LOCUS       reptomyces_RBGC_104116 16536 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_104116
VERSION     Streptomyces_RBGC_104116
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001279885.1
  ORGANISM  GCF_001279885.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1545
                     /protein_domains="PF07690"
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685545"
                     /pseudo=False
                     /translation="VSAGTKTPTDPAGRRVLSAALFASAPAEVLDFLLPLWAGSTLNAG
                     ASVVGALIAFEAVLSLIVRPLAGELADRFDQRRVAAAGAGLYALSFAGYALADSLPVAF
                     AAAGLGGAGGALFWVALRAWTGQEARDGDGTAAYGKLLSAEGQGAFVGYLVAFSLLERT
                     GYPALFWLGAAACVLAAALLLRGPGRRPAARPGAYAAGAGGLFRRGAAERRLLPLMVVS
                     AVTAAAEAGLWMLLLLRLQGDLGLSPNEIAMVFAPGFVVFVLLPEHTHHLTDRLGRTPT
                     MVASFAAGALFAAGLAVVSTPLAIAVFWTVAAACFAAQIPVEQATVAAASGGRIGRGMG
                     LYETARLAGVVAGPLVMGVLYEELGWVAACAAAAATSAVGAVVVPFAVRVLRLPREENN
                     AATQSVHMTEDGEDMDTSKPEPAQPSAEPALGPKEHARKERRDWYIHTVAFALGQLVLW
                     ALDSSWLVWQITDGSVPDDQRGPLVWLGRIWLTIWVIDTIWSWSYTIWPREKKAKS*"
     CDS             complement(1507..1616)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685546"
                     /pseudo=False
                     /translation="VIPDGRRPGAKSPGPVTHHAVRRGYDFAFFSRGQMV*"
     CDS             complement(1614..2842)
                     /protein_domains="PF00067"
                     /protein_domains="PF00067"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685547"
                     /pseudo=False
                     /translation="MSDDRVQVRRALRALFSPLGCPDPYPLYAVLRERAPVARLPDGTV
                     VVTRHADCDRVLRDPLFRVEDDEWIARTWPEGPEHLAVHSLMGEMVNQNSPHHERLRRL
                     VSRAFTPRRVEELRPAVQRLTDALLDDLAEHASTGPVDLMERLALPLPITVIGELLGIP
                     EEDRAWFGPRVRDITSAIEHNLLGPDLERADAATAELWDRLGALVAERQADPREDMVST
                     LIAVRDADGDRLTHRELLANLVLLYSAGYETTSNLIGNGTATLLDHPGLLARLRGEPDN
                     VAAWVDEMLRFTPPIQIASRWTGEDTELHGVHIEKGTQVVALLAGANRDPERYESPDTF
                     LPGRPVSGSLSFGAGAHYCLGAALARMEAQVVFPRLLARFPHIAHAGPALARTRVTSLR
                     GYDRLPLDLR*"
     CDS             complement(2951..3195)
                     /protein_domains="PF00550"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685548"
                     /pseudo=False
                     /translation="MTREEIISGLAEILNEVADVEPADVTEEKSFIEDLDVDSLAMVEV
                     IVAAEERFGVSLPEEELKELRLVSDIVIRIEKQLAG*"
     CDS             complement(3305..4254)
                     /protein_domains="PF00268"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685549"
                     /pseudo=False
                     /translation="MPRWSTLLLDDASLAEMPELPLKDVLRHADLVTEQQPQPQALYER
                     WEKQQWSAQAIELGPDREDFDKRLPKAARKMIEESIATFIIGEYTGLDLLGPILTGAPE
                     ERDHLYLGTQIADETRHTQLMLRLGEELLGLDPDPKRMLVQAWNMVTPAHQELSRVETE
                     IIRELQQHPSDYRRWLRAVALFHLITEGVLALVGQRAIVNSLHGIPLLAGLKAGFTAMC
                     RDESRHVSFGLHALRQGVLEGYGDDIREIIELAAPIALNIEEGGEVDSAPQGLTMKQLG
                     IESLYRQLRLIGIEKEFADHVVDLSALKPAAEEDR*"
     CDS             4502..5820
                     /protein_domains="PF00109"
                     /protein_domains="PF02801"
                     /protein_domains="TIGR03150"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685550"
                     /pseudo=False
                     /translation="MTQTRAGAPERRVVITGSGVVSPIGCTTEEFWASATAGRSGIRTI
                     TRYDGDTLPTRFAGEVVDFDPKPYMPNKQGRRLDRYAQFALAAALQAVRQAGLEIDGER
                     AVRTAVLVGSGYGPGQLMQSAIHDLRDHGRRRMTPYLASSGSLDSAAGEIAFRLGARGP
                     SGATATACATGATCIGDAMRMIRHGYADVVIAGGADDAVNPLDLAAAANAGALSRRDDE
                     PGRASRPFDRARDGFVMGAGAGVVVLESAEHARRRGATVLAELAGYGATTDAYHSTHPH
                     PEGLAARQAMTDALDDAGVRPEEIDHISAHGTGTQLNDRIESASIRAVFGRHALRVPIS
                     SLKSMTGHMIGAAGAVELIAAVHTIRDGIVPPTVNCDDPEDTELDYVPHTARPHAVRTV
                     LSNSFGFGGHNAVLVLRAPSGPSRTPSQSPSMPESQGGER*"
     CDS             5818..8441
                     /protein_domains="PF00069"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685551"
                     /pseudo=False
                     /translation="MTSTRPQPEEYCQASRVFYDIAGRHNEDDTSWFAQTGAPAHEGFE
                     RREMDVWIVHTPVGHVMPQQGWKIHISGLPDNARRIVDAAWDYCTREGLPFKFLRSVDV
                     LTTHSLKYAPRSSSGKLVTIYPSDEHQLRRALEELGGLLDGEAGPYILTDLRWNAGPLH
                     VRYGGFVARWCTDEDGSPVAAIERPDGTLVPDRRRPVFEVPEWIQLPPFLAEQLAAREA
                     SGSAADFPYRVERALHFSNGGGVYLAKDAEGRQVVLKEGRPHAGLDGRGRDAVTRLARE
                     RRAMEHLAGIPGIPALYEHRVVWEHHFLAVQHLEGDTLQGWLARHYPLTKAGPTDGELT
                     AYADRAQAVADRIDRLVAEVHARGMVFGDLHPANILIDDEDRVSLVDFELAVPVEEADR
                     LGLGHPGFAGAGRTGFDIDRHALAALRLWLLFPLTGLNELDPGRGVRQADIAERRFALP
                     AGSLDAVRRELAPGEQARDRVPPVLRETLSVDLDEDRPDWAAVRKSLAEAVLLSATPER
                     DDRLFPGDVRQFLTDGTGLAHGAAGVLWALHTSGAGRFPEHEEWLLKAAARRAPSRPGL
                     YDGAHGVAHVLREFGHLDAAEGLLARSAEAVDALRDLSLQRGTAGIGLDLLDAAARTGG
                     GDHLSRALGLADRMADAIALGTAPGITAGPGRGSRAGLLRGWSGPALFFLRLYEDTADT
                     AHLDLAVRALHHDLDLCGVAEDGSLQVDGGFRLLPYLEVGSAGIALVADQVLAHHRDAR
                     LEQALPLLVRAAEPEFTIEPHLFGGRAGLLATLASLRGRAAGTAPGTAVARHLSRLHWH
                     ALSYRGHLAFPGEQLRRVSMDLATGSPGILLALTAALDGRRDFLPFLAPRTDRPTGVDH
                     HAP*"
     CDS             8439..8593
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MSSGRHQPTGCPLTPIHRRGGNIMSIVLDLQGLEVPAEETTRVAS
                     TASNHC"
     CDS             8725..9494
                     /protein_domains="PF13561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685552"
                     /pseudo=False
                     /translation="MSGLLDGKRLVITGVITESSIAYAVARLAQQEGARIVLTAYGRTS
                     LVRRLARRLPHEAPVVELDVTAPDQLATLADRVGEHLDGVDGVLHSIAYAPAECLDGGF
                     MSAGWPEVSTALHTSTYSLQALTVACRPLLRPGASVVGVDFDASRAWPGYDWMGVAKAG
                     LEACSRYLARELGPDGIRVNLVAAGPLRTLAARGIGGDGPAFETGWATRAPLGWDSADA
                     DPVARTCLALLSDWLPATTGEIVHADGGHHMIGS*"
     CDS             9497..10524
                     /protein_domains="PF00491"
                     /protein_domains="TIGR01230"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685553"
                     /pseudo=False
                     /translation="VHHLGSAHGPDITFLGVPRLDLSDPPEDADVVILGAPFDGGTSHR
                     PGARFGPSAMRQACYLPQNGARRSLAMGVDPLTELKVYDAGDVPCYSGDIEQSIRSIEQ
                     AVRMTAALGAIPVVLGGDHTIALPDMRGLARHHGFGRIAMLHFDAHADTGEVEDGPLYG
                     HGKPMRQLIESGAVRGDRFLQIGLRGYWPGPDTLRWMAGEGMRSYEMSEITSRGLPACL
                     TEAFAVAMDDCDGVFLSVDVDVVDPGQAPGTGTPEPGGLTSRELLDAVRRIAYELPVVG
                     VEVVEVAPPYDHADITAYLGNRVVLEALSGIARRRRDLALGTRWDPRTPLLERETREGA
                     HR*"
     CDS             10522..12002
                     /protein_domains="PF00501"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685554"
                     /pseudo=False
                     /translation="VTATRTEEPTVRTAPPGRAAGAPAAAPGLADAAGTLTGAALTGRV
                     LAAAGELRGRGVGPGDRVLVKGDNSVDYVVALLALMHLDASLVPVDHRQSAADGRFAAR
                     RARARWLLTREAVAADFPAESVLAYPGLGAGHPPLDADVDLTAWFARADAVVLWSSGTT
                     GPPKAIVKSGRAVHDNTRRTIAAMGYRADDVLAPLLPFSHQYGLSVVLLWWLARCTLAV
                     TPYQRLDVALAQAAGHGVTAVDAAPSTYHSLLGVVRRRPELRAALSRVRVWGVGGAPLP
                     APLAEAFPAALGRPLLDGYGLTELGNVALATPDVPTGCGRPLPGIRVRVLRPDGEPAAP
                     GELGEIEVLSPGLMEGHLLDDGTLAPVPRDSWYPTADLGHLDADGHLYVVGRNQAVHRS
                     GFTLYPESLERKAEACGRQVKALAVEDLRRGCALHFVVADPDGGSPAQWRLRMAPHLAE
                     YEQPNAVHVVDRFPLSANGKTDTAALRKMVGVAAA*"
     CDS             complement(12079..13217)
                     /protein_domains="PF02801"
                     /protein_domains="PF00109"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685555"
                     /pseudo=False
                     /translation="VSDIVISGLGLVTPFGRGVEPYWRGLLGGRSALGPARRFTEPPYR
                     GEPVGEVPRAAGPEPDGGPRKSAYARAALGEALHAAGLDRLPDGAVVLLVGQAVLPRPG
                     DGRALPTADEREFMGPDPAEVLGVRPDLRHVHLSHACASAVFAVGYARELLRAGAAPLA
                     AVVGSSVLNRYEYASMDVVRAVGRTAARPFDVERAGISLGEGGGAVVLESAGHARARGA
                     SADLAVAGAACRVAGAKAAASDTDRIAACMRDALDDASVHGLDHVHAHATGTGQGDAAE
                     LAAVEAVAADCGARALPVSSHKGAIGHLLHISGAPAIAAAAGMLRGGIVPPTAGLTTPE
                     PTDRLVLPTAPMEVAGARTAAVNSFGFGGNNASLVLLRR*"
     CDS             complement(13215..13735)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685556"
                     /pseudo=False
                     /translation="MTTGTRRPVAVPWHRALAGTDEARVAAVPVPTAAPSVHRKPAEAA
                     SAALGAAFGALSEDVRATAALYVLCHDYGTWAARRFVARCHDPARRLRPSDSVGMETSE
                     LVRPYLTASEHRGDCYLLARPPASGEEFTPPVTAARPAAVVLDLIVFPGEDPRDADCLA
                     LATTWKASGL*"
     CDS             13820..15000
                     /protein_domains="PF00201"
                     /protein_domains="TIGR01426"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685557"
                     /pseudo=False
                     /translation="MPLRVGFVGIAWHGHVNPTLGLVEELVRRGHRVSYAVTEAFAETV
                     RAVGAEPVVYRNPVDDALTDDGLDISPTDFLREAEATLPVLKQAWATDRPDVIAYDGIA
                     WAGRVLAAAWQLPAAEMWPSFVSNEHFSLEAEFLADQPLHPGVLRFVRELTRFLTAHGL
                     PATSAGDFLGHTEPLRLVFLPRSFQYRGETFDDRFAFVGPCAGDRGFQGDWSPAADRRP
                     VLLIALGTACYEWPEFFRMCGEAVADLPWQVVMAHGPGIDPDDLGPLPDHVDARPYVPQ
                     LAVLRHADAFVTHAGMGSTMEALLHGTPMVAVPQTHEQAAVAERIGRLGLGVRLDREQL
                     TAHTLREALVRVMDDTRIRANAARMRDDLRSAGGAPEAADRLELLVASAADAA*"
     CDS             15048..15778
                     /protein_domains="PF13302"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685558"
                     /pseudo=False
                     /translation="MQGKLVRLERPRDEDYELMARWFGPDAPAAVMAATDGDVVTAEEF
                     RRLDQSGGLRQFAVRDAEDRTVGAVHFKAQGPVGGYVLGGAIGDRELWRRGLGAEAFDL
                     LIDHLFHARNAHRVQFTTALYNKNVLRLVTGVGFTLEGILREYFYLDGRHHDGAVWGLL
                     RHEYYAAVEELKRTDATFSLPDAIPEADKEQARRLLAEYIASPFGKTSTGLLLAAAGVA
                     PVDRDRDRTLEGDRLPGADER*"
     CDS             15776..16536
                     /protein_domains="PF02585"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4685559"
                     /pseudo=False
                     /translation="VTSQRWSTLVLSPHFDDAALSVAGLLGRLDGPAAVVTVHGGAPPE
                     RAPVSWWDAGCGFATAREAHRARLAEDARACALMGVEQLTLPNADSPYRDGGPLTGLSE
                     LLRELHPDTRVLVPLGTNQPDHAAVRDQALAALTDPAGPRPYVYADLPYTGAVRRWGTD
                     AAVERLTRDPAYGGALRETAARYRMRVAYDVRLDDTEWAAKRAAIVCHSSQLAPVAVGH
                     GPFLRRPGPLQAELVWELEPLGDPTAHTREP*"
ORIGIN
        1 gtgagcgccg ggaccaagac gccgacggac ccggcagggc gccgggtcct gtcggcggca
       61 ctgttcgcga gcgccccggc cgaggtgctc gacttcctgc tgccgctgtg ggccggttcg
      121 acgctgaacg ccggcgcgtc cgtggtgggc gccctcatcg ccttcgaggc ggtgctgtcg
      181 ctgatcgtgc gccccctggc cggggaactg gccgaccgct tcgaccagcg gcgggtggcc
      241 gcggccggcg cgggcctgta cgccctgtcg ttcgcggggt acgcgctcgc cgactccctg
      301 ccggtggcct tcgccgcggc gggcctgggc ggcgcgggcg gcgcgctgtt ctgggtcgct
      361 ctgcgggcct ggaccgggca ggaggcacgg gacggcgacg gcacggcggc ctacgggaag
      421 ttgctctccg ccgagggcca aggcgccttc gtgggctacc tggtggcgtt ctccctgctg
      481 gaacggaccg gctatcccgc gctgttctgg ctgggcgccg ccgcctgcgt gctggccgcg
      541 gccctgctgc tgcgcgggcc gggcaggcgg ccggccgccc gcccgggcgc gtacgctgcg
      601 ggggcgggtg ggctgttccg gcgcggtgcg gccgagcgcc ggctgctgcc gctgatggtg
      661 gtgtccgcgg tgacggccgc cgccgaggca gggctgtgga tgctgttgct cctgcggctg
      721 cagggggacc tgggcctgtc gcccaacgag atcgccatgg tcttcgcccc cggcttcgtg
      781 gtgttcgtgc tgctgccgga gcacacccac cacctcaccg accggctggg ccggaccccg
      841 acgatggtcg cctcgttcgc ggcgggcgcg ctgttcgcgg cggggctggc ggtcgtctcc
      901 acgcccctcg cgatcgccgt gttctggacc gtggccgcgg cctgtttcgc ggcgcagatc
      961 cccgtcgagc aggcgaccgt ggccgccgcg tccggcggcc ggatcggccg gggcatgggc
     1021 ctctacgaga ccgcgcgcct ggccggtgtg gtggccgggc cgctggtgat gggggtgctc
     1081 tacgaggaac tcggctgggt cgccgcctgc gcggcggccg ccgccacctc cgccgtgggg
     1141 gcggtcgtgg tgccgttcgc ggtccgcgtc ctgcgcctgc cgcgggagga gaacaacgcc
     1201 gcgacgcaat cagtacacat gacagaggac ggagaagaca tggacacgag caagccggaa
     1261 ccggcgcagc cttcggcgga gcccgccctg gggccgaagg agcacgcccg caaggagcgc
     1321 cgtgactggt acatccacac ggtcgcgttc gcgctggggc agctggtcct gtgggccctg
     1381 gactccagtt ggctcgtatg gcagatcacg gacggcagcg tgcccgacga ccagcgcggg
     1441 ccgctggttt ggctgggccg gatctggctg accatctggg tgatcgacac catctggtcg
     1501 tggtcctaca ccatctggcc gcgggagaag aaggcgaagt cgtagccccg ccgtacggcg
     1561 tggtgcgtga ccggcccggg gctcttcgcc ccgggccggc ggccgtccgg gatcacctca
     1621 ggtccagcgg gagccggtcg tagccgcgca gcgaggtgac gcgcgtacgg gccagcgccg
     1681 gcccggcgtg ggcgatgtgc gggaagcggg cgagcagccg ggggaagacg acctgggcct
     1741 ccatcctggc gagggcggcg cccaggcagt agtgcgcgcc ggcgccgaag ctgagcgagc
     1801 cggacacggg cctgcccggc aggaacgtgt cgggggactc gtaccgttcg gggtcgcggt
     1861 tcgccccggc gagcagggcc acgacctggg tccccttctc gatgtgcacc ccgtgcagtt
     1921 cggtgtcctc gccggtccag cgcgaggcga tctggatggg cggggtgaag cgcagcatct
     1981 cgtctaccca ggcggcgacg ttgtcgggct caccgcgcag gcgggcgagg agcccggggt
     2041 ggtcgaggag ggtggccgtg ccgttgccga tgaggttgct cgtcgtctcg tagcccgcgg
     2101 agtacagcag gaccaggttg gcgagcagtt cgcggtgggt gagccggtcg ccgtccgcgt
     2161 cgcggaccgc gatgagcgtg ctcaccatgt cctcgcgcgg atcggcctgc cgctcggcca
     2221 ccagcgcgcc caggcggtcc cacagttcgg cggtcgccgc gtcggcgcgc tccaggtcgg
     2281 ggccgaggag gttgtgctcg atggcggagg tgatgtccct tacccgcggg ccgaaccagg
     2341 cccggtcctc ctcgggaatg ccgagcagtt cgccgatgac ggtgatgggg agcggcaggg
     2401 cgagccgttc catcaggtcg accgggccgg tggaggcgtg ttcggcgagg tcgtccagca
     2461 gggcgtcggt cagccgctgc accgccggcc gcagttcttc cacgcggcgc ggggtgaagg
     2521 cccggctgac caggcgccgc agccgctcgt gatggggcga gttctgattg accatctcgc
     2581 ccatgaggga gtggacggcc aggtgctcgg ggccctcggg ccacgtgcgg gcgatccatt
     2641 cgtcgtcctc gacccggaag aggggatcgc gcagcacccg gtcgcagtcg gcgtggcggg
     2701 tgacgaccac ggtcccgtcg ggcagccggg ccacgggggc ccgttcgcgg agcaccgcgt
     2761 agagggggta ggggtcgggg cagccgagcg ggctgaacag ggcgcgaaga gcgcggcgta
     2821 cctggacccg gtcgtcgctc atggtgcctc ctggccccgg gctcgtgcgg gcgagtccgg
     2881 gtgtgggtgg atgcgccgct ccggtcccgg agcgggccgg gccgaagcag cagcgcaagg
     2941 atcgggcggt cagccggcca gctgcttctc gatccggatc acgatgtcgg agaccagtcg
     3001 gagctccttc agctcctcct cgggcaggct caccccgaag cgctcctcgg cggcgacgat
     3061 gacctcgacc atcgccaggg agtcgacgtc gaggtcctcg atgaaggact tctcctcggt
     3121 cacgtcggcc ggctccacgt cggcgacctc gttcaggatc tcggcgaggc cggagatgat
     3181 ttcttcacgc gtcatggcgg ttacctctct tggggtgtgt ggctgtggct gtggctgtgg
     3241 ctgtgggtgt ggctgtgggg cgggggagcg cggtgcggcg ccggccgggc gtgcggcggc
     3301 ggctcagcgg tcctcttcgg cggccggctt cagcgcggag aggtcgacga cgtggtcggc
     3361 gaactccttc tcgatgccga tgagccgcag ttggcggtac aggctctcga tgccgagctg
     3421 cttcatggtg agcccctgcg gggccgaatc cacctcgccg ccctcctcga tgttgagggc
     3481 gatcggcgcg gcgagctcga tgatctcgcg gatgtcgtcg ccgtagccct ccagcacgcc
     3541 ttggcgcagc gcgtgcaggc cgaagctgac gtgccgggac tcgtcgcggc acatcgccgt
     3601 gaagccggcc ttcagtccgg cgagcagcgg gatgccgtgc agggagttca cgatggcccg
     3661 ctgcccgacg agggccagga cgccctcggt gatcaggtgg aagagggcga ccgcgcgcag
     3721 ccagcggcgg tagtccgagg ggtgctgctg cagctcccgg atgatctcgg tctcgacgcg
     3781 gctgagttcc tggtgggcgg gcgtgaccat gttccacgcc tgcaccagca tccgcttggg
     3841 gtcggggtcc aggccgagga gctcctcgcc gaggcgcagc atcagctgcg tgtggcgggt
     3901 ctcgtcggcg atctgcgtac cgaggtagag gtggtcgcgc tcctcggggg ccccggtgag
     3961 gatcgggccc aggaggtcga gaccggtgta ctcgccgatg atgaaggtgg cgatggactc
     4021 ctcgatcatc ttgcgtgcgg ccttcgggag ccgcttgtcg aagtcctcgc ggtcggggcc
     4081 gagttcgatg gcctgggccg accactgctg cttctcccag cgctcgtaga gagcctgtgg
     4141 ctgtggctgc tgttcggtga cgaggtcggc gtgccgaagg acgtccttga ggggcagctc
     4201 cggcatctcg gcgagcgagg cgtcgtcgag cagcagtgtg ctccagcgcg gcatatcaac
     4261 tctccatgac tcttgagtca agttcatgac tatccatgaa ttccacagtg aacagcacga
     4321 gcggcgcatc gtcaacgtgg atgagtgagt gccggggtgg gctccgagaa tcgctcagtc
     4381 atgtttcttg actcttgagt cgagagtgtg tcaatgtttg gtcatcgccc cgacgggacg
     4441 gccaacaggc cccttccgca gggtggttga cgcccacggc aatcaaggag ggagacggac
     4501 atgacgcaga cacgggctgg tgccccggaa cgccgcgtgg tcatcaccgg cagcggtgtc
     4561 gtctccccca tcggttgcac caccgaggag ttctgggcct cggccaccgc cgggcgcagc
     4621 gggatccgca ccatcacccg ctacgacggc gacacccttc cgacccggtt cgccggcgag
     4681 gtcgtggact tcgatccgaa gccgtacatg cccaacaagc agggccgccg actcgaccgg
     4741 tacgcccagt tcgccctcgc cgccgccctc caggcggtac ggcaggccgg actggagatc
     4801 gacggggaac gcgccgtgcg gaccgccgtc ctggtgggct ccggctacgg accgggccag
     4861 ctcatgcagt cggccatcca cgacctgcgc gaccacggac ggcgccggat gaccccgtac
     4921 ctcgcctcca gcggttcgct ggacagcgcg gcgggcgaga tcgccttccg gctcggcgca
     4981 cggggcccct ccggcgccac cgccaccgcc tgcgcgaccg gtgccacctg catcggtgac
     5041 gcgatgcgca tgatccgcca cggttacgcg gacgtcgtca tcgccggcgg ggccgacgac
     5101 gcggtcaatc cgctcgacct cgccgccgcc gccaacgccg gtgcgctctc ccgccgcgac
     5161 gacgaaccgg gccgtgccag ccgtcccttc gaccgggccc gggacgggtt cgtcatgggc
     5221 gccggcgcgg gagtcgtcgt cctggaatcc gccgagcacg cccgccgccg cggcgccacc
     5281 gtactggccg aactggcggg ctacggcgcg accaccgacg cctaccactc gacccatccc
     5341 caccccgagg gcctcgccgc ccggcaggcc atgaccgacg ccctggacga cgcgggggtg
     5401 cggcccgagg agatcgacca catctccgcc cacggcaccg gcacccagct caacgaccgc
     5461 atcgagagcg cgtcgatccg cgccgtgttc gggcgccacg ccctgcgtgt ccccatcagc
     5521 tcgctcaagt cgatgaccgg tcacatgatc ggcgccgccg gcgcggtcga gctgatcgcc
     5581 gcggtccaca cgatccgcga cgggatcgtg ccgccgaccg tgaactgcga cgaccccgag
     5641 gacacggagc tggactacgt gccgcacacc gcgcgtcccc acgccgtgcg caccgtgctc
     5701 agcaattcgt tcggattcgg cgggcacaac gccgtgctcg tgctccgggc cccgtccggg
     5761 ccgtcccgga cgccgtcgca gtccccgtcg atgccggagt cccagggagg agagcgatga
     5821 ccagcacgag gccgcagccc gaggagtact gccaggccag ccgcgtcttc tacgacatcg
     5881 ccggccgcca caacgaggac gacacctcct ggttcgccca gaccggcgcc ccggcccacg
     5941 agggcttcga gcgccgcgag atggacgtgt ggatcgtgca cacgccggtc ggccacgtca
     6001 tgccgcagca gggctggaag atccacatct ccggtctgcc ggacaacgcc cggcgcatcg
     6061 tggacgccgc ctgggactac tgcacccgcg agggactgcc gttcaagttc ctgcgcagcg
     6121 tcgacgtgct gaccacccac agcctcaagt acgccccgcg ctcctccagc ggcaagctgg
     6181 tgacgatcta cccgagtgac gaacaccagc tgcgccgcgc cctggaggaa ctgggcggcc
     6241 tcctcgacgg cgaggcgggc ccctacatcc tcaccgacct gcgctggaac gccgggccgc
     6301 tgcacgtgcg ctacgggggc ttcgtcgccc ggtggtgcac cgacgaggac ggttctcccg
     6361 tcgcggcgat cgaacgcccc gacggcaccc tggtccccga ccggcgccgg cccgtgttcg
     6421 aggtgcccga gtggatccag ctgcccccct tcctggccga gcagctcgcg gcccgcgagg
     6481 cgagcggctc cgccgcggac ttcccctacc gggtcgagcg cgccctgcac ttctccaacg
     6541 gcggcggcgt ctacctggcg aaggacgccg aagggcgcca ggtcgtcctc aaggagggcc
     6601 gcccccacgc gggcctcgac ggccgcggca gggacgccgt gacccgcctg gcgcgggagc
     6661 gccgggccat ggagcacctc gccggcattc ccggcatccc ggccctgtac gagcaccgcg
     6721 tcgtgtggga gcaccacttc ctggccgtgc agcacctgga gggcgacacc ctgcagggct
     6781 ggctggcccg gcactacccg ctgaccaagg ccggaccgac cgacggtgaa ctgaccgcct
     6841 acgccgaccg ggcgcaggcc gtggccgacc gcatcgaccg gctcgtggcc gaggtgcacg
     6901 cccgcggcat ggtcttcggc gacctgcacc cggcgaacat cctcatcgac gacgaggacc
     6961 gcgtctcgct ggtcgacttc gaactcgccg tccccgtcga ggaggcggac cggctcggcc
     7021 tcggccaccc cggtttcgcc ggagccggac gcaccggctt cgacatcgac cggcacgccc
     7081 tggccgccct gcgcctgtgg ctgctgttcc cgctcaccgg gctgaacgag ctcgacccgg
     7141 ggcgcggggt gcgccaggcg gacatcgccg agaggcggtt cgccctgccc gccggcagtc
     7201 tggacgccgt acgccgtgaa ctggcccccg gcgagcaggc ccgcgaccgg gtgccgcccg
     7261 tgctccgcga gacgctgagc gtggacctcg acgaggaccg gcccgactgg gcggccgtac
     7321 gcaagtccct ggcggaagcc gtcctgctct cggccacccc cgagcgcgac gaccggctct
     7381 tccccggcga cgtacggcag ttcctcaccg acgggacggg cctcgcccac ggtgcggcgg
     7441 gcgtcctgtg ggcgctgcac acctcgggcg cggggcgctt ccccgagcac gaggagtggc
     7501 tgctcaaggc cgccgcccgg cgggcgccgt cgcggccggg cctctacgac ggggcgcacg
     7561 gagtcgccca cgtcctgcgg gagttcggcc acctggacgc ggccgaagga ctgctggccc
     7621 gcagcgcgga ggccgtcgat gcgctgcgcg acctgagcct gcagcgcggc accgcgggca
     7681 tcggcctcga cctgctggat gccgccgccc gcacgggcgg aggcgaccac ctcagccgcg
     7741 ccctgggcct ggccgaccgg atggccgacg cgatcgccct gggcaccgcc ccgggcatca
     7801 cggccggccc cggccggggc agccgggccg ggctgctgcg cggctggtcc gggcccgccc
     7861 tgttcttcct gaggctgtac gaggacacgg cggacacggc ccacctcgac ctggcggtcc
     7921 gggcgctcca ccacgacctc gacctgtgcg gcgtcgccga ggacggctcg ctccaggtgg
     7981 acggcggatt ccggctgctg ccgtacctgg aggtgggcag cgcggggatc gcgctggtcg
     8041 ccgaccaggt cctcgcccac caccgggacg cccggctgga gcaggcgctg cccctcctgg
     8101 tgcgcgccgc cgagccggag ttcaccatcg agccccacct gttcggcggc cgggccggcc
     8161 tgctggcgac gctcgcctcg ctgcgcggcc gcgccgcggg aacggcaccc gggacggccg
     8221 tggcgcggca cctgtcgcga ctgcactggc acgcgctgtc ctaccgcggc cacctcgcct
     8281 tccccggcga gcagttgcgc agggtctcga tggacctggc caccggcagc cccggcatcc
     8341 tgctggccct caccgcggca ctcgacggac ggcgggactt cctgcccttc ctggcgccgc
     8401 gcacggaccg ccccaccggc gtggaccacc acgccccctg agctccggac ggcatcagcc
     8461 gaccggttgt ccactgaccc cgatacatcg gagaggagga aacatcatgt cgatcgttct
     8521 cgacctgcag ggccttgagg tccccgccga ggagaccacg cgcgtcgcca gcaccgccag
     8581 caaccactgc tgaacgagct gagcagctcc ggtgcccgcc ctttccgggc gggccccgga
     8641 gctcgtccat ttccgcgcgc gctccgcgcg ttctgcgcgc cggaccgacc ccggcgcccc
     8701 gaaggacctt gagggagacc cgtatgagcg gcctgctcga cggcaagaga ctcgtcatca
     8761 ccggcgtgat caccgagagt tcgatcgcct acgcggtggc acgcctcgcc cagcaggagg
     8821 gcgcgcgcat cgtcctcacc gcgtacggac gcacctcgct ggtgcggcga ctcgcccgcc
     8881 ggctgcccca cgaagcaccg gtcgtggaac tcgacgtcac cgcgcccgac cagctggcca
     8941 cgctcgcgga ccgcgtcggc gagcacctcg acggcgtcga cggcgtgctc cactcgatcg
     9001 cgtacgcccc ggccgaatgc ctcgacggcg gcttcatgag cgccggatgg cccgaggtct
     9061 ccaccgccct gcacacctcc acgtactcgc tccaggccct cacggtggcc tgccggcccc
     9121 tgctccgccc cggcgcgtcc gtcgtgggcg tggacttcga cgcctcccgg gcctggcccg
     9181 gatacgactg gatgggcgtg gccaaggcgg gactggaggc gtgcagccgc tacctcgcgc
     9241 gcgagctcgg tcccgacggc atccgggtca acctggtcgc ggccggcccc ctgcgcaccc
     9301 tggccgcccg tggcatcggc ggcgacggac cggccttcga gaccgggtgg gcgacacgcg
     9361 cccccctcgg ctgggactcc gcggacgcgg accccgtcgc ccgtacctgc ctggcactgc
     9421 tgtcggactg gctgcccgcc accacggggg agatcgtcca cgcggacggc ggccaccaca
     9481 tgatcgggag ctgacgtgca ccacctggga tcggcccacg ggcccgacat caccttcctc
     9541 ggcgttccgc ggctcgacct gtccgacccg cccgaggacg ccgacgtggt catcctcggc
     9601 gcccccttcg acggcggcac ctcgcaccgg cccggcgccc gcttcggccc gtcggcgatg
     9661 cgccaggcct gctacctgcc gcagaacggc gcacgccgca gcctggccat gggcgtggac
     9721 ccgctgacgg aactgaaggt gtacgacgcc ggcgacgtcc cctgctactc cggcgacatc
     9781 gagcagagca tcaggagcat cgagcaggcg gtacggatga cggccgcgct cggggcgatc
     9841 cccgtcgtgc tcggcggcga ccacacgatc gcgctccccg acatgcgcgg gctggcccgc
     9901 caccacggct tcggacgcat cgcgatgctg cacttcgacg cccacgccga caccggcgag
     9961 gtcgaggacg gcccgctgta cggccacggc aagccgatgc gccagctcat cgagtcgggc
    10021 gcggtgcgcg gcgaccgctt cctccagatc gggctgcgcg gctactggcc cggcccggac
    10081 accctgcgct ggatggcggg cgagggcatg cgctcgtacg agatgtccga gatcacctcg
    10141 cgcggcctgc cggcctgcct caccgaggcc ttcgccgtcg ccatggacga ctgcgacggg
    10201 gtgttcctgt cggtcgacgt ggacgtggtg gaccccggcc aggcgccggg caccggcact
    10261 ccggagccgg gcggcctgac atcccgcgaa ctgctggacg cggtgcgccg gatcgcctac
    10321 gagcttcccg tggtcggcgt cgaggtcgtc gaggtggcgc ccccctacga ccacgccgac
    10381 atcaccgcct acctgggcaa ccgggtcgtc ctggaggcgc tgtccggcat cgcccggcgg
    10441 cgccgcgacc tggccctggg cacgcggtgg gacccgcgca cccccctgct ggaacgggaa
    10501 acgcgagaag gagcacaccg gtgaccgcga cgaggaccga ggaaccgacg gtacggacgg
    10561 cgcccccggg ccgggcggcc ggcgcacccg ccgccgcccc cggcctcgcc gacgcggccg
    10621 gcacgctcac cggggccgcg ctcaccggcc gggtgctcgc cgccgcgggg gagctgcgcg
    10681 ggcgcggcgt cggaccgggc gaccgggtcc tggtcaaggg ggacaactcc gtcgactacg
    10741 tcgtggcgtt gctcgccctg atgcacctgg acgcctcgct ggtgccggtg gaccaccgcc
    10801 agtcggcggc ggacggacgg ttcgcggccc gccgggcgcg ggcgcgatgg ctgctgaccc
    10861 gtgaagcggt cgccgccgac ttccccgccg agagcgtgct ggcgtatccc ggtctcggtg
    10921 cgggccaccc cccgctcgac gcggacgtcg acctcaccgc gtggttcgcc cgcgccgacg
    10981 ccgtggtgct gtggtcctcg ggaacgaccg gcccgcccaa ggcgatcgtg aaatccgggc
    11041 gagccgtcca cgacaacacc cggcgcacca tcgcggccat gggctaccgg gcggacgacg
    11101 tgctcgcccc gctgctgccc ttctcccacc agtacgggct gtccgtggtg ctgctgtggt
    11161 ggctggcccg ctgcacgctg gccgtcacgc cctaccagcg gctcgacgtg gccctcgccc
    11221 aggccgccgg gcacggggtc acggccgtgg acgcggcccc gtccacctac cactccctgc
    11281 tcggggtcgt gcgccgccgc cccgagctgc gcgccgcgct gagccgcgta cgcgtctggg
    11341 gcgtcggcgg cgccccgctg cccgcgccgc tggcggaggc cttccccgcc gccctgggcc
    11401 ggcccctcct cgacgggtac ggactcaccg aactcgggaa cgtcgcgctg gccacccccg
    11461 acgtgcccac cggctgcggc aggccgctgc cgggcatccg ggtacgggtg ctgcgcccgg
    11521 acggcgaacc ggccgccccc ggcgagctcg gcgagatcga ggtgctctcg cccgggctga
    11581 tggagggcca cctgctcgac gacggcacgc tcgcccccgt accgcgggac tcctggtacc
    11641 cgacggccga cctcgggcac ctcgacgccg acggccatct gtacgtggtg gggcgcaacc
    11701 aggcggtgca ccggtcgggc ttcacgctgt atccggagag cctggagcgc aaggccgagg
    11761 cctgcgggcg acaggtcaag gcgctggcgg tggaggacct gcggcgcggc tgcgccctgc
    11821 acttcgtcgt ggccgacccc gacggcggct cgccggccca gtggcgcctg cggatggccc
    11881 cgcacctggc ggagtacgaa cagcccaacg ccgtccacgt cgtcgaccgc tttccgctga
    11941 gcgccaacgg caagaccgac acggcggccc tgcggaagat ggtcggtgtg gcggccgcct
    12001 gatccggccc ggccgacagg acaccccctg gtgccggtcg ctccgcccga cccccgcggg
    12061 cggagcgacc tgtgggttca ccgccggagc aggaccagcg aggcgttgtt gcccccgaag
    12121 ccgaagctgt tcacggcggc cgtccgggcg ccggcgacct ccatcggggc cgtgggcagc
    12181 accagccggt cggtgggctc cggggtggtg aggcccgccg tgggcgggac gatcccgccg
    12241 cgcagcatcc cggcggccgc ggcgatcgcc ggtgcgccgg agatgtgcag caggtggccg
    12301 atggcgccct tgtgcgaact gacgggcagg gcgcgggcgc cgcagtccgc ggcgacggcc
    12361 tcgacggcgg ccagttccgc cgcgtcgccc tgaccggtcc cggtcgcgtg cgcgtgcacg
    12421 tggtccagcc cgtgcaccga ggcgtcgtcg agggcgtcgc gcatgcaggc ggcgatccgg
    12481 tcggtgtccg aggcggcggc cttggcgccg gcgacccggc aggccgcgcc cgcgacggcg
    12541 aggtccgcgg acgccccgcg ggcgcgggcg tgtccggcgc tctccaggac gacggcgcca
    12601 ccgccctcac cgagcgagat gcccgcccgt tcgacgtcga agggccgggc ggccgtgcgg
    12661 ccgacggccc ggacgacgtc catgctggcg tactcgtacc ggttgagcac cgacgagccc
    12721 accaccgcgg cgaggggcgc ggcgcccgcg cgcagcagct cgcgggcgta cccgacggcg
    12781 aagactgcgg aggcgcaggc gtgcgagagg tgcacgtggc gcaggtccgg gcgcaccccg
    12841 aggacctcgg cggggtcggg gcccatgaac tcccgctcgt cggcggtcgg cagggcccgg
    12901 ccgtccccgg gccgggggag gacggcctgg ccgacgagga gcacgacggc gccgtccggg
    12961 agccggtcga ggcccgccgc gtgcagtgcc tccccgaggg cggcccgtgc gtaggcgctc
    13021 ttgcggggac cgccgtccgg ctccggtccg gccgcccgcg gtacctcgcc gaccggttcg
    13081 ccccggtagg gcggctccgt gaagcgccgg gcgggcccca gggcggagcg tccgccgagg
    13141 aggccccgcc agtacggctc cacgccgcgg ccgaaggggg tgaccaggcc gagtccgctg
    13201 atgacgatgt cgctcacagg ccggacgcct tccaggtggt ggcgagggcg aggcagtccg
    13261 cgtcacgcgg gtcctcgccg gggaacacga tcaggtccag tacgacggcg gccgggcggg
    13321 cggcggtgac gggaggggtg aactcctcgc cggacgcggg cggccgcgcc agcaggtagc
    13381 agtcgccgcg atgctccgag gcggtcaggt aggggcgcac cagctcggag gtctccattc
    13441 cgacggagtc cgagggccgc agtcggcgtg cggggtcgtg gcagcgggcg acgaagcgcc
    13501 gggccgccca ggtgccgtag tcgtgacaca ggacgtacag cgcggccgtc gcccgtacgt
    13561 cctcggacag cgcgccgaag gcggcgccga gggccgccga ggccgcctcc gccggcttgc
    13621 ggtgcacgga gggcgccgcc gtcggcaccg ggacggcggc cacccgggcc tcgtcggtcc
    13681 cggcgagagc ccggtgccac ggcaccgcga cgggccttct ggttcctgtc gtcatcccaa
    13741 cccctctacc gcaagtcatg atctgtcgaa tatgctcagc cggtagtcaa gttttgtcaa
    13801 cgaaaggaaa ggggagtcat gccgctccgc gtcggattcg tggggatcgc gtggcacggt
    13861 catgtgaacc ccaccctcgg cctggtcgaa gagctggtgc gccggggcca ccgggtctcg
    13921 tacgcggtca ccgaggcgtt cgccgagacc gtacgggccg tcggcgcgga gcccgtcgtc
    13981 taccgcaacc cggtcgacga cgccctcacc gacgacggcc tggacatctc gccgacggac
    14041 ttcctccggg aggccgaagc caccctgccc gtgctgaagc aggcctgggc caccgaccgg
    14101 cccgacgtca tcgcctacga cgggatcgcc tgggccggac gggtcctcgc cgccgcatgg
    14161 cagctcccgg ccgccgagat gtggccctcc ttcgtctcca acgagcactt ctccctggag
    14221 gcggagttcc tcgcggacca gccgctgcac cccggagtcc tgcggttcgt ccgcgaactg
    14281 acccgcttcc tcaccgcgca cggcctgccc gcgacatccg ccggcgactt cctcggccac
    14341 accgagccgc tgcgcctggt cttcctgccc cgctccttcc agtaccgcgg ggaaaccttc
    14401 gacgaccgct tcgccttcgt cggaccctgc gccggcgacc gcgggttcca gggcgactgg
    14461 tcccccgccg ccgaccgccg gccggtgctg ctgatcgctc tgggcaccgc ctgctacgaa
    14521 tggcccgagt tcttccggat gtgcggcgag gccgtcgcgg acctgccctg gcaggtcgtc
    14581 atggcccacg gccccggcat cgaccccgac gacctcggcc cgctgcccga ccacgtcgac
    14641 gcccggccct acgtccccca gctcgccgtc ctgcgccacg ccgacgcctt cgtcacccac
    14701 gcgggcatgg gcagcaccat ggaggccctc ctccacggga ccccgatggt ggccgtcccg
    14761 cagacccacg aacaggccgc cgtcgccgag cgcatcggcc gactggggct cggagtccgc
    14821 ctcgaccgcg agcagctgac cgcgcacacc ctgcgcgaag ccctcgtgcg cgtcatggac
    14881 gacacccgca tccgcgccaa cgccgcacgg atgcgcgacg acctgcgctc cgcgggcggc
    14941 gcccccgagg ccgccgaccg cctggaactg ctcgtcgcgt ccgccgcgga cgccgcctga
    15001 ccaccacccc ctccactcat ccagcacctt cactcaggga gtcgccatgc agggcaaact
    15061 cgtcaggctc gaacggccca gggacgagga ctacgagctg atggcacggt ggttcgggcc
    15121 ggacgccccc gccgccgtca tggccgccac cgacggagac gtcgtcaccg ccgaggagtt
    15181 ccgccggctc gaccagagcg gcggcctgcg ccagttcgcc gtccgcgacg ccgaggaccg
    15241 caccgtgggc gccgtccact tcaaggccca gggcccggtc ggcggatacg tactcggcgg
    15301 cgccatcgga gaccgcgagc tgtggcgccg cggcctgggc gccgaggcct tcgacctcct
    15361 gatcgaccac ctcttccacg cccgcaacgc ccaccgcgtg cagttcacca cggcgctcta
    15421 caacaagaac gtgctccgcc tggtgaccgg cgtcggcttc accctcgaag gcatcctgcg
    15481 cgagtacttc tacctcgacg gccgccacca cgacggcgcg gtgtggggac tgctgcgcca
    15541 cgagtactac gcggcggtcg aggaactcaa gcgcaccgac gccacgttct cgctgccgga
    15601 cgccataccc gaggcggaca aggagcaggc ccgccggctc ctcgccgaat acatcgccag
    15661 tccgttcggc aagacgtcga cgggactcct cctcgccgcc gccggcgtcg ccccggtgga
    15721 ccgcgaccgg gaccgtacgc tcgagggcga ccgcctgccc ggggccgacg agcggtgacg
    15781 tcgcagcgct ggagcacgct ggtcctctca ccgcacttcg acgacgcggc cctctccgtc
    15841 gccggcctgc tcggccggct ggacggcccc gccgccgtgg tcaccgtcca cggcggcgct
    15901 ccgcccgagc gggcgcccgt ctcctggtgg gacgcgggct gcggattcgc cacggcgcgg
    15961 gaggcccacc gcgcgcgcct ggcggaggac gcgcgtgcct gcgccctgat gggggtggaa
    16021 cagctgaccc tgcccaacgc cgacagcccc taccgcgacg gcggccccct caccgggctg
    16081 agcgaactcc tgcgggagct gcacccggac accagggtgc tggtacccct cggcaccaac
    16141 cagccggacc acgcggccgt ccgcgaccag gccctcgccg ccctcaccga cccggcggga
    16201 ccccggccgt acgtgtacgc ggacctgccc tacacgggcg ccgtgcgccg gtggggcacg
    16261 gacgcggcgg tcgaacgcct gacccgcgac cccgcgtacg ggggcgcgct gcgcgagacc
    16321 gcggcccgat accggatgcg ggtggcgtac gacgtccgcc tcgacgacac cgaatgggcc
    16381 gccaagcgcg cggccatcgt ctgccacagc tcgcaactcg ccccggtggc cgtcggccac
    16441 ggccccttcc tgcgcaggcc cggccccctg caggccgaac tcgtctggga gctggagccg
    16501 ctcggcgacc ccaccgcaca cacccgggag ccctga
//
