LOCUS       reptomyces_RBGC_216016 16575 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_216016
VERSION     Streptomyces_RBGC_216016
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_004115015.1
  ORGANISM  GCF_004115015.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..978)
                     /protein_domains="PF01408"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364559"
                     /pseudo=False
                     /translation="MTERPLRVAVLGTADIARRRVLPAMAEDPDVELTAVASRSGARAR
                     QLAGRYGCAAVESYDAVLDRDDVDAVYVPLPVSLHAEWARSALAAGKHVLAEKPLTAHA
                     HTTAELLDLARSSGLALMENVMFVHHPQHSVVRELVAGGAIGELRSFTAVFAVPPLPAD
                     NIRHRPELGGGALLDIGYYPVRAALYFLGTGLDVVGAALEHSDGSAVETSGAVLVRSPD
                     GVLGQLAFGMEHAYRSAYELWGSEGRIRVESAFTPPADHKPTVWVADASGPRELTLAPH
                     DQVAATVRAFVQAARSGGTDPRTAAECLEQARLLDAVRARGAAR*"
     CDS             complement(972..2452)
                     /protein_domains="PF03559"
                     /protein_domains="PF03559"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364560"
                     /pseudo=False
                     /translation="MSSTLTELTRPQPTVQPREPVSVADRIAASAAATAGRMTTDAFHD
                     WFAARGRAGRFSVERIPFSKLRGWSFEPGTGNLVHASGRFFSVEGLHVTTDQGPHLEWY
                     QPIIKQPEVGILGILVKEFDGVLHFLMQAKMEPGNRNLLQLSPTVQATRSNYTKVHKGT
                     DVKYIQYFTGPGRGRILADVLQSEHGSWFFHKSNRNMIVEVDEDVPLDEDFCWLTLGQI
                     NELMHQDNLVNMDSRTVLACLPAHRPQLPSPDEFLSALGRSRDPEAGALLTDVDLLSWF
                     TAERSRYDVRAERIPLSEVPGWTRDEARIGSDDDRWFNVVAVEVQAGNREVSGWTQPLI
                     EPCSRGVAAFVVRSFGGVLHVLANAKVEGGFLDTVELAPTVQASPDNFAGLSVDPPFLD
                     EVLSAGPDRVRYDAIHSEEGGRFLYAENRYLIVEADEAEAPLLPPAGFQWVTVSQLSEL
                     VKHGHYVNVQARTLLACLNAMSAYTYDFMGTRAHD*"
     CDS             complement(2538..3838)
                     /protein_domains="PF01041"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364561"
                     /pseudo=False
                     /translation="MSDTKSQILEQVRDYHLEKEPSRTFVPGVDEIWPSGAVLGPEDRV
                     ALVEAALDMKIAAGTHSRRFESRFARYMKRRKAHLVNSGSSANLLALSALTSPHLEDRR
                     LKPGDEVVTVAAGFPTTVNPIIQNGLVPVFVDVELKTYNTTAERIKSAIGPKTRAIMIA
                     HALGNPFEVAEVAQIAEENDLFLIEDNCDAVGSLYGGRLTGTFGDLTTVSFYPAHHLTM
                     GEGGCVLTANLALARIVESMRDWGRDCWCEPGENNRCFKRFEYQLGTLPQGYDHKYIYS
                     HVGYNLKATDLQAALGLTQLDKVDEFTAARRHNWSRLREGLDGAPHLILPEATLGSEPS
                     WFGFVITVAPEAPFTRKELVDHLEKHKIGTRNLFAGNLTRQPAYQDVPHRIVGDLTNSD
                     VITEQTFWIGVYPGLTDEMTDYMIATIREFVAGR*"
     CDS             complement(3832..4781)
                     /protein_domains="PF01370"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364562"
                     /pseudo=False
                     /translation="VGGHVCRAFAAAGWRVAGVARSTPDTPAAYAIHGLDLARAAPEQI
                     TALVRGHGADVVVNAAGAVWGATEAEMDLSNRDLVRRLVAARPPRLIQLGSVHEYGPVP
                     RAGITEAGPTAPVTPYGRSKLAGARALLDSGTEGLVLRVSNVSGPGTSPLSLLGMVAAH
                     LARDSGEPLRLAPLLAHRDFVDVRDVADAVLAAASSKATGRAVNIGGGHATSVREVVAR
                     LVALAGRDTRIVETPVAGARPPEAEWQRLDITLADRLLGWRPRISLDESLRDLLAEAHC
                     HSPSSAVRAGTPTMSATGHHQRPRAGLTHGGRKYE*"
     CDS             4991..5604
                     /protein_domains="PF00908"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364563"
                     /pseudo=False
                     /translation="MRIEETAVPDAYRITPRLLPDERGSFHESYRYDVLAAETGHSFLP
                     RQVNYSVSSRNTVRGLHGVSIPPGQAKLVSCVRGVVLDVVVDVRVGSPTFGRHDCTVLD
                     ARSGRGVYVAEGLAHGFVALTDDTCISYLCSTEYVPGTQLDLRAFDPELGLPWSKWLTG
                     DPLLSEKDANAITVAEATERGLLPSYEQCQEFYAAAVRTPA*"
     CDS             complement(5698..7235)
                     /protein_domains="PF01494"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364564"
                     /pseudo=False
                     /translation="VTTSAPQVLVVGAGPVGLSAAHELARHGVRVRLVDAADGPATTSR
                     ALATHARTLETYDQMGVLDELLSRGQRVEHFTLHQNGRRLIRFDTDYSRLPTRFPFTLM
                     VDQVITEEVLRDAAARLGVTVEWGVRLDGFEDLGEDGVRARLTGPGGRTETVAADWLVG
                     ADGGHSTIRKQLGLKLAGESSETWLIADAVVDCDLPKDSIHWMRTPRGTVMMVPFPDEG
                     KWRLLDTAETSYGGDDRMVAERFAAKITAGTGKPAQVELPSWVSVFTIQQRMIPSMRQG
                     RVLLAGDAAHVHSPASGQGMNTGVQDAVNLSWKLAAVLRGEADDTLLDSYSAERVPVGA
                     ELLRTTRMATLLVQLRSRKAAAFLRTAFTVLRNLPPLKDRIQRKIMGGMSALGLGYGES
                     PLTVAASAPGIRPGERLARVDAAGAASAQWRTVLDELRRPDWLLLSNGATHHRSLRTVR
                     ITDASVAADLGLRDGDWLLVRPDGYVAARGDAGQSPRAALQSLGIRVRETAELA*"
     CDS             complement(7233..8242)
                     /protein_domains="PF16363"
                     /protein_domains="TIGR01181"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364565"
                     /pseudo=False
                     /translation="MSKKILVTGGAGFIGSHYVRTLLQDGYEGYEDAEVTVLDKLTYAG
                     NRDNLPAEHPRLTFVRGDIGDLPLLLELFPGHDAVVHFAAESHVDRSLESAAEFVTTNV
                     GGTQNVMEAALRSGVERVVHVSTDEVYGTIDEGSWTEEWPLLPNSPYAASKAGSDLIAR
                     AYWRTHGLNVSITRCSNNYGPYQHPEKLIPRFVTNLLEGETVPLYGEGANIREWLHVDD
                     HCRAIQLVLTRGRAGEVYNVGGGNEQTNRQITERLLELTGNDWSKVVRVADRKGHDLRY
                     SLDESKIQRELGYAPRTSFEEGLAATVAWYRDNPGWWKPVKHGTEDKHGTEEEGK*"
     CDS             complement(8240..9306)
                     /protein_domains="PF00483"
                     /protein_domains="TIGR01208"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364566"
                     /pseudo=False
                     /translation="MKALVLAGGTGSRLRPFSYSMPKQLIPIANKPVLEHVLDNIRDIG
                     VTEIGIIVGNHATEIADALGDGSRLGVAITYIPQERPAGLAQTVQLARGFLGDDDFVMY
                     LGDNMLPEGIQEAAAEFRALQPAAQVLVAQVEDPRAFGVAEVDTHGVVERLVEKPPVPR
                     SNLALIGVYFFTPAIHEAVDSIEPSARGELEITDAIQWLVTAGRTVRAQEYAGYWKDTG
                     KVEDVLECNRMLLDAVARSVEGEVDEDSVLIGPVVVEPGARIVNSFVVGPVVIGAGTVL
                     EDSHVGPYTSIGRDCVLTDAHLDRSIALDGSTVSGVRGLRGSLLGRSAAVTGAQLEERH
                     HRLVVGDHTRVEVAA*"
     CDS             complement(9367..9911)
                     /protein_domains="PF03358"
                     /protein_domains="TIGR03567"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364567"
                     /pseudo=False
                     /translation="MPTILAVSGSPSPVSLTHRVLTRAAERLGGRGHLVDVLAVRALPS
                     GPLLAADTAHAEIDSAVRQFTQADAVVLATPVYKAGYSGLLKTFLDLLPQFALDGKVVL
                     PLATGGSLAHVLALDYGLRPVLMSMKPAAVAESLFVHAEQAEADTARAQLDAATDRFAE
                     LVEALHRPTRRHLTPAAA*"
     CDS             complement(9929..11061)
                     /protein_domains="PF00296"
                     /protein_domains="TIGR04020"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364568"
                     /pseudo=False
                     /translation="MNADADTRQSDSPPPGGPPDFGVFFFAAVGDRSEETYQLMLDAAR
                     RADALGFGFVSTPERHFHRFGGAFPNPAVTSAAVAAVTRRIQIRAGSVVTPLHPASRIV
                     EDFAVVDGISGGRAAISVGSGWNVNDFVIAPDKYETRREQMAKDVADIREAWRTGRWTG
                     PTPLGTEATLPLYPRPVQPELPVWVTASRSEGTFVEAGRMGCNILTHLENQDTDSLAGK
                     IALYRAARAESGQDGPGTVTVMMHTYVAEDPETARTVGGGALRDYLLSAIDLEAGAVQA
                     GGRMSGNKEGRDVLSAARAQRKLADLGVNRYLSGNSLIGSVEECARTARRVRAAGVDEI
                     ACLVDFVRDPAQVLASLELLDAVRRDTARADEPVAAR*"
     CDS             complement(11059..11222)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MVRVGAQPAEGEAEAAGTANLPNLPALKPRTSTPPDGDREHSTHP
                     PRAEGGSTG"
     CDS             11722..13247
                     /protein_domains="PF00501"
                     /protein_domains="PF13193"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364569"
                     /pseudo=False
                     /translation="MTTQTLVAADTVDGLLAAAVAARPDAPAVRDVAGSWTYAELDAWS
                     RAYADWFTARGVGRGDRVLARVGNVREFTALLFGALRRGIVFVPVNPAMKRFHLSTVVP
                     DCEPVMLIAQRAEDVELLRELTDRPVVPLAHARAGAEQQFGGGVHEDVAVDPDDLGLLI
                     YTSGSTSAPKAVASPHAPIVFAARAIQARLKYREDDVVLAAVPLSFDYGLYQIFLSVIA
                     GAQLVLTEPDRHVRLLGALHEYGVTVVPLVPSLAEMLLTLARRDRREPPPVRLFTNTGA
                     ALTAPVIARLRKCFPQAQVSPMFGTTECKRITVLEPDGDLEKPGSVGRALDGTEVLVLD
                     DEGRPLPPGTVGEIAVRGPHMMRGYWRAPEQTALRFRPDPVTGEVTLHTGDYGHLDADG
                     HLYFEGRRDDLFKRKGVRMGTLEIETAALDIPGVAAAAALAPADGHDLTLYAVTDLTPA
                     AVLAQLAERLEAAKVPAACHLLDALPLTPNGKTDKQRLRREQNAGQVRPD*"
     CDS             13261..13526
                     /protein_domains="PF00550"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364570"
                     /pseudo=False
                     /translation="MTTAMTRPDPDFEQLLVGVLPRLAGSGPLDPALDLKEAGLDSMAT
                     IELLVRLEDTYEVEFPEETLTAATFATPAALWSVLSAQRAAAH*"
     CDS             13575..13669
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364571"
                     /pseudo=False
                     /translation="MNIAHLCIGLGVTVVACLIAKFGGAALRNRR*"
     CDS             complement(13746..14908)
                     /protein_domains="PF06722"
                     /protein_domains="PF00201"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364572"
                     /pseudo=False
                     /translation="VRVLMLSTPFPTHFTPMVPLAWALKGAGHEVTVAAQPDVTDAARA
                     AGITAVDIGERFHGLDVLQRHLPPGVRPLELMGPTPPEKMAGATKLWETHARYLLGSYL
                     EFARDWCPDLVVSEQMELTGSVVAAVLGVPSVQHRWGVDPLSGPSRASARDFLHGAVTR
                     LGLTGLPDPGLLLDPCPPALRHPSAARGVPIGYVPFNGVGTVPEWLLRPAPEGTRRVVV
                     CLGGQTLQLNGTGLFRSIIAAFDGLGDVQAVVTAAPEFHEGFGPLPANVRVVEPSPLNL
                     FLRDCDAVVHHGGANTTMTACSFGLPQVVLPQLVDQFASAELLCAAGAALSLTEAEPQN
                     DPERVRAVLTEVLDDDRYRKGARVLADDMARMPSPARVVEDLELLAA*"
     CDS             complement(14906..16575)
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4364573"
                     /pseudo=False
                     /translation="VSVPVTENPSADDTAGAAVAQDEKKNPYGMSDMRILVFMVCAMTT
                     MVLSLLDESIVASAVLPIVRDLDPAHGIDRFPWLITAYLLTATAAQPLYGRLSDSFGPR
                     RVYLTSLATFLAGSALCATAGSLTQLIVFRAVQGLGGGGLMSMTLIVIATLYPPKSRAG
                     RSNAGGALVAAGMIAGPMIGGPLSQEVSWRWIFLVNVPVAALALAGVTWALKLPPKHTR
                     QSVDVLGSALLAGATCSLLLAVKAYDHGGYGPWIGWAYTALAMTASFVVRQKKAADPLI
                     PVALFRDRVFRPAAALQFIAGFALLALPVFLINYLNIVRGVDLDTVGLHLIPMALGVVV
                     VFFGWGNWISRTGRCKPVLTVTTATAVVATAGLGLSISDLPMWELDVLLVLLGIGLGGI
                     SQIALFMNQSAAAPEQLGVVTTASRFATMLGTTIGGGLLGVVLSARFASAADGLGVTNP
                     EAAAARIAGLPAAGRHRVMDAYAQATGAVLLTAAGLLLLALITALLMPDVDLESADAAH
                     RDGADAAHRDGADGADEQQETPEPAEHATVSTERAEEAA*"
ORIGIN
        1 tcatcgggcc gccccccggg cgcgtacggc gtccagcagc cgggcctgtt ccaggcactc
       61 ggccgccgtg cgcgggtcgg tgccgccgga gcgggccgct tgtacgaagg cccgcacggt
      121 ggcggccacc tggtcgtgcg gtgcgagggt cagttcgcgg gggccgctcg cgtcggcgac
      181 ccacaccgtc ggcttgtggt cggcgggcgg ggtgaacgcg gactcgacgc ggatgcggcc
      241 ctcgctgccc cacagttcgt acgccgagcg gtaggcgtgc tccatcccga acgcgagctg
      301 tccgagcacg ccgtcggggg accgtacgag cacggcgccc gaggtctcca ccgccgagcc
      361 gtccgagtgc tccagggccg cgccgaccac gtcgaggccg gtgcccagga agtacagggc
      421 ggcccgcacc gggtagtagc cgatgtcgag cagggcgccg ccgcccagtt cggggcggtg
      481 gcggatgttg tccgcgggca gcggcgggac ggcgaacacc gcggtgaacg aacgcagttc
      541 gccgatcgcg ccgcccgcca ccagctcccg taccaccgag tgctgcggat gatggacgaa
      601 catcacgttc tccatcaggg ccaggcccga ggagcgggcc aggtccagga gttcggcggt
      661 ggtgtgggcg tgcgcggtca gcggtttctc cgccaggacg tgcttgcctg ccgccagtgc
      721 gctgcgggcc cactcggcgt gcagggagac gggcaacggg acgtagacgg cgtccacgtc
      781 gtcccggtcg agcacggcgt cgtacgactc gacggccgcg cagccgtagc ggcccgccag
      841 ttgccgtgcg cgtgcgccgc tccggctggc caccgcggtc agctcgacgt ccgggtcctc
      901 ggccatggcg ggcaggacgc ggcggcgggc gatgtccgcg gtgccgagga cggcgacgcg
      961 cagcggacgt tcagtcatgt gctcgggttc ccatgaagtc gtaggtgtag gcgctcatgg
     1021 cgttcaggca cgccagcagg gttctggcct gcacattcac gtagtggccg tgtttgacca
     1081 gctccgagag ctggctgacc gtgacccact ggaagccggc cgggggcagc agcggggcct
     1141 cggcctcgtc ggcctcgacg atcagatagc ggttctcggc gtagaggaag cggccgccct
     1201 cctcggagtg gatggcgtcg tagcggacgc ggtcggggcc ggcggacagc acctcgtcca
     1261 ggaagggcgg gtcgacggac aggccggcga agttgtccgg ggaggcctgc acggtcggcg
     1321 cgagttccac ggtgtccagg aagccgccct cgaccttggc gttggccagc acatgcagca
     1381 cgccgccgaa ggagcgcacg acgaaggcgg cgacgccccg gctgcacggc tcgatcagcg
     1441 gctgggtcca gccggagacc tcgcggttgc cggcctgcac ctcgaccgcg acgacgttga
     1501 accagcggtc gtcgtcgctg ccgatgcggg cctcgtcccg ggtccagccg ggcacctcgg
     1561 acagcgggat gcgctcggcg cgcacgtcgt agcgggagcg ttcggcggtg aaccaggaca
     1621 gcaggtccac gtcggtcagc agcgcgccgg cctccgggtc gcgggagcgg cccagcgcgc
     1681 tcaggaactc gtcgggggag gggagttggg ggcggtgtgc cggaaggcag gccaggaccg
     1741 tgcgcgagtc catgttgacc aggttgtcct ggtgcatgag ctcgttgatc tggccgaggg
     1801 tgagccagca gaagtcctcg tcgagcggga cgtcctcgtc cacctcgacg atcatgttgc
     1861 ggttgctctt gtggaagaac cacgaaccgt gctcggactg cagcacgtcg gcgaggatgc
     1921 ggccgcggcc gggaccggtg aagtactgga tgtacttgac gtccgtgccc ttgtggacct
     1981 tggtgtagtt gctgcgggtg gcctggacgg tgggcgagag ctggagcaga ttgcggttgc
     2041 ccggctccat cttggcctgc atcaggaagt gcaggacgcc gtcgaactcc ttgaccagga
     2101 tgccgaggat gcccacctcg ggctgcttga tgatgggctg gtaccactcc aggtgcgggc
     2161 cctggtcggt ggtgacgtgc aggccctcca cgctgaagaa gcggccgctg gcgtgcacca
     2221 ggttgccggt gccgggctcg aaggaccagc cgcgcagctt cgagaacggg atgcgttcga
     2281 cgctgaaccg gcccgccctg ccgcgtgcgg cgaaccagtc gtggaacgcg tcggtggtca
     2341 tccgtccggc cgtggccgcc gcggacgccg cgatccggtc ggccaccgag accggttcgc
     2401 ggggctggac cgtgggctgc ggacgcgtca actccgtgag tgtcgacgac atgtgcggtc
     2461 tctccttgtc agggcgttcg ggctcaaggg cgttcgggcc catgcgatgg gggggcgcac
     2521 agacggcccc ggggcgtcac cggcccgcga cgaactcgcg gatcgtggcg atcatgtagt
     2581 cggtcatctc gtcggtcagg ccggggtaga cgccgatcca gaaggtctgc tcggtgatga
     2641 cgtcggagtt ggtgaggtcg ccgacgatgc ggtgcggcac gtcctggtag gcgggctggc
     2701 gggtcaggtt gccggcgaac aggttgcggg tgccgatctt gtgcttctcc aggtggtcca
     2761 ccagctcctt gcgggtgaac ggggcttcgg gcgcgaccgt gatcacgaag ccgaaccagc
     2821 tgggctcgct gcccagcgtc gcctccggca ggatcaggtg cggcgcgccg tccaggccct
     2881 cgcgcagccg ggaccagttg tgccggcggg ccgcggtgaa ctcgtcgacc ttgtccagct
     2941 gggtcaggcc gagcgcggcc tgcaggtcgg tggccttcag gttgtaaccg acgtgcgagt
     3001 agatgtactt gtggtcgtag ccctggggca gggtgcccag ctggtactcg aaccgcttga
     3061 agcagcggtt gttctcgccc ggctcgcacc agcagtcgcg gccccagtcc cgcatcgact
     3121 cgacgatccg ggcgagcgcg aggttcgcgg tgagcacgca gccgccctca cccatcgtga
     3181 ggtggtgcgc ggggtagaag ctgacggtcg tcaagtcgcc gaaggtgccg gtcagtcggc
     3241 cgccgtagag ggagccgacc gcgtcgcagt tgtcctcgat caggaagagg tcgttctcct
     3301 cggcgatctg cgccacctcg gcgacctcga aggggttgcc gagtgcgtgg gcgatcatga
     3361 tggcgcgggt cttggggccg atcgcggact tgatgcgttc cgcggtggtg ttgtacgtct
     3421 tcagctcgac gtcgacgaag accgggacca ggccgttctg gatgatcggg ttgacggtgg
     3481 tggggaaacc ggcggcgacc gtgacgacct cgtcgcccgg cttgagcctg cggtcctcca
     3541 ggtgcgggga ggtgagcgcg gacagggcga gcaggttcgc cgacgaaccg gagttcacca
     3601 ggtgggcctt gcggcgcttc atgtagcggg cgaaccgcga ctcgaagcgg cgggagtggg
     3661 tgcccgccgc gatcttcatg tcgagggccg cctcgaccag ggccacccgg tcctcggggc
     3721 cgagcaccgc gccggagggc catatctcgt cgacgccggg gacgaacgtg cgcgacggct
     3781 ccttctccag gtggtagtcg cgaacctgct ccaggatctg tgacttggtg tcactcatac
     3841 ttcctgcctc catgggtgag tccggcccgc ggccgctggt gatgacccgt cgccgacatc
     3901 gtcggcgtcc ccgctcgaac ggcactggat ggcgaatggc agtgcgcctc ggccagcagg
     3961 tcgcgcagcg actcgtccag cgagatgcgc ggacgccagc ccagcagccg gtcggccagg
     4021 gtgatgtcga ggcgctgcca ctcggcctcc ggcgggcgcg cgcccgccac cggggtctcc
     4081 acgatccggg tgtcccggcc cgccagggcg accagccggg ccaccacctc ccgtaccgaa
     4141 gtcgcgtgcc cgccaccgat gttgacggcc cgtccggtcg ccttcgagga ggctgcggcc
     4201 agcaccgcgt ccgccacgtc gcgtacgtcc acgaagtcgc ggtgggcgag cagcggggcc
     4261 aggcgcagcg gctcgccgga gtccctcgcg aggtgcgcgg cgaccatgcc gagcaggctc
     4321 agcggggagg tgccggggcc cgacacgttc gacacgcgca gcaccaggcc ctcggtgccg
     4381 gagtccaaca gggcccgcgc gcccgccagt ttggagcgac cgtagggggt gacgggggca
     4441 gtcgggccgg cctcggtgat gccggcccgc gggacgggtc cgtactcgtg caccgagccc
     4501 agctggatca gccgcggcgg ccgcgccgcc accagccgcc gcaccagatc ccggttgctc
     4561 aggtccatct cggcctcggt ggcgccccac accgctccgg ccgcgttcac caccacgtcc
     4621 gcgccgtggc cgcgcaccag cgccgtgatc tgctccgggg cggcccgcgc caggtcgagt
     4681 ccgtggatgg cgtacgcggc aggggtgtcc ggcgtgctcc gggccacccc cgccacccgc
     4741 cacccggccg ccgcgaaggc gcggcagaca tgaccgccca cgaagcccga cgcgcccagt
     4801 acgagtaccg cgcgcccgcc ctcagctctt cgtccgatcg ccgccaacgt atctcgcccc
     4861 tcaactcgtt cggtgtgggg gcactgtgac ggctgccgct agggcgcggc tggatcaggc
     4921 tttttcccgg tcaccaggga tgtttgcgcg ctaccgggaa tcgagtcctc ccccctacgg
     4981 tcccgaggca tgaggatcga agagacggcc gtaccggacg cgtaccggat caccccgagg
     5041 ctgctgccgg acgagcgcgg cagtttccac gagtcgtaca gatacgacgt tctcgcggcc
     5101 gagacgggtc attcgttcct gccccgccag gtcaactact cggtctcctc ccgcaacacc
     5161 gtccgcggac tgcacggggt gtcgatccca ccggggcagg cgaagctggt cagttgtgtg
     5221 cgcggggtcg tgctggacgt cgtggtggac gtgcgggtcg gctcgcccac gttcggccgg
     5281 cacgactgca cggtgctgga cgcgcgcagc ggccgggggg tgtacgtcgc cgaggggctc
     5341 gcgcacggct tcgtcgcgct caccgacgac acctgcatca gctatctctg ctccaccgag
     5401 tacgtcccgg gcacccagct cgatctgcgc gccttcgacc cggagttggg gctgccctgg
     5461 tccaagtggc tgaccgggga cccgctactg tccgagaagg acgcgaacgc gatcaccgtc
     5521 gccgaggcca ccgagcgggg tctgctgccg tcctacgagc agtgccagga gttctacgca
     5581 gccgccgtgc gcacgcccgc ctgaccgagc cccggccccc gtgggccgac ggcgaaggcc
     5641 cgtagcgact cccttcgggg aatcggtacg ggccttcgtc ttgagtccct tgcggatcag
     5701 gccagttcag ccgtttccct gacccggatg ccgagcgact gcagggccgc gcgcggggac
     5761 tggccggcgt cgccgcgggc ggccacatag ccgtccgggc ggaccagcag ccagtcgccg
     5821 tcgcgcagac cgaggtcggc ggcgaccgag gcatcggtga tacggacggt gcgcagcgaa
     5881 cggtggtgcg tggcgccgtt gctcagcaac agccagtccg ggcggcgcag ttcgtccagt
     5941 accgtccgcc actgcgccga ggcggcaccc gcggcgtcga cccgggcgag gcgttcgccg
     6001 gggcggatgc ccggggcgga ggcggcgacg gtgagggggc tctcgccgta gccgaggccg
     6061 agtgccgaca tgccgcccat gatcttgcgc tgaatacggt ccttcagggg cggcaggttg
     6121 cgcagcaccg tgaacgcggt gcgcaggaac gccgccgcct tgcggctgcg cagctgcacc
     6181 agcagcgtgg ccatcctggt ggtgcgcagc aactctgccc cgaccgggac ccgttcggcg
     6241 ctgtaggagt ccagaagcgt gtcgtcggcc tcgccgcgca gcacggcggc cagcttccag
     6301 gacaggttca ccgcgtcctg gacaccggtg ttcatgccct gcccggacgc cgggctgtgc
     6361 acatgggcgg cgtcgcccgc gagcagcacc cggccctggc gcatgctcgg gatcatccgc
     6421 tgctgaatgg tgaacaccga gacccaggaa ggcagttcga cctgcgcggg cttgccggtg
     6481 cccgccgtta tcttcgcggc gaagcgctcg gcgaccatgc ggtcgtcgcc gccgtaggac
     6541 gtctccgcgg tgtccagcag ccgccacttg ccctcgtcgg ggaacggcac catcatcacc
     6601 gtgccgcgcg gggtgcgcat ccagtggatg ctgtccttgg gcaggtcgca gtcgacgacc
     6661 gcgtccgcga tcagccaggt ctcgctggac tcgcccgcca gcttcagacc gagctgcttg
     6721 cggatggtgc tgtgtccgcc gtcggcaccg accagccagt cggcggcgac cgtctcggtg
     6781 cggccgccgg gtccggtcag ccgcgcgcgt acgccgtcct cgccgaggtc ctcgaagccg
     6841 tcgagccgta cgccccactc gacggtgacc ccgagccggg ccgcggcgtc gcgcagcacc
     6901 tcctcggtga tcacctggtc gaccatgagg gtgaagggga agcgggtggg cagccggctg
     6961 tagtccgtgt cgaagcggat cagccggcgg ccgttctggt gcagcgtgaa gtgctcgacg
     7021 cgctggccgc gggagagcag ctcgtccagc acgcccatct ggtcgtacgt ctccagggtg
     7081 cgggcgtgcg tggccagcgc cctgctggtg gtggccgggc cgtccgccgc gtccaccagc
     7141 ctgacccgga caccgtgccg ggccagctcg tgggcggcgc tgagcccgac gggcccggcg
     7201 cccacgacca gtacctgagg ggcggacgtg gtcacttgcc ctcctcctcg gtgccgtgct
     7261 tgtcctcggt gccgtgcttg accggcttcc accagcccgg gttgtcgcgg taccaggcga
     7321 cggtggcggc gaggccctcc tcgaaggagg tgcgcggcgc gtagcccaac tcccgctgga
     7381 tcttggactc gtcgagcgag tagcgcaggt cgtggccctt gcggtcggcg acccggacca
     7441 ccttcgacca gtcgttgccg gtcagttcga gcagccgctc ggtgatctgg cggttggtct
     7501 gctcgttgcc gccgccgacg ttgtagacct cgccggcccg gccgcgggtg agcaccagtt
     7561 ggatggcccg gcagtggtcg tcgacgtgca gccactcacg gatgttggcg ccctcgccgt
     7621 acagcgggac cgtctcgccc tccagcaggt tggtgacgaa gcgcgggatg agcttctcgg
     7681 ggtgctggta ggggccgtag ttgttggagc agcgggtgat ggacacgttc aggccgtggg
     7741 tgcgccagta ggcgcgggcg atcaggtcgg agcccgcctt ggacgcggcg tagggggagt
     7801 tgggcagcag cggccactcc tccgtccagg agccctcgtc gatggtgccg tagacctcgt
     7861 cggtggagac gtgcacgacc cgctcgacgc ccgagcgcag ggcggcctcc atcacgttct
     7921 gggtgccgcc gacgttggtc gtcacgaact ccgcggcgga ctccagggag cggtccacgt
     7981 gcgactcggc ggcgaagtgc accaccgcgt cgtgcccggg gaagagctcc aggagcagcg
     8041 gcaggtcgcc tatgtccccg cgcacgaagg tgagccgggg gtgctcggcc ggcaggttgt
     8101 cgcggttgcc ggcgtaggtc agcttgtcga ggacggtgac ctcggcgtcc tcgtagccct
     8161 cgtacccgtc ctggagaagc gtgcggacgt agtgcgagcc gatgaagccc gcaccgccgg
     8221 tgaccaggat cttcttgctc atgccgcgac ctccacgcgg gtgtggtcgc cgaccaccag
     8281 gcggtggtgg cgctcttcga gttgggcgcc cgtgacggcg gcggaccggc cgagcagcga
     8341 gccgcgcagg ccgcgcactc cggagacggt cgacccgtcc agggcgatgg agcggtccag
     8401 atgggcgtcg gtcaggacac agtcccggcc gatcgaggtg tacggaccga cgtgactgtc
     8461 ctccaggacg gtgcccgcgc cgatcaccac ggggcccacc acgaaggagt tgacgatacg
     8521 ggcgccgggc tcgacgacga ccgggccgat cagcaccgag tcctcgtcga cctcgccctc
     8581 gacgctgcgc gccacggcgt ccagcagcat ccggttgcac tccaggacgt cctcgacctt
     8641 gccggtgtcc ttccagtacc cggcgtactc ctgggcccgt accgtccgcc cggcggtgac
     8701 cagccactgg atggcgtcgg tgatctccag ttcgccgcgg gcgctcggct cgatcgagtc
     8761 gacggcctcg tggatcgccg gggtgaagaa gtacacgccg atcagggcca ggttggagcg
     8821 cggcaccggc ggcttctcca ccagccgttc caccacgccg tgcgtgtcca cctcggcgac
     8881 cccgaacgcc cgcgggtcct ccacctgcgc gaccagcacc tgggcggcgg gctgcagggc
     8941 acggaactcg gcggccgcct cctggatgcc ctccggcagc atgttgtcgc cgaggtacat
     9001 cacgaagtcg tcgtcgccga ggaagccgcg ggccagctgc acggtctgcg cgaggccggc
     9061 cggacgctcc tgcgggatgt aggtgatcgc gacgccgagg cgggagccgt cgccgagggc
     9121 gtcggcgatc tccgtcgcgt ggttgccgac gatgatgccg atctcggtga cgccgatgtc
     9181 ccggatgttg tcgaggacgt gttccaggac cggcttgttg gcgatcggga tgagctgctt
     9241 gggcatggag tagctgaacg ggcgcagccg cgatcccgtc ccgccggcca gcactagagc
     9301 cttcatgggg gcctcttccg gggagttcgg tgtgacagtc atggggcggt gggtgatgtg
     9361 gtgggtcagg ctgccgccgg tgtcagatgg cggcgggtgg gccggtgcag ggcctccacc
     9421 agttcggcga accggtcggt ggcggcgtcg agttgggctc tcgcggtgtc ggcctcggcc
     9481 tgttcggcgt gcacgaagag gctctcggcc acggcggccg gcttcatcga catcagcacc
     9541 gggcgcagcc cgtagtcgag cgcgagcaca tgggcgagcg agccgccggt ggccagcggc
     9601 aggacgacct tgccgtcgag ggcgaactgc gggagcaggt ccaggaaggt cttcagcagg
     9661 cccgagtacc cggccttgta gaccggggtc gccagcacca ccgcgtcggc ctgggtgaac
     9721 tgccgtacgg cggagtcgat ttcggcgtgc gcggtgtcgg cggcgagcaa cgggccggac
     9781 ggcagggcac gtacggccag cacgtcgacc aagtggccgc gcccgccgag ccgttcggcg
     9841 gcgcgggtga gcacccggtg ggtgagcgag accggcgacg ggctgccgga gacggcgagg
     9901 atcgtcggca tggggcgacc tcctgggtca gcgggccgct acgggctcgt cggcccgcgc
     9961 ggtgtcacgg cgtacggcgt cgagcagttc gagggaggcg agcacctggg cggggtcgcg
    10021 gacgaagtcg accaggcacg cgatctcgtc gaccccggcc gcgcgcaccc ggcgggccgt
    10081 gcgggcgcac tcctcgaccg agccgatcag ggagttgccg gacagatagc ggttgacgcc
    10141 gaggtcggcc agcttgcgct gggcgcgggc cgcggacagt acgtcccggc cctccttgtt
    10201 gccgctcatc cggccgccgg cctgtacggc gccggcctcc aggtcgatgg cggacagcag
    10261 gtagtcgcgc agggcgccgc cgccgacggt gcgggcggtc tccgggtcct cggcgacgta
    10321 ggtgtgcatc atcacggtga ctgtgccggg gccgtcctgg ccggactcgg cgcgggcggc
    10381 gcggtacagc gcgatcttgc ccgcgagcga gtcggtgtcc tggttctcca ggtgggtgag
    10441 gatgttgcag cccatccggc ccgcctcgac gaaggtgccc tcgctgcggg aggcggtcac
    10501 ccacaccggc agctcgggct gcaccgggcg ggggtacagc ggcagcgtgg cctcggtgcc
    10561 gagcggggtg ggcccggtcc agcggccggt gcgccatgcc tcgcggatgt ccgccacgtc
    10621 cttggccatc tgctcgcgtc gggtctcgta cttgtcgggg gcgatcacga agtcgttgac
    10681 gttccagccc gagcccaccg agatcgccgc gcggccgccg gagatgccgt ccacgacggc
    10741 gaagtcctcg acgatgcggg aggccgggtg cagtggggtg accacgctgc cggcccggat
    10801 ctggatgcgg cgggtgacgg cggctacggc ggccgaggtg acggccgggt tggggaaggc
    10861 gccgccgaag cggtggaagt ggcgttcggg cgtcgagacg aagccgaagc cgagggcgtc
    10921 ggcgcggcgt gccgcgtcca gcatgagttg gtacgtctcc tcggagcggt caccgaccgc
    10981 ggcgaagaag aagacgccga agtcgggggg ccctccgggg ggtgggctgt cggactggcg
    11041 ggtgtccgcg tccgcgttca tcctgtgctg cctccttctg cgcgaggggg gtgtgtgctg
    11101 tgctcgcggt caccatcggg gggtgtgctc gtacggggct tgagcgcggg caggttgggg
    11161 aggttcgcgg tgcccgccgc ctcggcttcg ccttcggcgg gttgtgctcc cacccgcacc
    11221 acccgtgaca ctttcgtcgt cgggtgcggg tggcccctgc ggggcttctc gtcgttggcg
    11281 ggtgcgggtg gtccccttgg ggggctggtt gccgttggcg ggtgcgggtg gcccctgcgg
    11341 ggcttctcgt cgttggcggg tgcgggtggc ccctgcgggg cttctcgccg tcggcgggtg
    11401 cgggtggtcc ccgcgagggc aggtcgccgt tggcgggtgc gggtgggccc cgtggggttt
    11461 cccgccgtgg cggttgtcgg tctggggcgt gcggctttgt cgttgggtgc gtggcccccg
    11521 tggcgctgct cgccgtcggc ggttctcccg gaatggcctc ggctcgcccc cgccccgctt
    11581 ctcgccctgg cggcactccc ggaacgtttc tcggccccgc ccccgcgggg gcggctccac
    11641 tggtgttcaa gtctgcggcg gcacgctggg tgggtcctgt ttccgcttcg acggacccga
    11701 tcgccccgcg aggttgctga atgacgactc agacactggt ggccgccgac accgtcgacg
    11761 gcctgcttgc cgcggcggtg gccgcgcggc ccgatgcgcc cgcggtgcgg gatgttgcgg
    11821 gcagctggac gtatgccgaa ctcgacgcct ggtcaagggc gtacgccgac tggttcaccg
    11881 ctcgcggtgt gggccggggt gaccgcgtac tggcccgggt gggcaatgtc cgcgagttca
    11941 ccgccctgct cttcggcgcg ctgcgccggg gcatcgtctt cgtaccggtc aacccggcga
    12001 tgaagcgctt ccacctcagc accgtagttc ctgattgtga gcccgtgatg ctgatcgctc
    12061 agcgcgccga agacgtcgag ctgctacggg agttgacgga tcggcccgtc gtgccgctcg
    12121 ctcatgcgcg ggccggggcc gagcagcagt tcgggggcgg ggtgcacgag gacgtggccg
    12181 tggaccccga cgacctcgga ctgctgatct acacctcggg ctccacctcc gcccccaagg
    12241 ccgtcgcgag cccgcacgcg ccgatcgtgt tcgcggcgcg cgccatccag gcccggctga
    12301 agtaccgcga ggacgacgtc gtcctcgccg ccgtgccgct ctccttcgac tacggcctct
    12361 accagatctt cctctcggtg atcgccggcg cccagctcgt actgaccgaa cccgaccgcc
    12421 acgtacggct gttgggcgct ctgcacgagt acggcgtgac cgtcgtaccg ctggtgccct
    12481 cgctcgccga gatgctgctg acgctggccc ggcgcgaccg ccgcgagccg ccgccggtgc
    12541 ggctgttcac caacaccggg gccgccctga ccgcccccgt catcgcgcgg ctgcgcaagt
    12601 gcttcccgca ggcccaggtg tcacccatgt tcggcaccac cgagtgcaag cggatcaccg
    12661 tcctggaacc ggacggcgac ctcgaaaagc ccggctcggt cggccgcgcc ctggacggca
    12721 ccgaggtgct cgtcctcgac gacgagggcc gcccgctgcc gcccggcacg gtcggcgaga
    12781 tcgccgtacg cggaccgcac atgatgcgcg gctactggcg cgcccccgaa cagaccgccc
    12841 tgcgcttccg ccccgacccc gtcaccggcg aagtcaccct gcacaccggc gactacggcc
    12901 atctggacgc cgacggccac ctctacttcg agggccgccg cgacgacctg ttcaagcgca
    12961 agggggtgcg catgggcacc ctcgagatcg agacggccgc cctggacatc cccggcgtcg
    13021 cggccgccgc cgcgctcgcc cccgccgacg gccacgacct cacgctctac gccgtcaccg
    13081 acctgacccc cgcggcggtc ctcgcccagc tggccgagcg cctggaggcc gccaaggtcc
    13141 ccgccgcctg ccatctgctg gacgcgctgc cgctcacccc caacggcaag accgacaagc
    13201 agcggctgcg ccgcgagcag aacgccggcc aggtccggcc cgactgagga gtacggaaca
    13261 tgaccaccgc catgacccgc ccggacccgg acttcgagca gctgctggtc ggcgtgctgc
    13321 cgcggctggc cggctcgggc ccgctcgacc ccgccctcga cctcaaggag gccggcctgg
    13381 actcgatggc caccatcgag ctgctggtcc gcctggagga cacctacgag gtggagttcc
    13441 ccgaggagac cctcaccgcg gcgaccttcg ccaccccggc ggccctgtgg agcgtcctca
    13501 gcgcccagcg tgccgccgcc cactgaccac accctcacgc acggttcgac ccaacccccc
    13561 aaggagaaac gccatgaaca tcgcccacct ctgcatcggt ctcggagtca ccgtcgtcgc
    13621 ctgcctcatc gccaagttcg gcggcgccgc cctcaggaac cgccgctgaa cctcccgcca
    13681 cggcactggg ccccgaccgg aacatccggt cggggcccag ccctttgccc accgccgcgt
    13741 caggtcatgc ggcgagcagc tccaggtcct cgacgacccg ggccggagag ggcatccgcg
    13801 ccatgtcgtc ggcgagcacc cgcgcgccct tgcggtaccg gtcgtcgtcc agcacctcgg
    13861 tgaggaccgc ccgcacccgc tccgggtcgt tctgcggctc ggcctcggtc agcgacagcg
    13921 ccgccccggc cgcgcagagc agctccgcgg aggcgaactg gtccaccagc tgcggcagta
    13981 cgacctgcgg cagcccgaac gagcaggcgg tcatggtggt gttggcgccg ccgtgatgca
    14041 ccaccgcgtc gcagtcgcgc aggaagaggt tgagcggcga cggctccacc acccgcacgt
    14101 tcgcgggcag cgggccgaac ccttcgtgga actccggcgc cgcggtgacc accgcctgta
    14161 cgtccccgag cccgtcgaag gcggcgatga tgctgcggaa cagcccggtc ccgttgagct
    14221 ggagcgtctg tccgcccagg cacacgacca cgcggcgcgt tccctcgggc gcgggccgca
    14281 gcagccactc gggcaccgtg ccgacgccgt tgaaggggac gtagccgatg ggcacgcccc
    14341 gcgccgcgct cgggtggcgc agcgccggcg ggcacgggtc gagcagcagg ccggggtcgg
    14401 gcagcccggt caggcccagc cgggtcaccg cgccgtgcag gaagtcacgg gcggaggcgc
    14461 gggaggggcc gctgagcggg tcgacgcccc agcggtgctg gacggacggg actccgagca
    14521 ccgcggcgac gacggaaccg gtgagctcca tctgttcgga gacgaccagg tcggggcacc
    14581 agtcgcgggc gaactccagg taggagccca gcagatagcg cgcgtgggtc tcccacagct
    14641 tggtcgcgcc cgccatcttc tccggtgggg tcggccccat cagctccaac ggccgtacgc
    14701 ccggcggcag atggcgctgc aggacgtcca gtccgtggaa gcgctcgccg atgtcgacgg
    14761 ccgtgatgcc cgccgcgcgg gccgcgtccg tgacgtcggg ctgcgcggcc accgtcacct
    14821 cgtggcccgc ccccttcagc gcccacgcca gcggcaccat cggggtgaag tgggtgggga
    14881 agggcgtgct cagcatcagg actctcacgc ggcctcctcg gctcgctcgg tggatacggt
    14941 ggcgtgttcg gccggttcgg gtgtctcctg ctgctcgtcc gcgccgtccg cgccgtcccg
    15001 gtgtgccgcg tccgcgccgt cccggtgtgc cgcgtccgcg ctctccaggt cgacgtccgg
    15061 catcagcagc gcggtgatca gggcgagcag cagcaggccc gccgcggtca gcaggacggc
    15121 gccggtggcc tgggcgtagg cgtccatgac gcggtgccgg ccggccgcgg gcagcccggc
    15181 gatgcgggcc gcggccgcct ccgggttggt gacgccgagg ccgtcggcgg cggaggcgaa
    15241 ccgggcgctg aggaccacgc cgagcaggcc gccgccgatc gtggtgccca gcatcgtggc
    15301 gaaccgggag gcggtggtga ccaccccgag ctgttccggc gccgccgccg actggttcat
    15361 gaacagggcg atctggctga tgccgccgag accgatgccc aacagcacca gcagcacgtc
    15421 cagttcccac atcggcaggt cggagatcga cagaccgagc ccggcggtgg cgacgacggc
    15481 cgtcgccgtg gtgaccgtca gcaccggctt gcaccggccg gtgcgggaga tccagttgcc
    15541 ccagccgaag aagaccacga ccacgccgag ggccatcggg atcagatgca ggccgaccgt
    15601 gtcgaggtcc acgccccgca cgatgttcag gtagttgatc aggaacacgg gcagcgccag
    15661 cagcgcgaaa ccggcgatga actgcagggc ggcggccggg cggaacaccc ggtcacggaa
    15721 gagggccacc gggatcagcg ggtcggccgc cttcttctgc cgtacgacga aggaggcggt
    15781 catcgccagt gcggtgtacg cccagccgat ccacggcccg tagccaccgt ggtcgtaggc
    15841 cttgacggcc agcagcaggg agcaggtggc gcccgccagc agcgccgagc cgagcacgtc
    15901 cacgctctgc cgggtgtgct tgggcggcag cttgagcgcc caggtgacac cggcgagggc
    15961 cagggccgcc accggcacgt tcaccaggaa gatccaccgc caggacacct cctggctgag
    16021 cgggccgccg atcatcgggc ccgcgatcat gccggccgcg acgagggcac cgcccgcgtt
    16081 cgaccgcccg gcacgggact tgggcgggta cagcgtggcg atgacgatga gggtcatgct
    16141 catcagaccg ccgccgccca ggccctgcac ggcgcggaag acgatcagct gggtcaggga
    16201 gcccgcggtc gcgcacagcg ccgagcccgc caggaaggtg gcgagcgagg tcagatagac
    16261 ccggcgcgga ccgaagctgt cgctgagcct gccgtacagc ggctgggccg cggtggcggt
    16321 cagcagatag gcggtgatca gccacgggaa gcggtcgatg ccgtgggccg ggtccaggtc
    16381 gcgcacgatc ggcagcacgg ccgaggcgac gatcgactcg tccagcagcg acaggaccat
    16441 cgtggtcatg gcgcacacca tgaagacgag gatgcgcatg tcactcatgc cgtacgggtt
    16501 cttcttctcg tcctgcgcga cggcggcacc ggcggtgtcg tcggcggacg ggttctcggt
    16561 gacgggcacg ctcac
//
