LOCUS       reptomyces_RBGC_685423 16798 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_685423
VERSION     Streptomyces_RBGC_685423
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000725565.1
  ORGANISM  GCF_000725565.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..318)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63673"
                     /pseudo=False
                     /translation="VAASAQLLLDALSSAPEYPAARSESCGPEKNEPEKPTEPDLFDGV
                     SDPDSGLDGSGSLCFCEPPLTSEPPLADAAPLTSESPIAAELPLTSEPTAAGLGTESME
                     V*"
     CDS             812..4200
                     /protein_domains="PF07555"
                     /protein_domains="PF02838"
                     /protein_domains="PF00754"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63674"
                     /pseudo=False
                     /translation="VRVRNGVRDAGEVGRQGERAGSGGTRPGGAGDDRARARPGAPMDG
                     GAYRTDLADGSCPTGPTSIGTGSIGRLGSVRARARTRVAGATALAAAVIGGLLAGTAPA
                     HAAPADPVVGTPDLPGQNDGRTTSAGQLPAVWPRPQSMRAGGTAVRLGDEAAVVAAPDA
                     DPYALEALRALLRDAGVRTVHDVAPGQQPPGDGPVFRLGGADAETALKALRAPARGDLP
                     SGGYRLAVGEAAGRDTVALDGVGPDGLFHAVQTLRQLLVDRSSGGREKGDGGKELAPAV
                     VRDWPGTAVRGMTEGFFGQPWTPQQRLDQLDFMGRTKQNRYLYAPGDDPYRQFRWREPY
                     PAAQRDDFRALAERARANHVTLAWAVSPGQAMCMSSEDDIKALRRKVDAMWALGVRAFQ
                     LQFQDVSYSEWHCDADADTFGSGPEAAAKAHAKVADALAEHLAEKYPGAAPLSLMPTEY
                     YQDGSTAYRDALAAALSDRVEVAWTGVGVVPRTITGAELSKARQAFGHPMVTMDNYPVN
                     DYAQDRIFLGPYTGREPAVATGSTALLANAMAQPTASRVALFTAADFAWNPRGYRPGAS
                     WQAAVDDLAGGDAASRAALHALAGNDASSVLGTDESAYLKPLIETFWKTRAAATNSGDR
                     DDDERYTQAAARLRAAFHTMSGAPERLAPALADEVRPWARQLARYGSAGERAVDMLVAQ
                     ARGDGAAAWSAQRAVQDLRKKIKKSPATVGKGVLGPFLDRAMTESDAWTGAASETGARP
                     DTTPQPQEGADPTSLSVPFGRPRPLTAVTALTEPSPSSAAISVEAHVPGEGWRRLGGLS
                     DTGWTQTEARGLKADAIRMAWKDGTAPPSVHSFTPWFADTPAAGLELSRDTLDADTGGT
                     ASVDALIFSRRPADVEGKLTAKAPKGFTVRAPEHVTAPRGGTATVRIQITVPKDARSGT
                     YEIPVTYGDQKQTLTLRTYPPTAGPDLARGATATSSGDEAPEFPATAATDGDPKTRWSS
                     PAQDDAWLQLELPRPVRLGRLVLTWQEAHAAAYRVQVSADGVTWRTAATVRDGKGGRET
                     VRMDAEDTRYVRIQGDKRATRFGYSLWSVEAYAVKGTDQQKPEPPRPPGNSRPGTPARP
                     GSAGDASGGAPSADGQWPGGGR*"
     CDS             complement(4280..4815)
                     /protein_domains="PF14279"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63675"
                     /pseudo=False
                     /translation="VPHVLVLNASYEPLGVVPLRRALILVLNEKAVSLEESGALMHSAT
                     RVMPAPSVVRLKRFVRVPFRGPVPLTRRALFARDGGRCMYCGGVATSVDHVVPRSRGGQ
                     HTWENVVAACRRCNHVKADRHVAEIGWRLRHQPAPPSGLAWRIIGTGHRDPRWLPYLQP
                     YGADDALARIDAVSA*"
     CDS             5094..6160
                     /protein_domains="PF00924"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63676"
                     /pseudo=False
                     /translation="VFWSASPAAATPGPHRRASLDDATEKATNAAGWVEENWATWLTSA
                     LQIALIIVIAVILRHVIRRTITKLIERMNRTATAAQGTALGGFLVNAERRRQRSEAIGS
                     VLRSVASFVIMGTAALTVLSVLKINLAPLLASAGVAGVAIGFGARNLVTDFLSGVFMIL
                     EDQYGVGDEIDAGVATGTVVEVGLRVTKLRGPNGAIWYIRNGEVKRIGNLSQGWSTATV
                     DVMIAPNQDLDRAREVITAVGEEMSKAEPWNEQLWEPVEVLGLSEVHLDSVTISVSAKT
                     MPGKALGIERELRWRIKKALDTEGITLAPRPTTPLTDETTPDPSAAVAAPSALASPTSP
                     QSLAAAPIPAPNLSK*"
     CDS             complement(6255..6718)
                     /protein_domains="PF14433"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63677"
                     /pseudo=False
                     /translation="MTVTTRPRGEVERWLVRNGWEPGRDVSGRVAEFIECAEDWANREG
                     FPAPVFDAARDFLRSYGLLELKAEKHPGRSLEINPAGGHEGDYESIAELTEELGVRLFR
                     VGFDMPECGRILMDEAGRFYYLHWSGSYVLGNDVYEALGNWLVNNLEELD*"
     CDS             6843..7375
                     /protein_domains="PF01799"
                     /protein_domains="PF00111"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63678"
                     /pseudo=False
                     /translation="METEIRLRVDGQEYEVVVDTRTTVLDALRERLGITSPKKGCDHGQ
                     CGSCTVLLDGRRATTCLALAVAHDGAEIVTAEGLGTDGELHPVQQAFVDHDALQCGYCT
                     PGQVCSAVGVLREAAQGWPSVVTEVGAEGDIAPEHLDHVEIAERMSGNLCRCGAYVNIV
                     PAVAAAAEAEGAGR*"
     CDS             7373..8388
                     /protein_domains="PF00941"
                     /protein_domains="PF03450"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63679"
                     /pseudo=False
                     /translation="VKPFRYERATDAAHAVATVAAHPGAAFLGAGTNLVDHLKLGITSP
                     DLLVDVSRLPLDEVTELDGGGLRVGANVRNADLAAHPAVRARYPVLSQALLSGASGQLR
                     NLATTGGNLLQRTRCAYFQDPSTPCNKRDPGSGCAALEGWTRYHAILGASSHCVAVHPS
                     DMAVAMAALEAVVVTLGPDGERRIPVTEFHRLPGDAPHRDTVLRHGELITAVELPALPW
                     AARSRYRKVRDRASYAFALVSVAVALDLEDDGRTVREARIALGGIAHKPWRAERAEQAL
                     RGLPATEENCRTAADAETADAHPLRDNAFKIPLVHNTLAAVVRDLVPEAPGRLEGAR*"
     CDS             8386..10499
                     /protein_domains="PF02738"
                     /protein_domains="PF02738"
                     /protein_domains="PF01315"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63680"
                     /pseudo=False
                     /translation="MTSTSESRAVGADIERADARAKVAGRAPYAFEHPVDNPCYAHAVL
                     SSIPRGRITAVDTGAALQEDGVITVLTYENAERLASTEDAELAILQEPEVAFRGQIVAA
                     VVAGTPETARHAASLVRITYATEPHESELKPDENELYRPESANGGAETDSMLGDLEAAM
                     EAAAADPDAVTLDETYVTAMTHCNPMEPHATIAVWQGDELTLYDSSQSVHGHRDTLAEV
                     FGLDRARVHMICPYVGGGFGSKGEPHAHAVLAALAARAVPGRPVKFALTRQQMFTLVGY
                     RTPTYQRVRLAAGADGRLAGIGMDAVEQTSRIKEFAEQSANPTRTMYAAQHRRTTHRLA
                     HLDVPVPSWMRAPGECPGMFGPEVAMDELAERLGMDPVELRIRNDAPVDPESGKPFSSR
                     NLVACLNEGARRFGWQDRDPRPGVRRDGRWLVGTGVASSAYPVNRVPGSVAAVEYVGEG
                     RYRVDIAAADLGTGAWTVLAQIAADRLDVPLDAVELRIGDTALPKATVAGGSAGTAMWG
                     SAIVAAAQTFRKRHGHDPSPGDHAQAETPGNPHAERFAMHAFGAQFVEVRVDADTGEIR
                     VPRLLGVFAAGRIINPRTARSQLIGGMTMGLSMALHEETVTDPRYGLLVNHDLANYHVT
                     ANADVHRIEAHWIDEDDPYVNPLGIKGIGEIGITGTAAAVVNAVRHATGVRVREVPVTL
                     DKVVGGLPGR*"
     CDS             10600..10784
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MGPELGQLVKDQVVPGPRGHCHAEPTPTAAHASMIDCQCRAVHCF
                     QHDESVSDEGSTGADR"
     CDS             10782..11413
                     /protein_domains="PF14435"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63681"
                     /pseudo=False
                     /translation="MNGTATETGRQAGAAAVNREALLAAALEPTAEWLESIFGAGALWR
                     PTEDELPERLEHAETRTFLTEVGFPSVHLAFVDYDSTDLAQEGLWAEDPDELFGNRYPD
                     DDSPPKSYAYGMGESLNYSLMLMGNTGSISLYDPNGWDHAAGYAGHVADSLPLLAGALG
                     LLASYEDRLFGGDHEAVLHELRELIDEIDPVEGCRFWEEIFQWLEDQ*"
     CDS             complement(11418..11614)
                     /protein_domains="PF04149"
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_63682"
                     /pseudo=False
                     /translation="VNLVNVPWRKSTYSGGQGECLEIADGLPTGSPVPVRDSKRPDGPH
                     LLFPAPAWAAFIASVKAARG*"
     CDS             12122..13314
                     /protein_domains="PF00480"
                     /protein_domains="PF12802"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63683"
                     /pseudo=False
                     /translation="MATGQGGQGTPGTPRVLRAMNDRAALDLLVAQGPLTRTQIGALTG
                     LSKPTASQLLGRLEAAGLVRTTGNVTGRPGPNAQLYEVNPDAAYVAALAVDQCGITAAV
                     ADVTGRVLGEERVGTEAVEEDAPPRTAQLVASAVDGALDKAGLTRERLHGAVIGTPGAL
                     DPQTGVLRYAPHLPGWHARALKDELAGVLGVPIVIENDVNLAAVAEQHDGAAQDFDDFV
                     LVWADEGVGAAIVLGGQVLRGATGGAGEIGYMPLPGAPLARGGERDAARPDAGGGFQRL
                     VGSPSIVELAQEYGAADVRTVDEALDDDRVRAEVARRLATGLAAVVAVVDPRLVVLSGE
                     VAQVGGEPLRELVEEEFTGLALPRPEIRISNIEGNPILTGALHTALAEARNAVFDTA*"
     CDS             13542..14881
                     /protein_domains="PF01547"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63684"
                     /pseudo=False
                     /translation="MPRPRMRICLSAALAGAGLILSGCANPSVGSDRDDPSQPVTLKFW
                     HGWSNPAEVKAVDDSISRFEKLHPNIKVKTVNNVTDETVNQALRAGGDDAPDVVSSFTT
                     NNVGQYCSSGMWVDLDPFMKKTGVEKAKVFPKTFLDYTSYQGKQCALPLLADAYGLYYN
                     KDAFKEAGIERPPRTMSEFKRDAAKLTKRKPDGSYERAGFMPNFRLYQNSPDRLFAQWG
                     PTYFDKKGKAQLAKDPRTKQFLATQRELMGAQGGYAALEKFRTTFGDEMSPQSSFMSQK
                     AAMHMDGEWRGLMLKEGKAKFDWGTAPLPVPDDQADTYGRGYLTGTVAGIAHSSKHQNA
                     AWELVRFLTVDTDQVVRFANAIHNVPSTFAALTSPKLDADPSFRTFIDIARNPHSQAMP
                     PSINGGQYITAFQDFAYNAEAGKVPDLGKGLRDLDAQIDADNLQSVN*"
     CDS             14895..15883
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63685"
                     /pseudo=False
                     /translation="MSLVESPERPAATAPRPKAPALRRKHLGQRLRTLGFLSPWLVGFS
                     VFFGYPLLATVYFSFMHYNQIQQPSFVGLRNWKYVFTQMPLFGPALWNTLWLVVVMVAL
                     RVVFGLGIGLLVTKIKSGVGFFRTAFYLPYLAPPVAATVAFVFLLNPGTGPVNEILEAV
                     GIPAPGWFNDAAWAKPSLVMLSLWGIGDLMVIFMAALLDVPKEQYEAAELDGAGAWARF
                     RYVTWPSITPIVLFAVVTGVVQTMQYYTQALVAGKLASGVTIGPGTVIQPGYPDHSTLT
                     VPQLVYSLGFQNFNTGAACVLSLVLFVIAMAVTTLLMRKRAGLLPAED*"
     CDS             15891..16798
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_63686"
                     /pseudo=False
                     /translation="MTTTTLRAGSAPARTGTTDRGPAASRARRKRLLHWIAVHSVAVAA
                     ALFFVLPFVFVFLTSVMSDDQAMSGELWPHEWNWSNYATVFATPGFLDWWRNSLMYAGL
                     GTLFTVGSAIPVAYALAKFRFRGRRTAMLLVISTMMLPPQVIVIPMYLVWAQQLHLSGS
                     LWPLIIPMAFGDAYSIFLLRQFLLTIPQEYIESAKVDGCGEVRTLLRIVVPMAKPGIAA
                     VALFQFFYCWNDYFGPQIYAAQNPAAWTLSYGLESFKSAHNVNWNLTMAATLLVMAPVI
                     IVFFFAQKAFVEGVTLTGVKG*"
ORIGIN
        1 tcagacctcc atggactccg tgcccaggcc ggccgcggtg ggctcgctgg tcagcggaag
       61 ctcggcggcg atcggggact cactggtgag cggggcggcg tcggcgagcg ggggctcgct
      121 ggtcaggggc ggttcgcaga agcacaggga gccggagccg tccaggccgg agtcggggtc
      181 ggagacgccg tcgaacagat ccggctcggt gggtttctcg ggctcgtttt tctccggtcc
      241 gcaggattcg ctgcgcgctg cggggtactc gggggcggac gacagtgcgt cgaggaggag
      301 ctgagcggac gcggccacgg agggcctccc gttcgtcggt agtgggacac gacctgccct
      361 acccactcgg ggcggtcgca gacgtaccca ttcaatcaac gtggcccagg tcacacatcc
      421 ctcgtgcagg cgatttaccg gtggcggacg ggtggcggcg cagagatgcc caccggaggg
      481 gcgatccgga ggaagtcctc cggggcggtc gggcggggtg tgccgccagg ggtggagcac
      541 ggaggacgcc gcccgcggca ctcactcgac gcgccgcgac acgccggtca cacagggcaa
      601 acccggcact tcgccttccg ccgttgacac cctcaccacc acagtggtgg gctcactgcc
      661 gaaggcttgt ccggcggggt tccacggggt gcagggcccc gtcgcggcag tcggctcagg
      721 ggcgcgcggc cgcggggcgg ccgggcagcg ggcggccggt gcggacaccg gtcgaccggt
      781 gagtaggaat acggggactg aggagtgacc gtgcgagtcc ggaacggcgt tcgggacgcc
      841 ggagaggtcg gcaggcaggg cgagagggcc gggagcggcg gtacgcggcc gggcggggcc
      901 ggggatgacc gcgcgcgtgc gcggccgggc gctcccatgg atggcggtgc gtaccgtacg
      961 gacctggccg acggctcctg ccccaccggc cccaccagca tcggcaccgg cagcatcggc
     1021 cgcctcggtt ccgtacgggc gcgggcccgc acgcgcgtgg ccggggccac cgccctggcc
     1081 gccgcggtga tcggcgggct gctcgccggc accgcccccg cccacgcggc gcccgccgat
     1141 ccggtcgtcg gcacgccgga cctgcccgga cagaacgacg gccggaccac gtccgccggg
     1201 cagttgcccg ccgtgtggcc gcgcccgcag tcgatgcgcg cgggcggcac cgccgtacgg
     1261 ctgggcgacg aggccgccgt cgtcgccgcg ccggacgccg acccgtacgc cctggaggcg
     1321 ctgcgcgccc tgctgcgcga cgccggggtc cgtacggtcc acgatgtcgc cccggggcag
     1381 cagccgcccg gcgacggccc ggtcttccgc ctcggcggcg cggacgcgga gaccgcgctg
     1441 aaagctctgc gcgcgcccgc ccgcggcgac ctgccgtccg gcggctaccg cctcgcggtc
     1501 ggcgaggccg cgggccggga caccgtcgcg ctggacggcg tcggcccgga cggcctcttc
     1561 cacgccgtac agaccctgcg gcagctcctc gtggaccgct cgtccggggg ccgcgaaaag
     1621 ggggacggcg gcaaggagct ggcccccgcg gtcgtccgcg actggccggg caccgccgtc
     1681 cgcggcatga ccgagggctt cttcggccag ccctggaccc cgcagcagcg cctggaccag
     1741 ctcgacttca tgggccgtac gaagcagaac cgctacctct acgcgcccgg cgacgacccg
     1801 taccgccagt tccgctggcg tgagccctac cccgcggcgc agcgcgacga cttccgggca
     1861 ctggccgagc gggcccgcgc caaccacgtc acgctggcct gggccgtctc ccccggccag
     1921 gccatgtgca tgtcctccga ggacgacatc aaggcgctgc gccgcaaggt ggacgcgatg
     1981 tgggcgctgg gcgtgcgcgc cttccagctc cagttccagg acgtcagcta cagcgagtgg
     2041 cactgcgacg cggacgccga cacgttcggc tccggcccgg aggccgccgc caaggcgcac
     2101 gcgaaggtgg cggacgcgct cgccgaacac ctcgccgaga agtaccccgg cgcggcgccg
     2161 ctctccctca tgccgaccga gtactaccag gacggctcga ccgcctaccg ggacgcgctc
     2221 gccgccgcgc tgtccgaccg ggtcgaggtc gcgtggaccg gcgtcggcgt cgtcccgcgc
     2281 accatcacgg gcgccgaact gagcaaggcc cgccaggcgt tcggtcatcc gatggtcacg
     2341 atggacaact atccggtcaa cgactatgcg caggaccgta ttttcctcgg cccctacacg
     2401 ggccgcgaac ccgccgtcgc caccggctcc accgccctgc tggccaacgc catggcgcag
     2461 cccacggcgt cccgcgtcgc gctgttcacc gccgccgact tcgcctggaa cccgcgcggc
     2521 taccggcccg gcgcgtcctg gcaggccgcc gtcgacgacc tggcgggcgg cgacgccgcc
     2581 tcccgcgccg cgctgcacgc gctggccggc aacgacgcct cctcggtcct cggcaccgac
     2641 gagtccgcgt atctcaagcc gctgatcgag acgttctgga agacccgcgc cgccgccacc
     2701 aacagcggcg accgggacga cgacgagcgc tacacccagg ccgccgcccg gctgcgggcc
     2761 gccttccaca cgatgagcgg cgccccggag cggctcgctc ccgctctggc cgacgaagta
     2821 cgtccctggg cccgccaatt ggcccgctac ggttcggcgg gcgagcgtgc cgtggacatg
     2881 ctggtggcgc aggcccgggg ggacggcgcc gccgcgtggt ccgcgcagcg cgccgtgcag
     2941 gacctgcgca agaagatcaa gaagagtccg gcgacggtcg gaaagggtgt tctcgggccc
     3001 ttcctcgacc gcgcgatgac cgagtccgac gcctggaccg gtgccgcctc cgagaccggc
     3061 gcccgccccg acaccacgcc acagccccag gagggcgccg acccgacctc cctgtccgtc
     3121 ccgttcggcc gcccccgccc gctgaccgcg gtcaccgcgc tcaccgaacc gagcccgtcc
     3181 tcggccgcca tctccgtgga ggcgcacgtc cccggcgagg gctggcgccg cctcggcggc
     3241 ctgtccgaca ccggctggac gcagaccgag gcgcgcgggc tgaaggccga cgcgatccgg
     3301 atggcctgga aggacggcac cgccccgccg tccgtccact ccttcacccc gtggttcgcc
     3361 gacaccccgg cggcgggcct ggaactgtcc cgggacaccc tcgacgccga caccggcggc
     3421 accgcctccg tggacgccct gatcttctcc cggcgccccg ccgacgtgga gggcaagctc
     3481 accgccaagg cacccaaggg gttcaccgta cgggcgccgg agcacgtcac ggccccgcgc
     3541 ggcggcacgg ccaccgtccg tatccagatc acggtcccca aggacgcgcg gtccggcacg
     3601 tacgagatcc cggtgaccta cggcgaccag aagcagaccc tgaccctgcg cacctatccg
     3661 cccaccgcgg ggcccgacct ggcccgcggc gccacggcca cctcctccgg cgacgaggcg
     3721 cccgagttcc cggccaccgc cgccaccgac ggcgacccga agacccgctg gtcctccccc
     3781 gcccaggacg acgcctggct ccagctcgaa ctgccgcgcc ccgtccgcct cggccgcctg
     3841 gtcctcacct ggcaggaggc gcacgccgcc gcctaccgcg tacaggtctc cgcggacggc
     3901 gtcacctggc gcacggcggc caccgtccgc gacggcaagg gcggccgcga aaccgtccgc
     3961 atggacgccg aggacacccg ctacgtccgt atccagggcg acaagcgggc cacccgcttc
     4021 ggctactcgc tgtggagcgt ggaggcgtac gcggtgaagg gcacggacca gcagaagccg
     4081 gagccgcccc ggccaccggg caactcccgg cccggcacgc ccgcccggcc cgggtccgcc
     4141 ggagacgcgt ccggtggcgc cccgtcagcc gacgggcagt ggccgggcgg cggccggtag
     4201 acgacgcgca ccccggagcc cgggcccgga cgacgtccgg gcccggccgg gaaagccccg
     4261 ccatgcaaaa acccggacct atgccgatac ggcatcgatc cgggccagcg cgtcgtccgc
     4321 cccgtacggc tgcagatatg gcagccaacg ggggtcccta tgccccgtac cgatgatccg
     4381 ccaggccagg ccggacggcg gggcgggctg atgccgcagc cgccagccga tctcggcgac
     4441 atgccggtcg gccttgacat ggttgcagcg gcggcaggcg gcgaccacgt tctcccaggt
     4501 gtgctggccg ccgcgactgc gcgggacgac gtggtcgacg ctggttgcga cgccaccgca
     4561 gtacatgcac cgtccgccgt cacgggcgaa cagggctcga cgggtcaggg ggacgggacc
     4621 gcgaaagggc acccgcacga accgcttgag gcggaccaca ctcggggcgg gcatcacacg
     4681 ggtcgcgctg tgcatcaggg cgccggactc ctcaaggctc acggcctttt cattgaggac
     4741 gaggatgagc gcgcggcgga gcggtacgac gccgagcggc tcgtacgacg cgttgaggac
     4801 caggacatgc ggcacgggtg cctccttgta cgccggcggc gcgtggctcg cgccgggacg
     4861 atctccccac agtgtccccc ggtgcctggt cgcggcgcca ccatcaccgg gtaacgggtc
     4921 cgaggtgttt tcgaccacac gcctttactt ccccccaaaa agtcccgcaa ttggtccggt
     4981 cactctcgaa caccggcgcg gaccgccccc gttgccccgt tagtgtggtt ggtctgcccg
     5041 ggtcacggtc cgtcccgacc ctggtctgct gtcccacacg gaggtccctg ctgtgttctg
     5101 gtccgcttcc ccagccgccg cgacgcccgg cccgcaccgc cgcgcgtcgc tcgacgacgc
     5161 cacggagaag gccaccaacg ccgccggatg ggtggaggag aactgggcga cctggctcac
     5221 ctccgccctg cagatcgcgc tgatcatcgt catcgccgtc atcctgcggc atgtgatccg
     5281 gcgcacgatc accaaactca tagagcggat gaaccgcacc gcgacggccg cccaaggcac
     5341 cgcgctgggc gggttcctgg tcaacgccga gcgccgccgg cagcgctccg aggccatcgg
     5401 ctcggtactg cgcagcgtcg cctccttcgt catcatgggc accgccgcgc tcacggtgct
     5461 gtccgtcctg aagatcaacc tggcgccgct gctggccagc gccggcgtcg cgggcgtcgc
     5521 catcggcttc ggcgcccgca acctcgtcac cgacttcctc tccggcgtct tcatgatcct
     5581 ggaggaccag tacggcgtcg gcgacgagat cgacgcgggc gtggccaccg gtacggtcgt
     5641 cgaggtcggc ctgcgcgtca ccaagctgcg cggcccgaac ggcgccatct ggtacatacg
     5701 caacggcgag gtcaagcgca tcggcaacct cagccagggc tggtccaccg ccaccgtcga
     5761 cgtcatgatc gccccgaacc aggacctgga ccgcgcccgc gaggtcatca cggccgtcgg
     5821 cgaggagatg tccaaggccg aaccctggaa cgaacagctc tgggaaccgg tcgaggtcct
     5881 cggcctcagc gaggtccacc tcgactccgt cacgatcagc gtctccgcca aaaccatgcc
     5941 cggcaaggcc ctcggcatag aacgcgaact ccgctggcgc ataaagaagg ccctggacac
     6001 cgaaggcata accctggccc cccgccccac cacccccctg accgacgaga caaccccgga
     6061 ccccagcgcc gcggtggccg caccgtcggc cctggcaagc ccgacgtcgc cgcagtcgct
     6121 ggcggctgcg cctattccgg cgcctaattt gagtaagtag ggtgcctgcc cgctgagacg
     6181 gcaccgcccc ggcccgaatc gatgcggacc ggggcggttt gcgtagggcg actccgctcg
     6241 cgggccgccg aggtcagtcc agctcttcga ggttgttcac cagccagttc ccgagcgcct
     6301 cgtacacgtc gttccccagg acgtagctgc ccgaccagtg cagatagtag aagcgaccgg
     6361 cctcgtccat caggatcctg ccgcactccg gcatgtcgaa tcccacccgg aacagccgga
     6421 ctcccagctc ttcggtaagt tccgcgatgg actcgtagtc accttcgtga ccgcccgccg
     6481 gattgatttc cagggaacgg cccggatgct tctcggcctt cagctccagc aggccgtagg
     6541 accgcagaaa gtctctggca gcgtcgaaca ccggcgccgg aaatccctcc ctgttcgccc
     6601 agtcctcggc gcattcgatg aattcggcaa cgcgcccgga aacatccctc cccggctccc
     6661 acccgttccg taccagccac cgttccactt ccccgcgtgg cctcgtcgtc accgtcatcc
     6721 gcacactcct ccacccccac agccacgacc acctcgttaa gcccgttcag cccactgtcc
     6781 cactcacgca tcacccacat gcccccgttt accaccccct cccccggtga ctcgcttcac
     6841 catggagacc gagatcaggc tgcgcgtgga cgggcaggag tacgaggtcg tggtggatac
     6901 gcggaccacc gtgctggacg cgttgcggga gcggctgggg atcaccagtc cgaagaaggg
     6961 gtgcgatcac gggcagtgcg ggtcgtgcac cgtactgctg gacgggcggc gggcgacgac
     7021 gtgcctggcg ctggccgtgg cgcacgacgg ggcggagatc gtcacggcgg aggggctggg
     7081 tacggacggc gaactgcatc ccgtacagca ggccttcgtg gatcatgacg cgctgcagtg
     7141 cgggtactgc acgccggggc aggtgtgttc cgcggtgggg gtgctgcggg aggcggcgca
     7201 gggttggccg agtgtggtca ccgaggtggg cgcggaaggc gacatcgcgc ccgagcatct
     7261 cgatcatgtg gagatcgccg agcggatgag cggcaatctg tgccggtgcg gggcgtatgt
     7321 gaacatcgtt ccggcggtcg ctgccgccgc cgaggccgag ggagcaggcc ggtgaagccg
     7381 ttccggtacg aacgtgccac cgacgccgcg cacgcggtgg cgaccgtggc ggcgcacccg
     7441 ggggccgcgt tcctcggcgc cggcaccaat ctcgtcgatc atctgaagct cggcatcacc
     7501 tcccccgacc tgctggtcga cgtcagccgg ctgcccctgg acgaggtgac ggagctggac
     7561 ggcggcggcc tgcgggtggg cgcgaacgtc cgtaacgccg atctggccgc gcaccccgcc
     7621 gtacgcgccc gctaccccgt gctctcccag gccctgctct ccggcgcgtc cgggcagctg
     7681 cgcaacctcg cgaccaccgg cggcaacctc ctccagcgca cccgctgcgc ctacttccag
     7741 gaccccagca ccccgtgcaa caagcgcgac cccggctccg gatgcgccgc cctggagggc
     7801 tggacccgct atcacgccat cctgggggcg tcctcgcact gcgtggccgt gcacccctcc
     7861 gacatggcgg tggcgatggc cgccctggag gccgtggtcg tgaccctggg cccggacggc
     7921 gagcgccgta tcccggtcac cgagttccac cggctgcccg gcgacgcgcc gcaccgcgac
     7981 accgtgctcc ggcacggcga gctgatcacc gccgtcgagc tgcccgccct gccgtgggcg
     8041 gcccgctccc gctaccgcaa ggtgcgcgac cgcgcctcgt acgccttcgc gctggtctcc
     8101 gtggccgtgg ccctcgacct ggaggacgac ggccgcaccg tacgggaggc gcggatcgcg
     8161 ctgggcggga tcgcgcacaa gccgtggcgg gccgagcgtg ccgaacaggc cctgcgcggg
     8221 ctgccggcca ccgaggagaa ctgccggacg gcggccgacg ccgagacggc cgacgcccat
     8281 ccgctgcggg acaacgcgtt caagatccca ctcgtccaca acacgctggc cgccgtcgta
     8341 cgcgatctcg taccggaggc tccgggccgc ctggaggggg cacgatgacg agcacatccg
     8401 agagccgggc cgtcggcgcg gacatcgaac gcgcggacgc ccgggccaaa gtggccggcc
     8461 gggccccgta cgccttcgaa caccccgtgg acaacccctg ctatgcccac gccgtgctgt
     8521 cctccatccc gcgtggccgc atcacggccg tcgacaccgg ggccgcgctc caggaggacg
     8581 gcgtcatcac cgtactgacg tacgagaacg ccgagcggct ggcgtccacg gaggacgcgg
     8641 aactggcgat cctccaggag cccgaggtgg cgttccgcgg gcagatcgtg gcggcggtgg
     8701 tcgccgggac gcccgagact gcgcggcacg cggcgtcact cgtacggatc acctacgcca
     8761 ccgagccgca cgaatccgag ctgaaaccgg acgagaacga gctgtaccgg ccggagtcgg
     8821 ccaacggtgg cgcggaaacc gacagcatgc tgggcgatct ggaagccgcc atggaggcgg
     8881 ccgcggcgga cccggacgcg gtgacgctgg acgagacgta cgtgaccgcg atgacccact
     8941 gcaacccgat ggagccgcac gcgacgatcg ccgtgtggca gggagacgag ctgacgctgt
     9001 acgactcgtc ccagagtgtg cacgggcacc gcgacaccct ggccgaggtg ttcggcctcg
     9061 accgcgcccg cgtgcacatg atctgtccgt acgtcggcgg cggcttcggc tcgaagggcg
     9121 agccgcacgc ccatgccgta ctcgccgcgc tggcggcgcg cgcggtgccc gggcggccgg
     9181 tgaagttcgc gctgacccgg cagcagatgt tcaccctcgt cggctaccgc acgcccacgt
     9241 accagcgggt acgcctcgcg gccggggccg acgggcggct ggccggcatc ggcatggacg
     9301 ccgtcgagca gacctcgcgc atcaaggagt tcgccgaaca gtccgccaac ccgacgcgga
     9361 ccatgtacgc ggcgcagcac cggcggacca cccaccggct ggcccacctg gacgtgccgg
     9421 tgccgtcctg gatgcgggca cccggcgagt gccccggcat gttcgggccc gaggtcgcca
     9481 tggacgaact ggccgaacgc ctcggcatgg accccgtcga gctgcgcatc cgcaacgacg
     9541 cgccggtgga cccggagtcc ggcaagccct tctccagccg caacctggtg gcgtgcctga
     9601 acgaaggcgc ccgccgcttc ggctggcagg accgcgaccc gcgccccgga gtacggcggg
     9661 acggccgctg gctggtcggt acgggcgtcg cctcgtcggc ctacccggtc aaccgcgtgc
     9721 ccggctcggt cgccgccgtc gagtacgtgg gcgaaggccg ctaccgggtg gacatcgccg
     9781 cggccgacct gggcaccggt gcctggaccg tactcgccca gatcgccgcg gaccggctgg
     9841 acgtccccct cgacgccgtc gaactgcgca tcggcgacac cgcgctcccc aaggcgaccg
     9901 tcgcgggcgg ctccgccggt acggcgatgt ggggctcggc gatcgtggcg gcggcgcaaa
     9961 ccttccgtaa gcgccatgga cacgacccgt cccccggcga ccacgcgcag gccgagaccc
    10021 ccggcaaccc gcacgccgaa cgcttcgcca tgcacgcgtt cggcgcccag ttcgtcgagg
    10081 tacgggtgga cgccgacacc ggcgagatcc gcgtaccgcg cctcctcggc gtcttcgcgg
    10141 ccggccgcat catcaacccg cgcaccgccc gctcccagct gatcggcggc atgacgatgg
    10201 gcctgtccat ggccctccac gaggaaaccg tcaccgaccc gcgctacggc ctcctcgtca
    10261 accacgacct ggccaactac cacgtcacgg ccaacgcgga cgtccaccgg atcgaggccc
    10321 actggatcga tgaggacgac ccgtacgtca accccctggg catcaagggc atcggcgaaa
    10381 tcggcatcac gggcacggcg gcggccgtcg tcaacgcggt ccggcatgcg acgggggtgc
    10441 gggtgcggga ggtgccggtg acgttggaca aggtggtggg cgggctgccc ggccggtgac
    10501 cgccccgggc cggtcctcgg ggcggcccgc agccggcact ccgggccggg agcaaccgcg
    10561 ccccggcagg aggcggccct cctctcgcag ccgagcccat gggcccagaa ctcgggcagc
    10621 tcgtgaaaga tcaggtcgtg cccggcccgc gggggcactg ccatgccgaa cccacgccca
    10681 ccgctgccca tgcatccatg atcgattgtc agtgccgtgc ggttcactgt tttcagcacg
    10741 acgaatcggt ttcggacgaa ggaagtacgg gggctgaccg atgaacggga cggcaacgga
    10801 aacgggacgg caggcgggcg ctgccgccgt gaatcgggag gcactactgg ccgcggccct
    10861 ggagccgacg gcggagtggc tggagtcgat attcggggcc ggggcgctgt ggcggcccac
    10921 ggaggacgaa ctccccgagc gactggaaca cgcggaaacc cgcacgttcc tcaccgaggt
    10981 cggattcccg tccgtccacc tcgccttcgt ggactacgac tccaccgacc tggcccagga
    11041 aggcctctgg gccgaagacc cggacgaact gttcggcaac cgctacccgg acgacgactc
    11101 cccgccgaag tcctacgcct acggcatggg cgagtcgctg aactactccc tgatgctcat
    11161 gggcaacacc ggcagcatct ccctgtacga ccccaacggc tgggaccacg cggccggata
    11221 cgcgggccac gtggccgaca gcctgccgct gctcgcgggg gcactgggcc tgctggcgtc
    11281 ctacgaggac cggctcttcg gaggtgacca cgaggcggtc ctgcacgagc tccgcgaact
    11341 gatcgacgaa atagatccgg tggaggggtg ccggttctgg gaggagatat tccagtggct
    11401 ggaggaccag tagccgtcag ccgcgggccg ctttcacgga ggcgatgaag gcggcccagg
    11461 cgggggcggg gaagaggagg tgcgggccgt cggggcgctt gctgtcgcgt acggggacgg
    11521 gcgagccggt cgggaggccg tcggctatct ccaggcactc gccctggccg ccgctgtagg
    11581 tgctcttgcg ccacgggacg ttgacgaggt tcacgctcgg tgctccttgg cgatgcgctg
    11641 gtcccgttcg gttcggcggg tgagagcgca ggagtacgcg gtagcgcgca tccctggctc
    11701 cgctcgggtc acgccgctct ccgcccgtac gacatccagc gccggtacct ccgggaagct
    11761 cagcagcaag tacggtccga acgtactgcg ttgcgctcct cgggagaacg gcagaacctg
    11821 aactgtgacg tcgagttgtc ggccatggtc acagaatggt cgggtgggcc acggatggaa
    11881 cccctatcac ccggccccaa cccactcgac gaacacggcc ggggcatggt gctcgttgac
    11941 gcgctggcgg acgactgggg agtgacgggc cgccccgggc cgggtaagac cgtctggggt
    12001 gctctcaaag tcaatggtcc agacccattg acgtcctgct gacgtggcgc ttacgttcct
    12061 gtgcatcgat tggaaacttt cctaacagat cgcagcggag cgagaatcgg ggcgggcgtg
    12121 atggccacag ggcagggcgg gcaggggacc cctggtacgc cgcgggtgtt gcgggccatg
    12181 aacgaccggg ccgcgctcga cctgctcgtg gcgcaggggc cgttgacccg gacgcagatc
    12241 ggcgcgctga ccgggctgtc caagcccacc gcttcgcagt tgctggggcg gctggaggcg
    12301 gccgggctgg tgcgtacgac gggcaacgtc accggacggc cggggccgaa cgcccagttg
    12361 tacgaggtga acccggacgc cgcctacgtg gccgcgctcg ccgtcgacca gtgtgggatc
    12421 accgccgcgg tcgccgacgt caccgggcgc gtgctcggtg aggagcgggt cggtacggag
    12481 gccgtggagg aggacgcgcc gcccaggacg gcgcagctgg tggcctcggc cgtggacggg
    12541 gcgctggaca aggccgggct gacgcgggag cgcctgcacg gggcggtgat cgggacgccc
    12601 ggcgcgctcg acccgcagac cggtgtgctg cggtacgcgc cccacctgcc gggctggcac
    12661 gcgcgggcgc tcaaggacga gctggccggc gtgctgggtg taccgatcgt gatcgagaac
    12721 gatgtgaacc tggcggcggt cgccgagcag cacgacggcg ccgcgcagga cttcgacgat
    12781 ttcgtgctgg tgtgggccga cgagggggtc ggcgcggcca tcgtgctcgg tggtcaggtg
    12841 ctgcgcggag ccaccggagg cgcgggcgag atcggctaca tgccgctgcc gggggcgccg
    12901 ctcgcgcgcg gcggcgaacg cgacgcggcc cggccggacg ccggcggggg cttccagcgt
    12961 ctcgtcggct cgccgagcat cgtggagctg gcgcaggagt acggcgcggc ggatgtccgt
    13021 acggtcgacg aggcgctgga cgacgaccgg gtgcgcgccg aggtggcccg gcgcctggcg
    13081 accgggctgg cggccgtggt cgccgtcgtg gacccccggc tggtggtcct ctccggggaa
    13141 gtcgcgcagg tgggtggaga accgctgcgg gagctggtcg aggaggaatt cacggggctc
    13201 gcgctgccgc ggccggagat tcgcatcagc aacatcgagg ggaatccgat tctcaccggc
    13261 gcgctgcaca cggcactcgc cgaggcacgt aacgccgtgt tcgacacggc gtgatgaggc
    13321 ggtgcggagg gccggtgacg gcccggaccg acgctacggc ccccaccggt cgattatccg
    13381 gcggtcagcg catctgccag gccgagaaca ccagcatcat gaacccgaag ggctgcccgc
    13441 gtgccgtacg cgcccgggcc atcaccggcg tcgagaactc cgtacgcccc cgcacccgca
    13501 ccactccctg ccatcacccc tgccgtaaag gaagttcgcc atgccgcgtc cgcgcatgcg
    13561 catctgcctg tcagcggcgc tcgccggggc cggtctgatt ctttcgggct gcgccaatcc
    13621 gagcgtcggc agcgatcgcg acgacccgtc ccagcccgtc acgctgaagt tctggcacgg
    13681 ctggtccaat ccggccgagg tgaaggcggt cgacgacagc atctcccgtt tcgagaaact
    13741 gcatccgaac atcaaggtga agacggtcaa caacgtcacc gacgagaccg tgaaccaggc
    13801 gctgcgggcc ggcggggacg acgcgccgga cgtcgtgtcg tcgttcacca ccaacaacgt
    13861 ggggcagtac tgctcatcgg gtatgtgggt ggatctcgat ccgttcatga agaagacggg
    13921 tgtggagaag gcgaaggtct ttcccaagac gtttcttgat tacacgagtt atcaggggaa
    13981 gcagtgcgcc ctgccgctgc tcgcggacgc gtacgggctg tattacaaca aggacgcgtt
    14041 caaggaggcc ggtatcgagc ggccgccgcg gaccatgtcc gagttcaagc gggacgcggc
    14101 caagctcacg aagcgcaagc cggacgggtc gtacgagcgc gccggcttca tgcccaactt
    14161 ccggctgtac cagaacagtc cggaccggct tttcgcgcag tggggtccga cgtacttcga
    14221 caagaagggc aaggcgcagc tcgccaagga cccgcggacg aaacagttcc tggccacgca
    14281 gcgggagttg atgggcgcgc agggcggtta tgccgccctg gagaagttcc gtacgacgtt
    14341 cggggacgag atgtcgccgc agagttcctt catgtcgcag aaggcggcca tgcatatgga
    14401 cggtgaatgg cgcgggctga tgctgaagga gggcaaggcg aagttcgact gggggacggc
    14461 gccgctgccg gtgccggacg accaggcgga cacgtacggg cggggttatt tgaccggcac
    14521 cgtcgcgggc atcgcgcaca gcagcaagca ccagaacgcg gcgtgggaac tggtgaggtt
    14581 cctgaccgtg gacacggacc aggtggtgcg gttcgccaac gcgatccaca atgtgccgtc
    14641 cacgttcgcg gcgctcacgt cgccgaagct ggatgccgat ccgtcgttcc gtacgttcat
    14701 cgacatcgcg cgtaatccgc acagccaggc catgccgccg tccatcaacg gcgggcagta
    14761 catcacggcg ttccaggatt tcgcgtacaa cgccgaggcc gggaaggtac cggatctcgg
    14821 caaggggctg cgtgacctcg atgcccagat agacgccgac aacctccagt ccgtgaactg
    14881 acggagtcct gccatgtccc tcgtcgaatc ccccgaacgc ccggcggcca ccgcgccgcg
    14941 cccgaaagct cccgcactgc gccgcaaaca cctcgggcag cggctgcgca ccctcggttt
    15001 cctctccccc tggctggtcg gtttcagcgt cttcttcggc tatccgctgc tcgccaccgt
    15061 ctatttctcg ttcatgcact acaaccagat ccagcagccg tccttcgtcg gcctgcggaa
    15121 ctggaagtac gtcttcacgc agatgccgct gttcgggccc gcgctgtgga acacgctgtg
    15181 gctggtcgtg gtgatggtcg cgctgcgcgt ggtcttcggg ctgggcatcg gcctgctcgt
    15241 cacgaagatc aagtcggggg tcggcttctt ccgtaccgcc ttctacctgc cgtatctcgc
    15301 accgccggtc gccgcgacgg tcgccttcgt cttcctgctc aaccccggca ccgggccggt
    15361 caacgagatc ctggaggcgg tcggcatccc ggcgcccggc tggttcaacg acgcggcgtg
    15421 ggccaaaccg tcgctggtca tgctctccct ctggggcatc ggcgacctga tggtgatctt
    15481 catggcggcg ctgctggacg taccgaagga acagtacgag gccgccgagc tggacggggc
    15541 cggcgcctgg gcgagattcc ggtacgtgac gtggccgtcg atcacgccga tcgtgctgtt
    15601 cgcggtggtc accggggtgg tacagaccat gcagtactac acgcaggcgc tggtcgccgg
    15661 gaagctggcc tccggcgtca ccatcgggcc cggcacggtc atccagcccg gctacccgga
    15721 ccactccacc ctcaccgtgc cgcagctcgt ctactcgctc ggcttccaga acttcaacac
    15781 cggcgcggcg tgcgtgctct cgctcgtgct cttcgtgatc gccatggccg tcaccaccct
    15841 gctgatgcgc aagcgcgccg gcctgctccc ggcggaggac tgaaccgaca tgaccacgac
    15901 gacactgaga gcgggcagcg cccccgcgcg caccggcacc accgaccggg gccccgccgc
    15961 gtcccgcgcc cgccgcaagc ggctactgca ctggatagcg gtgcattccg tcgccgtcgc
    16021 ggccgcgctg ttcttcgtcc tgccgttcgt attcgtcttc ctgacctccg tcatgagcga
    16081 cgaccaggcc atgagcggcg aactgtggcc gcacgaatgg aactggtcga attacgcgac
    16141 ggtgttcgcc acccccggct tcctggactg gtggcggaac tcgctgatgt acgcggggct
    16201 gggcacgctg ttcaccgtcg gttcggcgat accggtggcg tacgcgctcg ccaagttccg
    16261 tttccggggc cggcgtaccg cgatgctgct ggtgatttcg acgatgatgc tgccgccgca
    16321 ggtcatcgtg atccccatgt acctggtgtg ggcgcagcag ctgcacctgt ccgggtcgct
    16381 gtggccgctc atcattccga tggcgttcgg tgacgcgtac tccatcttcc tgctgcggca
    16441 gttcctgctc accattccgc aggaatacat cgagtcggcg aaggtggacg gctgcggcga
    16501 ggtccgtacg ctgctgcgca tcgtcgtccc gatggcaaag ccgggcatcg ccgcggtggc
    16561 gctgttccag ttcttctact gctggaacga ctatttcgga ccgcagatct acgccgcgca
    16621 gaacccggcc gcctggacgt tgagttacgg cctcgaatcg ttcaagagcg cgcacaacgt
    16681 caactggaac ctgaccatgg cggcgacgct gctcgtcatg gcccccgtca tcatcgtgtt
    16741 cttcttcgcg cagaaagcct ttgtcgaagg cgtcacgctc accggagtga agggctga
//
