LOCUS       reptomyces_RBGC_491315 16460 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_491315
VERSION     Streptomyces_RBGC_491315
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_003977875.1
  ORGANISM  GCF_003977875.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1257
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91634"
                     /pseudo=False
                     /translation="MRTLWRQTRSFPPAVRLLMANQFAINLAFYMLMPYLAAHLSDGVG
                     LAAWAVGLVLGVRNFSQQGMFLIGGTLADRLGHKIPIMAGCLLRTVGFALLGWVDDLAT
                     LIVASAATGFAGALFNPAVRAYLAAEAGERRVDAFAVFNVHYQAGMLLGPLLGLALLAA
                     DFRLVCTTAAAVFAALTVLQWRRLPAPPGRTPGAARREGVLSQWRTVAANRPFLLFAAA
                     MIGSYVLTFQVYLALPLAAADALGANATAVTSGLFVVSAAVAVVGQLRLTGWAGQRWRS
                     DQALTRGLAAMGLAFLPLAVVPRGSSAATLAALVVAVVLLAVGSAVVYPFEMDTIVALS
                     GNRLVATHYGLYNTISGLGITLGNLVTGAMWDFAQRHHALWLTWTALTAIGLACAAAVT
                     ALAHTGRLTAGHRPEPAPA*"
     CDS             complement(1283..1983)
                     /protein_domains="PF00072"
                     /protein_domains="PF00196"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91635"
                     /pseudo=False
                     /translation="MTGPGTFSEQNPIRVFLLDDHEVVRRGLTDLLDAEPDISVVGDAD
                     TVGHALVRGPALRPHVAVLDVRLPDGDGITVCRELRSQMPELACLMLTSFDDEDALLDA
                     IMAGASGYVLKQIRGSDLVSAVRTVASGQSMLDPATTARLMRSLRADPAETPSVPPELA
                     SLSPRERDILALIGDGLTNREIGKKLYLSEKTVKNHISRLLAKLGVQRRVQAAVLASHL
                     EQPETGDRPTR*"
     CDS             complement(2117..2793)
                     /protein_domains="PF00571"
                     /protein_domains="PF04972"
                     /protein_domains="PF00571"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91636"
                     /pseudo=False
                     /translation="MLGNPHIVSDVMTHTVAAVGRRATFVEIVRLMQDWKVSALPVLEG
                     EGRVVGVVSEADLLPKEEFRDSDPDRYTQLRRLSDLAKAGAVTAEELMTSPALTTHPDA
                     TLAQAARTMARAKVKRLPVVNELGMLEGIVSRADLLKVFLREDDEIAEEVRREVVAHLF
                     PMSSAAIRVEVHDGVVNLAGRVRDTSLIPVAARLIRAVEGVVDVDFALESPIAAGESTA
                     WGR*"
     CDS             complement(2827..3290)
                     /protein_domains="PF00027"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91637"
                     /pseudo=False
                     /translation="MITTPTPSMLRALPAEHRQRLMQMAREVAFPEGTRLFEEGDRADR
                     FWIIRTGTVELDMRVPGRRPAVIESLRHNELVGWSWLFTPHVWHLGAEATTPVRAYEFD
                     ATTVRTMCREDPALGNAVAQWVGDVLAHRLRSARTRLLDLYAPYGAGSPV*"
     CDS             complement(3413..5133)
                     /protein_domains="PF00916"
                     /protein_domains="PF01740"
                     /protein_domains="TIGR00815"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91638"
                     /pseudo=False
                     /translation="MEQGRSGHVPQWRHLVPGVVALLGYRRSWLRGDVVAGVTVAAYLV
                     PQVMAYAGVAGLPPVAGLWAILPALALYALFGSSRLLSVGPESTTALMTATVVAPLAAG
                     DPDRYATLAVTLAVTVGLLCLVARAVRLGFLADLLSRPVLIGYMAGVALIMMSDQLTKL
                     TGVETTGSKFFPQVWSFAAGVTEAHGATVVLSAAALVLLFLMAKYVRAVPGPLLAVVLG
                     TLAVVLFDLDERYGVKVIGDVPSGLPGLAHPDWAEVPGLVLPALGVLLVGYTDFILTAR
                     AFSGRPDDADDGPELDADQEFLALGAANLGAAALHGFPVSSSASRTALASSSGARSQLY
                     SLIAGFVVLAVLLFLSPLLSRTPSAVLGALVVYAAVRMIDLAGFRRLASFRRRELLLAL
                     GCLAGVLALDILYGVLVAVGLSVAELLTRVARPHDAVLGVVPGIAGMHDVDDYPTARTI
                     PGLLVYRYDSPLFFANAEDFRRRALVAVDEQTASVRWFVLNAEANVEVDITALDALDEL
                     RQELTDRGIVFALARVKQDLREELQAYGLADSVGAERIFPTLPTAVAAYREWSGDR*"
     CDS             5384..6300
                     /protein_domains="PF00582"
                     /protein_domains="PF00582"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91639"
                     /pseudo=False
                     /translation="MTRTVTLSVTAGLDGSRESRAAAEWAAREAQLLGLPLKLIQVWEP
                     VPEPMAQAPLLGVETQQHWSERVPRDAAEGIRARHPGLDVTVEQLSGRPAEVLADEAKD
                     AELLVLGSRGLSGIAGFLVGSVGLAVVAHADRPVVLVRAEEQAADEHESDPVGIPSAAT
                     AFRPVVLGLDIDSPDRELIEFAFAAAARRGTTLRVVHGWNPPPYYAYGLSADLELHASL
                     AQRETTVLTEVMRPWRKKFPEVEVTEESHYGTPGSHLVDASRDASLVVVGRRIRRSSFG
                     AHIGPVTHAVLHHAVAPVAVVPHN*"
     CDS             6325..7190
                     /protein_domains="PF00582"
                     /protein_domains="PF00582"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91640"
                     /pseudo=False
                     /translation="MNAMDLPIVVGVDGSEPSLRAVDWAADEGALRGLPLRLVYASLWE
                     RYEGDALAHDLGKPSEQVRAEDIVTAAARRAHRRRADVKVLTDSLPEEPEYALVRESRN
                     AALLVTGTRGRGGMAEALLGSVSLTVAGHAHCPMVVVRGSQDNAVRPGGRIVVGVGEGA
                     PVRFAFEEARLRGASVEAVRAWRSPARETTDHPLLAGEPARLHEQEAAQALEKALRGMP
                     ADVEVHRRVVEGHARTVLADASRDADLLIVGARRRPRHFGLQLGRVAHGVLHHSVCPVA
                     VVPERDG*"
     CDS             7306..9686
                     /protein_domains="PF09364"
                     /protein_domains="PF09363"
                     /protein_domains="PF03894"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91641"
                     /pseudo=False
                     /translation="MSKAEHQDATELSADELRKLDAHWRAANYLAAGQIYLLSNPLLTE
                     PLKPEHIKPRLLGHWGTSPGLNLVYTHLNRVIGARGLDTLCVWGPGHGGPSVLAGSWLD
                     GSYSEIYPDVPRDGEGMERLFRQFSFPGGVPSHVAPEVPGSIHEGGELGYSLAHAYGAA
                     FDNPDLLVACVIGDGEAETGPLAASWHSNKFLDPVHDGAVLPILHLNGYKIANPTVLSR
                     LPAAELDQLLRGYGHDPLHVSGDDPATVHRALARALDEALDRIALMQRSARDGGVAERV
                     RWPMIVLRTPKGWTGPAEVDGLPVEGTWRAHQVPLAGVRENPEHLRQLEAWLRSYRPQE
                     LFGPDGRPVADVLACVPDGSRRLGATAHANGGLLVRDLPIGPLDSFAVPVDKPGTTMHE
                     PTRVLGDLLRQVMQDTRRRRDFRVVGPDETASNRLQALYDASGKAWQAQTLPVDEHLDR
                     HGRVLEILSEHTCQGWLEGYLLTGRHGLFSCYEAFVHIVDSMVNQHIKWLRTARQLPWR
                     APIASLNYLLTSHVWRQDHNGFSHQDPGFVDHVLNKSPEVVRVYLPPDANTLLSVADHA
                     LRSRDYVNVIVAGKQPCFDWLSMDAARAHCARGAGIWDWAGTENGGEPDVVLACAGDVP
                     TQEVLAAAQLLRRHLPQLAVRVVNVVDMTRLLPREEHPHGMTDFEYDGLFTADKPVIFA
                     YHGYPWLIHRLAYRRTGHKNLHVRGYKESGTTTTPFDMVVRNDLDRFRLVMDVIDRVPG
                     LAVRAAAVRQEMADARTRHHDWIREHGTDLPEIADWTWST*"
     CDS             9847..10031
                     /protein_domains="PF12724"
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_91642"
                     /pseudo=False
                     /translation="MTDKVLVAYGTTNGSTARIAEAVADVLRKDGLAVDTLPARSVPSV
                     APYDAVVIGGGLYAGR*"
     CDS             10054..10346
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91643"
                     /pseudo=False
                     /translation="VRRHGRALTERPLWLFSSGPLDATASERDIPPVPGVKKAMARLDA
                     RDHVTFGGCLEEGAKGWVAGMILRSGKGGDFRDFTAIEAWAERVAAELRNEA*"
     CDS             12019..13778
                     /protein_domains="PF13185"
                     /protein_domains="PF07730"
                     /protein_domains="PF13185"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91645"
                     /pseudo=False
                     /translation="VGSPEEAREARIRLPQLRLDELLEELQARLDAARGTRDRVHSLLE
                     AVLSVGRELDLEQALHSIVEAAAVLVDAEYGALGVIGPDGKRLSAFHTVGIAEEQIARI
                     GHYPEGHGILGELIRHPEPLRLAKLSEHSASYGFPPNHPPMNTFLGVPIRVRDQIFGNL
                     YLTEKRGGAQFDEDDVAVTSTLAVAAGVAIDNARLYEESRLRERWLRATAEITHTLMSG
                     AERGEVLGLIADRAREITGAALAMVAMPMEDTDSLSVELAIGPEAQSLRGLVLPGDSGL
                     LGEAFATAAPVTSPDIAHDELSEMGVPPAEGRGRISAGPPSLTGPAVAVPVGTGEGGVR
                     GVVLLVRAAGQTVFAGKEIEPLQGFAAQAAVAMELAERRQDAAEVAVLKDRDRIARDLH
                     DLAIQRLFATGMTLQSAGRFIEHPEASERVVRAVDDLDETIKIIRSTIFGLRAREGVAG
                     AGLRARVVRVAGEAAPVLGFAPSVRMEGLVDTEVPREIADHVVAVLSEALTNIARHARA
                     DRADVALTADSRQVRLTVGDNGVGVPEGGRRSGLRNMAERARHLGGDLELSSPEGGGTT
                     LAWCVPLPAE*"
     CDS             13942..14258
                     /protein_domains="PF00582"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91646"
                     /pseudo=False
                     /translation="MTLPLVVGVDGSDASLLAVDWAVDEAARGDHPLRLVYASLWERYE
                     GAVPSTGGERPSERVLAEHIVASAAERAALRRPDVPVTTGVVPADPVDALCTRATTPSP
                     W*"
     CDS             14256..14809
                     /protein_domains="PF00582"
                     /protein_domains="PF00582"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91647"
                     /pseudo=False
                     /translation="VTGERGRGELKGLLLGSVSLGVAARAHCPVIVVRGDETGLVGLHE
                     QILFGAGDLATGVQAVRFALREAEERGCAVDAVRAWRRPALEGAAVFTEDAAQEPEERA
                     AAQLGELLGEAMAEGPGVLVRRTTVEGPAPRILVDRSADADLVVIGARHRHGHFGLQLG
                     HVGHTLLHHAHCPVAIVPQMT*"
     CDS             15376..16460
                     /protein_domains="PF02771"
                     /protein_domains="PF02770"
                     /protein_domains="PF00441"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_91648"
                     /pseudo=False
                     /translation="MSSLDLLSEDERFVVRTVRDFVDKDVKPVVRELERTDTYPEALIE
                     RMKELGVFGLAVPQEYGGTPVSMPCYVLVTEELARGWMSLAGAMGGHTVVAKLLLHFGT
                     EEQRQRHLPRMATGETRATMALTEPGGGSDLQAMHTVARREGDGYVVNGAKTWITNSRR
                     SQLIALLCKTDPDAEPAHRGMSVLLVGHGPGLTVSRDLPKLGYKGVESCELSFENHRAP
                     ADALLGAVEGHGFAQMMRGLETGRIQVAARALGVGRAALEDALTYAQQRESFGKPIWQH
                     QSIGNHLADMATSLTAARQLTLYAARRAEAGHRVDMGRPAWRSSSPPRRPCRSPSTPSA
                     STAATATRPSSTSSATSGTRP*"
ORIGIN
        1 atgaggacgc tgtggcggca gacccgctcc ttcccgcccg ccgtacggct gttgatggcc
       61 aatcagttcg ccatcaacct cgccttctac atgctgatgc cctacctcgc cgcccatctg
      121 tccgacggag tcggcctggc ggcctgggcc gtgggactcg tgctgggtgt acgcaacttc
      181 tcgcagcagg gcatgttcct catcggcggc accctcgccg accgcctcgg ccacaagatc
      241 ccgatcatgg cgggctgcct gctgcgcacc gtgggcttcg cgctgctcgg ctgggtcgac
      301 gatctcgcca ccctgatcgt ggcctccgcc gccaccggct tcgccggcgc cctgttcaac
      361 ccggcggtcc gcgcctacct cgccgccgaa gcgggcgagc ggcgggtgga cgcgttcgcc
      421 gtgttcaacg tccactacca ggccggcatg ctcctggggc cgctgctcgg actcgcgctg
      481 ctcgccgccg acttccggct cgtgtgcacg accgccgcgg ccgtcttcgc cgcgctgacc
      541 gtgctccagt ggcgccgtct gcccgcccct cccggtcgta ccccgggcgc ggcccgccgg
      601 gagggggtgc tctctcagtg gcggacggtc gccgccaacc ggccgttcct gctcttcgcc
      661 gccgcgatga tcggctcgta cgtgctgacc ttccaggtct acctggcgct cccgctggcg
      721 gccgccgacg ccctcggcgc caacgccacc gcggtcacca gcggactgtt cgtcgtctcg
      781 gccgcggtcg ccgtcgtcgg ccagttgcgc ctgaccggct gggccgggca gcgctggcga
      841 tccgaccagg cgctgacgcg ggggctggcc gcgatggggc tggccttcct gccactcgcg
      901 gtcgtcccgc gcggctcctc ggcggcgacg ctggctgctc tggtcgtcgc ggtggtcctg
      961 ctcgcggtgg gttccgccgt ggtctatccg ttcgagatgg acacgatcgt cgctctgtca
     1021 ggcaaccgcc tggtcgccac ccactacggc ctctacaaca ccatctccgg cctgggcatc
     1081 accttgggca accttgtcac cggagccatg tgggacttcg cacagcggca ccacgccctc
     1141 tggctgacct ggacggccct gaccgccatc ggcctcgcct gcgccgccgc tgtcaccgcc
     1201 ctcgcccaca ccggcaggct caccgccggg caccggcccg agcccgctcc cgcctgatcg
     1261 gcgcgggccc gcgcggagtg ctcaccgcgt ggggcggtcc ccggtctccg gctgttccag
     1321 gtgggaggcc aggaccgcgg cctggacgcg gcgctggacg cccagcttgg ccaacagccg
     1381 cgagatatgg ttcttgacgg tcttctccga aagatagagc ttcttgccga tctcgcggtt
     1441 ggtcagaccg tcgccgatca gggcgagaat gtcccgctcg cgcggcgaca ggctcgccag
     1501 ctccggcggc acggacgggg tctcggcggg gtcggcccgc agcgagcgca tcagccgggc
     1561 cgtcgtcgcg gggtccagca tggactggcc cgaggctacg gtgcgcaccg ccgagaccag
     1621 gtcggagccc ctgatctgct tgagcacgta gcccgatgcg ccggccatga tggcgtcgag
     1681 cagggcgtcc tcgtcgtcga acgaagtcag catcagacag gccagctccg gcatctggct
     1741 gcgcagctca cggcagacgg tgatgccgtc gccgtccggg aggcgtacgt cgagcaccgc
     1801 gacgtgcggg cgcagggccg gaccgcggac cagggcgtgc ccgaccgtgt ccgcgtcgcc
     1861 gaccacggag atgtccggtt cggcgtcgag caggtcggtc aggccccgac gtacgacctc
     1921 gtggtcgtcc agcaggaaca cgcggatcgg gttctgctcc gagaacgtgc ctggccctgt
     1981 catgacgacc ccttgttccc ctgtggctca cggactgctt ctcgtatcga tcatcgctcg
     2041 ccggggccgg tcgcaccagg gccgaccggc cctagtggac cccgagaagc accccgatcg
     2101 gcccgggagg ctccctcacc ggccccaggc ggtgctctca cctgccgcta tgggggactc
     2161 cagggcgaag tccacgtcca ccacgccttc gacggcacgg atcagacggg cggcgaccgg
     2221 gatcagggac gtgtcccgga cgcgaccggc gaggttcacc acgccgtcgt ggacctcgac
     2281 ccggatcgcc gcggacgaca tggggaagag gtgggcgacc acctcgcgcc gcacctcctc
     2341 ggcgatctcg tcgtcctcgc gcaggaacac cttgagcagg tcggcccggc tgacgatgcc
     2401 ctccagcatg cccagttcgt tgacgaccgg cagccgcttg accttggcgc gggccatcgt
     2461 ccgggcggcc tgcgccagcg tcgcgtccgg gtgggtggtg agcgcggggg aggtcatcag
     2521 ttcctccgcg gtgaccgcgc cggccttcgc caggtcggac aggcggcgca gctgggtgta
     2581 ccggtcgggg tcgctgtcgc ggaactcctc cttgggcagc aggtcggcct cggagacgac
     2641 gccgaccacc cggccctcgc cctccagcac gggcagagcg ctgaccttcc agtcctgcat
     2701 cagccgcacg atctccacga atgtggcccg gcggccgacg gcggcgaccg tgtgcgtcat
     2761 gacgtcgctg acgatgtgcg ggttgccgag catgacggct cctcctcact tggctcgcgg
     2821 gcgggtcaga cggggctgcc ggcgccgtac ggggcgtaca gatccagcag ccgggtgcgg
     2881 gccgagcgca gccggtgtgc cagcacgtcg ccgacccact gggcgacggc gttgccgagc
     2941 gccggatcct cccggcacat cgtgcgcacg gtcgtcgcgt cgaactcgta cgccctcacc
     3001 ggggtcgtcg cctcggcgcc cagatgccat acgtgcgggg tgaacagcca ggaccagccg
     3061 acgagttcgt tgtgccgcag gctctcgatg acggccggcc ggcggcccgg cacacgcatg
     3121 tcgagttcga cggtgccggt gcggatgatc cagaaccggt ccgccctgtc gccctcctcg
     3181 aacaggcgcg tcccctccgg gaaggccacc tcgcgtgcca tctgcatgag ccgttgccgg
     3241 tgttcggccg gcagcgcgcg cagcatgctg ggcgtgggtg tggtgatcat ggcgtgcctc
     3301 ccgacgggtg cagggacttc cactgccagc gtccgcccgc cggccacgcc ggaccatggg
     3361 ccacccggcc cctcgcgccg ggccacccgg ctcccgcgac cgaggccccg cctaccggtc
     3421 gcccgaccac tcccggtacg cggcaacggc ggtcggcagg gtcggaaaga tccgctccgc
     3481 ccccacggag tccgcgagac cgtacgcctg gagctcctcg cggaggtcct gcttcacacg
     3541 ggcgagggcg aacacgatgc cgcggtccgt gagctcctgg cgcagctcgt cgagggcgtc
     3601 cagcgcggtg atgtcgacct ccacgttggc ctcggcgttc aggacgaacc agcggacgga
     3661 cgcggtctgc tcgtccacgg cgaccagggc gcggcggcgg aagtcctcgg cgttggcgaa
     3721 gaagagcggg gagtcgtagc ggtagaccag cagcccgggg atcgtgcggg cggtcgggta
     3781 gtcgtcgacg tcgtgcatgc cggcgatgcc gggcaccaca cccaggaccg cgtcgtgcgg
     3841 ccgggcgacc cgggtcagca gctcggccac cgacaggccg accgcgacga ggacgccgta
     3901 caggatgtcc agggcgagta cgccggccag gcagccgagg gcgagcagga gttcgcggcg
     3961 gcggaaggac gccaggcggc ggaagcccgc gaggtcgatc atgcggaccg ccgcgtacac
     4021 gacgagcgcg ccgaggacgg ccgacggcgt ccggctgagc agcgggctga ggaacagcag
     4081 gaccgcgagg accacgaacc cggcgatcag cgagtacagc tggctgcggg cgccggacga
     4141 ggaggcgagc gcggtccggc tcgcgctgct gctgaccggg aagccgtgca gggcggcggc
     4201 accgaggttg gccgcgccca gcgccaggaa ctcctggtcg gcgtcgagct cggggccgtc
     4261 gtccgcgtcg tccgggcggc cggagaacgc ccgcgcggtc aggatgaagt ccgtgtaccc
     4321 gaccaggagt acgccgaggg cgggcagcac cagaccgggc acctcggccc agtccgggtg
     4381 ggcgaggccg ggcaggcccg aggggacgtc gccgatcacc ttgacgccgt accgctcgtc
     4441 gaggtcgaag agcaccacgg cgagcgtgcc gaggaccacg gcgagcagcg gaccgggcac
     4501 ggcacggacg tacttcgcca tcaggaagag cagcacgagg gcggcggccg acagcacgac
     4561 ggtggccccg tgcgcctccg tcacgccggc cgcgaacgac cacacctgcg ggaagaactt
     4621 cgaccccgtc gtctcgaccc cggtcagctt ggtcagctgg tccgacatca tgatcagcgc
     4681 cacgcccgcc atgtagccga tcagcaccgg acgcgagagc agatccgcga ggaagccgag
     4741 ccgcaccgcc cgcgcgacca ggcacagcag gccgacggtg accgcgaggg tgacggccag
     4801 ggtggcgtac cggtcggggt cgccggcggc gagcggggcg accaccgtgg ccgtcatcag
     4861 cgcggtcgtg gactcggggc cgaccgacag caggcgggac gacccgaaca gcgcgtacag
     4921 ggcgagtgcg ggcaggatcg cccacagtcc cgcgaccggc ggcagcccgg ccacacccgc
     4981 gtacgccatc acctggggga cgagatacgc cgccacggtg acgccggcca cgacgtcgcc
     5041 gcgcagccac gaccgtcggt agccgaggag ggcgacgact cccggcacca ggtgccgcca
     5101 ctgcggaacg tgcccgctcc tgccctgctc catcggccac ccttctccgt cgggcctcag
     5161 gatccaccgg cgtgcccgcg gccgcgacag gtgaatcgat tccggccgag catgcacccc
     5221 aacgggcctt tccggcacct ccgttcagcc cacgggttcc cgaagcggcc agggccggtc
     5281 ggccccttgc agggacttgc ggcccctgcc gggctcgcgg tccgtgggcg acgctcgtat
     5341 cgggaccccc gactcgggac ccccgattca ggaggtggaa ccatgacccg caccgtcact
     5401 ctcagcgtga ccgccgggct cgacggctcg cgcgagagcc gcgcggcggc cgagtgggcg
     5461 gctcgcgaag cacagttgct cggtctgccg ctgaagctga tccaggtgtg ggagcccgta
     5521 cccgagccca tggcccaggc gccgctcctc ggcgtcgaga cccagcagca ctggagcgag
     5581 agagttccgc gggacgcggc cgaaggcatc cgggcccggc accccggcct cgacgtgacg
     5641 gtcgagcagc tgtccgggcg gcccgcggag gtgctggccg acgaggcgaa ggacgccgaa
     5701 ctcctcgtcc tcggctcgcg cggactcagc ggcatcgccg gcttcctcgt cggctcggtc
     5761 ggcctcgcgg tcgtggccca cgccgaccgg cccgtcgtcc tggtccgcgc cgaggaacag
     5821 gccgccgacg agcacgagag cgaccccgtc ggcataccgt ccgccgcgac cgcgttccgg
     5881 cccgtcgtcc tcggtctcga catcgacagc cccgaccgtg agctgatcga gttcgcgttc
     5941 gccgccgctg cccgccgggg caccaccctg cgggtcgtac acggctggaa cccgcccccg
     6001 tactacgctt acggcctgtc cgcggacctc gaactccacg cgtccctcgc acagcgcgag
     6061 accacggtcc tcaccgaggt catgcgcccg tggcgcaaga agttcccgga ggtcgaggtc
     6121 accgaggaat cccactacgg cacccccggc agccatctcg tcgacgcctc ccgggacgcg
     6181 tccctggtcg tcgtcggacg ccggatccgc cgcagttcgt tcggcgccca catcggcccc
     6241 gtcacgcacg ccgttctcca tcacgccgtg gcccccgtgg ccgtcgtacc gcacaactga
     6301 cggaaatccg gaggagttga aacatgaacg cgatggacct gccgatcgtc gtcggtgtcg
     6361 acggctccga gcccagcctg cgggccgtcg actgggcggc cgacgagggc gcgctgcgcg
     6421 gcctgccgct tcggctggtg tacgcctcgc tgtgggagcg gtacgagggc gacgccctcg
     6481 cccacgacct gggcaagccg tccgaacagg tgcgggccga ggacatcgtg accgccgcgg
     6541 cccggcgcgc ccatcgccgc cgggccgacg tgaaggtgct gaccgattcc ctgcccgagg
     6601 aacccgagta cgcgctggtg cgggagagcc gcaacgccgc gctgctggtg acgggcaccc
     6661 gtggccgcgg cggcatggcg gaggcgctgc tcggctccgt gtccctgacc gtcgccgggc
     6721 acgcgcactg cccgatggtc gtcgtgcgcg gcagccagga caacgcggtc cggccgggcg
     6781 gccggatcgt cgtgggggtg ggcgaggggg cgcccgtccg gttcgccttc gaggaggcac
     6841 ggctgcgcgg agcgtcggtc gaggccgtac gggcctggcg gtcgccggcg cgtgagacca
     6901 ccgatcaccc gctgctcgcc ggagaacccg cccggctgca cgagcaggag gcggcgcagg
     6961 ccctggagaa ggccctgcgg gggatgcccg ccgatgtgga ggtgcaccgg cgggtcgtgg
     7021 agggccacgc acggaccgtg ctggcggacg cctcccgcga cgccgacctg ctcatagtcg
     7081 gggcccggcg ccgtccgcgg cacttcgggc tccaactggg ccgtgtggcg cacggggtgc
     7141 tgcatcactc cgtctgcccg gtcgcggtcg tgcccgagcg agacggatga cgtgcggcgg
     7201 ggtacccggc cggacggccc cgatgaccga ccggccggcc ccatcgaccg actgaacctg
     7261 aaatcacggc agttcgcagt accgacgact ccggagtcgc cttcatgtcc aaggccgagc
     7321 accaggatgc caccgaactc tccgccgacg agctgcgcaa actcgacgcg cactggcggg
     7381 ccgccaacta tctggccgcg ggccagatct atctgctgtc caaccctctg ctgaccgagc
     7441 cgctgaagcc ggagcacatc aagccgcggc tgctcggcca ttggggcacc tcgccgggcc
     7501 tgaacctcgt gtacacccac ctcaacaggg tgatcggggc acgcgggctc gacacgctgt
     7561 gcgtgtgggg gccggggcac ggcgggccgt ccgtgctcgc cgggtcctgg ctggacggca
     7621 gttacagcga gatctacccg gacgtgccgc gggacggcga ggggatggag cggctgttcc
     7681 ggcagttctc cttcccgggc ggcgtgccga gccatgtcgc ccccgaggtc ccgggatcca
     7741 tccacgaggg cggcgagctc ggatactccc tcgcccacgc ctacggcgcc gccttcgaca
     7801 acccggacct gctggtcgcc tgcgtgatcg gcgacggtga ggccgagacc ggcccactgg
     7861 ccgcctcctg gcactccaac aaattcctcg acccggtgca cgacggcgcc gtcctgccga
     7921 tcctgcacct caacggctac aagatcgcca acccgaccgt gctgtcccgg ctgcccgcgg
     7981 ccgagctcga ccaactgctg cgcggctacg gccacgaccc gctccacgtc agcggtgacg
     8041 accccgccac cgtccaccgc gcgctggccc gtgctctcga cgaggcgctg gaccggatcg
     8101 ccctgatgca gcggtcggcc cgcgacggcg gcgtcgccga gcgcgtgcgc tggccgatga
     8161 tcgtgctgcg cacaccgaag ggctggaccg gccccgccga ggtcgacggc ctgcccgtgg
     8221 agggcacctg gcgcgcccat caggtcccgc tcgccggcgt gcgcgagaac ccggagcacc
     8281 tgcggcagct ggaggcgtgg ctgcgctcgt atcggccgca ggagctcttc ggtccggacg
     8341 gccggcccgt cgccgacgtc ctcgcctgcg tccccgacgg ctcccgccgc ctgggcgcca
     8401 ccgcgcacgc caacggcggg ctcctcgtcc gcgacctgcc catcggaccc ctggactcct
     8461 tcgccgtacc ggtcgacaag cccggcacga ccatgcacga accgaccagg gtcctcggag
     8521 atctgctgcg acaggtcatg caggacaccc gcaggcgccg ggacttccgg gtcgtgggcc
     8581 ccgacgagac cgcgtccaac cggctccagg cgctctacga cgccagcggc aaggcgtggc
     8641 aggctcagac cctgccggtc gacgaacatc tcgaccggca cggccgcgtg ctggagatcc
     8701 tgtccgaaca cacctgccag ggctggctgg agggctacct cctcaccgga cgccacggac
     8761 tcttctcctg ctacgaggca ttcgtccaca tcgtcgactc catggtcaac cagcacatca
     8821 agtggctcag gacggcccgg cagctgccct ggcgcgcgcc catcgcctcc ctcaactacc
     8881 tgctgacctc gcacgtgtgg cggcaggacc acaacgggtt ctcccaccag gaccccggct
     8941 tcgtcgacca cgtcctcaac aagagccccg aggtcgtccg ggtctatctg ccgccggacg
     9001 ccaacaccct gctctccgtc gccgaccacg ccctgcgcag ccgcgactac gtcaatgtga
     9061 tcgtcgccgg caagcagccc tgcttcgact ggctgtccat ggacgccgcc cgcgcccact
     9121 gcgcacgcgg cgccggcatc tgggactggg ccggcacgga gaacggcggc gaaccggacg
     9181 tggtgcttgc ctgcgccggt gacgtgccca cacaggaggt gctggccgcc gcgcagctgc
     9241 tgcgccggca cctgccgcag ctcgcggtcc gcgtggtcaa cgtcgtcgac atgacccggc
     9301 tcctgccgcg cgaggaacac ccgcacggca tgaccgactt cgagtacgac ggcctgttca
     9361 ccgccgacaa gccggtgatc ttcgcctacc acggctaccc gtggctgatc caccgcctcg
     9421 cctaccgccg taccggccac aagaacctgc atgtgcgcgg ctacaaggag tccggcacca
     9481 cgaccacccc cttcgacatg gtcgtccgca acgacctcga ccgtttccgc ctggtcatgg
     9541 acgtcatcga ccgcgtcccc ggcctcgccg tgcgcgccgc cgccgtacgg caggagatgg
     9601 ccgacgcccg cacccgccac cacgactgga tccgcgaaca cggcaccgac ctgccggaga
     9661 tcgccgactg gacctggagc acctgaaccc cggaggggac aggcgccgcc gatcgccggt
     9721 cccctccgcg caaacctgtc gcgtccgcgc cttccggggc cgaacggacc ccgggtcggt
     9781 cccgggcagc ccatgggatc gggcgctcgg gtgtcgcacg gtgggagtgg aggaggcgaa
     9841 ccgtcatgac cgacaaggtg ctggttgcct acggaacgac caatggatcg accgcgcgga
     9901 tcgccgaagc cgtcgccgac gtcctgcgca aggacgggct ggcggtggac acgctgcccg
     9961 cccggtccgt gcccagcgtg gccccgtacg acgccgtcgt gatcggcggc ggactgtacg
    10021 ccggacgctg acacaaggac gcccgccgct tcgtgcggcg gcacggccgg gccctgaccg
    10081 agcgcccgct ctggctcttc agcagcggac ccctcgacgc cacggcctcc gagcgggaca
    10141 tcccgcccgt gcccggcgtg aagaaggcca tggcacggct ggacgccagg gaccacgtca
    10201 cgttcggcgg ctgcctggag gaaggcgcca agggctgggt cgccgggatg atcctgcgct
    10261 ccggcaaggg cggggacttc cgggacttca ccgcgatcga ggcgtgggcg gagcgcgtgg
    10321 ccgccgagct gaggaacgag gcgtagcgag aggcaccgta cgaagggcac cccgtccggc
    10381 cccgcggggg tcccgtccgg cccaagcggg gcccgtgcat ccgcgccaag ctggacgtgc
    10441 ggggcaattc cggcaccggg gtgccgacgg gcgcgaaccg cctgggggac cccaccgccg
    10501 ggcccgtgct ccgcgacacg tcgagtgggg tgaggagcgt catgaaaggc tacgtgttcc
    10561 acggcgccgg agagtccgcc tgggaagagg tcccggaccc ggccatcaag gagcccaccg
    10621 acgcgatcgt gcgcgtcgga gcggtcacca tctgcggcac ggacctgcac atcctcaagg
    10681 gcgacgtgcc cgaggtacag cccggtaccg tcctcggcca tgaggcggtc ggtgagatcg
    10741 tcgaggtcgg cagcgacgtg cgcacggtgc ggccggggga ccgggtcctg gtctcctgca
    10801 tcacctcgtg cgggcgctgc tcctactgcc ggcagggggc ctacggccag tgccgtggcg
    10861 gtggcggctg gatcctcggc catctgatcg acggcacgca ggccgagtac gtccgggtgc
    10921 cgtacgccga cctgtccgtg cacccgctgc cgggcgccat ggacagcaag gacgcggtcc
    10981 tgctggccga catcctgccg acctcctacg aggtgggcgt cctcaacgga aacgtccggc
    11041 ccggcgacac cgtcgtcgtg gtcggcgcgg gccccatcgg actggcggcc gtcgccacgg
    11101 cccggctgtt ctcgcccgag cggatcgtcg ccgtcgacct ggcccccgcc cgtctggagg
    11161 ccgcccggca gctcggcgcc gacgcggtgg ccgacgcccg ggaggcaccg gaacagctgg
    11221 tcaccgacct caccgacggg ctcggcgcgg acgtcgtcat cgaggcggtc ggggtaccgg
    11281 agaccttcga gctgtgcacc aggatggtcc ggcccggtgg gcacgtcgcc aacgtcggcg
    11341 tgcacggcgc ccccgcgacc ctgcacctcg aagacctgtg gatcaagaac atcaccatca
    11401 cgaccggcct ggtcgacacg tactccaccc cgaccctgct gcggatgacg gccgcgggcc
    11461 ggctgcccac ctccgagctg gtcacccaca ccttcccgct ggacctgatg gaggaggcgt
    11521 acgacgtctt cggcggcgcc gccgacaccg gggccctgaa ggtcgtgctg ggggaggagc
    11581 ggcaccagga ggtcgtcccg gtgagcgggg cctgacagcc gggtgcgggt caggacgccg
    11641 ggcgtcgccg gttggggggc aggcggcgcc cgagcggtcc tccgcggtga gcatgacggg
    11701 cttccgtcgg gggtgcgttg cgcatggacg aggccggcga tacgcagtgc ggtgcggtgt
    11761 ggacaggaac ggagcgacac cgcgggggat cggtgccgct ccttcctcca ccatctctcg
    11821 tgtcaccgcc gggtgccagg gccgatgggc cccgatcacg gtccggacgg ccggaactcc
    11881 tcgtcaccgg caccgccccg tgcgccggac cagggccggc ggtccgaatc cgcaccgccg
    11941 cgcaccgcgg gccggtagcg tgaccggtgt ccggagcggc cggtgcccga ccgcccacgg
    12001 gactggagga gacgcaggtg ggaagccccg aggaagcccg ggaggcccgc atccggctgc
    12061 cgcagctgag gctggacgag ctgctggagg agctccaggc ccggctcgac gccgcccgcg
    12121 gcacacgcga ccgggtgcac agcctgctgg aggcggtgct ctccgtcggc cgcgagctgg
    12181 acctggaaca ggccctgcac agcatcgtgg aagccgccgc cgtgttggtc gacgccgagt
    12241 acggcgccct cggggtgatc ggacccgacg gaaagcggct ctccgccttc cacaccgtcg
    12301 ggatcgccga ggagcagatc gccaggatcg gccactaccc ggagggccac ggcatcctcg
    12361 gcgagctcat ccgtcacccc gagccgctgc gcctggccaa actctccgag cattcggcgt
    12421 cgtacggctt cccgccgaac catccgccga tgaacacctt cctcggcgtc cccatccggg
    12481 tgcgcgacca gatcttcggc aacctgtacc tgaccgagaa gcggggcggg gcgcagttcg
    12541 acgaggacga cgtagccgtg acgtcgaccc tcgcggtggc ggccggtgtc gccatcgaca
    12601 acgcccgcct ctacgaggag tcccggctgc gcgagcgctg gctgcgggcg acggcggaga
    12661 tcacccacac tctgatgtcc ggcgccgagc gcggtgaggt gctcggactg atcgccgacc
    12721 gcgcccggga gatcaccggc gccgcgctgg ccatggtcgc gatgccgatg gaggacaccg
    12781 actcgctcag cgtggaactc gccatcggac cggaggcgca gtcgctgcgc ggactggtgc
    12841 tgcccggcga cagcggcctc ctcggcgagg ccttcgccac ggccgctccc gtcaccagcc
    12901 cggacatcgc ccacgacgag ctcagcgaga tgggggtccc cccggccgaa ggccggggga
    12961 ggatctcggc gggacccccg agcctcaccg gccccgccgt cgccgtaccc gtcggaacgg
    13021 gggagggcgg cgtacgaggc gtcgtcctgc tcgtccgcgc ggccgggcag accgtgttcg
    13081 ccggcaagga gatcgaaccg ctccagggct tcgccgcgca ggccgccgtc gccatggaac
    13141 tcgcggagcg ccggcaggac gcggccgagg tcgccgtgct caaggaccgc gaccgcatcg
    13201 cccgcgacct gcacgacctg gcgatccagc ggctgttcgc caccgggatg accctccaga
    13261 gcgcgggccg cttcatcgag cacccggagg cctccgagcg ggtggtgcgt gccgtcgacg
    13321 acctcgacga gaccatcaag atcatcaggt cgacgatctt cggcctgcgc gcacgtgagg
    13381 gcgtcgcggg cgcgggactg cgggcgcgtg tggtgcgggt cgcaggcgag gcggcaccgg
    13441 tgctcggctt cgcgcccagt gtgcggatgg agggtctggt ggacacagag gtgccgcgcg
    13501 agatcgccga ccacgtcgtc gccgtgctct ccgaggccct caccaacatc gcccgccacg
    13561 cccgtgccga ccgcgccgac gtggccctca ccgccgactc ccgccaggtc cgcctcaccg
    13621 tcggcgacaa cggcgtgggc gtcccggaag gcggccgccg cagcgggctg cgcaacatgg
    13681 ccgagcgggc acgccacttg ggcggcgacc tggaactgag cagcccggag ggcggaggca
    13741 ccacgttggc ctggtgcgtg ccgctaccgg cggagtagac ccccgctcgg gggcgccccc
    13801 gccatcggga ccgacgggtt gggccgaagg tccctcccct gtgccccatg cgcctctcgt
    13861 ggcggccccc gccgggtgcg acggtgggat cagtgccccg gttgtccgac agggcggccc
    13921 ggcaagaggt ggtgaggacg atgacactcc ccctggtcgt gggcgtcgac ggatcggacg
    13981 cgagcctgct ggccgtcgac tgggcggtgg acgaagccgc ccgcggtgac catccgctgc
    14041 ggttggtgta cgcctcgctc tgggagcgct acgagggcgc cgtaccgtcg accggaggtg
    14101 aacgcccctc cgagcgcgtg ctggccgagc acatcgtggc gtcggccgcc gaacgcgccg
    14161 cactgcgccg gcccgatgtg ccggtgacga ccggcgtcgt cccggcggat ccggtcgacg
    14221 ccctctgcac gagggcaaca acgccttcgc cctggtgacg ggcgagcgcg gccgcggcga
    14281 gctcaaggga ctgctcctcg gatcggtgag cctgggcgtc gccgcccgcg cgcactgccc
    14341 ggtgatcgtg gtccggggcg acgagacagg actggtcggc ctgcacgagc agatcctctt
    14401 cggcgccggc gacctggcca ccggcgtgca ggccgtgcgc ttcgccctgc gcgaggccga
    14461 ggaacgcggc tgcgccgtgg acgccgtacg cgcctggcgt cggcccgcac tggagggcgc
    14521 ggccgtgttc accgaggacg ccgcgcagga gcccgaggaa cgagcggcgg cccagctcgg
    14581 tgaactgctg ggcgaggcca tggccgaagg tcccggcgtc ctggtacgcc ggaccacggt
    14641 cgagggtccg gccccccgga tcctcgtgga ccgctcggca gacgccgacc tcgtcgtcat
    14701 cggagcgcgc caccggcacg gccacttcgg cctgcaactc ggccacgtcg gccacaccct
    14761 gctgcaccac gcgcactgcc ccgtggcgat cgtgccgcag atgacttgaa cgtccccgac
    14821 acatcaggtg cccggcatgg ctgtgcgtgg ccggaagtct caccggcctc gttgccgggc
    14881 acctgacgcc gttgttgaag tcccctccgg cttctcaccg ttgggctcag gcctcgccaa
    14941 ccagcttctc cgggtcccga tgaccgtgga gaaggtggga atcacacaca ccaagggatg
    15001 tctctgttcc ggtggtggct cccaacgtgc ctccgtcgcg cgggacttcc cttcggccaa
    15061 cggttctcgg gctcaggacg tattgagatc ggcgttccgc tcaagctcgt tcagccacgg
    15121 ccggtgctcc gagttcatgg aggtcatcgg agtgacggaa gtcaagacgg caaaagcccc
    15181 ggtcacacag cggccagcgc agttgaggag gacggccgca gcgcacccga ggactgaccc
    15241 cgtcgccacc accggctgag cccagcgggc gcctctcgcg cccgctcccg gacggtcgtg
    15301 tcggggcgtt ctcgcggacc ggttcatgcg tgaccatgaa gggagatccg gcgggcacac
    15361 cgaaggagcg gaccatgagc agtctcgacc tcctgtccga ggacgagcgg ttcgtcgtca
    15421 ggacggtgcg cgacttcgtg gacaaggacg tcaaacccgt cgtccgggaa ctggagcgca
    15481 ccgacacata ccccgaagcc ctcatcgagc ggatgaagga actcggcgtc ttcggactcg
    15541 ccgtcccgca ggaatacggc ggcacccccg tctccatgcc ctgctacgtc ctcgtcaccg
    15601 aggagctggc ccggggctgg atgagcctgg ccggcgcgat gggcgggcac accgtcgtcg
    15661 ccaagctgct gctgcacttc ggcaccgagg agcagcggca gcgccatctg ccccggatgg
    15721 ccaccggcga gacccgcgcg acgatggcac tgaccgagcc cggcgggggc tccgacctcc
    15781 aggctatgca caccgtcgcc cgcagggagg gcgacgggta cgtggtgaac ggtgcgaaga
    15841 cgtggatcac caactcacgc cgctcgcaac tcatcgccct gctgtgcaag accgacccgg
    15901 acgccgagcc cgcgcaccgc ggcatgtccg ttctcctcgt cgggcacgga ccgggcctga
    15961 ccgtctcccg tgatctgccc aagctcggct acaagggcgt cgagagctgc gagctgtcct
    16021 tcgagaacca ccgcgcaccc gctgacgcgc tgctcggggc agtggagggg cacggcttcg
    16081 cccagatgat gcgaggtctg gagaccggcc gtatccaagt cgccgcccgc gccctcggcg
    16141 tgggccgggc cgcgctggag gacgcgctca cctacgcgca gcaacgcgaa tccttcggca
    16201 agccgatctg gcagcaccag tccatcggca accacctggc ggacatggcg acttcgctca
    16261 ccgccgcacg ccagctcacc ctctacgccg cccgtcgggc ggaggccgga caccgggtgg
    16321 acatggggag gccggcatgg cgaagctctt cgcctccgag acggccatgc agatcgccct
    16381 caacgccgtc cgcatccacg gcggctacgg ctactcgacc gagttcgacg tcgagcgcta
    16441 cttccgggac gcgcccctga
//
