacatcg ccgccgcgct gcgcggccgg
    12721 tccgccacca ccgcgctcag cctccgcgat cacaccacgc acacccgctg caccctgcgc
    12781 gcgaaccagg ggttcgactc ggcgagcgtg gtgaaggtga cggtcctggc gacgctgctg
    12841 tgggacgccc aacatcacca ccgggcgctg accaaacgcg agaagaccct ggccacggcc
    12901 atgatcacca agtcggacaa cgcctcgacc agcacgctgt ggaagcagct cacccccgcc
    12961 gggatcgcgg cgttcctgcg gaccgccgga atggccgaca ccgtgcccgg caaggacggt
    13021 tactggggcc tcacccggat caccgcgaac gaccaggagc gcctgctgga cctgatcacc
    13081 cacccgaaca cggtgctgag cgacgcctcc cgcgggtacc tcctctcgct gatgggcaag
    13141 gtcgtccacg cccagcgctg gggcaccccg gccggtgccc cgggcgacac ccggatccac
    13201 gtgaagaacg gctggctgaa gcggtccacg cacggctggc gggtgcacag cgtcggcgcc
    13261 ttcaccggcg gcggccacga ctacacgctc accgtgctca cccaggacga ccgcaccatg
    13321 aaggcgggcg tggccaccat cgaggcggtg gcccgcgcgg tgcacaagga cctcaacccc
    13381 accgcccgcg ccgacaggct ctacaccccg accgaccggc cccaggaagc gctccccgcg
    13441 gtcccggggg agtgacgaac cgcgcgtcag cggcgatacc gccgaagcga gggcccgctt
    13501 gctggcccaa cacgtccgcg caggcgccga aaggcggcga ccagttcctc atcgggggcg
    13561 ggtacgagga ccggcccacc ccgcccggcc gacggctgac ggatcgcctg gcggcgggtc
    13621 aacggcccca ggacacaagg gaatccgaag gtggtgggca gcacgccgga ccgccgcgag
    13681 aacggctgat caaggtccgg gcccgccgac acgaccggtc acgaacggga cccgccctcc
    13741 gtccgccagg tccggccggc tcccggcggc gatagtgctc actgctggcg gctacggaac
    13801 cgagcattcc ccggcctcgt agctcccctt aggcggtgaa ccggcccgga ccccctcgtt
    13861 cggacctggg ccgcgagtcc gcccggccgc cctgaccggc tgcttcggtg tcaccccggc
    13921 cgggcgcgtc ccccgcaggc ccgtgcacac cgcctgaccg tgatcgtgag cggaccgtcc
    13981 gtcgaggagc ggcgcccggc ccacgggagg gaggacgggg cactcgttcg gaacgggagc
    14041 gggtcactcg ttgtcagaac ccgcaccggc ggccggtcag ccggtgcggc gcagcagcgc
    14101 caggtacatg gcgtccgtgc cgtgccggtg cggccacagc tggacgtcgg ggccgtcgcc
    14161 cagctcgggc accccgggca tcagcggacg ggcgtcgatc cactccgcgc cggcggccgg
    14221 gccgccgcgc cccttgagga cgtcctcgac cacggccctg gtctcggccg gatgcgggga
    14281 acaggtcgcg tagccgacca ccccgccgat ccgcaccgcg gccagcgcct cccgcaacag
    14341 cccgcgctgc agcggggcga acccgtcgag gtcctccggg cggcgccgcc agcgggcctc
    14401 cgggcggcgg cggagcgccc cgaggccggt gcacggcacg tccaccagca cccggtcgaa
    14461 accgcccggc cgccacggcg gccgggtgcc gtccgcggcg atcacctggt acggacccgg
    14521 attgccggcc agggccctgg ccaccagccg ggcccggtgc ggctgcttct cggcggccag
    14581 cagccaggcg ccgcgctcgg cggcgagcgc gccgagcagc gcggccttgc cgccggggcc
    14641 cgcgcagccg tccagccagc gccggtcctc cccctccagc ggggcgttgg ccagcgcgag
    14701 ggccaccagc tggctgccct cgtcctgcac cccggcgcgg ccctcgcgca ccgcctccag
    14761 cgcccctggc tccccgccct cggtgagccg caccgcgtac ggggaccagc ggcccggcac
    14821 cgcggccccc tcgcccaccg cggccagcag ctccccggtg gtggaccggc cgggccgggc
    14881 gacgagggtg acctcgggcc gttcgttgtc cgcggccagc agctcctcca tagcggcgct
    14941 gccgccgccg agcgcgtccc acagggcgga gacgacccag cgcggatgcg agtggcgaac
    15001 gcccagatgc gcctcgggat cctcgtcgta gggcggggcg acccgctcca gccagccgtc
    15061 gaggtcatgg gtggcgatcc ggcgcagcac ggcgttgacg aacttggccc gtccgtcgcc
    15121 gagcaccacc cgggccagct cgacgctcgc ggagacggcg gcgtgcgtgg ggatccgggt
    15181 gccgagcagc tggtgggcgc cgaggctcag cacatcgagc accggcggat cgacctcgcg
    15241 cagcgggcgg tccacgcatg cggcgatgat cgcgtcatag gtgccctggt ggcgcagggt
    15301 gccgtagacc agctcggtgg cgagcgcggc gtcccgggcg tcgaaccgcg gcccgctgcc
    15361 ggcctccgcg ctctcccgcg ccttgcgcag caggggcggg agaacgaggt tggcgtacgc
    15421 gtcccgctcg tcgaccgccc gcaacgcctc gaaggcgagg atccgcacgg ggtccttctg
    15481 cggacggcgg tagggcttgc ctggccggtt cggggcggtg ggacggcgac gacgggactg
    15541 gtcggtcacg gggaatgtgc tccgggggac ggatcgggct gaagggtcca gcctacgtcg
    15601 ccggggtctt ggcggtcgcg gggccaccgg gcccggccgt cccgtcggcg gcgaactcct
    15661 cccgcaccgc cgccgactgc tcgaactggg tgcggtacag ctcctcgtag cggcctccgg
    15721 cggccagcag cgcgctgtgc gtaccgcgct ccacgatccg cccgtcctcc acgacgagga
    15781 tgaggtccgc ggcccgcacc gtggacagcc ggtgggcgat caccaccgcg gtgcgcccgg
    15841 ccagcgcctc ggcgagcgcc tcctgcacgg cggcctccga ggtggcgtcc agatgcgcgg
    15901 tggcctcgtc gaggatcacc acccgggggc gggccagcag cagccgggcg atggtcagcc
    15961 gctggcgctc cccgccggag agccggtagc cgcgttcgcc gacgacggtg tcgagcccgt
    16021 ccggcagggc cgcgatcagc ccctccagcc gggcccggcg cagcgcctcc cacagctcct
    16081 cgtcggtggc ctccggccgg gccagcagca gattggcgcg gatcgagtcg tggaagaggt
    16141 ggccgtcctg ggtgaccatg ccgagggtgg cgcggatcga ggcggcggtc aggtcgcgga
    16201 cgtccacgcc ggagagccgc accgcgcccc cgtcggcgtc gtagagcctc ggcagcagct
    16261 gcgcgatggt ggacttcccg gcgccggagg agcccaccag cgcgaccatc tggcccggtt
    16321 cggcgcggaa ggacacctga tggaggacct ggacgccacc gcgggtgtcc agggtggcga
    16381 cctcctccag ggaggcgagg gagaccttgt ccgcggccgg gtagccgaag tcgacccggt
    16441 cgaactcgac ggacaccggc ccctccggga cctccgtggc gtccggcttc tcgctgatca
    16501 gcggctcgag gtcgagcacc tcgaagaccc gctcgaagct gacgagcgcg ctcatgacct
    16561 cgacccgcgc cccggccagc gcggtcagcg gcgcgtagag ccgggtgagc agcagcgcga
    16621 gcgagacgac cgcgccgggg tcgagccgcc cgtgcagcgc gaaccagccg ccgaggccgt
    16681 agaccagggc gagggccagg gcggagacca gggtcagcgc ggtcacgaag gacacctgga
    16741 ccatcgcggt ccgcaccccg atgtcccgca cccggcgggt ccgcgcggcg aactcggcgg
    16801 actcctccgc gggccggccg aagagcttga ccagcgtcgc cccgggcgcg gagaagcgct
    16861 cggtcatctg ggtgctcatc gcggcgttgt gcgcggcggc ctcgcgccgc agcctggcca
    16921 gccgcccgcc cacccggcgc gcgggcagca ggaagagcgg caggagcagc agcgtcacca
    16981 gggtgatctg ccaggagatc ccgatcatca cggccagggt gagcagcagc gtcacgatgt
    17041 tgccgaccac cccggagagg gtgtcgctga acgcccgctg cgcgccgatc acgtcgttgt
    17101 tgagccggct gaccagcgcg ccggtgcggg tcctggtgaa gaacgccacc ggcatccgct
    17161 ggacgtggtc gaagacggcg gtgcgcagat cgaggatcag cccctcgccg atgttcgccg
    17221 acagccagcg ggtcagcagc ccgagcgccg cctcggccac ggcgatcgcg gcgatgagcc
    17281 cggccagtcc gaggaccgtg tcctgtcccg aacggtggac gatcgcgtcc accacccggc
    17341 cggccagcag cggcgtcgcc accgcgagca ccgccgtgac ggtgctcagc accaggaaca
    17401 gcagcagcgg gcggcggtgc ggacgggcga aggcgccgat gcggcgcagc gtctcgcggg
    17461 agaaggggcg ccggtcgtcc gcggcatggg ccgtccggta aagggattgc caggcggtcg
    17521 cctgcatgtc cat
//
