LOCUS       reptomyces_RBGC_155308 17187 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_155308
VERSION     Streptomyces_RBGC_155308
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000317595.1
  ORGANISM  GCF_000317595.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1260
                     /protein_domains="PF04261"
                     /protein_domains="TIGR01412"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438372"
                     /pseudo=False
                     /translation="MTTGESATSRTPSRRALIGWGGAGLALGAAAAGGAVAAARGGDDT
                     DPAASGGPVAFHGAHQAGIATPVQDRLHFAAFDVETEDRAEFVTMLKDWTAAARRMTAG
                     KTVGEGAYGGLAEAPPDDTGEALGLKPSRLTLTIGFGPSLFERFGLAEQRPEALVDLPQ
                     FAGDNLDKARSGGDLCVQACADDPQVAVHAIRNLARIGFGKVSVRWSQLGFGKTSSTTP
                     EAQTPRNLMGFKDGTRNIAGTETDRLKKFVWVGEKDGPAWMVGGSYLVARRIRMHIEPW
                     DRTSLQEQEDIFGRDKGEGAPVGKAKERDEPFLKAMKPDAHVRLAHPDSNHGATILRRG
                     YSFTDGTDGLGRLDAGLFFLAYQRDVRKGFIPIQRNLATDALNEYIQHVGSAVFAIPPG
                     VRDANDWWGRALFETPSKGA*"
     CDS             1266..2140
                     /protein_domains="PF03239"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438373"
                     /pseudo=False
                     /translation="VFANYLIGLREGLEASLVVCILIAYLVKTDHRQALKPIWIGIGVA
                     VGLALGFGCVLEFGSQELTFQAQEALGGSLSIIAVGLVTWMVFWMRRAARHLKAELHGK
                     LDTALRMGTGALVATAFLAVGREGLETSLFVWTSVHASSDGTEAPLIGALLGLATAVVL
                     GWLFYRGALRINLAKFFTWTGGMLVVVAAGVLAYGFHDLQEADFLPGLKDKAFDITDTI
                     PPDSWYGTLLKGVFNFQPDPTVLQVTVWLLYLIPTLALFLAPVGFASGKGKVKFPDEQG
                     SRGSEPTKAS*"
     CDS             2224..3128
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438374"
                     /pseudo=False
                     /translation="VVVRGDLEIVPTATRAEATRALEEFTTAYNAADKANDQSLDANRV
                     TGALADIDGGKLRSGARINPTGNPDHVPLKLTDVRYTIPEKAAWPRWFMADATANKGRS
                     TDRWLFVFTRDGLDDLWEVSFLTIVAADEMPEFQKDADGYAQVVAPDDTALSIAPEELP
                     EKYGTYLAQDSAVFADGPYTSQERTQRQQNAKRPGIVRQYIDEGLTNGDYAPVGLRTED
                     GGALVFFTMRHYEKQTAAQGVDIPVNDEAVKALMTGEPKESLTLEFVSNQAVLDPAKTA
                     SDQQVKFLSQVGGLTGARGE*"
     CDS             complement(3185..3936)
                     /protein_domains="PF09250"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438375"
                     /pseudo=False
                     /translation="MSATFGGRTGRQGRISEWLRARRPGRPLQETADVADREALLLASA
                     AAGLPLAPAAYPSGYRCSCDRVGCPTPARHPVSFAWQTQSTTDRAQIEGWARHQPQANF
                     ITATGMVHDVLDVPLAAGREALERLLASGIEVGPVAEEESESGEGRLLFFTLTRGTPED
                     EDEWWPCELDCHPETMDEHPGLRWHCRGSYVLVPPAQLPGDLAVHWVRGPEHPLPDPLS
                     LLEILTDACARHANEEPDHTNAAWPLRG*"
     CDS             complement(4315..4943)
                     /protein_domains="PF16859"
                     /protein_domains="PF00440"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438376"
                     /pseudo=False
                     /translation="MAKKTAPDSARRSEKSRRAIYDAALALIGEVGYQKTTIEGIAARA
                     GVGKQTIYRWWSSKAEVLLEAFLDLQDQAAEAAAGPGLEPEEYAIPDTGDLAADLKYVL
                     RATVDELLDPKFEAPFRALAAAGLVDEKLSGEFVERLLEPQLQFYVRRLRSAQDSGQMR
                     PDLDPRIALELFVAPLAQRWLQRSGPITYEYTDTLVDYALHGLAPR*"
     CDS             5339..5553
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MSAADRPLRGRAHNDPGGLAPKGEDTVGPGIKREPTPAASCGSGT
                     WKPRWSPGVDPGKPEVTKDQASSGTG"
     CDS             5731..7514
                     /protein_domains="PF00078"
                     /protein_domains="PF13655"
                     /protein_domains="PF08388"
                     /protein_domains="PF01844"
                     /protein_domains="TIGR04416"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438377"
                     /pseudo=False
                     /translation="MPKVGVAVAATVAMPPTTANGPEDYAQTWHSIDWAKAEASVRRLR
                     QRIFTAAQEGDLKKVRNLQKLMLRSHSNTLVSVKRVTQQSTGRRTAGIDQERALTPSAR
                     GRLAAEITAERSPGKPLPVQRVYIPKANGKQRPLGIPVIRDRVRQARVKNALEPEWEAR
                     FEQRSYGFRPGRGCHDAIGAIFNIAGQKRAKRLWVLDADLTAAFDRISHDHLMSLIGTF
                     PAREAIRGWLKAGVMDCGRFSPTDEGTPQGGVISPLLLNVALHGMETAAGHLTEGRSHK
                     SRRDAPVLVRYADDFAVFCHSEDEAHQVKEQLAVWMAPCGVAFNEEKTSVLHLEEGFDF
                     LGFNIRRYSGTLLIKPSKAAVKRVRERLRSEVIGLRGANAGAVVRRLNPIIKGWATYYR
                     TVVSKETFKSLDFYVWTLTQKWVKHSHPNKPKSWRLAKHYGVFNSTRKDQWVFGDRDTG
                     TYLYKFNWTRIVRHVIVKEGNSPDDPSLAEYWASRRRKRVPGTADRWTITLASRQKGIC
                     PLCKQPLIPDAEYTPDNPREWAAWFSASMKPLHKHHFIYRRDGGTDERTNLRLVHADCH
                     RQHHAGDHRRAKQDDRPA*"
     CDS             7631..7842
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438378"
                     /pseudo=False
                     /translation="MLGVGGTRSNLSRKALRGGKGKGRIGGELDPQAQKRELLRKLQEK
                     RQQEAPPQERQQGRSSAGGTAGETS*"
     CDS             8131..10106
                     /protein_domains="PF13520"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438379"
                     /pseudo=False
                     /translation="VSISLKRLIVGRPLSSDRLGEQRLPKRIALPVFASDPLSSVAYAT
                     QEILLVLTLGGLAYLHLAPWVAAAVVVLLAVVVLSYRQVVQAYPSGGGSYEVASRNLGP
                     SAGLVVASALMVDYVMTVAVSVAAGVDNIISAVPALGPYRVAVNLGFVVLLTAMNLRGV
                     RESGRLFAVPTYLFIAGVLAMVAIGLLQTAFGHAPVAESAEWQVHAEPGGTGLTGMALV
                     LLALRAFSSGCTALTGAEAISNGVPAFRPPKARNAATTMAVMGGLSISMFAGITALALI
                     ADVRYVEDACQLVGFPGDCATGSQRTVIAQIAAAVFGGTDTVMFFYIQAATALILILAA
                     NTAFNGFPLLAAILAEHRYLPRQLHTRGDRLAFSNGIVILAVVAGILIHAFEGSVTRLI
                     QLYILGVFTSFTLSQAGMVRHWNRELAGRTDPAQRRRVHRSRVINAMGACLTALVLVVV
                     LVTKFSHGAYLVVIAMPVLYAMMRGIRRHYDRVARELRPKPGGIVLPSRIHAVVLVSQL
                     HQPTLRALGYAKATRPDTLTALTAKISDEEVSALRAEWEERRIPVPLTVMASPYRDITG
                     SVLEYIAGLHHEHPQDLIAVYIPEYVVGHWWEQLLHNQSALRLKARLLFQRGVMVTSVP
                     WQLDSSDRMQPHEDPRGAESTVG*"
     CDS             10119..11530
                     /protein_domains="PF13493"
                     /protein_domains="PF02518"
                     /protein_domains="PF00512"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438380"
                     /pseudo=False
                     /translation="MKGLDLQHPGGRRRRSTGRRLAAAGAAAAGLAVLTAALVPLRDSL
                     SLASVVLIYLTAVVIVAATGGLPMALAAAVASDVLVNFFFVPPFHTLTVEDRDLFITLA
                     VYVAVATTVSVAVDLAARQRAAAARSGVEAALLARITQAPLEERPLSAVLEHVRDTFGM
                     TGAALLERDADGERPVAVVGEPPSADPTLSAPAGEDLRLVADGPAVFAADERFLTLLAT
                     AAARALQAERLAAQAARARELTEIDKLRAALLAAVGHDLRTPLAGIKACVSSLREPDLE
                     LTDAQQAELLATVDASADKMSDLVENLLALSRLQAGALSVHPRPTALDEITAAALLHTP
                     PAPGRAVDVDVPDDLPPAWADPGLLERVIANLVANALDAGPPDQPVHVHARQEGNMIRL
                     RITDHGPGVPADQRERIFAPFQRLDDHTTRHGLGLGLAIARGFTEAMNGTLTPTDTPGG
                     GLTMTLTFPTAP*"
     CDS             11528..12213
                     /protein_domains="PF00072"
                     /protein_domains="PF00486"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438381"
                     /pseudo=False
                     /translation="MTRILVVDDDPHLLRALTIALTARGYQTNAVPDATTALQAAATHA
                     PDLAVIDLGLPDLDGINIVESLRGWSTAPIIVLSARHDETAKINALDAGADDYVTKPFG
                     MGELLARIRAALRRATPADEQPVITTAAFTVDLAAKRVTTAVGEVRLTPTEWHLLEILV
                     RQPGRLVTQRQLLQEVWGPRYEKETNYLRVHLANLRRKLEPEPSQPRYLITEPGIGYRF
                     TPDTPA*"
     CDS             complement(12248..13302)
                     /protein_domains="PF09243"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438382"
                     /pseudo=False
                     /translation="VNAPLSPSSASPADTLRAALAALLDGLPPKAATQAVERLIAKYRG
                     RTPTDAPVLRDRADVVAYAAYRMPATFEAVCSALEAFAVAVPGWVPGSHVDVGGGTGAA
                     TWAVNATWAGGRPVTVLDWAEPALALGREIAAANPELKAAEWQRSRIGSALRIESTDLV
                     TVSYVLGELTAADRTAVVDAAATAAQAVVIIEPGTPDGYARVIEARDRLIDAGFHIAAP
                     CPHSAACPIVPGEDWCHFSARVSRSSLHRQVKGGSLAYEDEKFSYVAATRFPPTPAPSR
                     VVRKPQIRKGQVLLDLCQGHSQPEPRPESDARPALARTTVTKRHGLLYKAARDAEWGDA
                     WPPPTADDDQG*"
     CDS             13386..13711
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438383"
                     /pseudo=False
                     /translation="MSSASEVKTATRPDRRTTVAHSMASCRAPGTAAAYATRAGAAGSR
                     VGSEIPPLYGRLRCAGAHQLSSSSMRNPRIIDGLLPIGGGDGACGQTGAIGWLMVGDIC
                     CWLP*"
     CDS             complement(13574..14331)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438384"
                     /pseudo=False
                     /translation="VLRDWLPYMNPAIEPFVSSQDISKGERGLAKIANKLQDCMYGIVC
                     VTRDNQHAPWINFESGALSKELGETRLAPFLVDLAVKDLSGPIAQFQATEGSSRDEVWA
                     LVKSLNDKCEMTVEQDRLAVTFERFWGDLEEKLDAIRSEQMPTAVPEREMPEILNELVA
                     LVRDQAKRMSSLEESLAGLQAGNNTSIPGSASASSYGGGGSAPSYGSQQQMSPTMSQPM
                     APVWPQAPSPPPMGKSPSMMRGFLIDEDDN*"
     CDS             complement(14472..15523)
                     /protein_domains="PF00144"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438385"
                     /pseudo=False
                     /translation="VRALTEGDRPSAPAAVVIAGRGPVIAVEEAAGWAVRYEAYDERTD
                     RGVEPPPESWLPATPDTPFDLASLTKLFTAVAAVQQLERGTLGIDAKVGAYLPDFTGAA
                     EHGLTVRQLLTHTSGLRPELPLYDCLTPDARLAMLQAESPIAAPGTAYAYSDLNLLLLQ
                     HLLERLTARRLDVLIRDGITHPLGMTSTVFGPCPTAAATEDQRRPWAKADRGMLRGEVH
                     DENAWSLGGVAGHAGLFSTARDLAVFCRTLLAGGSYGPARILGPDFVELMLTPPGLGFA
                     LDQPWFMGELSGRGAAGHTGFTGTSLVLDPATDTFLILLTNAVHPRRRGPINAARAAAG
                     TRVARAVRGA*"
     CDS             complement(15602..17187)
                     /protein_domains="PF07690"
                     /protein_domains="TIGR00710"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7438386"
                     /pseudo=False
                     /translation="MPEGHIPGSAPAEPKPMAEPMAEPMAEPMAEPMAEPMAESTTAAP
                     EPGLAPGQVTSGTEPSKPSPLSSKPSRRSSRPSRRSSRPSRRSSRPSRRSSRPSPQPSK
                     PSPAALRRTGLLVTLVLGGLTATPPLAMDMYLPALPEVTDSLHAPATTVQLTLTACLAG
                     MALGQLLIGPMSDRWGRRRPLLLGLAVYIVATVLCALAPTVETLIALRLVQGLAGSAGI
                     VIARAVVRDLYDGEAMARFFSTLMLISGVAPIVAPLIGGQILRVTDWRGVFVVLTVIGV
                     ALLAVVWTRLPETLAPADRHSGGIGETLHAMRGLLTDRVFMGYVLAGGFAFAALFAYVS
                     ASPFVIQEIYGASPQTFSLLFGVNSVGLVIAGQINGKVLVGRVSLDKVFAVGLAIVTLS
                     ATALLLMALGAFGEVGLAPVAAALFVLMAAMGIALPNTQTLALMRVRHAAGSASALMGT
                     SSFLIGAVASPLVGVAGEDTAVPMAVVQLAATLVAATCFVALCRPWNRRTTLEDGGTRL
                     SSGAERLGEES*"
ORIGIN
        1 atgaccaccg gggaatccgc cacctcccgt accccgtcgc ggcgtgcgct gatcggctgg
       61 ggcggtgccg ggctcgcgct cggtgccgcc gcggccgggg gcgccgtcgc cgcggcacgc
      121 ggcggcgacg acaccgaccc cgccgcgagc gggggcccgg tcgccttcca cggcgcccat
      181 caggccggta tcgccacccc cgtccaggac cggctgcact tcgccgcgtt cgacgtggag
      241 accgaggacc gcgccgagtt cgtgacgatg ctgaaggact ggacggcggc ggcgcgccgg
      301 atgacggccg ggaagacggt cggcgagggc gcgtacggcg ggctggcgga ggctccgccg
      361 gacgacaccg gcgaggcgct gggtctgaag ccgtcccggc tgacgctgac catcggcttc
      421 gggccgtcgc tgttcgagcg gttcgggctg gccgagcagc ggcccgaggc gctggtggac
      481 ctcccgcagt tcgccggtga caacctcgac aaggcccgca gcggcggcga tctgtgcgta
      541 caggcctgcg cggacgatcc ccaggtcgcg gtgcacgcca tccgcaacct cgcccgcatc
      601 ggcttcggca aggtctcggt ccgctggtcc caactcggct tcggcaagac ctcgtcgacg
      661 actccggagg cccagacccc gcgcaacctc atggggttca aggacggcac ccgcaacatc
      721 gcgggcacgg agacggaccg gctgaagaag ttcgtgtggg tgggcgagaa ggacgggccc
      781 gcctggatgg tgggcggctc gtatctcgtc gcccggcgca tccggatgca catcgagccc
      841 tgggaccgca cctcgctgca ggagcaggag gacatcttcg gccgcgacaa gggcgagggc
      901 gcgccggtgg gcaaggccaa ggagcgcgac gaaccgttcc tgaaggcgat gaagccggac
      961 gcgcacgtac ggctcgcgca ccccgactcc aaccacgggg cgaccatcct gcgccgcggc
     1021 tactccttca ccgacggcac ggacggcctc ggccggctgg acgcgggcct gttcttcctc
     1081 gcgtaccagc gtgatgtccg caaggggttc atccccatcc agcgcaatct ggccacggac
     1141 gcgctcaacg agtacatcca gcacgtgggt tcggcggtct tcgcgatccc gccgggcgtc
     1201 cgggacgcga acgactggtg gggccgggcg ctgttcgaga cgccttcgaa gggggcctag
     1261 ggccgtgttc gcgaactatc tgatcggtct gcgcgaaggc cttgaggcga gcctcgtcgt
     1321 ctgcatcctc atcgcgtatc tggtgaagac ggaccaccgg caggccctga agcccatctg
     1381 gatcggcatc ggtgtcgccg tcgggctcgc cctcggcttc ggctgcgtgc tcgaattcgg
     1441 ttcccaggag ctgacgttcc aggcacagga ggcgctcggc ggctcgctgt cgatcatcgc
     1501 ggtgggcctg gtgacctgga tggtcttctg gatgcggcgc gccgcccggc atctgaaggc
     1561 cgagctgcac ggcaagctgg acaccgccct gcggatgggc acgggcgccc tggtggcgac
     1621 ggcgttcctc gcggtgggcc gggagggcct ggagacctcg ctgttcgtgt ggacgtcggt
     1681 gcacgcgtcg agcgacggca ccgaggcccc gctgatcggc gccctgctgg gcctggcgac
     1741 ggcggtcgtg ctgggctggc tgttctaccg gggtgccctg cgcatcaacc tcgccaagtt
     1801 cttcacctgg accggcggca tgctcgtcgt ggtggcggcg ggcgtcctcg cgtacggatt
     1861 ccacgacctc caggaggccg acttcctgcc cggtctgaag gacaaggcct tcgacatcac
     1921 ggacacgatc ccgccggaca gctggtacgg caccctgctg aagggcgtct tcaacttcca
     1981 gcccgacccg accgtcctcc aagtcacggt ctggctcctg tatctgatcc cgacgctcgc
     2041 gctgttcctc gccccggtag ggttcgcctc cgggaagggg aaggtgaagt ttcctgatga
     2101 gcagggttct cggggttcgg agcctactaa ggcttcgtga ggttcgtccg gttcgtacgc
     2161 gtagtgggct gcttggtctg gccacggcgg tgaccgcgct ggcgttgacg gcgagtggat
     2221 gcgtggtggt ccgcggcgac ttggagatcg tccctacggc gacgcgggcg gaggcgaccc
     2281 gtgcgctgga ggagttcacg accgcgtaca acgcggcgga caaggcgaac gaccagtccc
     2341 tggacgccaa ccgggtcacc ggcgcgctcg ccgacatcga cggcggcaag ctccgctcgg
     2401 gcgccaggat caacccgacc ggcaaccccg accatgtgcc gctgaagctg accgacgtcc
     2461 ggtacacgat cccggagaag gcggcctggc cgcgctggtt catggccgac gccaccgcca
     2521 acaagggccg ctccacggat cgttggctgt tcgtcttcac ccgggacggt ctggacgacc
     2581 tgtgggaggt gtcgttcctg accatcgtcg ccgccgacga gatgcccgag ttccagaagg
     2641 acgccgacgg ctacgcccag gtggtcgcgc ccgacgacac cgcgctgtcc atagcgcccg
     2701 aggagttgcc cgagaagtac gggacgtatc tggcgcagga cagcgccgtc ttcgcggacg
     2761 ggccgtacac ctcgcaggag cgcacgcagc ggcagcagaa cgcgaagcga ccgggcatcg
     2821 tccggcagta catcgacgag ggcctgacca acggcgacta cgcgccggtc ggactgcgca
     2881 ccgaggacgg cggcgcgctg gtcttcttca ccatgcggca ctacgagaag cagacggccg
     2941 cgcagggcgt ggacatcccg gtcaatgacg aggccgtcaa ggcgctgatg acgggtgagc
     3001 cgaaggagtc gctgaccctg gagttcgtgt ccaaccaggc ggtgctggat ccggcgaaga
     3061 cggcgtcgga ccagcaggtg aagttcctca gccaggtggg cgggttgacg ggggcgaggg
     3121 gagagtaggc gctgcggggg cgggcctggt ggctactgaa gcgggccggg accggagtgg
     3181 ggctcagccc cgcaggggcc aggccgcgtt cgtgtggtcc ggctcctcgt tcgcgtggcg
     3241 ggcgcaggcg tcggtgagga tctccaggag gctcagcggg tccggcagcg ggtgctcggg
     3301 gccgcgtacc cagtggacgg cgaggtcacc ggggagttgg gccggcggta cgaggacgta
     3361 cgacccccgg cagtgccaac gcaggcccgg atgctcgtcc atggtctccg gatggcagtc
     3421 cagctcgcag ggccaccact cgtcctcgtc ctcgggcgta ccgcgggtga gggtgaagaa
     3481 gaggagccgt ccctcgccgg actcggactc ctcctccgcg acggggccca cctcgatccc
     3541 ggaggcgagc agccgctcaa gtgcctcccg ccccgcggcg agcggtacgt cgagcacgtc
     3601 gtggaccatg ccggtcgcgg tgatgaagtt ggcctgcggc tggtggcggg cccagccctc
     3661 gatctgggcg cggtcggtgg tggactgggt ctgccacgcg aaggacaccg ggtgccgggc
     3721 gggggtcgga cagccgacgc ggtcacagga acaccggtag cccgaggggt acgcggcggg
     3781 cgcgagcggg agtccggcag cggcggaggc gagcaacagc gcctcgcggt cggcgacgtc
     3841 ggcggtctcc tggagtggac ggcctgggcg acgggcgcgc agccactcgg agatcctgcc
     3901 ctgccggccg gtccggccgc cgaacgtcgc gctcatctat cccctcgcct cgctgttgtg
     3961 cggacagcat gccccatggt cccaccatcc tgcgctccgg gtggccagag cccacatccg
     4021 gggtaggtgc ggccaagccg gagcgcggac agggatggtg ggctattaca cgctttgacg
     4081 gtatttggag tccggctgga gcccaccgcc gagccccact tggtcggatt ggtcacacct
     4141 ggcgtggcgc cggcggcgcg gaaccggtcg cgctcaggga gtcaccggcg gcgagggacc
     4201 ggtcgtgtcc ggggagtcac cggcggcgcg gaaccggtcg cgctcaggga gtcaccggcg
     4261 gcgagggacc ggtcgcgctc agcaagcttc cggccgcgtg ggaccccatc gggtcagcgg
     4321 ggtgcgaggc cgtggagggc gtagtcgacg agggtgtccg tgtactcgta tgtgatgggt
     4381 ccgctgcgct gaagccagcg ctgggccagc ggtgcgacga agagttcgag ggcgatgcgc
     4441 ggatcgaggt ccgggcgcat ctgccccgag tcctgcgcgg accgcaaccg gcggacgtag
     4501 aactggagtt ggggttcgag gagcctttcg acgaactccc cactgagctt ctcgtcgacg
     4561 aggcccgcgg cggcgagggc acggaagggg gcctcgaact tcggatcgag gagttcgtcg
     4621 acggtggccc gcaggacgta cttcaggtcg gccgcgaggt cgccggtgtc cgggatcgcg
     4681 tactcctcgg gctccagccc cggcccggcc gccgcctccg ccgcctggtc ctgcagatcg
     4741 aggaacgcct ccagcaggac ctccgccttc gaggaccacc accggtagat cgtctgcttg
     4801 ccgacgccgg cccgcgccgc gatgccctcg atggtcgtct tctgataccc gacctcaccg
     4861 atgagcgcga gggcggcgtc gtagatggca cggcgggact tctcgctgcg ccgggcggag
     4921 tcgggggcgg ttttcttggc catgcgtcga atttatcagg ttgacaagac gctgcgtctc
     4981 gccagacagt ggttcgcggg ccctcggcga gacgagccgt atcgtcacca cgtccagggc
     5041 cccgcgatca ggacccctat cccgagagga gacctccagt gcgacacgaa gtcgctccac
     5101 ccaagtggat gacttgcagg aggaaagaag gtcatgagca ggtcatcccg gaccagtgtc
     5161 caaggtccgt tcccacttcc gcatgcgtcg ctggcaacgg cggggtgtga agccggaagc
     5221 gtaagcccaa gagcggcacg gccatcgggc cgcaacaggc gaggggaaga ccggacgggc
     5281 taatgcgaat gaacccttga cgaaatctcg taactcctat gccgcgtcga tggtgagctg
     5341 tcggcggcag acaggccctt gcgcggaaga gcgcacaacg accccggagg attggcgccg
     5401 aagggggagg acaccgtcgg gcccgggatt aagagggagc ccaccccggc cgcatcttgt
     5461 gggagtggaa cgtggaaacc ccgttggagt ccgggagttg atcccggtaa gccggaggta
     5521 acgaaggacc aagcctccag cgggacagga tgatccgaga agcgaacgcc gacagggcga
     5581 aagcccagag gaaaaggacg cggagtcctc agccgcaccc aataactcgt cggatacgag
     5641 gcgatgcccg gcccgaaagg gagctcacgc ggatcaggta ggcccgtgaa gaagaactgc
     5701 gaagaacccc gaaccgaagg gcaagttgga tgccgaaggt aggtgtggca gtggccgcta
     5761 cggtggcgat gcctcccacg acggcgaacg gaccggagga ctacgcccag acctggcaca
     5821 gcatcgactg ggccaaggcg gaggcgtcgg tacggcgact gaggcagcgc atcttcacag
     5881 ccgcgcagga aggggacctg aagaaggtcc ggaacttgca gaagctcatg ctgcggtccc
     5941 actcgaacac gctcgtgagc gtgaaacggg tgacgcagca gagcacaggc cgtcggacgg
     6001 ccgggatcga ccaggaacgc gcgctcactc cgagcgcgcg agggcggctg gccgctgaga
     6061 tcacagcgga acgctcgcct ggaaagcccc tgcccgtcca gcgcgtgtac attcccaaag
     6121 ccaacggaaa gcagcgcccc ttgggtattc cagttatccg tgaccgagtc cgccaggccc
     6181 gcgtcaagaa tgcactggaa cccgagtggg aagcccggtt cgagcaacga agctacggtt
     6241 tccgccccgg ccggggctgt catgacgcga tcggcgccat cttcaatatc gcgggccaga
     6301 aacgggccaa gcggttatgg gtgctcgatg ctgatctgac agcggcgttc gaccgtattt
     6361 cgcacgacca cctgatgagc ctcatcggta ctttcccggc gcgggaagcg atccgcggat
     6421 ggctcaaggc gggagtgatg gactgcggac gattctcgcc caccgatgag gggacccctc
     6481 agggtggtgt gatcagtccg ctgctgctca acgtggcctt gcacggcatg gagacggcgg
     6541 ccgggcatct cacagaagga cgttcccaca agtcccgacg agatgctccg gtcctggtcc
     6601 ggtacgcgga tgactttgcg gtgttctgcc acagcgaaga cgaagcgcac caggtcaagg
     6661 agcaactggc tgtctggatg gccccgtgcg gggtcgcctt caacgaggag aagacatccg
     6721 tcctccacct tgaagaagga ttcgacttcc tcgggttcaa catccgcagg tacagcggaa
     6781 ctctgctgat caagccgagc aaggcggctg tgaaaagggt ccgggaacga ctccgcagtg
     6841 aggtgatcgg cctgcgaggg gcgaacgccg gagctgtggt gaggaggctc aacccgatca
     6901 tcaaggggtg ggccacctac taccggacgg tggtgtccaa ggagaccttc aagtccctgg
     6961 acttctacgt gtggacgctc acacagaagt gggtcaagca ctcccacccg aacaagccga
     7021 agagctggcg actggccaag cactacggcg tcttcaactc gacccggaag gaccagtggg
     7081 tattcggtga ccgggacacc ggcacctacc tctacaagtt caactggacc agaatcgtcc
     7141 ggcacgtgat cgtcaaggag ggcaactccc ccgacgatcc ctcgctggcc gaatactggg
     7201 cgagccgccg acgcaaaagg gtgcccggga ccgccgacag gtggaccatc accctcgcat
     7261 cccgccagaa ggggatctgt ccgctgtgca aacagccgtt gatccccgac gccgagtaca
     7321 caccggacaa ccctcgcgag tgggccgcgt ggttctcggc atcgatgaag ccgctgcaca
     7381 agcaccactt catctatcgg cgcgacggcg gcacggacga gcggacgaac cttcgcctcg
     7441 tacacgctga ctgccatcgc cagcaccacg ccggcgatca cagaagggcc aagcaagatg
     7501 accgacccgc gtgactccag gggcccgctt gagccggatg cggtgaacag ccgcacgtcc
     7561 ggttctgagg gggccggggg gcggcaacgc cctccggcta cccgactgag ccgaggcgga
     7621 gccggaaaca tgctgggagt cggcggcacc cgcagcaacc tgagccgcaa ggccctgcgc
     7681 ggcggcaagg gcaagggccg catcggcggc gagctcgacc cgcaggccca gaagcgggaa
     7741 ctgctgcgga agcttcagga gaaacggcag caggaggcgc ccccgcagga acggcagcaa
     7801 ggacgttcga gcgcgggagg cactgccggc gagacgtcgt gaaccggagt ggggctgccc
     7861 cgcccgaggc catcgcaggc ttcgggcggg acagccccgc tgattcagtg ggtggctcga
     7921 tgttcgagtg tccgccggcg ccggccgggt gacacggctg cgccgtcacc gggtactgcc
     7981 gccgggagtc ccgatcgggc ccggtccgag gcggacggcc gggctgtggc cggacggtca
     8041 tgccaagacg gcgtgaagat cgccggtggc ggcgtcaagg acgcgccaag attcgggcac
     8101 cgcttcgatc ggcgcgttgg ctgccggatg tgtcgatatc gctcaagcgg ctgatcgtgg
     8161 gccggccgct cagcagtgac cgtctgggtg agcagaggct gcccaagcgg atcgccctgc
     8221 cggtcttcgc cagtgacccc ttgtcgtcgg tggcgtacgc gacgcaggag atcctgctcg
     8281 tgctgaccct gggcgggctg gcctatctgc atctggcgcc gtgggtggcg gcagcggtgg
     8341 tggtgctgct ggcggtggtg gtgctgtcct accggcaggt ggtgcaggcc tacccctccg
     8401 gcggagggtc ctacgaggtg gcctcccgca acctgggccc ctcggcgggg ctggtggtgg
     8461 cctcggcgct gatggtggac tacgtgatga cggtggccgt gtcggtggcg gccggcgtgg
     8521 acaacatcat ctccgcggtg ccggccctgg gcccgtaccg ggtggcggtg aacctcggct
     8581 tcgtggtgct gctgaccgcg atgaatctgc gcggggtccg cgagtcgggg cggctgttcg
     8641 cggtgccgac ctatctgttc atcgccggcg tgctggccat ggtcgccatc gggctgctgc
     8701 agaccgcctt cgggcacgcg ccggtggccg agagcgccga gtggcaggtg cacgccgagc
     8761 cgggcgggac ggggctgacc gggatggcgt tggtgctgct ggcgctgcgg gcgttctcct
     8821 ccggctgtac ggcgctgacc ggtgcggagg cgatctccaa cggggtgccg gcgttcaggc
     8881 cgcccaaggc gcggaacgcg gcgaccacga tggcggtgat gggcgggctg tcgatcagta
     8941 tgttcgccgg aatcacggca ctggccctga tcgcggatgt gcggtacgtc gaggacgcct
     9001 gccagctggt cggtttcccc ggggactgtg cgaccggctc gcagcgtacg gtgatcgcgc
     9061 agatcgcggc ggcggtgttc ggcggcacgg acacggtgat gttcttctac atccaggccg
     9121 cgaccgcgtt gatcctcatc ctggcggcca acaccgcctt caacggcttc ccgctgctgg
     9181 cggcgatcct ggccgagcac cgctatctgc cccggcagct gcacacccgc ggggaccggc
     9241 tggcgttctc caacggcatc gtcatcctgg ccgtggtcgc cggaatcctg atccatgcct
     9301 tcgaaggatc ggtgacccgt ctgatccagc tctacatcct gggcgtgttc acctccttca
     9361 ccctctccca ggccggcatg gtccggcact ggaaccgtga actggccggc cggaccgacc
     9421 ccgcacagcg tcggcgcgtc caccgctccc gcgtgatcaa cgcgatgggc gcctgcctga
     9481 ccgcgctggt gctggtcgtg gtcctggtca ccaagttcag ccacggcgcc tacctggtgg
     9541 tgatcgccat gccggtgctg tacgcgatga tgcgcggcat tcgccgtcac tacgaccggg
     9601 tggcccgcga gctgcgcccg aagccgggcg gcatcgtgct gcccagccgt atccacgcgg
     9661 tggtgctggt ctcgcagctg caccagccca ccctgcgcgc gctgggctac gccaaggcca
     9721 cccgcccgga caccctcacc gcgctcaccg ccaagatcag cgacgaagag gtgagtgcgc
     9781 tgcgcgccga gtgggaggag cgccggatcc cggtgccgct gacggtgatg gcctccccgt
     9841 accgcgacat caccggctcg gtgctggaat acatcgccgg cctgcaccac gagcaccccc
     9901 aggacctgat cgccgtctac atccccgaat atgtggtcgg ccactggtgg gagcagctgc
     9961 tgcacaacca gtccgcgctg cggctgaagg cacggctgct gttccagcgc ggggtgatgg
    10021 tgaccagcgt gccgtggcag ctggactcca gcgaccgtat gcagccgcac gaagacccgc
    10081 gtggcgccga gtcgaccgtc ggttagcgtt tcgcatcatg aagggcttgg atctgcagca
    10141 ccccggtggc cggcgacgca gaagcacggg ccgtcggctg gccgcggccg gcgccgccgc
    10201 ggcgggcctg gccgtcctca ccgcggccct cgtacccctg cgggactcgc tgtcgctggc
    10261 cagtgtcgtg ctcatctacc tcaccgcggt ggtcatcgtg gccgccaccg gcggcctgcc
    10321 catggcgctg gcggcggcgg tggcctccga tgtgctggtc aacttcttct tcgtcccgcc
    10381 cttccacacc ctgaccgtcg aggaccggga cctgttcatc accctggccg tctacgtggc
    10441 ggtcgccacc accgtcagcg tcgcggtcga cctggccgcc cggcagcgcg ccgccgccgc
    10501 ccgcagcgga gtcgaggccg ccctgctggc ccgcatcacc caggcgccgc tggaggaacg
    10561 gccgctgagc gcggtgctgg agcacgtccg ggacacgttc ggcatgaccg gcgccgcgct
    10621 gctggaacgc gacgccgacg gcgaacgccc ggtcgccgtc gtcggtgagc cgccgtcggc
    10681 cgatccgacg ctgtccgcgc cggccgggga agacctgcgc ctggtggcgg acggcccggc
    10741 cgtcttcgcc gccgacgaac gctttctcac cctgctggcc acggccgccg cccgcgcact
    10801 gcaggccgag cgcctggctg cccaggccgc ccgagcgcgg gaactgaccg agatcgacaa
    10861 actgcgcgcc gccctgctgg ccgccgtcgg ccacgacctg cgcaccccgc tcgccggcat
    10921 caaggcgtgc gtgtccagcc tgcgcgagcc cgacctggaa ctcaccgacg cccagcaggc
    10981 cgaactcctg gccaccgtgg acgcctccgc cgacaagatg agcgacctgg tcgaaaacct
    11041 cctcgcgctc agccgcctgc aagccggcgc cctcagcgtc cacccacggc ccaccgcgct
    11101 ggacgagatc accgcagccg ccctcctgca caccccgccg gcccccggcc gcgccgtcga
    11161 cgtcgacgtc ccggacgacc tgccgcccgc ctgggccgat cccggcctgc tggaacgggt
    11221 catcgccaac ctggtcgcca acgcgctcga cgccgggcca ccggaccagc ccgtccatgt
    11281 gcacgcccgt caggaaggaa acatgatccg cttgcggata accgaccacg gccccggcgt
    11341 ccccgccgac cagcgggaac gtatcttcgc cccgttccag cgcctggacg accacaccac
    11401 ccgtcacggc ctcggcctgg gcctggccat cgcccgcggc ttcaccgaag ccatgaacgg
    11461 caccctcacc cccaccgaca cccccggcgg cggcctgacc atgaccctca ccttccccac
    11521 agcaccatga cccgcatcct cgtcgtcgac gacgaccccc acctgctgcg cgccctgacc
    11581 atcgccctga ccgcccgcgg ctaccagacc aacgccgtcc ccgacgccac caccgccctg
    11641 caggccgccg ccacccacgc ccccgacctg gccgtcatcg acctcggcct gcccgacctc
    11701 gacggcatca acatcgtcga aagcctccgc ggctggtcca ccgccccgat catcgtcctg
    11761 tccgcccgtc acgacgagac cgccaagatc aacgccctgg acgccggcgc cgacgactac
    11821 gtcaccaaac ccttcggcat gggcgaactc ctcgcccgca tccgcgccgc cctacgccgc
    11881 gccacccccg ccgacgaaca gcccgtgatc accacagccg ccttcaccgt cgacctggcc
    11941 gccaagcgcg tcaccaccgc ggtcggcgag gtccgcctca cccccaccga atggcacctg
    12001 ctggagatcc tcgtccgcca gcccggacgc ctggtcaccc aacgccaact cctccaggag
    12061 gtctggggac cgcgctacga gaaggagacc aactacctgc gcgtccacct cgccaacctc
    12121 cgccgcaaac tcgaacccga gccctcccaa ccccgctacc tcatcaccga acccggcatc
    12181 ggctaccgct tcacccccga cacccccgcc tgaccgcgtg gatgaccggc ggttgaacgc
    12241 cgccctctag ccctggtcgt cgtccgcggt cggtggcggc caggcgtcgc cccattccgc
    12301 gtcgcgtgcc gccttgtaga ggaggccgtg gcgcttggtc accgtggtcc gggcgagggc
    12361 gggccgggcg tcggactcgg gccggggctc gggctgggag tggccttggc agaggtccag
    12421 gaggacctgg cccttgcgga tctgcggctt gcgtacgacg cgggaggggg ccggggtcgg
    12481 cgggaagcgg gtggcggcga cgtagctgaa cttctcgtcc tcgtacgcca gggagccgcc
    12541 cttgacctgc cggtgcaggg aggaacggct gacccgggcg gagaagtggc accagtcctc
    12601 gccggggacg atcgggcagg cggcgctgtg cgggcagggg gcggcgatgt ggaagccggc
    12661 atcgatgagg cggtcgcggg cctcgatgac gcgggcgtag ccgtcggggg tgccgggctc
    12721 gatgatcacg acggcctggg cggcggtcgc ggcggcgtcg acgacggcgg tgcggtcggc
    12781 ggcggtcagc tcgccgagga cgtacgagac ggtgacgaga tcagtgctct cgattctgag
    12841 cgccgatccg atacgagagc gctgccactc ggcggccttc agctccgggt tcgcggcggc
    12901 gatctcccgc cccagcgcca acgccggctc cgcccagtcc agcaccgtca ccggccgccc
    12961 gcccgcccag gtcgcgttca cggcccaggt cgcggcgccc gtacccccgc cgacgtccac
    13021 atggctgccg ggcacccacc ccggcacggc caccgcgaac gcctccagcg ccgagcacac
    13081 cgcctcgaac gtcgccggca tccgatacgc cgcgtacgcc accacgtccg ccctgtcccg
    13141 caacaccgga gcatccgtcg gcgtccgccc ccgatacttc gcgatcagcc gctccaccgc
    13201 ctgcgtggcc gccttcggcg gcagcccgtc gaggagggcg gcgagggctg cgcggagggt
    13261 gtcggcgggg gatgcggagg aaggggaaag gggggcgttc acgtggtgat tctagggcga
    13321 cccgcgatgc cggactcaga ccttctccac caccacgcgc ggatggccgg cgaggagcat
    13381 gccgatgtcc tccgcgtcgg aggtcaagac ggccacccgg cccgatcgcc gcaccacggt
    13441 cgcgcacagc atggcgtcct gccgggcgcc gggcacggct gccgcgtacg ccacgagggc
    13501 cggagctgcc ggttcccgcg tcggatccga gatcccgccc ctgtacggcc gcctacgatg
    13561 tgccggcgct catcagttgt cgtcctcatc gatgaggaac ccacgcatca tcgacgggct
    13621 cttgcccatc ggcggcggcg acggcgcctg cggccagacc ggagccatcg gctggctcat
    13681 ggtcggagac atttgctgct ggcttccata ggagggggcg ctcccgccac ctccatagga
    13741 cgaagcgctc gcgctgcccg gaatcgaggt gttgttccca gcctgcaggc cggcgagcga
    13801 ttcctcaagc gaactcatcc gtttcgcctg gtcccgtacc agggccacca actcattgag
    13861 gatttccggc atttcgcgct ccgggacggc agtcggcatc tgctcggatc tgatcgcgtc
    13921 gagcttctct tcgagatcac cccagaatct ctcgaaggtc acggccagcc gatcctgctc
    13981 gactgtcatc tcgcatttgt cattgaggct cttgacgagc gcccagactt cgtcccgcga
    14041 actcccctcc gtggcctgga actgggcaat cgggcccgag aggtccttga ccgccagatc
    14101 gacgagaaag ggagcgagcc tcgtctcccc cagttccttc gaaagggcac ccgactcgaa
    14161 attgatccac ggcgcgtgct ggttgtcgcg cgtgacgcac acgattccgt acatacagtc
    14221 ctggagtttg ttcgcgatct tggccagtcc ccgttcgcct ttggagatgt cctgtgacga
    14281 aacgaagggt tcgatcgccg ggttcatgta cgggagccag tcccgcagca cctccgcaca
    14341 acgcctcgaa gcatcgcccg accaactgat gaaaatgcgc atgctggttc cccttgccca
    14401 catggccatc gtcccggtga ccaggatgcc caagggccga cgcccgtacc ccgcgatcgc
    14461 ccggactcgc tcaagccccc cgcaccgccc gagccacccg agtccccgcc gccgctctcg
    14521 ccgcgttgat cgggccccgg cggcgcggat gcaccgcgtt cgtgagcagg atcaggaacg
    14581 tgtccgtcgc cgggtccagg accagggacg taccggtgaa gcccgtgtgg ccggcggcgc
    14641 cccggcccga cagttcgccc atgaaccacg gctggtcgag ggcgaagccc aggcccggcg
    14701 gggtcagcat cagttccacg aagtcggggc cgagaatgcg ggcggggccg taggagccgc
    14761 cggccaggag ggtgcggcag aagacggcca ggtcccgggc ggtcgagaag aggcccgcgt
    14821 ggccggcgac tccgccgagg gaccaggcgt tctcgtcgtg gacctcgccg cggagcatgc
    14881 cccggtccgc cttggcccag gggcggcgtt ggtcctcggt ggccgcggcg gtggggcagg
    14941 ggccgaagac ggtggaggtc atgccgaggg gatgggtgat gccgtcgcgg atcaggacgt
    15001 ccaggcggcg ggcggtgagg cgttcgagga ggtgttggag gagcaggagg ttcaggtcgg
    15061 agtaggcgta ggccgtgccg ggcgcggcga tcggggactc cgcctggagc atcgccaggc
    15121 gggcgtccgg cgtcaggcag tcgtacagcg gcagttcggg gcgcaggccg gaggtgtggg
    15181 tgagcagctg ccgtacggtc aggccgtgtt cggcggcgcc ggtgaagtcg gggaggtacg
    15241 cgcccacctt cgcgtcgatg ccgagggtgc cgcgttccag ttgctggacc gcggcgaccg
    15301 cggtgaagag cttggtgagg gaggcgaggt cgaagggcgt gtcgggcgtc gcggggagcc
    15361 aggactcggg cggcggttcc acgccccggt cggtgcgttc gtcgtaggcc tcgtagcgga
    15421 ccgcccagcc cgccgcctcc tcgacggcga tgacggggcc ccggccggcg atgacgacgg
    15481 cggcgggggc cgacgggcgg tccccttccg tcagcgcgcg cacctcccgt acgagatggc
    15541 gcagttcctc ggggtcgagt ccggcccgtt cggggatgtc cgtgcgcagt ctcggcgcgc
    15601 tcagctctcc tcccccaatc tctcggctcc gctggagagg cgggtacccc catcctccag
    15661 cgtcgtacgc ctgttccaag gacggcacag tgccacgaag catgtggcgg ccaccagtgt
    15721 cgcggccagt tggacgacgg ccatcgggac ggcggtgtcc tcgcccgcga cgccgaccag
    15781 cggggacgcc accgcgccga tcaggaagga cgaggtaccc atcagggccg acgcggaacc
    15841 cgccgcgtgg cggacccgca tcagggcgag ggtctgggtg ttggggaggg cgatgcccat
    15901 ggcggccatc aggacgaaga gggccgcggc gaccggggcg aggcccacct cgccgaaggc
    15961 gcccagggcc atcagcagca gggcggtcgc ggacagggtg acgatcgcga ggcccaccgc
    16021 gaacaccttg tccagactca cccggcctac gagcaccttg ccgttgatct ggcccgcgat
    16081 gaccaggccg accgagttga cgccgaagag gaggctgaag gtctgcgggg aggcgccgta
    16141 gatctcctgg atcacgaacg gggaggcgct gacgtaggcg aagagcgcgg cgaaggcgaa
    16201 gccgccggcg aggacgtagc ccatgaagac gcggtcggtg agcaggccgc gcatcgcgtg
    16261 cagggtctcg ccgatgccgc cgctgtgccg gtcggcgggg gcgagggtct cggggagccg
    16321 cgtccagacg accgccagca gcgcgacgcc gatgaccgtg aggacgacga acacgccccg
    16381 ccagtccgtc acccgcagga tctggccgcc gatgagcggc gcgacgatcg gggccacccc
    16441 ggagatcagc atcagcgtcg agaagaagcg ggccatcgcc tcgccgtcgt acaggtcgcg
    16501 tacgaccgcc cgtgcgatca cgatcccggc cgagccggcg aggccctgca ccaggcggag
    16561 ggcgatcagc gtctcgacgg tcggggcgag ggcgcacagg accgtggcca cgatgtacac
    16621 ggcgaggccc agcagcagcg ggcgcctgcg gccccagcgg tcgctcatcg ggccgatcag
    16681 cagctggccg agggccatgc cggcgaggca cgcggtgagg gtcagctgga cggtggtggc
    16741 gggcgcgtgc agcgagtcgg tgacctccgg aagcgccggg aggtacatgt ccatcgccag
    16801 gggcggggtc gcggtgagac cgccgaggac gagggtgacg aggagaccgg tacggcggag
    16861 ggcggcgggg ctcggtttcg acggctgggg gctcggcctc gacgaccggc ggctcggcct
    16921 cgacgaccgg cggctcggcc tcgacgaccg gcggctcggc ctcgacgacc ggcggctcgg
    16981 cttcgatgac agagggctcg gcttcgacgg ttccgtgccc gacgtcacct gccccggtgc
    17041 gagccccggt tcgggcgccg ctgtggtcga ctcggccatc ggctcggcca tcggctcggc
    17101 catcggctcg gccatcggct cggccatcgg ctcggccatc ggcttcggct cggccggcgc
    17161 cgagcccggt atgtgcccct cgggcat
//
