LOCUS       reptomyces_RBGC_425811 16340 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_425811
VERSION     Streptomyces_RBGC_425811
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_002155735.1
  ORGANISM  GCF_002155735.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..501)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058324"
                     /pseudo=False
                     /translation="MAFLEDLFMSSRPAWLVGCVLAQALLLTSCTSDDNSASDPTASPT
                     TTRRSTELETEKKLTAEVQSALDAVTDQGGSMIESGVERVSDGAHTRPGLAKDGTYKVA
                     VVCAGKGDTEIVFTPTTAGPKKLVHCDGTVVFQRFAAQDSLRLDIQGQPGATGMIAWRI
                     NEV*"
     CDS             complement(475..1130)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058325"
                     /pseudo=False
                     /translation="MGIGARRTVIASTTALLLCLGTTGTASAEDVPVFSANGSDQAAGA
                     DVVDAADTVEINEREWEGDVTEMVPEPFNCSGPETWIEIKKKKKYHVPSWWNGTSYKDG
                     PGGTMTVSVIKSGTISAEVTGTIEAEANLVIAAAKSSVSYKISGSVTVTTGHTYTRNIP
                     ERKYGHLQYGSWGYKVSWEKYRRKGNGCNGATLIDSGTATLPTRETGWRFWKTSS*"
     CDS             2190..4624
                     /protein_domains="PF13625"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058326"
                     /pseudo=False
                     /translation="MKSRSTLVTWLSELDGSRLARVLANRKDAASSPEPRSVGELADRL
                     QRPGSVALVLPQLTLPCLQATEALAVLGARATRDSLAELLGSRSPTAVHALDATLEALS
                     DRALVWQDGNEALRMPTPLRQAWSTPLGLDAPLGELLAGTTSEELRGMLAVLGIKPPGT
                     KQQRLSALVEHHSDAERVAALVAGAPAATRKLLERSARSTPRQSLFVVFGTPGRDLQPG
                     ARWALDRGLLLQDRHRYGPARMPVEVALALRGPDWHAPFEPLPPVTQLVPITSSEVERE
                     AAVAATAFAAHAASVLSACATAPPTRLKSGGIGARELARLGKAAQADDAVVRIALETAY
                     AAGLLARDGDRVPPTEAYDVWAEQEPAEQLAVLLRAWRDLPLTPTRARDEDNKALPALA
                     GAPDCGGCLQARHGLLIAAAGLPAGQGAKVASELGPLVAWHRPLADDASPQDTAPFSTV
                     IREGELLGVLARGALSPLGAHLAAHTDEELDITARRLLPPATTTARIGADLTAVVTGTP
                     SARLAALLDSTADRETSGTASVWRFSAGSIRRALDAGRTPDDITADLAAGSATALPQPL
                     TYLIADTARGHGRVRIAPAACVIHGDEPALLAELAAHRALSKLALRRLAPTVLVSGSPP
                     VTTLAALRAAGYAPVAETAGGTVRIEKRLPQRAAAAVPPPRGNVGRRGPRTTATHASEM
                     LIDAGTDVDVLADRLLKAPPNAPEPDPFGSGVPFATDTEEIVAGYAKHLSYSDVRQVAH
                     AIDAGAAITVEYIATSGSRTVRTLSDLELDPPYLNAWCHLREAERVFTLSRIHGVMPA*
                     "
     CDS             4720..4934
                     /protein_domains="PF09957"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058327"
                     /pseudo=False
                     /translation="MSRTVIDLDDDLVADVAKALGTNTKKETVNTALREVLDSRRRALA
                     LARLRAAAGDGAFDLELFENKEIYRR*"
     CDS             4932..5353
                     /protein_domains="PF01850"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058328"
                     /pseudo=False
                     /translation="VNAAQFLIDTSAFARFMRGEAEQYGWDQAAAAGLIATCPITELEF
                     FYSARSAADRARGIEDMRLIFGWVPVDDRAYDRAWQVQEALTKQGKHRSAGPVDLVVAA
                     TAELQGLTLLHRDHDFECIAAVTGQALQWYGPEHGK*"
     CDS             complement(5599..5828)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MAWANEPRAASIVVGFVIPWECVSAGRSDAASATTPSAGEMPPRS
                     RTSYSKTSAGRSPKPYGTPKPPVDKNQDNEG"
     CDS             complement(6189..6463)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058329"
                     /pseudo=False
                     /translation="MTGRRVVLIEPRSTEAAGAPELAAVRFIALLPEGWDYEPEFAGER
                     FTVRLRWPTDPDPETETDPDLGRALDRIFTDSSLRAWRWTDITHHT*"
     CDS             complement(6461..9156)
                     /protein_domains="PF00069"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058330"
                     /pseudo=False
                     /translation="MDLRYVTYCQAGNAFYEDPATAAATTEPADVVAEPPAGWTRTVNS
                     DWVVLTPPHTELPGQGWKIHVSATRDNADHILDVVRAYCVRERLTFKYIRSAKVLSRRN
                     SKYGDRGASGKFITVYPLDEPQLERVLVELDAEIGGEPGPYILSDLRWRSGPLYVRYGG
                     FVARLGRDAKGDPVHCIEDPDGRLVPDVRGPGFRPPAWVTLPDCLAESLAARNASTMGD
                     FPFRAVRALHFSNGGGVYEAADLRQGPGTGASASVLLKEARPLAGLDEEGADAVARLER
                     ERWALERLAGLDCVPPLIDYRKGREHYFLAREFVPGASLHTRIHESNPLLNPDADASPG
                     SFAAYTSWALSVIDQIDAGVRAMHARGVVFGDLHPNNVLVRPDGTIAFIDLETATPVDD
                     EAPQAIGAPGFRAPAGYVGAAVDRYALGCLRLAVFLPLTVVVGWGREKTQQLIALVTEN
                     FPVPADFAERVAADLAGPEGGEATEAAKADAADAHAETDADTEADTDADTEADTEAAVS
                     AERAAAPVWPETLTPADWPSLRASLAAGILATATPDREDRLFPGDIAQFTDPGGGLDLA
                     HGAAGVLWALGGAGTEIPAAHVDWLTERVRRWADPRPGFYDGLHGIAYALDALGRTVEA
                     REVLDRALALPLDDLDGSLFAGLPGIGLSLLHFGHLDAAERLAELVADRTPGGYAARPR
                     PGLLYGATGAALFLLRLYEKTGDRKLLHGAVEALRHDLAELSAGPGISRMPYLAVGGAG
                     VAMVVSDVLPHLPFPEPELNDSFPLLQSSVAALYQAQAGLFQGRAGATLALRHLRDRTP
                     EPEPGSEPKSVLEPKSETEAAVRRHLVAFGWHAIPYAGHPAFLGDQTLRLSTDLATGTA
                     GVLLALDEALGSGGSLPFFPSSRRRPS*"
     CDS             complement(9220..10886)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058331"
                     /pseudo=False
                     /translation="MSSTPAGAVLLAPERLARPRLAPDVVVHEPAEPGAPWVVQRGSHQ
                     YFRLQEDLARLVRAVDGVRDHDDLADALGAPWTQADVGSAVRTLAGAKVLDDGVPKKDR
                     SSWFRFVPPLTLQFTLLKPDRLLARLAPLVEAAANRKAALVASAVTIGGLLALALQTAD
                     LQGALGRPFAPLLYLCVIGAVLATTAVHEIGHGAVLTYYGGRPTRMGMMLFYMSPAFFC
                     DVSDGWRLPRKEQRVRVALAGIATQTVIAGGAALATLFMGDSAARDGVLVYAVVTYLSG
                     VLNLLPFVKLDGYIALMSHLDIPHLRDRAMTDARRWLARLLAGGTGYRRELPGVRWAVP
                     FGLLCMTFPLYIVAGAITLWSDSLQRLGALGALLVLCGIGYFLHHLARGVRRFAREART
                     AGGLPWRLGAVLALAAAAIAVLGQLVQVPYTVNGGYTTAKDGRITLLLPPSTDRSLIEA
                     GAPVRLYRAGIATREQTGAATVAVDGADGTDAMAPLSALIPVRSEALPTPALGLPLETR
                     DGQGRTPADVSGAAQLDAGSRPGWEWLYTKYVAPAWRW*"
     CDS             complement(10996..11168)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MTSSDLVRSCLATSVVVRCCLTTSVVVRCCLTTSDVVRCRLPSSN
                     VRPSCPTASVAV"
     CDS             complement(11187..11929)
                     /protein_domains="PF12730"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058332"
                     /pseudo=False
                     /translation="MRNLLAGEWAKAWTGRGWLILAGCGVLMSLLGALGYASQGATAID
                     EGTMGRAAVTDDIVRSWFMMSLFTSLFGAVFVSREYTSGAIGRSVLMSGGRTRLLAAKV
                     LIATAVGALAALFTAALSLASAWGALAANGTEPAWHGETWLILLGVFAVNTLAAPWGAL
                     IGWIVRHQVGAVVTVVALTLVVDPAVQVLVPDAGKYLMTIAQSSVYRDMKPELLSTPLA
                     LLVIAGWLAAAGLLARKLFTARDVV*"
     CDS             complement(11923..12704)
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058333"
                     /pseudo=False
                     /translation="LSTANASSTGAAPVVALRGLTKRFGEVTAVDDLTYEVQPGRIVGL
                     LGRNGAGKTTSLRMLLGLCRPTSGEAAVFGRPYAELPHAARRVGVSMDAVGPLPGASAR
                     RELTIWARTLGLPKQRVEEVLELVGLADGAASRPVKGYSTGMKQRLALATALLPDPELL
                     VLDEPANGLDPDGIRWLRGLLRGLADEGRTVLVSSHLLSEVEQTVDDVVIIQSSLRYAG
                     PLDGLVGAGEGERLEDRFFSLVGTATTASSAVGGQNHA*"
     CDS             complement(12702..12898)
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_5058334"
                     /pseudo=False
                     /translation="MANSRDKAAAENKNLAFACALIPLGMAVATTQLTGGLEIFVMAGL
                     GVVMLSCLVRIGANLRKARR*"
     CDS             complement(13142..13296)
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_5058335"
                     /pseudo=False
                     /translation="MKDTVTQEPNGFDASLELGMQELEAMEAPGFWSGFKTGVVISTVA
                     SAVIAT*"
     CDS             complement(13397..13569)
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_5058336"
                     /pseudo=False
                     /translation="MQENFDNNNFSSDLELGMQELEAMEAPGWWTAGGVVVGATVVSAV
                     GVSTGVAVSIIT*"
     CDS             complement(13650..14938)
                     /protein_domains="PF00465"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058337"
                     /pseudo=False
                     /translation="MSYGRGGPTRALIGPDALTAWLPDGAGRTAALLVDSAVATAGITA
                     LVRDRLGRAHWRTTQTPLTTGPGDLGTAAAIAEGLADKLAGIGLVVAIGGGSVLDQAKI
                     AALLRANPVAYTRLTVPQRGGLMGLPGEVTRTVPLLAVPTTLGTGSELSAVACLAYPQG
                     KRLILGGVLRPEAALLDPSATATLPRELVVEGVLEALFRAVSPYAGDHRDDRRTEDRLT
                     ETVARRLVQLGYEAVREEKPGDALRLDIAKLSGLTHGEWLHQGRDPYAVKGWLIANEMS
                     SALGVRKMTAVAALLPHLWRAVLDGEPRLGSAPRLHRMWAGLRDAAPRDRAQALPADPA
                     DGIEALMDDWRVGRRLTAGGPGQIEALAERTVRAWGAGLPMLGGLRAEDVRRLLDAALG
                     ATKTSTVHPTSTKHTARTAHTARTAHPAHT*"
     CDS             complement(14936..16260)
                     /protein_domains="PF00202"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058338"
                     /pseudo=False
                     /translation="MSPVHTKSTKSTKSTKHALWPSLLAPALHGSDALCAVSAHGVRVR
                     YADGSELLDASSGLWNTNIGYGNEAIAQAAAEALREASYLSVFRYENSYARAAAAALVE
                     LCGADTYGRVLFSTSGGAANDLVMKLARHYHALRGEDRRKLVVGLRGSYHGLTYGSFAL
                     TGEDLGQQVYGVDQRLIRHVDPNDPLGIRTLMERQGAMVAAVVVEPVLGSGAVPLTEEY
                     VEELLRLREEYGFLLVADEVATGFGRTGDFFASQRWSARPDLLVTSKGLTNGTSAAAAV
                     IASHTVADAFDTAGAMLTHGETQAGTPATCAAILATIAEMRRLDAVALGRALGERLDAE
                     LSGLVDEHPWVTGTTGLGCFRSLRLTTPDGEPLPQARVPELVAAIRTAGAIVHPGVHGI
                     QLFPALTYTDAELTELMDRIRAGLALFTGQSVPAEAHAEVPA*"
     CDS             complement(16258..16340)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5058339"
                     /pseudo=False
                     /translation="ARHPLPAVGSRHHDVLLEVLLETEVTP*"
ORIGIN
        1 tcagacctcg ttgatgcgcc aggcgatcat gcctgttgcg ccgggctgcc cctgaatatc
       61 cagtcggaga gagtcctggg ctgcgaagcg ttggaacacc acggtcccgt cgcagtgaac
      121 cagcttcttc ggacccgcgg tggtcggggt gaagactatc tccgtgtccc ctttgccagc
      181 gcatacgaca gccaccttgt atgtgccgtc tttggccaag ccgggccgtg tgtgggctcc
      241 gtcggatacc cgctcaacgc cggactcaat catcgagcca ccctggtccg tgacggcgtc
      301 aagtgccgac tggacctcag ccgtgagttt cttctctgtc tccagctcgg tgctgcgacg
      361 ggtagtggtc ggtgaggcgg tgggatcgga tgcggagttg tcatccgacg tgcaagatgt
      421 cagcaggagg gcctgtgcca agacgcagcc gacgagccac gcgggccggg aactcatgaa
      481 gaggtcttcc agaaacgcca tccggtctcc ctggtgggga gcgtcgccgt gccgctgtcg
      541 atcagcgtcg ccccattgca gccgttccct ttacgccggt acttctccca cgagaccttg
      601 tagccccacg agccatactg caagtgaccg tatttgcgct cggggatgtt gcgcgtatag
      661 gtgtgccccg tcgtgaccgt gacacttccg gagatcttgt aactgacaga cgacttggcc
      721 gccgcgataa caagattggc ttcggcctcg atcgtgccgg tcacctcagc cgaaatggtc
      781 cccgatttga tcacgctgac ggtcatggtc ccgcccgggc cgtccttgta gctggtgccg
      841 ttccaccatg acggaacgtg gtacttcttt ttcttcttga tctctatcca tgtctccggg
      901 cccgagcagt tgaacggctc tggaaccatt tcggtaacgt cgccctccca ctcgcgttca
      961 ttgatctcga cagtgtccgc cgcatcaacg acgtccgcac ccgcggcctg gtcagagccg
     1021 ttcgcggaaa ataccggtac gtcctccgcg cttgccgtcc ccgtcgttcc aagacaaagg
     1081 agcaaggccg tagtggacgc aatgactgtt cggcgcgcgc cgatacccat gagtgtcccc
     1141 ctggtcgcag atcgccatgg tcggcgatcc gatgcctgga cactaaggga tcatcatgct
     1201 cacctcaatg aagtgacctc ttccctgagg gtaatttgag ggtcacgtcg gatctgtcga
     1261 gtgttgcagt aggcgaacgt gccggcctcc gatcctgtag gcgtcgcccc cggcgggcac
     1321 accgccgaat cctgcggtac agcagcgcag tacaacaacc acggcaagcg tcagcgtcac
     1381 ccctcggctg tcgtggccct tcccgcagcc tgtatgagct ccaatgaccg atctctgtag
     1441 agctacggat cagaaggccg cgacggaagc acgcgccggc agagacgatg gtggcatgcg
     1501 ctacttcaac cagaccggtt ggctcgccat cttcacctgc acggacacga tgatcgggcg
     1561 aaccgtagac gtggacgccg ggacgacgct acgggcgtgg ccctcgttgt cgatccaaag
     1621 cagggcatgc ggcggccggt cacggagtac ccagacttct cccacctggt gaggagtgaa
     1681 acagcctccc ccgcgtcgcc gtctcagttt ccgtctcatt cagcaccgtt cacggccgtt
     1741 cagagaaggc cgcccgtcag gctcgccgag caggccagcc gcccatgaac gcaggtgaac
     1801 ggccccgcac acaccccgcc accccaccac cacagttgga aagcgtgttg ggttcacacc
     1861 ctcacgagtt cgaatctcgt atcctccgcc agtgcctcac cgggcacgat atcgaagggc
     1921 cccaccgctc gcggtggggc ccttcgctgt gcgctggttg cagttttggt tgcgtttata
     1981 tccgcccatt aaggatgttt cggcagcggg tagccagtat cttctcctgc cgccgggctg
     2041 ggcccgcggg acgagcccgg cggggaggtg cccgggactc tgtcttcgtc cggcatccgc
     2101 ggatcatgga actgcgccat ccttgacctt ggcgccgaag cggcttcggc ccgcccgtga
     2161 cgttccctgt ctgtcgaggt gcaccctcat gaagtcccga tcgacgcttg tgacctggct
     2221 gagcgaactc gacggttccc gcctggcacg cgtactcgcc aatcggaagg acgcagcctc
     2281 ctctccggaa ccacgctcgg tgggggaact ggcggaccgt ctccaacgtc cggggtccgt
     2341 ggcactcgtc ctgccccaac tcacgctgcc gtgcttgcag gccactgagg cgctggcagt
     2401 cctgggagca cgagcgaccc gggacagcct cgcggagttg ctcggctcaa gatcccctac
     2461 ggcggtacac gcgctggacg cgaccctgga ggcgctgtcg gatcgggcgc tcgtgtggca
     2521 ggacggaaac gaggcactgc gcatgcccac gcccttgcgg caggcgtgga gcacacccct
     2581 gggacttgac gccccgctgg gcgagctgct ggccggcacc acctcggagg aactgcgcgg
     2641 catgctggcg gtcctgggta tcaagccacc cggcaccaag cagcagcgac tctcggctct
     2701 ggtggagcat cacagtgacg cggaacgggt cgccgcgttg gtggcggggg caccggccgc
     2761 cacacggaag ttgcttgagc ggagcgccag atccacgccg cgtcagtcac tgttcgtcgt
     2821 gttcgggact cctggccgcg acctccaacc aggcgcccga tgggcactcg accgcgggct
     2881 tctgctccag gaccgtcacc ggtacgggcc cgcccggatg ccggtcgagg tggccttggc
     2941 tctgcggggc cccgattggc acgctccgtt cgaacctctg ccgcctgtca cacagttggt
     3001 gcccatcacc tcctcggagg tggagcggga ggccgcggtg gccgccaccg cgttcgcggc
     3061 ccatgccgcc tccgtccttt cggcgtgcgc gaccgctcca ccgacccggc tgaagtcggg
     3121 cgggatcggc gcgcgtgaac tggcccggct cggcaaggcc gcccaagcgg acgacgccgt
     3181 cgtacgcatc gccctggaga ccgcgtacgc cgccggactg ctggcccgcg acggcgatcg
     3241 cgtacctccc accgaggcgt acgacgtctg ggccgagcag gagcccgcag aacaactcgc
     3301 cgtactgctc cgggcatggc gggacctgcc gctcaccccc acccgggcac gcgacgaaga
     3361 caacaaggcg cttcccgcgc tcgccggtgc gcctgactgc ggcggctgtc tgcaggcccg
     3421 ccacgggctg ctcatcgcgg cggcggggct cccggcagga cagggtgcga aggtcgcttc
     3481 ggagctgggg ccgctcgtgg cctggcaccg tccgctcgcc gacgacgcct cgccccagga
     3541 cacggcaccg ttcagcaccg tgatccgcga aggcgaacta ctgggcgtgc tggcacgggg
     3601 tgcgctgtcc ccgctcggtg cgcacctggc ggcccacacc gacgaagagc tcgacatcac
     3661 ggcccggcgg ctgctgcccc ccgcgaccac gacggcccgg atcggcgccg acctcaccgc
     3721 cgtcgtcacc ggcaccccgt ccgcgcgact cgcggcgctg ctggattcga cggccgaccg
     3781 ggagaccagt ggcacagcgt cggtatggcg cttcagcgcc ggtagtatcc gccgggccct
     3841 ggacgccggc cgcaccccgg acgacatcac ggccgacctg gcagccggct ccgccacggc
     3901 cctgccacag ccgctgacct atctcatcgc cgacaccgca cgaggtcacg gacgggtgcg
     3961 catcgccccc gcggcctgtg tcatccacgg cgacgaaccc gcgctcctgg ccgaactcgc
     4021 cgcccaccgc gcactgtcca agctcgccct gcggcggctc gccccgacgg tcctggtcag
     4081 cggcagccca cccgtgacga ctctcgccgc gctccgtgcc gcgggctacg ccccggtcgc
     4141 cgagaccgcc gggggaacgg tacgcatcga aaagcgcctg ccgcagaggg ccgccgctgc
     4201 cgtcccaccc ccgcgaggga acgtcgggcg gcgcggcccc aggaccaccg cgacccacgc
     4261 ctcggagatg ctcatcgacg ccgggacgga cgtggacgtc ctggccgacc ggctgctcaa
     4321 ggccccaccg aacgccccgg aacccgaccc gttcggcagc ggggtgcctt tcgcgacgga
     4381 caccgaggag atcgtcgccg gatacgcgaa gcacctgtcg tacagcgacg tccgccaggt
     4441 cgcccatgcc atcgacgccg gtgcggccat cacggtcgag tacatcgcca cctcgggcag
     4501 ccggaccgta cgcaccctca gcgacctcga actcgacccg ccctacctca acgcctggtg
     4561 ccacctgcgc gaagcggaac gcgtcttcac cctctcccgc atccatggcg tgatgcccgc
     4621 ctaggactcg gcggccaagg ccgggtgccc cggcgagcca cccccgcggg cacctcacga
     4681 gatatacttg actccacatt tgatatcagg aggcgtagat gagtcggacg gttatcgacc
     4741 tggacgacga cctggtcgcg gacgtggcga aagccctcgg gacgaacacc aagaaggaga
     4801 ccgtcaacac cgctcttcgc gaggtgctgg acagccggcg tcgtgccctg gctctcgccc
     4861 ggctgcgggc cgcggcgggc gacggcgcat tcgatctgga actgttcgag aacaaggaga
     4921 tctaccgccg gtgaacgcgg cccagttcct gatcgacacc agcgcgttcg cacggttcat
     4981 gcgcggggaa gcagaacagt acggctggga ccaggccgcc gcggccggac tcatcgcgac
     5041 ctgccccatc accgagctcg agttcttcta cagcgcacgg tcagccgccg accgggcgcg
     5101 cggcatcgag gacatgcggc tgatcttcgg ctgggttccc gtcgacgacc gcgcctacga
     5161 ccgcgcctgg caggtccagg aagccctcac caagcagggg aaacaccgaa gtgccggacc
     5221 tgtcgacctg gtcgtcgccg cgaccgccga gctgcagggg ctcaccctgc tccatcgcga
     5281 tcacgacttc gagtgcatcg ccgcggtgac cggacaagcc ctccagtggt acggcccgga
     5341 acacggcaag taggtcagcg gtggttgcag ttctggttgc gttcaccgcc gtacgacatc
     5401 gttcagaagc cccacccgag ttggctgcac cgcaggtcag aacgctcccg cacatccccg
     5461 tacccccgga cgaacatgtg gaaagcgtgt tgggttcaca ccctcacgag ttcgaatctc
     5521 gtatcctccg ccagtgcctc accgggcacg atgtcgaagg gccccaccgt tcgcggtggg
     5581 gcccttcgtc gtggttctca gccctcgttg tcctggtttt tgtccacagg gggttttggg
     5641 gtcccatacg gcttcggtga tcttccggcc gacgtctttg agtatgacgt cctgctacgt
     5701 ggaggcatct cgcccgcgga tggtgtcgtc gcggacgcgg cgtcggacct gcccgccgag
     5761 acgcactccc acggaatcac gaaaccgacc acgatcgagg cagcccgcgg ctcgttcgcc
     5821 caggccaccg gccgcgcacg acctgaccgg tgccaacgtc ggccaccggc aggtcgtcga
     5881 tgtcggcgat cggcgccgcc gacatcgacc gcggcaaggc cgcctcgatc cgcggccgcc
     5941 gaacaggctg ggatcgccgt cggccaccgc caaaggaatc gacgacaccg tggcctacct
     6001 caccgacaag gccgtctacc tccgctacga cactgcgtcg gccgtcggtc ggccgaccgc
     6061 gacgcatcac cgggggagcg tgcgccaccg gggcctggcc ggagccgggg ccctgctggg
     6121 gctccctgtc ctgcatgccg ccaaccacca ggcccgatac cgcaacaccc tcatcgcata
     6181 cgcaccctca cgtgtggtgc gtgatgtcgg tccagcgcca ggcgcgcagg gacgagtcgg
     6241 tgaagatgcg gtccagcgcc ctgcccagat ccgggtccgt ctccgtctcc gggtccgggt
     6301 ccgtgggcca ccgaaggcga acggtgaagc gttcgcccgc gaactccggt tcgtagtccc
     6361 agccttcggg cagcagggcg atgaaccgta cggctgccag ttccggggcg ccggccgcct
     6421 cggtggagcg gggttcgatc aggacgacgc ggcggcctgt catgagggac ggcggcgtga
     6481 ggacgggaag aacggcaggc ttccgcccga gccgagtgcc tcgtcaaggg ctagcaggac
     6541 ccccgccgtg ccggtggcga ggtcggtcga caggcgcagg gtctggtcgc cgaggaaggc
     6601 ggggtggccc gcgtacggga tggcgtgcca gccgaaggcc accaggtggc ggcgtactgc
     6661 ggcctcggtc tccgacttcg gctccaacac cgacttcggc tccgaccccg gctccggctc
     6721 cggcgttctg tcgcgcaggt gacgcagggc gagcgtcgcc ccggcgcggc cctggaacag
     6781 gcccgcctgg gcttggtaga gggccgccac cgatgactgg aggaggggga aggagtcgtt
     6841 cagctccggc tcggggaagg ggagatgagg gagtacgtcg ctcacgacca tcgccactcc
     6901 cgccccgccc accgccaggt acggcatccg gctgatgccc ggcccggccg acaactcggc
     6961 gaggtcgtga cgcagcgcct ccaccgcccc gtgcagcagc ttccggtcac ccgtcttctc
     7021 gtacagccgc agcaggaaca gtgccgcgcc cgtcgccccg tacagcaggc ccggtcgtgg
     7081 gcgggccgcg tagccgcccg gggtacggtc cgcgaccagc tccgcgaggc gttcggccgc
     7141 gtcgaggtgg ccgaagtgga gcagggagag gccgattccg gggaggccgg cgaagaggga
     7201 gccgtccagg tcgtccagcg gcagggcgag ggcacggtcc aggacttcac gggcctcgac
     7261 cgtacggccc agggcgtcga gggcgtacgc gatgccgtgc aggccgtcgt agaagccggg
     7321 gcgggggtcg gcccagcggc gtacgcgctc ggtcagccag tccacgtgtg cggccgggat
     7381 ctccgtaccc gcgccgccca gcgcccacag gactccggcg gcgccgtggg cgaggtcgag
     7441 gccgccgccc gggtcggtga actgggcgat gtcgccgggg aagaggcggt cctcgcggtc
     7501 cggggtcgcg gtggccagga ttccggccgc gagtgacgcg cgcagggacg gccagtcggc
     7561 gggggtgagg gtctcgggcc agaccggggc agcggcgcgc tcggcgctca ctgcggcctc
     7621 ggtgtccgcc tcggtgtccg cgtcggtgtc cgcctcggtg tccgcgtcgg tctcagcgtg
     7681 cgcgtcggcc gcgtcggcct tggcggcctc ggtcgcctcg ccgccctccg ggcccgccag
     7741 atccgccgcc acccgctccg cgaagtccgc cggtaccggg aagttctccg tcaccagcgc
     7801 gatcagctgc tgtgtcttct cccggcccca gcccaccacc accgtcagcg gcaggaacac
     7861 cgcgagccgc aggcagccga gcgcgtaccg gtcgaccgcc gcgcccacgt aaccggccgg
     7921 ggcgcggaag ccgggcgcgc cgatcgcctg aggtgcctcg tcgtctaccg gggtcgccgt
     7981 ctccaggtcg atgaaggcga tcgtgccgtc cggccggacc aggacgttgt tggggtgcag
     8041 atcaccgaag accacacccc gggcgtgcat ggcccgcacg cccgcgtcga tctggtcgat
     8101 gacggacaac gcccacgagg tgtacgccgc gaacgacccg ggggaggcgt cggcatccgg
     8161 gttcagcagt gggttggact cgtggatgcg ggtatggagc gatgcaccgg gcacgaactc
     8221 ccgtgccagg aagtagtgtt cgcggccttt tcggtagtcg atcagcggcg gtacgcagtc
     8281 cagtcccgcc agccgctcca gcgcccagcg ctcccgctcc agccgggcca ccgcgtccgc
     8341 gccctcctcg tcgaggccgg ccagcgggcg ggcctccttg aggagcacgg aggcggaggc
     8401 cccggtaccg gggccctggc gcaggtccgc ggcctcgtac acgccgcccc cgttggagaa
     8461 gtgcagcgcc ctgaccgcgc ggaacgggaa gtcgcccatc gtgctcgcgt tacgggccgc
     8521 cagcgactcg gcgaggcagt ccggcagcgt cacccacgcg ggcggccgga acccggggcc
     8581 gcgcacatcg gggacgaggc ggccgtccgg gtcctcgatg cagtgcaccg ggtcgccctt
     8641 cgcgtcccgg ccgaggcggg cgacgaagcc gccgtagcgg acgtagagcg ggccggagcg
     8701 ccagcgcagg tcgctgagga tgtacgggcc gggctcgccg cctatctcgg cgtccagctc
     8761 gacgagcacc cgctccagct ggggctcgtc cagcggatag acggtgatga acttgccgct
     8821 cgcgccgcgg tcgccgtact tgctgttgcg ccggctcagg accttggcgc tgcggatgta
     8881 cttgaaggtg agccgctcgc gtacgcagta ggcgcgtacg acgtcgagga tgtggtcggc
     8941 gttgtcccgg gtcgccgaga catggatctt ccagccctgg ccggggagtt cggtgtgcgg
     9001 cggggtcagc accacccagt cgctgttgac ggtccgggtc cagcccgcgg ggggttccgc
     9061 cacgacgtcg gcgggctcgg tggtggcagc ggcggtcgcc gggtcctcgt agaacgcgtt
     9121 gcccgcctgg cagtaagtca cataccggag atccatgatc gttcttcctg tccctctccg
     9181 tctcggcttc tcggcttctc ggcttctcgg cttctcggct accagcgcca ggccggcgcg
     9241 acgtacttgg tgtagagcca ctcccagccc ggccggctgc ccgcgtccag ctgggccgcg
     9301 cccgagacgt cggcgggagt tcggccctgc ccatcacgtg tctccagcgg aaggccgagc
     9361 gccggggtcg gcagggcctc gctgcggacc gggatcaggg ccgacagcgg ggccatggcg
     9421 tccgtgccgt ccgccccgtc gacggcgacc gtcgcggcgc cggtctgctc gcgggtcgcg
     9481 atgcccgcgc ggtagaggcg taccggggca ccggcctcga tcagcgaacg gtcggtggaa
     9541 gggggcagga gcagcgtgat ccggccgtcc ttggccgtcg tatagccgcc gttgacggtg
     9601 tacgggacct ggaccagctg cccgagtacc gcgatggcgg cagcggcgag ggctagcacc
     9661 gcgccgaggc gccaggggag cccgcccgcc gtacgggcct cgcgagcgaa gcggcgtacg
     9721 ccacgcgcca ggtggtggag gaagtagccg atgccgcaca gcacgaggag cgcgcccagg
     9781 gcgccgaggc gctggaggct gtccgaccac agggtgatcg cgcccgccac gatgtagagc
     9841 gggaaggtca tgcagagcag gccgaagggg accgcccagc gcacgccggg cagttcgcgg
     9901 cggtagccgg tgccgccggc cagcaggcgg gccagccatc tgcgggcgtc ggtcatcgcc
     9961 cggtcgcgca gatgcgggat gtcgaggtga ctcatcagcg cgatgtagcc gtccagcttc
    10021 acgaacggca ggaggttgag aacgccggag agataggtga cgacggcgta cacgaggacc
    10081 ccgtcgcgcg ccgccgagtc gcccatgaag agggtggcga gggcggcgcc cccggcgatg
    10141 acggtctgtg tggcgattcc ggcgagtgcg acccgtaccc gctgttcctt gcgcggcagc
    10201 cgccacccgt cggacacgtc gcagaagaag gccggcgaca tgtagaagag catcatgccc
    10261 atccgggtcg gccgtccgcc gtagtacgtg aggaccgcgc cgtggccgat ctcgtggacg
    10321 gcggtggtgg cgagcaccgc gccgatcacg cagaggtaga gcaggggcgc gaaggggcgc
    10381 cccaacgcgc cctggagatc ggccgtctgg agggccaggg cgagcagtcc gccgatcgtg
    10441 acggccgagg cgaccagggc ggccttacgg ttcgcggcgg cctcgaccag cggggcgagc
    10501 cgggccagca gccggtccgg cttgaggagg gtgaactgga gggtgagcgg cgggacgaac
    10561 cggaaccagg aactccggtc cttcttcggc accccgtcgt ccagcacctt cgccccggcg
    10621 agcgtccgca ccgccgagcc gacatcggcc tgggtccagg gcgcgccgag ggcgtcggcc
    10681 aggtcgtcgt ggtcgcgtac gccgtcgacg gcccggacga ggcgggccag gtcctcctgg
    10741 aggcggaagt actggtggct gccgcgctgc accacccagg gcgcacccgg ctcggccggc
    10801 tcgtggacca ccacgtcggg ggcgaggcgg ggacgggcca gccgctcggg ggccagtagt
    10861 acggcaccgg cgggtgtgct ggacatgcct ggttctctcc tcaggacggc gggacgtggc
    10921 gggtttcagc ggactcggac gacgcgggat gtcgtcgggc ggcatcgggc gacgtcagtg
    10981 gccgccaggc ggactcagac agcaacagat gccgtcgggc agctcggacg aacgttggac
    11041 gagggcaggc ggcatcggac gacatcagat gtcgtcaggc agcatcggac aacaacagat
    11101 gtcgtcaggc agcatcggac aacaacagat gtcgccaggc agcttcgaac aaggtcagac
    11161 gacgtcaagc ggctgcgaac gacgttcaga cgacgtcgcg ggcggtgaac agcttccggg
    11221 cgagcagccc tgcggccgcg agccagcccg cgatcaccag cagcgcgagc ggcgtggaca
    11281 gcagctcggg cttcatgtcc cggtagacgg agctctgggc gatcgtcatc aggtatttgc
    11341 cggcgtccgg caccaggacc tgcaccgccg gatcgacgac cagggtcagc gcgacgacgg
    11401 tcacgacggc cccgacctgg tgccggacga tccagccgat cagcgcgccc cagggagcgg
    11461 cgagcgtgtt gacggcgaag acgcccagca ggatcagcca ggtctcgccg tgccacgcgg
    11521 gctcggtccc gttggccgcg agtgcccccc aggcggaggc gagggacagc gcggcggtga
    11581 acagcgcggc gagggcgccc acggcggtgg cgatcagcac cttggcggcg agcaggcggg
    11641 tacggccgcc gctcatcagc acggagcggc cgatggcgcc cgaggtgtac tcgcgggaca
    11701 cgaagaccgc gccgaagagg gaggtgaaca gcgacatcat gaaccaggag cggacgatgt
    11761 catcggtgac ggctgcccgg cccatggtgc cctcgtcgat ggccgtggcg ccctgggagg
    11821 cgtagccgag ggcaccgagc agggacatca ggacgccgca cccggccagg atcagccagc
    11881 cgcggccggt ccaggccttg gcccattcgc cggcgagcag gttacgcatg gttctgtcct
    11941 ccgacagcgg atgatgcggt cgtcgccgtg ccgaccaggg agaagaaccg gtcttcgagg
    12001 cgttcccctt cgcccgcgcc gacgagtccg tcgagcggac cggcgtaccg cagcgagctc
    12061 tggatgatca cgacgtcgtc cacggtctgc tccacctcgg agagcagatg gctggagacg
    12121 aggacggtcc ggccctcgtc ggccaggccg cgcagcaggc cgcgcagcca gcggatgccg
    12181 tccgggtcga ggccgttggc gggctcgtcc aggacgagga gttcggggtc ggggagcagg
    12241 gcggtggcga gcgcgaggcg ctgcttcatg ccggtcgagt agcccttgac ggggcgggag
    12301 gccgcgccgt cggccaggcc gaccagttcg aggacctcct cgacgcgctg cttgggcagg
    12361 cccagggtcc gggcccagat ggtgagttcg cgtcgggcac tggctcccgg cagcggtcct
    12421 acggcgtcca tgctgacgcc cacccggcga gcggcgtggg gcagttcggc gtacgggcgg
    12481 ccgaagacgg ccgcctcgcc ggaggtcggc cggcacaggc cgaggagcat ccgcagcgag
    12541 gtggtcttac ctgctccgtt gcggcctagg aggccgacga tccggccggg ctgcacctcg
    12601 tacgtcaggt cgtcgaccgc cgtgacctcg ccgaagcgct tggtcaggcc gcgcagggcg
    12661 acgacggggg cggcaccggt gcttgaggcg ttcgcggtac tcaacggcgc gccttacgga
    12721 ggttggcacc gatccggacc aggcagctca gcatgacgac accgaggccg gccatgacga
    12781 agatctcgag gccgcccgtc agctgcgtgg tcgcgaccgc catgccgagc gggatgagag
    12841 cgcaggcgaa ggcgaggttc ttgttctcgg ccgctgcctt gtctcggctg ttggccatgc
    12901 tggactcctt ggtggggcga ggtggtggaa aacgaagcgc ggattccgcg gtggcggccc
    12961 agggtcctgt gaggtcccag ggacgccgcc gcggaaatcc gtatgcggtt cagtcgccgc
    13021 tgatcaactg gatccggtgg atccggtgga tccggtggat ccggtggatc cggtggatcc
    13081 ggtggatccg gtggatccgg tggatccggt ggatccggtg gatcaggtgg atcaggtgga
    13141 tcaggtggcg atgaccgcgc tggcgacggt gctgatcacg acgccggtct tgaagccgct
    13201 ccagaagccc ggggcctcca tggcctccag ctcctgcatg cccagctcca gcgatgcgtc
    13261 gaagccgttc ggctcctgcg tgacggtgtc cttcatatcc gttcccctcc cgttgagttg
    13321 agactgaatc gagtcgagtg aatcaggtcc accagccggg ccttcttggc ctcctgctgc
    13381 acgaccacgg gccgatcagg tgatgatcga gacggcgacg cccgtcgaga caccgacggc
    13441 cgacacgacg gtcgcaccca cgacgacgcc accggcggtc caccagcccg gggcctccat
    13501 cgcctcgagc tcctgcatac ccagctccag gtcggagctg aagttgttgt tgtcgaagtt
    13561 ctcctgcatg ggaactcccc cttttctcat gagtgtcgag agccgttgct ctcttttccg
    13621 cccgctcccg ggatcgggag cggaagtctc aggtgtgcgc gggatgcgca gtgcgggcgg
    13681 tgtgcgcggt gcgggcggtg tgcttggtgc tcgtggggtg cacggtgctc gttttggtcg
    13741 cgcccagtgc cgcgtccagc aggcggcgca cgtcctccgc ccggagcccg ccgagcatcg
    13801 gcagcccggc gccccaggcc cgtacggtcc gctcggccag ggcctcgatc tgccccgggc
    13861 cgccggcggt gagccgccgg cccacccgcc agtcgtccat cagggcctcg atcccgtcgg
    13921 ccgggtccgc gggcagggcc tgcgcccggt cccgcggtgc ggcgtcgcgc agccccgccc
    13981 acatccggtg cagccgcggc gcggagccca gtcgtggctc cccgtcgagc acggcccgcc
    14041 acaggtgcgg cagcagcgcg gcgacggcgg tcatcttccg tacgcccagg gccgacgaca
    14101 tctcgttggc gatgagccag cccttgaccg cgtacgggtc gcggccctgg tgcagccatt
    14161 caccgtgcgt gagcccgctg agcttcgcga tgtcgaggcg gagcgcgtcg cccggctttt
    14221 cctcccgtac cgcctcgtag ccgagttgga cgagccgccg ggcgaccgtc tccgtcagac
    14281 ggtcctcggt gcggcggtcg tcccggtggt caccggcgta cggactgacc gcccggaaca
    14341 gcgcctccag gacgccctcc acgaccagtt cgcggggcag tgtggcggtg gccgacggat
    14401 cgagcagtgc cgcctccggc cgcagtacgc cgccgaggat cagccgcttg ccctgcgggt
    14461 acgccaggca ggcgaccgcg ctcagctcgc tgccggtgcc gagggtggtc ggtacggcga
    14521 gcagcgggac ggtacgggtg acctcgcccg gcaggcccat cagaccgccg cgctggggca
    14581 cggtgaggcg ggtgtacgcg accgggttgg cccgcagcag agccgcgatc ttcgcctggt
    14641 cgagcaccga tccgccgccg atggcgacca ccaggccgat gccggcgagc ttgtcggcga
    14701 ggccttcggc gatcgcggca gccgtgccga ggtcaccggg gccggtggtc agtggtgtct
    14761 gggtcgtccg ccagtgggcc cggccgaggc ggtcccgtac cagggccgtg atccccgccg
    14821 tcgcgacagc gctgtccacg aggagggcgg ccgtgcggcc cgccccgtcg gggagccatg
    14881 ccgtgagggc gtcgggaccg atcagcgccc gggtcggtcc gccccggccg tagctcatgc
    14941 cggtacctcc gcgtgcgctt ccgccggcac cgactggccg gtgaacaggg ccagtccggc
    15001 gcggatgcgg tccatcagct cggtcagttc cgcgtcggtg taggtcagcg cggggaagag
    15061 ctggatgccg tggacgccgg ggtgcacgat ggcgcccgcc gtacggatcg cggcgaccag
    15121 ttccgggacg cgtgcctgtg gcagcggttc cccgtccggg gtggtcagtc gcagcgaccg
    15181 gaaacagccc agaccggtgg tgcccgtcac ccaggggtgc tcgtcgacca gcccggacag
    15241 ctccgcgtcc agccgttcgc ccagggcccg gccgagggcg accgcgtcca ggcggcgcat
    15301 ctcggcgatg gtggccagga tggcggcgca ggtggcgggg gtgccggcct gggtctcgcc
    15361 gtgggtcagc atggcgcccg ccgtgtcgaa ggcgtccgcg accgtgtgcg aggcgatgac
    15421 ggctgcggcg gcgctcgtac cgttggtgag ccccttggag gtcaccagga ggtcgggccg
    15481 ggcggaccag cgctgggagg cgaagaagtc gccggtacgg ccgaagccgg tggccacttc
    15541 gtcggcgacc agcaggaagc cgtactcctc gcgcagccgc agcagttctt cgacgtactc
    15601 ctcggtgagc ggcaccgccc ccgagccgag caccggctcg acgacgacgg ccgcgaccat
    15661 agctccctga cgttccatca aggtacggat accgagcggg tcgttggggt cgacgtggcg
    15721 gatgaggcgc tggtcgacgc cgtacacctg ttgtccgagg tcctcaccgg tcagcgcgaa
    15781 gctgccgtac gtcagaccgt ggtagctgcc gcgcagcccg accacgagtt tgcggcgatc
    15841 ctcgccgcgc agtgcgtggt agtggcgggc gagcttcatg accaggtcgt tggcggcgcc
    15901 gccggaggtc gagaagagga cccggccgta ggtgtcggcg ccgcacagct cgacgagggc
    15961 ggcggccgcg gcacgggcgt agctgttctc gtagcggaag acgctcaggt acgaggcttc
    16021 gcggagcgct tccgcggcgg cctgggcgat ggcttcgttg ccgtagccga tgttggtgtt
    16081 ccacaacccg ctggaggcgt cgaggagttc actgccgtcg gcgtaccgga cccgtacccc
    16141 gtgcgcggag accgcgcaga gcgcgtccga gccgtgcagg gcgggggcca ggagggacgg
    16201 ccacagcgcg tgcttcgtgc tcttcgtgct cttcgtgctc ttcgtgtgta cgggactcat
    16261 ggcgtgacct ccgtttcgag cagtacttcg agcagtacgt cgtggtggcg ggagccgacg
    16321 gccggcagcg ggtgccgggc
//
