LOCUS       reptomyces_RBGC_147511 15981 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_147511
VERSION     Streptomyces_RBGC_147511
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000721605.1
  ORGANISM  GCF_000721605.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1050
                     /protein_domains="PF00005"
                     /protein_domains="PF08352"
                     /protein_domains="TIGR01727"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776042"
                     /pseudo=False
                     /translation="MAEPVLEVSGLVKHYPLTRGVVFRKQVGAVRAVDGVDFTLGRGET
                     LGIVGESGCGKSTVARMLVNLERPTAGSIRYKGEDITRLSGKALKAVRRNIQMVFQDPY
                     TSLNPRMTVGDIVGEPYDIHPEAAPKGDRRRRVQDLLDVVGLDPDYVNRYPHQFSGGQR
                     QRIGIARGLALRPEVIVADEPVSALDVSVQAQVVNLMDRLRAEFGLAYVFIAHDLSIVR
                     HLSDRVAVMYLGRIVETGTDTEIYEHPTHPYTQALLSAVPVPDPAAREHRERIVLSGDV
                     PSPADVPSGCRFRTRCRKARERCAREVPALAVPAWFRTAGGPAAHDSACHFAEEKVLVP
                     VEGYGDGPG*"
     CDS             complement(1152..3289)
                     /protein_domains="PF00326"
                     /protein_domains="PF00930"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776043"
                     /pseudo=False
                     /translation="MTTETDSFPRRHARTLRFTLGAPRSFSVAPDGSRVVFLRSGSGTD
                     RANSLWVLDTEGGGERVAADPRALLGGASENLSPEERARRERSREGGAGIVGYATDAAV
                     ELASFALSGRLFTAELRAGTARELRVPGPVIDPRPSPDGRYVAYASRGALRVVGAEGTD
                     ERALATPESENVIYGLAEFVAAEEMGRSRGFWWAPESDRLLVARVDDTPVRRWWISDPA
                     HPEREPQRVAYPAAGTPNADVRLFVIDLDGARTEVSWDRARYPYLAHVHWSAAGAPLLL
                     VQARDQRAALILAVDPDSGATRMVHADEDPIWLELFPGVPCWSPSGQLVRIADEGGARR
                     LAVGERPLTGAQLHIRAVLDVSDDDVLVSASAGEEAAGPEIGEVHVYRVNELGVERVSQ
                     EPGVHSAVRAGGVTVLVSAVLDRPGSRVQVLRDGKPMATVPSYAEDPGMSPRVTLTQGG
                     ARRIPCAVLMPRDYAGDSPLPVLMDPYGGPHGQRVLAAHNPHLTSQWFADQGFAVIVAD
                     GRGTPGRSPAWEKSVRDDIAALVVQDQVDALQALAADFPLDLDRVAVRGWSFGGYLAAL
                     AALRRPDVFHAAVVGAPVTDLRLYDTHYQERYIGHPDEQPEVYRRNSVIDDAGLVDAAG
                     PHRPMMIIHGLADDNVVVAHSLRLSSALLAAGRPHEVLPLSGVTHMTPQEEVAENLLRL
                     QLGFLKRSLGLTNGDEPR*"
     CDS             3477..3670
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_9776044"
                     /pseudo=False
                     /translation="VALSISAVVLLAIIVFLLIKKSGLKAGHAVVCMLLGFYLASSTIA
                     PTISELTTNIAGMIGSINF*"
     CDS             complement(3587..3753)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776045"
                     /pseudo=False
                     /translation="MPEERVGRGLRLGPGTCLGTRPEDGTVAQKLMLPIIPAMFVVSSL
                     MVGAIVDEAR*"
     CDS             4049..5475
                     /protein_domains="PF01425"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776046"
                     /pseudo=False
                     /translation="VTTSEEQSEARTRVHVFRDDALGDHDAVGLARAIRRREVGAAEAA
                     RDAAARVKAVEPRLNAVQTHLDVPAHGSDSGGLLAGVPTFVKDNTDYQGLPTGHGSAAF
                     APRAARRHAPFVRQFLSTGVTVLGKTRLPEFGFSPTTEYEDAEPVRNPWHTGRSAGGSS
                     GGSAALVAAGAVPIAHANDGGGSIRIPAACCGLVGLKPTRGRMVANEQGRRLPVDLVVD
                     GVVSRSVRDSAAFLAAAEKHWRNPKLPPVGLVEGPSERRLRIGFLLDSPNGVRSDADTR
                     AAVTETAERLERLGHTVEPVELSIDPHFTDDFLTYWGLLSFLIGVTGRTLGADFDRRRM
                     DGLSRGLRETYVRAWRTTPAVLRRLKRTREAYAAGFRGLDLILSPVLAHTTPPIGHLSP
                     TVPYATLIERLLNYVAFTPVDNVVGTPSLSLPSASTTPDGLPIGVMFSARPGAERTLLE
                     LAFALEADRPFRRLRDV*"
     CDS             complement(5691..6634)
                     /protein_domains="PF01636"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776047"
                     /pseudo=False
                     /translation="MVADGWDATRAWVEKGLTEAEHIEDAVRLRGGWTSEMRRLDVCGP
                     AGRRALVLRSFVKPFFVRHAEGLLNREAAVLRLLGGTDVPAAALVAVDATAQYCDHPSL
                     LMSLLPGTVRLSDKGADRRAELLARQLLRIHQVSVTAETRPRAYQAWTSSERVSLPEDT
                     ERPELWQWAVDVIRREPPAHRACFLHRDFHPGNVLFTGDGDGLRVSGVVDWVETSWGPA
                     DLDVAHCSTALALLHGVSAGMRFADLYVAAGGTLAEDSASHLYWRLLDALAFAPEAEKV
                     AVPWREVGRADLTPTLLTRRLEEYLQALFARCA*"
     CDS             complement(6769..7973)
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776048"
                     /pseudo=False
                     /translation="MLWLAGILVSLAGNSVFYFALGWAASEHGGTVAGLTLSAITLPRV
                     LLLLLGGAVSDRFSARRVLIAGDAAMLAFSLVLAAVAYHLGAPPVLLITAGIAVGVVDA
                     FYLPASGSMPRRLVEKEQLPRALSLRQIGGQVVNMGGGPLGGVLVGLAGLAGAALVNAV
                     TFALTLTVLVVVRPRHHVPPTRASSLLKDAMDGVRVAFSHPVLRPGLCLTGAAAGFLLP
                     VLPLLLPLLARQEQWGAGATGLAIGAQGVGMVAVTAVVVKRGPMGRPGLLSASALVLAG
                     LGVLALALAPGVAEATAASLVIGIGNGMFSAHIAPLILTATPESHLSRVQAVLVLVQSL
                     ALLLMNNLLGTLADLEGPTVVTAACATMLVGAGLLGLTSGPLRKDRTGLPPRLDPVSTP
                     ST*"
     CDS             complement(8330..8790)
                     /protein_domains="PF01243"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776049"
                     /pseudo=False
                     /translation="MQTTGIVRRQAAERRRDTLERLATERDVWVSTAHPDHGPHQVPLW
                     FLWDGRAVWVCTSATTATARNVREEPRVRLALPDTLDVVLLQGEAECFSDQDVPEDAAE
                     AFAAKFGWDPRTEEGSFLYVRVVPRSVRAWRGEPELRGRVIMRDGTWLE*"
     CDS             complement(8937..9079)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MAGDAEQAEGPRSASPCRDAPPPEKPHFAESVSSGQSNVIQTLKR
                     AG"
     CDS             complement(9103..9326)
                     /protein_domains="PF04149"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776050"
                     /pseudo=False
                     /translation="MSPEEPSGSDWRCTPSPMARSESSYSSGSEGDSCVEIAAEPGTVH
                     VRDSKNVEGPRLAFAPAAWAGFLPYAVEG*"
     CDS             9446..10200
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776051"
                     /pseudo=False
                     /translation="VTRTISCNQPTAARPHPEAPSRAVDRPGPSAAAEPQPHPHPQEPC
                     EERAPQQTRERRAPQEACEERGPQETRERRAPQEACEERGPQETRERRAPQEVCEGRGP
                     QETRERRAPRKPLPAVPRPACNVPALFRAATDLLADLHRHEPRLLLSTGDAAHLAPGVA
                     AWLERDVTPAAVRRALTADLPPEGVRRPAAFLAHRLAAQLPPPPPFRASAAPPAVRHPL
                     QNCDGCDRAFRAPHPGRCRACRTGLQEAA*"
     CDS             complement(10346..12135)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776052"
                     /pseudo=False
                     /translation="MTSDTHGSTAQLDEYRSHLGLAKQAGARKAIRELVLISDGGEALE
                     LAARFTPTAAYSSDALLRLWPTAADPDGFCEHLLAPAFAQEERTGLRLRRMTSLRGLRH
                     LTTLRTLEIDRCKEVTDLTELGALTGLTGLDLNGCTGVEDLAPLGRLTALTRLGLRRCR
                     TVEDVTPLLTLSRLRELDLSMTRVRSTQGFDAAFPVLEKLTLRGCRSFKDTRQLSGLTR
                     LTVLDLGWTGIRDLAGLHDVPAVTELDLRNCGQLRSLRGIDALTALSRLVIEDCPRLRT
                     VDGLGAHPHLQRVRIEGCPELTDVSAVSHLTRMSSLTIRGCERITSLEDAKELATLVSV
                     SLEDCAALRDFSALATLPRLERLYVVGCNRLHSLEALGSLPRLTELQVSGCRLLRSPGD
                     LGGLPALCKLRIENCPSLTDLDHLGGLPSLDKLYVDECHALGNVDGLAGSPASEVVLRR
                     LPALKSLRALGTCEGLRTLYLSECSRVTDIPAGPFEKLAVGHMSWKDLSRLAGQKQLRT
                     LDVAHLTELEDIGAVTGMPGLVRIDLSHCYALEDCTALFELPSLKTARVPLRMSLRTRQ
                     DPPHPLVAELTARGVTVPKP*"
     CDS             12208..13121
                     /protein_domains="PF02585"
                     /protein_domains="TIGR03445"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776053"
                     /pseudo=False
                     /translation="MTGVRGAGVEGPAPHRVEPMTELPDRRLLLVHAHPDDESINNGAT
                     MARYAAEGAHVTLVTCTLGERGEVIPPGLRHLSGAALGGHRLGELKDAMRALGVEDVRL
                     LGGAGRYCDSGMMGLPDNDDPGCFWQADVDRAAGLLAEVILEIRPQVLVTYDDDGGYGH
                     PDHIQAHRVAMRAVELAADGGWDIPKVYWNRVPRSVAEQAFARLDGDLPGLPFEKAAAV
                     GDVPGVVDDEQITTAIDGTAYAAAKAAAMRAHATQITVAEPYFVLSNELAQPLFTTEYY
                     ELVRGGRPGEREGDLFAGIGEAP*"
     CDS             13119..13531
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776054"
                     /pseudo=False
                     /translation="VSDRSPSVLAQPLRPPSAGRVVACLGLFLLGAVVGTAGALVQPAW
                     FPGGLLLALAAEAGLVLGATRALRSRAGGGWAAGGWTLVVILLTTSRPEGDFLFAAGGG
                     SYLFLLGGIAVAVICATLFSGRQPDGPPARLGK*"
     CDS             13727..15981
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_9776055"
                     /pseudo=False
                     /translation="LSRETDTPSSGPDGRGGAAYPSGTPPYGIPAIPDAGTDAGRSAAR
                     PEERKTETTLTTRVRINIPGSRPIPPVVVRKPVADAEGKSGTTDAEAAAPSPAPAADVA
                     ESPAQPAQPDGSDRPAAEEKPASDWFAPRKSGGGKGGPAGGSANGAGAPSGSGPAAGGA
                     PKAPSAPGGARPGGGVGSTGAPGGSLPGGTRGSGPTGATGATGGPVAPGHGGGTGSFDV
                     TEALAAGPAGPGTRPGTGHGDEPRRDDLPFFADEAPRPGRRGPQGPTGPTTGPATGSSP
                     VARQTGKGSGAPAVPGGSGLPALPVRPGAQSGQAGQAGQAGRSAPARPARPGAQASQGA
                     PAGFTGQGGGPGAPGGGLSDDTAILTPQRPAQPGTPGYGPRHDNVSGHTVTSGIPVVPP
                     GADFNAPGTPADGPRPHTPPKLPEPVSTPPASSSKPAKKKGRNKLVLLCGCVVLLAGVA
                     YGAGLLMNRSDVPKGTTVLGVDIGGGTRDEAVKKLDAALDDRLNQPLKLSVGGKTVELE
                     PDNAGLQFDTDATVGGAAGSDYNPVNVIGSLIGNERVVEPVMPVDEEKLQAALEAAAGG
                     SGSMVEGSIKFESGKAVPVYPKGGQGIDVAKAADVVAEAYRTQVETGKSATVNVPTTAQ
                     QPKVTKAEVDRMMKEFAEPAMSGIATVQTDAAHSVPLSPENSLWKFLGVQAVDGKLAEK
                     PDLKALEELYGQAFDGVLITRGNGKKTPVTPQDVYGALRLALTSKTDRVAVIDTDPS*"
ORIGIN
        1 atggctgagc cggtcctgga ggtcagcggc ctggtcaagc actatccgct gacgcggggt
       61 gtcgtcttcc gcaagcaggt cggcgccgta cgggcggtcg acggcgtgga cttcacgctc
      121 ggccggggcg agacactggg catcgtcggc gagtccggct gcggcaagtc cacggtcgcg
      181 aggatgctgg tcaacctcga acgcccgacg gccggttcga tccgctacaa gggcgaggac
      241 atcaccaggc tgtcgggcaa ggccctgaag gccgtacgcc gcaacatcca gatggtcttc
      301 caggacccgt acacctccct caacccccgc atgacggtgg gcgacatcgt cggggagccg
      361 tacgacatcc atcccgaggc ggccccgaag ggcgaccggc gcaggagggt ccaggacctg
      421 ctggacgtcg tcggcctcga cccggactac gtcaaccgct atccgcacca gttctccggc
      481 ggccagcgcc agcgcatcgg catcgcacgc ggcctggcgc tgcgtcccga ggtgatcgtc
      541 gccgacgaac cggtctccgc gctggacgtg tcggtgcagg cccaggtcgt caacctgatg
      601 gaccggctgc gagccgagtt cggtctggcg tacgtgttca tcgcgcacga cctgtcgatc
      661 gtccggcacc tctccgaccg ggtcgcggtg atgtacctgg ggcggatcgt ggagaccggc
      721 acggacaccg agatctacga gcaccccacg cacccgtaca cccaggccct gctctccgcc
      781 gtgcccgtac cggacccggc ggcgagggag caccgcgagc ggatcgtcct cagcggggac
      841 gtcccctcgc cggcggacgt cccctccggc tgccgcttcc gcacccgctg ccggaaggcg
      901 cgggagcgct gcgcgcggga ggtgccggcg ctcgcggtgc ccgcgtggtt ccgcacggcc
      961 ggggggccgg cggcacacga ctcggcctgc cacttcgccg aggagaaagt gctggtaccg
     1021 gtggaggggt acggcgacgg gccggggtga catggcgcac cccggcccgt ttacggcacc
     1081 cgcacggccg tacgctgatc agcgtgccgt gtccgtatat cggtaccgct tccgtcaagt
     1141 tgcgtgtgtg ttaacgcggt tcgtccccgt ttgtgagccc cagtgagcgc ttgaggaagc
     1201 cgagctggag ccggagcagg ttctcggcga cctcctcctg cggggtcatg tgggtgacac
     1261 cggacagggg cagcacctcg tgcgggcggc cggccgccag cagcgcggag gagagccgca
     1321 gggagtgggc gaccaccacg ttgtcgtccg cgaggccgtg gatgatcatc atcgggcggt
     1381 gcggtccggc ggcgtcgacc aggcccgcgt cgtcgatcac cgagttgcgg cggtagacct
     1441 ccggctgttc gtccgggtgg ccgatgtagc gctcctggta gtgggtgtcg tacaggcgca
     1501 gatcggtgac cggggcgccc accacggccg cgtggaagac gtcgggccgg cgcagggcgg
     1561 cgagggccgc caggtagccg ccgaaggacc agccccggac ggcgacccgg tccaggtcga
     1621 gcgggaagtc ggcggcgagt gcctggaggg cgtccacctg gtcctggacg acgagggcgg
     1681 cgatgtcgtc ccggacggac ttctcccagg cgggcgagcg gcccggcgtc ccgcgcccgt
     1741 ccgcgacgat caccgcgaac ccctggtcgg cgaaccactg cgaggtcagg tgcgggttgt
     1801 gggcggcgag cacccgctgc ccgtgcggac cgccgtaggg atccatgagc accggcagag
     1861 gactgtcacc ggcgtagtcc cggggcataa gcacggcgca cggaattcgg cgtgcgcccc
     1921 cctgggtcag cgtcacgcgg ggggacatac cggggtcttc ggcgtacgac gggacagtcg
     1981 ccatcggttt cccgtcacgc agcacctgga cccgtgaacc tggccggtcc aggaccgccg
     2041 agacgagtac ggtcacaccc ccggcacgta ccgccgagtg cacaccgggc tcctgcgaga
     2101 cgcgctccac gccgagttcg ttcacccggt agacgtgcac ctcaccgatc tcggggccgg
     2161 ccgcctcctc gcccgccgac gccgagacca gcacgtcgtc gtcggagacg tccaggacgg
     2221 cacggatgtg caactgcgct ccggtgagcg gtcgttcacc gacggcgagt cgtcgcgcac
     2281 ccccctcgtc cgcgatccgg accaactgcc cggaagggct ccagcacggc accccgggga
     2341 aaagttccag ccaaatcgga tcttcgtcgg cgtgcaccat ccgggtcgcc ccggagtccg
     2401 ggtccacggc caggatcagt gcggcgcgct ggtcgcgcgc ctggaccagc agcagcgggg
     2461 cacccgccgc tgaccagtgc acatgcgcca gatacgggta gcgcgcccgg tcccaggaga
     2521 cctcggtgcg cgctccgtcg aggtcgatca cgaacagccg gacgtccgcg ttcggggtgc
     2581 ccgccgccgg gtacgccacc cgctgcggct cccgttccgg atgtgccggg tcggagatcc
     2641 accagcgccg taccggcgtg tcgtccacgc gcgccaccag cagccggtcc gactccggag
     2701 cccaccagaa gccccgcgag cggcccatct cctcggccgc gacgaactcg gccagaccgt
     2761 agatgacgtt ctccgactcc ggggtggcga gggcccgttc gtccgtccct tcggccccca
     2821 cgacgcgcag cgcgccccgg gaggcgtagg cgacgtaccg tccgtcgggc gacggacgcg
     2881 ggtcgatcac gggtcccggt acgcgcagtt cgcgtgccgt cccggcccgc agttcggccg
     2941 tgaaaagccg ccctgacaag gcgaaagacg ccaactcgac ggccgcgtcg gtggcgtagc
     3001 cgacgatgcc ggcgccgccc tcacggctcc gctcgcgccg tgcgcgctcc tcgggagaga
     3061 ggttctcgga ggccccgccc aggagggcgc gcgggtcggc cgccacacgt tccccgcccc
     3121 cttccgtgtc gaggacccag agcgaattgg cccggtccgt accggaaccg gagcgcagga
     3181 acacgacacg cgagccgtcg ggagccacgc tgaacgaacg cggcgcgccg agggtgaaac
     3241 ggagggtgcg ggcgtgccgc cgggggaagg agtcggtctc ggtcgtcatg ccctgaccat
     3301 attggccatg cgcccccttg tgcggctgtg cgccgacaga tgcgcacgta cggatagtta
     3361 tgatcgttag cgcatagtgg gtatgaacct gctggctgct gtgtcgcttt acctgccccc
     3421 atgttcctac gtctccctta cccccgcgcc ctgggatctt tggaggtgaa ccgccgtggc
     3481 actctcgatt tcggcggtgg tgctgctggc gatcatcgtc ttcctgctga tcaagaagtc
     3541 gggcctgaag gcagggcacg ccgtggtgtg catgctgctc ggcttctacc tcgcctcgtc
     3601 gacgatcgcc ccgaccatca gcgagctgac gacgaacatc gcggggatga tcggcagcat
     3661 caacttctga gcgaccgttc cgtcttccgg ccgggtcccg aggcacgtcc cgggacccag
     3721 ccggagtcca cgtcccaccc gttcctccgg catgcccgtt tcggtcctgt cttccggccg
     3781 ggttccgagg tgtgtcgcgg gagccggcgg gggggcgtgt cctgcccgct ctttcggcgt
     3841 gcccgtttcc gtcctgcctt ccgccgggcc ccgaggcgcg ttctggggtg cggctggagt
     3901 cccgtcccgg actccgtggg cggttggggc ggggcctctc gggggacggt ggaccggccg
     3961 actcgtgctt gacggcccct cgcctgttac tcgcgggtag ggaatgatgg cgggcactca
     4021 tccacgcgtt caggggcgga gccgacggtg acgacttccg aagaacagag cgaggcgcgg
     4081 accagggtgc acgtcttccg ggacgacgcc ctcggcgacc acgacgcggt cggcctcgcc
     4141 cgcgcgatcc gccggcgcga ggtcggcgcc gccgaggcgg cccgggacgc ggcggcccgg
     4201 gtcaaggccg tagagccccg gctcaacgcg gtccagacgc acctcgacgt cccggcacac
     4261 ggctccgact ccggtggcct cctggccggg gtgccgacct tcgtgaagga caacaccgac
     4321 taccagggac tgccgacggg ccatggaagc gccgcgttcg caccccgcgc cgcccggcgg
     4381 cacgccccgt tcgtccgcca gttcctgagc accggcgtca cggtgctcgg caagacccgg
     4441 ctgcccgagt tcggcttcag ccccaccacg gagtacgagg acgccgagcc cgtccgcaac
     4501 ccgtggcaca cgggccgttc ggcgggcggc tcgtccggcg gcagcgcggc gctcgtcgcc
     4561 gccggagcgg tcccgatcgc gcacgccaac gacggcggcg gatcgatccg catccccgcc
     4621 gcctgctgcg gcctggtcgg cctgaagccc acccgcggcc ggatggtggc gaacgagcag
     4681 ggccgccgac tgcccgtcga cctcgtcgtc gacggcgtcg tgagccgctc ggtgcgcgac
     4741 agcgcggcgt tcctggccgc cgcggagaag cactggcgca acccgaagct gccgcccgtc
     4801 ggcctcgtcg agggcccctc ggagcgccgc ctgcgcatcg gattcctgct ggactccccg
     4861 aacggtgtcc gctccgacgc ggacacccgg gcggcggtga cggagacggc cgagcgcctg
     4921 gaacggctcg gccacaccgt ggaaccggtg gaactctcca tcgacccgca cttcacggac
     4981 gacttcctca cgtactgggg cctgctgtcg ttcctgatcg gcgtcaccgg cagaacgctg
     5041 ggcgcggact tcgaccgccg ccgcatggac gggctgagcc ggggcctgcg cgagacgtac
     5101 gtgagggcct ggcggaccac gccggccgta ctgcgccggc tgaagcgcac acgtgaggcg
     5161 tacgcggcgg ggttccgcgg cctcgacctg atcctctccc cggtcctggc ccacaccacc
     5221 ccgccgatag gccacttgag cccgaccgtc ccgtacgcca cgctgatcga acggctcctg
     5281 aactacgtgg cgttcacccc ggtcgacaac gtcgtcggca caccgtcgct ctcactgccg
     5341 tccgcgagca cgacaccgga cggactgccc atcggcgtca tgttctccgc ccgcccgggc
     5401 gccgaacgca cgctgctgga gctggcgttc gccctggagg cggaccggcc gttccggcga
     5461 ctccgggacg tctgaggggg tgccctctgt ctttgggcaa gccatctcag gggctgacac
     5521 gtcaagcgtc gcctgatggg cttgtggatc acgaggtgaa cccgtcgtac ccctgtgatc
     5581 ccggctcgcc cggaagacgg gtgatgcgaa cgcggccgac tcgtcgtacg ccccgggtga
     5641 ccggcagcat gacggcccgt gcccttggcc gcaggccgcc ggtcccgctt caggcacagc
     5701 gcgcgaagag cgcctgaagg tattcctcca gccgcctggt cagcagggtg ggggtcagat
     5761 cggcacggcc cacctctcgc catgggacgg cgaccttctc cgcctccgga gcgaaggcca
     5821 aggcgtccag caggcgccag tagagatgag aagcggaatc ctcggccagc gtccctcccg
     5881 ccgcgacata gaggtccgcg aaccgcatgc ccgcggaaac cccgtgcagc agggcgaggg
     5941 ccgtcgagca atgggctacg tccaggtctg ccggccccca cgaggtctcc acccagtcga
     6001 cgacgccgct gacccgcagc ccgtcgccgt cgcctgtgaa gaggacattg ccgggatgga
     6061 agtcccggtg caggaaacag gcccggtggg ccgggggctc gcggcggatc acgtccacgg
     6121 cccattgcca cagctcaggc cgctcggtgt cttcgggcag gctcacccgc tcggaagagg
     6181 tccacgcctg atacgcgcgc ggtcgtgtct ccgcggtcac cgacacctgg tggatacgca
     6241 gcagttggcg ggccagtagt tcggcacgcc ggtcggcccc cttgtcgctc aggcgcacgg
     6301 tcccgggcaa cagggacatc agcaaggagg ggtgatcgca gtactgcgct gtcgcgtcca
     6361 cggccaccag cgcggccgcg ggtacatccg tgccgccgag cagacgcaga acggctgcct
     6421 cgcggttcag caggccctcc gcgtgccgga cgaagaaggg cttgacgaag gaccgcagga
     6481 ccagcgcgcg tcgacctgcc ggcccacaga cgtccagacg gcgcatctcc gacgtccaac
     6541 cgccgcgcaa ccgcacggca tcctcgatgt gctccgcctc ggtgagtccc ttctccaccc
     6601 aggcacgcgt cgcatcccag ccgtccgcaa ccatggcggc aggctgatca gttcgcccga
     6661 cggatgcctt cggccacccc actgcggagc catggaaaag acacctcaag cgcataagag
     6721 ccaggatcgg ggccggtgtt ctgccggggc tgcccgtgtc gagtgcgtca ggtgctcgga
     6781 gtgctgaccg ggtccaatcg gggtggaaga ccggttcggt ccttgcgaag cgggccggag
     6841 gtcaatccca gcagccctgc gccgacgagc atggtggcgc aggcggcagt cacgactgtc
     6901 ggaccttcga ggtctgcgag tgtgccgagg aggttgttca tgagcagcag agcgagactc
     6961 tggacgagta cgagtacggc ctgcacacga gacaggtggc tttcaggagt cgctgtgagg
     7021 atcagcggcg cgatgtgggc ggagaacatc ccgttcccga tgccgatcac cagggaagcg
     7081 gccgtcgctt ccgccacgcc gggcgcgagt gcgagtgcga gtactcccag cccggcaagc
     7141 accagcgcgc ttgccgacag gagccccggc cggcccatcg gtccacgctt cacgacaacc
     7201 gcggtgaccg ccaccatgcc gactccttgc gctcctatcg cgagcccggt ggctcccgcg
     7261 ccccactgct cctggcgtgc gagaaggggg aggagcaagg ggagtacagg gagcagaaag
     7321 ccggctgcgg ctccggtgag gcacagcccc ggtcgcagca cgggatggga gaacgccacg
     7381 cgcacaccgt ccatcgcgtc cttgaggaga ctggacgccc ttgtgggcgg cacgtggtgg
     7441 cgtggccgga cgacgacgag cacggtgagg gtgagggcga aggtgacggc gttgaccaga
     7501 gcagcgcctg ccagtccggc gaggccgacg agtacgccgc cgagcggacc gcctcccatg
     7561 ttgacgacct ggccgccgat ctgccggaga gacagtgcgc gggggagctg ctccttctcc
     7621 accaagcggc gaggcatgga tccggaggcc ggcaggtaga aggcgtcgac gacaccgacg
     7681 gctatacccg ctgtgatgag caggacgggc ggggctccca ggtggtaggc gaccgcggcc
     7741 aggacgagag agaaggccag catcgccgcg tcacccgcga tcagtacgcg gcgcgcgctg
     7801 aatcgatcgc tgaccgcgcc accgaggagc aggagaagga cgcggggaag cgtgatggcg
     7861 ctcagagtca gtcctgcgac cgtgccgccg tgctcgctgg cggcccagcc gagggcgaag
     7921 tagaaaaccg agttgcctgc cagggacacc aggatcccgg ccagccacag catgtaggag
     7981 cggggtaacc ggcccttgtc ccgcggctcg ccaggtgctt ggcgcgaggc gactgcgtgg
     8041 gtcgtggtgg agggtttcga gaggctctcg tcaggagctg acaccgagca cccccgactt
     8101 ggtccgaccg gggattgaga tcacggaccg tacggtctca gacggcactg acactgggac
     8161 tgtcgcgtgt gtggcgcagc gctactgggc gggccgactt ccgcttgtac cgccgtgagg
     8221 tcagctgtcg accccatgac ctcacgatct cgtgtcaggt gttctggtgc tccagccgta
     8281 gatcgtgagt ttgctggtgg ggagaggggc gtcggtcagc gacggccgtt actccagcca
     8341 cgtcccgtcg cgcatgatca ctctgccgcg tagttccggt tcgccgcgcc aagcgcgcac
     8401 gctcctcggc accacacgca cgtacagaaa ggaaccttcc tccgtacgcg ggtcccaccc
     8461 gaacttggcg gcgaacgcct cggccgcgtc ttcgggcacg tcctggtccg agaagcattc
     8521 cgcctcaccc tggagaagca ccacgtcgag ggtgtccggc agcgccaggc gcacgcgcgg
     8581 ctcctcgcgg acgttccgcg cggtcgcggt agtggcactg gtgcacaccc acaccgctcg
     8641 cccgtcccac aggaaccaca gcggcacctg gtgcggcccg tgatcgggat gtgctgtcga
     8701 cacccataca tcccgttcgg tggcgagccg ttccagagtg tcgcgcctac gctccgccgc
     8761 ctggcggcgg acgatccccg tggtctgcat gggtgccgac cttaaccagc aggctcagga
     8821 cacgcatgag gcgagggacc tacgcccggc gactgatgaa cctctcagcc tccgttccgg
     8881 aacggccggt acaggtcgac gacgaaaacc gtgagcatct tggcccttac tgtcttcagc
     8941 ctgctcgttt gagcgtctgg atgacgttgc tctgcccact gctcacgctt tcggcgaagt
     9001 ggggcttctc cggcggcggg gcgtcacggc aaggtgacgc cgaccgggga ccttcggcct
     9061 gttccgcgtc cccggccaag ctccgtaagc ggcccgctgg atcagccctc gaccgcgtac
     9121 ggcaggaaac cggcccacgc ggcgggggcg aaggccagcc gggggccttc gacgttcttc
     9181 gagtcgcgga cgtggacggt gccgggctca gccgcgatct ccacgcacga gtcgccctca
     9241 ctgccgctgc tgtagctgct ctcgctcctc gccatcgggc tcggcgtaca cctccagtcg
     9301 ctgcccgagg gctcctcggg cgacatcaag agcctcagcg cccggttccc cgagggggcc
     9361 acccgtatcg ccgccaccct gcgcgagctg gagctccacg gctacctgcg ccgcgaatgc
     9421 gtccgcacct ccaccggccg cctcgtgacc cgcacgatct cgtgcaacca gccgaccgcg
     9481 gcccgcccgc accccgaggc cccctcccgg gccgtcgacc ggccgggacc ctcggcagcg
     9541 gcggaaccac agccgcaccc gcacccgcag gagccctgcg aagagcgcgc accacagcag
     9601 acgcgtgagc ggcgtgcacc gcaggaggcc tgtgaagagc gcggaccgca ggagacgagg
     9661 gagcggcgtg caccgcagga ggcctgtgaa gagcgcggac cgcaggagac gagggagcgg
     9721 cgcgcaccgc aggaggtctg cgaagggcgc ggaccgcagg agacacgtga gcggcgcgcg
     9781 ccccgcaaac ctctccccgc cgtaccgcgc cccgcgtgca acgtccccgc gctgttccgg
     9841 gccgccaccg atctcctcgc ggacctccac cgccacgagc cccggctgct cctctccacc
     9901 ggtgacgcgg cccacctggc ccccggcgtc gccgcctggc tggagcggga cgtcaccccc
     9961 gccgccgtac gccgcgcgct gaccgccgac ctgccgcctg agggcgtacg ccgtcccgcc
    10021 gccttcctgg cccaccgcct cgccgcccag ctcccgcccc cgcccccgtt ccgtgcgtcg
    10081 gccgccccgc cggccgtacg gcaccccctg cagaactgcg acggctgcga ccgcgccttc
    10141 cgcgcacccc accccggccg ctgccgcgcc tgccggaccg gcctccagga ggccgcctag
    10201 catgaacgtg acgatccttg cccctgggca cagacgacga ggagcgggcg ccatgaccat
    10261 cgcatccgac gacatgcgac ggagcgcctc ccaagggacg tgctcagggc cgggtgatcg
    10321 attccgaggg ggacgcccgg agggtcaggg tttcgggacg gtcaccccgc gggccgtgag
    10381 ttcggccacg agggggtggg gcgggtcctg acgggtacgg agactcatcc gcaagggcac
    10441 cctggcggtc ttcagggacg gcagttcgaa cagggcggtg cagtcctcga gggcgtagca
    10501 gtgggagagg tcgatcctga cgaggccggg catgccggtc acggcgccga tgtcctccag
    10561 ctcggtcaga tgggcgacgt ccagggtgcg gagctgcttc tggcccgcca ggcgggagag
    10621 gtccttccag gacatgtgac ccaccgcgag cttctcgaag ggcccggcgg ggatgtccgt
    10681 cacccgtgag cactccgaga ggtacagggt ccgcagcccc tcgcacgtgc ccagggcgcg
    10741 cagcgacttc agggccggca gccggcggag gaccacctcg gacgccgggg agccggccag
    10801 gccgtcgacg ttcccgaggg cgtggcattc gtccacgtac agcttgtcca gtgacgggag
    10861 gccgccgagg tggtcgaggt cggtcaggga ggggcagttc tcgatgcgca gcttgcacag
    10921 tgcgggcagg ccgccgaggt caccggggga gcgcagcagg cggcacccgc tgacctgcaa
    10981 ctcggtcagg cgggggaggc tgcccagagc ctccagactg tgcagccggt tgcacccgac
    11041 gacgtacagg cgttcgaggc ggggcagggt ggcgagggcg gagaagtccc tcagcgcggc
    11101 gcagtcctcg aggctcaccg acaccagggt ggcgagttcc ttggcgtcct cgagagacgt
    11161 gatccgctcg cacccgcgga tcgtcagtga actcatccgc gtcaggtggg acaccgcgct
    11221 cacgtcggtc agttcggggc agccctcgat gcggaccctc tggaggtggg ggtgcgcgcc
    11281 gagtccgtcg accgtcctca gccgggggca gtcctcgatc accaggcggc tgagggcggt
    11341 cagcgcgtcg atgccccgca gactgcgcag ttggccgcag ttgcgcaggt ccagctcggt
    11401 gaccgcgggg acgtcgtgca gcccggccag gtcacggatg ccggtccagc cgaggtcgag
    11461 gacggtgagc cgggtcagcc cggacaactg ccgtgtgtcc ttgaaggacc ggcagccgcg
    11521 gagtgtcagc ttctccagaa cggggaacgc cgcgtcgaac ccctgagtgg aacgcaccct
    11581 ggtcatgctc aggtccagct cacgcagccg gctcagcgtc agcagcggtg tgacgtcctc
    11641 cacggtccgg caccggcgca ggccgagccg ggtcagtgcg gtgaggcggc ccaggggtgc
    11701 gaggtcctcg acgcccgtgc agccgttcag gtcgagaccg gtcagtccgg tgagggcgcc
    11761 gagttcggtg aggtccgtca cctccttgca gcggtcgatc tccagcgtgc ggagcgtggt
    11821 gaggtggcgc aggccccgga gcgacgtcat gcggcgcagc cgcagcccgg tccgttcctc
    11881 ctgggcgaag gccggggcga gcagatgctc gcagaagccg tccgggtcgg cggccgtcgg
    11941 ccataaccgc agcagcgcgt cggagctgta cgcggcggtc ggtgtgaacc gggcggccag
    12001 ttcgagcgcc tccccgccgt cgctgatcaa gacgagttcc cggatggcct tgcgggcgcc
    12061 ggcctgcttc gcaaggccca agtggctgcg atattcgtcg agttgtgcgg tggatccgtg
    12121 ggtgtccgag gtcatggggc ggacagtagg ggaggaaggt gaccacgccg tgtccgcggc
    12181 ccgcccgacg ggaggggcgg aacagaatga cgggcgtccg gggtgcgggc gtggagggcc
    12241 ccgcgcctca tagggtggaa cccatgacgg aactccccga ccggcgtctg ctgctggtgc
    12301 acgcccaccc ggacgacgag tcgatcaaca acggcgcgac catggcgcgg tacgccgccg
    12361 agggcgccca tgtgacgctg gtcacctgca cgctcggtga gcggggcgag gtcatcccgc
    12421 ccggactgag gcacctgagc ggggccgccc tcggcggaca ccggctcggg gagctgaagg
    12481 acgcgatgcg ggcgctgggg gtcgaggacg tccggctgct cggcggggcc gggcggtact
    12541 gcgactccgg gatgatgggg ctccccgaca acgacgaccc cggctgcttc tggcaggccg
    12601 acgtcgaccg ggcggcgggg ctgctcgccg aggtgatcct cgagatccgc ccccaggtcc
    12661 tcgtcaccta cgacgacgac ggcggttacg gccaccccga ccacatccag gcccaccgcg
    12721 tcgccatgcg cgccgtcgag ctcgccgccg acggagggtg ggacatcccc aaggtctact
    12781 ggaaccgggt gccccgctcc gtcgccgagc aggccttcgc ccgcctcgac ggcgacctgc
    12841 ccggcctgcc cttcgagaag gcggccgccg tcggcgacgt accgggtgtc gtcgacgacg
    12901 agcagatcac caccgcgatc gacggcaccg cgtacgccgc cgccaaggcc gctgcgatgc
    12961 gcgcccacgc cacccagatc accgtggccg aaccgtactt cgtgctctcc aacgaactcg
    13021 cccagccgct cttcaccacc gagtactacg agctggtgcg cggcgggcgt cccggagagc
    13081 gggagggcga cctgttcgcc gggatcgggg aggcgccgtg agcgaccggt cgccctccgt
    13141 gctcgcccag ccgctgcgac cgccctccgc ggggcgggtc gtcgcctgcc tggggctgtt
    13201 cctgctcggc gccgtggtcg gtacggccgg ggcgctggtg cagcccgcgt ggttccccgg
    13261 cgggctgctg ctcgccctcg ccgccgaggc ggggctggtc ctgggggcca cccgcgcgct
    13321 ccgcagccgg gccgggggcg gctgggccgc cggcggctgg accctcgtcg tcatcctgct
    13381 caccaccagc cgcccggaag gcgacttcct gttcgccgcg ggcggcggct cctatctctt
    13441 cctcctcggc ggcatcgccg tggctgtgat ctgcgccacc ctcttctccg gacggcaacc
    13501 ggacggccct cccgcccgac ttggcaagtg acgtaccact tcgccacgtc acgggcgtgc
    13561 gggtccggtg tgggtttccc cggcggtact gggatacggg ccggacaggg ccagtaaggt
    13621 ggtgcgcgcc gccgagcctc cctcgaaccc tcggcttcgc ccgagctggg aggactccca
    13681 ccgtgaggtc gtgacgggcg gcggagccaa ccgggagaac ctgccttgag tcgtgaaact
    13741 gacactccgt cctccgggcc cgacgggcgc ggcggagccg cctacccgtc gggcacgccg
    13801 ccctacggga ttccggcgat tccggacgcg ggtacggacg cgggccgttc ggccgcgcgg
    13861 ccggaggaac gcaagaccga gaccacgctg accacgcggg tccgcatcaa catccccgga
    13921 tcgcggccca ttccgccggt cgtcgtccgc aagcccgtcg cggacgcgga gggcaagagc
    13981 ggcaccaccg acgccgaggc ggcggcgccg tccccggctc cggccgccga cgtggccgag
    14041 tctcccgccc agcccgcaca gcccgacggg tccgaccggc cggcggccga ggagaagccg
    14101 gccagcgact ggttcgcgcc gcgcaagtcg ggcgggggca agggcggtcc ggccggcggc
    14161 tccgccaacg gcgcgggcgc gccgagcggt tcgggccccg ccgcgggcgg cgccccgaag
    14221 gccccttccg cgcccggtgg cgcgcggccg ggcggcggcg tcggctccac gggcgcgccg
    14281 ggcggttccc ttcccggcgg cacgcggggc tccggaccca ccggcgcgac cggtgcgacc
    14341 ggcggacccg tggcccccgg gcacggtggc ggcaccggct ccttcgacgt gaccgaggca
    14401 ctggccgccg ggcccgcggg ccccggcacc cgtccgggga cggggcacgg cgacgagccg
    14461 cgccgcgacg acctgccgtt cttcgcggac gaggcgcccc ggcccggccg gcgcggcccg
    14521 cagggcccca cgggcccgac caccgggccg gcgaccggct cgagtccggt cgcccgccag
    14581 acgggcaagg gctccggcgc tcccgccgtc cccggcggtt cgggcctccc cgccctcccg
    14641 gtccgccccg gtgcccagtc cggtcaggcg ggtcaggcgg gtcaggcggg ccggagtgcc
    14701 cccgcacgcc cggcacgccc cggcgcccag gcgtcccagg gcgcccccgc cggcttcacc
    14761 ggccagggcg gcggccccgg cgcccccggc ggcggtctga gcgacgacac cgcgatcctc
    14821 accccgcagc ggcccgccca gcccggcacc ccgggctacg gcccccgcca cgacaacgtc
    14881 tccgggcaca ccgtcaccag cggcatcccg gtcgtcccgc cgggcgcgga cttcaacgcc
    14941 cccggcaccc cggccgacgg cccgcggccg cacacgcccc cgaagctgcc cgagccggtc
    15001 tccacgcccc cggcgagctc ctcgaagccg gcgaagaaga aggggcgcaa caagctcgtc
    15061 ctgctctgcg gctgcgtggt cctcctcgcc ggtgtcgcct acggcgccgg actgctgatg
    15121 aaccgctccg acgtcccgaa gggcaccacc gtgctcggcg tcgacatcgg cggcggcacc
    15181 cgcgacgagg ccgtgaagaa gctcgacgcg gccctcgacg accggctgaa ccagccgctg
    15241 aagctgtcgg tcggtggtaa gaccgtcgag ctggagccgg acaacgcggg cctgcagttc
    15301 gacaccgacg ccaccgtcgg cggggccgcg ggcagcgact acaacccggt caacgtgatc
    15361 ggctccctca tcggcaacga acgcgtcgtc gagccggtca tgcccgtcga cgaggagaag
    15421 ctgcaggccg ccctggaggc cgccgcgggc ggctccggct cgatggtcga gggctcgatc
    15481 aagttcgagt ccggcaaggc cgtcccggtg taccccaagg gcggccaggg catcgacgtc
    15541 gccaaggcgg ccgacgtggt ggcggaggcg taccgcaccc aggtcgagac cgggaagtcc
    15601 gccacggtga acgtcccgac gaccgcccag cagccgaagg tcaccaaggc cgaggtcgac
    15661 cggatgatga aggagttcgc cgagccggcg atgtcgggca tcgcgaccgt gcagaccgac
    15721 gcggcgcact cggtcccgct gagccccgag aactcgctgt ggaagttcct cggggtccag
    15781 gccgtcgacg gcaagctggc ggagaagccc gacctgaagg ccctggagga gctgtacggc
    15841 caggcgttcg acggggtcct catcacccgg ggcaacggca agaagacgcc ggtcaccccc
    15901 caggacgtct acggcgccct gcgcctggcg ctgaccagca agaccgaccg cgtcgccgtc
    15961 atcgacacgg acccgagctg a
//
