LOCUS       reptomyces_RBGC_415438 17176 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_415438
VERSION     Streptomyces_RBGC_415438
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000426165.1
  ORGANISM  GCF_000426165.1
            .
FEATURES             Location/Qualifiers
     CDS             2..663
                     /protein_domains="PF00596"
                     /protein_domains="TIGR03328"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893581"
                     /pseudo=False
                     /translation="VSGGLAHGQQTEVADELAALSRQLYERGWMPGTAGNLSVRLPDGH
                     AVITGSGRDKGTLTRHDMALVDTGTGGQLSPGLPRASAETTIHAAVYRTTRARAVVHVH
                     SPYATAVACRAGDPARTRTLPLTGFELLKGLGLKHPAACDLPVFPNWREVPRIAADVAG
                     HLGATADAPPGLLITDHGITTWGDELRQARNRLECLESICQLLLLTGTDFAEPWKRE*"
     CDS             669..1249
                     /protein_domains="PF03079"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893582"
                     /pseudo=False
                     /translation="MTLLQVMPEDDPQNVLLRTEDHGRITEALGDSSVTLRRWPVRGTV
                     TRGTSQEQVLSRYRTEVDELCAHEGLGLVDVAQLHPEDTEEWKAQAAKARSAFLEEHRH
                     GEDEVRFFAHGNGCFYLHIGERVYATVCTAGDLLSVPAGTRHWFDMGPRPEFTAIRFFE
                     KADGWVGDFTGDPIGQRFPRLDALLKAGAA*"
     CDS             1250..2028
                     /protein_domains="PF00702"
                     /protein_domains="TIGR01691"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893583"
                     /pseudo=False
                     /translation="MTAETTPVRAVVLDIEGTTGSASHVHDVLFPYARKRFADWLAAHR
                     GERAHAELLREIRDFTGDAALGEEEAVTALERWSDQDLKAPPLKRAQGLIWADGYARGE
                     LAGHVYDDVPSALALWRHAGIDCFIYSSGSRAAQRDWFAHSNHGDLSGLVCDHFDLLDA
                     GNKHNAESYRNIAEAVRTPPGEILFLSDECRELDAAATAGWQTVAVRRPGDPRGVRVDG
                     HRVVSSLDELRLLSGSRTTETVRRTADVPNSPAERPR*"
     CDS             2026..2846
                     /protein_domains="PF01048"
                     /protein_domains="TIGR01694"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893584"
                     /pseudo=False
                     /translation="MTDDPRLPAADVGVIGGSGFYELLSEAEELRVDTPFGEPADAVTV
                     GTAGGRRVAFLPRHGRGHRFPAHKINYRANMWALRSVGVRQILAPCAAGSLRRDLGPGT
                     VVVPDQLVDRTSGRVQTFYDEGAVHVSFADPYYEPGRSALLKAAAVMGGEAVDGGTMVV
                     VEGPRFSTRAESRWFASQGWSLVNMTGHPEAVLARELDMCYASLALVTDLDAGIGPEDG
                     VAQEDVFALFAQNVERLRRIVLQAVQLLPESVQELPCARATQGMTLPFELP*"
     CDS             complement(2881..3818)
                     /protein_domains="PF00288"
                     /protein_domains="PF08544"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893585"
                     /pseudo=False
                     /translation="VKRSHDVTPRQGLTGTGTAFGTFGELLQGVLPGDGGDFLVTLPVA
                     RWSMATFRQDPGADGITVRPVHKKKALQLAHLIAEEERRPVRGVLTVSSVIPEGKGLAS
                     SSADLVATARAVAKTLTTPMPPGRIERLLARIEPTDGVLYPGIVAFHHREVRLRAVLGS
                     LPAMTVVGIDEGGAVDTVAYNRIPKSYSTAQGYEYARLLDRLADAIPRHDLVEVGRVAT
                     RSALMNQPLRYKRSLEPMREICREVGGLGVAVGHSGTTLGVLLDSRDPSCTRRAMEAAR
                     ACAELADGVAVYRTLSFSGVRAPTAEPLLTV*"
     CDS             4078..4211
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MGGDETDNRSNSSGCDEASRRCLCALVSSGSSGLAALPAVRGGQ"
     CDS             4427..5208
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893586"
                     /pseudo=False
                     /translation="MGEQNRTRTAPSADDPAVAGAWDLHGTLPHTLPADEIIALNTPKA
                     DLHTWRTYAYRDWTFDMPPGVFTPGETSRMIHDRILDGTIPVGGRCYGAMGVGLGVEAV
                     VAGLRGAKEIHAMDIDPESVRAMTDAYERIVGDRPGTLFHPRVSDLFESVPDGARFDVI
                     TFNPPAVRETVSEDPAVVRNVCVGIGIVRRFFDQVVQRNLLAKDGEIYFIVSNTSELRN
                     IVAYAIESGFFPEVIHHQTWDTDDVQTFLFKLRPSAAV*"
     CDS             5221..6227
                     /protein_domains="PF00291"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893587"
                     /pseudo=False
                     /translation="MHSHIAEAIKQPDLIRLEPDLICLRFETMKVYSALGAVRHLLDSE
                     AVNPGDTLIDSSSGIYAQALALACHRYGLKCHIVGSTTVDRTLRVQLEILGATLEQVEP
                     SKNLRLDQELRVCRIAEILESNPSYHWMRQYHDEIHYYGYREVADVMDREIPAGPVTLV
                     GGVGSGASTGAISTYLREASRDVSVVGMQPFGSVTFGSEHVPDPDMIIAGIGSAIEFKN
                     VRHELYDRIHWVNFECALSGSVELLRSTGIFAGLSAGAAYLTSLWERRGNSSRTYVFIA
                     ADSGHRYVEDAYAQHRSAKGIETLRPHEIASLDELKPPWSAASWRDISQPAHGS*"
     CDS             6329..7173
                     /protein_domains="PF04016"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893588"
                     /pseudo=False
                     /translation="MPYPKPHTVAELTEGILEGAYGPDPKDITVTSAFWLYHTTRLAGG
                     DVTYHNHYLLLRVGESFGACSFEAGELSPEFCENASGFTLETLLRNESASVRIAALDAY
                     LSRVRQHREAGEAEPVTLPTGTPEIRARARDAAIAGLLDLEPGAKVALIGVVNPLIEAI
                     RDRGGVCLPCDLNLRTTQWGEPVSDDMTEVLEQADAVVATGMTLGNGTFDLILEHCRQN
                     ALPLVVYAQSGSAVARAFLSSGVSALSAEAFPFSQFSADATVLYRYRADSSAAALEEAS
                     *"
     CDS             7171..8483
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893589"
                     /pseudo=False
                     /translation="LSNGAGTSQMKRDDPDTGEQLPSDLNMTRTLWPILLASAVGLLPF
                     TIFSTYLVPIAGESGSSVAAMGGLRGLGGLAALLVGTALAPLIDRVPKEWAAAGGLGVL
                     AVSAALGASGEYVLLVAFCLLVGAGTAVLNPALTAAAADRFGSGKAASRAATLVTATQS
                     MTAMLAAPVIALPAVFWGWEGDLLAVTVVSLLLAAILLSRRGHSVVEEEAADSGEKLSY
                     FASFKALAAVRGAVPLLLISLLRTAVFMGYLAYLAAYYDSRFQLDPGLFSFVWTLSGAS
                     FFVSNLLTGRLTNSAQPRVRTEHLLLLGLVAAMASVVGFYFTHWLPLALVLTSLHAASH
                     AVVAACAVSLLVRRCGALRGSALSINAAGMSLGVFVGASLGGAGLGLAGYPGIALVFGA
                     LTAVALGAAFLVSRLSGDELTGEDGTENPDSSDTSTTS*"
     CDS             8537..9675
                     /protein_domains="PF01032"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893590"
                     /pseudo=False
                     /translation="MCPSASSAPTVSSDSRTPEGKVGQASGARGSGSSVSRMRLTTTCV
                     VLLALLLVSVVVAIGLGTAVITPPDTARYLWAALSGGKIGASETTTYQIVWEIRTPRVL
                     LAALVGAGLSTIGVAVQAMVRNALADPYVLGVSSGASVGAVGVTVTGGLAGLGVYAMSA
                     GAFMGALAASALVYTAAVSRAGMSPLRLILTGVAMALGFQAVMSVIIYLVPNSEATSTV
                     LYWTMGSFGAATWSALPAVAAAVLLGLVVLRRYSRALDVMALGDETAASLGVDPDRHRK
                     QLLVLVSLVTGAMVAVSGAISFVGLVMPHLVRMVVGSTHARVLAVSPLVGAVFMVWVDL
                     VARTLVAPRELPLGVITALVGVPVFVTLMRRKAYMFGGR*"
     CDS             9678..10495
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893591"
                     /pseudo=False
                     /translation="MDLTLDQLSVVTDGKKLLSDLSLNVPDGRCVGLVGPNGSGKSTAL
                     RCIYRALRPSSGTVRIGEEELSRLRMRRSAQLVAALAQDGEVELDFTVEEVVALGRTPH
                     IRGNHVLSARERELCERAMEQLDISHLARRGVLTLSGGERQRVLVARALVQEPKILVLD
                     EPTNHLDVRHQVELLSLLRSTGLTTLVVLHDLNLAAAACDQLGVLSEGRLVASGTPEKV
                     LTPELVHDVFGVRTTVVCHPLTGDPQLLYSLTLTPASKNGSDTSCTPPGH*"
     CDS             10475..11484
                     /protein_domains="PF01497"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893592"
                     /pseudo=False
                     /translation="MHATRPLNSARRRAVMGSTAAVALLLTGCGADVATDGKKSEKATV
                     KRCGEPVEYTTPQRTVAYEGGSADKLFSLGLTDHVYGYVMPPANPPVKESPWASEYAKV
                     KKLSDDLLNKEVVVDAKADFVVAGWNSGFSDQRGITPEILDKLKIQSFMHTESCYNYPK
                     HPEKKKPFEALYTDLERLGKIFKVEEKATKVVDDLKQREKAVEAKAPKGSPVPVFLYDS
                     GTDQPFTAGNQVPPNDIIKKAGGKNVFSNLDHRWTQVNWESVTKSEPEVIVILDYGDKP
                     AKKKIDFLKKSRQTKELPAVKNNNFFILDYNEGISGPRNIDGLEKFGKYVRKLER*"
     CDS             11589..12991
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893593"
                     /pseudo=False
                     /translation="MDRRGGWSSRQGFGEGAGRCHGQIRRGGHAERAGLAADLAGEFGA
                     ELVRALRAGLAPGRAGAYGSRGPSQLSWYAFAVDYAQAHWLGRAAHTRRENSEALAAIT
                     RAMLLDLPGRPEESLLHRSLQGWAFVVLGPQEGEVPVQARLVLDWVAKASRPLIDLHDP
                     AVARGVLDALRRKRDGTAAARETWRRKRKVLVSALYYAVEQGELGSHPLDNIRGGVSRQ
                     VTKVDPRVVVNPQQARTLITAVTYVGTYHRARGRRLVGFFAGMYYAGLRPEEAAGVVVT
                     DCVLPTSGWGRLVVNRALPQVGKKWTDSGRRHDQRGLKNRPAGETRVVPLPPHLVALWR
                     ESINTFGVADDGRLFFTERGDIIGSTSYYRAWSEARTLALPPQLVASPLAAKPYDLRHS
                     ALSTWLCSGADPAEVAQRAGNSIDVLLTRYAKCLYDRQSITNQRIEHLLRAYDPPAPDD
                     ETATASPEQ*"
     CDS             13502..14436
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893594"
                     /pseudo=False
                     /translation="MSVCVTLVAEAGLRGVTGLKLFTVNGGVAEVSSRLAGRERELHQL
                     VGANLETMLGVRPLASEYSTGPVHGGRIDTLGIDEGGAPVVVEYKRGVDAGVINQGLYY
                     LSWLVDHRAEFEALVRGRLGPTAAGQVLWSAPRLICIAAGFSRYDVHAVREHRRSIDLV
                     SYRFLGSDHFALETVASVGRQAAPTRAAGVPDAGGEAQGRPAGGSLAELREAVGEVLSG
                     LGDDVKRIETQTYRAYRRTQHFACVCPPQETKLLVYLKANPKKVDLIPDFTRDVTERGH
                     HGTGNLEVALRTERDLERADELFRLSYDVS*"
     CDS             14919..15208
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893595"
                     /pseudo=False
                     /translation="VLPESLGDLAGPTSGNVVLPRHIDWGPHYEYDLADEADLILMYER
                     VIREAQSAADLRSYLSADLLLRHWGNLFLPSAVRVAWQTRFPELGPTVAAA*"
     CDS             15297..16003
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893596"
                     /pseudo=False
                     /translation="MTYTPRRPVSELPFGGSDIILRYHLEHPAVPFDFEETLETWSVGI
                     FRYHGEDEACPNCSEEQACEFYESGTPVGDMSFVRIRDYTSDPAWEAADSQSGDIEKVV
                     AVCTDPAYSMTPGLHWSEDFERTIEMPFGDLLIMNRVHIAPEWRGFGIGALAAAEAIRR
                     LRGGCCAVACEPAPTDREFGDDETAFAKARTKIARVWESVGFQPFKNGIYLLDSAMQHP
                     EDCRIAWQEHFAR*"
     CDS             complement(16056..17176)
                     /protein_domains="PF00772"
                     /protein_domains="PF00772"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7893597"
                     /pseudo=False
                     /translation="MPHTPETDEEDFDVEPAPEPPVHYAEQALLGALLLDPEQLARTEA
                     LLPEHFQAASHRAVYAAMRTLTPPEPELHRKEPAWINAVLARAVDEAPGVSTAYLHTCI
                     GACPRPQHAASYAQMIRADHARRTLREHAMRLEQLATDTTLPDPVAAVAEQAGVLARFV
                     DELAGQTRPHPGSLPRTPLPADPPPERTEEALEEERLFLATATDRAGDLKELPLRAEDF
                     ALPLHGQLYQCLTALALRGEVIDPITVLWEAQHHGLLAPSNARPEDVLARLSQPAGSPE
                     HWAEQILQRALLLGAHRTAIRIRAFAEDPANSPHQLATGTRRALADLTAQQARCRLRAP
                     PSTTATTERPRPPSAKPAIHAPPALHASRGNRR*"
ORIGIN
        1 gtgagcggcg gcctcgccca cgggcaacag acggaggtcg cagacgaact cgccgcgctc
       61 tcacggcagt tgtatgaacg cgggtggatg ccgggcacgg ccggcaacct ctccgtacgg
      121 ctgccggacg ggcatgccgt gatcaccggc agcggccggg acaagggcac cctcacgcgg
      181 cacgacatgg cactcgtgga caccggcacg ggcgggcagc tgagtcccgg cctgccacgg
      241 gcttcggcgg agaccaccat ccacgcggcg gtctaccgca ccacccgggc acgggccgtc
      301 gtgcacgtcc actcgcctta cgccaccgct gtcgcctgcc gcgcgggtga cccggcgcgg
      361 acccggacat tgcccctcac cggcttcgaa ctgctcaagg gcctcggcct gaaacacccc
      421 gccgcctgcg atctccccgt cttccccaac tggcgggagg tgccccggat cgcggcggac
      481 gtcgccggtc acctgggcgc caccgccgac gcgccgcccg gcctcctcat caccgaccac
      541 ggcatcacca catgggggga cgagcttcgg caggcccgca accgtctgga gtgcctggag
      601 tcgatctgcc agctgctcct cctcacggga accgatttcg cagaaccatg gaagagggag
      661 tgatctgatg acactgctgc aagtcatgcc agaggacgac ccgcagaacg tgctgctgcg
      721 caccgaggac cacgggcgga tcaccgaagc gctgggcgat tcctccgtga cgctgcgccg
      781 ctggcccgtg cgcggcaccg tcacccgtgg cacaagccag gaacaagtcc tctcccgcta
      841 ccggaccgag gtggacgagt tgtgcgcgca cgaagggctc ggcctcgtcg acgtcgccca
      901 actgcacccc gaggacaccg aggagtggaa ggcgcaggca gccaaggctc gttcggcctt
      961 tctcgaggag cacaggcacg gcgaggacga ggtgcgcttc ttcgcgcacg gaaacggctg
     1021 cttctacctc cacatcggcg aacgcgtcta cgcgaccgtg tgcacggcgg gcgatcttct
     1081 ctccgtacct gccggcacac gccactggtt cgacatggga ccgcgccccg aattcaccgc
     1141 gatccgcttc ttcgagaagg ccgacggatg ggtgggcgac ttcaccggcg acccgatcgg
     1201 acagcgcttc ccccgcctcg acgctcttct caaggccggg gcggcatgat gacggcggag
     1261 acgacgccgg tgcgggccgt ggtcctcgac atcgagggga ccacgggctc ggcctcccac
     1321 gtgcacgacg tgctcttccc gtacgccagg aagcgctttg ccgattggct ggcggcgcat
     1381 cgcggcgagc gcgcccacgc ggaactcctg cgagagatac gggacttcac cggcgacgcc
     1441 gcgctcgggg aggaggaggc cgtgacggcc ctggagcgct ggtccgacca ggacctgaag
     1501 gctccaccgc tgaagagggc ccagggcctg atctgggccg acggctacgc acgcggcgaa
     1561 ctggcgggcc acgtctacga cgacgtgcca tcagcgctcg ccctctggag gcacgccggc
     1621 attgactgct tcatctattc ctcgggctcg cgcgcggccc agcgcgactg gttcgcgcac
     1681 agcaatcacg gcgacctcag cggcctcgta tgcgaccact tcgacctcct cgacgcaggg
     1741 aacaagcaca atgccgagtc ctaccggaac atcgccgagg ccgttcgcac accgccgggc
     1801 gaaatcctct tcctcagcga cgagtgccgc gagctggatg ccgcagcgac ggccggctgg
     1861 cagacggtgg ccgtacggcg ccccggtgac ccccggggag tccgagtgga cggccaccgg
     1921 gtcgtctcct cgctggacga gctccggttg ctgagcggct cccggaccac ggaaaccgtc
     1981 cgccggacag cggacgtccc caactcccct gcagagaggc cgcgatgaca gacgaccccc
     2041 gactccctgc ggccgacgta ggggtgatcg gcggcagcgg attctacgag ttgctctccg
     2101 aggccgaaga gctccgggtc gacaccccgt tcggtgaacc ggccgatgcg gtcaccgtgg
     2161 ggacggccgg gggacgtcgc gtggcgttcc tgccgcgaca cggccggggg caccgtttcc
     2221 ccgcccacaa gatcaactat cgggcgaaca tgtgggcact gcgctccgtg ggcgtccgcc
     2281 agatactcgc cccctgtgcc gccgggtcac tgcgccgcga tctggggccg ggcacggtcg
     2341 tggtgccgga ccagctcgtg gaccgtacga gcggccgcgt ccagaccttc tacgacgagg
     2401 gtgccgtgca cgtctcgttc gccgacccct actacgagcc gggacgctcg gcgctcctca
     2461 aggcagctgc cgtcatgggc ggcgaagccg tcgacggcgg gacgatggtc gtcgtcgagg
     2521 ggccgaggtt ctccacccgc gccgagtccc ggtggttcgc ttcgcagggc tggtcgctgg
     2581 tgaatatgac cggtcaccct gaggccgtgc tcgctcgtga actggatatg tgctacgcgt
     2641 cgttggccct ggtgaccgac ttggatgccg gtatcggccc cgaggacggc gtcgcccagg
     2701 aggatgtctt cgcgctgttc gcccagaacg tcgaacgact gcgccgcatc gtcctccagg
     2761 ccgtacagct cctgcccgag agtgtccagg aactgccgtg cgcacgggcg acgcagggga
     2821 tgacactgcc cttcgaactg ccctgaaacg acgcgacgct cccaccccgg cccttttcct
     2881 cagaccgtga gcaggggttc ggcggtgggg gctcgcacgc cggagaagct gagcgtgcgg
     2941 tagacggcga caccgtcagc cagttccgcg cacgcccggg ccgcctccat ggccctgcgc
     3001 gtacatgagg gatcccggga gtccaggagg actccgagag tcgtgccgct gtgccccacg
     3061 gccacaccga gaccgcccac ctcacggcag atctcccgca tcggctccag cgaccgcttg
     3121 taccgcagcg gctggttcat cagcgcgctc cgggtcgcga ccctgcccac ttccaccaga
     3181 tcgtgacgcg ggatggcgtc agcgagcctg tccagcagtc gggcgtactc ataaccctgc
     3241 gctgtggagt aggacttggg tatgcggttg taggcgacgg tgtccacggc gccgccctcg
     3301 tcgatcccca ccacggtcat cgccgggagg gatcccagga ccgcgcgcag ccgcacctcc
     3361 cggtggtgga acgcgacgat ccccgggtag agcacgccgt ccgtcggttc gatccgggcc
     3421 agcaatcgct cgatccggcc gggcggcatc ggcgttgtga gggtcttcgc cacggctcgg
     3481 gccgtggcga cgaggtccgc cgaagaactg gccagcccct tgccctcggg gatcacactg
     3541 ctgacggtca gtacgcccct gacgggacgg cgctcctctt cggcgatcaa gtgcgccaac
     3601 tgcagtgctt tcttcttgtg cacgggccgt acggtgatcc cgtctgcccc cgggtcctga
     3661 cggaatgtcg ccatgctcca cctggcgacc ggcagggtca cgaggaagtc gccaccatcc
     3721 cccggcagca caccctgcag cagttcgccg aaggtgccga aggccgtgcc agtgcccgtc
     3781 agcccctgtc gcggggtcac atcgtgggag cgcttcacgt gtttcctctc ttttcctgcg
     3841 ccgcctcctc gtagccgtag ctctgcgacc gcacgagtgc gtgtgtccga gatccgccgg
     3901 acacctgccg gcggccgact cgatgtcaca tcacggtgaa ggcagctgag ggttcagggg
     3961 accgcaccag atacgggacc cggctgaagg gccatgtggg acgggacttc tcgcgtacgc
     4021 gtgaggtcag ttgacggctg ttgcgacgcc ggcatcgagg gcccacgccg gatgtcgtgg
     4081 gtggagatga aactgataat cgttctaact catccggatg cgatgaggca agccggcgtt
     4141 gcctgtgcgc attggtgtcc tcggggtcga gtggcctcgc tgcgctgccg gcggtgcgcg
     4201 gtggccaata gtggtcttga caatcatttc cacttggttg atgctcgctg acgcgaggca
     4261 gccgcccgga ttcagccgtg ccgtatcggg gtgtgcgccg ctccgggccg cgagaactgc
     4321 ggcgggatgt ctcggagttc acctcctgcg ggaggcgcgc gtcatgacgg agcagtgcag
     4381 ccggcgggga cgggacccgc aggaagaacc ccagcaggag gagccatggg cgagcagaac
     4441 cgtacgagga cagcaccctc cgccgacgac ccggcagtgg ccggggcgtg ggacctccac
     4501 ggaacccttc cgcacacgct tcccgcggac gagatcatcg ccctcaacac ccccaaggcg
     4561 gacctgcaca cgtggcgcac gtacgcctac cgggactgga cgttcgacat gccccctggc
     4621 gtcttcacgc cgggggagac gagccggatg atccacgacc ggatcctgga cgggaccatc
     4681 cccgtcggcg ggaggtgcta cggggccatg ggcgtcggcc tcggtgtcga ggcggtcgtc
     4741 gccgggctcc gcggggcgaa ggagatccac gcgatggata tcgaccccga gagcgtgcgg
     4801 gcgatgacgg atgcctacga gcggatcgtg ggcgaccggc ccggaaccct cttccacccc
     4861 cgggtttcgg acctgttcga gagcgtgccc gacggagcac ggttcgacgt gatcaccttc
     4921 aacccgcccg ccgtgcggga gacggtgagc gaggacccgg ccgtcgtgcg gaacgtgtgc
     4981 gtgggcatag gcattgtgcg gcggttcttc gaccaggtcg tgcagcgcaa cctgctggcg
     5041 aaggacggtg agatctactt catcgtctcc aacacctccg agctgcggaa catcgttgcg
     5101 tacgcgatcg aatccgggtt cttcccggag gtgatccacc atcagacgtg ggacacggac
     5161 gacgtgcaga ccttcttgtt caagttgcgc ccgagtgcag cggtctgacg gcgccgggga
     5221 tgcactcaca tatcgcggaa gcgatcaagc agcccgacct gatccgtctc gagccggatc
     5281 tgatctgcct gcgtttcgag acgatgaagg tctactcggc cttgggagcg gttcgccatc
     5341 tgctcgattc ggaggccgtg aatccgggcg acacgctcat cgacagctcc agcggcatct
     5401 acgcgcaggc cctcgcgctc gcgtgccacc gctacgggct caagtgccac atcgtgggct
     5461 ccacgaccgt ggaccggaca ctccgcgtgc aactggagat tctcggcgcc accctggaac
     5521 aggtcgagcc gtcgaagaac ctccgcctcg accaggaact gcgggtatgc cggatcgcgg
     5581 aaatcctcga gtcgaatccg tcgtaccact ggatgcggca gtaccacgac gagatccact
     5641 actacggcta ccgcgaggtc gccgacgtca tggaccggga aatccccgcg gggccggtca
     5701 ccttggtcgg cggtgtcggc tcaggggcgt cgaccggcgc catcagcacc tacctcaggg
     5761 aagccagccg ggacgtgtcc gtggtgggta tgcagccttt cggcagcgtg acgttcggtt
     5821 cggagcacgt gccggacccg gacatgatca tcgccggcat aggcagcgcc atcgagttca
     5881 agaacgtccg gcacgagctg tacgacagga tccactgggt caatttcgaa tgcgccctgt
     5941 cgggatccgt tgaactgctg cgcagcaccg ggatattcgc gggcctgtcc gctggggcgg
     6001 cgtacctgac cagtctttgg gaacggcgcg ggaacagctc gcgcacgtac gtcttcatcg
     6061 cggccgactc cggccaccgc tacgtcgagg acgcctacgc ccagcaccgc agtgccaagg
     6121 gcatcgagac cctgagaccg cacgagatcg cctccctcga cgaactgaaa cccccctggt
     6181 cggcagcttc ctggcgcgac atatcccagc cggcgcacgg cagttgacgc cacggccccg
     6241 caaagaacct ggccggcccc tccaacggtc ggcctccggc tcacagagca gcagcatcac
     6301 atccaccact cgacgagaga accgagaatg ccctacccga agccgcacac tgtcgcggaa
     6361 ctgaccgagg gaatactgga gggggcctat ggcccggatc cgaaggacat aaccgtcacc
     6421 agcgccttct ggctctatca cacgacgcgg ctggcgggcg gcgacgtcac ttaccacaac
     6481 cactacctcc tgctgcgcgt gggagagagc ttcggcgcct gctccttcga agcgggcgag
     6541 ctgagccccg agttctgcga gaacgcctcc ggtttcactc tggagacgct cctacgcaac
     6601 gagtccgcct ccgtgcgcat cgccgcactg gacgcctatc tctcccgggt tcgccagcac
     6661 cgggaggccg gtgaagccga gccggtcacg ctgcccacgg gaacgccgga gatacgggcg
     6721 agggcgcggg acgccgccat cgccggactc ctcgaccttg agccgggcgc caaggtggct
     6781 ctgatcggtg tggtgaatcc actgatcgaa gcgatacgtg accgaggtgg tgtgtgtctg
     6841 ccctgtgacc tgaatctgcg caccacgcag tggggtgagc cggtctcgga cgacatgacc
     6901 gaagtcctcg agcaggcgga tgccgtggtg gccaccggaa tgaccctcgg caacggcacg
     6961 ttcgacctga ttctcgagca ctgcaggcag aacgccctgc cgctcgtggt ctacgcgcag
     7021 tccggcagcg ccgtcgcccg cgcgttcctg tccagcggcg tctccgcgct gtcggccgag
     7081 gccttcccct tctcgcagtt cagcgcggac gcgaccgtcc tgtaccgcta ccgggccgac
     7141 agctctgcgg cggcactcga ggaggcatct tgagcaacgg cgccgggact tcacagatga
     7201 agcgcgacga cccggacacc ggtgagcagc ttccgagcga cctgaacatg acgcgcacgc
     7261 tgtggccgat actgctggcc tcagcggtcg ggctgctgcc cttcaccatc ttcagcacgt
     7321 acctggtacc gatcgccggc gagtccggaa gcagcgtcgc agcgatgggc ggactccgtg
     7381 ggctcggggg cctcgcggcc ctcttggtcg gtacggcact ggcaccgctg atcgaccggg
     7441 tccccaagga gtgggccgct gccggcggac tcggagtgct ggcggtctcg gccgctctcg
     7501 gagcgagcgg cgaatacgtc cttctcgtgg cgttctgcct gctcgtcggg gctgggacag
     7561 ccgtactcaa tccggctctg acggcggcgg cagccgaccg gttcggctcc gggaaggcgg
     7621 ccagcagggc ggcgacgctg gtcacggcca cccagtccat gacggcgatg ctggcggcgc
     7681 ccgtgatcgc gctgcccgcg gtgttctggg ggtgggaggg agaccttctc gcggtcacag
     7741 tcgtctcgct gctgctcgcg gccatcctgc tctcacggcg cgggcattcc gttgtggagg
     7801 aagaagcggc cgacagcggc gagaagttga gctacttcgc ctccttcaag gcgctcgccg
     7861 cggtgcgcgg tgccgtgccg ctgctgctga tatcccttct ccgcaccgca gtgttcatgg
     7921 ggtacctggc atatctggcc gcgtactacg acagccgctt ccaactcgac cccggactct
     7981 tctcgttcgt ctggacgctc agcggtgctt cgttcttcgt gagcaacctc ctcacgggac
     8041 ggctgacgaa ctccgctcag ccccgggtgc gtactgagca cctgctgctc ctcggccttg
     8101 tcgcggccat ggcctccgtc gtcggtttct acttcacgca ctggcttccg ctggctcttg
     8161 tgctcacttc gctccacgca gcgagtcacg cggtcgtcgc cgcgtgtgcg gtgagcctgc
     8221 tggtgaggcg ctgcggggcg ctgcgcggat ccgcgttgag catcaacgct gcggggatga
     8281 gcctcggcgt cttcgtcggc gcttccctgg gcggcgccgg gctcggcctt gccggctatc
     8341 ccggaatcgc tctggtcttc ggggcgctca cagcggtggc actgggggcg gccttcctgg
     8401 tctcgcgtct ctccggcgac gaactcaccg gcgaggacgg cacggagaac cccgattcgt
     8461 ccgacacgtc cacgacctcg tgaccggcct cacgacgaac acgtcgtcca ccatccgttg
     8521 cggaaaggag tgcgtatgtg cccgtcagca tcatcggcgc cgacggtgag cagcgattcc
     8581 cgcaccccgg aggggaaggt gggccaggct tccggcgccc gtggttccgg gtcctctgtc
     8641 tcacgcatga ggctgacgac gacgtgcgtc gtcctcctcg ctctgctgct ggtgtcggtc
     8701 gtcgtcgcca ttggtctcgg gactgcggtg atcacgcccc ccgacaccgc ccggtacctg
     8761 tgggcggctc tgagcggcgg gaagatcggc gcgagcgaga cgacgacgta tcagatcgtc
     8821 tgggagatcc gcactccgcg cgtgctgctt gccgcactcg tcggggcggg gctgagcacc
     8881 atcggggtcg ccgtccaggc gatggtgcgc aacgcgctgg cggacccgta cgtcctgggg
     8941 gtctcctccg gagcgtccgt cggtgcggtc ggcgtcaccg tcacgggtgg gcttgcgggg
     9001 ctgggggtct acgccatgtc agcgggcgcg ttcatggggg ctctggcggc atccgccctg
     9061 gtgtacacgg ctgccgtaag ccgggccggg atgtcaccgc tgcgcctcat actgaccggc
     9121 gtcgccatgg cgctcggctt ccaggccgtg atgagcgtga tcatctactt ggtccctaac
     9181 agcgaggcca ccagcacggt tctgtactgg accatgggga gcttcggcgc cgcgacatgg
     9241 tcagcgctgc ccgccgtggc cgccgcggtg ctgctcggcc tggtcgtgct gcggcgctac
     9301 agccgcgccc tggacgtgat ggcgctcggc gacgagaccg cggcgagcct gggcgtcgac
     9361 cccgaccggc accgtaagca acttctggtc ctcgtctcgc tcgtgaccgg tgccatggtc
     9421 gccgtgagcg gtgccatcag cttcgtcggc ctggtcatgc cccacttggt tcgcatggtc
     9481 gtcgggtcca cgcacgcgcg cgtcctcgcc gtcagcccgc tcgtcggagc cgtcttcatg
     9541 gtgtgggtgg acctagtcgc ccggacgctc gtcgccccgc gggaactgcc cctcggcgtc
     9601 atcaccgcac tggtcggcgt cccggtgttc gtcacgctga tgcgccgcaa ggcctacatg
     9661 ttcggaggcc gttgacatgg acctcaccct cgatcagctc tccgtcgtca ccgatggcaa
     9721 gaagctcctg agcgacctct cgctgaacgt gccggacggc cggtgcgtcg gcctcgtcgg
     9781 acccaacggc agcggcaagt ccaccgcgct gaggtgcatc taccgggccc tgcgtccgag
     9841 ttccggcacc gtgcggatcg gtgaggagga actctcccgt ctgaggatgc ggcgaagcgc
     9901 ccaactcgtc gccgccctcg cccaggacgg agaggtcgaa ctcgacttca ccgtcgagga
     9961 agtcgtcgct ctgggccgca cgccccacat ccggggcaac cacgtgctca gtgccaggga
    10021 gcgggagctg tgcgagcggg ccatggagca gctcgacatc tcccacctcg cccggcgggg
    10081 cgtactgacg ctctcgggag gcgagcgtca acgcgtcctc gtggcccgtg cgctcgtcca
    10141 ggagcccaag atcctcgtcc tcgacgagcc gaccaaccac ctcgacgtac gtcatcaggt
    10201 ggagctgctg tcgctgctgc gcagcaccgg cctgaccacc ttggtcgtgc tgcacgacct
    10261 caacctcgcc gcagcggcct gcgaccagct cggcgtgctc tccgaaggcc gcctggtcgc
    10321 ctccggaact ccggagaagg tcctgacgcc ggaattggtt cacgacgtct tcggcgtccg
    10381 caccaccgtc gtctgccacc cgctgacggg cgatccgcaa ctgctgtatt ccctcaccct
    10441 cacccctgca tcaaagaacg gaagtgacac gtcatgcacg ccacccggcc actgaactcc
    10501 gcacggcgac gcgccgtcat gggatcgacc gcggctgtcg cactcctgct cacgggatgc
    10561 ggtgccgatg tcgcgaccga cgggaagaag tccgagaagg ccaccgtcaa gaggtgcggt
    10621 gagccggtcg aatacaccac ccctcagcgc acggtcgcct acgagggcgg cagcgccgac
    10681 aagctcttca gcctcggact gaccgaccac gtgtacggct acgtgatgcc accggcgaac
    10741 cctcccgtga aggagtcgcc gtgggcgtcc gaatacgcca aggtgaagaa gctcagcgac
    10801 gatctcctga acaaggaagt cgtcgtcgat gcaaaggccg acttcgtggt ggccggctgg
    10861 aactccggct tcagcgacca gcgcggcatc acacccgaga tcctggacaa gctcaagatc
    10921 cagagcttca tgcacaccga aagctgctac aactacccga agcacccgga gaagaagaag
    10981 cctttcgaag ccctctacac cgacctggag cggctcggga agatattcaa ggtggaggaa
    11041 aaggcgacga aggtcgtcga cgacctcaag cagcgtgaga aagcggtgga ggcaaaggcg
    11101 cccaagggca gtccggtacc ggtcttcctc tacgactcgg gcacggacca gcccttcacc
    11161 gcggggaacc aggtcccgcc caacgacatc atcaagaagg ccggtgggaa gaacgtcttc
    11221 tcgaacctcg accaccgctg gacacaggtg aactgggaga gcgtcaccaa gtccgagccc
    11281 gaggtcatcg tgatcctcga ctacggggac aagccggcca agaagaagat cgatttcctc
    11341 aagaagtcac ggcagaccaa ggagttgcca gccgtgaaga acaacaactt cttcatcctc
    11401 gactacaacg aaggcatcag cggcccccgc aacatcgacg gcctggagaa gttcggcaag
    11461 tacgtgcgga aactggaacg ctgaagcacg cagcagctat tgtgtgaaaa aactcggtat
    11521 gcatggctct gtgcgggatg cgtcggagga ggctgacagg cggaacgtga tccgcgagga
    11581 ggccgacatg gacagacgtg ggggttggag cagcaggcaa ggtttcggtg agggggcggg
    11641 ccgatgtcac ggccagatac gcagaggggg gcatgcggag cgggccggcc ttgctgcgga
    11701 tttggcgggg gagttcgggg cggagttggt gcgggctttg cgtgcggggc tggctccggg
    11761 ccgggccggt gcatacggtt cgcgtgggcc gtcgcagctg agttggtacg cgttcgccgt
    11821 ggactacgct caggcgcact ggttggggcg ggcggcgcac acccggcggg agaacagcga
    11881 ggcgctggcg gccattaccc gggcgatgtt gcttgacctg ccgggtcgcc ccgaggagtc
    11941 gctcctgcac cgttcgctgc agggatgggc attcgtcgta ctcgggcccc aggaaggcga
    12001 agttcccgta caggcgcggt tggtactgga ctgggtagcg aaggcgtccc ggccgttgat
    12061 cgacctgcat gacccggcgg tggcccgcgg tgtgcttgat gcactgcgcc gcaagcgcga
    12121 cggcacggcc gcggcccggg agacatggcg acgcaaacgg aaggtgctgg tgagcgcctt
    12181 gtactacgcc gtcgaacagg gtgagttggg tagtcatccg ctcgacaaca tcaggggtgg
    12241 agtctcgcgg caggtaacca aggtcgatcc tcgtgttgtc gtcaaccctc agcaggcgcg
    12301 cacactgatc accgccgtca cttacgtcgg cacctatcac cgggcacgtg gccgacggct
    12361 cgtcggcttc ttcgcgggca tgtattacgc cggactgcgt ccggaagagg cagcgggggt
    12421 ggtggtgacc gactgcgtgc tgcccaccag tggttggggc cggctggtcg tcaaccgggc
    12481 cctgccgcag gtgggcaaga agtggactga cagcgggcgc cgccacgacc agcgggggct
    12541 gaagaaccgc ccggcaggtg agaccagggt cgtgcccctt cctccgcacc tcgttgcctt
    12601 gtggcgcgag agcatcaaca ccttcggggt cgcagacgac ggccgcctgt tcttcaccga
    12661 gcgcggcgac atcatcggct ccacctcgta ctacagggcc tggagcgaag cccgcacgct
    12721 cgcactaccg ccgcaacttg tggcgtcccc gctcgccgcg aagccctacg atctacggca
    12781 ctccgccctg tccacctggc tgtgctcagg agcagatcca gcggaggtgg cccagcgcgc
    12841 cggcaacagc atcgacgtcc tcctcacgcg ctacgcgaag tgcctctacg acaggcaatc
    12901 catcaccaac cagcgcatcg agcacctcct acgcgcctac gacccgcccg ctccggacga
    12961 cgaaacagct acggcttcgc ctgagcagtg acccgccaaa ccgtgcacgt tttccgcaga
    13021 gccgccgaca atgcactggt cgagccactg atgcctcttt gtgcggctga cgcgtaatcc
    13081 tcgcgaccgc cgaagggtga ctgcgttgtg ccgacgccat cgagcactct gagctggact
    13141 gatgccacaa gtaaacatcg ccaccggggc ggacctggcg cgtgccgcca aaaggcaaac
    13201 ggtccaagca ccgtttgcct tttgacatga acgcaatagg tcctgacctg tatttctgct
    13261 gctcaggacc cttgatcgga agtacccccg gcaggattcg aacctgcgca cacggctccg
    13321 gagcgttcga ttcccagtga ttcgcgcagg tcagcgtctt ctctgacggg cagtcgagcc
    13381 agtggcgtca gaaatgcgtc aagtgctccg gcggaggacc tgacgctccg tggactgaag
    13441 gggcctcggg tcaggtctct tcgcaaagga gtttgccctg cgccccgtgg cccggaaaca
    13501 atgtctgtct gcgtgacgtt ggtcgcggag gcgggattgc gaggggtgac ggggctgaag
    13561 ctgttcacgg tgaacggtgg cgtggcggag gtctcgtccc gccttgcggg gcgcgagcgg
    13621 gagttgcatc agctggtcgg ggccaacctg gagaccatgc tgggggtgcg gccgttggcg
    13681 agtgagtaca gcaccgggcc ggtccacggc ggtcggatcg acacgctggg gatcgatgag
    13741 ggcggggctc cggtcgttgt cgagtacaag cgcggtgtgg atgccggcgt gatcaaccag
    13801 ggcttgtact atctgtcgtg gctggtcgat catcgggcgg agttcgaagc tctggtccgc
    13861 ggccgtctcg ggccgactgc ggcaggccag gtgttgtgga gcgcgcccag gctgatctgt
    13921 atcgcggcgg gcttcagccg ctacgacgtg cacgccgtgc gtgagcacag gcgctccatc
    13981 gacctggtca gctaccgctt cctgggcagc gatcacttcg ccttggagac ggtggcgtcc
    14041 gtcggcaggc aggcggcccc gaccagagca gctggcgttc ccgatgcggg aggcgaagcg
    14101 cagggccgcc cggccggcgg ttcgctggcg gagctgcggg aggccgtggg cgaggttctg
    14161 tcgggacttg gcgatgacgt gaagcggata gagacccaga cctaccgggc ctaccggaga
    14221 acgcagcatt tcgcgtgcgt gtgccctccg caggagacca agctgctggt ctacctcaag
    14281 gccaacccga agaaggtcga cctcatcccg gacttcaccc gagatgtgac cgagcgcggc
    14341 caccatggca cgggcaatct cgaggtggcg ctgcgaacgg agcgggatct ggaacgcgcc
    14401 gacgagctgt tccgcctcag ttacgacgtg tcgtaactcg gcagcgctcg cgctcgggtg
    14461 cggcggtcgc gcgcttgtgt gtggagttgt gggttgtgga gtgttggcgg cctttcgact
    14521 cgggagcagt gggtggcggt ggacttccat gatgcggcgg atccccggtt tggctaaccg
    14581 gggatccgcg gttatatacg ggcgctgctc ctgcaccacg ctgcgcggta acgcaaagcc
    14641 cgctgtgagc cgtgttcttg ccgacgaggc ggtctgaaga caccggttga aatacgcgcg
    14701 tttcgctttt ccgggagcgt tgctgggaat tgctgtgagc ggcgatttcg ccaggagtcg
    14761 cgatcactgg agactcaccg gtcccagcaa gcccgtggcg cagaagtccg aggctgaaca
    14821 gcgtcgttga aagcacgcga tgggagctgt cttaccagga gatgacgggt tgcggcatgc
    14881 tgggtacatg agcaggtgcg cggcagccag gatctccgtg cttccggagt cgctcggcga
    14941 cttggccggg ccgacctccg ggaatgtggt cctgccccgg catatcgact ggggaccgca
    15001 ctacgagtac gacctcgccg acgaggccga tctgattctc atgtacgagc gggtcatccg
    15061 cgaggcccag tcagcggccg acctacgctc ctacctgagc gctgacctgt tgctccggca
    15121 ctgggggaat ctcttcctgc cgtctgcagt ccgcgtggcc tggcagacac gcttccccga
    15181 gctggggccc acggtggccg cagcgtagtg caggagttgc accgccggct gatccgcgct
    15241 ggctcgacgc gctgggtgac gacttcgatg agcggccatc gctagggtcg atgacatgac
    15301 gtacacgccg cgccggccgg tctctgaact ccccttcggc gggagcgaca tcatcctgcg
    15361 ctaccacctt gagcacccgg cggtcccctt cgatttcgag gagaccctgg agacgtggtc
    15421 cgtcggcatc ttccggtatc acggagagga cgaggcgtgt ccgaactgct cggaggagca
    15481 ggcgtgcgag ttctacgaga gcggcactcc ggtcggggac atgagcttcg tccggatccg
    15541 cgactacacc tccgaccccg cttgggaggc ggccgactcc cagtcgggag acatcgagaa
    15601 ggtcgtcgcg gtgtgtaccg acccggccta ctccatgacc cccggcctgc attggtcgga
    15661 ggacttcgag aggaccattg agatgccctt cggcgacctc ctcatcatga accgggtcca
    15721 catcgccccc gagtggcgag gcttcggcat cggcgcactg gccgcggccg aggcaatccg
    15781 gcgcctgcgc ggcggatgct gcgcagtggc gtgtgaacca gcgccgacgg accgcgagtt
    15841 cggagatgac gagaccgctt tcgccaaggc tcgaaccaag atcgccaggg tgtgggaatc
    15901 ggtgggcttc cagccgttca agaacggcat ctacctcctc gactctgcca tgcagcaccc
    15961 ggaagactgc aggattgcct ggcaggagca cttcgcccgg tagtcgaggc aacctcctgc
    16021 gtgaggttgg gtgtgccgct gcccgggttt tccgtcagcg ccggtttcca cgtgaggcgt
    16081 gaagtgcggg cggcgcgtgg atcgctggtt tcgccgaagg cgggcggggg cgttcagtgg
    16141 ttgccgtggt gctgggtggt gctcgaagtc ggcagcgggc ttgctgggct gtgaggtcgg
    16201 ctagggcgcg gcgggtgccg gtggcgagtt ggtgggggct gttggcgggg tcttcggcga
    16261 aggcgcggat acggatggcg gttcggtggg cgccgaggag gagtgcgcgc tggaggatct
    16321 gttctgccca gtgttcgggt gagccggcag gctgggagag gcgggcgagc acatcctccg
    16381 ggcgtgcgtt ggagggggcg aggagtccat ggtgctgtgc ttcccacagc accgtgatcg
    16441 ggtcgatgac ctcaccgcgg agggcgaggg cggtcaggca ttggtagagc tgtccgtgca
    16501 gtggcagggc gaagtcctcg gcgcgcaggg gcagttcttt gaggtcgcct gctcggtcgg
    16561 tagcggtcgc gaggaacagg cgttcttctt ccagcgcttc ctcggtcctc tcgggcggcg
    16621 gatccgccgg gaggggtgtg cggggaaggg agccggggtg cggcctggtc tggccggcca
    16681 gctcatcaac gaaccgagcg aggacaccgg cctgttcggc gaccgcggcg acggggtcgg
    16741 gcagggtggt gtcggtggcc agctgttcca ggcgcatggc gtgttcgcgc agggtgcgtc
    16801 gtgcgtggtc ggcgcggatc atctgtgcgt aggacgcagc gtgttgtggc cgtgggcagg
    16861 ctccgatgca tgtgtggagg taggcggtgc tcacgcccgg agcttcatcg acggcgcgcg
    16921 cgaggacggc gttgatccac gccggctcct tgcggtgcag ctctggctcc ggtggcgtga
    16981 gggtgcgcat tgccgcgtac accgcccggt gggatgcggc ctggaagtgt tcaggcagca
    17041 gggcctcggt ccgagccagc tgctcggggt cgaggaggag cgcgccaagg agggcttgct
    17101 cggcatagtg cacgggcggc tctggcgcgg gttctacgtc gaagtcctcc tcgtctgtct
    17161 cgggggtgtg gggcat
//
