LOCUS       reptomyces_RBGC_562649 16648 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_562649
VERSION     Streptomyces_RBGC_562649
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000240165.1
  ORGANISM  GCF_000240165.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..630)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741866"
                     /pseudo=False
                     /translation="MRRVSYRSTDGSTRCGVVHDNTIHALGTNLLEQLRAEGGLQTAAT
                     REPTETVELATAHLPAPVPVPPAVRNITTFEHHISNTGKAAGGHGTVSPVWHEHPLFSF
                     SNPAAIKRPHDKIPIAPDARSWDYEVKAAAAESAVAVVTGTALATLATVLAAMTQHAPL
                     SGLVTAAPTVIPWPQIGGPSRSASSSPWPPRRPRPEVQAVGLRSRP*"
     CDS             complement(684..1801)
                     /protein_domains="PF06441"
                     /protein_domains="PF00561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741867"
                     /pseudo=False
                     /translation="VVIVTSNSVTPFRIAIPDSALEDLKDRLHRVRLAGRQTAPDNSQG
                     VQRERLEELLEYWATGYDWRKLERQLNELGQSRTTIDGLGIHFTHVRSPHPDATPLLLL
                     HGWPGPFLEFLGTVGPLTGHGFHLVIPSMPGYGFSDQPTSTGWGPDRIARAYGVLIQRL
                     GYDSYLAQGGDWGGVIATRMGAQRPAGLRAIHLNFPEFLAAPPVGDDPTPEEKAAPQQG
                     SRFLTVHSGYHVVQRTRPQTIGYALTDSPAGQATWIYEKFLDWTRPDALTPDEILDHIS
                     LYWYTGTGASSARLYWEYARQPLALTEPDLPVGVSVFPDELTRTPRIRAERANHDLRYF
                     TDDIPACGHFAALEQPELFVEEIVKFARTVTP*"
     CDS             2151..2866
                     /protein_domains="PF03466"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741868"
                     /pseudo=False
                     /translation="MARTRAASRPSSVTIGYTKGLIITPAVRALRDRDPGAEVNTRLLA
                     WNDSRGALLEHRVDAVVTRLLFPTGQLRVTVLYDEPRVLIVARDHRLAGKESVTLDDIV
                     DEPIPRVRRSDPLLNAYWRLDPRPDGRPAPDGPLLEALEDEHELIAAGQAVAIGPPPRL
                     RDRAASQPHHGPVARGRTEPGRARHPRRRPQPSGHRFPQTRRSSAHRNPPDRTGTHNMI
                     RGGSARPPTRAITARA*"
     CDS             3502..5582
                     /protein_domains="PF13245"
                     /protein_domains="PF01443"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741869"
                     /pseudo=False
                     /translation="LSKMNDPAVRAVDLEQDYVSSVYELLTERLCEARAHRASVLKAPA
                     GSPGEAYAREIAAERLAKEIGRLEGAEKGLVFGRIDWTDGTALRIGRIGLHTEEDDLPL
                     LVDWRANAARPFYEATPVHPMGLRRRRHLRLEERTVISVSDELLDGTAPTHDDIVGDGP
                     LTEALSARRTGRMHAAVATLQAEQDEIVRSAHRGVTVVQGGPGTGKTVAALHRAAYVLY
                     AFPRAAEEGVLVVGPNARFLDYICQVLPSLGENDVVLATCRELAGASTDTVDPFDTARL
                     KGGSGLADALAGLLRVHQAPAGDFTVRVGQELVHLSGEEVATARDAAVAAVAGHNPARQ
                     VFKELLADAVTDAMRRDMGDLLEQIDADAERMTGINLDRFTGAAQRRVEGAADPGPAHE
                     LDLDAVRADLLDDAGVDRAVEVLWPRLAPGDLVKALLTNAAALAEHLPRLTAHERSLLL
                     RGPDDPWTVADAPLLDEAASLVDGPPERTYGHVVVDEAQELTAMQWRMIVRRCPSRSMT
                     LVGDFAQAGPVATARDWKEALGPHAGPRFKLHNLTVSYRTTQEILASVRDLLTRIAPDQ
                     KPTRSLRSGENPRTVTTPPDGLVTAVVHELRAQSAAYPGELAGVICADTRVSELTAQGI
                     AHHARIVPASEARGLEFDTVVVLNPEEIITNRPGGERDLYVALTRATKRLCTITVQPA*
                     "
     CDS             complement(5409..6706)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741870"
                     /pseudo=False
                     /translation="MPHRPLSLSPARPTELRSRALLDEHGNATARGRQEREHIEDATNR
                     LAQRLLRPLREPDADRLLHTLTPAVRAITSCGVLPFPTRSDCPARTCPADRILGVPQSA
                     REPLAAGDSPARPGRDRQARYPHRLARRAGCAVSRTRHPVVRLWGWCDGSRLARRGQRP
                     GRPGARRRSGPQWPPGPDGRASPAGRCPRSPARSAAEAVFTDRTRSRLGRSHGVILPGA
                     MPNGPSTPCPCRPGADGRARSTSRSSRTASPCRSCHGRAAGRFPRKSSQSWRRSGCPGP
                     DRVLTHRAQRENRESRHGTTRRVRRTPGRQTAGAPVATWRWTRLAGLVPAPGIPPGYWS
                     RAVVEGLRCGPRWRAGRCLRRAGCARAATARVPGRQAGWTVMVQRRLVARVRATYKSLS
                     PPGRLVMISSGFRTTTVSNSRPRASDAGTMRAW*"
     CDS             6731..7062
                     /protein_domains="PF01979"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741871"
                     /pseudo=False
                     /translation="LPTFDAADLIAFATIEGARACGIDDRTGSVTPGKEADLIMVRLDH
                     TNLLPATDVAASIVAGGHAGNADLVVVAGEVLKEDGALVRGDSVFAEAAASRDRLFHAA
                     GLPLPS*"
     CDS             7449..8791
                     /protein_domains="PF02624"
                     /protein_domains="TIGR03604"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741872"
                     /pseudo=False
                     /translation="VAGDVLENLDGLLSPYGVAGGVRELPYAPGEPTVPAYGALAGHVL
                     RLLDADPFHRPGGPGGRPGASYDYSSAGTAQSPERARLLALAELLERYCATMAQDPGVV
                     VRASAVELGDEALDLGSLPRLSAQEYACAGQPLLPPDPAAPMRWVRGWSLTRRRPVYVP
                     AVIAWMGCAPQRPAERIWHPVSTGFAVHGDLRTAVMHALCECVERDMISTVWLRRLPLP
                     RLDIGRVSELGDAARVMLERYRRSVLADPVLFDATSDLGIPTIYLVGRAPHSSRAATMV
                     GCASGADPQQVLAKVLREVIAYRVALHVDHEVPAEVGDFQDVLDGAQWMGRPERADAFG
                     FLLSGERRARLSDMPVLARGDAAGDPDLVVGRLRERGMEAVAVDVTTDEARDVGFHAVR
                     VFVPQLVPLSFQQNGRYLGHPRLLDAPERLGYPECAGTDINPLPQPFA*"
     CDS             8892..9598
                     /protein_domains="TIGR03882"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741873"
                     /pseudo=False
                     /translation="VGVPPLHLVALDAWGEAVVPQPDRGVVVSAVSAAPRAGAGGRTVS
                     AAPATWPQAGCHVVACAREDVSFFRDVDTFCFLWSLTWAPLVLTPRGVRLGPVVVPGRS
                     ACYHCFLRRQRQHDWDVGDTQAWWDSVTRDPSNCVAGWLPSDVLMARGLTRVLAARGPG
                     AFAGTVVTYDGVTGDVSGDPVTGVHACPRCRRRPDRRADTWTALAQQFPPPSATACPPV
                     SAPVCPAGGEQAR*"
     CDS             9596..11736
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741874"
                     /pseudo=False
                     /translation="VKLPTRSVGAGTAARHLHRSPLPAVPRLPRLRHGIRFLRLPDGIQ
                     FDGGPEREVLRGTATRHLLPRLLPLLDGAHDVAALAEAAGSETGVIERLLALLHLRGLL
                     EEGAFVPGTPTALALSRLGATTWADAHAGQSVDRLAAARVALHGTAPLLSELAGALREA
                     GTGEVVTAGPQPCPADLAVVLLGPCGMAGDEAERLSAAYAREPVALLPWFVAGPVSVIG
                     PLLAPELDLCLGCLRRELADTGSTPPPGPADPWTAVHAALACREVLALLAHVPPAHSPD
                     GATRYDLEAWTTERAMPTAGPSCPVCRPRSAAEEASEPAACPGCTPAAGRLPGADVPSD
                     HLPTAGSSCPACHPRSAAEEACEPAPRPACVPAAHRPPDADVPAAHVPTAGSSCPACHP
                     RSAAEEACEPAACPGCVPAAGRPLDADPVSVAVRYHQAVAKPALHRVTPASRLQSLSRL
                     PAAVQERRRWPSAALVPLPALPAPGTPWRPAGPPGTSWGGAADAGTPRGPAGPPGIPWD
                     GAGAGAATAAKAPALGDLALLLGMTAGRRGAQGMDFWAPSGGNLGSPCLYLAARGIDGL
                     ADGCYGYDALAHALARLAGLPAVDLVPGPHAPSAVLVLTGDVPRIQGKYGPFALHLACL
                     DAGVALTQLETAAGLLGHRVTLHDDLPAPGVAALADAFLIDSGREPVTAVLSVTPHARD
                     RGEPPPSTGAAGPVHPQER*"
     CDS             11737..12503
                     /protein_domains="PF00881"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741875"
                     /pseudo=False
                     /translation="MADTFPLPATPQQLADGLLRAYAAGQPGAGGTVPPRLRPGLPAGT
                     APRHRLPPPAPPLRSLHAVLDERRTVRDFAATPLPDAVLAAVLAAAREHDARTAPGETR
                     AGNGLAPLVVARRVAGLTPAVYGTGPDPACLYRYGPLTSPAWHCLFADPQIAGAPVLVV
                     MAGSVAAACIRHGARGHLRLLRRAGSAVHAGWLAALQRGYGGVILGATLPSPELSATAR
                     LDPVSRRPLAALALGTPGPDPLPHPAAPSSAGR*"
     CDS             12579..12706
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_7741876"
                     /pseudo=False
                     /translation="MIEKENENAAEADEFLYAEVLEDTATSYSKGSSSCGFNPSGT*"
     CDS             12828..13396
                     /protein_domains="PF13302"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741877"
                     /pseudo=False
                     /translation="MRLPGAFTAIPTVTGDGVRLRAPRQEDLPGLVRAFSDERVRRFMP
                     VPCEYTAAHAQNFIDTAPAMWRAHRAVFVLADAASDTFIGEAELLSLNELYRSAEAAFL
                     LDAPARRLRTAVAGVRLLCRFGFEELGLTRIEAFTDLDNRAVHYVGAHAGFRKEGIARG
                     KIPGPGGQRRDCLVAALLPGDLAPQR*"
     CDS             13470..14416
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741878"
                     /pseudo=False
                     /translation="MAGPAIEAVRLTRTFGGSTAVDAFDLTVAAGTVVSLLGPNGAGKT
                     TIVRMLATLIRPTSGSARVCGHDITTRPQAVRSVISLTGQFTALEDTLTARENLLLMAR
                     LRGHGKRGAAKVTDWLVDRFELGAFRDQLVKTLSGGQRRRVDLAAGLVVQPRLLVLDEP
                     TTGLDPRSRETVWSTVRELVAEGVTLLLTTQYLDEADALSDHIVLLEHGRATASGTPAQ
                     LKRRVGHQRIDVTTADATGFTRLRAALAPRFTLTGVPERLLLQLPAPHAAQDLAAVSQA
                     VRDSGVPVEEIVLRSPTLDDVFLTLTGHPPKDRT*"
     CDS             14414..15267
                     /protein_domains="PF01061"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741879"
                     /pseudo=False
                     /translation="MTTPTPPRPAPPRPATHQRKALRRFRTWRYLRETALLVSRTLRVA
                     ARMPVRIGGVTLQPVVNTVLFVTVFGSAVHIPATRYPDYLLPGLIAQSVAFGGVSAGVA
                     TATDFSLGVIDRLTSLPITRLAVITAQIVGQVIEQAASMLVVACLGAALGWRPRVNADA
                     ICELAGLLLLGLFAFTTFGVLLGTIVRTPATIQGLGYGILLPLVFLGGTYVPVTGMQTL
                     PRTIAEYNPIAALVAAVRQVAQGTGSTGSLMLEHPVPSTAACCTLLIAVCLPLAVKKFG
                     PGP*"
     CDS             complement(15457..16340)
                     /protein_domains="PF00665"
                     /protein_domains="PF13276"
                     /protein_domains="PF13333"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741880"
                     /pseudo=False
                     /translation="VIDHLRDKGLGVDPVCRVLGLSPSTYFARKTRPKSARRLRDEELI
                     PLVTAAWEDSGRTYGARRVTRALVRAGHAVARCTVERLMRELGIEGVIRGQRRRTTVPE
                     PTAPRPPDLVNRRFTAERPNQLWLADLTYIRTWSGWVYVAFVLDAYSRRIVGWQAATHM
                     RTDLPLDALEMALWRQQIKKDAGLIHHSDRGSQYVSIRYTERLAEAGASASVGSVADSY
                     DNAMAEALNGTFKAELIEHQGPWRDFDEVERAVFQWVAWYNGERLHSALGYLPPDEYEQ
                     AYWARPEQVPQTA*"
     CDS             complement(16338..16648)
                     /protein_domains="PF01527"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7741881"
                     /pseudo=False
                     /translation="VPAPRKYPDELRERAVREVRSTGRPVTHVARDLGIHKEALRSWVR
                     QAEADAGERDDRLTSSELEELKQLRKENAELRRANEILKAASVFFAQEIDRPRTRPSR*
                     "
ORIGIN
        1 ctacggcctc gatcgcaggc cgacggcttg cacttcaggt cgcggccgac gcggtggcca
       61 gggcgacgaa gacgcagatc gcgacggtcc ccctatctgg ggccaaggga tcaccgtcgg
      121 agccgccgtc acgagcccgc tcaacggggc gtgttgggtc atcgcggcca gtacggtcgc
      181 caaggtggcg agggctgtgc cggtgaccac cgccacggcg gactcggccg cggcggcctt
      241 gacctcgtag tcccacgacc gcgcgtccgg ggcgatgggg atcttgtcgt ggggtctctt
      301 gatcgcggcc gggttcgaga aggagaagag cggatgctcg tgccagaccg ggctgaccgt
      361 gccgtggccg ccggctgcct tgcccgtgtt gctgatgtgg tgttcgaacg tggtgatgtt
      421 ccggactgcc ggaggcactg gtaccggcgc cggcaggtgg gccgtggcca gctcgacggt
      481 ctcggtgggt tccctggtcg cggcggtctg cagcccgcct tcggcgcgca gctgctccag
      541 caggttcgtg cccagggcgt ggatggtgtt gtcgtgcacc acgccgcagc gtgtggagcc
      601 gtcggtggag cggtagctga cccgcctcat cgggcaaggc cccccgggtg tagtggtgga
      661 gtcttcgtga tcccaactgt tctcacgggg tcaccgtccg ggcgaacttg acgatctcct
      721 cgacgaacaa ctccggctgc tccagggcgg cgaagtggcc gcacgcgggg atgtcgtcgg
      781 tgaagtagcg caggtcgtgg ttggcgcgct cggcccggat gcgcggggtg cgcgtcagtt
      841 cgtccgggaa gacgctgacg ccgacgggga ggtccggctc ggtcagggcg agtggctgcc
      901 gggcgtactc ccagtacagg cgggcagagg atgcgccggt gccggtgtac cagtacaggg
      961 agatgtggtc gaggatctcg tcgggggtga gggcgtcggg ccgtgtccag tcgaggaact
     1021 tctcgtagat ccacgtggcc tgcccggcgg gggagtcggt cagggcgtag ccgatggtct
     1081 gcggccgggt gcgctgcacg acgtggtatc cggaatggac ggtgaggaag cggctgcctt
     1141 gttggggtgc ggccttctcc tcgggggtcg ggtcgtcgcc gaccggtggc gcggcgagga
     1201 attcggggaa gttgaggtgg atcgcgcgca ggcctgccgg gcgctgcgcc cccatgcggg
     1261 tcgcgatgac accgccccag tcgccgccct gggccaggta ggagtcgtag ccgaggcgct
     1321 ggatgagtac gccgtacgcg cgggcgatcc ggtccgggcc ccagccggtg gaggtgggct
     1381 ggtcggaaaa gccgtagccg ggcatcgagg ggatgacgag gtggaagccg tggccggtga
     1441 gcgggccgac ggtccccagg aactccagga acgggccggg ccacccgtgg agcagcagca
     1501 ggggggtggc gtcggggtgc ggcgagcgca cgtgcgtgaa gtggatgccg aggccgtcga
     1561 tggtggtacg ggactggccc agctcgttga gctgccgctc cagcttgcgc cagtcgtagc
     1621 cggtggccca gtactccaac agctcttcaa ggcgctcccg ttgcaccccc tggctgttgt
     1681 ccggtgctgt ctgccggccg gccaggcgta cccggtggag ccggtccttc agatcctcca
     1741 gggcactgtc cggaatggcg atgcgaaaag gtgtcacgct gttcgatgtc acgatcacca
     1801 cggtgcggcc accacgggtt cgcggtccaa tgattgttcc gcaaaacgtc atacggggtt
     1861 tgcataatgc cagttagggt gggttgatgt ccgagccctt ccccgcgccc gtcgacctcg
     1921 acctgcggct ggtgcagtgc ttcacggtcg tcgccgagca ccggcatttc ggccgtgccg
     1981 ccgaggcgct gcacaccacg cagccgtcgc tgagccggca gatccgccgc ctcgaacagc
     2041 aagtgggcgt ccgcctgctc gaccgcacca cgcacgcacc cggctcagcg aggccggcga
     2101 gatcttcctg ccccgggcca aggggctgct gcgtgccgcg gtcgaggcga tggcccgcac
     2161 ccgggccgcg tcccggccca gcagcgtcac catcggctac accaaggggc tgatcatcac
     2221 tccggcggtg cgcgccctgc gcgaccgcga tcccggtgcc gaggtcaaca cccgcctgct
     2281 cgcctggaac gactcgcgcg gcgcgttgct ggagcaccgc gtcgacgcgg tggtgacgcg
     2341 tctgctgttc cccaccggcc agctacgcgt caccgtcctc tacgacgagc cgcgcgtgct
     2401 gattgtggcg cgggaccatc gtctggccgg caaggagtcg gtcaccctcg acgacatcgt
     2461 ggacgagccg atcccccgcg tacgccggtc cgacccgctg ctgaacgcct actggcgcct
     2521 cgatccccgg cccgacgggc ggcccgcgcc cgacggcccc ctgctcgaag ccctcgaaga
     2581 cgaacacgaa ctcatcgccg ccgggcaggc cgtggccatc gggccgcccc ctcgactacg
     2641 cgaccgggct gcatcccagc ctcaccacgg tcccgttgcg cggggtcgga ccgagccagg
     2701 tcgtgctcgc cacccgcgcc ggcgaccgca gccgtctggt caccgctttc cgcaaacacg
     2761 ccgaagctct gctcaccgga acccaccaga tcggaccggc acgcacaaca tgatccgcgg
     2821 cggctccgcc cgcccgccca cacgagcgat cacggcccgc gcctgatctg ccgccccggc
     2881 gccccggtga gaccgccgga ccggtccggg aacttcctcc gcaccgtcga actggacgac
     2941 gccgcgcggg ccgcgctcgg tctgggcgtg cccgacccgg tctccaccgt gttctccccg
     3001 gacgccgtat ccctcgcacc acaacgcgtc ctcgccggac acaccccgcg gaaaatcgca
     3061 cgccggctgt gtcggaatgc tccggcggat cgggccttag ccgccagtgg accctgttcc
     3121 cggccgtcat cggatttcat gggatctcct tggaccggag cccggaaaag accggtccat
     3181 cgggccccgc cgggcctgtc gtcattcttt cctacggcga catgaaagcg cggaggccgg
     3241 tgaccggcga atccaggccg ggcagtggtg aactcgatgg cgcggaaaga caccgccggc
     3301 gttcaagggc gggttcgccc ataaggcagg cgggcaccgg gagcgcgatt ggcgatgtac
     3361 ggaacggcgg aatgcgtgat acgccacacg gtcagccgtc acggattcag acgtaatgac
     3421 atggctcgcc aggtaagtca agacttacct ttcggaatcc ttggtcgtat ggtgtggctc
     3481 caatcgaagg agcctccctg ttgtcgaaga tgaatgaccc agctgtgcgt gcggttgact
     3541 tggagcagga ttatgtgtcc tccgtgtacg agttgctcac cgagcggctt tgcgaggcgc
     3601 gagcacaccg ggcgagtgtg ctgaaggccc cggcgggcag ccccggtgag gcgtacgcga
     3661 gggaaatcgc cgccgagcgt ctggcgaagg agatcggccg gctggagggc gccgaaaagg
     3721 ggctggtctt cggacgcatc gactggacgg atggcacggc cctgcgcatc gggcgcatcg
     3781 gactgcatac ggaggaggac gacctgcctc tgctcgtcga ctggcgcgcg aacgcggcgc
     3841 ggcctttcta cgaggcgaca ccggtccacc cgatgggcct gcggcggcgc cggcacctgc
     3901 gcctcgagga gcgcacggtc atctcggtga gcgacgaact gctggacggg accgccccga
     3961 cccacgatga catcgtgggg gacggcccgt tgaccgaggc tctgtcggca cggcgtacgg
     4021 gcaggatgca cgcggccgtc gcgacgctgc aggccgagca ggacgagatc gtccgctccg
     4081 cccaccgcgg ggtgaccgtg gtgcagggcg gccccggcac cggcaagacg gtggccgccc
     4141 tgcaccgggc ggcctatgtc ctgtacgcgt tcccacgcgc cgcggaggaa ggtgtcctgg
     4201 tggtggggcc gaacgcccgg ttcctcgact acatctgcca ggtcctcccc tcgctcggcg
     4261 agaacgacgt cgtcctggcg acctgccggg aactggccgg agcgtccacg gacacggtcg
     4321 acccgttcga tacggcgcgc ctcaagggcg gctccggcct cgccgacgcc ttggccggcc
     4381 tgctgcgcgt ccaccaagcc cccgccggtg acttcaccgt gcgggtcgga caggaactgg
     4441 ttcacctctc cggcgaggag gtcgccacgg cacgcgacgc cgccgtggca gccgttgcgg
     4501 ggcacaaccc cgcgcgccag gtgttcaaag agctcctggc cgacgccgtc accgacgcga
     4561 tgcgacgaga catgggtgac ctcctggagc agatcgacgc cgatgccgaa aggatgacgg
     4621 gcatcaacct cgaccggttc acgggagccg cccagcgccg cgtcgaaggc gcggccgatc
     4681 ccggcccggc ccacgaactg gacctggacg ccgtccgggc cgatctcctc gacgacgccg
     4741 gcgtcgaccg agcggtcgag gtgttgtggc cgcggctggc acccggtgac ctcgtgaagg
     4801 cactcctgac gaacgccgca gctctcgccg agcacctgcc ccgcctgacc gcgcacgagc
     4861 ggtcccttct gctgcgcggc ccggacgacc cgtggaccgt tgccgatgcg ccgttgctgg
     4921 acgaggcggc gagcctggtc gacggcccac ccgagcggac gtacgggcac gtcgtcgtcg
     4981 acgaggcgca ggaactgacc gccatgcagt ggcggatgat cgtccgccgc tgcccgtcga
     5041 ggtcgatgac gctggtgggt gacttcgccc aggcaggccc ggtcgcgacg gcacgcgact
     5101 ggaaggaagc actgggcccc cacgccggac cgaggttcaa actgcacaac ctgaccgtca
     5161 gctaccgcac cacgcaggag atcctggcaa gcgtccggga cctgctcacc cggatcgctc
     5221 cggaccagaa gcccacacga tcactgcgaa gcggtgagaa ccctcgcacc gtgaccacac
     5281 ctccggacgg gctggtcacc gccgtcgttc acgaactccg cgcccagagc gccgcgtacc
     5341 cgggcgagct tgcgggagtg atctgcgcgg acaccagggt gagcgaactg acggcccagg
     5401 gcatcgctca ccacgcacgc atcgtgccgg cgtccgaagc acgcggcctg gaattcgaca
     5461 cggtcgtcgt cctgaacccc gaggaaatca tcaccaaccg ccccggcggc gaaagggact
     5521 tgtacgtagc cctgacccgg gccaccaagc gcctttgcac catcaccgtc cagcccgcct
     5581 gacggcccgg cacccgcgcc gtcgctgcgc gggcgcaccc ggcgcggcgc agacaccggc
     5641 ccgcgcgcca tcgaggcccg caccgcagcc cctccaccac cgcccgcgac cagtaccccg
     5701 gcgggatgcc cggagccggg accagccccg cgagccgtgt ccaacgccag gtggcaaccg
     5761 gggccccggc cgtttgacgg cctggtgttc gccgtacccg ccgcgtggtg ccatgacggc
     5821 tctctctgtt ctctcgctgc gccctgtgcg tcaacacccg gtccgggccg gggcacccgg
     5881 atcgcctcca tgactggctc gatttgcggg ggaaccgccc cgctgcccgg ccgtgacacg
     5941 accggcaggg gcttgcggtc ctgctcgacc gcgaggtgga tctggctcgt ccgtccgccc
     6001 cgggtcggca cgggcacggg gtggacggcc cgttcggcat cgcgcccggg agaatcacgc
     6061 cgtgcgaacg gccgagtcgg ctccgcgtcc ggtccgtgaa gacggcttca gccgcggacc
     6121 gcgccggtga acgcgggcaa cgacccgccg gtgatgcccg tccgtccggt cccggcggcc
     6181 actgcggtcc ggagcgccgt cgggctcccg gccgtcccgg ccgctggccg cgacgcgcca
     6241 ggcgcgaccc atcgcaccat ccccacagcc gcacgacggg gtgccgtgtc cgggacacgg
     6301 cacaccccgc acgccgcgca aggcggtgcg gataccgcgc ctgccgatct cggcccggcc
     6361 gggccggcga atccccggcg gcgagaggct cccgtgcgct ctgcgggacg cccaggatcc
     6421 gatcagcggg gcaggtccgg gcggggcagt ccgatcgggt tgggaaaggc agtacgccgc
     6481 aggacgtgat ggcgcggacg gccggggtca gtgtgtgcag gaggcggtcc gcatccggtt
     6541 cccgcagggg gcgcaacagc cgttgggcga ggcggttggt ggcgtcctcg atgtgttcgc
     6601 gttcctggcg gcctcgtgcg gtggcgttgc cgtgttcgtc gagcagggcg cgtgaccgca
     6661 attcggttgg gcgggccggc gacaggctga ggggccggtg aggcatcgcg tccccaccgg
     6721 gtccccgggt tgccgacgtt cgacgccgcc gacctgatcg cgttcgcgac catcgagggc
     6781 gcgcgggcct gcgggatcga cgaccgcacc ggcagtgtga cgccgggcaa ggaggccgac
     6841 ctgatcatgg tccgcctcga ccacaccaac ctcctgcccg cgacggacgt ggcggcgtcc
     6901 atcgtcgcgg gcggacacgc cgggaacgcc gacctggtcg tcgtggccgg cgaggtcctc
     6961 aaggaagacg gagcactggt caggggcgac tccgtcttcg cggaggcggc ggcctcccgg
     7021 gaccggctgt tccacgcggc cggcctgccg ctcccctcct gagccggacc ccgcagcccg
     7081 tcccggccct gtcccggtcc tgtcccgtcc cggtcggtcg ggccgcgacg ggccggccaa
     7141 cgcgccgggg cggcgggagt tgatgccgtc tgcctccggc aaggcggctt cgcgggggct
     7201 ggctggcggg tcgggggggt gggcggaagg gcataggcgg ctgtccggga ggtcaacaac
     7261 tgccgtgttg gtcccgggtt ggccttgtgg tggtattcac tcgtccccac cggccgtggc
     7321 aggcacatgg tgtccgggcc gggcagggct gtccggggcc tgcggtgtgt gggacgcccc
     7381 tcgttgtggg gcggtgcggg ggccgggttc cgttgaaggt ttgcgctgta aggggaaggg
     7441 agtgggagtg gccggcgatg tgctggagaa tctcgatggt ctcctgtctc cttacggggt
     7501 ggccgggggc gtcagggagt tgccgtatgc gccgggggag cccacggtgc cggcgtacgg
     7561 ggcgctggcc ggccatgtgc tgcgtctgct ggacgcggat ccttttcacc ggccgggcgg
     7621 gccggggggc aggcccggtg cctcgtacga ctacagttcg gccgggaccg cccagagtcc
     7681 tgagcgggca cgtctgctgg ctttggcgga gcttttggag cgctactgcg ccacgatggc
     7741 ccaggaccct ggtgtcgtgg tgcgggccag cgcggtggag ctgggggacg aggcgctgga
     7801 tctggggtcg ttgccgcggc tgtcggccca ggagtacgcc tgcgcgggcc agccgctgct
     7861 gccgccggat cccgctgcgc cgatgcggtg ggtgcgcggc tggtcgctga cccggcggcg
     7921 cccggtgtac gtgccggcgg tgatcgcgtg gatggggtgt gccccgcagc ggcccgcgga
     7981 gcgtatctgg cacccggtca gtaccggttt cgcggtccac ggagatctgc gtaccgcggt
     8041 gatgcacgcg ctgtgcgagt gcgtggagcg tgacatgatc agcacggtgt ggctgcgccg
     8101 tctgccgctg ccgcggctgg acatcggccg cgtgagtgaa ctgggggatg cggcccgggt
     8161 gatgctggag cgttaccggc ggtcggtcct ggccgatccg gtcctgttcg atgccacttc
     8221 cgatctgggg attcccacga tctacctggt ggggcgtgcg ccgcacagtt cgcgtgcggc
     8281 cacgatggtg gggtgtgcgt ccggggccga tccgcagcag gtgctggcca aggtgctgcg
     8341 tgaggtgatc gcctaccggg tcgcgctcca cgtcgaccat gaggttcctg ccgaggtcgg
     8401 tgacttccag gatgtgctgg acggtgcgca gtggatgggc cggcccgagc gtgcggatgc
     8461 tttcggcttc ctgctgtccg gtgagcggcg tgcgcggctg tcggacatgc cggtgctggc
     8521 gcgtggtgat gccgccggtg atccggatct ggtggtcggg cggctgcgtg agcggggtat
     8581 ggaggcggtg gcggtggatg tcaccaccga tgaggcgcgt gatgtcggtt tccatgcggt
     8641 ccgtgtcttc gtccctcagc tcgttccgct gtcgttccag caaaacggcc gttatctcgg
     8701 tcatccccgg ctgctggacg ctcctgagcg gctgggttat cccgagtgtg ccggtacgga
     8761 catcaacccg ctgccccagc ccttcgcctg acgtccccca cccccaatcc cccttccctt
     8821 cttccttcct gcttgtttcc tcgtcccttg tcggccggtg tgccggcgct ctgccttgga
     8881 ggtccgtgtc gtgggcgtgc cgccccttca cctggtagcc ctggacgcgt ggggcgaggc
     8941 cgtggtgccg cagccggacc gcggcgtggt ggtctcggcc gtctccgcgg cgccgcgggc
     9001 cggcgccggg ggccgtacgg tgtccgcggc tccggccacg tggccgcagg cggggtgtca
     9061 cgtggtggcc tgtgcgcgtg aggacgtctc cttcttccgt gacgtcgaca cgttctgctt
     9121 cctgtggtcg ctgacctggg cgcctttggt cctcacgccc cgcggggtgc ggctggggcc
     9181 cgtggtggtg ccgggccgtt ccgcctgcta ccactgtttc ctgcggcggc agaggcagca
     9241 cgactgggat gtcggcgata cccaggcctg gtgggacagc gtcacccggg acccttcgaa
     9301 ctgcgtggcg gggtggctgc cttcggacgt tctgatggcc cggggactga cccgggtgct
     9361 ggccgccagg gggcccggcg cgttcgccgg gacggtggtg acctacgacg gggtgaccgg
     9421 ggacgtcagc ggtgacccgg tgaccggggt gcacgcctgt ccgcgctgcc ggcgccgccc
     9481 ggaccgccgc gccgatacct ggaccgccct ggcccagcag ttcccgcccc cgtccgcgac
     9541 ggcctgcccg cccgtatccg cgccggtctg cccggctggt ggggagcagg cccggtgaaa
     9601 ctcccgaccc ggtcggtggg ggccggcacc gccgcccgtc acctgcaccg cagcccgctg
     9661 cctgctgtgc cgcggctgcc ccggctgcgt cacggcatcc ggttcctgag gctgccggac
     9721 ggtatccagt tcgacggcgg gcccgaacgc gaggtcctgc ggggcaccgc gacccggcac
     9781 ctgctgccgc gcctgctccc gctgctggac ggggcccacg acgtggccgc tctggccgag
     9841 gcggccggca gcgagaccgg cgtgatcgaa cgcctgctgg ccctgctgca ccttcgcggg
     9901 ctgctggaag agggcgcctt cgtccccggc acgcccacgg cgctggcgct gtccaggctg
     9961 ggcgccacca cctgggccga tgcccacgcc gggcagagtg tggaccggct ggcggccgcc
    10021 cgggtggccc tgcacggcac cgcgcccctg ctgtccgaac tggccggagc cctgcgcgaa
    10081 gccgggacgg gggaggtggt gaccgccggg ccgcaaccgt gcccggccga cctggcggtg
    10141 gtcctcctcg gaccctgcgg catggccggt gacgaggctg agcggctgtc cgcggcgtac
    10201 gcacgggaac cggtggcgct cctgccctgg ttcgtggccg ggcccgtctc ggtgatcggc
    10261 ccgctgctcg cccccgaact cgacctgtgc ctgggctgtc tgcggcggga gctggccgac
    10321 accggcagca ccccgccgcc cggccccgcc gacccctgga cggcggtcca cgccgcgctg
    10381 gcctgccgcg aggtcctggc cttgctcgcc cacgtcccgc ccgcccactc cccggacggc
    10441 gccacccgct acgacctgga ggcatggacg accgaacgcg ccatgcccac cgccggcccg
    10501 tcctgccccg tctgccgccc gcggtcggcc gccgaggagg cgtccgagcc cgccgcgtgt
    10561 cccggctgca ccccggcagc cggccgtctc cccggcgccg acgttccgtc agaccacctg
    10621 cccactgccg gctcgtcctg ccccgcctgc cacccgcggt cggccgccga ggaggcgtgc
    10681 gagcccgccc cgcgtcctgc ctgcgttccg gcagcccacc gtccccccga tgccgacgtt
    10741 ccggcggccc acgtgcccac tgccggctcg tcctgccccg cctgccaccc gcggtcggcc
    10801 gccgaggagg cgtgcgagcc cgccgcgtgt cccggctgcg tcccggcagc cggccgtccg
    10861 ctcgacgccg acccggtgtc cgtcgcggtc cgctaccacc aggcggtcgc caagccggca
    10921 ctgcaccggg tgacccccgc ctcccgcctg cagtctttga gccgcctgcc ggcagcggta
    10981 caggaacgcc gccggtggcc cagcgccgct ctggtccccc tgccggctct gcccgccccc
    11041 ggcaccccgt ggcgccccgc cgggcccccc ggcacctcgt ggggcggcgc cgcggacgcc
    11101 ggcacaccac ggggccccgc cgggcccccc ggcatcccgt gggacggcgc cggcgccggt
    11161 gcggcgaccg cggccaaggc accggctctg ggcgacctcg cgctgctgct cggcatgacc
    11221 gcgggccgcc gcggcgcgca gggcatggat ttctgggcac ccagcggcgg caacctcggc
    11281 tcaccgtgcc tgtacctggc cgcgcggggc atcgacgggc tcgccgacgg ctgctacggc
    11341 tacgacgccc tcgcccacgc gctggcccgg ctcgccggcc tgcccgccgt ggacctcgtt
    11401 cccggcccgc acgcccctag cgccgtgctg gtgctgaccg gcgacgtgcc gcggatccag
    11461 ggcaagtacg gccccttcgc cctgcacctg gcctgcctgg acgccggggt cgccctcacc
    11521 cagctcgaga ccgccgccgg cctgctcgga caccgtgtca ccctccacga cgacctgccc
    11581 gcgccgggcg tcgcggccct ggccgacgcc tttttgatcg actccggccg ggaaccggtc
    11641 accgcggtcc tgtcggtgac accgcatgcc cgcgaccgcg gtgagccccc gccgtccacg
    11701 ggcgccgccg gccccgtcca cccccaggag cggtgatggc ggacaccttc ccgctcccgg
    11761 cgaccccgca gcaactggcc gacggcctcc tgcgcgccta cgcggccgga cagccgggcg
    11821 caggcggcac cgtcccgccc cggctgcgcc ccggcctgcc cgccggcacc gcgccgcgcc
    11881 accggctgcc gcccccggcc ccgccgctgc ggtccttgca cgccgtgctg gacgagcgcc
    11941 gcacggtgcg tgacttcgcc gccacgcccc tgccggacgc cgtcctggcc gcggtgctgg
    12001 ccgcggcgcg cgaacacgac gcccgcaccg cacccggcga gacccgggcg ggcaacggcc
    12061 tggccccgct cgtcgtcgca cggcgcgttg ccggactcac cccggccgtc tacggcacgg
    12121 ggcccgaccc ggcctgcctg taccggtacg ggccgctcac gtccccggca tggcactgcc
    12181 tgttcgccga tccgcagatc gccggcgcac ccgtgctggt cgtgatggcc ggcagcgtcg
    12241 cagccgcctg catccggcac ggcgcacgcg gccacctgcg gctgctgcgc cgggccggat
    12301 cggccgtgca cgccggctgg ctggccgcac tccagcgcgg atacggcggg gtgatcctgg
    12361 gcgccacact gcccagcccc gaactgtccg cgaccgcccg cctggacccg gtcagccgcc
    12421 ggcccctggc cgccctggcc ctgggcaccc ccggaccgga cccgttaccg caccccgcgg
    12481 ccccgtcttc cgccgggcgc tgaccggcgg accaccgacg tgcaccgcca accggcggcg
    12541 cagcaacccc agacacgcat aaggaggtga ttcggtcatg atcgaaaagg agaacgagaa
    12601 cgccgccgag gcggacgagt tcctgtacgc ggaggtcctc gaggacaccg cgacgtccta
    12661 cagcaagggc agctccagct gcggcttcaa cccttcgggt acctgatgca gtggccggcg
    12721 ggagcgcagc gctcccgccg gccgccgcac accgcgccgt ggggccaccg gccctgcggc
    12781 ccgggcaggc ggtgcgggcg gatcgaggaa agaaagagag tgttccatgc ggcttcccgg
    12841 cgcgttcacc gcgattccga cggtgaccgg ggacggcgtc cggctgcgcg caccgcgcca
    12901 ggaagacctg cccggcctgg tccgcgcgtt cagcgacgag cgggtccgcc gcttcatgcc
    12961 ggtaccgtgc gaatacaccg ccgcccacgc ccagaacttc atcgacaccg cgccggcgat
    13021 gtggcgggcg caccgcgcgg tcttcgtgct ggcggacgcg gccagcgaca ccttcatcgg
    13081 cgaggcggaa ctgctctcgc tcaacgagct ctaccgcagc gccgaggccg cgttcctgct
    13141 cgacgcgccc gcccggcgcc tgcgcacagc ggtggccggc gtgcgcctgc tgtgccggtt
    13201 cggcttcgag gaactggggc tgacccgcat cgaggccttc accgacctgg acaacagggc
    13261 cgtccactac gtgggagcgc acgcgggctt ccgcaaggag gggatcgcca ggggaaagat
    13321 ccccggcccc ggcggacagc gccgggactg cctggtggcg gcactgctgc ccggggacct
    13381 ggcaccacaa cggtaaggca gccggtcggc tgcggcacac agggcagatg cgggtacgcg
    13441 gtgtccgcgg aaaggggggg cggtacccat ggccggccct gccatcgagg cggtccgact
    13501 cacccgcacc ttcggcgggt ccaccgctgt cgacgccttc gacctgacgg tcgcggccgg
    13561 cacggtggtg tccctgctcg gccccaacgg ggccggcaag accacgatcg tgcgcatgct
    13621 cgccaccctc atccggccca cctccggctc ggcgcgggtg tgcggtcacg acatcaccac
    13681 ccgcccgcag gcggtgcgct ccgtgatcag cctgacggga cagttcaccg cgctggaaga
    13741 caccctgacc gcgcgcgaga acctgctgct gatggcacgg ctgcgcggac acggcaaacg
    13801 cggggcggcc aaggtcaccg actggctggt ggaccgcttc gaactcgggg cgttccgcga
    13861 ccagctcgtc aagacgctct ccggcggcca gcgccgccgc gtcgacctcg cggccggcct
    13921 cgtcgtccag ccccgcctgc tggtgctcga cgagccgacc accggcctgg acccccgcag
    13981 ccgcgagacc gtctggtcca ccgtccgcga gctggtggcc gaaggcgtca ccctcctgct
    14041 gaccacgcag tacctggacg aggcggacgc cctgtcggac cacatcgtcc tgctcgaaca
    14101 cggccgggcg acggcaagcg gaaccccggc ccagctcaaa agacgcgtcg gacaccagcg
    14161 catcgatgtc accacggcgg acgccaccgg gttcacccgg ctgcgggcgg ccctggcacc
    14221 ccggttcacc ctcaccggcg tccccgagcg gctcctgctg caactccccg ccccgcacgc
    14281 ggcacaggac ctggccgccg tcagccaggc cgtgcgcgac agcggcgtgc ccgtcgagga
    14341 gatcgtcctg cgaagcccga ccctggacga cgtcttcctg accctgaccg gtcacccccc
    14401 caaggacagg acatgaccac ccccaccccg ccgcgccccg ctccgccccg gccggccacg
    14461 caccagcgca aggccctgcg ccgcttccgc acctggcgct acctgcgcga gaccgctctg
    14521 ctggtctccc gtacgctgcg cgtcgcggcg cggatgcccg tccgcatcgg cggcgtgacg
    14581 ctgcagccgg tggtcaacac cgtcttgttc gtcaccgtct tcggcagcgc cgtccacatc
    14641 cccgcaacac gctacccgga ctacctgctg cccggcctga tcgcccagtc cgtcgccttc
    14701 ggcggggtca gcgcgggggt cgccaccgcc acggacttct ccctcggcgt catcgaccgt
    14761 ctcacctccc tgccgatcac ccgcctggcc gtcatcaccg cgcagatcgt gggccaggtc
    14821 atcgaacagg ccgccagcat gctcgtcgtc gcctgcctgg gcgccgcact cggctggcgc
    14881 ccccgcgtga acgccgacgc catctgcgaa ctggccgggc tgctgctgct cgggctgttc
    14941 gccttcacca ccttcggcgt gctcctgggc acgatcgtgc gcacccccgc caccatccag
    15001 ggcctcggct acggcatcct cctgccgctg gtgttcctcg gcggcaccta cgtccccgtc
    15061 accggcatgc agaccctccc gcggacgatc gccgagtaca acccgatcgc cgccctcgtc
    15121 gccgccgtcc gccaggtggc ccagggcacc ggctccaccg gcagcttgat gctggaacac
    15181 ccggtcccct ccaccgccgc ctgctgcacc ctcctcatcg ccgtctgcct gcccctggcc
    15241 gtgaagaagt tcggccccgg gccctgagcc cgccccccac gacgtgtgca cggccgacgg
    15301 gaaccggcgt ggagccagga gccccgccgg cccccggctt cccgcccggc ggcgccggcc
    15361 ccaccgccaa cgccaggaca gaccaccact ggcccgcaga ctcgggccgg cccggctgag
    15421 ctgccccgac tttcgtagag tccgcgatcg tgtgatcaag cggtctgtgg gacttgctcc
    15481 ggtctcgccc agtacgcctg ttcgtactcg tcgggtggca ggtagccgag ggcggagtgg
    15541 agtcgttcac cgttgtacca cgcgacccac tggaagacgg cccgctcgac ttcgtcgaag
    15601 tcccgccacg ggccctgatg ctcgatcagt tcggccttga atgtgccatt caaggcctcg
    15661 gccatcgcgt tgtcgtacga atcggcgacg gagcccacgg acgcggaggc gccggcctcg
    15721 gccaatcgct ccgtatagcg aatggacacg tattgcgacc cgcggtcgct gtgatgaatg
    15781 aggccggcgt ccttcttgat ctgctgccgc cacagcgcca tctccagtgc gtccagcggc
    15841 aggtccgtgc gcatgtgggt ggcggcctgc cagcccacga tccggcggga gtacgcgtcc
    15901 aggacgaacg ccacgtagac ccagcccgac cacgtgcgga tgtaggtcag gtccgccaac
    15961 cacagctggt tcggccgctc ggcggtgaac cgccggttga ccagatccgg cggacgcggc
    16021 gcggtcggct cggggaccgt ggtgcgacga cgttgcccgc ggatgacgcc ctcgatcccg
    16081 agctcccgca tcagccgctc gaccgtgcag cgggccaccg cgtggccggc gcggaccagc
    16141 gcgcgggtga cccggcgggc gccgtaggtg cggccggagt cctcccacgc ggctgtgacc
    16201 agcggaatca gctcttcatc acgcaaccgg cgggcggact tcggtcgcgt cttgcgcgcg
    16261 aagtacgtcg agggagacaa gcccagcacc cggcagacgg gatcgacccc gaggcccttg
    16321 tctcgcaggt ggtcgatcac ctgctcggcc tcgtccgggg acggtcgatc tcctgggcaa
    16381 aaaacacgct ggcggccttg agaatctcgt tggcccgcct caactcggca ttctctttcc
    16441 ggagttgctt cagctcctcc agctcggagc tggtcaggcg gtcgtcgcgc tcgccggcgt
    16501 cggcctcggc ctggcgaacc catgaccgca gggcctcctt gtggatgccg aggtcgcggg
    16561 cgacatgcgt cactgggcgg ccggtcgagc ggacctcgcg gacggcgcgc tcgcggagtt
    16621 catcggggta cttacgtggt gctggcac
//
