LOCUS       reptomyces_RBGC_682298 15883 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_682298
VERSION     Streptomyces_RBGC_682298
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000720135.1
  ORGANISM  GCF_000720135.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..1782)
                     /protein_domains="PF00664"
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3227650"
                     /pseudo=False
                     /translation="MTRTHDTPENDKALVAGRATALRAACDLIRQDRMAFVAMLLFNAL
                     AVGAGLVGPWVIGEIINRVQKGTTAETVDRLALLLTVTAVVQFLLVRLARYVGFRFGER
                     TLARVREQFVDHVLALPLSTVEEAGTGDLAVRGTTDVNTVGMALRDAGPDVFVAAVQVP
                     LILGAVFLVSPLLGVCGVVGLAGIGVAVRWYLRRAHTAYLAEGEANSALAEQLAAAAAG
                     ARTIEAFRLEDRHIAQSLEAIETCYRTRTRTLHLRSVLFPAVDISYVIPVASVLLVGGV
                     LHNHGLVSIGALVASALYFRQLSQPLDTLLQWLELLQSSGASFARVEGVRPAPGANEPA
                     GTEGGVGQPTGHGIELDHVHFSYDGVTDVVQDVSLTIRPGERLVVVGPSGAGKTTLSRL
                     IAGTDKPHRGSVLVGGVPVAALPPETLRRQMVLVTQEHHVFIGTVRDNLSIAAPTATDE
                     EFMGALSAVGADWAERLPRGLDTRLGTQRNRLNGAQAQQLGLARVLLANPHTLILDEAT
                     ALLDPRTARRAERTLATVLEGRTVIAVAHRLHTAHDADRVAVLEGGRLTELGSHDDLVS
                     AGGTYAGLWRSWHGSPT*"
     CDS             complement(1780..3524)
                     /protein_domains="PF00664"
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3227651"
                     /pseudo=False
                     /translation="MTPDIRGPLRYIWWLITSQRVRVLGGALLGSCWMVGLMLPPYLLS
                     RAIDDGLTAGDSTALLGWTGALVGVGVLNAWLAIMRHRTMTRVRMDAAFRSVRLVSEQV
                     TRLGAVLPRRLSSGEVFAIGFGDVARVANVLTITGPGLGAVLAYVVVAVLMLVISPLLA
                     LLVLLGVPVLAVVVGPLMGRLQGAESTYREHAGRLAARLVDMIEGLRVLNGIGGKAVHA
                     ERFHRHSQTLRAEGYRVGAVTSWIQALGVGLPAVFLAAVTWVSARMAADNTITPGELVS
                     VYGYAAVLVVPVSFFIEGAYDLSHGVVAGRRLIRFLALSPHSADPAAGLDGPEGPAALH
                     DPESGVTVAPGEFTALVSARSEDSAAIVDRLGCFTESKATWGDVPLDRIALLQVRERIL
                     VADNEAALFRDSLLGVISGRAERDPQAVQRAVEAAVAQDIVRGLPDGLESVIQANGRNL
                     SGGQRQRVRLARALLAEPETLMAVEPTSAVDAHTEAAIAERLYAHRKGRTTVVTTTSPL
                     LLARADRICYVVDGKTVGTGTHRHLLASHPGYRRLVSRELGDLQDDAQDFRAEPSPETK
                     EGTAR*"
     CDS             complement(3791..5100)
                     /protein_domains="PF00668"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3227652"
                     /pseudo=False
                     /translation="VNAERTGPVTFGQLSVLRSLESYGSVGQRVANLVSVWPVPAGASV
                     GHVVDAWQQLVVAHESLRTGFSTERGRPVQTVHPAGVVSVPVLEVSEDAHAATRELAAE
                     WAADPIDITAGQPWRAFAVVHRGAPLYLVAVIHHIAADNGALRVLREQFQRLVEGEVLG
                     PQAQPLDLALAQQEDAHAARAVDHWAVRWGPFRPEDRQEGDTSTRRRATLYSVEGLQAA
                     RRIAQRSGASVQAIVLALGALALARVKERDQITFGLMTANRLDRQWSELVSSLNQCVPF
                     TVDIDDESAPDSFLNTTYRASMDAYLHGCFDVDALRSELTARGRLETDPTYFSAHYNFL
                     GAGDGEPPQDAPVRTGVAWRTSHQRIGPNFHLAVAIERGLFIGVGASVDYLPDELPAFL
                     AASIEGGLMTLADSPPESLGKLSLEPRRDLGRQPRQS*"
     CDS             complement(5231..6366)
                     /protein_domains="PF00441"
                     /protein_domains="PF02771"
                     /protein_domains="PF02770"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3227653"
                     /pseudo=False
                     /translation="MLHHLSPEQQDSRRAFRAFAERVLMPHAARFDAEELLSRDSILSL
                     AEHGYIGSMISPEFKGRDFSPVQYGLLSEELGRACQSIRNFVAVQDMVAHSIEMWGTSA
                     QKERWLPGILSGETVAAFALTEPDFGSDAAAVRTTATSAGADFLLTGTKKWISFAQTAR
                     LFLVFAQLAGEHTAFLVERDDHRLQVEPIKGLLGLRGSMLGSIRFDECRVPAESMVGGP
                     GFGLAWVAANALDLGRYSTAWGSVGLAQACLEACSGYADARRQYGTQIKNHQLVQQLLA
                     DMVTDTMAARLLCHHAGVSKEKSDVDAVHHTLMAKYRASTVAVRVASDAVQIHGAQGIG
                     ADSPAQRHYRDAKVLEIIEGTTQIQQTLIGGFASSAAR*"
     CDS             complement(6405..6994)
                     /protein_domains="PF00291"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3227654"
                     /pseudo=False
                     /translation="VARKFAAEREIVWEGGFFNWARREGLKIAYLEAFDEMKEQPDVVV
                     QAISSGMGVMAARKGAEEYLATGRIGSVPRFLMVQQDTCAPMADAWRSGREELTDEDVI
                     ERPNGLARAILLGDGRDSYPYMRDIAHATGGGIVSVSQTEMTEAREMLRELEGLDVCHS
                     AAATIAALRNEVQADRIGADEVVLANLTGRTRH*"
     CDS             7470..7624
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MPELRLTSPATSNAFEIKSHVASPSAPLTIITVQSTQKYQCGAIR
                     TSGPSV"
     CDS             7935..11203
                     /protein_domains="PF00501"
                     /protein_domains="PF00668"
                     /protein_domains="PF00550"
                     /protein_domains="PF13193"
                     /protein_domains="TIGR01733"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3227655"
                     /pseudo=False
                     /translation="MTFSRPGRTDSAQTGPAQPGDVLSPAQQRIWALGHLAPDTSLLHV
                     PVVARLTGELDHGRLEAALHDAVARHPVLATRFTVADRRLIGRSVTDRGPAGLSFEWHR
                     LEARDDAADVTRRMDVWTRRVINAPFSLEEGPLVRGCLISGSAREHLLVLVFHRLIADT
                     TSAGIVFREALALHASLRHEPDPGERDPWAPRLSPADERGEEASWSPHPAPVALRPQLP
                     YDRPRPTTRDLRVDSVPFTLPPVATAGLRDLARGCGGGPASVTLALFVLLLHRYSGQTD
                     PVVTVTTPGRSAQQTATVGCFESALPIGFSVDTDMTFRQLVRLVHQRAVSAVLGAAAES
                     ETAPDSPAPGRAGPATVWPAFSHRALPPVPASSGLTSEVLPAHSDCALEDLGLHLWDDG
                     QRLRGQLVFATGLFDSVSAHRTVGHLLRLTDAVLSDPDRPVGSLAFLTAEEVNTVAVLN
                     SVVVDVPETTFSQVFEQQAERSPHAVAIRAEDTCLSYGELNTRANQLAHLLRERGVGPE
                     VTVGLVLERSAQLAVAVLAVLKAGGTYVPVDPDDPPARRDTILEDASVRIVVAHKDKQP
                     VRRHDGPRVIEIDSSWSAFDALPPGNPRGDHRHPSHAAYLLYTSGSTGRPKGVVIEHRQ
                     LMNYVYGVIERFDIREPLSFAMVQPLTVDSSVTALVPPLCTGGEVHMITRERALDATGL
                     ADWFERWPVDCLKIAPSHLRALQLSPRFTSVLPRRLLVVGGEASDWRWLRELQQMAPQC
                     QVFNHYGPTETTVGVLTLAVADHVDAKWTTAPIGVPLPNTQAYVVDEAGQPVPVGVAGE
                     LLIGGDSLARGYHGRDDLTHEAFIPDHLGHRPGARLYRTGDIVRRLPSGIVEFIGRRDD
                     QIKVRGFRVALGEIDAALMSCPEVRHAVTVVREDTPGDRRIVSYVEPERFEEFRPDAVH
                     QHIRGRLPSHMMPRALVPLPRLPLSDHGKVDRRALPPPVPEPSPPAGALAPGNDTERRV
                     AQVWMRVLDVADVGLEQNFFDLGGHSLLLVELQHRLQRALGKEIDLLDLFQHTTVRAQA
                     DFFSRQEPPVAHEDGTAGTRQQRALLKRRQQQLRTKRGRRE*"
     CDS             11197..15776
                     /protein_domains="PF00109"
                     /protein_domains="PF00698"
                     /protein_domains="PF08659"
                     /protein_domains="PF02801"
                     /protein_domains="PF16197"
                     /protein_domains="PF00550"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3227656"
                     /pseudo=False
                     /translation="VSNDLTETTVDASEDSLDIAVVGMAGRFPGADSLEEFWDNLRSGK
                     CSVTSFDEAQLAERGVDAATLGNPDFVPYGYVLEDARQFDAAFFGYSAREAELMDPQHR
                     VLLECAWAAMESSGHDPERYDGSIGVFAGAGNNTYLLRNIATQPDAAELCADKQVVIGN
                     RSDFLSSRVSYKLGLRGPSVNVQSACSTSLVAVVEACQSLLAYQCDMALAGGVAIDDSR
                     RDGYIHRPDGILSPDGYCRTFDARAQGTVGGDGVGMVVLKRLGDAIADGDHIHAVIKGG
                     AVNNDGAERAGFTAPNPVAQAEAIAAALSDADVAAESIRYVELHGTATILGDPIEFKAL
                     TSAFQGVGPGNCAVGSVKTNIGHLDSAAGVAGLIKTVLAVEHGQIPPSLHFHTPNPRLG
                     LEGSPFYVNTELLDWPEHEGPRRAGVSSFGLGGTNAHVVLEEAPPPRSALRPCDEGAEQ
                     LLVWSAKSMEALEAATDRLADHLRTHPDQNLADVAFTLRAGRKSLPFRRMLVCRSGDEA
                     LEAIDARDDGRLLTTAAPDVSGRPVGFLCAGFGSQFPGMARALYSREAVFREVLDRCAT
                     HLHALLGQDIRPLLLTGSDAPDAEAGTAVPDFRSFLLQPARSDHTLDLPSIGYPAVFAL
                     EYALAELWQEWGVEPVAMIGHSLGEYVAACLAGVFDLPDALRLVVERARLIEKQGEGAM
                     LAVPLSEEEAARYTDDEVCLAAVNGPRTCVLSGTITGIERASRELQAAGLASRLLTSRF
                     AFHSPMMDPVVEPYRDVVRSVRLNPPSKPFVSNLTGTWITDQEATSPDYWAQHLRGTVR
                     FADGIATLWSVPDIVLVEIGPAPVHTADVLQHPAAGQVPDRVVVASTPRPLAGRSNRAT
                     LLDAAGRLWLAGHRQVFPSAPGSRRVPLPTYPFERRTYWLAPGTPRLHETSAEQRAGSL
                     PQWFYAQSWQRAAAAPPPDMADLGARRWLVFVDGMGVGRRLAHRLEELGASVVRAVAGT
                     EWSDSGDREYVLHPGQPAHFAMLAAALRADGGLPDRIVHCWSVGDDARGAAEPEAAEAL
                     LDRAFGSLIHWAQATDTELMTSHQRWDVVSSEVYSVIGDEELCPPKAVVQGVCRVLPQE
                     YPSVDCAHLDLRTGEGEEPDTLAGRLLAELARPAAERTLALRGRHRWKPDFARVSPPSR
                     GTSPVRPDGVYLITGGLGKIGLLVGRALAERCRVRLVLLGRTGLPPRASWDDSQHPAAV
                     REVIRAIRALEDLGSEVMVRAADVADASAMVRVKDEIVQRFGCLSGVVHCAGSTGSAAH
                     RSITDLGPEESSWHFAPKVHGMRVLHEILADQKLDFAVICSSVASLLGGLGFAAYAAAN
                     AALDAFAQRHHSPQLPWTSVNWEAWLFSDEGRGSARIGAAVKDLALTPQEGRQVWDVLL
                     DAVPEPQVVVSTGDMSRRHALWSAPVAGEPAVRRYARPDLSNPFVAPAGASEHRIAEIW
                     QELMGVDRVGAHDNFFELGGSSLLGLQVVHRLRRDLGVAVPLTIVYEGPTVRTLGALVD
                     QVREDR*"
     CDS             15777..15883
                     /protein_domains="PF00109"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3227657"
                     /pseudo=False
                     /translation="MDRRGGVAIIGMAGRFPGARDLTEFWENLRDGVESI"
ORIGIN
        1 tcatgtcggg cttccgtgcc aggaacgcca caggccggcg taggtcccgc ccgcggagac
       61 cagatcgtca tgactgccca gctcggtgag ccgtccgccc tcgaggacgg ccacccggtc
      121 ggcgtcatgg gcggtgtgga gacggtgtgc cacggcgatg accgtccgtc cctccagcac
      181 ggtggcgagg gtgcgctcgg cacggcgcgc cgttcgcggg tcgagcagag ctgtcgcttc
      241 gtcgaggatc aaggtgtggg ggttggcgag cagcacccgt gccagtccta gttgctgtgc
      301 ctgcgccccg ttcaggcggt tgcgttgggt gccgagtcgt gtgtccagtc cgcggggcag
      361 gcgctcggcc cagtccgcgc cgacggctga caacgccccc atgaattcct cgtccgtggc
      421 cgtgggcgcc gcgatggaga gattatcgcg cacggtaccg atgaagacgt ggtgctcctg
      481 ggtgaccagg accatctgac ggcgcagtgt ctccggcggc aatgcggcga cggggactcc
      541 gccgacgagc acggaccccc ggtgcggttt gtcggtgccg gcgatcagtc tgctcagcgt
      601 ggtcttgccc gccccggacg gccccaccac caccagccgt tcacccgggc gtatggtcag
      661 ggacacgtcc tgcaccacgt cggtgacgcc gtcgtaggag aagtgcacat ggtccagctc
      721 gatgccgtga ccggtcggct gcccgacgcc gccctcggta ccggctggct cgtttgcgcc
      781 gggcgccgga cgaaccccct ccaccctggc gaacgacgcc ccgctgctct gcagcagctc
      841 cagccattgc agcagcgtgt ccagcggctg cgacagctgc cggaagtaca gcgccgaggc
      901 aaccagtgct ccgatgctga ccagcccgtg gttgtgtagc acgccgccca ccaagaggac
      961 actggcgaca gggatgacgt acgagatgtc gacggccgga aagaggacac tgcgcaggtg
     1021 cagggtgcgg gtgcgggtcc ggtaacaggt ctcgatagct tcgaggctct gcgcgatgtg
     1081 acggtcctcc agccggaacg cctcgatcgt gcgggcgccg gccgcagccg cggcgagctg
     1141 ctcggcaagc gctgaattcg cctccccctc ggccaggtag gccgtatgcg cccggcgcag
     1201 gtaccagcgg acggccacgc cgattccggc gagcccgact acaccgcaca ctccgagcag
     1261 agggctgacc aggaagaccg ctccgaggat gagcggcacc tggacggcgg cgacgaacac
     1321 gtccggcccg gcgtcccgca gcgccatgcc caccgtgttg acatcggtgg taccgcgaac
     1381 cgccaggtca cccgtgcccg cctcctcgac ggtggacagg ggaagcgcca ggacgtgatc
     1441 cacgaactgc tcacgcacgc gggccagagt ccgttcgccg aagcggaagc cgacatacct
     1501 ggccaggcgg acgagcagga actggaccac cgcggtgacg gtcagcagca aggccagccg
     1561 gtccacggtc tcggccgtcg tgcccttctg cacgcggttg atgatctccc cgatcaccca
     1621 tggccccacc agtcccgccc cgacggcaag cgcgttgaac agcagcatgg cgacgaaggc
     1681 catccggtcc tgccgaatga ggtcgcaggc tgcccgcagc gccgtggcgc gtccggcgac
     1741 cagggccttg tcattctccg gggtgtcgtg ggtacgggtc atcgggccgt cccctccttc
     1801 gtctcggggg acggctccgc ccggaagtcc tgcgcatcgt cctgcaggtc acccagctcc
     1861 cgggagacaa gccgccggta cccgggatgg ctggccagga gatgccggtg cgtacccgtg
     1921 ccgaccgtct tgccgtcgac gacgtagcaa atcctgtcag ccctggcgag cagcaggggc
     1981 gacgtcgtgg tgaccactgt cgtacggccc ttccggtggg cgtagagccg ttccgcgatg
     2041 gctgcttcgg tgtgcgcatc caccgccgac gtcggctcca cggccatcag cgtctccggt
     2101 tcggccagga gcgcccgcgc gagacgcact cgctgccgct ggccaccgga cagattgcgg
     2161 ccgttggcct ggatgacgga ttccagcccg tcgggcaggc cccgcacgat gtcttgtgcg
     2221 acggcggcct cgacagcccg ttgcacggcc tgggggtccc gctccgcccg gccgctgatg
     2281 acgcccagca aagagtcgcg gaacaaggcg gcctcgttgt cggccaccag gatgcgttcg
     2341 cggacctgga gcagggcgat ccggtccagt gggacatcac cccaggtggc cttcgactcc
     2401 gtgaagcagc caaggcggtc gacaatggct gcggagtcct cggagcgggc gcttaccagg
     2461 gcggtgaact ccccgggggc caccgtgacg cccgattccg ggtcgtgcag cgcggcaggt
     2521 ccctcggggc cgtccagacc cgcggcgggg tcggcggagt gcggtgagag cgcgaggaac
     2581 cggatgagac gacgacctgc caccacaccg tgactcaggt cgtaggcacc ctcgatgaaa
     2641 aaggacaccg ggaccacgag gacggccgcg tagccgtaga ccgacacaag ttcgcccggc
     2701 gttatcgtgt tgtcggcggc cattcgcgcc gacacccatg tgaccgcggc gaggaacacg
     2761 gccggcagcc ccacaccgag tgcctggatc caactggtca cggccccgac gcggtacccc
     2821 tctgctcgca gtgtctggga gtgacgatgg aagcgctcgg cgtggaccgc cttgccgcca
     2881 atgccgttga ggacccgcag gccctcgatc atgtcgacca atcgggcggc gagacgcccg
     2941 gcatgttccc gatacgtcga ctccgcgccc tgcagacgcc ccatcagcgg acccacgacc
     3001 accgccagca ccgggacgcc gagcaggacg agcaaggcca gcaagggcga gatgacgagc
     3061 atcaggacag ccacgaccac gtaggcgagg acggcgccca ggcccggccc cgtgatggtc
     3121 aggacgttgg cgacccgagc cacgtcgccg aagccgatcg cgaagacctc tcccgacgac
     3181 aggcgccgcg ggagcacggc tcccagacgg gtcacctgct cggacaccag ccgcaccgac
     3241 cggaacgccg cgtccatgcg gaccctcgtc atggtgcggt gccgcatgat ggccagccat
     3301 gcgttcagca cgcccacgcc caccagtgcg ccggtccagc cgaggagtgc cgtgctgtca
     3361 cccgcggtca acccgtcgtc gatcgccctc gacagcaggt aaggcgggag catgaggccc
     3421 accatccagc aactgcccaa cagcgcgccg cccagcactc tgacgcgctg actggtgatc
     3481 aaccaccaga tgtagcgcag cggtccccgt atgtcgggtg tcatggaatg cgctgccgga
     3541 tcggctatcg cacggaaacc gactggagac ggggagcgca tcgcctcggc cggcgctgtc
     3601 ttcggcaacg ttcctcttcc tctggcgatc gatcggtcga ataatgttcc gggctccgac
     3661 ccctcggagc gatggcttgg cgtacgacga gaaggaaggg gacagccggg atgaagcgga
     3721 acaggcgctg tgtgtgctgc gacttctgac accccgtacg acggtctggt cctgaccccg
     3781 ctgccggggt caggactgtc ggggctgtct tcccaggtcg cggcggggtt cgaggctcag
     3841 cttccccagc gactccgggg ggctgtccgc gagggtcatc agcccgccct cgatggaggc
     3901 tgcgaggaac gcggggagtt cgtccgggag gtagtccacg ctggctccca ccccgatgaa
     3961 gagtccccgc tcgatcgcga ccgccaggtg gaagttcggc ccgatgcgct ggtgggaggt
     4021 gcgccaggca actcccgtac gcacgggtgc gtcctgcggc ggctcgccgt cgcccgcgcc
     4081 gaggaagttg tagtgggcgg agaagtaggt gggatccgtc tcgagccggc cgcgcgcggt
     4141 cagttcgctc cgtagcgcat cgacgtcgaa gcaaccgtgc aggtaggcat ccatactcgc
     4201 ccggtaggtg gtgttcagga acgagtccgg tgccgactcg tcgtcgatgt ccacggtgaa
     4261 cgggacacac tggttgagcg aactcaccag ctccgaccac tgccggtcga ggcggttcgc
     4321 tgtcatgagt ccgaacgtga tctggtcacg ctctttgacc cgcgccaggg cgagggcccc
     4381 gagtgcgagg acgatcgcct gcacggaggc gccggagcgt tgggcgatgc gccgtgcggc
     4441 ctgaagccct tccacgctgt agagggtggc gcgccgacgc gtgctcgtat cgccctcctg
     4501 gcggtcctcc ggccggaacg gcccccaccg cacggcccag tggtcgaccg cgcgcgcggc
     4561 gtgcgcgtct tcctgctggg cgagtgccag gtccagcggc tgcgcctggg gaccgaggac
     4621 ctcaccctcg acaagacgct ggaactgctc ccggagaaca cgcagggcgc cgttgtccgc
     4681 cgcgatgtga tggatgacgg cgaccaggta caacggcgct ccccggtgta ccacggcgaa
     4741 ggcacgccac ggctgccccg ccgtgatgtc gatcggatcc gcagcccact cggcagccag
     4801 ttccctcgtg gccgcgtgcg cgtcttcgga cacctcgagg acggggacgg aaaccactcc
     4861 tgccggatga accgtctgga ccggtctccc tctttccgtg gagaaaccgg tgcgcagcga
     4921 ttcgtgcgcg acgacgagtt gctgccaggc atcgaccaca tgtcccacgc tcgcgccggc
     4981 gggcaccggc caaacgctca ccagattcgc cacgcgttga ccgacggacc cataggattc
     5041 cagggaacgc agcactgata attgcccgaa agtgaccggt ccggtccgct cggcgttcac
     5101 cgtttttccc cctccttcgc gtgtcccacg cggagaccga cgaccaactt accgcctgac
     5161 cagtcgaaag gacaggcatc cagcgaacct cgggcgcaca caactcgttg ccgcttgaat
     5221 tagccgtcgt caccgagccg ccgacgaggc gaacccgcct atcagcgtct gctggatctg
     5281 cgtcgttcct tcgatgattt ccagaacctt tgcatcacgg taatgccgct gcgccgggga
     5341 atcagcaccg atgccctggg cgccatggat ctgtaccgcg tccgaggcaa cccgcaccgc
     5401 caccgtcgac gcgcggtact tcgccatgag cgtatggtgc acggcgtcta cgtcggactt
     5461 ctctttgctc actcccgcgt gatggcacag cagccgagcc gccatcgtgt cggtgaccat
     5521 gtccgcaagc agttgctgca ccaactggtg gttcttgatc tgcgtgccgt actgccgacg
     5581 cgcgtcggcg tatccggaac aggcttcgag acatgcctgc gccaggccga cggagcccca
     5641 tgcggtgctg taacgcccca gatcaagtgc gttcgcagca acccacgcga ggccgaatcc
     5701 gggcccaccc accatgctct cggcgggaac acggcactcg tcgaagcgaa tgctccccag
     5761 catcgagccc cgcaagccca gtagaccctt tatgggctcc acctggagtc tgtggtcgtc
     5821 ccgttccacc aggaaggctg tgtgttcgcc ggcaagctgg gcgaacacca ggaagaggcg
     5881 ggctgtctgc gcgaaactga tccatttctt ggtgcccgtg agcaagaagt ccgcaccggc
     5941 cgaagtggca gtcgtccgca ccgcggcagc atcgctgccg aagtccggtt cagtgagcgc
     6001 gaaggctgcg acggtctcgc ccgacagaat gccgggaagc caccgctcct tctgcgcgga
     6061 agtgccccac atctcgatcg aatgggcgac catgtcctgc acagccacga agttacgtat
     6121 cgactgacag gctcttccca gttcctccga aagcagcccg tactgcaccg gtgaaaagtc
     6181 tcggcctttg aattccggcg aaatcatgga gccgatgtaa ccgtgttcgg ccagcgagag
     6241 gatactgtcg cgtgaaagga gctcctcggc gtcgaagcga gcggcgtggg gcatgagcac
     6301 gcgctctgcg aacgcacgga acgcgcggcg gctgtcctgc tgttccgggc tgagatgatg
     6361 cagcatcaag agacaccccc aagagatgcg gacgatcggg tggtcagtgc cgggttcggc
     6421 cggtgaggtt cgccagtacg acttcgtctg cgccgatacg atccgcttgt acttcgttgc
     6481 gcagggcggc gatggtggcg gcagcggagt ggcacacgtc aaggccctcg agttcacgaa
     6541 gcatttcccg cgcttccgtc atctctgtct ggctcaccga cacaatgccg ccgcccgtcg
     6601 catgagcgat gtcgcgcata taagggtagc tgtccctgcc gtcgccgaga agaattgcgc
     6661 gagccaggcc gttcggtcgc tctatgacgt cctcgtccgt cagttcctcg cggccggacc
     6721 gccaagcgtc cgccatcggc gcacacgtgt cctgctgcac catcaggaaa cgcggcaccg
     6781 acccgattcg ccctgtcgcg agatactctt ccgctccttt acgcgcggcc atgactccca
     6841 tgccgctact gatagcctgc acgacgacgt caggttgttc cttcatctcg tcgaaggctt
     6901 ccaaataggc aatcttgagc ccctccctgc gcgcccagtt gaaaaatccc ccctcccaga
     6961 cgatctctcg ctcggcggcg aatttccgcg ccacgcggct ggcatccgca taaccacccc
     7021 tcaccacatg gagtgatata cgatcgtccg tctcgagctg gtgatcggca acaaagtcct
     7081 cgctgcagaa gaagtgtgcc cgcatcgtcg ggtcccgtcg cacggcggcg gcgagtgccg
     7141 tagcggtgtt accagtgctc gacgtgaccc attccttgat accgaactgc cggaatacgg
     7201 caaggaccac cgaggcgagc cgatccttcg tagttccggt gggctgacgc gattcgtcct
     7261 tcagccacaa gtggcgtaat ccgagtttcg cccccagcgc aggcgccggc cggcaaggac
     7321 tgcgcacgct tgtcaccgga tcaatgaaat cgggggacat gaccggaaga aaatcgaagt
     7381 aagcatgttc cggctgatcg agatcccgcc ggaccgcatt ccgcagatca aacctgcact
     7441 ccagcactgc ggagcattcg ggacatcgat gcctgaactc cggctcacat cgccagcgac
     7501 atccaatgca ttcgagataa aatcgcacgt cgcctcgcca tccgccccgt taacaataat
     7561 aaccgttcaa tccacccaga agtatcaatg cggtgctatt cggacatctg ggccgtccgt
     7621 gtgaatccag ccagcgccgg tctgcggcca gtcattgctg cgtagcggcc agtctggcat
     7681 gatcagtctt gcagaaaaag accttctgtg tgcaggatgc agaggaagat aggggaaccg
     7741 gcaggggggc cgtgtcatga cggacagatc tcgacgtatt ccccttgcca tgtggaacct
     7801 gcagctgtcg ccaagcctta aaaggtgacc tcgccgattt gcacaccggc ccggttcttc
     7861 ttgttccgtg acggaacaca gtgtgcgcca cgactgattc tgctcttaag tgattccctc
     7921 gcaagggagc tccatgacgt tctcccgtcc aggacggact gattccgcgc aaacgggtcc
     7981 agctcagccg ggcgacgtgt tatcgccggc tcagcagcgc atctgggcgc tcggacacct
     8041 ggcgccggac acctctttgc tgcacgtgcc agtggtagcg cggctgaccg gcgaactgga
     8101 tcacggacga ctcgaggccg ccctgcacga tgccgtggcg cgtcatccgg tactcgccac
     8161 aaggttcacg gtcgctgacc ggcgcctcat cggcaggtcg gtcacggacc gtggccccgc
     8221 ggggctgtca ttcgagtggc accgcctgga ggcacgggac gacgcggccg acgtgacgcg
     8281 ccgtatggac gtgtggacga gacgcgtcat caacgcgccc ttctcccttg aagagggccc
     8341 cctggtccgg ggctgtctga tctccgggtc cgcccgggag cacctattgg tgctggtctt
     8401 ccaccggctg atcgccgaca cgacctcggc cggaatcgtt ttccgggagg cactggccct
     8461 gcacgccagc ctgcggcacg agcccgaccc gggtgagcgg gacccatggg ctccccggtt
     8521 gtcgccggcc gacgagcgcg gcgaagaggc gtcctggtcg ccgcaccccg caccggtggc
     8581 gctccggccg cagctgccgt atgaccggcc gcgtcccacc acacgggatc tgcgcgtgga
     8641 ctcggtgccc ttcacgctgc cccccgtcgc cacagcgggc ctgcgcgacc tggcgcgggg
     8701 atgcggtggc gggccggcct ccgtgacgct ggctctcttc gtgctgctcc tccaccgcta
     8761 cagcgggcag acggacccgg tggtgacggt gaccacaccg gggcggtccg cgcagcagac
     8821 agcgacggtg gggtgcttcg agagcgctct gcccatcggc ttctcagtgg acaccgacat
     8881 gaccttccgt cagctggtcc gcttggtgca ccagcgtgcc gtctccgccg tcctcggggc
     8941 cgccgcggag tccgagacag cccccgactc ccccgcgccg ggccgggccg ggcccgccac
     9001 cgtctggccg gccttctccc acagggccct gccgcctgta ccggcctcgt cggggctgac
     9061 gagtgaggtg ctgcccgccc acagcgactg cgcccttgag gatctcggcc tccacctgtg
     9121 ggacgacggt cagcggttgc gtggtcaact ggtcttcgcg accggcctct tcgacagcgt
     9181 ctccgcccac cggacggttg gccatctgct tcgcctcacg gacgcggtac tcagcgaccc
     9241 cgaccggccg gtgggttcct tggccttcct gaccgcggag gaggtgaaca cggtcgccgt
     9301 actgaacagc gtcgtggtcg atgtgccgga gacgaccttc tcgcaggtct tcgagcagca
     9361 ggcggaacgc tcgccccacg cggtggcgat ccgcgccgaa gacacctgtc tcagctacgg
     9421 cgaactcaac acacgggcca accaactggc ccatttgctg cgggagcggg gcgtcggccc
     9481 cgaggtgacc gtggggctcg tcctggaacg aagtgcccag ctggccgtgg cggtactcgc
     9541 ggtgctgaag gccggcggca cctatgtacc ggtcgacccg gacgaccccc cggcgcgcag
     9601 ggacaccatc ctggaggatg cctcggtccg gatcgtggtc gcccacaagg acaaacagcc
     9661 cgtccgccga cacgacggac cacgggtgat cgagatcgac agttcatgga gcgcgttcga
     9721 tgcccttccc ccgggaaatc cccggggcga tcaccggcac ccctcccacg ccgcctacct
     9781 gttgtacacc tcggggtcta ccgggcgtcc caagggggtg gtgatcgagc accggcagct
     9841 catgaactac gtctacggcg tcatcgagcg gttcgatatc agggaaccgc tgagtttcgc
     9901 gatggtgcag cccctgaccg tcgactccag cgtcaccgcc ctggtgccgc cgctgtgcac
     9961 gggcggagaa gttcacatga tcactcggga gcgcgcgctg gacgcgaccg gactggccga
    10021 ctggttcgag cgctggccgg tcgactgtct gaagatcgct ccgtcgcacc tccgagcctt
    10081 gcagctctcc ccccggttca cctccgtact gccacggcga ctcctggtcg tcggcggcga
    10141 ggcatcggac tggaggtggc tccgcgagct ccagcagatg gcgccccagt gccaggtctt
    10201 caatcactac gggccgacgg aaacgaccgt cggagtgctg acgctggcgg tggccgacca
    10261 tgtggacgcc aagtggacca ccgcgcccat cggcgtaccg ctgcccaata cccaggcgta
    10321 cgtcgtcgac gaggcgggcc aacccgtgcc cgtgggagtg gccggcgaac tcctcattgg
    10381 gggcgacagc ctcgcccgcg gataccacgg cagggacgac ctcacacacg aggccttcat
    10441 ccccgaccac ctcggtcacc gaccgggtgc ccgtctctac cggaccggag acatcgtgcg
    10501 ccgcctgccc agcggcatcg tggaattcat cggtcgccgg gacgaccaga tcaaggtgcg
    10561 cgggttccgc gtggctctcg gggagatcga cgcggctctg atgagctgcc ccgaggtccg
    10621 gcacgcggtg accgtcgtcc gggaggacac ccccggagac cggcgaatcg tgtcctacgt
    10681 cgagccggaa cgcttcgagg agttccgccc ggatgccgta caccagcaca tccggggccg
    10741 gctcccttcg cacatgatgc cccgcgccct tgtgccgctg ccccggttac cgctctccga
    10801 ccacggcaag gtcgaccgcc gggccctgcc accgcccgtg cccgagccct cacctcccgc
    10861 cggcgcactg gccccgggaa acgacacgga gcgacgggtc gcgcaggtgt ggatgcgcgt
    10921 tctcgatgtc gccgacgtgg ggctggagca gaacttcttc gacctcggcg gtcactcgct
    10981 cctgctcgtg gaactgcagc accggttgca gcgggctctg ggcaaggaga tcgatctgct
    11041 cgacctgttc cagcacacca ccgtgcgcgc ccaggccgat ttcttctcgc gtcaggagcc
    11101 gccggtcgca catgaggacg gcaccgccgg cacccggcaa cagagggcgc tcctgaagcg
    11161 ccgccagcaa cagctgcgaa cgaagcgagg tcgccgtgag taacgacctg acggagacca
    11221 ccgtggacgc ctccgaggac agcctggaca tcgcggtcgt cggcatggcg gggcgcttcc
    11281 ccggagcgga ctccctggaa gagttttggg acaacctccg gtccgggaag tgttccgtca
    11341 cctcgttcga cgaggcgcaa ctggccgagc gcggagtgga cgcggccaca ctgggcaatc
    11401 ccgacttcgt cccgtacggc tatgtgttgg aggacgcccg gcagttcgac gcggcgttct
    11461 tcgggtactc cgcgcgcgag gccgagctga tggatccgca acaccgggtc ctcctcgagt
    11521 gtgcctgggc ggccatggag agttcggggc acgaccccga gcggtacgac ggctccatcg
    11581 gagtgttcgc aggagccggg aacaacacct acttgctgcg caacatcgcc acgcagccgg
    11641 atgccgccga actgtgcgcc gacaagcagg tggtgatcgg gaaccgctcc gacttcctca
    11701 gcagccgggt ctcctacaaa ctcggcctgc ggggccccag cgtcaatgtc cagtcggcgt
    11761 gttcgacttc cctcgtcgcc gtcgtcgagg cctgccagtc cctgctggcc taccagtgcg
    11821 acatggcgct cgccggaggg gtcgcgatcg acgactcacg ccgcgacggc tacatccacc
    11881 ggcctgacgg catcctctcc ccggacggct attgccgtac tttcgacgca cgcgcccagg
    11941 gcacggtcgg gggcgacggc gtcgggatgg tcgttctgaa acgcctcgga gacgcgatcg
    12001 cggacggcga tcacatccac gccgtcatca aaggcggcgc cgtcaacaac gacggcgccg
    12061 aacgggccgg cttcaccgcg ccgaacccgg tggcccaggc cgaggccatc gccgccgccc
    12121 tgtccgacgc ggacgtcgcg gccgagagca tccgctacgt cgaacttcac gggacagcca
    12181 ccatcctcgg cgatcccatc gagttcaagg ccctcacctc ggcgttccag ggggtaggcc
    12241 ccggcaactg cgcggtgggc tcggtgaaga ccaacatcgg gcacctcgac tccgccgcag
    12301 gcgtcgcggg actgatcaag acggtgctcg cggtggagca cggtcagata cctcccagcc
    12361 tccacttcca cacgccgaac ccacgactgg gcttggaggg cagcccgttc tacgtcaaca
    12421 cggagttact cgactggccg gaacacgagg ggccccgtcg agcgggcgtc agttccttcg
    12481 gcctcggtgg cacgaacgcc catgtggttc tggaggaagc cccaccaccg cgttccgccc
    12541 tccgcccctg cgacgaaggc gccgagcaac tgctcgtgtg gtccgcgaag agcatggaag
    12601 cgctggaggc ggcgaccgac cgactcgctg atcacctgcg cacccacccc gaccagaact
    12661 tggcggacgt ggccttcacc ctccgggccg gccggaaaag cctccccttc aggcgcatgc
    12721 ttgtgtgccg gagcggggac gaggccctag aagccatcga cgcccgggac gacggtcgtc
    12781 tgctgaccac ggccgccccc gatgtgagcg gccgtcccgt aggtttcctc tgcgccggtt
    12841 tcggatcgca gtttccggga atggcacgcg ccctgtacag ccgggaggcg gtgttccggg
    12901 aagtactcga ccgttgcgcg acccatcttc acgctctgct cggccaggac atccgccccc
    12961 tcctcctgac gggatccgac gcgccggatg cagaggccgg tacagcggtt cccgacttcc
    13021 gcagcttcct gctgcagccc gcccgcagcg atcacacgct cgatctgccc tccatcggct
    13081 acccggcggt gttcgctctg gagtacgccc ttgccgaact ctggcaggag tggggggtcg
    13141 aaccggttgc catgatcggc cacagcctgg gcgagtacgt ggccgcgtgc ctcgccggtg
    13201 tgttcgacct tccggacgcg ctgcggctcg tggtggaacg cgctcggctc atcgagaagc
    13261 agggcgaggg cgcgatgctg gccgtaccac tgagcgagga ggaggccgcc cggtacacgg
    13321 acgatgaggt gtgtctcgcc gccgtcaacg ggcctcggac ctgtgtgctg tccggcacca
    13381 tcacgggaat cgaacgcgcc agccgggaac tccaggcggc cgggctcgca tcgcgccttc
    13441 tgacgagccg gttcgccttt cactccccga tgatggatcc ggtcgtggag ccctatcggg
    13501 acgtcgtccg ctcggtacgg ctcaaccctc cgtccaagcc gttcgtgtcc aatctgacgg
    13561 gaacgtggat caccgaccag gaagccacca gccctgacta ctgggcccag cacctgcgcg
    13621 gcacggtccg tttcgcggac gggatcgcga ctctctggtc ggttccggac atcgttctgg
    13681 tcgaaatcgg tcctgccccc gtgcatacgg ccgacgtgct gcagcatcct gccgccgggc
    13741 aggtccccga ccgtgtcgtc gtcgcgtcga cgccgcggcc ccttgccgga cgaagcaacc
    13801 gggccacgct cctcgacgcg gcggggcggt tgtggctcgc cgggcaccgg caggtgttcc
    13861 cctcggctcc ggggagccgc cgggtgcccc tgcccaccta cccgttcgag cgccgcacct
    13921 actggctcgc gcccgggacc cctcggctac atgagacgtc cgcggagcag cgcgccggct
    13981 ccctgcccca gtggttctac gcacagtcct ggcaacgggc ggccgcggct ccgcctccag
    14041 acatggcgga tctgggcgcc cggcgctggc tggtcttcgt ggacggcatg ggcgtcggcc
    14101 gccggttggc gcaccggctc gaggaactgg gcgcgagcgt ggtccgcgcg gtcgccggca
    14161 ccgagtggag cgacagcggc gaccgcgagt acgtcctgca ccccggacag ccggctcatt
    14221 tcgccatgct ggccgcggcc ctgcgtgcgg acggcggcct gcccgaccgg atcgtccact
    14281 gctggagcgt cggcgacgac gcccgcggtg cggcggaacc cgaggccgcc gaggcgctgc
    14341 tcgaccgagc cttcggcagt ctgatccact gggcacaggc caccgacacc gagttgatga
    14401 cgtcccacca gcgctgggac gtggtgtcga gcgaggtgta ctcggtgatc ggtgacgagg
    14461 agctgtgccc tccgaaggcc gtggtccagg gtgtgtgccg ggttctgccg caggagtatc
    14521 cgtctgtcga ctgcgctcac ctcgacctgc gtacaggtga gggggaggaa ccggacacgc
    14581 tggcgggccg gttgctggcc gagctggccc ggcccgcggc cgagcggaca ctggccctgc
    14641 gcgggcgtca tcggtggaag ccggacttcg cccgggtctc gcctccttcc cgcggcacgt
    14701 cgccggtccg accggacggg gtttacctga tcaccggagg gctgggcaag atcggccttc
    14761 tcgtgggacg ggccctggcc gagcggtgtc gggtccggct cgtcctgctc ggcagaacgg
    14821 gcctgccgcc ccgggcgagc tgggacgact cgcagcatcc cgcagcggtg cgggaggtga
    14881 tccgcgcgat acgcgccctt gaggacctcg gctccgaggt gatggtgcgg gctgccgacg
    14941 tagccgatgc gagcgccatg gtcagggtga aggacgagat cgtccagagg ttcggctgcc
    15001 tgtccggtgt ggtgcactgc gcgggcagca cgggatccgc cgcgcaccgg agcatcaccg
    15061 acctgggacc ggaggagagc tcctggcact tcgcgccgaa ggtccacgga atgcgggtcc
    15121 tgcacgagat cctcgcggac cagaagctgg acttcgcggt catctgctcc tctgtcgcat
    15181 cgttgctggg aggactgggt tttgccgcct acgccgccgc caacgccgct ctggacgcct
    15241 tcgctcaacg tcaccacagc cctcagctcc cctggaccag cgtgaactgg gaggcatggc
    15301 tcttctcgga cgagggccgg ggcagtgccc ggatcggcgc agctgtgaag gacctggccc
    15361 tcactccgca ggaaggcagg caggtctggg acgtactgct cgacgctgtc ccggaaccgc
    15421 aggtcgtcgt gtcgaccgga gacatgtccc ggcgtcacgc gctgtggtcc gcgcccgtcg
    15481 ccggtgagcc tgcggtccgc cgttacgcgc gccccgatct cagcaatccg ttcgtggccc
    15541 cggcgggtgc gtcggagcac cgcatagccg agatatggca ggaactcatg ggcgtggacc
    15601 gcgtcggggc acacgacaac ttcttcgaac tcggggggag ttcgctgctc gggctgcagg
    15661 tcgtgcaccg gctccgccgg gacctgggcg tggcggtgcc gttgaccatc gtctacgagg
    15721 gccccaccgt acgcacgctc ggtgcgctgg tcgaccaggt cagggaggat cgttgatgga
    15781 ccgtcgcggt ggtgtggcga tcatcgggat ggcggggcgc ttcccgggtg cccgggacct
    15841 gacggagttc tgggagaacc tgcgggacgg tgtggagtcg atc
//
