LOCUS       reptomyces_RBGC_127627 15914 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_127627
VERSION     Streptomyces_RBGC_127627
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001279985.1
  ORGANISM  GCF_001279985.1
            .
FEATURES             Location/Qualifiers
     CDS             2..375
                     /protein_domains="PF13474"
                     /protein_domains="TIGR02246"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397239"
                     /pseudo=False
                     /translation="MSITADSEAVLRGVLDQWKAAIERHDPGQVAARFTEDAIFQGLHP
                     YSVGRPGVAAYYDSQPAGLSPAYRIRETRRLADDLVLGYVNVEFSIPDRPTVDVHLGVL
                     LKHTDGDWYISHYQVSRLDG*"
     CDS             complement(456..1291)
                     /protein_domains="PF11716"
                     /protein_domains="PF02036"
                     /protein_domains="TIGR03083"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397240"
                     /pseudo=False
                     /translation="VQPTVRQDMTGPLPEGLAEALRATAEEIAALLRDVPDTAIPVPGL
                     EWSVGEVAAHLAQANELMADLASGRERPYGDGTPQSLAAANARALDAFEERRAEPLAAM
                     IAERTEVFLKAVERAEDATSDSGTALVTPLGPMNRAVLASYLLTHMLGHGYDLARALRR
                     PHMIDRDRVELCMPFMLAVMPAVADKAATAGLTARYTVRLRDGSPFGVGLADGDVHVVA
                     GPMERADCTILIDPVAFLLIALGRRNPWRAIARGQVLTWGRKPWLGPRFPTLFTAP*"
     CDS             1768..2231
                     /protein_domains="PF03364"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397241"
                     /pseudo=False
                     /translation="MSMVKESIDVAVPVTTAYNQWTQFEEFPNFMEGVEEVRQVDERHN
                     HWTTKIGGVRREFDTEIVDQFPNERITWRTVGGHPEQRGMVSFQALDENHTRVALVMDV
                     DPSGAAERTADMTGMIDRRVKGDMRHFKEFVEDRGGESGEWHGRIRPGQM*"
     CDS             complement(2517..2734)
                     /protein_domains="PF09947"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397242"
                     /pseudo=False
                     /translation="MNCYECSTQSGATTTAEGVCQRCGAGICADHVRLRTQELQQQAGM
                     GSRSQPQPARRLLCPQCDKVEPSRPRP*"
     CDS             complement(2893..3596)
                     /protein_domains="PF07729"
                     /protein_domains="PF00392"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397243"
                     /pseudo=False
                     /translation="MSAVDKAFHGLRHMIATGRLGPGDRIPPEGDLCAELGVSRGSLRE
                     AVRMLAALGVIEPRHGSGTYVSQLRPEDVIGSLSLTLELLPLSGLLEVYEIRRVLEAHV
                     AAQAAARCTPEAVRTLFSLIEEMEATEDPAEASELDHRFHAEIARIGGNPTLATLLAVF
                     RARSRKYQVFTLPEGPRMRRKSDEDHHVLATAIADRDPVSAAGAAQAHVAQTERWLRAF
                     MPPVEEHDVAAE*"
     CDS             3616..3788
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MNGPPESPEASAHCSESSNVPDVSPRSHQMTFLVRPLSRPKNPCQ
                     DAESSYVSTQDV"
     CDS             3817..5069
                     /protein_domains="PF00266"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397244"
                     /pseudo=False
                     /translation="MWSAVSETEVTTAPRPLLLADGRPADRAWSLDPGMKHLNHGSFGA
                     VPLQAQERQELLRVEMERSPVVWFPALPQRIAATRVDLAAFLRVAADDLAVVPNASAGA
                     SVVFAALDRVRGGEIVVTDHGYGAVTMGAERLARRWGGRVRTAEVPLDANEEQAYEAVC
                     AELGDDTDLVVVDQITSATARRMPVERIGAEAHRRGIPMLVDGAHAPGLLAAPLAGATY
                     DFWVGNLHKWGCAPRGTAALIARGPLRDRLYPLIDSWGAADPYPDRFDQQGTIDATACL
                     AAPTALDFVERTWGWTAARDYMSELADYGAHVIGTAFAELTGRDSRVDVGLPVPGMRLV
                     RLPEGLGTGRVEADALRDRAAAELGVEAAFTSFGGTGYLRLSAHVYNTAADYEYFAEEC
                     VPVLGEWARTAREQHRAP*"
     CDS             5139..6439
                     /protein_domains="PF13416"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397245"
                     /pseudo=False
                     /translation="MRRRTAALALGTAAAMVLTGCSTMSPDASGTVTLNMVESLTNPTR
                     TDLLKDLIADFQQQNPKIKVNLISPPTEQADQKLQQMLQSGSGVDVLEVRDITVGPWSN
                     NGWLYDMKKDLDGWKGWPAMTENAVKAARNDEGKTYFVPYGFYGLSLFYRTDLIEKAGF
                     SEPPATWAELLEQASAVHDPSQRRYGYAFRGGSNANSNATAVIEAYVADQVDPANGYKL
                     KNGRTIFSAPEAQDALETYLKLFQRASPKSSVSWGYPEMVEAFSNGSTAFLLQDPEVIA
                     TVSESKSISEGQWGTAPLVAGPGGKTVQPLATAGWGVAQGGKHKPEAVKLVQFLSQGEA
                     STTFTKKNSLVPILKSATADPFYRTGPWASYVTMTEQPEKYLVVTQPRGVAWWTEWEQR
                     ADTDVQKLALGKTTPKELLASWDAYWTEKWRQEQ*"
     CDS             6443..7422
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397246"
                     /pseudo=False
                     /translation="MSVASTPTKTSTPGRGGATRAGGAPRGGRRKREFTTRRGALIAAF
                     MAPAAVFVAVFTYYPMIAGGQMAFRNWKLTDLTDTSWVGLKNFADVFADPAWGTVLGNT
                     AVWVVGSIVPQLVIGFALALWLRRRFRFRGLYQALIFFPWAISGFLIGILFRWMFNSEF
                     GVVNDLLQKAGLIDEPIAWLADPDTAMVAVLIANIWYGVTFFTIMILAALQSIPDELYE
                     AAALDGAGKARTLFRITIPYIRTTLVLTVLLRVIWIFNFPDLIFGMTGGGPNDETHIVT
                     TWMIQITQQGDYGRASALGLLVVGALLMFAVFFLLATREKKGVRS*"
     CDS             7420..8255
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397247"
                     /pseudo=False
                     /translation="VIGKETAAGRAGKFTFLGLWLAFTVFPLYWITATSFKAPGDIFRF
                     PIDYWPEHLSLENYSGLFATADFGTYLVNSLVVATVAGAVATVISMLSAYVLARFEFRT
                     KSALLMAALVTQMIPSFIALGPLYLLMTDLKLVDNHLGLILVYIAVCIPFCTVMLRGFF
                     ENIPDALEEAAMIDGLSRFGALFRVLLPVMRPGIVAAFIFNFVNCWNELFLSVTLMNSD
                     SNKTIPTALNGFISSFNIDWGSMSAAAVLTILPTMLLFAFASRHIVQGLTSGAVKG*"
     CDS             8338..9686
                     /protein_domains="PF07992"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397248"
                     /pseudo=False
                     /translation="MREILIVGGGYAGFYTAWGLEKRLRKGEARVTVVDPRPYMTYQPF
                     LPEVTAGSIEARHAAVSLRRHLHSTRLMAGSVIEISNADRTVTVRSANGAEQQLRYDIL
                     VVTAGAVTRTFPVPGLAQHAIGLKHVEEAVAIRDRLMTAFDQAASLPPGPERRKLLTVT
                     FVGGGFSGVEGFGELLSLATAMLKSYPELSMDDLSFHLVEARGRILPEVTDEPGSWVVR
                     SLERRGAHVHLNTQLLSVEDGHVVLSNGQEFDSALVVWTAGNAANPVVHNHTDLPVDQR
                     GLLVVRPDLRVGTDSEPVKDVWAAGDDAAVPDLAVPGAYTVPNAQHAVRQGKRLAKNIV
                     ADLRGGKTRNYRHSSLGVVATLGLGRGIFQYKRIVIKGLPAWLMHRGYHVLAVPTWERK
                     VRVLAVWLTAAVYGRDLVSLASVQHPRDAFVTSGDPERSGKSRQDDRAAA*"
     CDS             9958..10232
                     /protein_domains="PF02467"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397249"
                     /pseudo=False
                     /translation="MGTDREDSAAHWRERAACLNTEDPDLFFPVGSGVLTFEQTNEAKA
                     VCAHCPVMMQCLTWALRAGRVDGIWGGTTEIERRRMKRRHDQMVTG*"
     CDS             10651..11486
                     /protein_domains="PF12697"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397250"
                     /pseudo=False
                     /translation="MHRRSLSRRTPLTLLATATVGAALFAASVGPASAEKADAPQHPKP
                     TVVLVHGAFADSTSWNGVVKELKEEGYPVVAAANPLRGLSSDAAYVRELVASIDGPVVL
                     AGHSYGGAVITNAARGADNVKALVYLAAFMPDKGESAAALAEKFPGSSLGQALRPVPVH
                     LPDGSQGADLYIDQKKFPQQFAADVSRNTARLMAVTQRPVTDVALGEESGEPAWKTVPS
                     WTMVASEDLNIPPRTQQFMAKRAKSHTVEVEASHAVTVSQPDDVAELIERAARATR*"
     CDS             complement(11591..12180)
                     /protein_domains="PF04264"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397251"
                     /pseudo=False
                     /translation="MSISNDSTRVPPLAGLTGVYVIDPVHSTIGFSVRHAMITNVRGRF
                     TAFEGLLKLDGSRPSRSEAYLSVQTGSLETGNGERDAHLTGPDFLDSSTFPLMSFRSTG
                     CLDAGGGRFRVSGYLRIKDIELPIRLDLELGGASRDAAGNHRVGFEGSAVLRRADWGLD
                     RNAGPAAGGALIDDKVKLILDVSAVRLNQALAA*"
     CDS             complement(12346..13091)
                     /protein_domains="PF05368"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397252"
                     /pseudo=False
                     /translation="MKVVVIGGTGLIGSKLVAQLDEQGHEAVAAAPNTGVNTLTGEGLA
                     EVLDGASVVVDVSNSPSFEEKAVMDFFRTSTTNLLKAEAEAGCTHHVALSVVGTDRLPD
                     SAYFRAKQAQEELIKSSGMPYSIVHATQFFEFVKAIAADATDGDTVRLSPAKIQPMVSD
                     DVAAAVARAAVGTPVNGLVEVAGPEVFGLDELIRIGLAAQDDPRTVVADERATYFGAEL
                     KETSLLPGPDAHIAETKFADWLARQR*"
     CDS             complement(13314..14536)
                     /protein_domains="PF07992"
                     /protein_domains="PF14759"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397253"
                     /pseudo=False
                     /translation="VNTFVIVGGGLAAGKAAEALRENGHDGPLVIIGDENEKPYIRPPL
                     SKGYLLGKEERDSIFVHPDDWYREHEVDLLLDTRARAFDWRARTVDLEDGRQIPYDKLL
                     LATGSSPRRLTIPGAELDNVLYLRRVGDSERLKSAFTAGAKIVVIGGGWIGLETAAAAR
                     TAGGDVTVLEHGELPLLKVLGREAAEVFAELHTDHGVQLLPNVQVESLTGTAGRVDGVR
                     LADGRHLAADAVVVGIGITPNVQLAQEAGLDVRNGIVTDAHLRTSVADVYAAGDVANAF
                     HPRFDRHLRVEHWANALNQPRVAALSMLGKDAVYDRLPYFYTDQYDLGMEYTGYVEPGG
                     YDRVVFRGDVGKREFIAFWMAGNRVLAGMNVNVWDVVDPIRDLITSDSDVDDPRLADPD
                     VPLDRVAR*"
     CDS             complement(14683..15164)
                     /protein_domains="PF07883"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397254"
                     /pseudo=False
                     /translation="MSYPPQVYMGETGEISAKYRPVSTPPELGRPGKGAYYYLATTATT
                     RGEFGLYRVEMTARAGGPKTHFHKSISESFFILSGTVRLYDGAQWVDARQGDFLHVPQG
                     GLHAFRNDSDELAEMLLLFTPGAPREEYFEKLPEMGDATDEERAQFFVKHDSYFVE*"
     CDS             complement(15442..15914)
                     /protein_domains="PF02627"
                     /protein_domains="TIGR00778"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6397255"
                     /pseudo=False
                     /translation="VEARLNYFGNPFAGKVLRHINSANKVIEESLLPGTIQELVKIRAS
                     QINGCGFCTDMHTKDATAAGETSQRLNLVAAWREATVFTEAERAALEIAEQGTRIADAA
                     GGVSDEAWANATKHFDEEQLVALISLVAVINAYNRINVINQQPAGAYKPGMFG*"
ORIGIN
        1 atgagcatca cggcagacag cgaagcggtc ctgcgcggcg tcctggacca gtggaaggcc
       61 gccatcgagc ggcacgatcc ggggcaggtc gccgcccgct tcaccgagga cgcgatcttc
      121 caggggctgc acccctacag cgtggggcgt ccgggggtcg cggcgtacta cgactcccag
      181 ccggccggcc tgtcaccggc gtaccggatc cgggagacca ggcgcctcgc ggacgatctc
      241 gtcctcggct atgtgaacgt cgagttctcg atcccggacc ggcccacggt cgacgtccac
      301 ctgggcgtgc tgctgaagca cacggacggt gactggtaca tcagccacta ccaggtctcc
      361 cgcctcgacg ggtgacgctc cgggccggcg gacgtgcgcg gcaccggacc acggtccggg
      421 acacgcccgc cggccggcgg tgccgcgcga tggttcaggg cgcggtgaac agggtgggga
      481 agcgcgggcc gagccagggt ttgcgccccc aggtgaggac ctgcccccgg gcgatggcac
      541 gccaggggtt gcggcggccc agcgcgatga gcaggaaggc caccgggtcg atgaggatgg
      601 tgcagtcagc ccgttccatc ggccccgcga cgacgtgcac gtcgccgtcg gccaggccga
      661 ccccgaacgg ggagccgtcg cggaggcgga cggtgtagcg cgccgtgagg ccggcggtgg
      721 cggccttgtc ggcgacggcc ggcatgacgg cgagcatgaa cggcatgcac agctcgaccc
      781 ggtcgcggtc gatcatgtgc gggcggcgga gcgcacgagc gaggtcgtag ccgtggccga
      841 gcatgtgtgt gagcaggtag gacgcgagca ccgcccggtt catcgggccg agcggtgtga
      901 cgagcgcggt accgctgtcg gacgtggcgt cctcggcccg ttccaccgcc ttcaggaaca
      961 cctcggtccg ctccgcgatc atcgccgcga gcggttcggc ccgacgctcc tcgaacgcgt
     1021 ccagggcccg cgcgttggcc gccgccagac tctgcggcgt tccgtcgccg taggggcgtt
     1081 cgcgaccgga cgcgaggtcg gccatcagct cgttggcctg cgccagatgc gcggcgacct
     1141 cgccgaccga ccactccaga ccgggaacgg ggatcgccgt gtcgggcacg tcgcgcagca
     1201 gtgcggctat ctcctcggcg gtcgcgcgga gcgcctcggc gagtccttcg ggcagcggcc
     1261 cggtcatgtc ctgccgcacg gtcggttgca cgtcgctcgt tccctttccg cctgccgcgt
     1321 cctcgtcgcg tacgggggcg cgccgcggta cccaatcaga cgccgggggc gcgcgacaag
     1381 gcttcgcgcg ccgcgtacga cggtccgtgc cggagcacgt ggggcagatg cggacaagtg
     1441 gcccgccgcg gtcagccctt gggccccctt ctgctcgccc gcgcatcgtg gtgggaggaa
     1501 ggagggctga tcgaccgggg gcagcgcgcc gaggaactgg ccgtcgtccg taccgaccga
     1561 gcgccggagc cgggcgacgt gccctcggcg cccgcccgag gcacacgaac cctgtgtgag
     1621 tgacggtgcc cgggtactcg gtgagtccgg caccggcgca tcgccgtccg gtgatgtgcc
     1681 gtcggtgcac ggagccgctc gatcgtggcc ggcccgtacg gcagtggatg ccgacccggc
     1741 gccggccacc gtatggaggc acagccatga gcatggtgaa ggaatcgatc gacgtcgccg
     1801 tcccggtgac gaccgcgtac aaccagtgga cgcagttcga ggagttcccg aacttcatgg
     1861 aaggcgtcga agaggtccgg caggtcgacg agcgccacaa ccactggacg acgaagatcg
     1921 gtggcgtgcg ccgggagttc gacaccgaga tcgtcgacca gttccccaac gagcgcatca
     1981 cctggcggac cgtcggcggc catcccgagc agcgcggcat ggtcagtttc caggccctgg
     2041 acgagaacca cacacgggtg gcactcgtca tggacgtcga tccctcgggg gccgcggaga
     2101 ggacggcgga catgaccggg atgatcgacc ggcgggtgaa gggcgacatg cggcacttca
     2161 aggagttcgt cgaggaccgc ggcggtgaat cgggagagtg gcacggccgg atccgtcccg
     2221 gtcagatgtg acggccaggg cgagcatgcg tcggtagagc acaccccggt cgggcaaggc
     2281 ccggacgagg tacgagtcgg tccggtggag ccggacggac atccgcgagg acggcgcccc
     2341 ggaccgggca cgtcacttcg ctgcggggtg gccaccgggc ggggtgcacg gtctcatcgc
     2401 ggggtggccg ccaggacccg tacccggtgc cacccggacc ggcacggcgg ctgccgcgca
     2461 tgcacctgtc gcgcacgcac ccggcgcgcg gaccgccggg tgcgtgcgtg tgacctcagg
     2521 gccggggccg ggagggttcc accttgtcgc actgggggca gagcagccgg cgggcgggtt
     2581 gtggctggct gcgactgccc atgcctgcct gctgttgcag ttcctgagtc cttaggcgca
     2641 catgatcggc gcagatcccc gccccgcagc gttggcacac gccctcggcg gttgtggtcg
     2701 cgccggattg cgtgctgcat tcgtagcagt tcatcgaggc actccgactg ttcgcagcgc
     2761 ggtgggggag acccttccgg gtcagcggtc ccgggcacgc tctcactcaa cagtgtgccg
     2821 tgtgtgcccc ctgatgtcgc cgcgacggga cggcacgccc gcgccggtcg ccgcgcgcgc
     2881 cgcccagaag gtcactccgc tgcgacgtcg tgctcctcca ccggcggcat gaaagcccgc
     2941 agccaccgtt ccgtctgggc gacgtgggcc tgggcggcgc cggccgccga gacggggtcg
     3001 cggtcggcga tagcggtggc gaggacatgg tggtcctcgt cgctcttgcg gcgcatccgc
     3061 gggccttcgg gcagtgtgaa cacctggtac ttgcgggacc gggcgcggaa caccgccagc
     3121 agggtcgcca gcgtggggtt gccgccgatc cgggcgatct ccgcgtggaa gcggtggtcg
     3181 agttcggagg cctcggcggg gtcctcggtg gcctccatct cctcgatgag ggagaacagc
     3241 gtgcgcaccg cctcgggcgt gcagcgcgcc gcggcctggg cggccacgtg ggcctccagc
     3301 acgcgccgga tctcgtagac ctccaacagg cccgacagcg gcaggagttc cagggtgagc
     3361 gagaggctgc cgatgacgtc ctcgggcctg agctgggaga cgtaggtacc ggagccgtgc
     3421 cgcggttcga tgacgcccag ggcggcgagc atccgcaccg cctcgcgcaa cgacccgcgc
     3481 gacacaccca gttccgcaca caggtcgccc tcgggaggaa tgcggtcacc cggccccaga
     3541 cgtcctgtcg cgatcatgtg ccgtaggccg tggaacgcct tgtcgactgc ggacatgcga
     3601 cccctcttct tcccctgaac gggccgccgg agtcgccgga ggcctcggcg cactgtagcg
     3661 agtcatcaaa tgtcccggat gtatcgccca gaagtcatca gatgactttc ctcgtacgac
     3721 ccttgtcgag accgaaaaac ccatgccagg atgccgagtc atcatacgtg tccacgcagg
     3781 acgtctgatt tctgcgggca cgtccagttc ctcagatgtg gagtgctgtg agcgagaccg
     3841 aggtgaccac cgcgccgcgc ccgctgctgc tggccgacgg acggcccgcc gaccgcgcgt
     3901 ggtccctgga ccccggaatg aagcacctga accacggttc gttcggggcg gttccgctgc
     3961 aggcgcagga gcggcaggaa ctgctgcgcg tggagatgga acgctcgccc gtcgtgtggt
     4021 tcccggcgct gccgcagcgg atcgccgcca cccgcgtcga cctcgcggcc ttcctgcgcg
     4081 tcgcggccga cgacctcgcc gtggtgccca acgcgagcgc cggagccagt gtggtcttcg
     4141 ccgccctcga ccgggttcgt ggcggggaga tcgtcgtcac cgaccacggt tacggggccg
     4201 tcaccatggg ggccgagcgg ctggcgcgcc gctggggcgg ccgggtgcgc accgccgagg
     4261 tgcccctgga cgcgaacgag gagcaggcgt acgaggccgt gtgcgccgaa ctcggcgacg
     4321 acaccgacct cgtcgtggtc gatcagatca cctcggccac cgcacgccgg atgccggtgg
     4381 agcggatcgg cgcggaggcg caccgccgcg gcatcccgat gctggtcgac ggcgcccacg
     4441 cgcccggtct gctggccgcc ccgctcgccg gtgcgacata cgacttctgg gtcggcaacc
     4501 tgcacaagtg gggctgcgcc ccgcgcggca ccgcggcgct gatcgcccgc ggcccgctgc
     4561 gcgaccggct ctaccccctg atcgactcct ggggtgcggc cgacccctac cccgaccgct
     4621 tcgaccagca gggcaccatc gacgccaccg cctgcctcgc ggcccccacc gcgctcgact
     4681 tcgtcgaacg tacctgggga tggaccgccg cccgcgacta catgagcgag ctggccgact
     4741 acggcgccca tgtcatcggc accgctttcg ccgaactcac cggcagggac agccgggtcg
     4801 acgtcggcct gccggtgccc ggcatgcgcc tggtgcggct gccggagggc ctgggcaccg
     4861 gccgggtcga ggccgacgcg ctgcgcgacc gggcggcggc cgagctgggc gtggaagcgg
     4921 cgttcaccag cttcggcggc acgggctacc tgcggctgtc cgcccacgtc tacaacaccg
     4981 ccgccgacta cgagtacttc gccgaggaat gcgtccccgt cctcggtgag tgggcccgca
     5041 cggcccgcga gcagcaccgc gcgccgtagg cgcccgttcc cctgccgctg tcggcgcggc
     5101 cgtcatccga ggaagatcca gggaagaggt cagcacaatg agaagaagga cggcagctct
     5161 cgctctgggc acagccgccg cgatggtcct gaccggctgc tccaccatga gccccgatgc
     5221 gagcggaacg gtcactctca acatggtgga gagcctgacc aatccgaccc gcaccgatct
     5281 gctgaaggac ctgatcgccg atttccagca gcagaacccg aagatcaagg tcaatctgat
     5341 ctccccgccg accgaacagg ccgaccagaa gctccagcag atgcttcagt cgggcagcgg
     5401 cgtggacgtc ctggaggtcc gggacatcac ggtcggaccg tggtcgaaca acggctggct
     5461 gtacgacatg aagaaggacc tggacggctg gaagggctgg ccggccatga cggagaacgc
     5521 cgtcaaagcc gcccgcaacg acgagggcaa gacgtacttc gtcccgtacg gcttctacgg
     5581 tctgagcctc ttctaccgca ccgacctgat cgagaaggcc ggcttcagcg agccgcccgc
     5641 cacctgggcg gaactgctgg agcaggcctc ggccgtccac gacccctccc agcgccgcta
     5701 cggttacgcc ttccgcggtg gctccaacgc caacagcaac gccaccgccg tcatcgaggc
     5761 ctacgtcgcc gaccaggtcg acccggccaa cggctacaag ctcaagaacg gccgtacgat
     5821 cttctccgcg cccgaggcgc aggacgccct ggagacgtat ctcaagcttt tccagcgggc
     5881 ctcgccgaag tcgtcggtct cctggggcta tccggagatg gtggaggcgt tctccaacgg
     5941 ctccacggcc ttcctgctgc aggaccccga ggtgatcgcc acggtctcgg agtccaagtc
     6001 gatctcggag ggccagtggg gcaccgcccc gctggtggcc ggtcccggtg gcaagacggt
     6061 ccagccgctg gccacggcgg gatggggcgt cgcgcagggc ggcaagcaca agcccgaggc
     6121 cgtcaagctg gtccagttcc tgtcccaggg ggaggcgtcg acgacgttca ccaagaagaa
     6181 cagcctggtg ccgatcctga agtcggccac cgccgacccg ttctaccgga cgggtccctg
     6241 ggccagctac gtcaccatga ccgagcagcc ggagaagtac ctggtggtca cccagccgcg
     6301 cggggtggcg tggtggaccg agtgggagca gcgggccgac accgacgtgc agaagctggc
     6361 gctcggcaag acgacgccca aggagctgct ggcgagctgg gacgcgtact ggaccgagaa
     6421 gtggcggcag gagcagtagt catgtccgtc gcgtccacac cgacgaagac atcgacgccc
     6481 ggccggggcg gcgccacccg tgcgggcggc gccccccgag gggggcgccg caagcgggag
     6541 ttcaccaccc ggcgtggtgc gctgatcgcc gccttcatgg cgccggccgc ggtcttcgtg
     6601 gcggtcttca cgtactaccc gatgatcgcg ggcggccaga tggccttccg caactggaag
     6661 ctgaccgatc tgaccgacac ctcctgggtg ggtctgaaga acttcgcgga cgtgttcgcc
     6721 gaccccgcct ggggaacggt gctgggcaac accgcggtgt gggtggtcgg ttcgatcgtg
     6781 ccccagctgg tcatcgggtt cgcactcgcc ctgtggctgc gccgccgctt ccggttccgg
     6841 gggctctacc aggcgctgat cttcttcccg tgggcgatct cgggcttcct catcggcatc
     6901 ctgttccgct ggatgttcaa cagtgagttc ggcgtcgtca acgacctgct ccagaaggcc
     6961 gggctgatcg acgagccgat cgcctggctg gcggatccgg acacggcgat ggtggcggtg
     7021 ctgatcgcca acatctggta cggcgtcacc ttcttcacga tcatgatcct ggccgctctc
     7081 cagtcgatcc ccgacgagtt gtacgaggcg gccgcgctgg acggcgcggg caaggcgcgc
     7141 accctgttcc gcatcacgat cccgtacatc cggacgacgc tggtgctcac cgtgctgctc
     7201 agggtgatct ggatcttcaa cttcccggac ctgatcttcg gtatgaccgg cggcgggccg
     7261 aacgacgaga cgcacatcgt gaccacctgg atgatccaga tcacgcagca gggcgactac
     7321 ggcagggctt ccgcactcgg cctcctcgtg gtgggcgcgc tgctgatgtt cgccgtgttc
     7381 ttcctgctgg ccacgcgtga gaagaaaggg gtgaggtcgt gatcggcaag gagaccgcgg
     7441 ccggccgggc cggcaagttc accttcctgg gcctgtggct ggccttcacc gtcttccccc
     7501 tctactggat cacggcgacc tccttcaagg cgcccggcga catcttccgc ttcccgatcg
     7561 actactggcc cgagcacctg tcgctggaga actacagcgg cctgttcgcc accgccgact
     7621 tcgggaccta cctcgtcaac agcctcgtcg tggccaccgt cgcgggtgcg gtggcgacgg
     7681 tgatctcgat gctctcggcg tacgtcctgg cccgtttcga gttccgcacc aaatccgctc
     7741 tcctcatggc cgccctcgtc acccagatga ttccgtcgtt catcgctctg ggcccgctgt
     7801 atctgctgat gacggatctg aaactggtcg acaaccacct cggactgatc ctggtctaca
     7861 tcgccgtgtg cattccgttc tgcacggtga tgctgcgcgg gttcttcgag aacatcccgg
     7921 acgcgttgga ggaggccgcc atgatcgacg gactgtcccg gttcggagcg ctgttccggg
     7981 tgctgctgcc ggtgatgcgt ccgggtatcg tggccgcgtt catcttcaac ttcgtcaact
     8041 gctggaatga actcttcctg tcggtgacgc tgatgaacag cgacagcaac aagacgattc
     8101 ccaccgccct gaacggcttc atctccagtt tcaacatcga ctggggatcg atgtccgcgg
     8161 cggccgtgct gaccatcctg ccgacgatgc tgctgttcgc gttcgccagc cgtcacatcg
     8221 tccaaggcct cacctccggt gcggtgaagg ggtagtcggg ctaagccgtc aaaggcctgt
     8281 cacagcaacc acctctgcct tgtctaattg gtgtcggaca acgagcagag gaagacatgc
     8341 gcgagatcct gatcgtgggt ggcgggtacg cgggtttcta caccgcgtgg ggcctcgaaa
     8401 agaggctgcg gaaaggggag gcgcgcgtca ctgtcgtcga ccctcgtccc tacatgactt
     8461 accagccctt ccttccggag gtgacggccg ggtcgatcga ggcgcgccat gccgccgtgt
     8521 cgctgcggcg ccatctgcac agcacccggc tgatggcggg cagcgtgatc gagatcagca
     8581 acgcggatcg gacggtcacc gtccgatccg cgaacggcgc cgaacagcag ctgcgttacg
     8641 acatcctcgt ggtcaccgcc ggcgcggtga cccgcacctt ccccgttccc ggactcgcgc
     8701 agcacgcgat cggcctgaag cacgtggaag aggcggtggc catccgcgac cgcctcatga
     8761 ccgccttcga ccaggcggcg tccctgcctc ccggcccgga acgccgcaag ctgctcaccg
     8821 tcaccttcgt gggcggtggg ttctcgggcg tcgagggctt cggcgaactg ctgtcgctcg
     8881 cgacggcgat gctcaagtcc tacccggagc tgagcatgga cgacctgtcc ttccacctgg
     8941 tcgaggcccg gggccggatc ctccccgagg tgaccgacga acccggttcc tgggtggtgc
     9001 ggtccttgga acgccgtggc gcacacgtcc acctgaacac ccagctgctc tccgtcgagg
     9061 acgggcacgt cgtcctctcc aacgggcagg agttcgattc ggcgctggtc gtctggaccg
     9121 ccggcaacgc cgcgaacccg gtcgtgcaca accacacgga tctgccggtc gaccagcgcg
     9181 gccttctcgt ggtccggccc gacctgcggg tgggaaccga cagcgagccc gtgaaggatg
     9241 tgtgggcggc cggcgacgac gccgcggttc ccgacctggc cgtaccgggg gcgtacacgg
     9301 tgccgaacgc ccagcatgcc gtccggcagg gcaagcggct cgcgaagaac atcgtggccg
     9361 acctgcgcgg gggcaagacg cggaactacc gtcacagcag tctcggtgtg gtggcgacgc
     9421 tcggcctggg gcgaggcatc ttccagtaca agcgcatcgt catcaagggg ctgcccgcct
     9481 ggctgatgca ccgcggctac cacgtcctgg ccgtgcccac ctgggagcgc aaggtccgtg
     9541 tgctcgcggt gtggctcacc gccgccgtgt acggccggga cctggtctcc ctcgcctccg
     9601 tgcagcaccc gcgggacgcg ttcgtcacga gtggcgaccc ggagcggtcc ggcaagagcc
     9661 ggcaggacga tcgcgccgcc gcctgaccgg atgtccacag ggccgcgggg ctcaccgcac
     9721 ggtgagcccc gcggccctgc cgcgctcccg cggaccgcgc cgacgcccgg cgggtttccg
     9781 agccgttccc agggccgtcc accgtctccc ggcacacccg gcgcggccct cggtgcgcac
     9841 gtgtccggga gcgccggctc cttcgtgaag tcgtgtgtca cacaagagcc cgtcgtcttg
     9901 tctcacttct cggactcgac agctctcacg agaatgagaa aggccgtgat cggcccatgg
     9961 gcactgaccg agaagattcc gccgcgcact ggcgcgaaag ggcggcctgc ctcaacacgg
    10021 aagaccccga tttgttcttc ccggtgggaa gcggcgtcct gacgttcgaa cagaccaatg
    10081 aggccaaagc cgtgtgtgcc cattgccctg tcatgatgca gtgcctgacc tgggctctgc
    10141 gagcggggcg cgtggacgga atctggggtg gtacgacgga gatcgaacgt cgccggatga
    10201 agcggcgtca tgatcaaatg gtcaccggct gaccgctcgc ccgtcgatgt gtgaagaacc
    10261 ggccgtaccg gagaattcct ccccggcacg ccgggaatca gccgtaccgg aaaatccttc
    10321 cccgccccgc cgggaatcgg gaacggctgt cacaccttga ccggttcgcc tgtcataaga
    10381 gtgagtgcgg gaaagaacct gccggcccga aaagggctcc gctctttttt cctgaacccg
    10441 cccccctctc ggtccggtgt gggccgtgac tgccgcccgg cggcgggctg tcgaccctgt
    10501 gcgagtccgc gccgcggcag tcgggagaac ggcggtgctc gaccggcact cgtccgcacc
    10561 acccaagaga ccagcagcag agaagctgct acggcggccg tgccgctcca ccgcgcacgg
    10621 ctgaaatctt cgcctcgaaa ggcctgttca tgcaccgtcg atcgctgagc cgacgcaccc
    10681 ccctcaccct cttggccacc gccacggtcg gcgccgccct gttcgccgcg tcggtcggtc
    10741 cggccagcgc cgagaaggcc gacgccccgc agcaccccaa gccgaccgtc gtcctggtgc
    10801 acggcgcgtt cgccgactcc accagctgga acggcgtcgt caaggagctg aaggaggagg
    10861 gctacccggt cgtcgcggcc gccaacccgc tgcgcggcct gagcagcgac gccgcctacg
    10921 tccgtgagct cgtggcgagc atcgacggcc ccgtcgtgct cgccggccac tcctacggcg
    10981 gagcggtcat caccaatgcc gcccgcggcg ccgacaacgt caaagcgctc gtctacctcg
    11041 ccgcgttcat gcccgacaag ggagagagcg cggccgcact ggcggagaag ttcccgggca
    11101 gttccctcgg ccaggcgctg cgccccgttc cggtgcatct gccggacggt tcccagggag
    11161 ccgacctcta catcgaccag aagaagttcc cccagcagtt cgccgcggac gtctcccgga
    11221 acaccgcccg gctcatggcc gtcacccagc gaccggtgac cgacgtggcc ctgggggagg
    11281 agtccggcga gccggcctgg aagaccgttc cgtcctggac catggtggcc tccgaggacc
    11341 tcaacatccc gccgcggacg cagcagttca tggcgaagcg cgcgaagtcg cacacggtgg
    11401 aggtcgaggc ctcgcacgcg gtgaccgtgt cgcagcccga cgacgtcgcc gagctcatcg
    11461 agcgggcggc gcgggcgacc cgctgaccgg tgtgcaccac agggcggggc ggcagcgatg
    11521 ccgccccgcc cgcctgtccc gtcgtggggt ccgcacggcc ggacgcgacg cgcggaccgg
    11581 ccgaggcctt caggcggcca acgcctggtt caggcgtacg gcggagacgt cgaggatcag
    11641 cttcaccttg tcgtcgatca gcgcgccacc cgccgccggt cccgcgttcc ggtcgagtcc
    11701 ccagtcggcg cgtcgcagaa cggccgaacc ctcgaagccg acacggtggt tgccggcggc
    11761 gtcccggctc gcgccgccga gttcgaggtc gaggcgaatc ggcagttcga tgtccttgat
    11821 ccggaggtac cccgacacgc ggaaccggcc gccaccggcg tccaggcatc cggtggagcg
    11881 gaagctcatc agggggaagg tcgacgagtc gaggaagtcc gggccggtga ggtgcgcgtc
    11941 gcgctccccg ttgccggtct ccaagctgcc cgtctggacg ctgaggtagg cctcggaccg
    12001 gctcgggcgc gacccgtcga gcttgaggag cccttcgaac gcggtgaatc tgccgcgcac
    12061 gttggtgatc atggcgtgtc ggacggagaa gccgatcgtg ctgtggaccg ggtcgatgac
    12121 gtacaccccg gtcagtcccg cgaggggcgg gacacgcgtg ctgtcgttag atatggacat
    12181 gacaagtctg agttcctcgg tgcgtgaacc tcgggcaggg gtcggtccgg acgcggtgcg
    12241 gccgtccggt gggacgggac tgcggccccg gtggacagag gccggacggc gaatggggaa
    12301 cgggggtggc gccggccgtc cggcgggagc cacccccgtc ggggtcagcg ctgccgggcg
    12361 agccagtccg cgaacttggt ctcggcgatg tgcgcgtcgg gaccgggcag gagcgaggtc
    12421 tccttcagtt cggccccgaa gtacgtggcg cgctcgtcgg cgaccacggt gcgggggtcg
    12481 tcctgcgcgg cgaggccgat gcggatgagc tcgtcgagac cgaagacctc ggggccggcc
    12541 acctcgacca ggccgttgac cggggtgccg accgcggcgc gggcgacggc cgcggccacg
    12601 tcgtcggaga ccatcggctg gatcttggcc ggggacaggc gcacggtgtc accgtcggtg
    12661 gcgtcggcgg cgatcgcctt gacgaactcg aagaactgcg tggcgtggac gatggagtac
    12721 ggcatgccgg acgacttgat gagttcttcc tgggcctgct tggcgcggaa gtaggcgctg
    12781 tccgggagac ggtcggtgcc gaccacggac agtgccacgt ggtgcgtgca gccggcctcg
    12841 gcctccgcct tgaggaggtt ggtcgtggag gtgcggaaga agtccatgac ggccttctcc
    12901 tcgaacgagg gggagttgga cacgtcgacc acgacggacg cgccgtcgag gacctccgcc
    12961 aggccctcgc ccgtcagggt gttgacgccg gtgttcggtg cggccgcgac cgcctcgtgg
    13021 ccctgctcgt cgagctgtgc gaccagcttc gatccgatga gcccggttcc accgatcact
    13081 acgaccttca taaggaatac ctctcgaaag aatttggtgt ctgtatcaga gaaagacagg
    13141 acaactgctt cgtgtgtgac agggatcggg acggttcggg gaaacgtgtc cccgtcggcc
    13201 gtcccctgtc gccgtcggat cccgcggcgc cgcgctcagg cgcggcgggg gacagggcgt
    13261 accgtccgcc ccgccccgcc gacgtccggt caggtcaccg ctcgacgcgg ggtcaccgcg
    13321 cgacgcggtc caggggcacg tccgggtccg ccagacgtgg gtcgtcgacg tcggagtcgg
    13381 acgtgatgag gtcccggatc ggatcgacga cgtcccagac gttcacgttc atgcccgcca
    13441 ggacacggtt cccggccatc cagaacgcga tgaactcccg cttgcccacg tcgccgcgga
    13501 agacgacacg gtcgtagccg cccggttcca cgtagcccgt gtactccata ccgaggtcgt
    13561 actggtcggt gtagaagtac ggcagcctgt cgtacacggc gtccttgccg agcatgctga
    13621 gcgcggccac gcggggctgg ttcaacgcgt tcgcccagtg ctcgacccgc agatggcggt
    13681 cgaagcgcgg gtggaaggcg ttggcgacgt cgccggcggc gtacacatcg gccaccgagg
    13741 tccgcaggtg cgcgtcggtg acgatgccgt tccgcacgtc caggcccgcc tcctgggcga
    13801 gttggacgtt cggcgtgatg ccgatgccca cgaccacggc gtccgcggcc aggtgccggc
    13861 cgtcggcgag ccgtacgccg tccacccggc ccgcggtgcc ggtgagggat tccacctgca
    13921 cgttgggcag gagctggaca ccgtgatcgg tgtgcagttc ggcgaacacc tcggcggcct
    13981 cgcgtccgag caccttcagc agggggagct cgccgtgctc caggacggtg acgtcaccgc
    14041 cggccgtgcg ggcggccgcg gcggtttcga gaccgatcca gccgccaccg atgacgacga
    14101 tcttcgctcc cgccgtgaag gcggacttga gccgctcgct gtcgcccacc cggcgcagat
    14161 agaggacgtt gtccagctcc gctccgggga tcgtcagccg gcgcggggac gagccggtgg
    14221 ccagcagcag cttgtcgtac gggatctggc gcccgtcctc gaggtccacg gtccgggcgc
    14281 gccagtcgaa cgcccgcgcg cgggtgtcca gcagcaggtc gacctcgtgc tcgcggtacc
    14341 agtcgtccgg atgcacgaag atcgaatcgc gctcctcctt gccgaggagg taccccttgg
    14401 agagcggcgg ccggatgtag ggcttctcgt tctcgtcgcc gatgatgacg agcgggccgt
    14461 catggccgtt ttcccgcagg gcttccgcgg ccttgccggc ggcgagaccg ccgccgacga
    14521 tcacgaaggt attcacaggg ttcctcatct ccgatgtcgc gtgccgcgag tcgttgggaa
    14581 gatcactcac tgatcagacc gggtggccct acatcctgtg acagcccggc cgaaaggcgg
    14641 gggagagaca cgcgccgacc gcacggcctc cggctgttcg actattcgac gaagtaggag
    14701 tcgtgcttca cgaagaactg ggcccgttcc tcgtcggtgg cgtcacccat ctccgggagt
    14761 ttctcgaagt actcctcacg cggcgctccg ggcgtgaaga ggagcagcat ttccgcgagc
    14821 tcgtcggagt cgttccggaa cgcgtggagt ccaccctgag gcacatgcag gaagtcaccc
    14881 tgccgagcgt cgacccattg tgcgccgtcg tagagccgca ccgtaccgct caggatgaag
    14941 aacgactccg agatggattt gtggaaatga gtcttggggc cgcccgcccg tgcggtcatc
    15001 tcgaccctgt acagtccgaa ttcgccccgg gtggtcgcgg tggtcgccaa atagtagtag
    15061 gcgccctttc ccggtctgcc gagttccggc ggagtgctca cggggcggta tttcgcgctg
    15121 atctcgccgg tctctcccat gtacacctgc ggggggtatg acatgaagac catctcccgt
    15181 tgatcggttg cgcaacgaga cgccgacgaa atatgcgcgc accatcaccg tggccgcgga
    15241 ccaccggcgt ctctcggtct tccgaccggg tgcgcccctg cggggagaga ccgagtactc
    15301 ccagggtaga gacatcgccg caacgccgcg cagtcgatca ggcggccccg ggaatcggcg
    15361 gctccgggtt gtccgtctcc gcgccgtagg tcggggcggc gtggagacgg acggtgattg
    15421 tccggctcgg gctggtccga tcagccgaac ataccgggct tgtaagcacc ggcaggctgc
    15481 tggttgatga cgttgatccg gttgtaggcg ttgatgaccg cgaccagcga gatcagcgcg
    15541 acgagctgct cctcgtcgaa gtgcttggtg gcgttcgccc aggcctcgtc gctgacaccg
    15601 cccgcggcgt cggcaatgcg ggtgccctgc tcggcgatct ccagggcggc gcgctcggcc
    15661 tcggtgaaga ccgtggcctc tcgccaggcc gcgaccaggt tgaggcgctg cgaggtctcg
    15721 cccgcggcgg tggcgtcctt ggtgtgcatg tcggtgcaga aaccgcagcc gttgatctgg
    15781 ctcgcgcgga tcttcacgag ttcctggatc gtgcccggca gcaaggattc ctcgatgacc
    15841 ttgttggccg agttgatgtg ccgcagcacc tttccggcga aggggttacc gaagtagttg
    15901 agtcgcgctt ccac
//
