LOCUS       reptomyces_RBGC_188851 16969 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_188851
VERSION     Streptomyces_RBGC_188851
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000717795.1
  ORGANISM  GCF_000717795.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..1149)
                     /protein_domains="PF02350"
                     /protein_domains="TIGR00236"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518892"
                     /pseudo=False
                     /translation="MTSSTDRTVAVVLGTRPELVKLAELIRLLGPAARVVHTGQHYDDA
                     LSGAFLDELRLPEPEYLTGVGGQPRAVQVAAALAALDERFAAEPPLAVVVQGDTNAALS
                     GALVANARSIPLIHVEAGLRSHDRAMPEEHNRVVIDRLADVLCAATPQNRALLLAEGVS
                     DERIAVTGNTVVEAVRDNLPPRRERARLLGGLGLEADGYVLATVHRPENTDDPAALSAV
                     LGELGAISRTLRVVLPLHPRTAARIEAAGLRSLLDGMTVIDPTAYGTFLALARHAALLV
                     SDSGGVQEETTVLGRPLVVVRRSTERPEAFADFAELVAPGPGIGEAARRRLAEGPRGLR
                     RLASLPSPYGDGTASRCIAELITRVIPSDTPRTAVPGPLVAA*"
     CDS             complement(1266..2056)
                     /protein_domains="PF00072"
                     /protein_domains="PF00486"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518893"
                     /pseudo=False
                     /translation="MLVDWRRPAVAPGARVGPSRLRWWTVPKLLIVEDDAATVVALRGL
                     LVSAGYEVASAADGREGLRLLFSERPDLMVLDLMMPGLDGWRVMARARDMSDLPVLVVS
                     ALDAVGYRVRALRGGADDFVVKPFHGEELVARVEALLRRAGHRQWAGERVGEHLRLVPE
                     RRAVVWYGGEVRLSDIEYRLLQLLVRNRGRVVTTKQLLTRVWGDESAVDGERVKFGVLR
                     LRRKLRGAAGPGGRDPVEAVRGLGYRFISAEEADSDREKGP*"
     CDS             2790..3439
                     /protein_domains="PF02469"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518894"
                     /pseudo=False
                     /translation="VTAFRYRRAALALTAATVLPLALSACGGGGSSDTADKAASSAPAE
                     EKSSAPAEGAVPADGPFGPACASVPKDGAGSFDGMAQDPVATAASNNPDLSTLVTAVKK
                     AGLVDTLNNAQNITVFAPTNDAFAKIPKADLDKVLADKEMLTSILTYHVVGEKLSPTQL
                     ESGTYDTLQKSPLTTKGSGENYTVNDTSKVVCGNVPTANATVHIVDTVLMPKA*"
     CDS             3755..4260
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518895"
                     /pseudo=False
                     /translation="VANDVAALTAELTDMAAADHRSAVHANSDDPAEQLAWRRLTARHG
                     DRLNEIMEEYGWPTADLVGEEAARAAWLVAQHADRQLDVQRRALQLMRQAVSAGSAGPR
                     ELAFLHDRTLVNEGGKQIYGTQIAGVKDGAPVPWPCEDPERVDELRADVGIEPFDAYVA
                     QFSVA*"
     CDS             complement(4595..5703)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518896"
                     /pseudo=False
                     /translation="MHVRTSALSRRPGQAVLLVLGLLAALLAAAVPVAGPAHAAVPDRW
                     GFAYLDNATPPPGYVPDPSRQYGSWASPSTNPVKVDQIGLGSYVVHFPLIGGPGGIAHA
                     TAVSSLARWCQIADWKPVGSGQDVYVTCYLPSGAPANSTFTVLYTSSSGLPTTPTGSYG
                     YVNADSSGAILAQYNSTGAANAVSKGSTGLWKAWLPGLGQATHAGNLQATAVDPKQGAR
                     CKVSDWAPGTTGQTVVVACYNASDVPYDTEWTLSYSYQRAVHGPAFPPRSFGYLWYNGS
                     LPALTNYNSSGATNTLGGSGAPFVVSLPSIAVPSDTAQVTAYGKSPEYCGLHTPWDRAG
                     GTVRLYVACFGPGGAPVKTPFFAAYTSAR*"
     CDS             6258..6463
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_5518897"
                     /pseudo=False
                     /translation="MSDNTISITVELHGGPLDGQSTSVTLTEEDPWVALPNDGCTFPGG
                     RSIYAPDTNGRWVWQDDQPADIP*"
     CDS             6507..6760
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518898"
                     /pseudo=False
                     /translation="VVDRIRVTGAWPTDLAAALPCREEEALLGALRQPDYPALASCPIC
                     DEPPESVVSCVEDPTADGCSVVLVDFKPCRHGIRVPTDA*"
     CDS             7013..8328
                     /protein_domains="PF00067"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518899"
                     /pseudo=False
                     /translation="MSVDRTACPGQPSVPPGEGMLTHSRALRFWLDPANLAARLEQAGP
                     VVPTRTGPATAFQVNDPALLRKIGTDEDTFRFWGPDPSLRDFTEDGVVGLEGAAHRKRR
                     AVMRPAFSASRLTTLGPAAQARTRRLLAGLPADRPLDMRMEMSRLACGLLVSCVLNSEL
                     APDTLSRIAAARSTLSSGMFWRYALAPWPWVPVPRRRACRRALAELDEAVRQLLARHQP
                     HPDGRDLVSVLEAATPENPRVVQRDVRALLIAGMETSASTLAWACYELGRHPHYQQALR
                     DEADAAPDPSRLQADQLPLATAFVQEVTRLHGIPFLVRRTRHQTVQGGVRIPAGAVVTL
                     PLGALRRDRDRYRDPDAFDPKRWLPHAEPPPAPTALLAYGLGPRYCPGAAAADAMLPVA
                     LATLAGSRTLRPARPNRKIGMSLELTPTPKGLTMYATPH*"
     CDS             8427..9100
                     /protein_domains="PF08044"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518900"
                     /pseudo=False
                     /translation="MTRDGDASMPGESLPSGNHAGPGSPPELRASHADRDRVVEVLRVA
                     AGDGRLTADELDERLDGALSARTLGELTALTDDLPSTADSLGAAVAEVKDVLRIEQKHS
                     PVTRSGRWVVPRRLVLDVKWCAVTLDFTRAVITQDTLRIDMDMRGKTLTLITGPGMVVD
                     ADALRLDYSRVRIRTAPDHGEPISLRIELVGEKKHGRVVVRPARRTLGQWLRGPASPGG
                     HG*"
     CDS             9233..9816
                     /protein_domains="PF00440"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518901"
                     /pseudo=False
                     /translation="VARTKEFDPDAALQSALELFWRRGYEATSMTDLVEHIGIGRASIY
                     ATFGSKHELYLKALDRYTETHDPLLMSELSQPGPALPAVRTLVRRFAAEAASPEGRLNG
                     CFVTNTAAELAPHDAAAGRRVEFSWEHIETLLHSALVRAQAQGELPEGRDPRALARMLL
                     VLLQGVRIVGKASNDPARVRDAAEQALTLLD*"
     CDS             9895..11240
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518902"
                     /pseudo=False
                     /translation="MTVTGTARVTATRHGRAFALLGCVQATLIYTLTAIAVPLPRLARE
                     LGLHRSDMILLSTAYGLTFAGLLLFGGRLADRYGGRRILVAGLALFALASVAVPLAPGI
                     EALLAARFAQGAGAALVAPAAMAVLRAVHPSPAAYGRAMATWGGLSVLGATAGNLLSGV
                     ISELLSWRWAFGVPVVVAIVALVLTPRLLPDTAPDRGRRLDLPGALLATAGIVLVSYGL
                     VATDARPASSAGVLVPLLGGAGLLAAFRYAERHSRDPLLPPGFLSGRRRSLALAAVALS
                     ACGTAMTFVVLSLHLQQERDWSPLQTSAAFVPFAVALLASGRAAGPLIGRYGARTVMTA
                     GLGTGAVGLVLLSVTGLSAHTSYAYGLLPGLVLLPAGTAASFAGAAMLATDGVPRQETG
                     LAGGVLNTAMEFGPTVLFAVLLTLDSDPWSLAATGAALAVAALLNHRTK*"
     CDS             11267..12024
                     /protein_domains="PF13561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518903"
                     /pseudo=False
                     /translation="MNRFTGRTVLVTGAGSGLGRAIALAFAAEGASVVAAGRTAASLDE
                     TVGLIGAAGGTAAAVTADVTDSGQLRDLVRESVARFGGLDVAVNNAGIFRGTVPAGEVS
                     EEDWDAVLRTNVTGVWLAMKHEIAHMKENGGGTIVNISSNLGAHLRIPNAAAYITSKAA
                     VSALTRAAALDHIHQGVRINAVSPGASAAPMSLRPGETEADRAERMKSENPLGRVAEAE
                     EVAAAVLYLASPAAGAVVGTDLVIDSGSSA*"
     CDS             complement(12319..12656)
                     /protein_domains="PF00085"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518904"
                     /pseudo=False
                     /translation="MAQRVHRPREDAEFDFILGMSRVPVLAYFTGSWPKAIEPCRAMDL
                     VVGGIADDCAGRLTVVRADITRCPSATRRYGVTGAPTCVLLKEGEAVAHGTGPMTVAEV
                     RELLAGHL*"
     CDS             complement(12695..13857)
                     /protein_domains="PF13556"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518905"
                     /pseudo=False
                     /translation="VSHAIRRASELALDETTVTALRSALRTTADEIVQAIIDEVPSYAN
                     ALSGRMGATIRRAVRTALGHYLDLASGIATGGDGGDAAYELGRGEVRDGRSMDALLSAY
                     RVGARVAWRCLAAGAVPAGLPAAEVAKFAELTFAYIDELSAASAAGHADELAARGRAHE
                     RHLEHLARDLLAGASPDVLLASGQRAGWQPPVSLTAVLLPAPQARPAYRTLDPNTLVLD
                     DLPDATGVLLVPDADRSHLLRQLTDRTAVVGPARPWARASASYARAARARSLSPDIRDT
                     EDHLPELVLSADMDAFADLRARALAPLRALPAATARRLEETLRAWLLHQGRRDEVAAEL
                     FVHPQTVRYRMSQLRELFPDLPSPHRVLELTLAVGLRAAPAGAPREG*"
     CDS             13990..14999
                     /protein_domains="PF00970"
                     /protein_domains="PF00175"
                     /protein_domains="PF00111"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518906"
                     /pseudo=False
                     /translation="MVTTPLLPSDYLDLVSPLRAGADLCGRIEAVRPETGDAATVVIRP
                     GRGWRGHTAGQYVRIGVDVDGVRLWRAYSLTSPAHRQDGRITITVKAIPDGRVSNHLVR
                     RAKPGTLVRLDQPTGDFVLSRTAPAEVFFLTAGSGITPVMGMLRDRELDDVVMVHCAPR
                     PQDVIFREELHALVAAGRLRLTEVHTATDGVLDIARLDELVPDWAERETWACGPTGLLD
                     AAEDHWSEYGVQERLHTERFRPGVVVAGEGGEVTFSASGRTVAADGATPLLDVGEEAGV
                     LMPSGCRMGICFGCVTRLKAGAVRDLRTGGITEAEPGVLIQTCVSAAAGPCDIER*"
     CDS             15008..16125
                     /protein_domains="PF00487"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518907"
                     /pseudo=False
                     /translation="LTAIDPTAHLTAEQIEELGRELDAIRDEVIADRGEKDAAYIRKVI
                     AAQRKLELVSRGVLLFSMFPPAWLLGTAGLSVAKIMDNMEIGHNVLHGQWDWMRDPKIH
                     STTWEWDHVSPSDQWKHSHNELHHTYTNVIGKDNDLGYGIMRVDEDQKWHPFHLGQPLW
                     NFLNACFFEYGIAAYDLELGKNLHKRRRRNPEFRTRARAVGRKIRKQVLKDYVIHPLLS
                     GPSFLTTLGATFTANLVRNLWTHSVIMCGHFPEGVQVFERRSIEGETRGQWYLRQMMGS
                     ANISGSKAMHFMTGNLSHQIEHHLFPDLPSNRYAEVAVKVRALFEKYELEYVTGPLPKQ
                     VFSAWHKVFRLALPNRKPLVGTADREQELVAA*"
     CDS             complement(16257..16969)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_5518908"
                     /pseudo=False
                     /translation="MDVIELARALVLERHPDARAAFLGGSVLTSRRTARSDLDVVVLLD
                     GPPAPYRASLRYGDWPVELFVHTEESWHDFVTPEIVRRNSPLLWMCADGALLLDADGTG
                     ARISDTAERLAAAGPPPVTATALEDARYALTDLLDDFGACTDAGERLFVVADLVRRSAE
                     LALLTHGTWLGGGKWLARRLEPVAPDLAARLDEAARAALRGEQAALTSLVTEVLDAAGG
                     PVWEGYRRSGPRETA*"
ORIGIN
        1 tcaggcggcg accagcggac cgggaacggc ggtacgcggc gtgtcggacg ggatcacccg
       61 ggtgatcagc tccgctatgc agcgggaggc cgtgccgtcg ccgtacgggc tggggaggga
      121 tgccaggcgg cgcagtcccc gcggtccctc ggcgaggcgg cggcgcgccg cctcgccgat
      181 accggggccg ggtgcgacca gttcggcgaa gtcggcgaac gcctcgggcc gttcggtgga
      241 ccggcggacc accacgaggg ggcggcccag cacggtcgtc tcctcctgca ctcccccgga
      301 gtcggagacg aggagcgcgg cgtgccgggc gagcgcgagg aacgtgccgt acgcggtcgg
      361 gtcgatcacc gtcatcccgt cgaggagcga ccgcaggccc gcggcctcga tccgggccgc
      421 ggtgcgcggg tgcagcggga ggacgacgcg cagcgttcgg ctgatcgcgc ccagctcgcc
      481 cagcaccgcg ctcagcgcgg ccgggtcgtc ggtgttctcc gggcggtgca cggtcgccag
      541 cacgtaaccg tccgcttcca gaccgaggcc gccgagcagt cgtgcgcgtt cccgccgtgg
      601 cggcaggttg tcgcggaccg cctccacgac ggtgtttccg gtcaccgcga tccgctcgtc
      661 gctgacgcct tcggccagca gcagcgcccg gttctgcggg gtcgccgcgc acaggacgtc
      721 ggccagccgg tcgatgacca cccggttgtg ctcctcgggc atcgcacggt cgtggctgcg
      781 cagccccgcc tcgacgtgga tcagcgggat cgaccgggcg ttggccacga gggcgccgga
      841 gagggccgcg ttggtgtcgc cctggacgac gaccgcgagc ggcggctcgg cggcgaaccg
      901 ctcgtcgagc gcggccagag ccgccgcgac ctgcacggct cggggctgcc cgcccacacc
      961 ggtcagatac tccggttcgg ggagacgcag ctcgtcgagg aaggcgccgg acaacgcgtc
     1021 gtcgtagtgc tgtccggtgt gcacgacccg ggcggcgggg ccgagcaggc ggatgagctc
     1081 ggcgagcttg accagctcgg gacgggtacc gaggacgacg gcgaccgtac gatctgtgga
     1141 ggaagtcatg acccgagctt tgctggacac ggttgccgca accggtgcgc tggggttgct
     1201 cgaaggttgc tcaatccgtt ttcaactgat tcaggacctt ggtcccggta tttcgtcccg
     1261 gagatcaggg gcccttctcc ctgtcggaat cggcctcttc cgcggaaatg aagcggtatc
     1321 ccagcccccg caccgcctcg accgggtccc gccctcccgg gccggcggca ccgcgcagct
     1381 tccggcgcag acggagcact ccgaacttga cccgctcgcc gtccacggcg ctctcgtcgc
     1441 cccacacccg tgtcagcagc tgtttcgtcg tgacgacccg gccccggttg cgcacgagga
     1501 gctggagcag ccggtactcg atgtcgctga gccgcacctc accgccgtac cagaccacgg
     1561 ccctccgctc gggaacgagc cgcagatgct cgcccaccct ctcgccggcc cactgccggt
     1621 gcccggcacg acgcagcagc gcctcgacgc gcgccaccag ctcctcgccg tggaacggct
     1681 tcaccacaaa gtcgtcggct cccccgcgca acgccctcac ccggtacccg accgcgtcca
     1741 gggccgaaac caccagaacc ggcagatcgc tcatgtcacg ggccctggcc atcacccgcc
     1801 agccgtccag accgggcatc atcaagtcca ggaccatcag gtcgggccgc tcggagaaca
     1861 gcagacgcag gccctcacgg ccgtcagcgg cgctcgccac ctcgtacccc gcgctcacga
     1921 gcagtccgcg cagcgccacg acggtcgcgg cgtcgtcctc cacgatcagc agcttgggca
     1981 ccgtccacca ccggagtcga gacgggccga cccgggcccc cggtgcaacg gccggcctcc
     2041 tccagtcaac cagcatgggc accctctcgc agccggagcg atcaggggct ccggccgctt
     2101 tccccgaccg cttcgtcccg caacgctttc cggggagccg ctcctccggg acactgcccg
     2161 aggccgcgac ccggcgtggt cgagggagac gacgcgccgg ccctccggca gacgccacgg
     2221 cgaccacgcc gtgggacagc cgcctcgcac cgacagcagc gtcgagggac cggtccgtct
     2281 gttgtggggc gcccaggaga gtggcgcccc acaacagccc cttcccacga gccttccacc
     2341 gcggggaggg aggcgaggcg ccccgcagcc gccggggaac ctcgccgtgc gcggtgcctc
     2401 ctcctgacag ccgctcacat cgggtattcg ccgccgccgg gacgccggat tggtcgggac
     2461 cggcacacca cccggtcggc cccatccccg ggcggagcac caggcgccgg ggcatgaccg
     2521 gatgaacttt cttccccgcc gaccaatccg gtcgcgcggc ggctccggat agcagacatg
     2581 acgatcagag cgacacggcc gatccgcccc acagcgaacg tggctctcga cctgctccac
     2641 ggacgagcgc tctgatcccg agtcaccccc tgccacgggg tgacacctga cccgacatca
     2701 gcactgcgga gcatcgccac cagtcgccgg accacacccc tcggcgaaca cgcagagtca
     2761 tcaaccagac acgccaggag ataatgtcgt gaccgccttc cgttaccgcc gcgccgccct
     2821 cgccctcacc gcggcgaccg tcctccccct cgccctgagc gcctgcgggg gcggcggttc
     2881 gtccgacacc gccgacaagg ccgcgagctc cgcccccgcg gaggagaagt cgagcgcacc
     2941 ggccgagggc gccgtccctg cggacggccc gttcgggccg gcctgcgcct ccgtcccgaa
     3001 ggacggtgcg ggctccttcg acggcatggc ccaggacccg gtcgccaccg cggcctccaa
     3061 caacccggac ctgtccaccc tggtcaccgc ggtgaagaag gccggcctcg tcgacaccct
     3121 caacaacgcc cagaacatca cggtgttcgc gccgaccaac gacgccttcg ccaagatccc
     3181 caaggccgac ctcgacaagg tcctggccga caaggagatg ctcaccagca tcctcaccta
     3241 ccacgtcgtc ggcgagaagc tctcccccac gcagctggag agcggcacct acgacaccct
     3301 ccagaagtcc cccctcacca ccaagggctc cggcgagaac tacaccgtca acgacacctc
     3361 gaaggtcgtc tgcggcaacg tccccaccgc caacgccacc gtccacatcg tcgacaccgt
     3421 cctcatgccc aaggcctgac cagcagcggt ccgcgccgag ccccgagtcg ccccccagcg
     3481 gctcggggct ccttccgacg ccgacaaggg ctgacgacgg cagtgtgacg acaggacctg
     3541 ggccgcttcg gtccgggtgg tgcagcgctc gcatgaccct cacgccaggg ggcgtggccg
     3601 tggccgtggc cggctccggt ttcgggggta gatccattat cccggtgcga cggggtgcct
     3661 gtcaccgttc tccagaatga tcttaatacc ccatttgcgc ccttaggctt ggcgggacgg
     3721 tcaccaagta ccgacctgac aagggagttg agagtggcga acgacgttgc cgcactgacg
     3781 gcggaactca cggacatggc tgcggccgat caccggtcgg cagtccacgc gaacagcgac
     3841 gaccccgccg agcaactggc ctggcggcgg ctgaccgccc ggcacggtga ccggctcaac
     3901 gagatcatgg aggagtacgg ctggccgacg gcggacctgg tcggcgagga ggccgcacgc
     3961 gcggcatggc tcgtcgccca gcacgccgac cggcagctcg acgtccagcg gcgcgccctc
     4021 cagctgatgc ggcaggccgt gtcggcaggc tcggccggcc cgcgcgagct cgccttcctg
     4081 cacgaccgca ccctggtcaa cgagggaggc aagcagatct acggaactca gatcgccggc
     4141 gtgaaggacg gggcgccggt cccgtggccc tgcgaagatc ccgagcgcgt ggacgaactc
     4201 cgtgcggacg tcggcatcga gcccttcgac gcgtacgtgg cccagttctc cgtggcgtga
     4261 cgcccctcgc ggacggcggt tcgtcagcgg caacgggccc gggggcgacg tggacttcgc
     4321 agccgacggg tgcaacgtcc tcggcctccg gaggcgcgct cgtccggtcc gtagcccccc
     4381 ggtccgcgta gggatgccgg gggccaggga ttgtcccccg gctccccgaa cgggtgggac
     4441 cgcgtcgagc ggcggcagga gctgggggac gtcgtgccgg tcggcaccgg tgatcgtgac
     4501 ggccggcggg gttccgtgcc ggtcggcgat cggttgtcga ggtgcgcggt tggtctcagg
     4561 tcagcgtgct gcggtgcagc ggttcgcctc gggtcagcgt gccgaggtgt aggcggcgaa
     4621 gaacggggtc ttcaccgggg cgccacccgg gccgaaacag gccacgtaga gccggaccgt
     4681 gccgccggcc ctgtcccacg gcgtgtgcag gccgcagtat tcggggcttt tcccgtaggc
     4741 ggtgacctga gcggtgtccg acggaacggc gatcgacggc aggctcacga cgaagggcgc
     4801 tcccgagccg ccgagggtgt tggtggctcc gctggagttg tagtttgtca gggcgggcag
     4861 cgatccgttg taccagaggt agccgaagga cctcggcgga aaggccggtc cgtgcaccgc
     4921 tcgctggtag gagtagctca gggtccactc ggtgtcgtac ggaacgtcgg aggcgttgta
     4981 gcaggcgacc acgaccgtct gcccggtcgt gcccggcgcc cagtcggaca ccttgcaccg
     5041 cgcgccctgt ttcgggtcca ctgccgtggc ctggaggttt cccgcgtggg tggcctgtcc
     5101 gaggccgggg agccacgcct tccagagacc ggtggagccc ttgctcaccg cgttggcggc
     5161 acctgtcgag ttgtactgcg cgagaatcgc accgctgctg tccgcgttca cgtagccgta
     5221 ggaaccggtg ggcgtggtcg ggagaccgct gctgctggtg tacaggacgg tgaaggtgga
     5281 gttggccggc gcgccgctgg ggaggtagca ggtgacgtag acgtcctggc cggagcccac
     5341 gggcttccag tcggcgatct ggcaccagcg ggccaagctg ctcacggcgg tggcgtgggc
     5401 gatgccaccc ggtccgccga tcagggggaa gtgcacgaca taggagccga ggccgatctg
     5461 gtcgaccttg acggggttgg tggacgggga ggcccaactg ccgtactgcc gtgacgggtc
     5521 ggggacgtaa ccgggcggcg gggtcgcgtt gtccagatac gcgaagcccc agcggtccgg
     5581 tacggcggcg tgggcggggc cggccacggg tacggccgcg gccagcaggg cggccaacag
     5641 accgagtacg agcaggacgg cttggccggg tcttctcgac agggctgagg tgcggacgtg
     5701 catgggcgtg cctcctgtgc ggtgaggggg ggtactgcct gcgcgatccg gtgctgtggt
     5761 cccgaacgtc cgagatgcgt cgtggggcgg ggagcgccct ggtgcggccc tcggcggctc
     5821 tgcgaggacg ggcggtgagg gctctccgac ggtgccccgg gggctcgaag accggtgctc
     5881 actgttccag aagtacggtg ctccgctgag cgttcggcca gccgttccgg tgctgtccgc
     5941 acctgcccca atgacaccgc gggccagtct gttccccagg cacgctgggt ggatcagccg
     6001 cttcggccgc tgccctgtca ccgggcgtat caccccgccc ctctcatccc tgctccagcc
     6061 gccgcgcgtc accaccgcgc ctggccgaaa ggcgccggtt ccctccgcgg ggagtgcggc
     6121 gctccggagt ggcggcggcc tctcccctcc tcgtgggcac ggtgcgcggg gcggtcgccg
     6181 ggccgggcaa ggcccggatc ggcaccgccc cgatccaccc ataattggtc tgtacctgtc
     6241 ggggcagacg atcggcatga gcgacaacac catctcgatc acagtcgaac tgcacggcgg
     6301 accactggac gggcaatcca cctccgtgac cctcacggag gaggacccct gggtcgcgct
     6361 tcccaacgac ggctgcacct tcccgggcgg aagaagcatc tacgcgcccg acaccaacgg
     6421 ccgttgggtg tggcaggacg accagccggc cgatatcccg tgaccccgcc cgcatgccgt
     6481 tggcacggca gcaaccggag gagcagtggt ggaccgcatc cgcgtcacag gcgcgtggcc
     6541 gaccgacctc gcggcggcct tgccgtgcag ggaggaggag gcgctcctcg gagcccttcg
     6601 gcaacccgac taccccgcgc tcgcgtcgtg tccgatctgc gacgaacccc cggaaagcgt
     6661 cgtgtcgtgc gtcgaggacc cgaccgccga cgggtgctcg gtggtcctcg tggacttcaa
     6721 gccctgtcgg cacggcatcc gggtccccac ggacgcgtag cggacctccc gagcgtgtgg
     6781 cccatcgcgc gtcccccgcc ccggggcccg gagcagccgg gtgctcggcg ggatcgccgt
     6841 cacagggctc cgtcccgtga tgggtgacgc tgccccggtt ccggcgacgc gcgggggagc
     6901 ccgcccaccc gtgaccaccc cggcggttga tcgttgccca cacgtactgg cggccgtcac
     6961 cggcggtcgg agccgcgaag gccgacgaac gtgaacagga cagcgaagct gatgagtgtg
     7021 gacaggacag cctgccccgg acaaccgtcc gtgccgcccg gcgagggaat gctcacccac
     7081 tcgcgcgcgc tgcggttctg gctggacccg gccaacctcg cggcccgcct cgaacaggcg
     7141 ggcccggtcg tcccgacccg aacaggcccg gcgaccgcct tccaggtcaa cgacccggca
     7201 ctcctgcgta agatcggcac cgacgaggac accttccggt tctggggccc ggacccgagc
     7261 ctgcgcgact tcaccgagga cggggtggtc ggcctcgaag gcgccgccca ccgaaagcgg
     7321 cgcgccgtca tgaggcccgc gttcagcgcg tcccggctca ccacgctcgg gcccgccgcc
     7381 caggcccgga cccggcggct gctcgccggc ctgcccgcgg accggcccct cgacatgcgg
     7441 atggagatga gccggctcgc ctgcggcctc ctcgtcagct gcgtcctcaa cagcgaactc
     7501 gctcccgaca ccctgtccag gatcgcggcc gcccgctcca ccctgtccag cggcatgttc
     7561 tggcggtacg ccctcgcgcc ctggccctgg gtgcccgtgc cccggcgccg cgcctgccgc
     7621 cgcgcgctcg ccgaactgga cgaggccgtc cgtcagttgc tggcccgcca ccagccccac
     7681 cccgacggcc gggacctggt gtccgtgctc gaagccgcca cgcccgaaaa cccccgcgtg
     7741 gtgcagcgcg atgttcgcgc gctgctgatc gccggcatgg agaccagcgc ctccaccctc
     7801 gcctgggcct gctacgaact gggccgccat ccgcactacc agcaggcgct ccgggacgag
     7861 gccgacgccg cgcccgaccc gagccgcctc caagcagacc aactcccgct cgcgacggcc
     7921 ttcgtgcagg aggtcacccg gctccacggc atcccgttcc tggtccgccg cacccgccac
     7981 cagaccgtcc agggcggtgt ccggatcccg gccggagccg tggtcaccct gcccctgggg
     8041 gcactgcgcc gcgacaggga ccgctaccgc gacccggacg cgttcgaccc gaagcgctgg
     8101 ctcccccacg ccgagccgcc accggccccc accgcgctgc tcgcctacgg cctgggcccc
     8161 cggtactgcc ccggcgcagc cgcggccgac gccatgctgc cggtcgccct ggcgaccctg
     8221 gccggctcgc gtacgctccg cccggcgcgg ccgaaccgca agatcggcat gagcctggaa
     8281 ctcacgccga cgcccaaggg cctgaccatg tacgccacac ctcactgacg accgggcccg
     8341 gtcgaggcgg agtcgcccgc tcccgggctt ggtgggcgtc cacgtcgcgc tatagcgttg
     8401 gcccctccgg tcgggaccga cggccatgac gagggacggg gacgcaagca tgccgggaga
     8461 gagtctgccc tccgggaacc atgccggtcc gggttccccg cccgaactgc gggcctctca
     8521 cgcggaccgg gaccgtgtcg tggaagtgct gcgtgtcgcg gcgggcgacg gtcggctgac
     8581 cgcggacgag ttggacgagc gcctggacgg cgccctgtcg gcgcgaaccc tcggcgagct
     8641 gacggcactc accgacgatc tgccgtcgac ggcggattcg ctcggtgccg cggtcgcgga
     8701 ggtcaaggac gtgctccgca tcgagcagaa gcacagcccc gtcacgcgtt cgggacgctg
     8761 ggtggtgccg cggcggctgg tgctcgacgt gaagtggtgc gcggtgacgc tcgacttcac
     8821 ccgggccgtg atcacgcagg acaccttgcg gatcgacatg gacatgcgcg gcaagaccct
     8881 gacgctgatc accggaccgg gcatggtggt ggacgccgat gccctgaggc tggactacag
     8941 cagggtcagg atccgtaccg ctccggacca cggtgagccg atctcgctgc gcatcgagct
     9001 ggtcggcgag aagaagcacg gtcgcgtcgt cgtgcggccc gcgcggcgaa cgctggggca
     9061 gtggcttcgc gggcccgctt cccccggtgg ccacggctga atccccggtc gccacggctc
     9121 ggatggagag cggtggcacc gcgcttcgcg tcgtgatccg cacacaggaa cggccgatgc
     9181 gacgacctcg ataattgacc gaacggtcca gatagggcta gggtcttcgc tgtggccagg
     9241 accaaggaat tcgatccgga cgccgcgctg cagtcggctc tcgagctgtt ctggcggcgg
     9301 ggctacgaag cgacgtcgat gaccgatctc gtcgaacaca tcggcatcgg ccgcgccagt
     9361 atctacgcga cgttcggcag caagcacgag ctgtacctca aggccctcga ccggtacacc
     9421 gagacgcacg acccgctcct catgtccgag ctgtcccagc ccggtcccgc cctgcccgcg
     9481 gtgcggacgc tggtgcgccg cttcgccgcg gaagccgcgt ccccggaagg gcggctgaac
     9541 ggctgcttcg tcaccaacac cgccgccgag ctggccccgc acgatgccgc ggcgggccgc
     9601 cgggtcgagt tcagctggga gcacatcgag accctgctgc actccgcgct cgtgcgggcc
     9661 caggcccagg gagagcttcc cgaggggcgc gatccgcgag cgctggcgcg catgctgctc
     9721 gtcctgctgc agggcgtgcg catcgtgggc aaggcgtcga acgatcccgc ccgggtgcgg
     9781 gacgccgccg aacaggcact gaccctgctg gactgagtcg cacccgacag agccgacggg
     9841 tcgctttcgc acgcccgaat aatggaccga tcagtcaaat atcgggggga atcatgacgg
     9901 tcacgggcac cgcccgcgtc accgccacgc ggcacgggcg cgccttcgcc ctcctcggct
     9961 gcgtccaggc cacgctgatc tacacgctca ccgcgatcgc cgtaccgctg ccccgcctcg
    10021 cccgggaact cggcctccac cgctcggaca tgatcctgct cagcaccgcc tacggcctga
    10081 ccttcgccgg gctgttgctg ttcggcgggc gtctcgccga ccgctacggc gggcggcgca
    10141 tcctcgtcgc gggccttgcc ctcttcgccc tcgcctcggt cgccgtcccg ctcgcccccg
    10201 gaatcgaagc cctgctcgcg gcgcgcttcg cccagggcgc gggcgcggcc ctggtcgcac
    10261 cggccgccat ggccgtgctg cgcgccgttc acccctcccc cgccgcgtac ggcagggcga
    10321 tggccacctg gggcgggctc tccgtgctgg gcgcgaccgc gggcaatctg ctctccggcg
    10381 tcatctcgga actgctctcc tggcgctggg cgttcggcgt acccgtcgtg gtggcgatcg
    10441 tggcgctcgt cctcacgccc cggctgctgc cggacaccgc acccgaccgg ggcaggcgtc
    10501 tcgacctgcc cggtgcgctg ctcgccaccg ccgggatcgt cctcgtcagt tacggtctcg
    10561 tcgccaccga cgcccgcccc gcgtcctcgg ccggcgtact ggtgccgttg ctcggcgggg
    10621 ccgggctgct ggccgcgttc cggtacgccg agcgccattc ccgcgatccc ctgctgcccc
    10681 ccggtttcct gtccggccgg cggcggtccc tggccctcgc cgccgtcgcg ctgagcgcct
    10741 gcgggaccgc gatgaccttc gtggtcctct cgctccacct ccaacaggag cgcgactggt
    10801 caccgttgca gacctcggcc gccttcgtac cgttcgccgt ggcgctgctc gcctcgggcc
    10861 gggcggcggg tccgctcatc ggccggtacg gcgcccgaac ggtcatgacc gccgggctgg
    10921 gtacgggcgc ggtcgggctc gtcctcctct cggtcacggg gttgtccgcg cacacctcgt
    10981 acgcgtacgg gctgctgccg ggcctcgtgc tgctgccggc gggcaccgcg gcgtccttcg
    11041 ccggagccgc catgctcgcc accgacggcg taccgcggca ggagaccggg ctcgcgggag
    11101 gcgtgctgaa caccgcgatg gagttcggcc cgaccgtcct cttcgccgtc ctgctcacac
    11161 tcgacagcga cccctggtcc ctggccgcga caggggccgc cctggccgtc gcggccctcc
    11221 tgaaccaccg caccaagtag cccgtcactc aagggagtca ccgaaatgaa ccgcttcacc
    11281 ggcaggaccg tcctcgtcac cggcgcggga tccggcctcg gccgcgccat cgcgctcgcc
    11341 ttcgccgccg agggcgcgtc cgtggtcgcc gcgggacgta ccgcggcgtc cctggacgag
    11401 acggtcggcc tcatcggggc ggccggtggg acagccgccg ccgtcaccgc cgatgtcacc
    11461 gactccggac agctccggga cctcgtccgg gagagcgtcg cccgcttcgg cggcctggac
    11521 gtggcggtca acaacgccgg gatattccgg ggcaccgtgc ccgccggcga ggtgagcgag
    11581 gaggactggg acgcggtact gcggaccaat gtcaccggcg tctggctggc catgaagcac
    11641 gagatcgccc acatgaagga gaacggcggc ggcaccatcg tcaacatctc ctccaacctg
    11701 ggcgcacacc tgaggattcc gaacgccgcc gcgtacatca cctccaaggc ggcggtgtcc
    11761 gcgctgacgc gtgccgccgc gctcgaccac atccaccagg gcgtccgcat caacgccgtc
    11821 agccccggcg cctccgccgc tcccatgtcg ctgcgtcccg gtgagaccga ggccgaccgt
    11881 gccgagcgga tgaagtcgga gaacccgctc ggacgcgtcg cggaggccga ggaggtggcg
    11941 gcagcggtgc tctacctcgc ctcgcccgcc gccggtgcgg tcgtcggcac cgacctggtc
    12001 atcgacagcg ggtcgtcggc ctaacggttc gcggggcggg gcgcctcctc cccggggagc
    12061 ggtgcggccg aggcggtcgc ccccgccggg tgcccccgcc gtgagccgga ccggcggggg
    12121 cagggccttg cctccgcctc tgtcgcacag tgccccggga cgcctgaagc gccccagggc
    12181 gacgtcggca cggcgttctc ggccgacgcg gccccgtggt cacggcgtga tgtgacgtgg
    12241 cgtgcagggc cctgaccgga tgcggcgaca ggtggcgcga tgtgacgggt ttcgcggcca
    12301 cctgccgcac cggccgatca gaggtggccg gccaggagct cccgtacctc ggcgacggtc
    12361 atgggccccg tgccgtgcgc caccgcctcg ccctccttga gcaggacgca cgtcggggct
    12421 ccggtgaccc cgtatctccg ggtcgcggac gggcaacgcg tgatgtcggc gcggacgacc
    12481 gtcaggcgcc ccgcgcagtc gtcggcgatg ccgcccacga cgaggtccat cgcccggcag
    12541 ggctcgatcg ccttgggcca gctaccggtg aagtacgcga ggaccggaac tcggctcatc
    12601 ccgaggatga aatcgaactc cgcgtcctca cggggccggt gaacccgttg tgccatggaa
    12661 gctcctgccc tcacgttccg tcgttccgtc ccatcatccc tcgcgcggtg cgccggccgg
    12721 cgcggcccga agaccgacgg ccagcgtcag ttccaggacc cggtgcggcg acgggaggtc
    12781 cgggaacagc tcccgcagct gcgacatccg gtaccggacc gtctggggat ggacgaacag
    12841 ttccgccgcc acttcgtccc gtctgccctg gtgcagcagc cacgcccgca gcgtctcctc
    12901 cagccgccgc gcggtcgcgg cgggcagggc ccgcaagggt gcgagggcgc gggcgcgcag
    12961 gtcggcgaag gcgtccatgt cggcgctcag caccagctcg ggcaggtggt cctcggtgtc
    13021 gcggatatcg ggggaaaggg agcgggcacg tgcggcgcgg gcgtacgagg cggacgcacg
    13081 cgcccacggc cgggccgggc cgaccacggc tgtgcggtcg gtcagctgcc gcaggagatg
    13141 tgatcggtcg gcatcgggga cgagcaggac acccgtggca tccggcagat cgtcgagcac
    13201 cagggtgttc gggtcgagcg tgcggtaggc gggccgggcc tggggtgcgg gcagcaggac
    13261 cgcggtcagc gaaaccggag gctgccaccc ggcccgttgg ccggaggcca gcagcacgtc
    13321 cgggctcgcg cccgcgagga ggtcgcgggc caggtgttcc aggtggcgct cgtgggccct
    13381 gccccgggcg gccagttcgt cggcgtgccc cgcggcgctc gcggcggaga gctcgtcgat
    13441 gtaggcgaag gtcagctcgg cgaacttggc gacctcggcg gcgggcaggc ccgcgggtac
    13501 cgcccccgcc gccaggcacc gccaggccac gcgggcgccg acgcggtagg cactgaggag
    13561 ggcgtccatc gaacgtccgt cgcgcacctc gccacgaccc agctcgtagg cggcgtcacc
    13621 gccgtcgccg cccgtggcga taccgctcgc caggtccagg tagtgcccca gggcggtgcg
    13681 gacggcccgg cgaatggtgg cgcccatgcg gcccgagagg gcgttggcgt aggacgggac
    13741 ctcgtcgatg atcgcctgga cgatctcgtc ggccgtggtc ctcagagcgc tccgaagggc
    13801 ggtgaccgtc gtctcgtcga gggccagttc gctggccctc cggattgcat ggctcacttt
    13861 ttgttccctg cgaacaattc agctgatcgg tttcacgtcc tgcggtcagg actttacgcc
    13921 atggggcgca gcaagctggg gccatgacga gtacagccct ccgcagtagg gcgtggaaac
    13981 tactggagat ggtcacgacg ccgctgctgc cgtcggacta cctcgacctg gtcagcccgc
    14041 tgcgtgcggg ggccgacctg tgtggtcgta tcgaggccgt gcgtcccgag acgggtgacg
    14101 ccgcgaccgt cgtgatcagg ccggggcggg gctggcgcgg tcacacggcc ggtcagtacg
    14161 tgcggatcgg ggtcgacgtc gacggggtgc gcctgtggcg tgcctactcc ctcacctcgc
    14221 cggctcaccg ccaagacggc cgcatcacga tcaccgtgaa ggcgatcccg gacggccggg
    14281 tcagcaacca tctggtccgc agggcgaagc cgggcacgct ggtccggctc gaccagccga
    14341 ccggggactt cgtgctgtcg cggaccgcgc ccgccgaggt gttcttcctg acggccggca
    14401 gcggcatcac gcccgtgatg ggcatgctgc gcgacaggga gctcgacgac gtcgtcatgg
    14461 tccactgcgc gccgcggccg caggacgtga tcttccgcga ggagctgcac gctctggtcg
    14521 cggccgggag gcttcggctc accgaggtgc acaccgcgac ggacggcgtg ctcgacatcg
    14581 cccgtctcga cgagctcgta cccgactggg ccgagcgcga gacctgggcc tgcgggccga
    14641 cgggcctgct cgacgccgcc gaggaccact ggagcgagta cggcgtccag gagcgtctgc
    14701 acaccgaacg cttccgcccc ggcgtcgtcg tcgcgggcga gggcggcgag gtcacgttca
    14761 gcgcctccgg cagaaccgtc gcggcggacg gcgccacgcc gttgctggac gtcggcgagg
    14821 aggccggtgt gctcatgcct tccgggtgcc gcatgggcat ctgcttcggc tgcgtcacgc
    14881 ggctcaaggc gggcgccgtc cgcgacctgc gcaccggcgg gatcaccgag gccgagccgg
    14941 gcgtcctcat ccagacctgc gtgtccgccg ccgcgggccc gtgcgacatc gaacggtagg
    15001 agcaccttga ccgccatcga ccccaccgcc cacctgaccg cggagcagat cgaggaactg
    15061 ggccgcgagc tggacgcgat ccgcgacgag gtgatcgccg accgcggcga gaaggacgcc
    15121 gcctacatcc gcaaggtcat cgcggcgcag cgcaagctgg agctggtcag caggggcgtg
    15181 ctgctgttct cgatgttccc gcccgcgtgg ctgctcggca ccgccggact gtccgtggcg
    15241 aagatcatgg acaacatgga gatcggccac aacgtcctgc acggccagtg ggactggatg
    15301 cgcgacccga agatccactc caccacctgg gagtgggacc acgtctcgcc gtccgatcag
    15361 tggaagcact cgcacaacga actgcaccac acgtacacca acgtgatcgg caaggacaac
    15421 gacctcggct acggcatcat gcgcgtcgac gaggaccaga agtggcatcc cttccacctc
    15481 ggccagccgc tgtggaactt cctcaacgcc tgcttcttcg agtacggcat cgcggcgtac
    15541 gatctggagc tcggcaagaa cctccacaag cgccgccgcc ggaatccgga gttccgcacg
    15601 cgggccaggg ccgtgggacg caagatccgc aagcaggtgc tcaaggacta cgtgatccac
    15661 ccgctgctgt cgggcccgtc cttcctcacc acactcggcg ccacgttcac cgccaacctg
    15721 gtccgcaacc tctggaccca ctcggtgatc atgtgcgggc acttccccga gggcgtacag
    15781 gtcttcgagc gccggtccat cgagggcgag acgcgcggcc agtggtacct gcgccagatg
    15841 atgggctcgg cgaacatcag cggcagcaag gccatgcact tcatgaccgg caacctgtcg
    15901 caccagatcg agcaccacct gttcccggac cttccgagca accggtacgc cgaggtcgcg
    15961 gtgaaggtgc gcgcgctgtt cgagaagtac gagctcgagt acgtcaccgg ccccctgccc
    16021 aagcaggtct tctccgcgtg gcacaaggtc ttccggctcg cgctgccgaa caggaagccc
    16081 ctggtcggca cggcggaccg cgagcaggag ctcgtcgccg cctgatcccg gcaggggttc
    16141 gggccgttcg gccggacccg gcggcgccgg gtccgctccc aggcgtcggg cgcccggagg
    16201 accgaggccg tgccgatggg gccgagcggc gcgtgccgcc cggtcgtccg gccggtcagg
    16261 ccgtctcacg cggtccgctg cggcggtagc cctcccagac cgggccgccg gccgcgtcga
    16321 ggacctccgt gaccagcgag gtgagggccg cctgctcgcc gcgcagcgcg gctcgcgccg
    16381 cctcgtccag gcgcgcggcc aggtccggtg cgacgggttc gaggcgccgg gccagccact
    16441 ttccgccgcc gagccaggtc ccgtgggtca gcagcgccag ctcggcgctc cgccggacga
    16501 gatcggccac gacgaacagc cgctcccccg catccgtaca ggcgccgaaa tcgtcgagca
    16561 ggtccgtcag cgcgtaccgg gcgtcttcga gcgccgtcgc ggtgaccggg ggcgggcccg
    16621 cggcggcgag gcgttcggcc gtatccgaga tccgtgctcc ggttccgtcg gcgtcgagca
    16681 gcagcgcgcc gtcggcgcac atccacagca ggggcgagtt ccgccggacg atctccgggg
    16741 tcacgaagtc gtgccaggac tcctcggtgt gcacgaacag ctccaccggc cagtccccgt
    16801 accgcaggct cgcgcggtac ggggcgggcg ggccgtcgag cagcacgacg acgtccaggt
    16861 cggaccgggc ggtgcgccgg ctcgtcagga cgctgccgcc gaggaacgcc gcgcgggcat
    16921 cggggtggcg ctccagaacg agagctcggg cgagttcgat gacgtccat
//
