LOCUS       reptomyces_RBGC_499109 16164 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_499109
VERSION     Streptomyces_RBGC_499109
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_004187715.1
  ORGANISM  GCF_004187715.1
            .
FEATURES             Location/Qualifiers
     CDS             2..2433
                     /protein_domains="PF07228"
                     /protein_domains="PF08447"
                     /protein_domains="PF13185"
                     /protein_domains="PF13581"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331723"
                     /pseudo=False
                     /translation="MSDRALTFAAAGLAAVYVPGTGSEELRLVETAGCAPSRYRLPESL
                     PLSGDSPAAHAFRTDRPVWLNSAELASCSEGGPTPRPSEASLGALPLRTGSTRLGCLVV
                     LGSSAGGFDAEQRRFLERYADAVVGVLQAGTDRATPSSLLSPALRSLRVGSFVLVPDTG
                     LIEADETLLELVGIAPDDFDGKAETLLAHALPEDMHALMSVLEPSTQPSVRRELEFRVR
                     CSTGEIRWLSLSSRVVASTDDRPEQVLGVVTATSVQRRGDDDVSRIQWLTAALDDAATV
                     RDVSGVMVTALREPLGADRVALADLQDDRLMVTVLDPPQPAAWPEMWRPQWRSEWPDAP
                     VSALPTLQLALRDGRVDLWPAGTAFEPGLAGIGTGGLAVLPLPAKGRVAGVCLVGWDRP
                     HEFLPEERSLLTATAALVGQALKRAHEHDAEQELATMLQRSLLPRRLPQLPGGTAVARY
                     LPARRGLQVGGDWYDVIDLSGERVALVIGDVQGHSAGAATIMGQMRTAVRAYAVEGHPP
                     DVVVSHANRLLVGMETDLFATCCYAELDMEEGNVLFVRAGHLSPLIRHPDGRSEEVHVE
                     GGPPLGIIAEAEYPMTACALAPGTVLALVTDGLVEAADLPLDEGLERTRTALGAADPAD
                     PGRMADELLGDIGRREDDVALLLLRYDGMKTRPIRAGWAVWRLPDAVMHARRFTARTLR
                     RWKVGEGADVVLLVVSELVTNALVHTAGPVHLDLMLRGDRVRVSVSDASPRAPAKPVIV
                     DWESTGGRGLLLVEAMSESFGSVPVAGGKQVWSEIVVPRHEPAPSDSGLPTERGGLP*"
     CDS             2431..3512
                     /protein_domains="PF13407"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331724"
                     /pseudo=False
                     /translation="MSTRVGRAVAALVAGLMTMSLAACGGQGEAGTDSFSVGLLLPSRA
                     VPRWEHADKPLIEQRLKQLCPRCTMEYANAENDATRQRQQMMSMITKGVRVMILDAADT
                     RALRSSIQEAHEAGVQVIAYDRLAEGPISGYVSFDGGQVGRLQGEALLTAMGGRADGGS
                     VVMMNGDPTSPNAEWFRRGALSVLKDMVKIGRSYDTVDWSTDIAHANMAAAVAALGPDR
                     IGGVLAANDTIAAGVISALKKAGVKDLPPVTGQDADLAAVQRIVKGEQYMTVYKPFRAE
                     AAAAAAMAVALGRGEGLREVATTTTDSPTMKHIPSVLLSPRAVTVGNIKQTLVEDGVYT
                     IDQICTREIRPACERAGLVP*"
     CDS             complement(3527..4542)
                     /protein_domains="PF05231"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331725"
                     /pseudo=False
                     /translation="MTVARHEQLRRGGVTALEICVVAGLYYGSAKLGLFQQLVRGQVTP
                     LWPPTGVALAGLLLRGPRIWPGIALGAFLVNISLGPSIPAVLAIVAGNTLAPVGSYILL
                     RRTGFRIEMDRLRDALALIFLGAFTGMLISATTGSGTLFLAGVLSADEFWPTWSVWWTG
                     DAMGVLVVAPVLLVLRSAHWPKNVRPSRWVEGLLLVVAAVCVGFLEISSVPLLFLGFPL
                     LIWAAFRFQLAGAAPCALAVSTFAIIAAARGSGPFADHDLLTNMITLQAFNGSASLTAL
                     LLGAAVSERNQAHKEIERACAQLADLVTEIAAGRRRPTLPDGGGGKEKKGGRTPRPA*"
     CDS             4819..5102
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331726"
                     /pseudo=False
                     /translation="VGVGGLRELAASFVAPGPSGVAIRTRLKQLAPVDEEVLRRVGAHL
                     GTLASRDLKARCRDGLGHDAEAWAVRKRELTPASASRWAGAITKASHDQ*"
     CDS             5100..5704
                     /protein_domains="TIGR01766"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331727"
                     /pseudo=False
                     /translation="VSSGTPLPARPHPVLTRLLHWAKACGVTAIAVEDLDFTAEKTREK
                     HGRRKRFRQLISGMPTGRLRARLTSMADHSGIAVIAVDPACTSRWGAEHWHKPLTGNIR
                     RTTRHDAAAVAIGRRAQGHPIRLGVPPRPLRHWGRTTPSRAHQSDVHRHRTVQADRRAL
                     GQEGPRPRIPGPRTRSVSPDAERTRATRTSNTVRDAPQ*"
     CDS             complement(5768..7101)
                     /protein_domains="PF07228"
                     /protein_domains="PF13185"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331728"
                     /pseudo=False
                     /translation="MAGEKGGKRSRLPHLPDLHVRLRAELGRIDEELRSLLAAMDRLQG
                     LLDAVVAISREVELPAVLHRIVTTAMDLVGARYGAMGVLNESGECVEQFIAAGLSEQER
                     ADLAGTDFPRGLGVLGHLIRHPEPLRVDNISAHPSSVGFPPGHPHLRTLLGVAISVRGE
                     IYGDLYLSERLDGRPFDAHDENVVVALASAAGIAIENVRLFEQVRHGAEQFQRLLLPTL
                     PDLRPFTAAAVYRPAAEPSRLGGDWYDAVPLPENVVAVVIGDVVGHDLHAAAAMASTRN
                     MLRALLFDRGNPPGAILAQLDRTLQAITHNPVTTTTLARIEPERPGWRLHWSTAGHVPP
                     LLITPERGAEYLFAEPGLPLGVDPEQPRPDHSHFLPQEATVVFFTDGLIEHPDHPIDES
                     LNELAQLAIGYAALPLQEFVQALADHHPSDGHDDMAVLALRTPQA*"
     CDS             complement(7102..7268)
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_7331729"
                     /pseudo=False
                     /translation="MYRSSEGLYERTAPAESGASCNATAVAADAPFTTTGTDHHEPDAG
                     ETEHQATRRL*"
     CDS             complement(7253..7398)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MEYVSTLGHVDADRIVSLAEQSPLPCSAMSICASSDRIVSGGRNV
                     PLK"
     CDS             complement(7513..8456)
                     /protein_domains="PF00067"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331730"
                     /pseudo=False
                     /translation="MTNRHFGPPHSPHRVDGMRGELHDIVAGLIDGIGDPGRIDLVDQF
                     SYPFPVTVICRLLGVPREDEARFHTWADTIAASLDPDPDADPAERGKDSHDARMQLGMY
                     LAGLIEERRKSPRDDMLSELATAKGPDGTMTTMELLSTAALLLIAGHETTVNLVTNGML
                     TLLRNPDVLRRLRADPRLAVPIVEELLRFEPPVQLLPQRTTLADIEVHGVTIPKGASLW
                     LVLASGNRDPQRFEDPDRFDPDRRDIQHLGFGSGIHICFGAPLARLEAQLALSELARRL
                     DNPRLLEDPPPYRQNAVLRGPRHLPIACDGIRP*"
     CDS             complement(8762..10152)
                     /protein_domains="PF07992"
                     /protein_domains="PF14759"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331731"
                     /pseudo=False
                     /translation="VNGDGFLDRFKREGRIVIVGASLAGLRAAETLREKGFAGSLTMIG
                     DEPYEPYDRPPLSKQVLLGMATADRTALPRRRALDATWRLGVPATGLDMAAKRVRLADG
                     DEVPYDRLLIATGVRARPWPREDEAALDGVFVLRTRDDGAALARRLSEGPKRVFVIGAG
                     FTGSEIASACRERGLPVTVAERAAAPLVGALGGVVGSVAAEIQRERGVDLRCGVMVTAL
                     EGDASGRVRAAHLSDGSTVETDVVIVSLGATRNTEWLAGSGLGAGPRGIACDAGCRAFD
                     IRGIVTDDIFVAGDVARSPHPLFGYQFLSLEHWGNAVSQAEIAAHNMLSESADRLPHMW
                     VPAFWSSQFGVNIKSVGVPSLGTEIIISQGSLTDHRFIGVYGYQGRVIGAVAFDQARWL
                     SFYQELIETTAPFPPPFPTVDRRPDGQRPMDPDFPDPSVPTHGPTVTLSGYSPADRRMT
                     FTPAH*"
     CDS             complement(10143..10387)
                     /protein_domains="PF13370"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331732"
                     /pseudo=False
                     /translation="LERTYPLVRLAVDLNRCQGYAQCAFLAPEVFVMHGEEGLLYHPEA
                     DEAQREKLAQAAAACPVQAILVDAVDAPAEAVSGER*"
     CDS             complement(10476..11083)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331733"
                     /pseudo=False
                     /translation="MWQKHERLWTPRAAGIAGVVFAVLMAAAIVLVRIALPGGAGGDDI
                     AVDAGQRSAVQTALALLPFAGIAFLWFMGALRAQAGEGEDRFVSTVFLGSGLVFVATLF
                     GSAAAAGSQQHSPFGRHFAYVLLTTYALRMAAVFIFTTSTIGRRIGAFPRPLVVFGYLA
                     GLTLLVAGADLPWSELVFPAWALIVSLHMLGGRRPAAPA*"
     CDS             11267..12090
                     /protein_domains="PF03358"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331734"
                     /pseudo=False
                     /translation="VAAAVAGPEDGSRCAAVNVTVVGVLREDHVTASSSVADVPPARYD
                     DLRALVVNCTLKRSPEPSNTQGLIDRSTAIMDAQGVRVDVLRAVDHDIATGVWPDMTEH
                     GWRTDAWPQLYEQVMAADILVLAGPIWLGDNSSVMKKVIERLYACSSLLNDRGQYAYYG
                     RVGGCLITGNEDGVKHCAMNVLYSMQHLGYTIPPQADAGWIGEAGPGPSYLDPGSGGPQ
                     NDFTNRNTTFMTWNLLHLARALKDLGGIPAYGNQRTAWDAGCRRDYENPEHR*"
     CDS             complement(12116..13011)
                     /protein_domains="PF01408"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331735"
                     /pseudo=False
                     /translation="VTAAPAAWNDSPVQVGLVGAGPWARAMHARMLAAGPETRLTAVWA
                     RRFDAARETAAPYGARAVASFEELLDNCEAVARVPLPSACEAPPARAAKAGKALLLEKP
                     LGPDLPSAQRLADAIDEAGVVSQLVLTKRYHPITREFISAARQVDVAGARSCYLHGAFL
                     GGDFATTWRLEQGALLDLGPHLLDLLDAAVGPIAHVRGTGDPRRWIELTCEHTNGAVSQ
                     ASLSGSVRLPQVITRIELFGPHPGLVYDTAELDHDECWPVLRREFATAVRTGTSTELSA
                     RRGLHLQRLIAQATQTD*"
     CDS             complement(13046..14259)
                     /protein_domains="PF00480"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331736"
                     /pseudo=False
                     /translation="MGEHLMTPNQVSAGELLQLIRSGRANTRADLQSATGLSRSTVGQR
                     LDLLNRAGWLRHTTGNSTGGRPSHRIVFDPGHASVIAVDLETRHARAAVLDLAGTILAE
                     HTAPLNINEGPDQVLDHLATWFPDLIAAAGIEPTHVCGIGLSVPGPVDWETGRVVEPPI
                     MPGWHQYPIRERLQKAYADHVGPSMEDGPVPVFVDNDANLMALAEHQANHPDCSAFVLV
                     KVSTGIGAGVVVGNGVYRGVDGGAGDIGHIRLHDRPDALCMCGSYGCLAAVASGRALAR
                     ELSALGLETTSGSDVRRLLTEGHPDAIRLARDAGRRAGEVLVTVVTLLNPGVLMLAGDL
                     SGVPFMTGVRELLYQRAMPRTTANLQIVTSRLGDHAGLIGAAAMVVEILYSPARAEARL
                     NAHIG*"
     CDS             complement(14265..15148)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331737"
                     /pseudo=False
                     /translation="VTRKAALSRAQFEERFFGVLRWFVIAFLAVITVLPFYYMVLLSVK
                     PIDALLLDPGSLWVSAKDFTVSTYRDVLRSTDSGGQGFVKFLLNSALVSLGTVLLTLLA
                     AVPGAYAISRLKFFGHRQVSALFLAVYMFPATLLAVPLFVIFAKMGLSSSLVGLAIVYV
                     AQTVPVSIYMLRNYLVTIPYSIEEAAAIDGCTRLQTVRKVILPLALPSIMATGLYVFMI
                     AWNEFLFALLFLAAEPGKWTVSLGLAQLSNGIEVPKTILMAGSVVLTIPVVLLFFAAER
                     LLTEGLTSGADKS*"
     CDS             complement(15146..16164)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7331738"
                     /pseudo=False
                     /translation="MTTAPPGAPQRRATSPRSTDRPAHRRGRPMTASRRANRAGLAFVS
                     PTFLVVLVVVILPILWTVLLAFQDAKLVDIQGMGLFGNWSLDNFAQIFGSAGFWSSLGT
                     TLIYTAGATAGSVVLGLIAALALRKPFRGRGLLRAAMLLPYVAPVVAVAFVWEVALSPQ
                     YGVVNDWGRRLFGWDDPIAFLSTREYEVSLLGMHFDIPLALLTVIAFECWRYFPFAFLF
                     ILARLQAVPHGLEEAALVDGATHTQRFRYVLLPQLMPVIALLCVLRFILTFNKFDDVYL
                     LTGGGAGTDIAAVRVYDFLTARYDVGAAAAQALVLAVSLMILLGFYFKFFGNKVQEES*
                     "
ORIGIN
        1 atgagcgatc gggccctgac gttcgccgca gcggggctgg cagcggtcta tgtgcccggt
       61 accgggagcg aagagctgcg gttggtggaa acggccggat gcgccccttc ccgttaccgg
      121 ctgccggagt ctttgcccct gtccggtgac tcacctgcgg cgcacgcctt ccgaaccgac
      181 cggcctgtgt ggctgaactc cgccgaactc gcctcctgct ccgaaggcgg gccgacaccg
      241 cggccgtcgg aggcgtcgct cggcgcgctg ccgctccgga cggggagcac gcggctgggc
      301 tgcctcgtcg tcctggggag ttccgcgggc ggcttcgatg ccgagcaacg gcgattcctg
      361 gagcgctacg ccgacgccgt cgtcggcgtg ctccaggccg ggaccgaccg cgccacgccg
      421 tcgtcgctgc tcagtcccgc cctgcggagt ctgcgcgtcg gctccttcgt cctggtgccg
      481 gacacgggcc tgatcgaggc ggacgagacc ctgctggagc tggtcggcat cgcgccggac
      541 gacttcgacg gcaaggcgga gaccctgctc gcgcatgccc tcccggagga catgcacgcg
      601 ctgatgtcgg tcctggagcc gtccacccag ccgtccgttc ggcgggagct ggagttccgg
      661 gtccgctgct ccacgggtga aatccgctgg ctgagcctga gcagccgggt ggtggcgagc
      721 acggacgacc ggccggagca ggtgctgggc gtggtgacgg cgacctcggt ccagcgtcgg
      781 ggcgacgacg acgtgtccag gatccagtgg ctgactgccg cactcgacga tgcggcaaca
      841 gttcgtgacg tcagcggagt gatggtcacc gcgctgcgtg agccgctggg tgccgaccgg
      901 gtggcgctcg ccgacttgca ggacgaccgg ctcatggtca ccgtgctcga cccgccgcag
      961 cccgccgcct ggccggagat gtggcgtccc cagtggcgtt cggagtggcc cgacgcaccg
     1021 gtcagcgcgc tgcccaccct tcagttggcc ctgcgggacg gacgcgtgga tctgtggccc
     1081 gccgggacag ccttcgaacc cggactcgca gggatcggca ccggaggtct ggccgtcctg
     1141 ccgctcccgg ccaagggccg ggtcgcaggc gtgtgtctgg tcggctggga ccggccgcac
     1201 gagttcctcc ccgaggagcg gtccctgctg accgccaccg cggcgctcgt cgggcaggcc
     1261 ctcaagcgtg cgcacgagca cgacgccgag caggaactcg cgacgatgct gcagcgcagt
     1321 ctgctgcccc ggcgcctccc ccagctgccc ggggggacgg ccgtggcccg ctatctgccc
     1381 gccaggcggg ggctgcaggt gggcggtgac tggtacgacg tcatcgacct ctccggggaa
     1441 cgcgtggcgc tggtcatcgg tgacgtgcaa ggtcacagcg ccggagccgc gacgatcatg
     1501 ggccagatgc gtaccgcggt ccgggcctac gcggtggagg gccacccgcc cgacgtggtc
     1561 gtctcccatg ccaaccgcct gctcgtcggc atggagaccg acctgttcgc cacctgctgc
     1621 tatgccgaac tggacatgga ggaaggcaac gtcctgttcg tccgggccgg gcacctctca
     1681 ccgctgatac gccatcccga cggccgtagc gaggaggtgc acgtcgaggg cgggccgccg
     1741 ctgggcatca tcgcggaggc ggagtacccc atgaccgcct gcgcactggc ccccggcacg
     1801 gtgctcgccc tggtcaccga cggcctggtc gaggccgctg acctgcccct ggacgagggt
     1861 ctggagcgga cgcgcaccgc gctcggtgcg gccgatcctg cggatccggg gaggatggcc
     1921 gacgaactgc tcggcgacat cggccgtcgt gaggacgacg tggcgctgtt gctgctgcgc
     1981 tacgacggca tgaagactcg gccgatacgg gccggctggg cggtgtggcg gctgcccgac
     2041 gcggtgatgc acgcccgccg tttcaccgcg cgcacactgc gtcggtggaa ggtcggcgaa
     2101 ggagccgatg tggtcctgct ggtcgtgtcc gaactggtca ccaacgccct ggtgcacacc
     2161 gccggtccgg tccacctcga cctgatgctc cgcggggacc gggtgcgcgt cagcgtgagc
     2221 gatgcctcgc cccgtgcgcc cgccaagccg gtgatcgtgg actgggagtc gaccggcggc
     2281 cgaggcctgc ttctcgtcga ggcgatgtcg gagtccttcg gctcggtgcc ggtggccggc
     2341 ggcaagcagg tgtggagcga gatcgttgtg ccccggcacg agccggctcc ctcggactcc
     2401 ggcctcccga cggaacgagg aggtctgcca tgagcacccg tgtggggcgt gccgtcgcgg
     2461 cgctcgtcgc gggactcatg acgatgtccc tggccgcctg cggaggacag ggcgaggcgg
     2521 gcacggacag tttcagtgtc ggcctgctgc tcccgagccg agcggtcccc cgctgggagc
     2581 acgccgacaa gccgctgatc gagcagcggc tgaagcagct gtgtccccgc tgcaccatgg
     2641 agtacgccaa cgccgagaac gacgcgacac ggcagcggca acagatgatg tccatgatca
     2701 ccaagggggt cagggtcatg atcctcgatg ccgccgacac cagggcgctc cgctcgtcga
     2761 tccaggaggc gcacgaggcg ggcgtccagg tcatcgccta tgaccggctc gccgagggcc
     2821 cgatctcggg ctatgtcagt ttcgacggcg ggcaggtcgg caggctccag ggcgaggcgc
     2881 ttctgacggc catgggcggc agggcggacg gcgggagcgt cgtcatgatg aacggtgatc
     2941 cgaccagccc caatgcggag tggttcaggc ggggcgcgct gtccgtactc aaggacatgg
     3001 tcaagatcgg caggtcgtac gacacggtgg actggagcac ggacatcgct cacgccaaca
     3061 tggccgcagc cgtcgccgct ctgggcccgg accgcatcgg cggcgtcctg gcggccaacg
     3121 acacgatagc cgcgggcgtc atctccgcgc tcaagaaggc cggtgtcaag gaccttccgc
     3181 ccgtcaccgg tcaggacgcc gacctcgccg ccgtgcaacg catcgtcaag ggcgagcagt
     3241 acatgacggt gtacaaaccc ttcagggcgg aagccgcagc cgccgccgcc atggccgtcg
     3301 ccctggggcg cggcgaggga ctccgggaag tcgccacgac gacgaccgac agccccacca
     3361 tgaagcacat cccgtccgtc ctgctctctc cgcgcgccgt gacggtcggg aacatcaagc
     3421 agacactcgt cgaggacggc gtgtacacca tcgaccagat ctgcacccgg gagatccggc
     3481 ccgcctgtga gcgggccggg ctcgttccgt aggaagaccc actgatcacg ccggtcgtgg
     3541 ggttctcccg cccttctttt ccttcccgcc cccgccgtcc gggagcgtcg gccggcggcg
     3601 gccggcggcg atctccgtca ccaggtcggc gagctgcgca caggcccgct cgatctcctt
     3661 gtgggcctgg ttgcgctcgc tgaccgcggc cccgagcagc agcgcggtca gtgaggcaga
     3721 accgttgaac gcctgcaggg tgatcatgtt ggtgagcagg tcgtgatcgg cgaacgggcc
     3781 cgatcctcgg gcagcggcga tgatcgcaaa ggtcgacacg gccagtgcac acggcgcggc
     3841 cccggccagc tggaagcgga aggccgccca gatcagcaac gggaagccta ggaagagcag
     3901 cggcacgctg ctgatctcca ggaagccgac gcagacagcg gccaccacaa gcagcaatcc
     3961 ctccacccaa cgggacggcc gcacgttctt cggccagtgt gccgagcgga gaacaagcag
     4021 gaccggcgcg accaccagga cacccatcgc gtcgccggtc caccagaccg accatgtcgg
     4081 ccagaactcg tcggcgctca gcacaccggc gaggaacagg gtcccgctgc ctgtcgtcgc
     4141 gctgatgagc atcccggtga acgcaccgag aaagatcagt gccagcgcgt cccgcaaacg
     4201 gtccatttcg atccggaacc ccgtacggcg gagcagtatg tacgagccga cgggcgcgag
     4261 agtattgccc gccacgatcg cgagcacggc cgggatcgac ggcccgagcg agatgttgac
     4321 caggaacgcg ccgagtgcga tgccgggcca gatccgcggg ccgcggagga gcaggcccgc
     4381 cagggcgacg ccggtcggcg gccacagagg ggtgacctgg ccgcgcacca gctgctggaa
     4441 cagccccagt ttggccgagc cgtaatacaa accggcaacg acgcagatct ccagggcagt
     4501 cacgccaccg cgccggagct gttcatgccg cgcgacagtc atggggcgac ctccgcatca
     4561 ccaccaccga agtccatcat cctccggatc ctccggctcc tccacggcac cgttgagcca
     4621 tggggtgggg aactgctggg atgggagtga gcaggagtgt gttctggtgt ggatgagtga
     4681 gcgctgacgc tcctgaccgg gggctgggtg ctgctcttgc gggaggagaa ggggagttcg
     4741 tctgtcgaat gggtgacctt tccgggtgac gctcgttggg gggaccgggt cttggcgggc
     4801 tggatgggga tgggggtgtg ggggtgggcg ggctgcggga gcttgcggcg tcgtttgtcg
     4861 cgcccgggcc ctccggcgtc gcgatccgta cccggctcaa gcagctcgcg cctgtcgacg
     4921 aggaggtgct gcggcgggtg ggcgcgcacc tgggaacgct ggcctcccgg gatctgaagg
     4981 cacgctgcag ggatggtctg gggcacgacg ctgaggcgtg ggcggtgcgc aagcgggagt
     5041 tgacgcccgc ctcggcctcg cggtgggcgg gagcgatcac caaggccagc catgaccagt
     5101 gagctctggc acgccgttgc cggctcgccc gcatccagtc ctcaccaggc tgctgcactg
     5161 ggccaaggcc tgcggtgtca cagcgatcgc cgtcgaagac ctcgacttca ccgcggagaa
     5221 gacccgcgag aagcacggcc gccgaaaacg gttcaggcag ctcatctccg gcatgcccac
     5281 cggccgcctc cgtgcccgcc tgacctccat ggccgaccac agcggcatcg ccgtcatcgc
     5341 ggtcgacccc gcctgcacca gccgctgggg cgccgagcac tggcacaagc ccctcaccgg
     5401 caacatccgt agaaccactc gccacgacgc tgctgccgtg gcgatcggac gacgcgccca
     5461 agggcacccg atccggctgg gggtacctcc caggcccttg aggcactggg ggaggacgac
     5521 accgtcccgt gcacaccaga gcgatgtgca caggcatcgg accgtccagg ccgaccggcg
     5581 tgccctgggg caggagggac cccgcccccg cattcccgga ccacggacac gatccgtgtc
     5641 gccggacgcg gagcgaacgc gggcgaccag gacatccaac accgttcggg atgccccgca
     5701 gtgaccaggc atgggtccaa gacccactcc tgctcactga tcaggaacgg tcggcagact
     5761 cggggctcag gcttgcgggg tgcgcagggc gagcacggcc atgtcgtcgt gaccgtcgct
     5821 gggatggtga tcggccagtg cttgaacgaa ctcctgcagg ggcagggcgg catacccgat
     5881 ggcgagctgg gcgagctcgt tcagactctc gtcgatggga tggtcgggat gttcgatcag
     5941 cccgtcggtg aagaagacca cggtggcctc ctggggcagg aagtgcgagt ggtcggggcg
     6001 gggctgctcg gggtcgaccc cgagcggcag cccgggctcg gcaaagagat attccgctcc
     6061 gcgctcaggg gtgatcagca gcggtgggac gtgccctgcg gtgctccagt ggagtcgcca
     6121 acccggtcgc tccggttcga tgcgcgccag ggtggtggtc gtgacgggat tgtgtgtgat
     6181 ggcctgcagc gtgcggtcga gctgggcaag gatcgcgccc ggcggattgc cccggtcgaa
     6241 cagcagagcg cgcagcatgt tacgcgtgga ggccatggcg gccgcggcgt gcagatcgtg
     6301 acccaccacg tcaccgatga cgacggccac aacgttctcg ggcagcggga cggcgtcgta
     6361 ccagtccccg ccgagtcggc tgggctcggc agcgggccga tagacggcgg cggcggtgaa
     6421 aggccgcagg tcgggcagcg tcggcagcag aagccgctgg aactgctcgg ctccgtgccg
     6481 aacctgttcg aacaggcgga cgttctcgat cgcgatgccg gcggcgctgg ccagggcaac
     6541 gacgacgttc tcgtcgtgag cgtcgaaggg ccgtccgtcg agccgctcgg agaggtagag
     6601 gtcaccgtag atctcgccgc ggacgctgat ggcgacgccg agcagggtgc gcaggtgcgg
     6661 gtggccgggc gggaacccga cggaggacgg atgggccgag atgttgtcga cccgcagagg
     6721 ctcagggtgg cggatcagat gcccgagaac acccagacca cgaggaaagt cggtcccggc
     6781 cagatcagcg cgttcctgct cggacaggcc ggcagcgatg aactgctcca cgcactctcc
     6841 ggactcgttc agaacgccca ttgccccata gcgggcgccg accaggtcca tggcggtggt
     6901 cacgatacgg tgcagtaccg caggcagctc cacctcccgg ctgatggcca ccacggcatc
     6961 cagcaggccc tgcagccggt ccatcgcggc gagcagggag cgcagttcct cgtcgatccg
     7021 tcccaactcg gcacgcagcc gcacatgcag gtcggggagg tgcggcagcc tcgatcgttt
     7081 ccctcccttc tctcctgcca tcacaagcgc ctggtggcct gatgttctgt ctcacccgcg
     7141 tccggctcgt ggtgatcggt gccggtcgtg gtgaacgggg cgtcggcggc cactgcggtg
     7201 gcattgcagg aggcgccgga ctcggcaggc gcggtccgct catacagccc ctcacttgag
     7261 cggtacattc cgtcctcctg acacgatccg atcactcgag gcacagattg acatggccga
     7321 acagggcaac ggcgattgct ccgcaagcga cacgatgcgg tcggcgtcga cgtggccgag
     7381 cgtggacacg tattccatgg tgcaccgacc gtcctcgacc tgaggggacg aagctgtcgc
     7441 agtgccctcg cgcgaaaggc cttcgaagcc ggcgccgccg gtcggccatg cacgccgccg
     7501 gggaagagac cctagggacg gatcccgtcg caggcgatgg gcagatgccg cggcccgcgc
     7561 agtacggcgt tctgccggta cgggggcggg tcctccagca gacgtgggtt gtccagcctg
     7621 cgggccagtt ccgacagggc gagctgggcc tccagccggg cgagcggtgc gccgaagcag
     7681 atgtggatgc cgctgccgaa gccgaggtgc tggatgtccc ggcggtccgg gtcgaagcgg
     7741 tccgggtcct cgaagcgctg ggggtcgcgg ttgccggacg ccagaaccag ccagagggag
     7801 gcgcccttgg ggatggtgac gccgtggacc tcgatgtcgg cgagggtggt gcgctgcggc
     7861 agcagttgca ccggcggctc gaagcgcagc aactcctcga cgatgggcac ggcgagccgc
     7921 ggatccgcac gcagccgccg caggacgtcg gggttgcgca gcagggtcag cattccgttg
     7981 gtgacgaggt tgacggtggt ctcgtgcccc gcgatcagca gcagtgccgc ggtgctgagc
     8041 agttccatcg tggtcatcgt gccgtccggg cccttggctg tcgccagctc ggagagcatg
     8101 tcgtccctgg gactcttgcg gcgctcctcg atcaggccgg ccaggtacat gcccagctgc
     8161 atacgggcgt cgtgcgagtc cttgccccgc tcggcgggat ccgcgtccgg atcggggtcc
     8221 aggctcgcgg cgatggtgtc cgcccaggtg tggaagcgcg cctcgtcttc gcgcggcacg
     8281 ccgagcagcc ggcagatcac cgtcaccggg aaggggtacg agaactggtc caccaggtcg
     8341 atccggcccg ggtcgccgat gccgtcgatc aggccggcga cgatgtcgtg cagctctccg
     8401 cgcatcccgt cgacccggtg gggggagtgc ggcgggccga agtgccggtt cgtcatgcgt
     8461 cgcagccggt cgtgttccgg cgggtcgagc cgaataaagc tcggcggcag ggcgctctcc
     8521 tcctcctggg ccgactcggc cagcgggtcg cgggcggtcg aggccagatt gcggacgtcg
     8581 gagctgaggc gggggtcgtg caggaggctg cggatctcgt agtacgtgcc gacgacgtaa
     8641 ggcccgtcgt cttcgtggtg gaccggcgtc ttccgcagct cttcgtagag cgggtacgga
     8701 tcggcgcggt tggcgtagtc caggatctgg cagcaggcgg ggtcctcgtg gccgtgcggg
     8761 tcagtgcgcg ggggtgaacg tcatccggcg gtcggccggc gagtatccgc tgagggtcac
     8821 agtggggccg tgggtgggga cagacgggtc ggggaagtcc gggtccatcg gccgctgtcc
     8881 gtccggacgc cggtcgaccg tggggaacgg cggcgggaac ggcgcggtgg tctcgatcag
     8941 ctcctggtag aacgacagcc accgggcctg gtcgaaggcg accgcgccga tgacgcgccc
     9001 ctggtacccg tagacgccga tgaaccggtg atccgtgagc gagccctgcg agatgatgat
     9061 ctccgttccc agcgacggca ccccgaccga cttgatgttc acgccgaact gtgaggacca
     9121 gaacgccggt acccacatgt gggggaggcg gtcggcgctc tcgctgagca tgttgtgcgc
     9181 cgcgatctcg gcctgggaga cggcgttgcc ccagtgctcg agggaaagga actggtaacc
     9241 gaacaagggg tgcggggagc gggcgacgtc gcccgcgaca aagatgtcgt cggtcacgat
     9301 tccgcggatg tcgaaggcgc ggcagccggc gtcgcaggcg atgccgcggg ggccggcccc
     9361 aagtccggac ccggcgagcc attcggtgtt tcgggtggcg ccgagcgaga cgatcacgac
     9421 gtcggtctcg acggtggagc cgtcggacag atgcgcggcg cgcactcgtc ctgaggcgtc
     9481 gccctccaga gcggtcacca tgaccccgca ccgcaggtcc acaccgcgct cgcgctggat
     9541 ctcggcggcg accgagccga ccaccccgcc gagcgcgccg accaggggcg ccgcggcacg
     9601 ctcggcgacg gtgacgggga gaccgcgttc gcgacaggcg gaggcgatct ccgagccggt
     9661 gaatccggcg ccgatgacga agacccgctt ggggccctcg gagagccgtc gtgcgagcgc
     9721 ggcgccgtcg tcgcgggtcc gcagcacgaa gacgccgtcg agtgcggcct cgtcctcacg
     9781 cggccacggt cgcgcccgca caccggtggc gatcagcagc cggtcgtacg gcacttcgtc
     9841 gccgtcggcc agccgcaccc gcttggcggc catgtccagg ccggtggccg ggacgccgag
     9901 ccgccaggtc gcgtcgaggg cgcggcgcct gggcagtgcg gtgcggtcag cggtggccat
     9961 gcccagcagc acctgcttgg acagcggggg tcggtcgtac ggctcgtagg gctcgtcgcc
    10021 gatcatcgtc agggaaccgg cgaagccctt ctcgcgcagg gtctccgcag cccgcaggcc
    10081 ggccagcgag gcgccgacga tgacgattcg gccttcgcgt ttgaacctgt ccaggaatcc
    10141 gtcaccgttc accggacacc gcctcggccg gtgcgtccac cgcatcgacg aggatggcct
    10201 ggacggggca ggctgcggcg gcctgtgcca gtttctcgcg ctgtgcctcg tcggcctccg
    10261 ggtggtacag cagcccctcc tcgccgtgca tgacgaagac ttcgggcgcg aggaacgcgc
    10321 actgcgcgta tccctgacag cggttcaggt cgactgcaag cctcaccaag ggataggtcc
    10381 tctccaacgg cccggtcccc ctgcgaccat cctctgcggc cggaggggat gcggcgacga
    10441 ggaggagacc gttggagtga gcgctgtggc cggctcaggc cggggcggcg ggacgccggc
    10501 cccccagcat gtgcaggctg acgatcagcg cccaggctgg gaagacgagt tcggaccagg
    10561 gcaggtccgc tcccgccacg agcagcgtca ggcccgcgag gtagccgaag acgacgaggg
    10621 ggcgagggaa ggcgccgatg cggcggccga tggtcgaggt cgtgaagatg aacaccgccg
    10681 ccatgcgcag agcgtacgtg gtcagcagga cgtaggcgaa gtggcggccg aacggcgagt
    10741 gctgctgact ccctgccgcc gcggcactgc cgaacagggt ggcgacgaag accagtccgc
    10801 tgcccaggaa cacggtggac acgaaccggt cctctccctc accggcctga gcgcgcaggg
    10861 ctcccatgaa ccacaggaag gcgatcccgg cgaacgggag cagcgccagc gccgtctgca
    10921 ccgcgctccg ctgcccggca tcgacggcga tgtcgtcccc gccggccccg ccgggtaggg
    10981 cgatgcgcac caggacgatc gccgcggcca tcaggaccgc gaagacgacc ccggcaatcc
    11041 cggcggcccg gggtgtccag aggcgctcgt gcttctgcca catggtccct cgctttctgc
    11101 ccgcacttct tgcgtacaga cagcagcaat ccacgaactc gcgccaccgg ggccgctcgg
    11161 gagacgtgat caccacccac taccgcgcgg ccataaggag gtcgcggcag acggtccagg
    11221 cgggcggccg ccggctgagc gaggggttcg ttcggaggca ctgctgtggc ggcagccgtg
    11281 gcagggccag aggatggaag ccgatgcgcc gctgtgaacg tcacggtggt gggggtttta
    11341 cgggaggacc atgtgaccgc ttcgtcatcc gtcgccgacg taccgccggc ccgctatgac
    11401 gacctacgtg ccctggtagt caactgcacc ctcaagcggt caccggagcc gagcaacacc
    11461 cagggactga tcgatcgcag caccgccatc atggacgcac agggcgtgcg ggtcgacgtc
    11521 ctgcgggccg tcgatcacga catcgccacc ggcgtctggc ccgacatgac ggagcacggc
    11581 tggcggaccg atgcgtggcc gcagctgtac gagcaggtca tggcggccga catcctcgtg
    11641 ctggccggcc ccatctggct cggtgacaac agctcggtga tgaagaaggt gatcgagcgc
    11701 ctctatgcgt gttccagcct cctcaacgac cggggccagt acgcgtatta cggacgtgtc
    11761 ggcggctgtc tgatcacggg gaacgaggac ggcgtcaagc actgcgccat gaacgtcctc
    11821 tacagcatgc agcacctggg ctacacgatc cctccccagg cggacgccgg atggatcggc
    11881 gaggcggggc ccggcccctc ctatctcgac cccggctcgg gcggcccgca gaacgacttc
    11941 accaatcgca acaccacctt catgacctgg aaccttctgc acctggcccg ggcgctgaag
    12001 gacctcggcg gcatccccgc ctacggcaac caacgcaccg cctgggacgc cggctgccgc
    12061 cgcgactacg aaaaccccga gcaccggtag gcgaaccccg gcgacggcat cgccctaatc
    12121 ggtctgcgtg gcttgtgcga tcaggcgctg cagatgcagt ccgcggcggg cgctgagttc
    12181 ggtactggtg cccgtgcgta cggcggtggc gaactcgcgg cgcagcacgg gccagcattc
    12241 gtcatggtcg agttcggccg tgtcgtagac gagtccgggg tgcggaccga agagttcgat
    12301 ccgggtgatc acctggggga gacggaccga tccggacaac gacgcctggc tgacggcgcc
    12361 gttggtgtgt tcacaggtga gttcgatcca ccggcgaggg tctccggtgc cgcggacgtg
    12421 ggcgatggga ccgacggcgg cgtccaggag atccaggagg tgcgggccga gatcgagcag
    12481 cgcgccctgc tcgaggcgcc acgtggtggc gaagtcgccg cccaggaatg cgccgtgcag
    12541 gtagcaggag cgtgctccgg cgacgtccac ctggcgggcg gcactgatga actcgcgcgt
    12601 gatggggtgg tagcgcttgg tcagtacgag ctgggagacc acgccggctt cgtcgatcgc
    12661 gtcggcgagc cgctgagccg agggcaggtc gggtccgagg ggcttctcca ggagcagcgc
    12721 cttgcccgcc ttggcggcac gtgcgggcgg agcttcgcag gctgacggaa gcggcacgcg
    12781 agcgaccgcc tcgcagttgt cgagcagttc ctcgaaactc gccacggcac gagctccgta
    12841 cggcgcggct gtctcacgtg cggcatcgaa gcggcgcgcc cagaccgcgg tgagacgcgt
    12901 ttcggggccg gcggcgagca tacgggcatg catggcccgg gcccacggtc cggcgcccac
    12961 gagtccgacc tggaccgggc tgtcattcca cgctgctggt gcggcggtca cgggatgtcc
    13021 tgtctgtgcg gggggcgggc gctctcagcc gatgtgcgcg ttgaggcgag cctcggcccg
    13081 ggcgggggag tagaggattt cgacgaccat ggccgcggcg ccgatgaggc ccgcgtggtc
    13141 gccgaggcgg gaggtgacga tctgcaggtt ggcggtggtg cggggcatcg cgcgctggta
    13201 gagcagttca cgcacgccgg tcatgaaggg cacgccggac aggtcaccgg cgagcatcag
    13261 gacaccggga ttgaggaggg tgacgacggt gacgaggact tctccggcgc gccggccggc
    13321 gtcccgggcg agccggatgg cgtcggggtg gccctcggtc agcagccgtc ggacgtcgga
    13381 cccggaggtg gtttccaggc cgagggcgga cagttccctg gccagcgccc ggccgctcgc
    13441 gacggcggcc agacagccgt aggagccgca catgcacagg gcgtcgggcc ggtcgtgcag
    13501 acggatgtgg ccgatgtcgc cggcgcctcc gtcgacgccg cggtagacgc cgttgccgac
    13561 gacgacgccg gcgccgatgc cggtggagac cttgaccagg acgaaggcgg agcagtccgg
    13621 gtggttggcc tggtgctcgg cgagtgccat gaggttggcg tcgttgtcga cgaagacggg
    13681 tacggggccg tcctccatgc tgggcccgac gtggtcggcg taggccttct ggagccgttc
    13741 ccggatgggg tactggtgcc atccgggcat gatgggcggc tcgacgaccc ggccggtctc
    13801 ccagtcgacc gggcccggta cggacagtcc gatgccgcag acgtgggtcg gctcgatgcc
    13861 ggcggcggcg atcaggtccg ggaaccaggt ggcgagatgg tccagtacct ggtccgggcc
    13921 ctcgttgatg ttcaggggcg cggtgtgctc ggcgaggatg gtgccggcga ggtcgaggac
    13981 ggcggcacgg gcgtgccggg tctccagatc gacggcgatg accgaggcgt ggcccgggtc
    14041 gaaaacgatg cggtgggagg ggcggccgcc ggtggagttg ccggtggtgt gccgcagcca
    14101 cccggcgcga ttgagcaggt ccaggcgctg gccgacggtc gaccgggaca gcccggtggc
    14161 gctttgcagg tcggcgcggg tgttggcgcg gccactgcgg atcagttgca gcagttcgcc
    14221 cgcgctgacc tggttcggcg tcatcaagtg ttcccccatg gattcagctc ttgtcggcgc
    14281 cgctggtcag gccctcggtg agcaggcgtt cggcggcgaa gaacagaagt accacgggga
    14341 tcgtcagcac cacggaaccg gccatcagga tcgtcttggg aacttcgatg ccgttggaca
    14401 gctgggccag ccccagggag acggtccact tgccgggctc ggcggccagg aagagaagcg
    14461 cgaacaggaa ctcgttccag gcgatcatga agacgtacag gccggtcgcc atgatggagg
    14521 gcagggccag cggcagaatg accttgcgga cggtctggag ccgggtgcag ccgtcgatgg
    14581 ccgccgcctc ctcgatggag taggggatgg tgaccaggta gttccgcagc atgtagatcg
    14641 acaccggcac ggtctgggcg acgtagacga tggcgagtcc caccaggctg gaagacagtc
    14701 ccatcttggc gaagatgacg aacagcggga cggccagcag ggtcgccggg aacatgtaga
    14761 cggccaggaa gagcgcgctg acctggcggt ggccgaagaa cttcagccgg ctgatggcgt
    14821 aggcgccggg cacggcggcc agcagggtca gcaggaccgt ccccagggac accagcgcgg
    14881 agttgagcag gaacttcacg aagccctgac cgccggagtc ggtggagcgc agcacgtcgc
    14941 ggtaggtcga tacggtgaag tccttcgccg agacccacag ggatcccggg tcgagcagaa
    15001 gggcgtcgat gggcttcacc gacagcaaca ccatgtagta gaaggggagg acggtgatca
    15061 ctgcgaggaa cgcgatgacg aaccaccgca ggacgccgaa gaacctctcc tcgaactggg
    15121 cccgggacag ggcggccttg cgggtcacga ttcctcctgg accttgttgc cgaagaactt
    15181 gaagtagaag cccagcagga tcatcagtga gacggccaga acgagcgcct gggcggccgc
    15241 cgctcccacg tcgtagcggg cggtgaggaa gtcgtagacc cggacggcgg cgatgtcggt
    15301 gcccgcgccg cctcctgtca gcaggtagac gtcgtcgaac ttgttgaagg tcaggatgaa
    15361 gcgcagcacg cacagcaggg cgatgacggg catcagctgg ggcagcagga cgtaccggaa
    15421 gcgctgggtg tgggtggcgc cgtccaccag ggcggcctcc tcgaggccgt gggggaccgc
    15481 ctggagccgg gcgaggatga acaggaaggc gaaggggaag tagcgccagc actcgaaggc
    15541 gatgacggtc agcagggcca gcgggatgtc gaagtgcatg ccgagcaggc tgacttcgta
    15601 ctcgcgggtg gagaggaagg cgatggggtc gtcccagccg aacaggcgtc ggccccagtc
    15661 gttgaccacg ccgtactgcg ggctgagggc gacctcccag acgaaggcca cggcgacgac
    15721 gggggcgacg tagggcagca gcatcgcggc acgcagcagg ccgcggccgc ggaagggctt
    15781 gcgcagtgcg agtgcggcga tgagtccgag gacgacggag cccgcggtgg cgcccgcggt
    15841 gtagatcagg gtggtgccca ggctggacca gaagccggcg gagccgaaga tctgggcgaa
    15901 gttgtccagg gaccagttgc cgaacaggcc catgccctgg atgtcgacga gcttggcgtc
    15961 ctggaacgcc agcagcacgg tccacaggat gggcaggatg accaccacga ggaccacgag
    16021 gaaggtgggg gagacgaacg cgaggcctgc gcggttggcg cggcggctgg cggtcatcgg
    16081 ccggccgcgc cggtgggcgg gccggtccgt ggaccggggg ctggttgcgc ggcgctgcgg
    16141 tgcgccgggc ggggctgttg tcat
//
