LOCUS       reptomyces_RBGC_126917 16292 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_126917
VERSION     Streptomyces_RBGC_126917
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000721715.1
  ORGANISM  GCF_000721715.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..1224)
                     /protein_domains="PF07690"
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370145"
                     /pseudo=False
                     /translation="MRIDGYRKVVSRPGIGLLMLLGFFSKIAVVAIPVVMNLGVVFGLD
                     RGFGAAGLVIALWTVGVAIGGPVQGRMMDKYGVRPVLIVSLTGQALFWGIGPSMSYGVL
                     SVAAVGCGLLNLPGFAVVRLRLAVAIPEEQRHTAFALDAMTSNISYMVGPALGVTVATT
                     VSSDVSMRGLGLIVALAGAGLALLNPQVRDSAKETGSEPAPRMRFRQWFKPALVPVLVA
                     TTATTLATAGYETAIVGGLRDSGQVEWAGLVLTVCGFCSFIGALLYGTLKRPPHFALIS
                     ALVGLTTVVGGFATGDWRLLCLAMVLPAALCSPSFAATGGAASGLAPAGARGVVMGIYS
                     ASLTLGNSIGAPLSGAIQDARSPLWAFVVIGLTSAALSGVALGWTAWLARRPAAEPQNA
                     PVLADAAA*"
     CDS             complement(1274..2562)
                     /protein_domains="PF02655"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370146"
                     /pseudo=False
                     /translation="MRRIAFLRSIEIQQTKPFLTALEARLQREDTEAKLFYTDGECGPD
                     DFPGESEKIAGDISADELAKKVIGWGAHGVISLSIADENALRDSVVRRRLETVGIPMVA
                     HSLAATSLTANKWETKRLLEEHGFDIPPGVLVDSDVLAGRGLRIPAYVDSILIQTADMG
                     YPVLSKPLWDCMGAGMVPLADEAELERHLAEPHSGNFILERCVSGEICSVEVVGARGQY
                     VVHPVVWQGPAEIGPVFNFGRLRYVAPRREADLAFAPVAEKLKKLAQDLDLHGAVGLDM
                     IYEDGIYRILEINPRVTGTTTPCIASTGFNTYDCLLSILDGTWPDEADHGHGLQRVCLQ
                     FPVRELSPEFVRDLTRELDVVRTQSLNIDGVDHPNVIITCELDDRAELPAKLESLRQRH
                     EFTDRSFLRQIAAAVGVAVAEPAETAVATA*"
     CDS             2706..3757
                     /protein_domains="PF00196"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370147"
                     /pseudo=False
                     /translation="MARSGTQGGASALILEPGSLSVYEWALRNGGLRDADGAAAELGLS
                     ISELTLARDNLLELGLLVSSADGGELLPADPAIAEMLARAPLEQEIRQRQQELTRMHAQ
                     LRPLAPLFAEHSRAGRTSDGLRSFDDPAEVRRELSMMTRLCTEEMVSIQPGGGRDPDTL
                     SSIVAESLSMLERGVRLRTLYQHTARASLSTQAYVRSVSVAGARIRTTAEAFDRIIVFD
                     RETAFVPQPRAAGRPQGASVVTDPTVVGFLYRMFESLWESGRPFDAHQAEFQPSTEDLK
                     TSILRLMATGLKDEVIAKRLGMATRTFRRHVKDITDELGVESRFQAGFRAWQLGISLGE
                     GDDPGTSGTD*"
     CDS             4012..5060
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370148"
                     /pseudo=False
                     /translation="MYPAKPVVPIPSTKARATYVELLRKDSGAQSERERSDGPSECPAD
                     GVREDREIMDELLSMGMVREDTSSPSHFVAVEPGIVEARIGALLRSSALTMLEEARNLT
                     DLLRPLIVDSRHTAGPQGSESIVRIQGKAAISAIVNESVQQSTSELFTAQPGGGRPKAT
                     LEQIRQQTAELLDRGVEVRTLYQHTAWHDGPTREYVTEMTSLGAQVRTLDEFFDRLIIV
                     DRSMAFVPADTERDQAVIIREPAVVRFLTEVFERNWQRAKPFQGSRTPNESSHISAVLR
                     ETIIRCLIHGDSDNAIAKRIGLSTRAYATHLAKLKADLKAESRFQLGYRLGQLAGGGPT
                     PEAGETAGV*"
     CDS             complement(5210..6690)
                     /protein_domains="PF00860"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370149"
                     /pseudo=False
                     /translation="MKGTQSPSPVRRILGVGWRLHGDGRAPRPGAAVMPDERLSWPRTV
                     GLGAQHVVAMFGATFVFPVVMGLDPNLAIMMSGVSTVLFLLVVQGRIPSYLGTSASFVG
                     AVAAIRAAGGTTSTVTGAILVAGLVLAAVGLIVHFAGPGLINKAFPPVVAGAVVLLIGL
                     NLAPVVADIYWPQDQWVALATMCVVVVTGVLLRGFWSRLAVFVGLVFGYALSWVLDRTA
                     GPITAPGATGEVTRHLRVQLSEAASAPWFGLPTMHAPTFTASAALLVLPGVIALVAENT
                     GHIKAVAEMTGSDLDPVLGRAILGDGLATAVSSAVGGAPTTTFAENIGVMAATRVYSTA
                     AYWMAAATALLFGLCPKFGALVAATPGGVLGGITVVLYGMIGLLGAKIWIKSAVDFADP
                     VNLVPIAAGAVLGIGGVSIQVTDTFSVSGIALGTLVTLLGYHVLAALRRPAAESAAESR
                     PSLVAQPGVAAPRTPAPTDRLTPAPVQEPARSVGA*"
     CDS             complement(6806..8040)
                     /protein_domains="PF18603"
                     /protein_domains="PF13535"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370150"
                     /pseudo=False
                     /translation="MARAVLLLGAEGAVAEQLVGAAQTLEIHLHIATHRELYRSCPDEL
                     RKQLAGTVFTDFRSTAYAVDQLAEYCAQEGIGGVAVDRETLSPVAAALTDRLGLPGHDP
                     ATAQSARGRWQMAQTLRTRGVPGPRTVAVVSPEAAEERLRSAGLHYPVVVRPAEGSGSI
                     GLTLVETPDELPGAVRRALKWREDITYGIRFDAVAVIQEHLKGAEYSVETVLHRGGCTH
                     LAIVRRMSTGGRNSEELGRTLPADVDELTRITILATVERGLAALGLRDGIAHSHLKMTA
                     EGPRLIEVGAGPPDGPVMEMIEHATGVGVAAAYLQAVLGELPDTRPTRSGAVALRFINT
                     PRHGVFRGLSGLAASPHVIAVRSYAEPGDLVGSTHSKYTRLGHVIVLASGPDQADARAD
                     EAIAGISSCIES*"
     CDS             complement(8101..9149)
                     /protein_domains="PF14226"
                     /protein_domains="PF03171"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370151"
                     /pseudo=False
                     /translation="MSVLNVESAAPEAAQVTVVDGYVPVIDLSSARSGGAAEQQLAAVI
                     DEVCRTSGFLVIVGHGVPERTISEMYRATREFFALSAETKAELLAVPADPLMRGFGRQG
                     SLAASNAEAEVEQERALPDISETFTVNRLGEPDADRALPADADPALRTPNHWPELPGFT
                     EAYRSYYAAMEVLAGDIMRLFALALDLPEDWFEDKIEQHMTNLTANFYPQQPEPPAPGQ
                     LRKGMHSDWGSLTILYQDDGPGGLQVLDKAGQWLDVPVIEGSFVVNIGDLMAIWTNNRW
                     VSTVHRVVNPPRELAGKERYSVPFFHQPAYDALIECIPTCTGPLNPPRHEPVRSGDYII
                     GKFSRAYGA*"
     CDS             complement(9168..9727)
                     /protein_domains="PF03641"
                     /protein_domains="TIGR00730"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370152"
                     /pseudo=False
                     /translation="MRVTVYAGSALGNQAIYQEAAAAFAKQLVAEGHEIVYGGGAAGLM
                     GVVADSALAAGGRVTGVIPKHLVDAEVAHQGLTELHIVDTMHQRKQIMADLADAFVALP
                     GGVGTVEEILEAWAWLILGRHGKPMAMLNVDGYWDRLLRMICRMSASGFLREQELGTLA
                     SVGDANEFLDLVSQWEPPPPRWG*"
     CDS             complement(9759..10522)
                     /protein_domains="PF02511"
                     /protein_domains="TIGR02170"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370153"
                     /pseudo=False
                     /translation="MTISPALEVHAPDAPVFGPEIELRSQITVELVDHTASDLGVVRAA
                     RVSTAGEAAHREERGDAYIGGLIRYLMRSRHGSPFEHNSMTFLVHAPIFAIRHMMRHRM
                     WSFNEESARYKDLKNVFYVPDRDRALKQEGKPGHYQYVPGSEEDYELLSTATSEAYRSA
                     FREYQKMLDAGIARELARMVLPVATFSTVYATCNARSLMHFLGLRTNRADAAYVSHPQR
                     EIEVVAEQMEDEFARLMPLTHEAFEKFGRVSP*"
     CDS             complement(10588..10784)
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_4370154"
                     /pseudo=False
                     /translation="MRNNTFQMKLSATRRGIQSALVAAASAVLVATAVGVATAGSAVAD
                     TTTTTTTPSTSASPDDHGWD*"
     CDS             complement(10778..10974)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MSRSLEAPLPHCGSGASAWGACSCTWFRTYALHKSDLIGGRLISK
                     NGDVSGGAAHKQREEESNYA"
     CDS             complement(11007..11350)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370155"
                     /pseudo=False
                     /translation="LETNEHTLSAAALLETAHKAVSQGYPCDDRLARAALHLIECATDV
                     VVRLPDRDIDSAREALGLARAAVVTATCAVREIHAQARETSEPVSLPTPGKPPAGSARG
                     PGRVCCGLDR*"
     CDS             complement(11381..12624)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370156"
                     /pseudo=False
                     /translation="MSEPGKGALCHDLSAWNSGPVVHEEGSYDPAVARHCERIVHAPIA
                     DGPAILEVLRPLHEERPFDRVLTTTEPAAESTGYVVDAMGLTGVTEATARALKDKALTR
                     ELLANYDLSPVRHQVVHSAEEASGFQRSVGGRIVLKPVDGVAGLHIHPAANADEAARAW
                     RDLAADGYDAPIAEEYLEGPVASVDSFPFDGRHVPIGYSEYRMNERFGEWEVSTPSRAA
                     APHLAELPALTVQLLDAVGLTEGPSHSEFVLTPQDPRVLESHARLSGSGAPELVRCAFG
                     VDLNRWFLTVPLGIDELPAASPEPVGDAAVRFFTPQPGQVRAVEVATEVRRVPRGETPL
                     VFLLYLDEFRQLPAAAVIAKSPGDTVPEPLTVADCVSGYVIASGVDREAAVTRCEEIDK
                     NIRFLTDRRSDRPTN*"
     CDS             complement(12883..13229)
                     /protein_domains="PF00106"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370157"
                     /pseudo=False
                     /translation="MTPHSHEGSDRFRSLQLQACDPFEARPPGTESYWAAQPDGEDRGN
                     GRGQTTVGKAGMTRTAVVTGASSGIGAAVARRLAKDGFDTVLVARRGELVRRVAEETGG
                     PPPSTRGSTVR*"
     CDS             13313..13776
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370158"
                     /pseudo=False
                     /translation="MAEQRVTLTPQMLAYDDFDGRSRTRWLPYLMYFHRAGYRSDVVNT
                     REFGFRYSHGPGDGSASAGTVAQTGPVRPLTGSSTAFGIGARSDAATLPSRLWSAYAPS
                     APCLNFAGRSYNSGQEFTLFALCRHLLTRVTDIVVFSGLNNLALSPLPKE*"
     CDS             13944..14665
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370159"
                     /pseudo=False
                     /translation="MTHNPMPYRTAPQRTAPSDPATVPTEDPVEDTARTSRTGQRRTPG
                     ATTHHAAVDTRPHILVVHRWRDEHALYENYIDHTTHRVTYVTTELGWSSLPPAAAGVVE
                     VTATDDFDQVGAAAATLTALFGAPDRVVALNEGDLDTAAALRARPGLPGQPPQDLARFR
                     DKLVMCETVGAAGVRTPAFADAPDAAAVRAFADTHGWPVIVKPRRGTAGRGVLRIDSPA
                     GLSALDELPGEERLVQEL*"
     CDS             14706..15016
                     /protein_domains="PF02261"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370160"
                     /pseudo=False
                     /translation="LLWSGAVLSRLDDGDARRGAARPLARAGIGINGAAARLVSPGDLV
                     IIIAYGLYTREEALALRPSVVHVDGHNRVVHLLGTDSTEALVPGLTTSPSVARTAPGA*
                     "
     CDS             15158..15564
                     /protein_domains="PF03459"
                     /protein_domains="PF12728"
                     /protein_domains="TIGR00638"
                     /protein_domains="TIGR01764"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370161"
                     /pseudo=False
                     /translation="MLAHMQSYTIGQAARLLGVSPDTARRWADAGRVATHRDEGGRRLI
                     DGKDLAAFSVELAKTGSGEEDASYTSVRNAFPGIVTAVKLGDIAAQVEIQAGPHRLVSL
                     LTREAVEELGLEVGMEATARVKSTNVHIDRA*"
     CDS             complement(15817..16292)
                     /protein_domains="PF00174"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4370162"
                     /pseudo=False
                     /translation="VSRPFTERVADPVAELALTGDLASPARMTVSDLLAWPQHRVRVSF
                     ECATSGIQHHGFKGPLLHDVLSAAGPVFDPARRKDRLRFLIAVTGADGHHALLSWAEID
                     PDFGRAAVLLAVSIDDTPLDRAGPQLVLPQDRCGARHISGINAIRVDGGYTSWT*"
ORIGIN
        1 tcaggcggcg gcgtcggcga gtaccggtgc gttctgcggc tcggcggccg gcctgcgagc
       61 cagccaggcg gtccagccga gggcgacacc ggagagggcc gcgctggtga ggccgatgac
      121 cacgaaggcc cagagtgggc tcctggcgtc ctggatcgcc ccggacaggg gggcaccgat
      181 gctgttgcct agagtgaggg aggcgctgta gatgcccatc acgacgcctc gggccccggc
      241 cggggccagc ccgctcgcgg cgccgccggt cgccgcgaag gagggcgagc agagagcggc
      301 cggcagcacc atggccaggc acagcaggcg ccagtcgccg gtggcgaagc cgccgaccac
      361 ggtcgtgaga cccaccagtg ccgagatgag ggcgaagtgc ggtggccgtt tcagcgtgcc
      421 gtacaggagc gcaccgatga aggagcagaa cccgcagacc gtgaggacga ggccggccca
      481 ttcgacctgg cccgagtcgc gcaggccgcc cacgatcgcc gtctcgtagc cggcggtcgc
      541 cagagtggtg gcggtggtgg ccacgaggac cgggacgagc gcgggcttga accactggcg
      601 aaacctcatg cggggggccg gctcgctgcc ggtctccttg gcggagtcgc ggacctgggg
      661 gttgagcagg gccaggcccg ccccggcgag cgcgacgatc aggccgaggc cccgcatgga
      721 gacatcgctg gagacggtgg tcgccacggt caccccgagc gccgggccca ccatgtacga
      781 gatgttggac gtcatggcgt cgagcgcgaa ggcggtgtgc cgctgctcct ccgggatggc
      841 tacggcgagc ctcagccgca cgacggcgaa ccccgggagg ttgaggagtc cgcagccgac
      901 ggccgccacc gacagcaccc cgtaggacat gctggggccg atcccccaga agagcgcctg
      961 gccggtcagc gagacgatga gtacgggccg tacgccgtac ttgtccatca tgcggccctg
     1021 caccggaccg ccgatcgcca cgcccaccgt ccacagcgcg atcaccaggc cggcggcgcc
     1081 gaagcctcgg tcgaggccga acacgacgcc caggttcatc acgacgggga tcgccaccac
     1141 cgcgatcttc gagaagaacc cgaggagcat gagcagaccg atacctggcc ggctcacgac
     1201 cttgcgatag ccgtcaatcc gcatggctgc ctgccgtttc cttcatctct ttctcccaca
     1261 cttcggtttt cgtcatgccg ttgccacagc ggtctccgcc ggttccgcga cggccactcc
     1321 tacggccgcc gcgatctgcc gcaggaatga ccggtcggtg aattcgtggc gctgccggag
     1381 cgattcgagc ttcgccggga gttccgcccg gtcgtcgagc tcgcaggtga tgatcacatt
     1441 ggggtggtcg acgccatcga tattgagcga ctgcgtccgt acgacgtcca gttcgcgggt
     1501 caggtctcgc acgaattccg gggagagttc gcgcaccggg aactgcaggc acacccgctg
     1561 gaggccgtgc ccgtggtccg cctcgtccgg ccaggtaccg tccaggatcg agagcaggca
     1621 gtcgtacgtg ttgaagccgg tggaggctat gcagggggtg gtcgttccgg tgacccgggg
     1681 gttgatttcg agaatccggt agatcccgtc ctcgtaaatc atgtccagcc cgaccgctcc
     1741 gtgcagatcc aggtcctgag cgagcttctt gagtttctcg gccaccgggg cgaatgccag
     1801 atccgcctcc cggcgcggtg ccacatagcg cagtcggccg aagttgaaga cggggccgat
     1861 ctcggccggc ccctgccaca ccaccgggtg gaccacgtac tgtccgcggg cgccgaccac
     1921 ttccaccgag cagatctcac cggacacaca gcgttccagg atgaagtttc cgctgtgcgg
     1981 ttcggccagg tgccgctcca gttccgcttc gtcggccagc ggcaccatgc cggcacccat
     2041 gcagtcccag agcggcttgc tgagcacggg atatcccatg tcggcggtct ggatcaggat
     2101 cgagtcgacg tacgcgggaa tgcgcaggcc acggccggcg agtacatcgc tgtccacgag
     2161 cactccgggc ggaatgtcga atccgtgctc ctccagcagc cgcttcgtct cccacttgtt
     2221 ggcggtgagg ctggtggcgg cgaggctgtg cgccaccatg ggaattccca cggtctccag
     2281 gcggcgccgc accaccgagt cacgcagggc gttctcgtcc gcgatggaga gggagatcac
     2341 tccgtgggcg ccccagccta tgaccttctt ggcgagttcg tcggcggata tgtcaccggc
     2401 tatcttctcc gattcaccgg ggaagtcatc gggtccgcac tcgccgtccg tgtagaagag
     2461 tttcgcttcg gtgtcctccc gctgaagacg tgcctcaagg gctgtgagaa aaggctttgt
     2521 ctgctgaatc tcaatggatc gcaggaatgc gattcggcgc attgcttcac ccttccgggg
     2581 aacctcggtc gttcagatcg accgtgctgt acagcgcgat atgaagactt tgccagcaac
     2641 aacggcccag ttggagagat actcggtgtc ctaagctggc cagaccggaa gaggatctcg
     2701 acaaatggcg cgttcaggga cacaaggcgg cgcctcggcg ctcattctcg agccaggctc
     2761 gctgtccgtc tatgaatggg cgctgcggaa cggcgggctc cgcgacgcgg acggcgctgc
     2821 ggccgaattg ggcctgtcca taagcgagtt gactcttgcg cgcgacaacc tactggaact
     2881 cgggttgctt gtgtccagtg ccgacggcgg cgaactgctg ccggcggacc cggcgatcgc
     2941 cgagatgctt gcgcgggcac cgttggagca ggagatccgg cagcggcagc aggagctgac
     3001 ccgcatgcac gcccaacttc ggcctctggc gccactgttc gcggagcaca gtcgcgccgg
     3061 gcgcacctcg gacgggctgc gctccttcga cgatcccgcc gaggtgcgcc gcgagttgtc
     3121 gatgatgacc cggctgtgca ccgaggagat ggtctccatc cagccgggcg gcggccgcga
     3181 ccccgacacg ctgagctcga tcgtcgcgga gagtctgtcg atgctggaga gaggggtgcg
     3241 gctgcgcacc ctctaccagc acaccgcccg ggcgagcctg tcgacgcagg cctatgtgcg
     3301 gtcggtctcc gtggccgggg cccggatccg caccaccgcc gaggcgttcg accggatcat
     3361 cgtcttcgac cgggagacgg cgttcgtccc gcagccccgg gccgcgggcc ggccgcaggg
     3421 ggcctcggtg gtcaccgacc cgacggtggt gggtttcctg taccggatgt tcgagagcct
     3481 ctgggagtcg ggccggccct ttgacgccca tcaggccgaa ttccagccat ccactgagga
     3541 cttgaagacc tcgatcctgc gcctgatggc gaccggcctg aaggacgagg tgattgccaa
     3601 gcggctgggg atggcgacgc ggaccttccg ccggcacgtg aaggacatca ccgacgagct
     3661 gggggtggag agccgcttcc aagccgggtt ccgcgcttgg caattgggga tttcgctggg
     3721 agaaggcgac gatcccggca catccgggac ggattgacgc gtctgcggtt ccgggtgggc
     3781 cggcgggtca cggcttcccc gccggccggc atccgacggc tatttgacat ctctgtgaaa
     3841 taggcgcgtt ctgttcaccg ctcagcggac gaacaggcac aatgcccatg cagcaggcac
     3901 acaaccctgc tctgtcggcg gcggattcgg ctcactatcg gcactcggcc catgggagct
     3961 acactccgcc tccttctgcg tgatcaccaa tactctcaac ggagttggct atgtatccgg
     4021 caaagccagt ggtgcccata cccagcacga aggcgcgcgc cacgtacgtc gaactcctcc
     4081 ggaaggactc gggtgcgcag tccgagcggg agcggtcgga cggcccgtcg gagtgccccg
     4141 cggacggcgt ccgcgaggat cgcgagatca tggatgagct cctgtccatg gggatggtcc
     4201 gcgaggacac ctcctccccc tcgcacttcg tcgcggtgga gcccggcatc gtggaggcac
     4261 ggatcggagc gctgctgcgt tcttccgcgt tgaccatgct ggaggaggct cggaacctca
     4321 cggacctgct acgacccctc atcgtcgact cccggcacac cgcgggacca cagggcagcg
     4381 agtccatcgt ccgcatccag ggcaaggccg cgatcagcgc catcgtcaac gagagtgtgc
     4441 agcagagcac gtcggagctg ttcaccgccc agcccggggg cggccggccc aaggccacgc
     4501 tcgagcagat acgtcagcag accgccgagc tgctcgaccg cggggtggag gtgcggacgc
     4561 tctaccagca caccgcctgg catgacgggc ccacccgtga atacgtgacc gaaatgacgt
     4621 cgctgggcgc ccaggtccgt actctcgacg agttcttcga ccggttgatc atcgtcgacc
     4681 ggagcatggc attcgtccct gccgacaccg agcgggacca ggccgtcatt atcagggaac
     4741 cggccgtggt gcgattcctc accgaggtct tcgagcgcaa ctggcagcgc gccaagccct
     4801 ttcagggatc tcggactccg aatgaatcga gccatatcag tgccgtgttg cgcgagacca
     4861 ttatcaggtg cctcatccat ggggacagcg acaatgccat cgccaagcgg atcgggctca
     4921 gcacccgcgc ctacgccacc cacctggcca aactcaaggc cgatctcaaa gccgagagcc
     4981 gcttccagct cggataccga ctgggtcagt tggccggtgg cggcccgact cccgaggcag
     5041 gcgaaacagc cggggtgtga agtgatcctg ggatcacttc acaccccggc tgcaggtgcg
     5101 ccgtagcgac agctggtcga tgagcctcgc cgacctggtc cagggcctct cgttcggatc
     5161 aggctggact cgtgttgggg tccggcacgc acatctgccg cgttgtcgtc aggcgccgac
     5221 gctccgcgcg ggctcctgga ccggggccgg ggtgagccgg tcggtgggag ccggcgtcct
     5281 gggcgcggca acgcctggtt gcgcgaccag gctcggacgg gactccgcag ccgactcggc
     5341 ggcaggacgc cgcagggccg ccaggacgtg gtaaccgagg agggtgacga gggtgcccag
     5401 ggctatgccg ctgaccgaga aggtgtccgt cacctggatc gagacccctc cgatgcccag
     5461 caccgcgccg gctgcgatcg ggaccaggtt caccgggtcc gcgaagtcca ccgccgactt
     5521 gatccagatc ttggcgccga gcagcccgat catcccgtac aggacgacgg tgatgccccc
     5581 gaggacacca cccggggtgg ccgcgacgag cgcgccgaac ttggggcaca ggccgaacag
     5641 cagagccgtg gcggccgcca tccagtacgc ggcggtcgag tagacccggg tcgcggccat
     5701 caccccgatg ttctccgcga aggtcgtggt cggcgcgccg ccgaccgccg aggagaccgc
     5761 cgtggccagt ccgtcgccga ggatggcgcg cccgagcacc gggtcgaggt cggaacccgt
     5821 catctcggcc accgccttga tgtgcccggt gttctccgcc accagcgcga tcacgcccgg
     5881 cagcaccagg agcgcggcgg acgcggtgaa cgtcggtgcg tgcatggtcg gcaggccgaa
     5941 ccacggggcc gatgcggcct ccgagagctg cacccgcaga tggcgggtga cctcgccggt
     6001 ggcgccgggc gcggtgatcg ggcccgccgt ccggtccagc acccatgaaa gggcgtatcc
     6061 gaagaccaga ccgacgaaga ccgcgagcct gctccagaat ccgcgcagca gcacgcccgt
     6121 gacgacgacc acgcacatgg tcgcgagagc cacccactgg tcctggggcc agtagatgtc
     6181 ggccaccacc ggcgccaggt tgagcccgat gagcaggacc accgcgccgg ccacgacggg
     6241 cgggaacgct ttgttgatca gtccgggccc ggcgaagtgg acgatcaggc ccaccgcggc
     6301 gagcaccagc cccgcgacga ggatcgcgcc ggtgacggtg gacgtggtgc cgccggccgc
     6361 ccggatggcc gccaccgcgc cgacgaacga ggcactggtg ccgaggtagc tggggatccg
     6421 gccctgaacc accagcagaa acagaacggt cgagactccg gacatcatga tggccaggtt
     6481 cgggtcgagc cccatgacca ccggaaagac gaatgtcgca ccgaacatcg ccactacgtg
     6541 ctgggctccg aggcccaccg tgcgcggcca ggagagccgc tcgtccggca tcaccgcggc
     6601 gcccggtcgc ggtgcccggc cgtcgccgtg cagtcgccat ccgacaccga ggatccggcg
     6661 taccggactc ggactctgtg ttcccttcat ggttctcgtt cctccggtca tgggcaggcc
     6721 gccgcaccgc cgtggcggcg gtgcggcggt gccgttcaag gggtgggtgt ggagaggggg
     6781 ccagccggtc tctccgggcg gggctcagct ttcgatgcag ctggagatgc ccgcgatggc
     6841 ctcgtcggcg cgggcgtcgg cctggtccgg tccggaagcc aggacgatga cgtggcccag
     6901 acgggtgtac ttggagtggg tgctgcccac caggtcgccc ggctccgcgt aggagcggac
     6961 ggcgatgacg tgcggactgg cggcgaggcc gctcagaccg cggaagacac cgtgccgagg
     7021 ggtgttgatg aaccggagcg ccaccgcacc gctgcgggtc ggccgggtgt cgggcagctc
     7081 gccgaggacg gcctggagat aggccgcggc cacgccgacc ccggtggcgt gctcgatcat
     7141 ctccatgacg ggtccgtcgg gcgggcccgc gcccacctcg atgagccggg gaccctctgc
     7201 cgtcatcttc agatggctgt gcgcgatgcc gtcccgcagt ccgagggccg cgagcccgcg
     7261 ctccacggtg gccaggatcg tgatccgggt cagctcgtcc acgtcggcgg gcagagtgcg
     7321 cccgagctcc tcgctgttcc ggccgccggt ggacatccgg cggacgatcg ccaggtgcgt
     7381 gcagccgccg cggtgcagca cggtctccac gctgtactcg gcgcctttca ggtgctcctg
     7441 gatcaccgcg acggcgtcga agcggattcc gtaggtgatg tcctcgcgcc atttcagggc
     7501 gcgccggacc gctccgggca gctcgtccgg cgtctcgacg agagtcagcc cgatgctgcc
     7561 cgagccctcg gccggtctga cgacgaccgg gtagtggagg ccggccgacc gcagccgctc
     7621 ctcggcggcc tcgggggaga cgaccgcaac cgtgcgcggc ccgggtacgc cacgcgtgcg
     7681 cagggtctgc gccatctgcc acctgccgcg ggcggactgt gccgtggctg gatcatggcc
     7741 aggcagtccc agccggtcgg tcagcgctgc ggcgaccggg gacagcgtct cccggtcgac
     7801 cgccactccg ccgatgcctt cctgggcgca gtactcggcg agttggtcga ccgcgtaggc
     7861 cgtgctgcgg aagtcggtga agacggttcc ggcgagctgc ttgcgcagtt cgtcgggaca
     7921 gctccggtac aactcccggt gggtcgcgat gtgcaggtgg atctcgaggg tctgggccgc
     7981 tcccaccagt tgctcggcca cggcgccttc ggcacccagc agcagaaccg ctctggccat
     8041 ggtgttctca cctcgctttc gacggcatct cgtagttcgc ggaactcttc gccccggact
     8101 tacgcgccat acgctctgct gaacttaccg atgatgtagt cgcccgagcg caccggttcg
     8161 tgcctcggtg gattgagcgg accggtgcag gtggggatgc actcgatgag ggcgtcgtag
     8221 gccggctggt ggaagaaggg aaccgagtag cgttcctttc cagccagttc acgcggcgga
     8281 ttgaccaccc ggtggacggt gctcacccac cgattattgg tccaaatggc catcaggtca
     8341 ccgatgttga caacaaagga accctcgatg acgggcacgt cgagccactg acccgccttg
     8401 tcgaggacct ggaggccgcc cgggccgtcg tcctggtaga ggatggtcag gctgccccag
     8461 tcgctgtgca ttcccttgcg gagctgcccg ggtgcggggg gttccggctg ctgcgggtag
     8521 aagttggcgg tcaggttggt catgtgctgc tcgatcttgt cctcgaacca gtcctcgggc
     8581 agatcgagcg caagggcgaa cagtcgcatg atgtccccgg ccagcacctc catggccgcg
     8641 tagtaggacc ggtacgcctc ggtgaagccg ggcagttcgg gccagtggtt cggggtccgc
     8701 agagccgggt cggcgtcggc gggcagcgcc cggtcggcat ccggctctcc cagacggttg
     8761 accgtgaagg tctccgagat gtccggcagt gcccgctcct gctcgacctc ggcctccgcg
     8821 ttggaggccg cgagactgcc ctggcggccg aatccccgca tcagcgggtc ggccgggacg
     8881 gcgagcagtt ccgccttggt ctcggccgac agcgcgaaga actcccgggt ggcccggtac
     8941 atctccgata tcgtgcgctc gggcacaccg tggccgacga tcaccaggaa gccgctggta
     9001 cggcagacct cgtcgatcac cgcggccagt tgctgttccg ccgccccgcc cgaccgtgcg
     9061 gaactcaggt cgatcaccgg gacatagccg tccaccacgg tgacctgcgc ggcctcgggg
     9121 gccgcactct ccacattcag taccgacatc gctcctactc ccgatctcag ccccatcgcg
     9181 gcggcggggg ctcccactgg cttacaaggt cgaggaattc gttcgcgtcc ccgacggacg
     9241 cgagggtgcc cagctcctgc tcgcgcagga atccgctggc ggacatgcgg cagatcatcc
     9301 gcaggagccg gtcccagtag ccgtccacgt tcagcatcgc catcggcttt ccgtgccggc
     9361 cgaggatgag ccaggcccag gcttcgagga tctcctcgac ggtgcccacc ccgcccggca
     9421 gcgccacgaa ggcatccgcc aggtcggcca tgatctgctt gcgttggtgc atggtgtcga
     9481 cgatgtgcag ttcggtcagg ccctggtggg cgacctcggc gtcgacgagg tgtttcggga
     9541 tcactccggt gacccggccg ccggccgcca gggcggagtc ggcgacgacc cccatgaggc
     9601 cggccgctcc cccgccgtag acgatctcgt gcccctcggc gacgagttgc ttggcgaagg
     9661 ccgcggcggc ttcttggtag atggcctggt tccccagggc cgagcccgcg tagaccgtga
     9721 ctctcatggc aggaacctcc gtcggatcgc gatccggtca gggactgacg cgtccgaact
     9781 tctcgaaggc ctcgtgggtc agcggcatca gccgcgcgaa ctcgtcctcc atctgctcgg
     9841 ccaccacctc gatctcccgc tgcgggtgcg acacataggc ggcgtcggcg cggttggtac
     9901 gcaggccgag gaagtgcatc agcgagcggg cgttgcaggt ggcgtacacg gtggagaagg
     9961 tggccaccgg gagcaccatg cgggccagct cgcgggcgat tccggcatcg agcatcttct
    10021 ggtattcgcg gaaggcggac cggtaggcct cgctggtggc ggtggagagc agctcgtagt
    10081 cctcctcact gcccggaacg tactggtagt gaccgggctt cccctcctgt ttcagcgccc
    10141 ggtcgcggtc gggcacgtaa aagacgttct tgaggtcctt gtagcgggcg ctctcctcat
    10201 tgaaggacca cattcggtga cgcatcatgt ggcggatcgc gaagatcggc gcgtgcacca
    10261 ggaaggtcat cgaattgtgc tcgaaagggc tgccgtgacg gctgcgcatc aaataccgga
    10321 tgagaccccc gatatatgcg tcaccgcgct cctcgcggtg cgccgcctcg ccggcggtgg
    10381 agacccgcgc cgcacgtacg actcccaggt cggaggcggt gtggtcgacg agctcgacgg
    10441 tgatctggct gcgcagttcg atttcgggac cgaagacggg tgcgtcgggg gcgtggacct
    10501 caagggccgg gctgatcgtc atcgtacgtt cctccggtgg attctgttca gcggtgctcg
    10561 atattgtgct gatggaatat gcctgttcag tcccagccgt gatcgtcggg cgaggcgctc
    10621 gtgctggggg tggtcgtcgt agtggtcgtg tcggccaccg cggaaccggc ggtcgccacg
    10681 cccaccgcag tggcgacgag taccgccgaa gcggcagcga ccagggcgga ctgaatcccg
    10741 cggcgagtgg ccgaaagctt catctggaac gtgttgttac gcataattcg attcctcttc
    10801 tcgttgtttg tgggcggctc ccccgctcac atctccattc ttcgaaatca ggcggccccc
    10861 aataaggtca gacttgtgca gtgcgtaagt acgaaaccaa gtgcacgaac atgcgcccca
    10921 tgccgaagcc ccgctgccgc agtgcggcag cggggcttcg agagaccggg acagggctcc
    10981 tgacctgggc ggaacggtcg tccgcctacc ggtcgaggcc gcagcagacc cggcccggac
    11041 cacgcgcgga cccggccggc ggcttcccgg gagtgggcag ggacaccggc tcggacgtct
    11101 cccgggcctg ggcgtggatc tcccgtacgg cacaggtcgc ggtcaccacc gccgcgcggg
    11161 ccagtccgag cgcctcccgc gccgagtcga tgtcacggtc gggcagtcgt acgacgacgt
    11221 ccgtggcgca ctcgatgagg tgcagcgcgg cgcgggccag ccggtcgtcg cagggatagc
    11281 cctgcgagac ggccttgtgg gcggtctcca ggagcgcggc agcgctcagg gtgtgctcgt
    11341 tggtttccaa ctctcttctc cttcgatggt gtgggccgat cagttcgtcg gtcggtcact
    11401 tcgtcggtcg gtcaggaagc ggatgttttt gtcgatctcc tcgcaccggg tgaccgcggc
    11461 ctcccggtcc acgccggacg cgatcacata tccggacacg cagtcggcga cggtgagcgg
    11521 ctccggaacg gtgtcgcccg ggctcttggc gatgaccgcc gcggccggca gctgcctgaa
    11581 ctcgtcgagg tacagcagga agaccagcgg tgtctcccct cgcgggaccc gcctcacctc
    11641 ggtggccacc tcgaccgcgc ggacctgtcc cggctgcggg gtgaagaacc gcaccgcggc
    11701 gtcgccgacc ggctcgggag aggcggcggg cagctcgtcg atgccgagcg ggacggtgag
    11761 gaaccagcgg ttcagatcca cgccgaaggc acaccgcacc agttcgggcg ccccgctgcc
    11821 ggacagccgg gcatgcgatt cgagcacccg ggggtcctgc ggagtcagga cgaactcgct
    11881 gtgcgagggt ccttcggtga gccctacggc gtcgagcagc tgcacggtga gcgcgggcag
    11941 ctcggccagg tgcggggcgg ccgcccggct cggggtactg acctcccact ccccgaagcg
    12001 ctcgttcatc cggtactcgg agtacccgat gggcacgtgc cgtccgtcga acgggaacga
    12061 gtcgacgctg gcgaccgggc cttcgaggta ctcctccgcg atgggcgcgt cgtagccgtc
    12121 ggcggcgagg tcgcgccagg cccgcgcggc ctcgtcggca ttcgcggccg ggtggatgtg
    12181 caggccggcg acgccgtcga ccggcttgag aacgatgcgg ccgccgaccg accgctggaa
    12241 cccggacgcc tcctcggcgc tgtgcaccac ctggtgacgg accgggctga ggtcgtagtt
    12301 ggcgagcagc tcgcgggtga gcgccttgtc cttgagggcc ctggccgtcg cttcggtgac
    12361 cccggtgagt cccatcgcgt cgacgacgta tccggtggac tccgcggcgg gctccgtggt
    12421 ggtcagcacc cggtcgaacg gccgctcctc gtgcagcgga cgcagcacct ccaggatcgc
    12481 gggcccgtcg gctatcggtg cgtgcacgat gcgttcgcag tgccgcgcga cggcgggatc
    12541 gtaagagccc tcctcgtgca cgaccgggcc ggaattccac gcagaaaggt catggcagag
    12601 agcccctttt cctggttcgg acatcactgg tccggacatc actgggttga acgtcaccgg
    12661 tctcggacgt caccggtctc ggacgtcgcc gggtgccggt gccggcagat cgccgggcgg
    12721 gcaggcgcga aggagtgccc gggctcagcc ggcgaagaga ccgcctcggt ggatcttgtg
    12781 ctgggccgcc tgggcgagcg ggcgcaccac cagctggtcg atgttgacgt gctgcggcag
    12841 cccgaccgcg aaggagacgc attcggcgac gtcctcggcg ctcagcggac ggtcgacccc
    12901 cgcgtagacg gcggcggccc gcccgtctcc tcggcgaccc gccggaccaa ctcgccccgc
    12961 cgggccacca gtacggtgtc gaacccgtcc ttggcgaggc gtcgggcgac agccgcgccg
    13021 atcccgctgc tcgccccggt caccacagct gttctggtca tgccggcctt ccccacagtc
    13081 gtctgtccgc ggccgttccc gcggtcctct ccgtcgggct gtgctgccca gtacgactct
    13141 gtgccgggtg gtcgggcctc gaaagggtca caagcttgca gctgcaggga tctgaaccgg
    13201 tcgctgcctt catgactgtg cggcgtcata tttctgatgg ttccgatcct ccggggccga
    13261 cggaagagtc acctccgacc gaggaggacc cttcacgaac cgggaggaac catggcggag
    13321 cagagggtga cgctcacccc gcagatgttg gcctacgacg atttcgacgg ccggtcccgg
    13381 acccgatggc ttccgtacct gatgtacttc caccgcgccg gctaccggtc cgatgtcgtc
    13441 aacacccgtg aattcgggtt ccgttactcc catggccccg gcgacgggag cgcgtcggcg
    13501 ggcaccgtcg cgcagacggg acctgtccgg ccgctcaccg gcagctccac agcattcggc
    13561 atcggtgcgc ggagcgatgc ggcgaccctg ccctcccgcc tgtggagcgc ttacgcgccg
    13621 tcggcgccgt gcctcaactt cgcgggccgc agctacaact cggggcagga attcacgctg
    13681 ttcgccctct gccgccacct gctgacccgc gtcaccgaca tcgtggtctt ctccggcctc
    13741 aacaacctcg cgctctcccc gctgccgaag gagtagcgca gtgaccacgg tggcttcttc
    13801 aactgcggtg agtactacga gcagatggaa gagctacggc agcggcgccg cgcccccgcg
    13861 ccgcgattcg ggcggcgcgg ccggagagcc gcgggcgccg cgccggcatc cgcataagag
    13921 accgaagaga caggtgcctg acatgaccca caacccgatg ccataccgga ccgccccgca
    13981 gcggaccgcc ccgagcgatc cggcaaccgt cccgacagag gatccggtcg aggacaccgc
    14041 ccgcacgagc cgtacgggac agcggcgcac gcccggcgcc accacccacc acgcagccgt
    14101 cgacacccgc ccgcacatct tggtcgtgca ccgctggcgc gacgagcacg ccctctacga
    14161 gaactacatc gaccacacca cccaccgggt cacctacgtc accacggagc tcggctggtc
    14221 ctcgctgccg cctgccgccg ccggcgtcgt cgaggtcacc gccaccgacg acttcgacca
    14281 ggtcggcgct gcggccgcga cactgaccgc actcttcggc gccccggacc gggtggtcgc
    14341 gctcaacgag ggcgacctcg acaccgccgc cgctctccgc gcccgtccgg gcctgcccgg
    14401 ccagccccct caggacctgg cgaggttccg ggacaagctg gtgatgtgcg agacggtcgg
    14461 cgcggccggt gtccgcacgc ccgccttcgc cgacgccccg gacgccgccg ccgtgcgcgc
    14521 cttcgcggac acccacggct ggcccgtcat cgtcaaaccc cgccgcggca cggccggtcg
    14581 gggagtgctg cgcatcgact cccccgccgg cctgtccgcg ctggacgaac tgcccggcga
    14641 ggaacggctg gtgcaggagt tgtgaaggcc tgtccgacgc cgctgcggct tcgggactac
    14701 cgccttgctg tggtccgggg cggtgctgag ccggctcgac gacggtgacg ctcgccgcgg
    14761 cgctgcccgg cccctggctc gtgcgggaat cggcatcaac ggcgccgccg cccgcctggt
    14821 ctcccccggc gacctggtga tcatcatcgc gtacggcctc tacacccgcg aggaggccct
    14881 ggcgctgcgc cccagcgtgg tccacgtgga cgggcacaac cgtgtggtcc acctcctcgg
    14941 caccgactcc acggaggccc tcgtcccggg cctgaccacc agcccgtcgg tcgcccgcac
    15001 ggctccgggg gcctgatgga cacggggtgg gtcccacgga ggggccggtt cccggggccc
    15061 cgacggggcg gatcactgct cggcgacgac gccgcagatc cggcgcgcga ccggcgcgtc
    15121 ccgggccctg tttgggtccc gcgggtgagt gcacctatgt tggcgcacat gcagtcctac
    15181 acgatcggcc aggccgcccg gttgctgggc gtgagccccg acaccgcacg gcggtgggcg
    15241 gatgccggcc gggtggcgac ccaccgggac gagggcgggc ggcggctcat cgacggcaag
    15301 gatctggccg ccttctccgt ggagctcgcc aagaccggga gtggcgagga ggacgcctcg
    15361 tacacctcgg tccgcaacgc cttccccggc atcgtcaccg ccgtgaagct cggcgacatc
    15421 gcggcgcagg tggagatcca ggccggtccg caccgactgg tctcgctgct gacccgggag
    15481 gccgtggagg agctgggcct tgaggtcggc atggaggcca ccgcccgggt gaagtcgacg
    15541 aacgtgcaca tcgaccgcgc ctgacgcccc gtgttcgggc ggctcccgtg gaccacgccg
    15601 tcacgaagcg gaggagcccc cgcggacgtg acgggcggcc gcccgggcga aacgccgctc
    15661 acgggcgagc gcgaccaggt gctccggccg gcccggcggc ctgcgccgcc cggccggccc
    15721 gcctcctgcg gtacgggctc cgcgaccagg acgcccaccg gcccggttcg ccgagcaccg
    15781 cgcgccacgt ccacgagccg agccctctcg cggtgtcacg tccacgacgt gtaaccaccg
    15841 tccacgcgta tcgcgttgat gccgctgatg tgccgggccc cgcagcggtc ctgaggcagc
    15901 acgagctgag gtccggcacg gtcgagcggg gtgtcgtcga tgctgaccgc gagcaggacg
    15961 gcggcacggc cgaagtccgg gtcgatctcc gcccaggaga ggagggcgtg gtggccgtcc
    16021 gcgcccgtca cggcgatcag gaagcgaagg cggtccttgc gccgggccgg gtcgaagacg
    16081 gggccggcgg cggacaggac gtcgtgcagc agcggtccct tgaagccgtg atgctggatg
    16141 ccgctggtgg cgcactcgaa gctgacccgc acgcggtgct gaggccaggc gagcaggtcg
    16201 gacacagtca tccgggccgg gctcgcaaga tccccggtca gggcgagttc cgccaccgga
    16261 tcggcaacgc gttccgtaaa gggccggctc ac
//
