LOCUS       reptomyces_RBGC_673681 17079 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_673681
VERSION     Streptomyces_RBGC_673681
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_003675345.1
  ORGANISM  GCF_003675345.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..459)
                     /protein_domains="PF12680"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394423"
                     /pseudo=False
                     /translation="MSDLTVERVRSAFEALGSGDRDRMLEFWDENVRFEIPGNHVQAGW
                     HEGLDAFLGFLGTVGELSGGSYKAENLTITVNPEDGYSVDVNTNWALRAGAPEDSTSPY
                     HLLDVTAMHLLRWENGRIVEGRGVILGDGLSTSALWWSPIGPDGKRAA*"
     CDS             complement(558..1786)
                     /protein_domains="PF00441"
                     /protein_domains="PF02770"
                     /protein_domains="PF02771"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394424"
                     /pseudo=False
                     /translation="MDFALDDRTRQLQDRLLAFMDAHVLPAESVLAEQLAAGGDRWARP
                     AVVDELKAEARRQGLWNLFLPHSPTGAGLSNLQYAPLAEITGRSPFLAPEALNCSAPDT
                     GNMELLEMFGTDVQRKRWLEPLLDGAVRSAFCMTEPEVASSDATNIATRIERDGDGYVV
                     NGRKWWSSGALSPHCELLVVMGKTDPGAERHRQQSMILVPKDTPGVEVRRGMTLFGYDH
                     GPHGGHAEIVFRDVRLPAEALLGEEGGGFAMAQARLGPGRIHHAMRLIGMAERGVELMC
                     RRVVSRVAFGSALAEQGVVQEWIAEARVRIEQARLLVLKTAWLMDTVGNKGAHTEIQSI
                     KIATPALAEWVLGKAIQAHGAGGVSQDFPLAELWAHARSLRLADGPDEVHRRSLARREL
                     RPYRDAARTA*"
     CDS             complement(1890..2956)
                     /protein_domains="PF01636"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394425"
                     /pseudo=False
                     /translation="MSLSAEHPAPPPAAPLPRGVDTAALTAWLARELPGAFPEGPRLSL
                     IAGGRSNLTYRLTGGERPMVLRRPPLGHVLSTAHDMSREYRVMSALAGSAVPVPRMRAF
                     CSDLAVLGAQFYVMDEVDGVVHRSAAELAALDPAEGRALGLALADTLATLHTVDPGSVG
                     LADFGRPEGFMARQVARWRRQLAASRTRRLPGVTQLAERLEAGLPTAPPPALVHGDYRL
                     DNVMFAARGTDRVAAVLDWEMATVGDPLADLGMFCVYWDGLTGLGEAVPPAPGACPGWP
                     DRAELVARYAARTGLPLDALRWYVAFGFFKIAVILEGIHCRYAKGLTLGEGFEGIAAAV
                     PELIRRGHATFDGEH*"
     CDS             complement(2957..3711)
                     /protein_domains="PF13561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394426"
                     /pseudo=False
                     /translation="MRRFDGKVALVTGASRGIGKACAARLVAEGARVCLTARRPEPLAE
                     VVAELGGPRHALAVAGHADDEAHRAEAVARTVEAFGGIDVLVNNTAVNPAYGPVLAMEA
                     DAVRKVFDVNVHAALDLIRRVRESDPSREGRAVVNVTALAGLRTAHGIGVYGASKAALI
                     HLTAQLAREEGPGMRINSVAPAVIRTRFAAKLYEEQEEQLAKEYALGRLGTPEDVAAAV
                     AFLASGDAAWVTGQTLAVDGGIILQGGGI*"
     CDS             complement(3836..5433)
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394427"
                     /pseudo=False
                     /translation="MTEKTSTARPALTLLTVSIATILLPMSLTGASVAMPGASEDFHNG
                     LAAGQWIVNGYDLTFASFMLAAGSFADRFGRRRLFALGSAVFAVCSLVSAVSNGIVMLD
                     ICRALAGVGAAAVITAGSAILAHTFEGAARARAFGVFGTAVGAGLAFGPFAAGALQTSF
                     GWRAIFLVPAIVGAVVVALSLFLAESSDPDAVRVDWLGTVTFTGSLAFLILALLQGPQT
                     GWADPVNLVSYVLAAALLAAFVMVELRQERPMFDLSLFRQPQFVSLCVAVVSLVFGFTP
                     LLVYLPSYLTAVNAESTFHAGVDLLMLTVPTLVFPLVTGYLLRWVPLRHMVSLAVALTA
                     IGCGWLVVLEPGAGNWTVLGPFLIIGTGVGISFGVMDGAAVSSVDSARAGMAAGMFNTM
                     RLAGEAIAIAVVGSLLVSATRSELDGKLGGFDGTYANDPGGLADKLNQGQLEGPAGTVS
                     AASRAAFTEVAKAGYTGALHQVLWFLAAFCAVATVLVAFVGARSQKKSAAEESAEPTAE
                     AAAEAAARESQPSAV*"
     CDS             5784..6724
                     /protein_domains="PF00107"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394428"
                     /pseudo=False
                     /translation="MRALEPTGLDEAMVAFAEVPEPEPQADEVVVEVDAFSVNRGETFL
                     LASPRPGWRPGKDVAGRVVRAAADGSGPAEGSRVVAHPPAAGWAERVAVAARSTAVLPK
                     SVDAATAAVLPLAGITAVRLLRQSGAAAGDRVLITGASGGVGHYVTELAAAAGIEVTAV
                     TATPERGERLAALGAAQVVQSVAEAKGPFQVVLESVGHEVLPATLPLLTSGGRLIWFGQ
                     ASRQPSALNFFHFFRKPDQDPFAVTLEHFDYTRGERSYGEELAELVDLVATGRLHPEIG
                     LRGDWTGAAEAIAALRARTVRGNVVLTTGEGA*"
     CDS             6922..7838
                     /protein_domains="PF00126"
                     /protein_domains="PF03466"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394429"
                     /pseudo=False
                     /translation="VELRQLRYFVTVSEERHFGRAAERLHIGQPAVSQQVRRLERELGV
                     ELFDRSPRHVRLTPAGETFLPAARAVLDAELRAAAAVAEFAGAHTGILRLGTSTGLGAR
                     LDRILDVLAQRAPHVSVELNSAPARDRLDRVAKGQLDASFVRGSGSGGALCWHPVWQEP
                     LAVAVPAGHPLAAAGHASLADLAALPLRLTSRRSNPALVDTVLSACRDAGFDPVPGPSS
                     ARTLEDTLAAIGTGAPTWTVVYAEHARQLRSTSRIAFLPLAGAGLAIPTSLVVRRSAPT
                     PLLPLLLDACTQRPLPAGVRDHES*"
     CDS             7965..8146
                     /protein_domains="PF01361"
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_6394430"
                     /pseudo=False
                     /translation="MPIVTVQQGPRDTELKRELVERITDAFVDAYKIPADTVQVWIHEV
                     PADSWGVSGKLIADS*"
     CDS             8607..9334
                     /protein_domains="PF00196"
                     /protein_domains="PF00072"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394431"
                     /pseudo=False
                     /translation="MAPVMTRERSRRIVVVDPFPLSRRALVGLLRDRDGGQVVGEAGSR
                     QEALEECALRLPDVVITDIDLLGPADGIRLCEQVKRLAVPPLVLVYSGTAAPGALAECL
                     THGADSFVHRTAPVERLISAIDLLFEGKPLWYFGELTPGTHTATLPCETVNGLLTPREQ
                     QILGLLLRRHSNEEIAEDLHLARQTVKNYVSNILQKLGVSSRRELLTGKIPTQPAARAP
                     LPGRARDLVATRSERGGNRP*"
     CDS             9332..10308
                     /protein_domains="PF00107"
                     /protein_domains="PF08240"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394432"
                     /pseudo=False
                     /translation="MRSVRFTEYGGPEVLALDDRAAEPVPGEDEVLVEVTHAGVTFADV
                     MFRRGQIPVGLPFAPGLEAVGTVRATGSAVTGVRAGQRVAALCLGGGALSERVVAKAGL
                     TVPLEGALAGLGSAAAAGMITNGVTAWGLVHAAARIGAGDTVLVLAAAGGVGTAVAQLA
                     KAAGARLVIGAVGSPEKAARLTDPAYDAVTTYASLAAEVERHTGERGVDHAFDSVGGEP
                     RTAVDKLLAPFGRHVIYGDAAQQDTQYPGNHVWFTNSALVGYNLGDVAGRDPALLRSHL
                     ESALRALAEGRLRGEPATAAPEEIAKVHTELESRASTGKYVVAW*"
     CDS             complement(10597..11666)
                     /protein_domains="PF00877"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394433"
                     /pseudo=False
                     /translation="VAAQHRKHRKPGRRLLGGTPGRAAATLAVTGATAATALGGTGQAA
                     PEARPGEVRAQVDRLYRQAEVATEKYNGAKEKADAARTSLRGLREEAARTAERLGSTRA
                     GLASLATAQYREGTLDPALQLVMSADPEEYLRGTAVAERASHRQAAAVGEARGQLRKLA
                     RLRGEADRVADRLGTQQSELARSKRAVQEKLGRARQLLDRLTAEERAAATREDGRASRE
                     QARTAAPAAAPAPTAAAPGSRAGAAVAYAYRALGKPYVWGATGPNSFDCSGLIQAAYRA
                     AGVSLPRTTYSQINAGTRIGRGQLRPGDLVFFYSGISHVGIYVGGGKMIHAPRPGAPVR
                     IAPISRMPFAGAARVA*"
     CDS             11979..12433
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394434"
                     /pseudo=False
                     /translation="MLGGGEPRRGPGTGLPASRDPPPVPPGAPVTLPAMDVLIHLFVGL
                     HIIGIASLLGGFLTQMKALGEGTARFSPAMLHGALTMLVTGVILVGLNQADDNTVNNVK
                     IGVKLALLVVILGLVYVKRDEERADKAQFGLVGGLTAANVFIAVLWT*"
     CDS             complement(12576..13861)
                     /protein_domains="PF00877"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394435"
                     /pseudo=False
                     /translation="MAHQPSQPLHELASVPGGQPVRTGETAPDPGARNVRHALRGRPTE
                     GVAALASHRKPRSPRVVPGPAVGLTTAALTSVALLSQSATAAPEKPRPSLEEVRKKVDG
                     LYHEAGVATQKYNAAKERADAQRRKVDGLLDDVARRTEKLNEARAELGSFAAAQYRTGG
                     VSGTATLLLADDPAQYFDQTQLMHRLTGRQKKAVDDYQSQQLSTARKRAEATRSLAKLT
                     GSQRSLKSAKQDVQAKLGTARTLLSQLTAKEKARLAAIEKKKEEEARRKAAALARKQAE
                     ERERREREERENDEGGTGGGEETPGTPGGASAAQGEQALAFARQQIGKPYVWGATGPDS
                     FDCSGLTLAAWKAAGITLPRTTWDQVKTGTTIPVSEARPGDLVFFYDDISHVGLYLGDG
                     TMVHAPKPGADVREESIYYMPIHSVVRPG*"
     CDS             13995..16477
                     /protein_domains="PF00580"
                     /protein_domains="PF13361"
                     /protein_domains="TIGR01073"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394436"
                     /pseudo=False
                     /translation="MSSLFDDSFLADLRAPREEAPPPPEDPEGEEREDLPDDLFGGKYD
                     VPPPRDAHYRDGAPRPAVDSAALVEGLNEQQRAAVVHSGSPLLIVAGAGSGKTRVLTHR
                     IAYLLAERGAHPGQILAITFTNKAAGEMKERVEQLVGPRANAMWVSTFHSACVRILRRE
                     SKKLGFTSSFSIYDAADSKRLMALVCRDLDLDPKKFPPKSFSAKVSGLKNELIDEEDFA
                     AKAADGFEKTLAQAYAMYQSRLREANALDFDDLIMTTVNLLRAFPDVAEHYRRRFRHVL
                     VDEYQDTNHAQYALVRELVGREPDPEAEPAPDAAPPPPAELCVVGDADQSIYAFRGATI
                     RNILQFEEDYPDATTILLEQNYRSTQTILTAANAVIERNESRRPKNLWTNAGAGAQITG
                     YVSDTEHDEAQFVAEEIDRLTDAGEAKAGDVAVFYRTNAQSRVFEEVFIRVGLPYKVVG
                     GVRFYERKEVRDVLAYLRVLANPEDSVPLRRILNVPKRGIGDRAEAMIDALSQREKISF
                     PAALRRVDEAYGMAARSANAVKRFNTLMEDLRTVVESGAGPATVLEAVLERTGYLAELQ
                     SSTDPQDETRIENLQELAAVALEFEQETGEGEESATLSDFLERVALVADSDQIPDEEDG
                     NGVITLMTLHTAKGLEFPVVFLTGMEDGVFPHMRALGQTKELEEERRLAYVGITRARER
                     LYLTRSTLRSAWGQPSYNPPSRFLEEIPAAHLEWKRTGAPAPVSSGPASGVAASLSSSR
                     ARGGAGGASGFATRRAGEKPVVSLAVGDRVTHDQFGLGTVVGVKGTGGNAEATVDFGDP
                     KPKRLLLRYAPVEKL*"
     CDS             16565..17079
                     /protein_domains="PF06718"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6394437"
                     /pseudo=False
                     /translation="MTTYTPLPIPPAALAELRGTDDSGRPMRPYTAREDGVPLDCVGSP
                     LRCCLRPVEAGERVALVSYAPLRRWARTTGATPGAYDEAGPVFLHAEECPGPRGEGYPF
                     ARPGALRTLRRYDSAGHIVGGRLFEIPQEAGPGFDKALGEAFADPRVALVHVRAVEYGC
                     FQFEVRRP*"
ORIGIN
        1 tcaggcggcg cgcttgccgt ccgggccgat cggggaccac cacagcgcgg aggtcgacag
       61 gccgtcgccc aggatgacgc cgcggccctc cacgatgcgg ccgttctccc agcgcagcag
      121 gtgcatcgcg gtcacgtcga gcaggtggta cggcgaggtg ctgtcctcgg gggcgcccgc
      181 gcgcagcgcc cagttggtgt tcacgtcgac cgagtagccg tcctcggggt tcaccgtgat
      241 ggtgaggttc tcggccttgt agctgccgcc ggagagttcc ccgacggtgc ccaggaatcc
      301 gaggaatgcg tcgagcccct cgtgccagcc ggcctgtacg tgattgccgg ggatttcgaa
      361 gcgtacgttc tcgtcccaga actccagcat gcggtcgcgg tcacccgagc cgagcgcctc
      421 gaatgccgaa cgtactcttt cgacggtgag atcggacatt gtttctccct cagtgctttc
      481 ttgttacggg gctgtgattt ccgcgggggc ggtcgcggtt tcgtattccg ccccgcgggg
      541 atgtcgccgc gggctttcag gcggtgcggg cggcgtcgcg gtaggggcgc agttcgcgcc
      601 gggccaggga gcggcggtgc acctcgtcgg ggccgtcggc caggcgcaac gaccgggcgt
      661 gcgcccagag ttcggccagc gggaagtcct gcgagacgcc gcccgcgccg tgcgcctgga
      721 tggccttgcc gagcacccac tcggcgagcg cgggggtggc gatcttgatg gactggatct
      781 cggtgtgggc gcccttgttg cccacggtgt ccatcagcca ggccgtcttc aggaccagga
      841 gcctggcctg ctcgatccgc acccgggcct cggcgatcca ctcctggacg acgccctgct
      901 cggcgagtgc gctgccgaag gccacccggg agaccacccg gcggcacatc agctcgaccc
      961 ctcgctcggc catgccgatc agccgcatcg cgtggtggat gcggccgggc ccgagccgcg
     1021 cctgcgccat cgcgaagccg ccgccctcct cgccgagcag cgcctcggcg ggcagccgca
     1081 cgtcccggaa gacgatctcg gcgtgcccgc cgtgcggacc gtggtcgtag ccgaacagcg
     1141 tcatcccgcg ccggacttcg acgcccgggg tgtccttggg caccaggatc atgctctgct
     1201 gccggtggcg ttcggcgccc gggtcggtct tgcccatcac cacgagcagc tcgcagtgcg
     1261 ggctcagggc gccgctggac caccacttgc ggccgttgac cacatagccg tcgccgtccc
     1321 gctcgatccg ggtggcgatg ttggtggcgt cggaggaggc gacctccggc tcggtcatgc
     1381 agaaggccga gcgcacggcg ccgtcgagca gcggctccag ccaccgcttg cgctggacgt
     1441 cggtgccgaa catctccaga agttccatgt tgccggtgtc gggggccgag cagttcagcg
     1501 cctccggggc caggaagggg ctgcggccgg tgatctccgc gagcggcgcg tactggaggt
     1561 tgctgagtcc ggccccggtc ggggagtgcg gcaggaagag gttccacagt ccctgccgcc
     1621 gggcctcggc cttcagctcg tccacgacgg cgggccgcgc ccagcggtcg ccgcccgccg
     1681 cgagctgctc ggcgaggacg gactcggcgg ggaggacatg cgcgtccatg aaggcgagca
     1741 gccggtcctg cagctgccgg gttctgtcgt cgagtgcgaa atccatggcg ggttgccgtc
     1801 cttgccgccg ccgaacatcc cgtgcggaca cggcggttcg gcagctcgta cgagtgagga
     1861 aggagaagga ggggaggcgc gcggggcctc agtgctcgcc gtcgaaggtg gcgtggccgc
     1921 ggcggatcag ctcgggcacg gcggcggcga tgccctcgaa gccctcgccg agggtgaggc
     1981 ccttggcgta ccggcagtgg atgccctcca ggatcacggc gatcttgaag aagccgaagg
     2041 cgacgtacca gcgcagcgcg tccaggggca ggccggtgcg ggcggcgtag cgggcgacga
     2101 gttccgcgcg gtccggccag ccggggcagg cgcccggggc gggcggcacg gcctcgccga
     2161 gtccggtcag gccgtcccag tacacgcaga acatgcccag gtcggccagc gggtcgccga
     2221 cggtcgccat ctcccagtcc agtacggccg cgacccggtc cgtgccgcgg gcggcgaaca
     2281 tgacgttgtc caggcggtag tcgccgtgca ccagggcggg cggcggcgcc gtcggcagcc
     2341 cggcctccag gcgctcggcc agctgtgtca ccccgggcag ccggcgggtg cgggaggcgg
     2401 ccagctgcct gcgccaccgg gcgacctggc gggccatgaa gccctccggg cgcccgaagt
     2461 cggcgagtcc gacgctgccc gggtcgacgg tgtgcagggt cgccagggtg tccgcgaggg
     2521 cgaggccgag cgcgcggccc tcggcggggt ccagcgccgc cagctcggcg gcgctgcggt
     2581 ggaccacgcc gtccacctcg tccatgacgt agaactgcgc gccgaggacg gcgagatcgg
     2641 agcagaaggc ccgcatccgg ggcaccggca ccgcggaccc ggcgagcgcg ctcatcacgc
     2701 ggtactcgcg gctcatgtcg tgcgcggtgg acagcacatg gccgagcggc gggcgccgca
     2761 gcaccatcgg ccgctcgccg ccggtgagcc ggtaggtgag gttggaccgg ccgcccgcga
     2821 tcaggctcag ccgggggccc tcggggaagg cgccgggcag ctcgcgggcc agccaggcgg
     2881 tgagcgccgc ggtgtcgacg ccgcgcggca ggggcgcggc cgggggcggg gcggggtgct
     2941 cggcggagag gctcatcaga tgcccccgcc ctggaggatg atgccgccgt ccacggccag
     3001 ggtctgcccg gtcacccagg cggcgtcccc ggaggccagg aaggcgaccg cggcggcgac
     3061 gtcctcgggg gtgccgagcc gcccgagcgc gtactccttg gcgagctgct cctcctgctc
     3121 ctcgtagagc ttggcggcga agcgggtgcg gatcaccgcg ggggccacgg agttgatccg
     3181 catccccggg ccctcctcgc gggcgagctg ggcggtcaga tggatcagcg cggccttgct
     3241 ggcgccgtag acgccgatgc cgtgggcggt gcgcagcccg gcgagggcgg tgacgttgac
     3301 gaccgcgcgc ccctcgcggg acgggtcgct ctcgcgcacc cggcggatca ggtcgagcgc
     3361 cgcgtgcaca ttgacgtcga agaccttgcg gacggcgtcc gcctccatgg cgagcaccgg
     3421 cccgtaggcg gggttcaccg cggtgttgtt gaccaggacg tcgatgccgc cgaaggcctc
     3481 gacggtgcgg gcgaccgcct cggcccggtg cgcctcgtcg tccgcgtgcc cggcgacggc
     3541 gagggcgtgc cgggggccgc cgagttccgc gaccacctcg gcgaggggtt cggggcggcg
     3601 ggcggtgagg cacacccggg cgccctccgc gacgagacgg gcggcacagg ccttgccgat
     3661 cccgcggctc gcaccggtga ccagtgcgac ctttccgtcg aatctgcgca tggggctttc
     3721 ctgttcggcg atcggaccgg gcgaggcacg gtcggtggag cggaaggtga ggagaggaag
     3781 agggtgcggt cgggggccgg gcccggcgtg cacgcgccgg gcccggccgc cggatcagac
     3841 cgcgctgggc tgggactcgc gggcggccgc ctcggccgct gcctccgcgg tcggctcggc
     3901 gctctcctcg gcggcgctct tcttctgcga gcgggcgccg acgaaggcca ccaggacggt
     3961 cgccacggcg cagaaggccg cgaggaacca caggacctgg tggagcgccc cggtgtagcc
     4021 cgccttggcc acctcggtga aggcggcgcg ggaggccgcg gagacggtgc cggccgggcc
     4081 ctccagctgg ccctggttga gcttgtcggc gaggccgccc gggtcgttcg cgtacgttcc
     4141 gtcgaagccg ccgagcttgc cgtccagttc ggagcgggtg gcgctcacca ggagcgagcc
     4201 gaccaccgcg atggcgatgg cctcaccggc gagccgcatg gtgttgaaca tgcccgccgc
     4261 cataccggcc cgcgcggagt ccacggagga gaccgcggcg ccgtccatca caccgaagga
     4321 gatgccgacc ccggtgccga tgatcaggaa ggggccgagc accgtccagt tgccggcgcc
     4381 gggttcgagg accacgagcc agccgcagcc gatcgcggtg agcgccaccg cgagcgagac
     4441 catgtgccgc agcggcaccc agcgcagcag gtagccggtg accagcggga agaccagcgt
     4501 cgggacggtc agcatcagca ggtcgacacc ggcgtggaag gtcgactcgg cgttgacggc
     4561 ggtcaggtag ctcggcaggt agaccaggag cggggtgaag ccgaagacca gcgagaccac
     4621 ggcgacgcac agcgagacga actgcggctg ccggaacagg ctgaggtcga acatcggccg
     4681 ctcctggcgc agttcgacca tcacgaaggc ggccaggagg gcggcggcca ggacgtatga
     4741 gaccaggttg accgggtccg cccagccggt ctgcgggccc tggagcagcg ccaggatcag
     4801 gaaggcgagc gagccggtga aggtgacggt gcccagccag tcgacccgga ccgcgtcggg
     4861 gtcgctggac tctgccagga acagggacag ggcgaccacc acggcgccga cgatcgccgg
     4921 taccaggaag atcgcgcgcc agccgaagga ggtctgcagg gcaccggccg cgaaggggcc
     4981 gaaggcgaga ccggcgccga ccgccgtacc gaagacaccg aacgcccggg cgcgggcggc
     5041 cccttcgaag gtgtgggcga ggatcgcgct gcccgcggtg atgaccgcgg cggcgccgac
     5101 tccggcgagc gcccggcaga tgtcgagcat gacgatgccg ttggagacgg ccgacaccag
     5161 cgagcagacg gcgaacaccg ccgagccgag ggcgaagagg cggcggcgcc cgaagcggtc
     5221 cgcgaaggag cccgccgcca gcatgaagct ggcgaaggtg aggtcgtagc cgttgacgat
     5281 ccactgcccg gccgccaggc cgttgtggaa gtcctcggag gctcccggca tggccaccga
     5341 ggcgccggtg agcgacatcg gcagcaggat cgtggcgatc gacacggtga gcagggtcag
     5401 ggctggacgt gcggtggagg tcttctcggt catgaatttc ctcatgaagt tcgacgagga
     5461 cgggcaggac ggcgcgacag gtgtccgcgc gcagcgcttc gccgggacac ccctgagggg
     5521 agttcccgcg gcggtgcggg gtgcggtacg tggagatgcc gagggaacgg cacggcgccg
     5581 ggcgcgacaa ccgggcgcaa ttaccggcct gtacaggtcg gcgattcttt tacgagctta
     5641 ggcagcaagg cgccgttgcg gatgggatca ccagtaccga attgcggccg cgaaacagta
     5701 ccggcggtac ctgtacgcga tgcctttccg cgcgcgagat tgggccgtaa aaagctcagt
     5761 gaagttcaga aaggaccccg agatgcgcgc cctcgaaccg acgggactcg acgaggccat
     5821 ggtcgccttt gccgaggtgc cggagccgga accgcaggcc gacgaggtgg tggtcgaggt
     5881 ggacgccttc tccgtcaacc gcggggagac cttcctgctc gccagccccc ggcccggctg
     5941 gcgtcccggc aaggacgtgg caggccgggt ggtccgcgcc gccgccgacg gctcgggtcc
     6001 cgccgagggc agccgggtgg tcgcgcaccc gccggccgcg ggctgggccg agcgggtcgc
     6061 cgtcgccgcc cgcagcaccg ccgtgctgcc gaagagcgtg gacgcggcca ccgccgccgt
     6121 gcttccgctt gccggcatca ccgccgtacg gctgctgcgc cagtccggtg ccgcggccgg
     6181 ggaccgggtg ctgatcaccg gcgcctccgg cggggtgggc cactacgtca ccgaactggc
     6241 cgccgcggcg ggcatcgagg tcaccgcggt caccgcgacc cccgagcgcg gagaacgcct
     6301 ggccgcgctg ggtgcggccc aggtcgtgca gtccgtggcc gaggccaagg ggcccttcca
     6361 ggtggtcctc gaatcggtgg gccacgaggt gctgccggcc acgctgccgc tgctcacctc
     6421 cggcggccgc ctgatctggt tcggccaggc cagcaggcag ccctcggccc tcaacttctt
     6481 ccacttcttc cgcaagccgg accaggaccc cttcgcggtg accctcgaac acttcgacta
     6541 cacccgcggc gagcgcagct acggcgagga actggccgag ctggtcgacc tggtggccac
     6601 cggccggctg cacccggaga tcgggttgcg cggcgactgg accggggccg ccgaggcgat
     6661 cgccgccctg cgcgcccgta ccgtacgcgg caatgtcgtc ctgaccaccg gcgaaggggc
     6721 ctgagcgcgg ccggagtcgc cgccgagcgg gtccggggcg ggggcccggg gccggacgga
     6781 aggccgcggg cccgcccccg gggaggggcc cgcggccgtg ccgccgcccc ggtgccgcgg
     6841 cctttacctt cgtcgccggt ggtccgccgg tctttctatg ctggcctggt tccgttgtct
     6901 ggaccggggg agtcggcatc gtggaactgc gtcagctgcg ctatttcgtc accgtctcgg
     6961 aggagcggca cttcggccgc gccgccgagc ggctgcacat cgggcagccc gccgtcagcc
     7021 agcaagtgcg ccgcctggag cgggaactgg gggtcgagct cttcgaccgc tcgccccggc
     7081 atgtgcgtct cacgcccgct ggtgaaacgt tcctacctgc ggcgcgggcg gtcctcgacg
     7141 ccgagttgcg ggccgccgcg gcggtcgccg agttcgccgg ggcgcacacc ggcatcctgc
     7201 gcctgggcac cagcaccggg ctcggggcgc ggctcgaccg catcctcgac gtgctcgccc
     7261 agcgcgcccc gcacgtcagc gtcgagctca actccgcccc ggccagggac cgtctggacc
     7321 gggtcgccaa gggccagctg gacgccagct tcgtccgcgg ctccggcagc ggcggcgccc
     7381 tgtgctggca ccccgtatgg caggagccgc tggccgtcgc ggtgcccgcg ggccatccgc
     7441 tggccgcggc gggccacgcc tcgctcgccg acctggccgc gctgccgctg cggctcacct
     7501 cgcggcgcag caacccggcg ctcgtcgaca ccgtcctctc ggcctgccgg gacgcgggct
     7561 tcgacccggt gccggggccc tcctccgcgc gcaccctgga ggacaccctc gccgcgatcg
     7621 gcaccggcgc cccgacctgg acggtcgtct acgccgagca cgcgcggcag ttgcgcagca
     7681 cctcccggat cgccttcctg ccgctggccg gggcgggcct cgcgatcccc acctcgctgg
     7741 tggtccgccg cagcgcgccg acgcccctgc tgccgctgct cctcgacgcc tgtacccagc
     7801 ggccgctgcc ggccggggtg cgcgatcacg aatcgtgatg actgccggtg ccggttgcgt
     7861 cttggtcggt ggccgaatcc cgggtggact tgaggtcatg cgggggctcc ggagaaccgg
     7921 gtcgcgcata tgtcttcctg taaatcctga ggagtattca cccatgccta tcgtcactgt
     7981 tcagcagggc ccgcgggaca ccgagctcaa gcgcgagctg gtggagcgca tcacggacgc
     8041 cttcgtcgac gcctacaaga tcccggccga caccgtgcag gtctggatcc acgaggtccc
     8101 cgccgacagc tggggcgtct cgggcaagct gatcgccgac tcctgagccg gtgaccggcc
     8161 cgtgcggggc gcctgcgaca cgctccgcac cggctggtcg gcgccgtgcg gcgggtccgc
     8221 ggggccgtgg tgcgggcccg gcgggtccaa gccttggcaa agggatccgt ggtggatcca
     8281 aggactggca aagcattcca aaagaatgag gggtgagtta agtcacgcgt gccggaatga
     8341 tctcctcggt cgccccgaat ggtcgaaata gcgggggttg gcgaggtcgg acgacaactg
     8401 gaacaagtta atccgggcat tctccttcgc ttgacgtggc ggagcgccgc gccatagttt
     8461 ccagcctcaa acatcaatcc cgcttatggc gggaaaatga tgcaccgata gtggccccgc
     8521 agaggtgaaa gttactcgcg ggaagttgtc tctttaacgg gttcgcgaac ccgtgaggtg
     8581 tgccaagtaa acgggggaaa cacacatggc acctgtcatg acaagagagc gaagcagacg
     8641 catagtcgtc gtcgaccctt ttccactgtc ccgcagagcg ctggtcggcc tgctgcgcga
     8701 ccgcgacggg ggacaggtcg tcggcgaggc gggatcccgg caggaggcgc tggaggaatg
     8761 cgccctgcgg ctgccggacg tggtcatcac cgacatcgac ctcctcggcc cggcggacgg
     8821 catccggctg tgcgagcagg tgaagcggct ggccgtgcct ccgctcgtgc tcgtctactc
     8881 gggcaccgcg gcgccgggcg ccctggccga gtgcctcacc cacggcgcgg acagcttcgt
     8941 gcaccgcacc gccccggtcg agcgcctgat cagcgccatc gacctcctct tcgaggggaa
     9001 gccgctctgg tacttcggtg agctgacgcc gggcacccac accgccaccc tgccctgcga
     9061 gaccgtcaac ggcctgctca ccccgcgcga acagcagatc ctcggcctgc tgctgcgccg
     9121 ccactccaac gaggagatcg ccgaggacct ccatctggcc cgccagacgg tgaagaacta
     9181 cgtcagcaac atcctgcaga agctgggcgt ctccagccgc cgcgaactgc tgaccggcaa
     9241 gatcccgacc cagcccgccg ccagggcacc gctgcccggc cgggcccggg acctggtggc
     9301 gacacgtagc gaaagagggg gcaaccggcc atgagaagcg tccggttcac cgaatacggc
     9361 gggcccgagg tgctcgccct ggacgaccgc gccgccgagc cggtccccgg cgaggacgag
     9421 gtgctcgtcg aggtcaccca cgccggcgtc accttcgccg atgtgatgtt ccggcgcggg
     9481 cagatcccgg tcggcctgcc cttcgcgccc ggtctggagg cggtgggcac cgtccgcgcc
     9541 accggctccg cggtcaccgg cgtccgcgcg ggccagcgcg tcgcggcgct ctgcctcggc
     9601 ggcggcgccc tgtccgaacg cgtcgtcgcc aaggccggtc tgaccgtccc cctcgagggc
     9661 gcgctcgccg gactcggctc cgcggccgcc gcgggcatga tcaccaacgg cgtcaccgcc
     9721 tggggcctgg tgcacgccgc tgcccggatc ggcgccgggg acaccgtcct cgtgctcgcc
     9781 gcggcgggcg gagtcggcac cgccgtcgcg cagttggcga aggcggccgg ggcccggctc
     9841 gtcatcgggg cggtcggcag cccggagaag gcggcccgcc tcaccgaccc cgcctacgac
     9901 gccgtgacca cctacgcctc gctcgccgcg gaggtcgaac ggcacaccgg ggagcggggc
     9961 gtggaccacg ccttcgactc ggtcggcggc gagccgcgca ccgcggtgga caagctgctc
    10021 gcgcccttcg gacggcacgt catctacggc gacgccgccc agcaggacac ccaatacccg
    10081 ggcaaccacg tctggttcac caactccgcc ctggtcggct acaacctcgg cgacgtggcc
    10141 ggccgcgacc ccgccctgct gcggagccac ctggagtccg ccctgcgcgc cctcgccgag
    10201 gggcggctgc gcggcgaacc ggccaccgcc gcccccgagg agatcgccaa ggtgcacacc
    10261 gagctggagt cccgcgccag caccggcaag tacgtcgtcg cctggtgacc cctgccgccc
    10321 accggccgcc cgctcccgcg gccggtgcgc ggcaggcccg cacatcttgt gccggatgag
    10381 cccgaagtcc cgctgtgcag gcgggacttc gggctcctgc cgtatgcggg ggggggtgta
    10441 ccggcccggt ccgccgggcg tccccgtcgg gcgggcctta ggcggctgcg gacggatgct
    10501 cccgaccgga tgccctcgga cgggtctgcc ggtcagggct gccgtacggg cctccccgta
    10561 cgggtcccgc acgacccgcg ccgccaccct cgctcctaag ccacccgcgc cgcccccgcg
    10621 aacggcatcc ggctgatcgg ggcgatgcgc accggggcgc cgggccgggg cgcgtggatc
    10681 atcttgccgc cgcccacgta gatgccgaca tggctgatgc ccgagtagaa gaacaccagg
    10741 tccccgggcc gcagttgacc ccgcccgatg cgggtgccgg cgttgatctg gctgtacgtg
    10801 gtccgcggca gcgagacccc ggccgcgcgg taggccgcct ggatcaggcc cgagcagtcg
    10861 aaggagttcg gcccggtggc gccccagaca tagggcttgc ccagggcgcg gtaggcgtag
    10921 gcgaccgcgg cgccggcccg ggagccgggg gccgccgcgg tcggtgcggg cgccgcggcc
    10981 ggggcggcgg tgcgcgcctg ctcgcgggag gcgcggccgt cctcccgggt ggccgcggca
    11041 cgttcctcgg cggtcagccg gtccagcaac tgccgtgccc ggcccagctt ctcctgcacc
    11101 gcgcgcttgc tgcgcgccag ctcgctctgc tgggtgccca gccggtccgc cacccggtcg
    11161 gcctcgccgc gcagccgggc cagcttgcgc agctgcccgc gcgcctcgcc gaccgcggcc
    11221 gcctggcggt gggaggcccg ctccgcgacg gccgtgccgc gcaggtactc ctccgggtcg
    11281 gcggacatca ccagttgcag cgccgggtcg agggtgccct cgcggtactg cgcggtggcg
    11341 agcgaggcga gcccggcgcg ggtggagccg aggcgctccg cggtgcgcgc cgcctcctcg
    11401 cgcagcccgc gcagcgaggt ccgcgccgcg tccgccttct ccttggcgcc gttgtacttc
    11461 tccgtcgcca cctcggcctg ccggtacagc cggtccacct gggcgcggac ctcgccgggg
    11521 cgcgcctcgg gcgccgcctg acccgtaccg ccgagggcgg tggcggccgt cgccccggtc
    11581 acggcgaggg tggccgccgc gcggccgggg gtgccgccga ggagacggcg gccgggtttt
    11641 cggtgcttcc tgtgctgcgc ggccacgagg gctccacgtc cttccctgac gtacggcggt
    11701 acctgcgccc ggggcccggc cgccgcccgc acggggggag cgggccgcgg ccggagcccg
    11761 ggcggggcgc ccggcggccg tcctcgcgga cggcggtgag aggccgggca cctggagaag
    11821 gacgctaggc cgcggacccc cgcgagaacc ttgatgtccc caactgcccg cagttgacag
    11881 cccgctgacc gcttacgacc gtctcggcgg cccggcgcgt ccgttgccgc gccgagctga
    11941 ccgaagtggg ggagcggctc ccggcggcgg tcggcggatg ctagggggtg gagagccccg
    12001 ccgcggcccc ggaaccggac tcccggcctc ccgcgacccg ccgccggtac cgcccggggc
    12061 ccccgttacg ctcccggcca tggacgtact catccacctc ttcgtcggcc tgcacatcat
    12121 cggcatcgcc agcctgctgg gcggcttcct gacccagatg aaggccctgg gcgagggcac
    12181 ggcacggttc agcccggcga tgctgcacgg cgccctgacg atgctggtga ccggggtgat
    12241 cctggtcggg ctcaaccagg ccgacgacaa caccgtcaac aacgtcaaga tcggcgtgaa
    12301 gctcgcgctg ctcgtggtga tcctcggcct ggtctacgtc aagcgggacg aggagcgcgc
    12361 ggacaaggcg cagttcgggc tcgtcggcgg gctgacggcg gcgaacgtct tcatcgcggt
    12421 gctgtggacc tgaggagctg aggagtcgag tcgcggtgcc atgaggccgg gcgtcgcggc
    12481 ggcgtgaggc cgggcgtcgc ggtgccgtgc gcctgaggcc cggcccggcg gaggccccgc
    12541 ccgcgcggcc cggcgggttg ccgagcggcc ccgctcagcc cggccgtacc acgctgtgga
    12601 tcggcatgta gtagatcgac tcctcgcgca catcggcccc cggtttcggg gcgtggacca
    12661 tcgtgccgtc gccgaggtag agcccgacgt ggctgatgtc gtcgtagaag aagacgagat
    12721 cgccggggcg ggcctcggag accgggatcg tggtgcccgt cttcacctgg tcccaggtgg
    12781 tgcgcggcag ggtgatcccg gccgccttcc aggccgcgag ggtcaggccc gagcagtcga
    12841 aggagtccgg accggtggcg ccccagacgt agggcttgcc gatctgctgc cgggcgaagg
    12901 cgagcgcctg ctcgccctgc gcggcggagg cgccgcccgg ggtgccgggg gtctcctcgc
    12961 cgccgccggt gccgccctcg tcgttctccc gctcctcccg ctcccggcgc tcgcgctcct
    13021 cggcctgctt gcgggcgagg gcggcggcct tgcggcgggc ctcctcttcc ttcttcttct
    13081 cgatcgccgc gagccgcgcc ttctccttcg cggtcagctg cgagagcagg gtgcgtgccg
    13141 tgccgagctt cgcctgcacg tcctgcttgg cgctcttcag gctccgctgg ctgccggtca
    13201 gcttcgccag gctcctggtc gcctcggccc gcttgcgcgc ggtggacagc tgctgcgact
    13261 ggtagtcgtc gacggccttc ttctgccgcc cggtcagccg gtgcatcagc tgggtctggt
    13321 cgaagtactg ggccgggtcg tccgcgagca gcagggtggc ggtgcccgag acaccgccgg
    13381 tgcggtactg ggcggcggcg aaggaaccga gttcggcgcg ggcctcgttc agcttctcgg
    13441 tgcgccgggc cacgtcgtcg aggaggccgt cgaccttgcg gcgctgggcg tccgcgcgct
    13501 ccttggccgc gttgtacttc tgggtggcca cgcccgcctc gtggtagagg ccgtcgacct
    13561 tcttacgtac ctcttccagg ctcggcctcg gtttctcggg cgcggcggtg gcgctctgcg
    13621 agagcagggc gaccgaggtg agcgcggcgg tggtcaggcc gacggcgggg ccgggcacca
    13681 cacgggggct gcgcggcttg cggtgcgacg ccaaggcggc gactccttcc gtgggccggc
    13741 cgcggagggc gtgccggacg ttgcgggcgc ccgggtccgg tgcggtctcg ccggtccgga
    13801 cgggctgccc gccgggcacg ctagccaact cgtggagcgg ctgtgaaggt tgatgcgcca
    13861 tgtgtccgat atgtttttgt gactttcgcg cggggtgaga tcacgtaagc ggagggtgcg
    13921 ttccgccccc tgggcggccg cgagcgggaa ccggcggcgg gctgtcagtg cggccgccta
    13981 gactcgggca acgatgagca gcctctttga cgacagcttc ctggcggacc tccgcgcccc
    14041 gcgcgaggaa gcgcccccgc cgcccgagga ccccgagggc gaggagcggg aagacctgcc
    14101 cgacgacctg ttcggaggga agtacgacgt gccgccaccc cgcgacgccc actaccgcga
    14161 cggcgccccg cgtcccgcgg tggactcggc cgccctcgtc gagggactga acgagcagca
    14221 gcgcgccgcc gtcgtgcaca gcggctcccc cctgctcatc gtcgccggcg cgggctccgg
    14281 caagacccgg gtgctcaccc accgcatcgc ctatctgctc gccgagcgcg gcgcgcaccc
    14341 gggccagatc ctcgcgatca ccttcaccaa caaggccgcg ggcgagatga aggagcgcgt
    14401 cgagcagctc gtcggaccgc gcgccaacgc catgtgggtc tccaccttcc acagcgcctg
    14461 cgtccgcatc ctgcgccgcg agtcgaagaa gctcggcttc acctcctcct tctcgatcta
    14521 cgacgccgcc gactccaagc gcctgatggc cctggtctgc cgcgatctgg acctcgaccc
    14581 gaagaagttc ccgccgaagt ccttcagcgc caaggtctcc ggactgaaga acgagctgat
    14641 cgacgaggag gacttcgccg caaaagcagc cgacggcttc gagaagaccc tcgcccaggc
    14701 ctacgcgatg taccagtcgc ggctgcgcga ggcgaacgcc ctcgacttcg acgacctgat
    14761 catgaccacg gtcaacctgc tgcgcgcctt cccggacgtc gccgagcact accgccgccg
    14821 cttccggcac gtcctggtcg acgagtacca ggacaccaac cacgcccagt acgccctcgt
    14881 acgcgagctg gtgggccgcg agcccgaccc ggaggcggag cccgcgccgg atgccgcgcc
    14941 gccgccgccc gccgagctgt gcgtggtggg cgacgcggac cagagcatct acgccttccg
    15001 cggcgccacc atccgcaaca tcctccagtt cgaggaggac tacccggacg ccaccaccat
    15061 cctcctggag cagaactacc gctccaccca gaccatcctc accgccgcca acgccgtcat
    15121 cgagcgcaac gagagccgcc gccccaagaa cctgtggacc aacgcgggcg cgggcgcgca
    15181 gatcaccggg tacgtctccg acaccgagca cgacgaggcg cagttcgtcg ccgaggagat
    15241 cgaccggctg accgacgcgg gcgaggccaa ggcgggggac gtcgcggtct tctaccgcac
    15301 caacgcccag tcccgcgtct tcgaggaggt cttcatccgc gtaggcctcc cgtacaaggt
    15361 cgtcggcggt gtccgcttct acgagcgcaa ggaggtccgg gacgtcctcg cctacctgcg
    15421 cgtgctcgcc aaccccgagg actccgtccc gctgcgccgc atcctcaacg tccccaagcg
    15481 cggcatcggc gaccgcgccg aggcgatgat cgacgcgctc tcccagcgcg agaagatcag
    15541 cttccccgcg gccctgcgcc gggtcgacga ggcgtacggc atggccgcgc gctccgccaa
    15601 cgccgtcaag cgcttcaaca cgctgatgga ggacctgcgc accgtcgtcg agtccggcgc
    15661 gggcccggcg accgtcctgg aggccgtcct cgaacgcacc ggctacctcg cggagctcca
    15721 gtcctccacc gacccgcagg acgagacccg tatcgagaac ctccaggaac tcgccgcggt
    15781 ggccctggag ttcgagcagg agaccggcga gggcgaggag agcgccaccc tctccgactt
    15841 cctggagcgg gtcgccctgg tcgccgactc cgaccagatc cccgacgagg aggacggcaa
    15901 cggcgtcatc accctgatga ccctgcacac cgccaagggc ctcgaattcc cggtggtctt
    15961 cctgaccggc atggaggacg gcgtcttccc gcacatgcgc gccctcggcc agaccaagga
    16021 gctggaggag gagcgccggc tcgcctacgt cggcatcacc cgcgcccgcg aacgcctcta
    16081 cctcacccgc tccaccctgc gcagcgcctg gggccagccc tcgtacaacc cgccctcccg
    16141 cttcctggag gagatccccg ccgcccacct ggagtggaag cgcaccggcg cccccgcccc
    16201 ggtctcctcg ggcccggcct ccggcgtcgc cgcctccctc tcctcctcgc gcgcacgcgg
    16261 gggtgcgggc ggcgcctccg gcttcgccac ccgccgggcc ggggagaagc cggtcgtctc
    16321 cctcgcggtc ggcgaccggg tcacccacga ccagttcggc ctcggcaccg tcgtcggcgt
    16381 caagggcacc ggcggcaacg ccgaggccac cgtcgacttc ggggacccca agccgaagcg
    16441 cctgctgctg cggtacgcac cggtggagaa gctctgaccc ctcgcccggc gccctgaagc
    16501 accgccgacc tccccgtccg attcccgcca gccggccggt tcctgccgca gcacactggc
    16561 cgcatgacca cctacacccc gctccccatc ccgcccgccg cgctcgcgga gctccgcggc
    16621 accgacgact ccgggcgccc gatgcgcccg tacaccgccc gcgaggacgg tgtcccgctc
    16681 gactgcgtgg gcagcccgct gcgctgctgc ctgcgccccg tcgaggcggg cgagcgggtc
    16741 gccctggtct cctacgcgcc gctgcgccgc tgggcccgta cgaccggtgc cacgcccggg
    16801 gcctacgacg aggccgggcc ggtcttcctg cacgccgagg agtgcccggg gccgcgcggg
    16861 gagggctatc ccttcgcgcg ccccggcgcg ctgcgcaccc tgcgccgcta cgacagcgcg
    16921 gggcacatcg tcgggggacg cctcttcgag atcccgcagg aggccgggcc cggcttcgac
    16981 aaggcgctcg gggaggcctt cgccgatccg cgggtggccc tggtgcacgt acgcgccgtc
    17041 gagtacggct gcttccagtt cgaggtacgg cggccgtag
//
