LOCUS       reptomyces_RBGC_127225 16555 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_127225
VERSION     Streptomyces_RBGC_127225
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001941285.1
  ORGANISM  GCF_001941285.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..783)
                     /protein_domains="PF00528"
                     /protein_domains="TIGR03226"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540771"
                     /pseudo=False
                     /translation="MTRRLLWTLPPVALLAVFFLYPLALVVQQSFQPDSGGTSLQPYTD
                     VFASEAFRQALWTTVWLALASTAGCLVLGFFLALVIAFVPFPGARAVARFVDVFLSFPS
                     FLITLALLFIYGTTGIVGSFQFLTTPWGVLLAEVTYFTPFVMRPLLAAFSQLDTAQIEA
                     ASSLGARAPRIVRRVILPEALPALAAGGSLVLVLCLNEFGIVLFTGAKGVTTLPLLIYS
                     KAILESDYAGACVVAVVNVALSVGLYAVYRVVSRRAGA*"
     CDS             complement(777..1798)
                     /protein_domains="PF00005"
                     /protein_domains="PF08402"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540772"
                     /pseudo=False
                     /translation="VIRFDSVSVAYDGNTVLDALDLTVEPGEVIALLGPSGSGKTTALR
                     AVAGFVRPSAGRVFLGERDVTDVPPYRRGIGMVVQQYALFPHMRVEDNVAFGLKARRVN
                     KGEIRQRVGEALELTGMGAYARRRPRELSGGQQQRVAIARALAIRPEVLLLDEPLSALD
                     ARLRSEMLTELARLHRELPDMTILYVTHDHVEALTLADRIAVLDRARLQACGTPRELYR
                     APGDEFTASFVGGANLLPVQVTDGVAEFAGTRMKVDAKDVTGPATLCVRPHLVGLGEGP
                     NQLTGPVREIQWRGATHRLYVEVAGHTVMADVRELRDPPVHGARVTLHFSPEDAVLLHD
                     *"
     CDS             complement(1796..2475)
                     /protein_domains="PF13419"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540773"
                     /pseudo=False
                     /translation="MTTDMPHDIRLVVLDMAGTTVADGGLVERAFTTALGSLGLDPTPD
                     RLAYVRTTMGESKISVFRHLLQTEETAQRANTAFEQAYGDLVADGLIAPVPGAREAIEQ
                     LAAEGRTVVLTTGFARVTQDAILDALGWRDLVALTLCPADAGGRGRPYPDMVLEAFVRT
                     KAAEGVRQVAVVGDTSYDVLSGVRAGAGVVAGVLTGAHDAEALRAAGAGHVLGSVAELP
                     GVLT*"
     CDS             complement(2482..3605)
                     /protein_domains="PF01266"
                     /protein_domains="TIGR03364"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540774"
                     /pseudo=False
                     /translation="VRVIVVGAGVVGTLHAWQALERGHEVVQIEREAEARGASLRNFGL
                     VWVSGRADGEELSAALRARELWEGIGERVPALGFRANGSLTVVRGGLEHAVAEYAAARG
                     DADVRGYELLTPGEARALNPALRGEFGAALYCARDAAVEPRTAQRALRAELLRNPRYTF
                     LPGREVREVIGEHAVRDDHGDVHTGDAVVLCTGAWLGGLVRELAGPELPVRRVRLQMMQ
                     TAPLGEPLTTSVADADSFRYYPAYASPALDALNSRQPQPDTAAEHRMQLLMVQRADGGL
                     TVGDTHEYEHPFSFDTVEDPYEHLTGVVESLLGRPLPAIRRRWAGVYAQCLDTSRVVHR
                     QQVRDGVWLVTGPGGRGMTCAPAIAETTADQLGW*"
     CDS             complement(3746..4569)
                     /protein_domains="PF07702"
                     /protein_domains="PF00392"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540775"
                     /pseudo=False
                     /translation="MMQQGAVRPSYDGVAAGSVYGPPVDYPNDQHPGAPVRAGVPEHGR
                     VPKYYAVKARIDDLVSDLGEGAVIPTERDLSERYDVARETVRQALRELLLEGKLRRQGR
                     GTVVAGPKLEQPLALASYTEGVRRQGRTPGRSLVALDRFPCPAPLAEETGLTRGEPVWH
                     LERVLLADDERVGLESTYVSVARLPRLDAEFDPDSSFYAYMGGQGIRLGQADERIETVL
                     ATPREALLIGTPPALPMLLIHRVSRDAEGSPLERVRSLYRGDRFSFSAHLKN*"
     CDS             4613..5805
                     /protein_domains="PF00067"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540776"
                     /pseudo=False
                     /translation="MTELRLPLPAEGPLEPPAAWADLRRECPVASVRLPSGDEATLLTR
                     YDDIRTLLSDPRFARPAAEDGAARLAPEGAGGPVVDGELQDVIPDRGEGHQRWRRQVGK
                     YFTAKRMTALRPAITERADRLVDSMVEQRQPADLKGAFGFPLPVYVICTILGVPAEDSD
                     RFSHWSDAFLNVSRWTKEESAAAYEEFDAYMSRHITHVREHPGDDLISMLIADQPDVTD
                     TWLLRTGMGLLVAGHETTANAIGKTVAMLLADRELWELLLAEPELVRTTVDEALRLDVN
                     LGFGLRRYLTEDVEVGGSVLPRGATVVCALPAANRDAAAFEDPDLMLLSRSPNPHLAFG
                     AGPHACLGQSLARTELQVALEVLLRRLPALRLAVPVGELRRLEGLLVGGLSEVPVTW*"
     CDS             5803..6014
                     /protein_domains="PF13459"
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_1540777"
                     /pseudo=False
                     /translation="VRVAVDRSLCCGAGNCVLVAPGVFDQDEDDGVVVLLTETPASSDE
                     AATREAAAMCPASAITLRDDMYRDA*"
     CDS             6071..7452
                     /protein_domains="PF07995"
                     /protein_domains="TIGR03606"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540778"
                     /pseudo=False
                     /translation="MRKLPSALALAAVAALVCSCGSGSATGTVQRAAAVNLDAKAGFTV
                     VTTGLGDPYEMIQGPDGYLWLTEKSGLKVTRVDPKTGAKTTALDLAKKAVRAKGGKDGV
                     LGLALHPDFGKKKDKDYVYLSYSSMDGVKEATRIVRYTAKNGKLSGEYTVLSGLPAGDD
                     HQAARLRYGPDGKLYYSIGDQGANYYAHYCVPNQAQNLPTADQVKKKDWSVYPGKILRM
                     NPDGSIPDDNPELNGVRSHVYAYGMRNPNGMDFRGKELYTAENGPLTDDEFNRIEKGAN
                     YGWPNVAGYKDDQAYVYSDWAKAKGGCQKLTFTPNPGEAPVQVPTTRERDFTKAMEAPV
                     STYGTTVESGHDFGVTTVCTDPDSAYVCWPTMAPGALKVAGDEFLVTSLKNGTVYRLTK
                     DGKSFKQLHRSVNRYRDVALSPDGKTLYIATDSGGLVHGPDGAPTGKLANPGAILAVPY
                     GK*"
     CDS             7461..7600
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540779"
                     /pseudo=False
                     /translation="MIQHEERDDRSVERPDEATDQTAWHRPTYQIVEASMEMSAYFLSD
                     R*"
     CDS             7613..8424
                     /protein_domains="PF12706"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540780"
                     /pseudo=False
                     /translation="VRLHVLGTAAGGGVPQWNCACPGCCGARAVPSWRRLHASIAVEVE
                     PGRVYVVNATPDIGEQIERCGWLRPDGRRTPLAGVILTDAELDHTLGLARLREADELEI
                     MATDAVRKAVSEGLRLEETLAPYVRLRWRDVDGASLVPVSGKRPRYAREFPAWDGEWVS
                     ALSIGGLVYAPAMGVWPAGFGEGADVVFADGTFWDEDEPRRCGFSEKTGTEMGHLPVLA
                     TRDRLAALPARCFYTHLNNTNPLVDPDAPQYAELRGVEVASEGMFVEW*"
     CDS             8419..9134
                     /protein_domains="PF03070"
                     /protein_domains="TIGR02111"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540781"
                     /pseudo=False
                     /translation="MVIGLDAVSAGSAVGAAAFERELRAVPERHYHHRHPFNLRMHQGE
                     LTPGELRTWILNRFHYQRHIPVKDALILAKLDDPALRRMWVRRITDHDGTGDDEGGIER
                     WLRLGEAAGLDRADLLAGDRVLPGVRLAVDGYVNLCRNAGPLEAVAASLTELFAPDLMA
                     TRIAAFEKHYTWIRPEGLAYFASRVSQGRRDSGEALALVLGWARTRADQEAAVAALSYK
                     CEVLWTLLDAVDRASA*"
     CDS             9132..9370
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540782"
                     /pseudo=False
                     /translation="MSTAWRPALSPYARVRDCPVRKRTLLIVPERIVVLSTEAAAVVEL
                     CDGTRTVPEISAELGDGDGIAEFLDDVKERGWLR*"
     CDS             9359..10491
                     /protein_domains="PF04055"
                     /protein_domains="PF13186"
                     /protein_domains="TIGR02109"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540783"
                     /pseudo=False
                     /translation="MAALNPPSVNPPSVNPPWAMLAELTHGCPLRCPYCSNPTELVRPA
                     DELTTGDWLRVFDEAARLGVAHAHLSGGEPLLRRDLTELVAGAADAGIYAQLVTSGLGL
                     TSERLDELTAAGLPSVQLSVQGADAASSELIAGRRSFTAKARAAALIRDAGLPLGLNVV
                     LHRHNLDRLDEIIRLGVDWGAVRIELANTQFYGWGLRNRAALMPSREQLARAQRVVEEW
                     RGRTETELIWVVPDYFDGVAKPCMGGWGAISLTVAPDGRVLPCPAAYDLPLEAPNVREN
                     SLSWIWRESPAFNAYRGSDWLPDPCRSCPRKEADFGGCRCQAFALTGDAGRTDPACSLS
                     PDHGVIAELSGVRSGELVYRGYAAGNRQRAHGPTRVR*"
     CDS             10552..11174
                     /protein_domains="PF00440"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540784"
                     /pseudo=False
                     /translation="MTRGRPERKQRANGVESRRRILDAAVEIAGERGYEGTSIAAVSAQ
                     CGLPTSSIYWHFKDKDDLIAAVIERSFETWLTAVELPGEDAGTPLERVTTMAANVARSL
                     LDAPDFVRLGLMLALERRQVEPRGRGVYLDVRKAARQRITEVLRALFPEVDERAVDVLV
                     TYTVAGTDGLFVQQEIDGGIDLVGMFELHARTVYSMAEGMPTGG*"
     CDS             complement(11290..11930)
                     /protein_domains="PF18085"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540785"
                     /pseudo=False
                     /translation="MSIIHRTWLKPTKLEFLTPWLPTRAWYQGGTATPQLAKAGGFRLD
                     DPEGEVGIEFFVATDAEGPHAYLVPLTYRSAPLPGADHALITTLEHGVLGQRWVYDGVH
                     DPVLTGALAAFFEGRIPAQAQSTSDALDEEVTHAYAGGAPLLAGEVTVTETAEGTTLTT
                     PDGPAVRFDRLLTAVADTPPADALGHVTGAWTDVEGNRVRGVFAVVEARA*"
     CDS             12036..12910
                     /protein_domains="PF13354"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540786"
                     /pseudo=False
                     /translation="MARTNILGRRTLLALGAGAALTAAVAPSAHAATRDVFAGLEQEYA
                     ARLGVFAHDTATGRTLTHRADERFPMCSVFKAPAAAAVLREGVDLTRRIHYTQQELTDS
                     GYAPVTEKHLDTGMTVEELCAAAVSHSDNAAANFLLRELGGPTAITRFARSLGDSVTRL
                     DRWEPDLNSAEPWRKTDTTTPHAIARTYAKFLLGDVLPPADRTRLTSWMVANSTNVTRF
                     RAGLPADWILADKTGGGSSYGVANDVGVVWPPGRAPLVIAVLTTTYAAEGPSKNELVAR
                     AAELVAAELT*"
     CDS             13093..14609
                     /protein_domains="PF06964"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540787"
                     /pseudo=False
                     /translation="VPNATAVVNLDIEGPTISRHLYGHFAEHLGRCVYGGFWVGEDSDI
                     PNEGGIRLDVVEALRALNIPNLRWPGGCFADEYHWRDGIGPREERPRMVNTHWGNVEEN
                     NHFGTHEFMALCELLGAEPYISGNVGSGTVREMSEWVEYLTRDGDSPMVRLRKDNGREE
                     PWKVKYWGIGNETWGCGGNMRAEYSADLARQYATYCRDHGDNKLYRIASGASDADYKWT
                     ETLMQQISCFGCDATPRNFFQGVSVHYYTLAGPWEAKGSATAFDTDTYYRTMLAARRID
                     DILTGHSTVMDIYDRGRTVGLVLDEWGTWWDVEPGTNPGFLFQQNTMRDALVASTHFDI
                     FHKHAARLHMANIAQTVNVLQAMILTDGDRLVLTPTYHVFEMNKDHQDATSLAVHLKAD
                     EARRTVAGTELTTVSVSASVKNGQVLVSLSNLDAEEPAEVTLDLRGGTLGAPVARLLTA
                     GRIEDHNTPEQRDTVAPRPFDGVKTTDGGLTLTLPPHSFLTLQAPLN*"
     CDS             14614..15635
                     /protein_domains="PF13377"
                     /protein_domains="PF00356"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540788"
                     /pseudo=False
                     /translation="VATIQDVAKAAGVSAMTVSNVINGHPNVRRETRDRVLAAMARLDY
                     RVNVAARNLRKGRTGTIGLAVPEVDSPYYSRLAAGVIAAAGRHGLRVGIEQTGATRESE
                     LDALSLSRNRLYDGLLLSAVGLAQTDAERLTVEHPVVVLGDRIVGGPVDHVGMPNLEAS
                     RAAVTHLVERGCRRIALVCGETAEIDTSSLRHAGYRQALTDAGVPYDPGLVRQVGRFGL
                     AEGARCARDMVAGGLDFDGVFCVTDTLAMGVLRGLADSGVQVPGQVKVIGFDDIAESAY
                     LVPSLSSVDPDHDGMAERAVALLLTRIDQHEPPPRYEEFVSGFTLVIRESTGGPQGETR
                     *"
     CDS             15633..16555
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1540789"
                     /pseudo=False
                     /translation="MNPAPLFRDPVHDGAADPTAIWNRETEEWWLVYTNRRTTAPGPGA
                     AWVHGTDLGVAVSADAGRTWTYRGTLPNLDAEWGRNTFWAPEIIWHDGRYHLYVSYIRG
                     VPDSWAAPASIRHYTSPDLLTWTHHGPLDLDSERVIDACVHPLPDGGWRMWFKDETRGS
                     ATCAADSPDLYEWKPTGVVLDHRPHEGPNVFTLGGAHWMLVDEWRGQGVFRSDDLTTWE
                     YQGLVLDAPGHRVDDGNIAHHADVVVQDDTAYVFYFTHPGRPPGITDDDGTHRTRRSSL
                     QVATATVVDGVLHCDRSPVELNLRPI*"
ORIGIN
        1 ctatgcacca gcacgacggc tcaccacccg gtacaccgcg taaagcccca cggacagcgc
       61 gacgttgacg accgccacca cgcacgcgcc cgcgtagtcc gactccagga tcgccttgct
      121 gtagatcagc agcggcaggg tcgtcacgcc cttcgccccg gtgaacagca cgatcccgaa
      181 ctcgttgagg cacagcacca ggacgaggct cccgccggcc gcgagcgcgg gcagcgcctc
      241 gggcaggatc acccgccgca cgatcctcgg cgcccgcgcg ccgagactcg acgccgcctc
      301 gatctgcgcg gtgtcgagct gcgagaacgc cgcgagcagg ggccgcatca cgaacggcgt
      361 gaagtacgtg acctccgcga gcagcacacc ccagggcgtg gtcaggaact ggaacgagcc
      421 gacgatgccg gtcgtgccgt agatgaacag cagggcgagc gtgatcagga acgacgggaa
      481 ggacaggaac acgtccacga accgcgcgac cgccctcgcc ccggggaacg ggacgaacgc
      541 gatgaccagc gccaggaaga accccagcac cagacacccg gcggtggagg cgagcgccag
      601 ccacacggtc gtccacagcg cctgccggaa cgcctcggag gcgaaaacgt ccgtgtacgg
      661 ctggagcgac gtgccgcccg agtcgggctg gaaggactgc tggacgacca gggccagcgg
      721 atagaggaag aagacggcga ggagggcgac cggaggcagg gtccacagca ggcgtctagt
      781 catggagcag caccgcgtcc tcgggggaga agtgcagggt gacgcgcgcg ccgtggaccg
      841 gcgggtcccg cagctcgcgt acgtcggcca tgacggtgtg cccggcgacc tcgacgtaca
      901 gccggtgcgt ggcgccgcgc cactggatct cccgtacggg gccggtgagt tggttcggcc
      961 cttcgcccag cccgacgaga tgcggtcgga cacacagcgt cgccggaccg gtcacgtcct
     1021 tcgcgtcgac cttcatccgc gtccccgcga actccgcgac cccgtccgtc acttgcaccg
     1081 gcagcaggtt cgccccgccc acgaacgacg ccgtgaactc gtcccccggc gcccggtaca
     1141 gctcccgggg cgtcccgcat gcctggaggc gggcccggtc gagcaccgcg atccggtccg
     1201 ccagcgtcag cgcctcgaca tggtcgtgcg tgacgtacag gatcgtcatg tccggcaact
     1261 cccggtgcag tcgggcgagt tcggtgagca tctcggaccg cagccgggcg tccagcgccg
     1321 acagcggctc gtccaggagc agcacctcgg gccggatcgc caacgcccgc gcgatggcga
     1381 cgcgttgctg ctggccaccg gacaactccc ggggacggcg ccgcgcgtac gcccccatcc
     1441 cggtcaactc cagcgcctca ccgacccgtt gccggatctc gcccttgttg acgcggcgcg
     1501 ccttcagccc gaacgccacg ttgtcctcga cccgcatatg cgggaacagc gcgtactgct
     1561 ggacgaccat cccgatgccc cgccggtacg gcggtacgtc ggtcacgtcc cgttcgccga
     1621 ggaacacccg ccccgccgac ggccgcacga acccggcgac ggcccgcagc gcggtcgtct
     1681 tcccggaccc ggacggtccg agcagcgcta tcacctcacc cggctcgacg gtcaggtcga
     1741 gcgcgtcgag gacggtgttc ccgtcgtagg cgacgctcac ggagtcgaag cggatcacgt
     1801 cagtactccg ggcaactcgg cgacggagcc cagcacatga ccggccccgg ccgcccgcag
     1861 cgcctccgcg tcgtgcgccc cggtgaggac ccccgcgacc accccggccc cggcgcgcac
     1921 cccgctgagc acgtcgtacg aggtgtcccc gacgaccgcg acctgccgga cgccctcggc
     1981 ggccttcgtc cgcacgaacg cctccaggac catgtcgggg tacggccgcc cgcgcccgcc
     2041 cgcgtccgcc gggcacaggg tgagcgccac gaggtcgcgc cagccgagcg cgtcgaggat
     2101 cgcgtcctgg gtgacgcggg cgaaaccggt ggtcaggacg accgtccggc cctcggcggc
     2161 gagctgctcg atggcctcgc gggcgccggg gaccggggcg atcaggccgt cggcgacgag
     2221 gtcgccgtac gcctgctcga aggcggtgtt ggcgcgctgg gcggtttcct cggtctggag
     2281 gaggtggcgg aagacggaga tcttcgactc gcccatcgtg gtgcggacgt aggcgagccg
     2341 gtcgggggtg gggtcgaggc ccagcgagcc cagggccgtc gtgaaggcgc gttcgaccag
     2401 gccgccgtcg gcgacggtcg taccggccat gtcgaggacg acgaggcgga tgtcgtgcgg
     2461 catgtcggtg gtcatggggt tcaccagccc aactggtctg cggtggtctc ggcgatggcg
     2521 ggtgcgcagg tcatgccgcg tccgccgggg cccgtgacca gccagacgcc gtcgcggacc
     2581 tgctggcggt gcacgacacg gctcgtgtcg aggcactgcg cgtacacgcc cgcccagcgg
     2641 cggcggatcg cggggagcgg gcggccgagg agggactcga cgacgccggt caggtgctcg
     2701 taggggtcct cgacggtgtc gaaggagaag gggtgctcgt actcgtgggt gtcgccgacg
     2761 gtcaggccgc cgtccgcgcg ctggaccatg aggagctgca tccggtgctc ggccgccgta
     2821 tcgggctgcg gctggcggga gttgagggcg tccagggcgg gggaggcgta cgccgggtag
     2881 tagcggaagc tgtccgcgtc cgcgaccgac gtcgtcaggg gttcgccgag cggcgcggtc
     2941 tgcatcatct gcaaccggac gcggcgcacg gggagttcgg gcccggccag ctcgcgcacc
     3001 aggccaccca gccaggcgcc ggtgcacagg acgacggcgt cgcccgtgtg cacgtcgccg
     3061 tggtcgtcgc gcacggcgtg ctcgccgatc acctcacgga cctcgcggcc cgggaggaac
     3121 gtgtagcgcg ggttcctcaa cagctcggcg cgcagggcgc gttgggcggt ccggggttcg
     3181 acggccgcgt cccgtgcgca gtacagggcc gcgccgaact ccccgcgcag cgccgggttc
     3241 agcgcccgtg cctcgcccgg cgtcagcagc tcgtaccccc gcacgtccgc gtcgccccgc
     3301 gccgccgcgt actcggcgac ggcgtgttcg aggccgccgc gtacgacggt cagggacccg
     3361 ttggcgcgga agccgagcgc cgggacgcgc tcgccgatcc cctcccacag ctccctcgcg
     3421 cgcagcgcgg ccgacagctc ctcgccgtcc gcgcgtccgc tcacccagac gagcccgaag
     3481 ttgcgcagcg acgcgccccg ggcctccgcc tcgcgctcga tctgtacgac ctcgtggccg
     3541 cgttccagtg cttgccaggc gtgcagggtg cccaccacgc cggctccgac gactatcact
     3601 ctcacgaccg tcacgctcct cgccgtgcgg gaaccggaag ggtccggctg acgacgtgag
     3661 catgaaccgg ccatcacatt tgggctagac ccgttatctg ttcgttactt tagtgcggtc
     3721 ggataatcgg tctttatcgg tttttcagtt cttgagatgc gccgagaacg agaaccggtc
     3781 cccccggtac aggctccgca cccgctccag cggactcccc tccgcgtccc gtgacacccg
     3841 gtggatcagc agcatcggca gcgccggggg agtcccgatc agcagcgcct cgcgcggcgt
     3901 cgccagaacc gtctcgatgc gctcgtcggc ctgaccgagc cggatgccct ggccgcccat
     3961 gtaggcgtag aacgaggagt ccgggtcgaa ctcggcgtcc aggcgcggga gtcgggcgac
     4021 ggagacgtac gtgctctcca ggcccacccg ctcgtcgtcg gccagcagca cccgctccag
     4081 gtgccacacc ggctcgccgc gcgtcagccc cgtctcctcg gccagcggcg ccgggcacgg
     4141 gaaccggtcg agggcgacga gactgcggcc cggcgtccgg ccctgcctgc gcacgccctc
     4201 cgtatagctg gccagcgcga gcggctgctc cagcttcggc cccgcgacga cggtcccccg
     4261 gccctgccgg cgcagcttgc cctccagcag caactcccgc agcgcctgcc gcaccgtctc
     4321 gcgcgccacg tcgtaccgct cggagagatc ccgctcggtg gggatgacag caccctcgcc
     4381 gaggtcgctc acgaggtcgt ctatacgggc cttgaccgcg tagtacttgg gcacacggcc
     4441 gtgctcgggg acaccggcgc ggacgggagc gccggggtgc tgatcattcg ggtagtccac
     4501 gggtggaccg tacacggacc ccgccgcgac cccgtcgtac gacggccgaa ccgctccttg
     4561 ctgcatcatg cacacctgcg tagcgtcgac agcgccccac ggaggtgcgc gatgaccgag
     4621 ctccgactcc ccttacctgc cgaaggcccc ctggaaccgc ccgccgcctg ggccgacctg
     4681 cgccgcgagt gcccggtcgc gtccgtccgg ctccccagcg gcgacgaggc gacgctcctg
     4741 acccgctacg acgacatacg caccctgctc tccgaccccc gcttcgcccg cccggccgcc
     4801 gaggacggcg ccgcgcggct cgcccccgag ggagcgggcg gccccgtcgt cgacggagag
     4861 ttgcaggacg tcatacccga ccgcggcgaa ggccatcagc ggtggcggcg ccaggtcggc
     4921 aagtacttca ccgccaaacg catgaccgcc ctacgccccg cgatcaccga gcgggccgac
     4981 cggctcgtcg acagcatggt cgagcagcgc caacccgccg acctgaaggg cgcgttcggg
     5041 ttcccgctgc ccgtgtacgt gatctgtacg atcctcgggg tccccgccga ggacagcgac
     5101 cgcttctcgc actggtccga cgccttcctc aacgtcagcc ggtggacgaa ggaggagagc
     5161 gcggcggcgt acgaggagtt cgacgcgtac atgtcccggc acatcacgca cgtccgcgag
     5221 caccccggcg acgacctgat cagcatgctc atcgccgacc aaccggacgt gaccgacacc
     5281 tggttgctgc gcaccggcat gggactgctc gtcgccggac acgagacgac cgccaacgcc
     5341 atcggcaaga ccgtcgcgat gctgctggcc gaccgggaac tgtgggaact cctgctggcc
     5401 gagccggagt tggtgcgcac gaccgtcgac gaggcgctcc gcctggacgt caacctcggc
     5461 ttcgggctgc ggcgttacct caccgaggac gtcgaggtcg gcggctcggt gctgccgcgc
     5521 ggcgccaccg tcgtctgcgc cctgcccgcc gccaaccggg acgcggcggc cttcgaggac
     5581 ccggacctca tgctcctgtc ccgcagcccc aacccgcacc tcgcgttcgg cgcgggcccg
     5641 cacgcctgcc tgggacagag cctcgccagg accgagctcc aggtcgccct ggaggtgttg
     5701 ctcaggcggc tgcccgcgct gcggctcgcc gtgccggtcg gtgaactgcg gcgcctggag
     5761 ggcctgttgg tgggcgggct gagcgaagtg ccggtcacgt ggtgagggtc gccgtcgacc
     5821 gttcgctgtg ctgcggggcc gggaactgcg tcctcgtcgc gcccggagtg ttcgaccagg
     5881 acgaggacga cggggtcgtg gtgctgctca cggagacgcc cgcttcgtcg gacgaggccg
     5941 cgacgcggga ggcggcggcg atgtgccccg cctccgcgat cacattgcgt gacgatatgt
     6001 accgggatgc gtgatatgtg agccgacctt agggtgaggc cgcgaggggg cccttccgaa
     6061 aggtcaacga tgagaaagct tccgtcggca ctggctctgg ccgccgtcgc ggcactcgtc
     6121 tgctcctgcg gcagcgggtc cgcgacaggg acggtccagc gcgccgccgc cgtgaacctg
     6181 gacgccaagg ccggcttcac ggtcgtcacg accgggctcg gggacccgta cgagatgatc
     6241 cagggccccg acgggtacct gtggctcacc gagaagtccg gcctcaaggt cacccgcgtc
     6301 gacccgaaaa ccggcgccaa gaccaccgcc ctggacctgg ccaagaaggc cgtccgcgcc
     6361 aagggcggca aggacggagt cctcggcctc gcgctgcacc ccgacttcgg gaagaagaag
     6421 gacaaggact acgtctacct gtcctacagc tccatggacg gcgtgaaaga ggccaccagg
     6481 atcgtcaggt acacggcgaa gaacgggaag ctctccggcg agtacaccgt cctgagcggc
     6541 ctccccgccg gcgacgacca ccaggccgca cgcctgcgct acggtcccga cggcaagctc
     6601 tactactcga tcggcgacca gggcgcgaac tactacgccc actactgcgt cccgaaccag
     6661 gcccagaacc tgccgaccgc cgaccaggtg aagaagaagg actggtcggt gtaccccggc
     6721 aagatcctgc gcatgaaccc cgacggctcg atcccggacg acaaccccga gctgaacggc
     6781 gtccgcagcc acgtctacgc ctacggcatg cgcaacccca acggcatgga cttccgcggc
     6841 aaggagctgt acaccgccga gaacggcccc ctcaccgacg acgagttcaa ccgcatcgag
     6901 aagggcgcga actacggctg gccgaacgtc gccgggtaca aggacgacca ggcgtacgtc
     6961 tactcggact gggccaaggc caagggcggc tgccagaaac tcaccttcac gcccaacccc
     7021 ggcgaggccc ccgtgcaggt gccgacgacc cgggaacggg acttcacgaa ggccatggag
     7081 gcgccggtca gcacgtacgg cacgacggtc gagtccggac acgacttcgg cgtgaccacg
     7141 gtgtgcaccg accccgacag cgcgtacgtg tgctggccga ccatggcacc cggcgccctc
     7201 aaagtggctg gtgacgaatt cctcgtcacc tccctcaaga acgggaccgt ctaccggctc
     7261 acgaaggacg gcaagtcctt caagcagctc caccggagcg tcaaccgcta ccgcgacgtc
     7321 gcgctgagcc ccgacggcaa gaccctctac atcgccaccg acagcggcgg actcgtccac
     7381 ggccccgacg gcgcccccac gggcaagctc gccaatcccg gcgcgatcct cgccgtcccc
     7441 tatggaaagt gagacccgga tgatccagca cgaggaacgg gacgacaggt ctgtggagcg
     7501 tcccgacgag gcgacggacc agaccgcctg gcaccggccc acttatcaga tcgtcgaggc
     7561 gtcgatggag atgtcggcgt acttcctcag cgaccggtag ggggccgcgc cgtgcgcctg
     7621 cacgtactcg gtacggcggc cggtggcggc gtcccccagt ggaactgcgc gtgtcccggg
     7681 tgctgcgggg cgcgcgcggt gccgtcctgg cggaggctgc acgcgtcgat cgccgtcgag
     7741 gtcgagcccg gccgggtcta tgtggtcaac gcgacgcccg acatcggcga acagatcgag
     7801 cggtgcggct ggttgcgtcc tgacgggcgg cgtactcctc tcgcgggggt gatcctcacc
     7861 gacgccgaac tcgatcacac gctggggctc gcgcggcttc gggaggccga tgagctggag
     7921 atcatggcga cggacgcggt gcggaaggcg gtgagtgagg ggctgcggct ggaggagacc
     7981 ctcgcgcctt atgtgcggtt gcggtggcgg gacgtggacg gtgcttcgtt ggtgccggtg
     8041 tccggtaaac ggccgaggta cgcgcgggag ttcccggcat gggacgggga atgggtcagc
     8101 gcgctgagca tcggggggct ggtgtacgcg ccggccatgg gggtgtggcc cgccgggttc
     8161 ggggaagggg cggacgtcgt gttcgccgac gggacgttct gggacgagga cgagccccgc
     8221 cgctgcgggt tctccgagaa gacggggacc gagatggggc acctgccggt tctcgcgacg
     8281 cgggatcggc tggccgccct gcccgcgcgg tgcttctaca cacacctcaa caacaccaac
     8341 cccctcgtgg accctgacgc gccgcagtac gcggagttgc ggggcgtcga ggtggcttcg
     8401 gaagggatgt tcgtcgaatg gtgatcggtc tggatgccgt gtctgcgggg agcgcggtcg
     8461 gggccgctgc cttcgagcgt gaactgaggg cggttcccga acgccactac caccaccggc
     8521 atcccttcaa cctccgtatg caccaaggag agttgacgcc cggcgaactc cgcacctgga
     8581 tcctcaaccg cttccactac cagcggcaca tccccgtcaa ggatgccctg atcctcgcca
     8641 agctcgacga ccccgccctg cgccgcatgt gggtgcgccg catcaccgac cacgacggca
     8701 ccggcgacga cgagggcggc atcgaacgct ggctgcgcct cggcgaggcc gccggactcg
     8761 accgggccga cctcctcgcc ggtgaccggg tgctgccggg cgtacggctc gccgtcgacg
     8821 ggtacgtcaa cctctgccgc aacgcaggcc cgctcgaagc cgtcgccgcg tccctcaccg
     8881 aactgttcgc gccggatctg atggcgaccc ggatcgcggc gttcgagaag cactacacgt
     8941 ggatcaggcc cgaggggctc gcgtacttcg cctcccgtgt gtcccagggg cgtcgggaca
     9001 gtggcgaggc gcttgccctt gtgctggggt gggctcgcac tcgcgctgat caggaggctg
     9061 ctgttgccgc gctctcctac aagtgcgagg tgctgtggac tctgctggac gccgtcgacc
     9121 gggcgtccgc atgagtacgg cttggcggcc ggccctcagc ccgtacgcgc gcgtgcgtga
     9181 ctgtccggta cggaaacgga cgctgctgat cgttcctgaa cggatcgttg tcctcagtac
     9241 cgaggctgcc gcagtggtcg agctgtgcga cgggacccgg accgttcctg agatcagcgc
     9301 cgaactcggg gacggggacg ggatcgccga gttcctcgac gatgtgaagg agcgcggatg
     9361 gctgcgctga acccgccctc ggtgaatccg ccctcggtga acccgccgtg ggcgatgctc
     9421 gcggagctca cccacggctg ccccctgcgc tgcccctact gctccaaccc caccgaactc
     9481 gtgcgccccg ccgacgagtt gaccaccggg gactggctgc gcgtgttcga cgaggccgcc
     9541 cgcctcggcg tggcccacgc ccacctctcc ggcggcgaac ccctgctgcg gcgcgacctg
     9601 accgagctgg tcgccggtgc cgcagacgcc gggatctacg cccaactcgt caccagcgga
     9661 ctcgggttga cgtccgagcg gctcgacgag ctgacggcgg ccggtctccc cagcgtccag
     9721 ctctccgtgc agggcgcgga cgccgcgagt tccgaactca tcgccgggcg ccggtcgttc
     9781 accgcgaaag cgagggccgc cgcgctgatc cgggacgccg gtctgccgct cggcctcaac
     9841 gtcgtcctgc accggcacaa cctcgaccgg ctcgacgaga tcatccgact cggcgtcgac
     9901 tggggagccg tacgcatcga actcgccaac acccagttct acggctgggg gctgcgcaac
     9961 cgggccgcgc tcatgccgag ccgggagcaa ctggcccgtg cgcaaagggt ggtcgaggag
    10021 tggcgggggc gtacggagac ggagttgatc tgggtcgtgc cggactactt cgacggggtg
    10081 gcgaaaccct gcatgggagg ctggggcgcg atctcgctga ccgtggcccc cgacgggcgg
    10141 gtgctgccct gtcccgccgc ctacgatctg ccgctcgaag cgcccaacgt ccgtgaaaac
    10201 tcgctgagtt ggatctggcg cgagtcgccc gcgttcaacg cctaccgggg gagcgactgg
    10261 ctgcccgacc cctgccggtc ctgcccacgg aaagaggccg acttcggggg atgccggtgc
    10321 caggcgttcg cgctcaccgg ggacgccggg cggacggacc cggcgtgttc gctgtcgccg
    10381 gaccacgggg tgatcgccga actgtcgggc gtacggagcg gggagttggt ctatcggggg
    10441 tacgcggccg gaaatcgtca gcgggcgcac gggccgacta gagtgcggtg atcgtcgacg
    10501 cgtaccccga aaagcgaggt gtacgcctct gagagacgga gaatcactga atgacccggg
    10561 ggagacccga gcgcaagcag cgtgccaacg gggtggagtc gcggcggcgc atcctcgacg
    10621 cggcagtcga gatcgcgggg gagcgggggt acgagggcac gtcgatcgcg gccgtcagcg
    10681 cccagtgcgg gctgcccacc agctcgatct actggcactt caaggacaag gacgacctga
    10741 tcgccgccgt tatcgagcgc agcttcgaga cctggctgac ggccgtcgaa ctgcccggcg
    10801 aggacgcggg gaccccgctg gaacgggtca cgaccatggc cgcgaacgtc gcccgctccc
    10861 tgctcgacgc gcccgacttc gtgcggctcg ggctgatgct cgcgctggag cggcggcagg
    10921 tcgaaccccg ggggcggggc gtctacctgg acgtccggaa ggcggcgcgg cagcggatca
    10981 ccgaggtcct ccgggcactg ttcccggagg tggacgagag ggctgtggac gtcctcgtca
    11041 cctacacggt cgccgggacc gacgggctgt tcgtccagca ggagatagac gggggcatcg
    11101 atctcgtcgg gatgttcgag ctgcacgcgc ggacggtgta ctccatggcg gaggggatgc
    11161 cgaccggggg gtgaggccgg tcggcgaact gcggtgcgtc tcaggtggtg tgcctctgcc
    11221 ggtgtgcgct gtgtttcggc cggaattgct gctgctgacg tgtgctgcgc cgcccgccga
    11281 gggccgtgtc aggcccgcgc ttcgaccacc gcgaacactc cgcgcacccg gttgccctcc
    11341 acgtcggtcc acgcgccggt cacatggccg agcgcgtccg ccggaggggt gtccgccacg
    11401 gcggtcagga gccggtcgaa gcggacggcg gggccgtccg gcgtcgtgag ggtcgtgccc
    11461 tcggccgttt cggtcaccgt cacctcgccg gccagcagcg gggccccgcc cgcgtacgcg
    11521 tgggtgacct cctcgtccag ggcgtcgctc gtgctctggg cctgggccgg gatgcgcccc
    11581 tcgaagaacg ctgccagggc gccggtcagc actgggtcgt ggacgccgtc gtacacccag
    11641 cgctgtccga ggacgccgtg ctccagggtg gtgatcagcg cgtggtccgc gccggggagc
    11701 ggggcggaac ggtaggtgag ggggaccagg taggcgtgcg ggccctcggc gtcggtggcg
    11761 acgaagaact cgatgccgac ctcgccctcg gggtcgtcga gacggaagcc cccggccttg
    11821 gcgagctgcg gggtggccgt accgccctgg taccacgcgc gcgtggggag ccacggggtg
    11881 aggaattcga gcttggtcgg cttgagccag gtgcgatgaa tgatcgacat gttcagggat
    11941 tctccatcag ggtccgcgat gatcgaaact gtttcttccg gggtcgcgtc ctgatcgact
    12001 gagccaagat caacgaccgt gaggacggac gaccatggca cgaacgaaca ttctgggacg
    12061 ccgcaccctc ctcgccctgg gcgccggagc ggctctgacg gcggcggtgg cgccctcggc
    12121 ccacgccgct accagggacg tcttcgccgg actggagcag gagtacgccg cccggctggg
    12181 cgtcttcgcc cacgacacgg cgaccgggag gacgctgacg caccgtgcgg acgaacggtt
    12241 cccgatgtgc tcggtgttca aggcgccggc tgcggcggcc gtcctgcgcg agggcgtgga
    12301 cctgacgcgg cgcatccact acacgcagca ggagttgacg gactcgggat acgcgccggt
    12361 caccgagaag cacctcgaca ccggcatgac cgtcgaggaa ctctgcgccg ccgccgtctc
    12421 ccacagcgac aacgccgccg ccaacttcct cctgcgcgaa ctcggcggcc ccaccgcgat
    12481 cacccgcttc gcccgctccc tgggcgactc cgtgacccgc ctcgaccgct gggagcccga
    12541 cctcaactcc gccgaaccct ggcggaagac ggacacgacg acaccccacg cgatcgcccg
    12601 tacctacgcg aagttcctcc tgggcgacgt cctcccgccc gccgaccgca cccgcctcac
    12661 gtcctggatg gtcgccaact ccaccaacgt cacccgcttc cgcgccggtc tccccgccga
    12721 ctggatcctc gccgacaaga cgggcggcgg gagttcgtac ggcgtcgcca acgacgtcgg
    12781 cgtggtgtgg ccgcccggcc gggcgccgct ggtgatcgcc gtgctgacga cgacgtacgc
    12841 ggccgagggg ccctcgaaga acgagctggt cgcgcgggcg gcggagctgg tggcggccga
    12901 gctgacctga gcggatcgcg gaacggccgg cggggagcgc ttcgccggcc gttcgcggga
    12961 gcgaaagttt ccgtgactcc cgtggggccg ggcgaccttg acgctcccgg tggcgcgatg
    13021 gcagcttttt atcgctacaa acgatcacct cgacgtcgta caagtcaccg catatctccc
    13081 ggggagcagc tgtgcccaac gccaccgcgg tcgtcaacct ggacatcgaa gggccgacga
    13141 tcagccggca cctctacggt cacttcgccg agcatctcgg gcgctgcgtc tacggcgggt
    13201 tctgggtcgg ggaggactcc gacataccca acgagggcgg gatcaggctc gacgtcgtcg
    13261 aggcgctgcg cgcgctgaac attcccaacc tgcgctggcc cggcgggtgt ttcgcggacg
    13321 agtaccactg gcgggacggg atcgggccgc gcgaggagcg gccccggatg gtcaacacgc
    13381 actgggggaa cgtcgaggag aacaaccact tcggcaccca cgagttcatg gcgctgtgcg
    13441 aactcctcgg tgcggaaccg tacatcagcg ggaacgtcgg ctccgggacc gtccgggaga
    13501 tgagcgagtg ggtcgagtac ctgacccgcg acggcgacag cccgatggtg cggctgcgca
    13561 aggacaacgg ccgcgaggag ccgtggaagg tcaagtactg ggggatcggc aacgagacct
    13621 ggggctgcgg cggcaacatg cgcgccgagt actccgccga cctggcccgc cagtacgcca
    13681 cgtactgccg cgaccacggc gacaacaagc tgtaccggat cgcctccggc gcctcggacg
    13741 ccgactacaa gtggaccgag acgctgatgc agcagatcag ctgtttcgga tgcgacgcga
    13801 cgcccaggaa cttcttccag ggcgtgtccg ttcactacta cacactggcc ggaccgtggg
    13861 aggcgaaagg cagcgcgacc gcattcgaca ccgacaccta ctaccgcacg atgctcgcgg
    13921 cccgccgcat cgacgacatc ctcaccggac actccaccgt gatggacatc tacgaccgtg
    13981 gccgcacggt cggcctggtc ctcgacgaat ggggcacctg gtgggacgtc gagccgggca
    14041 ccaacccggg cttcctcttc cagcagaaca ccatgcgcga cgcgctcgtt gccagcacgc
    14101 actttgacat cttccacaag cacgcggccc gcctgcacat ggcgaacatc gcccagacgg
    14161 tcaacgtcct ccaggcgatg atcctcaccg acggcgaccg actggtcctc actccgacgt
    14221 accacgtgtt cgagatgaac aaggaccacc aggacgccac ctcactcgca gtccacctca
    14281 aggccgacga ggcccgacgc accgtcgccg ggacggaact cacgaccgtc tccgtctccg
    14341 ccagcgtcaa gaacggccag gtcctcgtct ccctctccaa cctcgacgcc gaagaaccgg
    14401 cggaggtcac cctcgatctg cggggaggta ccctcggcgc cccggtcgcc cggctcctga
    14461 cggccggccg gatcgaggac cacaacacgc ccgagcagcg ggacacggtc gcgccgcgcc
    14521 ccttcgacgg ggtgaagacg acggacggcg gcctgaccct caccctgccg ccgcactcct
    14581 tcctcacgct ccaggccccg ctgaactgac ccgtggcgac catccaggac gtggcgaagg
    14641 cggccggggt gtccgcgatg accgtctcca acgtcatcaa cggccacccc aacgtacggc
    14701 gggagacccg ggacagggtc ctcgcggcga tggcccggct cgactaccgg gtcaacgtcg
    14761 cggcccgcaa cctccgcaag ggccgcaccg gcacgatcgg cctcgccgtg cccgaggtcg
    14821 acagcccgta ctacagccgc ctcgccgccg gcgtcatcgc cgccgccgga cgccacggcc
    14881 tgcgcgtcgg catcgaacag accggcgcca cgcgggagag cgaactcgac gccctctccc
    14941 tctcccgcaa ccgcctctac gacggcctcc tgctcagcgc cgtcggcctg gcgcagaccg
    15001 acgccgagcg cctcaccgtc gagcaccccg tggtcgtgct cggcgaccgc atcgtcggcg
    15061 gacccgtgga ccacgtcggc atgccgaacc tggaggcgtc ccgggcggcc gtcacccacc
    15121 tcgtcgagcg gggctgccgg cggatagcgc tggtctgcgg ggagacggcc gagatcgaca
    15181 cgtccagcct gcgccacgcc gggtaccggc aggccctcac cgacgcgggg gtgccgtacg
    15241 accccgggct ggtccgccag gtcggccggt tcgggctcgc cgagggcgcc cggtgcgcgc
    15301 gggacatggt cgccgggggc ctggacttcg acggcgtgtt ctgcgtgacc gacaccctcg
    15361 ccatgggcgt cctgcgcggc ctcgccgaca gcggcgtaca ggtgcccggc caggtcaagg
    15421 tcatcgggtt cgacgacatc gccgagagcg cgtacctcgt cccgtccctc tccagcgtcg
    15481 accccgacca cgacggcatg gccgaacgcg ccgtcgccct cctgctcacc cgcatcgacc
    15541 agcacgaacc gccgccccgg tacgaggagt tcgtgagcgg tttcacgctc gtgatccgcg
    15601 agtcgaccgg cggcccgcaa ggagagaccc gatgaacccc gcgcccctct tccgcgaccc
    15661 cgtccacgac ggcgccgccg acccgacggc gatctggaac cgcgagaccg aggaatggtg
    15721 gctggtctac accaaccgcc gcaccaccgc cccgggcccc ggcgccgcct gggtccacgg
    15781 caccgacctc ggcgtcgccg tctccgccga cgccggccgc acctggacct accggggcac
    15841 cctccccaac ctggacgccg agtggggccg caacaccttc tgggcaccgg agatcatctg
    15901 gcacgacggc cgctaccacc tctacgtcag ctacatccgg ggcgtccccg actcctgggc
    15961 cgcccccgcg agcatccgcc actacaccag ccccgacctc ctcacctgga cccaccacgg
    16021 ccccctcgac ctcgactccg agcgcgtcat cgacgcctgc gtccaccccc tgcccgacgg
    16081 cggttggcgc atgtggttca aggacgagac caggggctcg gccacctgcg ccgccgacag
    16141 ccccgacctg tacgagtgga agccgaccgg cgtcgtcctc gaccaccgcc cccacgaagg
    16201 gcccaacgtc ttcaccctcg gcggcgccca ctggatgctc gtcgacgaat ggcgcggcca
    16261 gggcgtcttc cgctccgacg acctcaccac ctgggagtac cagggcctcg tcctcgacgc
    16321 ccccggccac cgcgtcgacg acggcaacat agcccaccac gccgacgtcg tcgtccagga
    16381 cgacaccgcg tacgtcttct acttcacgca ccccggccgc ccgcccggca tcaccgacga
    16441 cgacggcacc caccgcaccc gccggtcctc cctccaggtc gccacggcca cggtcgtcga
    16501 cggcgtcctg cactgcgacc gctcgcccgt ggagctgaac ctcaggccga tctga
//
