LOCUS       reptomyces_RBGC_274072 16852 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_274072
VERSION     Streptomyces_RBGC_274072
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000721105.1
  ORGANISM  GCF_000721105.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..1647)
                     /protein_domains="PF16499"
                     /protein_domains="PF00652"
                     /protein_domains="PF17801"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910797"
                     /pseudo=False
                     /translation="VPGRSGRRLLRLLAAAALTVTASLTVAVHSNASAAPGSPALTPPL
                     GWNSWNSFGCGVTEAQIRQAADAMVSSGMREAGYRYVVVDDCWFDPQRDAAGNLRANPA
                     KFPSGMKALGDYIHNKGLKFGIYQVPGERTCAQTSGAYPGSTGSRGHETQDAATFASWG
                     VDYLKYDWCSSSGTRDEQVARFTLMRDALRATGRPIVYSINPNSFHAITGATYNWGEVA
                     DLWRTTEDLLDIWQNGNTNSYPMGVGNVLDVTAPLAAQSGPGHWNDPDMLVVGRPGLSL
                     TESRSHSALWALLGAPLMAGNDIRTMSADVSAILRNPRLLAVNQDPRGAGGRRVRDDGG
                     TEVFAKPLSDGSVAVGLFNRGGGTATVATTAAQVGLSGGPFTLTDLWTGGTSSTSGQIS
                     ASVPAHGVAVFRVSGGSPSAATTSRLRGTGSGRCVDVDNASTASGATVLLWDCHTAANQ
                     LWTTWAGGEIRVFGDKCLDAYDQGTADGTRVITWPCNGQNNQKWSVGSDGSVRNVHSGL
                     CLDADREGTANGTPLVLWTCDGRAGQKWTRA*"
     CDS             2052..3700
                     /protein_domains="PF04616"
                     /protein_domains="PF17851"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910798"
                     /pseudo=False
                     /translation="MDMSCSRQPTGRRRALAAGTGLVTGAFLSLTGASRTAAAAPGPES
                     PLAAAPAYTNPVIWQDFADIDIIRVGATYYTSASTMHYSPGAPVLRSYDLVNWEIAGHS
                     VPVLDFGAKYDLNGARGYVRGVWASSLAYRPGNRTFYWLGQIDFARTYIYTATDVEGPW
                     SRLTTISTPYYDAGLLVDTDDTLYVAYGNTAISVAQLSPDGRNQVRTQQVFTTPSSVGT
                     LEGSRFYKINGQYYIFLTRPANGQYILKSSSGPFGPYTMRQVLLDLRGPIPGGGVPHQG
                     GLVQTQSGAWYYMAFVDAYPGGRMPVLAPVTWTPDGWPVVQLVNGAWGTSYPGPTIPTP
                     PRQVTPMTGVDTFDGTRLKPRWEWNHNPDNTKWSVNNGLTLRTATVTNDLYGARNTLTH
                     RIQGPTSTATALLDHSAMRDGDRAGLALLRDSSAWIGVKRDGGVTRVVMVNGLTMDGNW
                     NTTDTGTEVASAPVSGARVWLRASADIRPGAVRPGTFSYSTDGTDFTRLGPAFSLGNDW
                     RFFMGYRFALFNHATQALGGAVRVPRFELSTP*"
     CDS             3754..5780
                     /protein_domains="PF00331"
                     /protein_domains="PF03664"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910799"
                     /pseudo=False
                     /translation="MNPLTRLGRRRASVLSLLAVGALVTPGAATAAPDAPDAVRASTLG
                     AQAAQSGRYFGTAVAAGRLGDGTYTGILGREFNSVTPENEMKWDATERSRGQFTFGAAD
                     QIVNGATARGQRVRGHTLVWHSQLPGWVSAIRDANTLRGVMNNHITTVMNRYKGRIHSW
                     DVVNEAFADGGSGQLRSSVFRDVLGNGFLEEAFRTARTADPSAKLCYNDYNIENWSDAK
                     TQGVYRMVRDFKARGVPIDCVGFQSHFGAGGPPSSFQTTLSNFAALGVDVQITELDIAQ
                     APPNAYANTVRACMNVARCTGITVWGIRDSDSWRSGENPLLFDRNGNKKPAYQSALTAL
                     GGTTAAQRADARSAGSAAALPSSFRWSSSGPLIAPKPDATHNIAGIKDPSVVYYNGKYH
                     VFASTASSAGYNLVYLSFSDWSQAGSATHHYLDRTAIGTGYRAAPQVFYNTQQRLWYLV
                     YQTGNASYSTNADISNPNGWSAPRNFYASMPDIIKQNIGNGYWVDMWVICDSANCYLFS
                     SDDNGHLYRSQTTVGQFPNGFTNTVIAAQDSAHALFEASNVYKVQGSNQYLLLVEAIGS
                     DGRRYFRSWTATSLAGSWTQLAASEGNPFARSNNVTFPSGAWTRDISHGEMIRAGYDQT
                     LTIPACKLQYLYQGMNPNASGDYNLLPWRLGLLTQTNSTC*"
     CDS             complement(5857..6761)
                     /protein_domains="PF00561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910800"
                     /pseudo=False
                     /translation="MPATTAHQLHRITTNGVQLNVAIAGDGPAVLLLHGFPHTWQLWSG
                     IMGRLAGQYRVIAPDLRGFGASTRAAEGYDAGTLAADAEGLLDALGEPSAAVVGIDAGT
                     APAVLLALRRPGLVRRLVVMEGLLGRLPGAEHVTAGGAPWWFGFHAVPGLAETVVAGNE
                     ASYIDWFLDSGTLGRGVPDDIRAAFVHAFTGSEALRCAFSYYRALPTSAQQIQDAVATA
                     RLTMPTMAVGSHPVGTGLERQLRPIADDLVGHHLQDCGHIIPLDRPDALFALLAPFLSA
                     DLPRCHQGEQSAAHDGTSVF*"
     CDS             6975..7273
                     /protein_domains="PF01638"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910801"
                     /pseudo=False
                     /translation="MAVKTLADAAPDEVRFAELRRRMPGVSQKMLSVTLRSLTRDGLVS
                     RRVEPTVPPRVFYRLTGLGLSLEVALAGLRTWAEEHMTAINRANEAADQEVDEG*"
     CDS             complement(7685..8781)
                     /protein_domains="PF03824"
                     /protein_domains="TIGR00802"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910802"
                     /pseudo=False
                     /translation="VTTTTITAGRWSRAERLRITGIVGVIAALHVVGWSLYLFYAGGPA
                     GAGAFAGAGTLAYTLGMRHAFDADHIAAIDDTTRLMMQRGRRPVGVGFFFAMGHSTVVL
                     ALALVVALAAGAAGSGIGTFRHVGGLVSQIVAMLFLLLVAVLNLMVLTGIVALWRRMTQ
                     GRLDPNELEQQLHNRGMMNRLLGHRARGLIRSSWHMYPVGILFGLGLETASEITLLSLS
                     ASAATHGSGLPTLAVLSLPLLFAAGMSAFDTADSMLMTRLYTWAYRSPARRLYYNITTT
                     GMTVAVAAFIASVYIAGLVTDATGARGLLSTYASLADHFELLGYIVVAIFTVSWLIAAA
                     IWRYRGLAEKYGNRRDAADETPHRP*"
     CDS             complement(8932..9239)
                     /protein_domains="PF02211"
                     /protein_domains="TIGR03889"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910803"
                     /pseudo=False
                     /translation="MEATAPTPPLHDTCVTDMNAPTFDADWQRRAFGVAVALSEFGHYP
                     WDAFQQRLIDAIGAWEAASATEQGSWQYYEHWLAALERVLVDHDLVAEDEMRALLGA*"
     CDS             complement(9273..9895)
                     /protein_domains="PF02979"
                     /protein_domains="TIGR01323"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910804"
                     /pseudo=False
                     /translation="VTVQFGYPEDREARSAARVRALEALLIEKGVITDATVDKVLGYFE
                     ADMTPLNGAKIVARAWTDAEFAERLVKDTPAAVAELDLPVGMDGAEGEHLQAVANTPGV
                     HNLVICTLCSCFPWPVLGLPPYWYKDPTFRARAAREPRVVLKETGLDLDPSVELRVWDS
                     SGHSRWFVVPQRPAGTDGMTEEQLAALVTTESMIGIAEVPSPAA*"
     CDS             complement(9893..10644)
                     /protein_domains="PF02211"
                     /protein_domains="TIGR03888"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910805"
                     /pseudo=False
                     /translation="MKLQHHLGGLENLGPVTYEPRVFVEDWEQRVFGIHVAMMGLSAHL
                     GDAVPQYPIEDVPTAFSSVWTWADLRKGAEAMHPFAYFQYRYYEKWLGGIGGFFVSQGY
                     ITEEELEAKAAEYLQDPGLDLPEGGDERIDDQVIRYLREGDSPRQGPATSPAFAVGDLV
                     TVKDVPPTEHTRLPGNLRGRTGTVERVFEGDYGYFCSTGPDGIGEPMPVYAVRFEPTDI
                     WGELAEPGAVLYGELYQAYLTHAMEEQQ*"
     CDS             complement(10642..11159)
                     /protein_domains="PF06496"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910806"
                     /pseudo=False
                     /translation="MRQLDALSISIGVLGGAATLMTATVLTIPVWVIFIAWASFFILGA
                     GTDGMVRSIASNLTGIVIASLTLLVIHALGGGTTVAAVTVGVGSAAMVQASKISLLSKL
                     PAIVWGFASTVGTVAATGHDITTTSISNPALVAALAMVLGAAFGIASEYWGAAMTARPA
                     AEPTPEGQS*"
     CDS             complement(11330..11472)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MVAGTYWCLTAPKPTQSEPRVLTVMRPSVGPYVVAAGDGEARIST
                     SN"
     CDS             complement(11467..11618)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MFGPVLILTLQPPVASSTGLGGFFCVDITKPQPSIPDIIYSAIVN
                     LHETW"
     CDS             11808..12874
                     /protein_domains="PF12833"
                     /protein_domains="PF01965"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910807"
                     /pseudo=False
                     /translation="MNRSIAGADRGTERTMVFVLYDKVTLQDVAAPLEIFARANDFGAR
                     YRVLLVSPTGQPVGTTAFTRLSADFPVTDAPDSIDTLLVPGGVPADFTFASGTHDIPEE
                     LTPDTVPEALAMVQELAPRASRIASVCTGAFVLAALGMLDGRRATTHWAHCARLAREYP
                     RIEVDPDALFVQDGSFVTGAGISAGTDMALAIVENDYGTDVARRVARWMVVFLQRPGGQ
                     AQFSVWSEAGAPTTRGLRQVLDSVVLEPAADHSAASMAARAAVSERHLARMFRDEVRMT
                     PARYVEQTRLEAAKLLLVTGDESQESVARRVGFGSPETMRRIFRRNLGVSPGGYRSRFR
                     TTGIDRQEPESDQDA*"
     CDS             complement(13445..14118)
                     /protein_domains="PF04167"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910808"
                     /pseudo=False
                     /translation="VHTFETGQTVVRRDVHRCGRVWSEHALRIVADTSEALVAACPPGA
                     ETRWPALYVKARADGVRAVRTEAFDAMASGVWELAAAVWQETELLLWKPPAAWFSVNAF
                     FTIGGLRNWYVNFEHPTVRTGDGFDTFDLAVDLVVAPDLSSWQWKDEDEYAHVRRLGIV
                     TDTEHRAVDAARDQALAMLEERSGPFADADSWSAWRWNPAWPAPTLPRPVAAGQKVAPT
                     GG*"
     CDS             complement(14891..15282)
                     /protein_domains="PF13411"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910809"
                     /pseudo=False
                     /translation="VLIGELAAQTGTTTRALRYYEEQGLLESDRTPSGYRVYSPHAVTR
                     VRNVRDLLASGFTIDNVKSFVRYLDTDLPEVFEYSPSCADGYGVGARRVAELGEKIASL
                     TRMRDILVHRMPWLASPNDAAQKEAA*"
     CDS             complement(15329..16395)
                     /protein_domains="PF16884"
                     /protein_domains="PF00107"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3910810"
                     /pseudo=False
                     /translation="MLSVSGMKPFTKSATPPALSSLPSSGLEVRLASRPVGLPTLDHFE
                     IVEAPVPVPAPGQVLVRNLFMSLDPGMLMQIAGGSPLPMRPYAVGEVMYGDAIGEVVAS
                     ADPSLAEGELVVHRLGWREYAVAEAGGFRRVDKTAYPSPSLHLGFGLVAYVGLMDAAGL
                     RPGDTVFVSSAAGATGSMAGQIARLKGAGRVIGSAGSADKVAYLTGKLGFDAAFDYHDG
                     PVLDRLREAAPDGIDVYFDNVGGEQLRAAVEVMNVQGRIAVCGALNRQSTGRPDEGPGD
                     LLNVLGKRLTIRGFTLWDHLNRAVEFGEQFRDWLREGSIVYDETVIDGLASAPQALLDL
                     VHGRYTGKTVVRLMS*"
     CDS             16626..16852
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_3910811"
                     /pseudo=False
                     /translation="VITGLFDGFCSTDDPAPWLGKRLRTEEAVALMKELGEDHSTGQEE
                     GGHGVPDKAYSSRGLRAKTDSSAGSGGVGE*"
ORIGIN
        1 ttacgcacgg gtccacttct ggccggcccg gccgtcgcag gtccacagga ccagcggggt
       61 gccgttggcg gtaccctccc ggtcggcgtc gaggcacagt ccggagtgga cgttgcggac
      121 cgacccgtcg gagccgacac tccacttctg gttgttctga ccgttgcagg gccaggtgat
      181 cacccgtgtg ccgtcggcgg tgccctggtc gtaggcgtcc aggcacttgt cgccgaagac
      241 acggatctcg ccgccggccc acgtggtcca cagctggttg gctgccgtgt ggcagtccca
      301 gagcagcacc gtggccccgg aggcggtaga ggcgttgtcc acgtccacgc agcggcccga
      361 accggtgccg cgcaagcgag aggtggtggc ggccgacggg ctgcccccgc tcacccggaa
      421 cacggccacg ccgtgcgcgg ggacgctcgc cgagatctgc cccgacgtgc tcgacgtgcc
      481 gccggtccac aagtcggtga gggtgaacgg gccgccggac agcccgactt gtgcggccgt
      541 ggtcgcgacc gtcgccgtgc cgccgccccg gttgaacagg cccaccgcga ccgagccgtc
      601 ggagaggggc ttggcgaaca cctcggtgcc gccgtcgtcg cgcaccctgc gcccgcccgc
      661 gccccgcgga tcctggttca ccgccagcag ccgcgggttg cgcaggatcg cgctcacgtc
      721 ggcggacatg gtgcggatgt cgttgccggc catgagcggg gcacccagca gtgcccacag
      781 ggcggagtgg gagcgggact cggtcagtga caggccggga cggcccacga ccagcatgtc
      841 cgggtcgttc cagtgccccg ggcccgactg cgcggccagc ggtgcggtga cgtccaggac
      901 attgccgacg cccatcggat aactgttggt gttgccgttc tgccagatgt cgagcaggtc
      961 ctcggtcgtc cgccacaggt cggcgacctc gccccagttg tacgtggcgc cggtgatggc
     1021 gtggaagctg ttggggttga tgctgtagac gatcggccgc ccggtggcgc gcagggcgtc
     1081 gcgcatgagt gtgaaccgcg cgacctgttc gtcgcgggta ccgctggagg agcaccagtc
     1141 gtacttgagg tagtcgacgc cccacgacgc gaacgtggcg gcgtcctggg tctcgtggcc
     1201 cctgctgccc gtcgacccgg gataggcgcc gctggtctgc gcgcaggtgc gttcgcccgg
     1261 tacctggtag atgccgaatt tcaggccctt gttgtggatg tagtccccga gggccttcat
     1321 cccgctcggg aacttggccg gattggcccg caggttgccc gcggcgtcgc gttgcgggtc
     1381 gaaccagcag tcgtcgacca ccacgtaccg gtagccggcc tcccgcatgc ccgaggacac
     1441 catcgcgtcg gcggcctgac ggatctgagc ctcggtgacc ccgcatccga agctgttcca
     1501 gctgttccag cccagcggcg gagtgagggc cggactgccg ggcgcggccg aagcgttgga
     1561 gtggactgcg accgtgaggg acgcggtgac cgtcagtgcg gcggccgcca agagcctgag
     1621 cagtcgtctg cctgatcgtc ctggcaccgt gggctccttt cgaggtgggc accgcaggtc
     1681 ggacacctac ggccctcgcc gaggcaaaca gcggatgact gccgacctgc cgtcgactta
     1741 tgtcacgggc atgacatatc cgatcgttcg aaatttcggt ctactttcgg atcgccaaca
     1801 tcacggatac tagggagttc ccctcgcttg tcaattcccc cacccccgat cacgctccat
     1861 ccgcaccact cgaaccttcg atcaacaacg aaatctttcg atgtcatcaa cgaatcatgc
     1921 gagacgtatt gacgggatcc ctcaaccacc taccatcctg aatgcccacc agtcgattac
     1981 cgctcgccat ctcgaacatc gcgggaatcc accaccctcc gaagcacgtc acccgcagag
     2041 ggagcgacac atggacatgt catgctctcg tcaacctacg gggcgccgcc gggccctggc
     2101 cgctggcact ggcctcgtca ccggtgcctt cctgtctctg accggagcct cccggaccgc
     2161 cgcggccgct ccgggtccgg agtcgcccct cgcggcggct cccgcgtaca cgaacccggt
     2221 gatctggcag gatttcgcgg acatcgacat catccgggtc ggcgccacct attacacctc
     2281 cgcctcgacg atgcactact cgccgggcgc gcccgtcctg cgttcgtacg acctggtgaa
     2341 ctgggagatc gccggtcact cggtgcccgt actcgacttc ggcgccaagt acgacctgaa
     2401 cggtgcccgt ggctacgtgc gcggggtctg ggcgtcgtca ctggcctacc ggcccggcaa
     2461 caggaccttc tactggctcg gccagatcga cttcgcccgg acctacatct acaccgcgac
     2521 cgacgtcgag ggtccgtgga gccgactcac gacgatcagc acgccctact acgacgcggg
     2581 actgctcgtc gacaccgacg acaccctcta cgtggcgtac gggaacaccg ccatcagcgt
     2641 ggcccagctc tcgccggacg ggcgcaacca ggtacgcacg cagcaggtct tcaccacacc
     2701 ctcgagcgtc ggcacgctcg agggctcccg cttctacaag atcaacgggc agtactacat
     2761 cttcctgacc cgccccgcga acgggcagta cattctgaag tcgtccagcg gccccttcgg
     2821 tccgtacacg atgcggcagg tccttctcga cctgcgcggg ccgatccccg gcggcggcgt
     2881 cccgcaccag ggcgggctgg tgcagacgca gagtggcgcc tggtactaca tggccttcgt
     2941 ggacgcgtac cccggtggtc ggatgcctgt cctcgcgccg gtcacctgga ctccggacgg
     3001 ctggcccgtc gtgcaactgg tgaacggcgc ctggggcacc tcgtatcccg gcccgaccat
     3061 ccccactcca cctcgccagg tcacccccat gaccggcgtc gacaccttcg acggcacgcg
     3121 cctcaagccg aggtgggagt ggaaccacaa cccggacaac accaagtggt ccgtcaacaa
     3181 cggactgacc ctgcggaccg cgaccgtcac caacgacctg tacggggccc gcaacaccct
     3241 cacgcaccgc atccagggtc ccacctccac cgctaccgcc ctgctcgacc actcggcgat
     3301 gcgggacggc gaccgggccg gactcgcgct gctgcgtgac tcctcggcct ggatcggcgt
     3361 caagcgcgac ggcggagtga cacgggtggt gatggtcaac ggcctcacca tggacggcaa
     3421 ctggaacacc accgacaccg gcaccgaggt cgcgagcgcc cccgtctccg gcgcccgcgt
     3481 ctggctccgc gcgagcgcgg acatccgccc cggcgcggtc cgccccggca ccttctccta
     3541 cagcaccgac ggcaccgact tcacccgcct cgggcccgcc ttctccctgg gcaacgactg
     3601 gcggttcttc atgggctacc gattcgccct cttcaaccac gccacgcagg cgctcggcgg
     3661 cgcggtccgc gtcccgcggt tcgagctgtc gacgccctga tccgatccac cgaccgcacc
     3721 acccaacccc ccgccaaccg tagaggagaa ccatgaaccc gctcacgcgg ctcggccgtc
     3781 gccgagcatc ggtgttatcg ctgctggccg tcggcgccct ggtgacgccc ggcgccgcga
     3841 ccgccgcacc cgacgcgccc gacgccgtcc gggcctccac tctcggggcc caagcagccc
     3901 agtccggacg gtacttcggc accgctgtgg cagccggaag gctcggcgac ggaacgtaca
     3961 ccggcatcct ggggcgcgag ttcaactcgg tcacacccga gaacgagatg aagtgggacg
     4021 cgaccgagcg gtcccgcgga cagttcacct tcggcgccgc cgaccagatc gtgaacggcg
     4081 ccacggcccg cggtcagcgc gtgcggggcc acacgctggt gtggcactcc caactgcccg
     4141 gctgggtcag cgccatcagg gacgcgaaca cgctgcgtgg cgtgatgaac aaccacatca
     4201 ccacggtgat gaaccgctac aagggccgga tccactcctg ggacgtggtc aacgaggcct
     4261 tcgccgacgg cggcagcggc cagctgcgca gctccgtctt ccgggacgtg ctgggcaacg
     4321 gcttcctcga ggaggcgttc cgcacggccc ggacggccga tccatcggcc aagctctgct
     4381 acaacgacta caacatcgag aactggagcg acgccaaaac ccagggcgtc taccgcatgg
     4441 tgcgcgactt caaggcgcgc ggcgtgccca tcgactgcgt cggcttccag tcccacttcg
     4501 gcgccggcgg cccgccgtcg agcttccaga cgacgctgtc gaacttcgcc gctctcggcg
     4561 tggacgtcca gatcaccgag ctggacatcg cgcaggcacc gccgaacgcg tacgccaaca
     4621 cggtcagggc ctgtatgaat gtggcgcgct gcaccggcat caccgtgtgg ggcatccggg
     4681 acagcgactc ctggcgcagc ggagagaacc cgttgctgtt cgaccgcaac ggcaacaaga
     4741 agcccgccta tcagtcggcg ctcaccgcgc tggggggcac gaccgcggca cagcgggcgg
     4801 acgcccgttc ggccgggtcc gccgccgcac tcccctcctc cttccgctgg agctcgagcg
     4861 gcccgctgat cgccccgaag ccggacgcga cccacaacat cgccgggatc aaggacccgt
     4921 cggtcgtcta ctacaacggc aagtaccacg tgttcgccag caccgcgagc tccgccgggt
     4981 acaacctcgt gtacctgagc ttcagtgact ggtcacaggc cgggtcggcc acccaccact
     5041 acctggaccg caccgccatc ggcaccggat accgggccgc gccacaggtc ttctacaaca
     5101 cccagcagcg cctgtggtac ctcgtctacc agaccggcaa cgcgtcctac tccaccaacg
     5161 ccgacatcag caacccgaac gggtggagcg caccgcgcaa cttctacgcg tcgatgcccg
     5221 acatcatcaa gcagaacatc ggcaacggtt actgggtcga catgtgggtg atctgcgaca
     5281 gcgccaactg ctacctgttc tcctccgacg acaacggaca cctgtaccgc tcgcagacga
     5341 ccgtcggcca gttccccaac ggcttcacca acaccgtcat cgcggcccag gactccgcac
     5401 acgccctctt cgaggcaagc aacgtgtaca aggtccaggg ctccaaccag tacctgctcc
     5461 tcgtcgaggc catcggatcg gacggccgac gctacttccg ctcctggacg gcaaccagcc
     5521 tcgccggctc ctggacgcaa ctggccgcgt ccgagggcaa ccccttcgcc aggtcgaaca
     5581 acgtcacctt cccgtccgga gcctggacca gggacatcag ccacggcgag atgatccgcg
     5641 ccggctacga ccagacactc accatccccg cctgcaaact ccagtatctc taccaaggca
     5701 tgaaccccaa cgcgagcggt gactacaacc tcctcccctg gcggctcggc ctcctcaccc
     5761 agaccaactc gacctgctga ccgtccgtgt cgtgggggag cgctcccgat ggagcgctcc
     5821 cccacactca ccgccgaccg tacgacgcat ccgtgtcaga agaccgaggt accgtcatgc
     5881 gccgcggact gctcgccttg gtggcagcgc ggcagatcgg cggagaggaa gggagcaagg
     5941 agcgcgaaca acgcgtcggg gcggtcaagg gggatgatgt ggccgcagtc ctggagatgg
     6001 tgtccgacca ggtcatcggc gatgggccgg agttggcgtt cgagaccggt gccgacgggg
     6061 tgagagccga cggccatggt gggcatcgtc agccgagccg tcgcgacggc gtcctgtatc
     6121 tgctgcgcgc tggtgggcag ggcccggtaa taggagaacg cacaacgcag ggcctcgctc
     6181 ccggtgaacg cgtggacgaa ggccgcacgg atgtcgtcgg gtactcctcg cccgagcgtc
     6241 cccgagtcga ggaaccagtc gatgtacgag gcctcgttgc cggcgacgac ggtctcggcg
     6301 aggccgggga cggcgtggaa gccgaaccac cacggggcgc cgcccgcggt gacgtgttct
     6361 gctccgggca ggcggccgag cagtccctcc atcacgacca ggcgccggac gaggccgggg
     6421 cggcgcagcg cgagcaggac ggcgggggcg gtgcccgcgt cgatgccgac cactgctgcc
     6481 gagggctcgc cgagtgcgtc gagcagccct tcggcgtcgg cggcgagggt gcccgcgtcg
     6541 taaccctcgg cggctcgtgt actggcaccg aagcctcgca ggtccggggc gatgacccgg
     6601 tactgcccgg ccagtcggcc catgatgccg ctccagagtt gccaggtgtg cgggaagccg
     6661 tgcagcagga gaaccgcggg tccgtccccg gcgatggcga cgttgagttg gacgccgttc
     6721 gtcgtgatgc ggtgcagttg gtgtgcggtg gtggcgggca tgacgaactc ctacggctag
     6781 ttactattgg tgaccacaga acgataggta actgtccgac cgctgcctag aaggcacttt
     6841 cagggaaggt ggtgagccac aggtgaccac ccgaggagcc cggaccgccg gtcgcggggc
     6901 gcgcggcgat ctgttcgatc cccggtgccc gacgcggcag ttgctggacc gcgtaggtac
     6961 gaagtggacg tccatggccg tcaagacgct cgccgatgcc gcaccggacg aggtgcgctt
     7021 cgcggagctg agacgccgga tgcccggcgt ctcgcagaag atgctgtccg tgacgctgcg
     7081 aagcctgacc cgcgacgggc tggtgtcgcg ccgggtcgaa ccgaccgtgc cgccgcgggt
     7141 cttctaccga ctcaccggac tcgggctgtc tctggaagtc gcgcttgcgg ggctgcggac
     7201 ctgggcggag gagcacatga ccgcgatcaa ccgcgccaac gaagccgccg accaggaggt
     7261 cgatgagggg tagacagtcc gcttccgcgc tcagtgctgg tgctcgggta ctcgatgtag
     7321 ccggcgtcgc cgcgcggtcc tcggcgcggc acggacgacc tgcgcgaatg aagccggttc
     7381 agcgggccgc cggcgcggtc gtcggctcag cggtgggtga cgcactgggc ggccccttcg
     7441 agttcggtcc ccagggacgt tctccgcgcg ggaactcgcg cctggtgccg gtggcgagat
     7501 gtgcggaggc ggtggctggg gccccggcga ggtcactggc gacacagcca ccatggacgc
     7561 ggcccgccgc attgcgcctg ccgctggcgt gctacaccca tgaacaccgg ctcgtcccgc
     7621 gggccggctt cgggcggtgg gagcggaagc ggtgtgcccc acacatgacg ctgcctcaga
     7681 cagtcagggc cggtggggtg tctcatcggc ggcatctcgc cggttgccgt acttctcggc
     7741 gagtccgcgg tagcgccaga tggcggcggc gatgagccag gagaccgtga agatggcgac
     7801 cacgatgtag ccgagcagtt cgaagtggtc ggcgagggag gcgtaggtac tgaggagtcc
     7861 cctggccccg gtggcgtcgg tgacgagtcc cgcgatgtag acgctggcga tgaacgcggc
     7921 cacggccacg gtcatgccgg tggtggtgat gttgtagtag agcctgcggg cggggctgcg
     7981 gtacgcccac gtgtacaggc gtgtcatcag catgctgtcg gcggtgtcga aggcgctcat
     8041 tcccgcggcg aagagcagcg ggagggagag cactgcgagg gtgggcaggc cggacccgtg
     8101 ggtggcggcg ctggcggaca aggagagcag ggtgatctcg ctggcggtct ccagaccgag
     8161 gccgaagagg atgccgaccg ggtacatgtg ccatgacgaa cggatcagcc cgcgggcgcg
     8221 gtggccgagg aggcggttca tcatgcctcg gttgtgcagc tgctgctcga gctcgttcgg
     8281 gtcgagccgg ccctgcgtca tacgccgcca cagggcaact atgccggtca gcaccatgag
     8341 gttgagcacg gcgacgagca gcaggaacag catggcgacg atctgcgaga ccaggccgcc
     8401 gacatggcgg aaggtgccga tgcccgagcc ggcggcgccc gcggcgagcg cgacgacgag
     8461 ggcgagggcg aggaccacgg tggagtggcc catggcgaag aagaaaccca cgccgacagg
     8521 tctgcgtccg cgttgcatca tcagtctggt ggtgtcgtcg atggcggcga tgtggtcggc
     8581 gtcgaaggcg tgccgcatcc cgagggtgta ggcgagggtt ccggcgccgg cgaaggcccc
     8641 ggcgccggcc gggccgccgg cgtagaagag gtacaggctc cacccgacga cgtgcagggc
     8701 ggcgatgacg ccgacgatgc ccgtgatgcg cagccgttcg gcgcggctcc atcggccggc
     8761 agtgatggtc gttgtggtca cacacacatc cttggcaggg ggcaccgcgc ggtgccgtcg
     8821 tcggcggtga gagggggtgg gccgcacccg ctggtcgtga gccattcgcg ggtgcggccc
     8881 tggcggacgg tatggagcgg acgtcctggt ggtgcgggcg tggaaacggg ttacgccccg
     8941 agcagggcac gcatctcgtc ctcggcgacc agatcgtgat cgaccagtac gcgttcgagc
     9001 gccgcgagcc agtgctcgta gtactgccag ctgccctgct cggtcgcgga ggcggcctcc
     9061 catgcgccga tggcgtcgat gagccgctgc tggaacgcgt cccaggggta gtggccgaac
     9121 tccgacaggg cgacggcgac gccgaacgcc cgccgctgcc agtcggcgtc gaaggtgggc
     9181 gcgttcatgt cggtgacgca ggtgtcatgc aggggcgggg tgggggcggt ggcctccatg
     9241 ggattccctt tctctggtgt ccgggggcgg ctcaggcggc gggtgaagga acctcggcga
     9301 tgccgatcat cgattcggtg gtgaccaggg cggcgagttg ctcctcggtc atgccgtcgg
     9361 ttccggcggg ccgctgcgga acgacgaacc agcgagaatg accgctgctg tcccatacgc
     9421 gcagttcgac ggacgggtcg aggtccaggc cggtctcctt gagcaccaca cggggttccc
     9481 gggcggcgcg ggcgcggaag gtggggtcct tgtaccagta cggcgggagg ccgagcacgg
     9541 gccaggggaa gcaggagcac agggtgcaga tgaccaggtt gtgcacgccg ggggtgttgg
     9601 ccacggcttg caggtgttcg ccttcggcgc cgtccatgcc gacggggagg tcgagttccg
     9661 cgacggcggc cggcgtgtcc ttgacgagtc gttccgcgaa ctccgcgtcg gtccaggcgc
     9721 gggcgacgat cttggctccg ttgagcggcg tcatgtcggc ctcgaagtag ccgagcacct
     9781 tgtcgacggt ggcgtcggtg atcactccct tttcgatgag cagggcttcc aacgccctta
     9841 cacgggcggc gctgcgggct tcgcggtcct cggggtagcc gaactgcacg gtcactgctg
     9901 ttcctccatc gcgtgggtga ggtaggcctg gtagagctcg ccgtagagca cggcaccggg
     9961 ttcggcgagt tctccccaga tgtcggtcgg ttcgaagcgg acggcgtaga cgggcatcgg
    10021 ctcgcctatg ccgtcggggc cggtggagca gaagtagccg tagtcgcctt cgaagacgcg
    10081 ctccacggtg ccggtgcggc cgcgcagatt gcccggcagt cgggtgtgtt cggtgggcgg
    10141 cacgtccttg acggtcacca ggtcaccgac ggcgaaagcc ggggacgtgg ccggcccctg
    10201 gcggggggag tcgccctcac gcaggtagcg gatgacctgg tcgtcgatgc gttcgtcccc
    10261 gccctcgggc aggtcgagtc ccggatcctg gagatattcc gcggccttcg cctccagctc
    10321 ctcctcggtg atgtagccct gggagacgaa gaacccgccg atgccgccga gccacttctc
    10381 gtagtagcgg tactggaagt aggcgaaggg gtgcatggcc tcggcgccct tgcgcaggtc
    10441 cgcccaggtc cagacggagg agaaggcggt gggcacgtcc tcgatcgggt actggggcac
    10501 ggcatcgccg aggtgggcgc tgaggcccat catcgcgacg tggatgccga agacgcgctg
    10561 ctcccagtcc tcgacgaaga cgcggggctc gtaggtgacg gggccgaggt tttccaggcc
    10621 gcccaggtgg tgctgcagct tcatgactgt ccttccgggg tcggctcagc ggccggacgt
    10681 gcggtcatcg cggctcccca gtactccgag gcgatgccga acgccgcgcc caggaccatg
    10741 gccagcgccg cgacgagcgc cgggttgctg atggatgtgg tggtgatgtc gtggccggtg
    10801 gcggccacgg tgcccaccgt ggaggcgaat ccccacacga tggccgggag tttcgagagc
    10861 agggaaatct tcgacgcctg caccatggcg gcgctgccga cacccacggt gacggctgcg
    10921 acggtggtgc caccgcccag cgcgtggatg accagcagtg tcagcgaggc gatgacaatg
    10981 ccggtcaggt tcgaggcgat cgacctcacc atgccgtcgg tgccggcacc gaggatgaag
    11041 aaggaggccc aggcgatgaa gatgacccag acgggaatgg tcaggacggt cgcggtcatc
    11101 agcgtggcgg ctcctccgag tacgccgata ctgattgaca aagcatctag ctggcgcatg
    11161 cctaaaaaca ctcctctgac gccgagttct gacgcccggc ggaattcatg cccgaacgtg
    11221 ggcaggcgtt cattgacccg ctgagggtgg aagagaatgg gaagtgacgg cgcgcgaaag
    11281 cgtagcgcaa ggcccgtcta ttggcgccga attcggtgtt tctgcccttc aattcgacgt
    11341 ggatatccgc gcttctccat cccctgctgc caccacataa ggcccgacag agggcctcat
    11401 gaccgtaagt accctcggtt ccgattgtgt cggctttggc gcggtgagac accaataggt
    11461 tccggctacc atgtttcatg caagttaacg atggctgaat aaatgatgtc cggaattgac
    11521 ggctgcggtt ttgtgatgtc aacgcagaaa aagccgccca ggcctgtcga tgaggccacg
    11581 ggaggctgca aggtcaatat gagcactgga ccaaacaggt cttcgtgcgg ttagtattcc
    11641 gtacccggta tttccgggaa ctcggatccc ggatacccgg ccgggtgatt tgctcggctc
    11701 ccacgttccc gcctggcggg gcaggagcca agggctgcaa cggacacgcg agccacgttt
    11761 tcggacacga gggcaagcct cgcgctcccc tggaggaggt cggagtatga accggagcat
    11821 cgcgggcgcg gaccgcggca ccgaacggac gatggtcttc gtcctgtacg acaaggtcac
    11881 gctgcaggac gtggcggcac cgctggagat cttcgcccgg gccaatgact tcggggcccg
    11941 ctaccgggtg ctgctggtct cgcccacggg gcaaccggtc gggacgaccg cgttcacccg
    12001 gctgagcgcg gactttccag tgaccgacgc tcccgactcc atcgacaccc tcctggtgcc
    12061 gggaggtgta cccgccgact tcaccttcgc ctcgggcacg cacgacatac ctgaagagct
    12121 gaccccggac acggtccccg aggcactggc gatggtccag gaactggcgc cccgggcatc
    12181 acggatcgcc tccgtctgca ccggggcgtt cgtgctggca gccctcggca tgctggacgg
    12241 gcgccgagcg acgacgcact gggcgcactg cgcgcgccta gcgcgggaat acccgcgcat
    12301 cgaggtggat ccggacgccc tcttcgtcca ggacggctcc ttcgtcaccg gtgccggcat
    12361 cagcgcgggc accgacatgg ccctggccat cgtcgagaac gactacggca ccgacgtcgc
    12421 ccgcagggtc gcccggtgga tggtcgtctt cctgcaacgt ccgggcggcc aggcccagtt
    12481 cagcgtctgg tccgaagcgg gcgcccccac cacgcggggc ctgcgccagg tcctggactc
    12541 agtggtcctc gaaccggccg cggaccactc ggctgcctcc atggccgccc gcgccgcggt
    12601 gagcgaacgc cacctggcgc ggatgttccg tgacgaggtg cgcatgacgc cggcccgcta
    12661 cgtggaacag acccggctgg aagcggccaa gcttctcctg gtgaccggcg acgagagcca
    12721 ggagtctgtc gcacggcgtg tcggcttcgg ctccccggag acgatgaggc ggatcttccg
    12781 ccgcaacctc ggagtctcgc cgggcggcta ccgcagccgg ttccgtacca ccggcatcga
    12841 ccgccaggag ccggagtccg accaggatgc ctgatccggt gatgtcgtca gcccgcgcgc
    12901 tccagcgacg gagtcagcct caggcgagca gccccgtcgg ccaccgggag acgaccacac
    12961 ctggtgcggc ccacccgtgc cggacccgtt gtgcctggct gccgccgccg agcggtccgg
    13021 ccagtcagtg ggacgtgcag cggggcttcg gttgacgcaa gggcggttgt cgggcgtagg
    13081 tcgatccgga gggcatggcg cagggccgcg ttcgagtccg tgttcgccgc ccgccggctg
    13141 tccgtcccgt gggtgctctg cccgacggca ccaggcacgg acccgaaacc caccgcagca
    13201 cctgcacctc gcgtcgggcc cgggcccggg cccggaactg ctcatccgcc gcctgcccgg
    13261 cgtgcacggc cttcaccgcc cccgctcccc ctgctccccc tgctccccca ctgcggcgta
    13321 caccgtgccc atcccgccca cgcccagcgc acggccatac gcccgtcgcc gtcagatgag
    13381 atccagccgt gcccccgcct gcccggtccg gtccggcacc ggggcatccc tccgaccaac
    13441 ggttcagccg cccgtcggtg caaccttctg cccggccgcc acgggacgcg gaagggtcgg
    13501 ggcgggccag gccgggttcc accgccaggc cgaccaggag tcggcgtcgg cgaacgggcc
    13561 cgagcgctcc tcgagcatcg cgagggcctg gtcacgggca gcgtccacgg cccggtgctc
    13621 ggtgtcggtg acgatgccga gccgccgcac gtgcgcgtac tcgtcttcgt ccttccactg
    13681 ccagctggac aggtcggggg cgacgaccag gtcgacggcg aggtcgaagg tgtcgaaccc
    13741 gtcgccggtc cggacggtgg ggtgttcgaa gttcacgtac cagttccgca gcccgccgat
    13801 ggtgaagaag gcgttgacgc tgaaccacgc cgcgggcggc ttccacagca gcagctcagt
    13861 ctcctgccac accgcggccg ccagctccca caccccactc gccatcgcgt cgaacgcctc
    13921 ggtgcgcacc gcacggacac cgtccgcacg ggccttgaca tacagggcgg gccagcgggt
    13981 ctccgctccg ggcggacagg ctgccaccaa ggcctcgctc gtgtcggcga cgatgcgcag
    14041 tgcgtgctcg ctccacacgc ggccgcagcg gtgcacgtcg cgtcgtacga ccgtctgtcc
    14101 cgtctcaaag gtgtgcactc gttcctcctt cgccgcagcc gggctgctct gctcgcggag
    14161 cccagcccag cccagcgctg accggacggt ctgggcaagc ccccgttcca gggagcctta
    14221 cccaaaagct ctctcggctt tcctggtcag gtccgccggc ggaagacgcg cggagcgcca
    14281 cactcgattt tcagggccca gggtgatctc ctggcccgcc cctctgccgc ctgaagtagc
    14341 gccggaaacc ccttgaggaa gcaaggactg ttccagacgc ccgtgccgcc agtgagcccg
    14401 gcgaccctcg cggtcatcgt gacgaacggg cgggtgaccg cgccgctcgt cgcgttcgcc
    14461 gggcagcagc ggctgcacgt cgtaaaccgc cagacactgg cggcgtgggc gtccggctca
    14521 cgcccactgt gggagcacct gcgagcggtc ccgcctcccc ggcggcccac tccctcgagc
    14581 tgaccagggg aggaaccacc ggagtcgtcg agcggccctc tggagcttgc cgagccatcc
    14641 gcgcaggtca aatcacacgg gatccacttc gggaacggga gcggtcgagt caggagacgc
    14701 ggccgaagac tgcggcgtgg ccgatgactc tggggccgaa cctgcgcctg gtctgcgtcg
    14761 tcggccaggg ctgttggcgc tctgtgcatt tccccgtccc tcgctcaccc gacggacaga
    14821 catgctcaac tggattcccc atctgcgagc gtttctgatt cggctcgggg cggtcgggga
    14881 gatgctggat caggcggcct ctttctgtgc ggcatcattg ggcgaggcca accagggcat
    14941 ccgatggacg aggatgtcgc gcatccgtgt caggcttgcg atcttctccc ccagctcggc
    15001 cactcgtcgt gcgccgacgc cgtagccgtc ggcgcacgac ggcgagtact cgaagacctc
    15061 gggcagatcg gtgtcgaggt agcgcacgaa ggacttgaca ttgtcgatgg tgaatccgga
    15121 ggcgagcagg tcgcggacgt tgcggacccg ggtgaccgcg tggggactgt agacgcggta
    15181 gcccgacggc gtccggtcgg actccagcaa gccctgttcc tcgtagtagc gcagggcgcg
    15241 ggtcgtggtt cctgtctgcg cggccagttc accgatcaac acgtagctac ctccgggcct
    15301 ttccccaact tggcgtgtac tttgcggtca actcatgagc cgcaccacgg tcttcccggt
    15361 gtaccggccg tggacgagat cgagaagtgc ctggggtgcg ctcgccagcc cgtcgatcac
    15421 cgtttcgtcg tagacgatgg atccctcgcg cagccagtcc cggaactgtt cgccgaactc
    15481 cacggcccgg ttgagatggt cccacagcgt gaagcctcgg atcgtcaggc gtttgcccag
    15541 gacgttcagc aggtccccgg ggccctcgtc ggggcggccg gtactctgcc gattgagggc
    15601 tccgcagacc gcgatgcggc cctgcacgtt catgacctcg acggcggcgc gcagttgctc
    15661 gcctcctacg ttgtcgaagt agacgtcgat gccgtccggg gccgcttcgc gcagccggtc
    15721 gagtaccgga ccgtcgtggt agtcgaatgc cgcgtcgaac ccgagcttgc cggtcaggta
    15781 ggcgaccttg tctgccgaac cggcgctgcc gatgacccgc ccggccccct tgagccgggc
    15841 tatctgacca gccatgctcc ctgtggctcc tgccgcgctg gagacgaaga cggtgtcgcc
    15901 gggccgcagc cctgccgcgt ccatgagccc gacgtaggcg accagcccga aacccagatg
    15961 cagggagggg ctggggtagg ccgtcttgtc cacgcggcgg aacccaccgg cctcggccac
    16021 ggcgtactcc cgccagccga gccgatgcac caccagttct ccctcagcga gcgacggatc
    16081 agccgaggcg accacctcgc cgatggcgtc cccgtacatc acctctccca ccgcgtaggg
    16141 ccgcatcggc agcggggatc caccagcgat ctgcatgagc atgccgggat cgagcgacat
    16201 gaacaggttg cgaaccagta cctggcccgg tgccgggacc gggaccggag cctcgacgat
    16261 ctcgaagtgg tcgagggtgg ggagcccgac gggccgtgag gcgagtcgga cctccaggcc
    16321 tgagctgggc aggctggaaa gagcaggcgg cgttgcgctc ttcgtgaagg gcttcatgcc
    16381 gctgacgcta agcattgacc catgcgtgaa ggtcaaccca tcccgcccat gaagcctcca
    16441 cgacgacccg cgatcgccgg acatccctca ggtggtggcc gggcggcctc tgccacacct
    16501 tcaacaggca actgcctggg cccaagagcg agcctcgccg ttctcacggc tctgtccgcg
    16561 ttttcgtgaa caggcgcact ggcaagcagg gtgctgtgct gaagagttcg aggtcctgga
    16621 ctacgtgatc accggtctgt tcgacggctt ctgcagcact gatgatcccg cgccgtggct
    16681 gggcaagagg ctgcggaccg aggaggctgt cgcgctcatg aaggagctgg gcgaggacca
    16741 ctcgacgggg caagaagagg gaggtcacgg tgtcccggac aaggcctaca gctcgcgcgg
    16801 actacgcgcg aagacggact ctagtgcggg aagcggcggg gtgggcgagt ga
//
