LOCUS       reptomyces_RBGC_594038 16483 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_594038
VERSION     Streptomyces_RBGC_594038
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000154965.1
  ORGANISM  GCF_000154965.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..735)
                     /protein_domains="PF01292"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159908"
                     /pseudo=False
                     /translation="MRSTAGSTKPTGTATRPEREGRVRRFSTAERLVHRATGYLMLLCL
                     VSAACLYLGPLAQLVGRRHLMVTVHEWSGISLPLPVLLGLLSPAFRADLRRLNRFAVYD
                     RQWLRAVRRRRTSPEARPAGKFNAGQKLYAGWIAGAVLVMMFTGLLMWFMGLLPFISRT
                     SAIFVHDILAWAITFVLLGHMRRAFEDPEARSGMRTGYVSLSWAQRYHSRWLPEERVGD
                     GAEDAKVRRMTPRAPGRPGRQS*"
     CDS             complement(684..1096)
                     /protein_domains="PF00174"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159909"
                     /pseudo=False
                     /translation="MPQTRVVHDVVCTDGWRVAKTPWEGVRLADILDDAGVRSPSAAIR
                     FTCFDGAYTESLTLEQARRSDVLVALNMQDKPITHAHGGPVRLYVAPMYFYKSAKWLSG
                     VSVTDKVVPGYWEERGYAVDGWLDEADRNSDAA*"
     CDS             1836..3469
                     /protein_domains="PF00005"
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159910"
                     /pseudo=False
                     /translation="MSDAAIVCSNLSFAWPDDTPVFQDLSFTVPTGRTGLVAPNGSGKS
                     TLLKLIAGELEPATGSVSVSGTLGHLPQSLPLTGDLTVAEVLGVATVIRALDAVESGDV
                     DEKHFATIGDDWDIEERTRAQLDRLGLAGLTLDRSLSTLSGGQVVSLGLAAQLLKRPDV
                     LLLDEPTNNLDVEARHKLYDVLSDFTGCLLLVSHDRALLDRMERIAELGSDELRLYGGN
                     FTAYEEAVRAEQEVAEKNVRNAEQELKREKREMQQARERAERRMSNASKNLKHAGLPKI
                     FAGNMKRGAQEAAGRSGTMHASRVGEAKARLDEAGRALRDEQRLTLELPDTQVPAGRNL
                     FLGKDMQVRLGNRNVFAEGGVDLTVRGPEHIALTGPNGAGKTTLMRLITGELAPDSGEI
                     KRNDGRVAYLSQRLDLLKSDHTVAENFAAFAPERPEAERMNLLARFLFRGARAHLPVGV
                     LSGGERLRATLACVLCAEPAPHLLLLDEPTNNLDLVSAGQLESALNSYQGAFMVVSHDE
                     RFLAAIGVNRWLRLADGALKETGAPEV*"
     CDS             3551..5937
                     /protein_domains="PF00005"
                     /protein_domains="PF07336"
                     /protein_domains="PF11706"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159911"
                     /pseudo=False
                     /translation="VPQSPLPQPALLALDLVRTLGGRRVLDGISLTASPGHRIGLIGEN
                     GVGKSTLLRVLAGTDEPDAGSVTRPADLGFLHQEMPYDACSTIAVVLDEALREAREDLA
                     ELDRLGAELALLPEDDPGHQDLLDAYGRRLEQAQDRESWDADRRAALVLDGLGLGAFGH
                     ERTLGSLSGGQRGRLALAALLVRRPSALLLDEPTNHLDDGAAAFLEEQIRALPGTVVLA
                     SHDRAFLDAVCTDVIDLDPAVDGPVRYGGNYSAYLSYKRAERERWERRYAEEQEELAEL
                     RKAVGVTAHRVAPDRGRTDNEKMGYGHRAGRVQNQISRRVRNATRRLEDLERAQVAEPP
                     RPLRFAAGDMAAHREEDSGPLLSLHGIRVPGRLTLGCLEISPTDRLXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFVCGHPALDFAATLRARRSAR
                     FEMFVTPERLNAWYLESGLVDTVTPGGEDDVREATTVREAVYRLVTDRRLGDEFNREAL
                     GVLNAAARKTPATPQLTLSGRHTDATPEQALATVARQAVELLSGPDVPLMKECGNPECT
                     RVYIDRSRGMRRQWCGMESCGNKIKAAAYRARKKSAPAAAAR*"
     CDS             6254..6816
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159912"
                     /pseudo=False
                     /translation="VTSQSAATLRSRYVAQAASDLEENRRRQQELAERINVLKQEEALL
                     SDILNLAERYASFADASRVPEQSQDEPPVAKAKRAPAGTTARRSASAKSAPATKTAKDG
                     AKAKSHQPLLGDLLAELLGQYKEPRPAKELRDELLAKHPDRSPTPQVVRNTLESLVAKG
                     RIRRHKQQRSVMYTLVKQGGTDTD*"
     CDS             complement(7003..7442)
                     /protein_domains="PF00903"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159913"
                     /pseudo=False
                     /translation="MKLEVVILPVSDVERAKGFYVEQLGWRLDADFPINDGYRIVQVTP
                     PGSACSVIFGKGLTEQEAGTLHGLQLTVTDILKAKEELTSSGVEVVGPFRDETGAFHHA
                     GDTHRVPGVHPERASYGTFAAFKDLDGNEWFLQEITERAPGR*"
     CDS             complement(7540..7736)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159914"
                     /pseudo=False
                     /translation="MAATTHTYVRIAPRPRSDGAGVTGERPSRNAVRPQDRDWPTDTRV
                     WNWTESAALWGYGPSPSAFL*"
     CDS             complement(7798..8147)
                     /protein_domains="PF02566"
                     /protein_domains="TIGR03561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159915"
                     /pseudo=False
                     /translation="MAVSYTAVVDVDGEGRNGGQVRSSVAAGWAACFLGALRRAATTRR
                     IRLTSTAITAEITLTHGDDGGFSLSAVLNPVLGGVDQATAQELAEAAHQICPYSKATRD
                     NIPVTVNAGVAA*"
     CDS             complement(8225..8421)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159916"
                     /pseudo=False
                     /translation="MNKGLTTEAAEAAVRHARFGKLPERIRFDDMTEAVEADPAGRANG
                     SYDPEGSWKFYSCLALDLGL*"
     CDS             complement(8611..8753)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MTPTRLWSSVPSTSQWGANLTRAVLPGGSFGTTGRTYATWGSGRW
                     GS"
     CDS             complement(8780..10221)
                     /protein_domains="PF00171"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159917"
                     /pseudo=False
                     /translation="MITYDRLFVGGSWVEPSDPEPLDIPSPHDRSVIGRAVQARPADVD
                     QAVAAARASFEEGVWRLTPPAERIAALRRFNALREENAERVARLISLENGSAGWFTRAG
                     QPGLTRQANAYLRAAEEFAWEETLAPSDPQSPVRSVVRREAVGVVAAVIPWNSPFSSAT
                     SKIIPALLAGNSVILKVSPENSLSMGFLAELLERVGLPEGVISVLPADRETSEYLVSHG
                     DVDKIAFTGSTRAGRRIAAIAGEQLKRVSLELGGKSAAVILPDADIDRAVAGLKFGSLL
                     NNGESCIAQTRILAPRSRYEEVVAALKELVESLKVGDPNEPDTFIGPMIRPDQQERVRG
                     YIQLGIEEGARLVTGGPQVPEDLEKGNYVTPTVFADVDNSMRIAQEEIFGPVLVVIAYD
                     DEDDAVRIANDSEYGLSGGVWSADEEHALAVARRIRTGTVTVNGASVAFDGPFGGFKAS
                     GIGREYGAVGLGTYTEYKTITV*"
     CDS             10515..11590
                     /protein_domains="PF00561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159918"
                     /pseudo=False
                     /translation="MINRRTFSKAVGLGTGAAAVSLAGLQTNAAATTATTALDEPGGGP
                     TPAVPSITPGTHTEFGTLKHVKAGVLDIGYAEVGPQHGPVVVLLHGWPYDIHSFVDVAP
                     LLADLGYRVLVPYLRGHGSTRFLSRHTPRTAEQSAIALDIIAFMDALKIEKAVLAGFDW
                     GSRTADIIAALWPERVKSLVSTSGYLITDRKMQLEPAAAGVEHNWWYQWYFATDRGVKA
                     MENVDERIALCRYVWTLVSPNWNFSDATFARTADAFRNPDYAAIVLYNYRWRISLIDGD
                     RRYDRYEKQLAAQPSIGVPTVTLDAALDPFTAPGDGSGYRSHFTGPYLHRTIANIGHNL
                     PQEAPTVFAQAVVDADRL*"
     CDS             11874..12733
                     /protein_domains="PF12697"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159919"
                     /pseudo=False
                     /translation="VVSIKGGRKRLLTGAVATAAAGLALGAFALSGTANGATETADAAG
                     AAKHAKPTIILEHGAFADGSSWNGVIADLRADGYPVVAAANPLRGPASDAAALRTVLDH
                     VKGPKIVVGHSYGGNVISAAATAAPEVKALVYVAAFLPAPGESALELTNKYPGSTLPAA
                     LDPVTYQQADGSTATDLYIQQDKFHHQFAADVPAGQAALMAAEQRPIAQAALEEKATTA
                     AWKTKPSWDIITTEDLNIPPAVQRFMAKRAHAHTTEVAASHSVAVSHPHLVAAVIERAA
                     RATVR*"
     CDS             complement(12953..13752)
                     /protein_domains="PF13673"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159920"
                     /pseudo=False
                     /translation="VSNLTAAIESVSQLTTGWRAMVLDRDEQADVRDLPGLAVRWADCR
                     FAFWNAVTLTETGTDATLLEKRLRQAADIMGSKRQPGFLWLFEDLLADDARAALEEAAE
                     RAGLAYAFPGTGMAGDLLPIPEPHHPDLTFERVTTDEHLLAYADLNSRAYGFPLEDGRD
                     GLAGSALWKQEVYAYLALRDGTPVACAATVEAQGRLFVVLVATDPGWQRRGYGEAVTRK
                     ALYEGARATGLTRATLHATAAGAPVYPRIGFEPNSPMRFYALKG*"
     CDS             complement(14333..15798)
                     /protein_domains="PF07690"
                     /protein_domains="PF07690"
                     /protein_domains="TIGR00711"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159921"
                     /pseudo=False
                     /translation="MTKADNSSSPRAGGVAAAMSALVLAVLLAALDQTIVSTALPRIAE
                     DLNGFDDIAWVSAAYLLASTAVTPLWGKLGDMFGRRPLYLASTSVFLIASVACGLAQNL
                     AELVGARVLQGVGGGGMIVLTFALVGDIVAPSERGRYQGMFGSVYGVASIVGPLLGGVF
                     TDQLSWRWAFLINLPVGIVALAIAARALPAATRGTRARVDYLGATVLAALATGLVLVTS
                     FGERWGWGSPAIVGLIAATIVLAVLLVPVERHAAAPVLPPAMFASRTVVFSSLIAFFAN
                     AAMFSVLVYLPTYLQIVHGVSATLSGVHMLPLVAGLVVSQSLAGRWAAQVGRLRTILLA
                     GLVANLAGLLLLGTIGAATNALVLSVYFLITGVGIGMVPMVVLTTVQNSVPAADLGAAS
                     AVVTFARSIGAAFGVAVFGTLLNTGFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXPVPEAGTQDRRDRRP*"
     CDS             15903..16483
                     /protein_domains="PF00440"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3159922"
                     /pseudo=False
                     /translation="MSQASHLATRISAVRADAARNLEAVLTTGARMLAADPGASIASIA
                     AEAGVDRRTVYRRFASREDLLAAIYEARLTAIEHAIEDARLREAPVAVALHRYVENIIT
                     VNRTWPVDLARMLTDHSVHARRDAAVEEVDTFLRRATDEGLLRSGLPQGWASVLLPQLM
                     HLVSRQLPELSAGQGADVVVDTLLNGLGTS*"
ORIGIN
        1 ctatgactgt cggccgggcc tgccgggggc acgtggggtc attcgacgga ccttcgcatc
       61 ctcggcaccg tcgcccaccc gttcctcagg caaccaccgc gagtggtacc gctgcgccca
      121 cgagaggctg acgtacccgg tacgcatccc cgaccgcgcc tcggggtcct cgaacgccct
      181 gcgcatgtgc cccaggagga cgaaggtgat cgcccaggcc agaatgtcgt gcacgaaaat
      241 cgcgctggtg cgggagatga agggcagcag ccccatgaac cacatcagca ggccggtgaa
      301 catcatcacc agcacggcac cggcgatcca gcccgcgtag agcttctgac ccgcgttgaa
      361 cttgccggcc gggcgcgctt cgggcgaggt acggcgcctg cggacggcac gcagccactg
      421 ccggtcgtac accgcgaacc ggttcagcct gcgcaggtcc gcacggaagg cgggtgagag
      481 gagccccagc aggacgggca gcggcagcga gatgccggac cattcgtgga ccgtgaccat
      541 caggtggcgc cggccgacga gttgggccag tggcccgaga tagagacagg cggcggagac
      601 caggcacagc agcatcagat atccggtggc ccggtggacc aagcgctcag cggtgctgaa
      661 acgacgtacc cggccctcgc gttcaggccg cgtcgctgtt ccggtcggct tcgtcgagcc
      721 agccgtcgac cgcataaccg cgctcctccc agtagccggg aacgaccttg tcggtgacgg
      781 agacaccgga cagccacttg gccgacttgt agaagtacat gggggccacg tacaggcgga
      841 ccgggccgcc gtgcgcgtgg gtgatgggtt tgtcctgcat gttcagtgcc accaggacgt
      901 ccgagcggcg ggcctgttcg agggtgaggc tctcggtgta ggcgccgtcg aagcaggtga
      961 accggattgc agcgctcggc gaacgcaccc cggcgtcgtc gaggatgtcc gccagcctca
     1021 ccccctccca gggggtcttg gccacgcgcc agccgtcagt gcacacgaca tcgtggacga
     1081 cccgggtctg gggcatcgca cgcagctggg tcgagcgtgt acgtcttcgg ccggtcgacc
     1141 agtccgtcga cccgcaacat gtagtcggtc tcgcccttgt gcgggaccga accgacgacg
     1201 ctnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ntggtgtgcg
     1441 ccccttccgg cacatgtgac ctttgcctgg ccacgcaact gacttttgcc cggccatgcc
     1501 acatcgtcac cggtttaact ggtgacgatg ctgccatgct gccacggggc tgtcaacgca
     1561 ggccgtgccg tccatgcaca cgtatgagct cggccgacgg caacaccgcc tgcgaacgag
     1621 acggcggatg ttagactccc ggggacgttg accgtcgatc gaggagtcac agacgtggtg
     1681 ggtgaagacg acatctccgg gtgagatccg gatctgacgg ccaccggcgg gcgctgagga
     1741 gcgctgccga ggtggtccgt ttcgtcgtac ccctttcccc gtctgcccag ggcaggtaaa
     1801 cagctctgcc ctcagtcctt tcgaggtcac ctccatgtcc gacgccgcga tcgtctgctc
     1861 gaatctctcc ttcgcctggc ccgacgacac cccggtcttc caggacctgt ccttcaccgt
     1921 gcccaccggc cgcaccggcc tggtcgcccc caacggctcc ggcaagagca ccctgctcaa
     1981 gctgatcgcc ggtgaactgg agcccgccac cggctcggtg tccgtgagcg gcacccttgg
     2041 ccacctcccg cagagcctgc ccctgaccgg tgacctcacc gtcgccgagg tgctcggcgt
     2101 ggccacggtg atccgcgccc tggacgccgt ggagtccggc gacgtcgacg agaagcactt
     2161 cgccaccatc ggcgacgact gggacatcga ggaacgcacc cgcgcccagc tcgaccgcct
     2221 gggcctggcc ggcctcaccc tggaccgcag cctgagcacg ctcagcggtg gccaggtcgt
     2281 ctccctcggc ctcgccgccc aactgctcaa gcgccccgac gtcctgctgc tcgacgagcc
     2341 caccaacaac ctcgacgtcg aggcccggca caagctctac gacgtcctct ccgacttcac
     2401 cggctgcctg ctgctggtca gtcacgaccg cgcgctgctc gaccgcatgg aacgcatcgc
     2461 cgagctcggc agcgacgaac tgcgcctgta cggcggcaac ttcaccgcct acgaggaggc
     2521 cgtgcgcgcc gagcaggagg tcgccgagaa gaacgtccgc aacgccgaac aggaactgaa
     2581 gcgcgagaaa cgggagatgc agcaggcccg cgaacgcgcc gagcgccgga tgagcaacgc
     2641 ctccaagaac ctgaagcacg ccgggctgcc caagatcttc gccggcaaca tgaagcgcgg
     2701 cgcgcaggag gcggcgggca ggtccggcac gatgcacgcc tcccgcgtcg gcgaggccaa
     2761 ggcccgcctc gacgaggccg gacgcgccct gcgcgacgag cagcggctca ccctggaact
     2821 gcccgacacc caggtgcccg caggccgcaa tctcttcctc ggcaaggaca tgcaggtccg
     2881 cctcgggaac cggaacgtgt tcgccgaagg cggcgtcgac ctgaccgtcc gcggccccga
     2941 acacatcgcc ctgaccggcc ccaacggcgc cggaaagacc accctcatgc gcctgatcac
     3001 cggcgaactc gccccggaca gcggggagat caaacgcaac gacggccgcg tcgcctacct
     3061 ctcccagcgc ctggacctgc tgaagtcgga ccacacggtc gccgagaact tcgccgcctt
     3121 cgcccccgag cggcccgagg cggagcgcat gaacctgctc gcgcgcttcc tcttccgagg
     3181 cgcgcgggcc caccttccgg tcggggtgct ctccggcggc gaacggctgc gcgccaccct
     3241 ggcctgcgta ctgtgcgccg aaccggctcc gcacctgctg ctgctcgacg agccgaccaa
     3301 caacctcgac ctggtcagcg ccggccaact ggagagcgcg ctcaactcct accagggcgc
     3361 cttcatggtg gtcagtcacg acgagcggtt cctcgccgcg atcggcgtga accgctggct
     3421 gcggctggcc gacggggcac tcaaggagac gggagctccc gaggtgtgat ccaccgacgt
     3481 gtgacgtggc ccgcgtccga ggcgacatgc cccgcgggcc gaacaccgat cacattggac
     3541 ggtccccctg tgcctcagtc ccccctgccc cagcccgccc tgctcgccct cgacctcgtc
     3601 cgcaccctgg gcggacgacg cgttctcgac ggcatctccc tgaccgcctc gcccggccac
     3661 cgcatcggcc tgatcgggga gaacggcgtc ggcaagtcca ccctgctgcg cgtcctcgcc
     3721 ggcacggacg agcccgacgc gggcagcgtc acccgccccg ccgacctggg gttccttcac
     3781 caggagatgc cctacgacgc ctgctccacc atcgccgtag tgctggacga ggcgctgcgc
     3841 gaggcccgcg aggacctcgc cgagctggac cggctcggcg cggaactcgc tttgctcccg
     3901 gaggacgatc ccggccacca ggacctcctc gacgcctacg gcaggcgtct ggagcaggct
     3961 caggaccgcg agtcctggga cgccgaccgt cgcgcggccc tggtcctgga cggtctcggc
     4021 ctcggcgcgt tcgggcacga acggaccctc ggttccctct ccggcggtca gcgcggccgt
     4081 ctcgccctgg ccgccctgct cgtacgccgt ccgtcggcgc tgctgttgga cgagccgacc
     4141 aatcacctcg acgacggcgc ggccgccttc ctggaggagc agatccgcgc cctgcccgga
     4201 accgtggtcc tcgccagcca cgaccgggcg ttcctcgacg ccgtctgcac cgacgtgatc
     4261 gacctcgacc cggcggtcga cgggccggtc cgctacggcg gcaactacag cgcctacctg
     4321 tcgtacaagc gcgccgagcg ggagcgctgg gagcggcgtt acgccgagga gcaggaggaa
     4381 ctggcggagc tgcgaaaggc agtgggagtg accgcgcacc gggtcgcgcc ggaccggggc
     4441 cgcaccgaca acgagaagat gggctacggc caccgggccg ggcgggtgca gaatcagatc
     4501 tcccgccggg tccgcaatgc cacccggcga ctggaggacc tggagcgcgc ccaggtcgcg
     4561 gagccaccgc ggccgctgcg gttcgcagcc ggggacatgg ccgcgcaccg cgaggaggac
     4621 tccggtcccc tgctctcgct gcacggcatc cgggtgccgg gccggctcac actgggctgc
     4681 ctggagatct caccaaccga ccggctgcnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nttcgtatgc
     5401 gggcacccgg ctctcgactt cgcggccacg ctccgggccc gacgctcggc ccggttcgag
     5461 atgttcgtga cgccggagcg gctgaacgcc tggtacctgg agtccgggct ggtggacacg
     5521 gtcactcccg gcggggagga cgacgtccgc gaggccacga ccgtgcgtga ggccgtctac
     5581 cggctcgtca ccgaccgcag gctcggcgat gagttcaacc gggaggcgct cggcgtcctc
     5641 aacgccgccg cacgcaagac gcctgcgacg ccccagctca ccctgtcggg ccggcacacc
     5701 gacgcgacac cggagcaggc cctggccacc gtcgcccggc aggccgtcga gctgctcagc
     5761 ggccccgacg tgccactgat gaaggaatgc ggcaaccccg agtgcacccg ggtctacatc
     5821 gaccgttccc ggggcatgcg gcgccagtgg tgcggcatgg agtcctgcgg caacaagatc
     5881 aaggccgccg cgtaccgggc ccgcaagaag tcggcacccg cggccgccgc ccgctgaccc
     5941 ctcacccgag cgcccgcggt cctggcgaac gcggggctcc gcgcgcggcc acggtcttca
     6001 gggtcccgcg caacctgttc agcggcagcc gtcgagatca gcacaccgac ggctgggcct
     6061 cggttcacga cgcggcaaca cacctcaggt ggcgcagtgg ggggcccagc gcgcatacat
     6121 gcttctagga cacacttacc ggacagtacc tacgaagggc gcgagccatc tggcgctggc
     6181 actcgtccac acgcggccct cgggcgtggg taccatgcgc acatgtcagt catacccagg
     6241 gagtgaacgg ttgtgaccag ccaatcagcc gccacgctcc ggtcgcggta cgtagcgcaa
     6301 gccgcatcgg acctggagga gaaccgtcgg cggcaacagg agctggcgga gaggatcaac
     6361 gtcctgaagc aggaggaagc ccttctctcg gacatcctca acctcgccga gcggtacgcg
     6421 agtttcgcgg acgcgtcccg tgtgccggag cagtcgcagg acgagccgcc cgtcgcaaag
     6481 gcgaagcggg ctcccgccgg taccaccgca cggcgctcgg cgtcggccaa gtccgccccg
     6541 gccaccaaga cggcgaagga cggagcgaag gccaagtcgc accagccgct gctcggtgat
     6601 ctgttggcgg agctgctcgg ccagtacaag gagccacgtc ccgcgaagga gctgcgggac
     6661 gaactcctgg ccaagcaccc ggaccgcagt cccaccccgc aggtggtgcg caacaccctt
     6721 gagtccctgg tcgccaaggg ccgtatccgc cgccacaagc aacagcgttc cgtcatgtac
     6781 accctggtca agcagggcgg gacggacacc gactgacacc ggcaaggtgt gaaccttgcc
     6841 cacagggcgc gaacccccgt cggtgcgccc cttccggtga gtccgccggg acggggtggg
     6901 cgctccagct cgacgcgtcg tcgttccagt cggcggacat gcgattggtg cgcgatgact
     6961 gcctcgccgt tcagcggccg gtggggtgcg ggcggacggg ctcagcggcc cggggcgcgc
     7021 tcggtgatct cctgaaggaa ccactcgttg ccgtcgaggt ccttgaaagc ggcgaaggtg
     7081 ccgtagctgg ctcgctcggg gtgcacgccg ggcacccgat gggtgtcacc ggcgtggtgg
     7141 aaggcgccgg tctcgtcgcg gaaggggccg acgacctcca caccgctgga ggtcaactcc
     7201 tccttggcct tgaggatgtc ggtgacggtc agctgaaggc catggagcgt gccggcctcc
     7261 tgctcggtga ggcccttgcc gaagatcacc gagcatgcgg acccgggcgg ggtgacctga
     7321 acgatccggt agccgtcgtt gatcgggaag tcggcgtcca ggcgccaccc gagctgctcc
     7381 acgtagaagc ccttggcccg ctccacgtcg gagacgggca ggatgacgac ttcgagcttc
     7441 atgtccacgg ctgtgctctc gctttcgggt ggtgtgtttg tccgggaccc ggttctgcgt
     7501 cgggtactca gttgccgacc aggcggtcat ggcgccggtc agaggaaggc ggagggagac
     7561 gggccgtacc cccagagggc cgcgctctcc gtccagttcc acacccgggt gtcggtcggc
     7621 cagtcccggt cctgcggcct caccgcgttt cgggacggcc gctcgccggt gacaccggcg
     7681 ccatccgagc gggggcgagg ggcgatccgt acgtaggtgt gtgtcgtggc ggccatgtcc
     7741 tgtcctcgct cttcgaccgg cggtgcggat gcagatacgg attggggggg aaggtttcag
     7801 gcggcgacgc cggcgttgac ggtgactggg atgttgtcgc gtgtggcctt ggagtacggg
     7861 cagatctggt gggcggcctc ggcgagctcc tgggcggtgg cctggtcgac gccgccgagg
     7921 acggggttga ggaccgcgga gagggagaac ccgccgtcgt cgccgtgggt gagcgttatc
     7981 tcggcggtga tggccgtact ggtaaggcgg atcctgcgag tggtggccgc gcggcgcagg
     8041 gcgccgagga agcaggcggc ccagccggcg gccacggagg agcggacctg gccgccgttg
     8101 cggccttctc cgtcgacgtc gacaacggcg gtgtagctga ctgccatggc tgatgctcac
     8161 catctgggcc ggaaggtctt cggactccgg ttgagccgaa tgtctacgac tcgactcgtg
     8221 cgcctacagc cccaggtcga gggcgaggca tgagtagaac ttccacgagc cttcggggtc
     8281 gtacgatccg ttcgccctgc cggccggatc ggcttcgacc gcttcggtca tgtcgtcgaa
     8341 acgtatgcgc tcgggaagct tgccgaagcg cgcgtgtcga accgccgcct cggcagcttc
     8401 cgtggtgagt cccttgttca tgaccgtgct ccacttcgtc gatcgcggac ggcgtcccgc
     8461 ttgccctgga cagatctcag catgcccctc catgcgtcac ccgtcaagcc ggtgacgaag
     8521 gaggatgtga gtcgccacac catggcgtcg gccctcgagc accgcacgtc agcctgtccg
     8581 tccagaggtg accgcgcggg cagtaccctt cagctgcccc aacggccgct cccccaggtc
     8641 gcataggtcc tcccggtggt accgaaggag cccccgggca gcactgcacg ggtgagattg
     8701 gctccccact ggctggtgct gggcactgac gaccagaggc gtgtcggcgt caagccttcc
     8761 ggtgcgtacg gttcggggtc agacggtgat ggtcttgtac tcggtgtagg tgccgaggcc
     8821 gactgccccg tactcccggc cgatcccgct cgccttgaag ccgccgaacg ggccgtcgaa
     8881 ggcgacggag gcgccgttga ccgtcacagt gccggtacgg atacgacggg ccaccgccag
     8941 ggcgtgctcc tcgtcggcgg accagacgcc gccggacagg ccgtactccg agtcgttggc
     9001 gatccggacg gcgtcgtcct cgtcgtcgta ggcgatgacc accaggaccg ggccgaagat
     9061 ctcctcctgc gcgatccgca tggagttgtc gacgtcggcg aagacggtcg gggtgacgta
     9121 gttgcccttc tccaggtcct cggggacctg agggccaccg gtgaccaggc gggcgccctc
     9181 ctcgatgccg agttggatgt agccgcgcac ccgttcctgc tggtcggggc ggatcatcgg
     9241 gccgatgaag gtgtcgggct cgttcgggtc gccgaccttc aacgactcga ccagctcctt
     9301 cagggcggcc accacctcct cgtaccggct gcgcggggcc aggatgcggg tctgggcgat
     9361 gcaggactca ccgttgttga gcagcgaacc gaacttcagg cccgccacgg ccctgtcgat
     9421 gtcggcgtcc ggcaggatga cggcggcgga cttgccgccc agctccagac tgacccgctt
     9481 gagctgctcg cccgcgatcg cggcgatacg gcggccggcc cgcgtcgagc cggtgaaggc
     9541 gatcttgtcg acatccccgt gggagaccag gtactcgctg gtctcccggt cggcgggcag
     9601 cacgctgatc acgccctcgg gcaggccgac ccgctccagc aactcggcca ggaaacccat
     9661 gctgagcgag ttctccggag acaccttgag aatcacggag ttaccggcga gcagagcggg
     9721 gatgatcttc gaagtggccg atgagaacgg cgagttccac ggaatcaccg cggccacgac
     9781 gccgaccgcc tcccggcgca ccacactgcg caccggggac tgggggtcgg agggcgcgag
     9841 cgtctcctcc caggcgaact cctccgccgc cctcagatag gcgttcgcct gccgggtcag
     9901 gcccggctgg ccggcccggg tgaaccagcc cgccgaaccg ttctccagtg agatcagccg
     9961 cgcgacacgc tccgcgttct cctcacgcag cgcgttgaac cgccgtaggg cggcgatgcg
    10021 ctccgcgggc ggagtcaggc gccacacacc ctcctcgaat gaggctcgtg ccgcggctac
    10081 cgcctggtcc acgtccgccg gtcgcgcctg taccgcacgg ccgatcactg accggtcgtg
    10141 cggcgagggg atgtcgagcg gttccgggtc gctcggctcg acccagctgc ctccgacgaa
    10201 gagccggtcg taggtgatca tgcgcttctc tcttcccgtg cctcaggtac ttcaggtgca
    10261 gttccttgac cgctccctct aattgtcact tcaatgtagc acttcaggca tctatattct
    10321 caaggtgtct cacaaagctg gaccttcttc cgcaccacag gcgctgttga gagatgagag
    10381 cgggcgagag gttggaacac ctgccatgct cgtcacctgt ttgacaggtg acgagcactg
    10441 tgcgagggtc gcctcgccgc aggcttacca agcacgggcc gggtcatcgg aatcgcacga
    10501 cggaggacca gacatgatca acaggcgtac cttcagcaag gccgtcggcc tgggcaccgg
    10561 cgcggccgcg gtctcgctgg caggcctgca aaccaacgct gccgccacga ccgccacgac
    10621 cgccttggac gagccgggcg gcggccccac gcccgcggtg cccagcatca cccccggcac
    10681 ccacaccgag ttcggcacgc tcaagcacgt caaggcgggt gtcctggaca tcggttacgc
    10741 cgaggtcggc ccccagcacg gcccggtcgt cgtcctcctg cacggctggc cgtacgacat
    10801 ccacagcttc gtcgacgtcg ccccgctcct ggccgacctg ggctaccgcg tcctcgtccc
    10861 gtacctgcgc ggccacggca gcacccgctt cctgtcccgc cacaccccgc gcaccgccga
    10921 gcagtccgcg atcgcgttgg acatcatcgc cttcatggac gccctgaaga tcgagaaggc
    10981 cgtcctcgcc ggtttcgact ggggctcgcg caccgccgac atcatcgccg ccctgtggcc
    11041 cgagcgcgtc aagtcccttg tgtccaccag cggttacctc atcaccgacc gcaagatgca
    11101 gctggagccc gccgctgcgg gcgtggaaca caactggtgg taccagtggt acttcgccac
    11161 cgaccgcggc gtgaaggcca tggagaacgt cgacgagcgc atcgcgctgt gccgctacgt
    11221 gtggaccctc gtctccccca actggaactt ctccgacgcc accttcgcgc gcacggccga
    11281 tgccttcagg aaccccgact acgccgcgat cgtcctctac aactaccgct ggcgcatcag
    11341 cctgatcgac ggcgaccggc gctacgaccg ttacgagaag cagttggccg cacagccctc
    11401 catcggggtc cccaccgtca ccctcgacgc cgccctcgac ccgttcaccg caccgggcga
    11461 cgggtccggt taccgcagcc acttcaccgg gccctacctg caccggacga tcgcgaacat
    11521 cggtcacaac ctgccacagg aagcacccac cgtcttcgcc caggccgtgg tcgacgccga
    11581 ccgcctctga ggggcggcca gttccgagcg ccggcagcct tcaggtgtgg gggcgcaggt
    11641 acatcccgtc gcggccaccg agcggcccgg ccctcaatca cccaccggcg gggacagcct
    11701 gtccacgttg cacgcgctgc tgcctggcaa ccggcgtccg tgatccgctc cgcccggagc
    11761 cgatctgcat gctgatctgc atgccagatt catcaccagt caaagcggtg actggatccg
    11821 gcgagaccga acaccgtaag taccgagaag aatttcctga gaggggtttg tcgtggtgag
    11881 tatcaagggt ggacgcaagc ggctgttgac gggggcggtc gcgacggccg cagcggggct
    11941 cgcgctcggc gcgttcgccc tcagcggcac cgccaacggc gcgaccgaga cggccgatgc
    12001 tgccggagcg gccaagcacg ccaagcccac catcatcctg gagcacggag ccttcgccga
    12061 cggatccagt tggaacggcg tcatcgccga cctgcgcgcc gacggctacc cggtcgtcgc
    12121 cgccgccaac ccactgcgcg gcccggcctc cgacgccgcc gccctgcgca cggtcctcga
    12181 ccacgtcaag ggaccgaaga tcgtcgtcgg ccactcctac ggcggcaacg tcatcagcgc
    12241 ggccgccaca gccgcacccg aggtcaaggc tctggtctac gtggccgcct tcctgcccgc
    12301 ccccggcgag agcgccctgg agctcacgaa caagtacccg ggctccacgc tccccgccgc
    12361 cctcgacccg gtcacctacc agcaggccga cggctccacc gccaccgacc tgtacatcca
    12421 gcaggacaag ttccaccacc agttcgccgc cgacgtaccg gccgggcagg cagccctgat
    12481 ggccgccgag caacgtccca tcgcccaggc agccctggag gagaaggcca ccaccgcggc
    12541 ctggaagacc aagcccagct gggacatcat caccaccgaa gacctcaaca tccccccggc
    12601 cgtgcagcgc ttcatggcca agcgcgccca cgcgcacacc accgaggtcg ccgcgtccca
    12661 ctccgtcgcc gtctcacacc cacatctggt ggccgccgtg atcgagcgcg ctgcccgcgc
    12721 aactgtccgc tgacacccct agnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12841 nncgccctcg ggcagcacgc cggacctcgt cccctgaacc cgcaggccgt cgtgtacaga
    12901 cagaccatgc gccacgcccg ggagcgagag gtccctcagg gtggcctggt ctcagccctt
    12961 gagcgcatag aagcgcatcg gggagttggg ctcgaaaccg atgcgcggat acaccggtgc
    13021 cccggcggcg gtcgcgtgca gggttgccct cgtgaggccg gtggcgcggg caccctcgta
    13081 cagcgccttg cgggtcaccg cctcgccgta accgcggcgc tgccagccgg ggtcggtggc
    13141 gacgagcacg acgaagagcc tgccctgggc ctcgacggtg gcggcgcagg cgaccggtgt
    13201 gccgtcccgc agcgccaggt acgcgtacac ctcctgcttc cacagggcgg agccggccag
    13261 tccgtcgcgg ccgtcctcca gggggaagcc gtaggcgcgt gaattgaggt ccgcgtaggc
    13321 caggaggtgt tcgtcggtgg tgacccgctc gaacgtcagg tccgggtggt ggggttcagg
    13381 gatgggcagc aggtcgccgg ccataccggt gccggggaag gcgtaggcca ggcccgcgcg
    13441 ttccgcggcc tcttccaggg ccgcgcgtgc gtcgtcggcg agcagatcct cgaacagcca
    13501 caggaagccc ggttgccgtt tggaccccat gatgtccgcc gcctgtcgca gccgcttctc
    13561 caggagcgtc gcgtcggtcc ccgtctcggt cagggtgacc gcgttccaga aggcgaaacg
    13621 gcagtcggcc cagcggacgg cgagccctgg cagatcccgt acgtcggcct gttcgtcccg
    13681 gtcgagcacc atggcacgcc agccggtggt cagctgggac acggattcga tcgcggcggt
    13741 caggttgctc acagcagtcc ctcgtttcgt cgtgtcctgc ggaatgttct gcaccgggta
    13801 cgacgatctt tgccttccgg ggtgcggcga caccgctgtt cacgtcagag agcgtccagt
    13861 tccggacagc cccgaaccgc agctcggcca gccctcgatc aacgcctggg cgccgagccc
    13921 tgagtgacac gggccgcggc ggagcggcgg gccggcggcc actccgcgtc gacggccgca
    13981 aggccggagg tgcacctgta ccaggcccgg ctgcgcactc cggtggcgga cggcacggca
    14041 cggcacccat gtggtggccg agaaacgtgg tccacgggcc caccgccagg tctttgacgg
    14101 cgtcggcccc gctgtgggcg caccgactgc actcgttgta ggacacccag ctcaagcggc
    14161 tttcggaggc gactccgcag gacaggacag cgacgcctgg cccgcgtcgt gggcgcccgg
    14221 agcgctccgt cggccggcac ccggtggggt gtcggccggt caggggcatg ggagccgccg
    14281 ggtcaggcgg cggcctggac ggaatccttg gcaggcgcgg ggtccgagtg gtcaagggcg
    14341 gcggtctcgc cggtcctgag tgccggcttc aggaacaggg nnnnnnnnnn nnnnnnnnnn
    14401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14521 nnngaagccg gtgttgagga gggtgccgaa aacggcgacc ccgaaggcgg cgccgatgga
    14581 gcgggcgaag gtgacgacgg cgctggcggc gccgaggtcg gcggcgggca cgctgttctg
    14641 gacggtggtc agcacgacca tgggcaccat gccgatgccg acaccggtga tcaggaagta
    14701 gacgctcagt acgagggcgt tggtggccgc gccgatggtg cccagcagga gcagcccggc
    14761 aaggttggcg accaggcccg ccaggaggat cgtccgcagc cgaccgactt gtgcggccca
    14821 gcgtccggcc agggactggc tgacgaccag accggcgacc agaggcagca tgtgaacgcc
    14881 ggagagagtg gccgagactc cgtggacgat ctggaggtag gtcggcaggt agaccagcac
    14941 ggagaacatc gcggcgttgg cgaagaaggc gatcagcgag gagaacacca cggtccggga
    15001 ggcgaacatg gccggcggca ggaccggggc ggcggcgtga cgctccaccg gcaccagcag
    15061 cacggccagc acgatggtgg cggcgatcag accgacgatg gccggcgagc cccagcccca
    15121 gcgctccccg aaggaggtga cgagcaccag gccggtggcg agggcggcca gcacggtggc
    15181 gccgaggtag tcgacgcggg cccgggtacc ccgagtggcg gcgggcagcg cccgggcggc
    15241 gatggccagg gcgacgatgc cgaccggcag gttgatcagg aaggcccagc gccaggacag
    15301 ttgatcggtg aagacgccgc ccagcagggg gccgacgatg ctggcgacac cgtagaccga
    15361 gccgaacatg ccctggtagc ggccacgttc actcggggcg acgatgtcgc cgacgagggc
    15421 gaaggtcagc acgatcatgc cgccgccgcc cacaccctgc agcacacggg cgccgaccag
    15481 ttcggccagg ttctgtgcca ggccgcaggc cacggaggcg atcaggaaga ccgaggtcga
    15541 ggccagatac agcggcctgc ggccgaacat gtcgcccagc ttgccccaca gaggtgtgac
    15601 cgcggtcgac gcgaggaggt aggcggcgct gacccatgcg atgtcgtcga aaccgttgag
    15661 gtcctcggct atccggggca acgcggtcga gacgatcgtc tggtccaggg ccgcgagcag
    15721 gaccgccagg accagcgcgc tcatcgcggc ggcgacacca cccgccctgg gtgaggagga
    15781 gttgtctgcc ttcgtcatcg gaagcaccct tctagagact catcaatctg gcactaacag
    15841 atctttctgt cactagaatg tagcacttag agaggagcct tctactcccg agaggcgcta
    15901 gatgtctcag gcatcacatc tcgccactag aatcagtgcg gtgagagccg atgcagcgcg
    15961 caatctcgaa gccgtcctga ccacaggcgc ccgcatgctc gccgccgacc ccggcgcgag
    16021 catcgcgagc atcgcggccg aagcgggggt cgaccggcgg accgtctacc gccgcttcgc
    16081 ctcccgcgaa gacctcctgg cggccatcta cgaagcccgt ctcaccgcca tcgagcacgc
    16141 catcgaagac gcgcggctcc gcgaggcacc cgtcgccgtc gccctgcacc gctacgtcga
    16201 gaacatcatc accgtcaacc gcacctggcc ggtcgacctc gcccgcatgc tcaccgacca
    16261 cagcgtccac gcccggcgcg atgcggccgt cgaggaggtc gacaccttcc tgcgacgtgc
    16321 cacggacgaa ggcctgctgc gctccggtct gccgcagggc tgggcgagcg tgctgctccc
    16381 ccagctcatg cacctggtct cccgccaact gccggaactg agcgcgggac agggggcgga
    16441 cgtcgtcgtc gacaccctcc tcaacggcct cgggacttca tga
//
