LOCUS       reptomyces_RBGC_228178 16136 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_228178
VERSION     Streptomyces_RBGC_228178
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001685355.1
  ORGANISM  GCF_001685355.1
            .
FEATURES             Location/Qualifiers
     CDS             2..999
                     /protein_domains="PF02800"
                     /protein_domains="PF00044"
                     /protein_domains="TIGR01534"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951792"
                     /pseudo=False
                     /translation="MTRIAINGFGRIGRNVLRALLERDSTLEVVAVNDLTEPATLARLL
                     AYDSTAGRLGRPVTVDGNTLVVDGRRITVLAEREPAQLPWADLGVDLVLEATGRFTSAK
                     AARAHLDAGARKVLVSAPSDGADVTLAYGVNTDAYDPQVHTIVSNASCTTNALAPLAAV
                     LDELAGIEHGFMTTVHAYTQEQNLQDGPHRDPRRARAAGVNIVPTTTGAAKAIGLVLPN
                     LDGRLSGDSIRVPVPVGSIVELNTTVARDVTREDVLTAYREAAEGRLAGVLEYSEDPLV
                     SSDITGNPASSIFDSALTRVDGRHVKVVAWYDNEWGFSNRVIDTLELLAAG*"
     CDS             complement(1051..1874)
                     /protein_domains="PF04672"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951793"
                     /pseudo=False
                     /translation="MSNTHAARGIDTSRPHSARMYDYYLGGKDHFDIDKQAAETVAAAY
                     PGIFVCARENRAFMHRATRVLAREHGIRQWLDIGTGIPTEPNLHQVAQSVVPEARVVYA
                     DNDPLVLKYAERLMRSTPQGRTTYIEADVNDPESLLNAPELSDVLDLDRPVALSLNALM
                     HFVTDAQDPYGIVGRLLAALPSGSALALSHCTPDFDPATWQKVTDIYTGAGTPVRFRSQ
                     KDVVRFFDGLDLLDPGVTIGHRWRPDVSDGSDPAEAPTDAEVSLWTGVGIKP*"
     CDS             complement(1972..2222)
                     /protein_domains="PF04149"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951794"
                     /pseudo=False
                     /translation="MTIADGSVYNGMPACDLGEQGWESPWSGPNGGQCVQTKQLADGRV
                     ALRQSTDPTGPALIYTPEEIAAFVQGIKRGLADHLTAH*"
     CDS             complement(2220..3091)
                     /protein_domains="PF13560"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951795"
                     /pseudo=False
                     /translation="VSDARASAGTSAPTVLRMILGRRLQERRLGAGVSLDDAAKALRVT
                     SLTIRRLEKAEVGLKPLYVEKLLQTYGAGQQEIDEFVELAERANEPGWWHAYRDVVPSW
                     FTAYVSLESGAKTLRTYEPQYVTGLLQTYGYARAVLRGGFPNDGDEELERRVDLRLRRQ
                     SLLEKPDAPTLWVVMEEAVLHRVAGGPEIMREQIDRLLEVSELDHVSVDIVPFSAGAHV
                     GACAPFTYFRFEEPELPDVVYSEILSASVYLDQRADVAAHLEAHNRMSLLTSSADSRTL
                     LHRMRKEYS*"
     CDS             3415..3860
                     /protein_domains="PF13581"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951796"
                     /pseudo=False
                     /translation="VSPHTTSSPQLLDAVSPERTHWIELPALRSSVQVARRSVNARMTA
                     WGLPAEICADAVLLVSELVTNAVCHTRSVQVLCGIGRVTDDCLRLEVHDHDITVGRLPR
                     CEAGPEDESGRGLFLVQEIARTWGFARSRLTGGNAVWATLTTGG*"
     CDS             complement(3928..5531)
                     /protein_domains="PF01425"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951797"
                     /pseudo=False
                     /translation="MDRIAPSRRTLLALGTATAASPWLGETPARATDGHPDAPTDLDEL
                     GITDLRRRMADGRLTAERLTRYYLERIERVDPLLHSVIEVNPDALAEARRLDAEGDRRR
                     PLHGMPVLLKDLVETADRMHTTAGSLALEGLRPARDATVAARLRAAGAVVLGKTNLSEW
                     AGGMSLTHHAGWSARGGQTRNPYKLDRSPNESSSGTAVAAAANLCVAGIGTETNGSIID
                     PASANCVVGVKPTVGLVGRGGVIPGVPSQDSVGPIARTVRDAAILLGTLVGLDDRDPAT
                     TASRGHFHRDYTRFLDADGLRGARIGVPRSVYFGYSHHADEIAERAVAVLRAAGATVVD
                     PADIPTAEQLEDLPSSMVVQAYEIKRGLNAYLASAPGDHPRSLAELIAFNRAHADRELR
                     HVRQDGLEAVHELDFSESEYRAALATNHRLSRAEGIDAVLRRHRLDALVTPTGGPPAKI
                     DLVRGDSYTGGASTPAALAGYPAISVPAGFAFGLPVGVTFMGTAWSEPTLLRLAYAYEQ
                     ASRVRRPPTYRPADVGF*"
     CDS             complement(5637..8695)
                     /protein_domains="PF01074"
                     /protein_domains="PF07748"
                     /protein_domains="PF09261"
                     /protein_domains="PF17677"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951798"
                     /pseudo=False
                     /translation="MHNDRDVTEQRLARVLNERIRPAAHARSVPLDVQVWHVSGEPVPV
                     SEGLAAPYRPARVGDRWGPAWSTSWFKVTGTVPADWAGETVEAVLDLGFATHSAGFSAE
                     GLVYRPDGTAVKALNPRNIWVPVAEQAVGGEEFTVFVEAAANPVVMHTAPDELTFGPTA
                     VGGPAPWLGDPAADPGEPLYRLRRLDLAVLDRDVHELVQDLEVLGQLMPELAAEDPRRW
                     QILRAVERALDTVDLQDVGGSAAAARAALAPVLAAPAQASAHRISAVGHAHIDTAWLWP
                     LRETVRKVARTVSNVTHLMDDHPEFKFVMSQAQQLAWLKEHRPEVYARAQEKAKTGQFL
                     PSGSLWVEPDTNISGGEALVRQFVHGKRFYLEEFGVETEEMWLPDTFGYNAALPQLMKL
                     AGVRWFLTQKISWNTTNKFPHHTFWWEGIDGTRIFSHFPPVDSYNGDLSGDQVAHSVRN
                     FQDKSGSNSSLIPFGYGDGGGGPTREMLARAARLKDLEGSPRIEIEGPADFFRRAHDEY
                     EANGGAPVWSGELYLEFHRGTLTSQLATKQGNRRSEHLLREAELWAATAAVRHGHAYPY
                     VALDRLWKTVLLHQFHDILPGTSIAWVHREAEETYAAVARELEELIGEAQRTLAGDPGG
                     TVVFNAAPHPRGGVAALGAGPRAVEAAVVPPVPDGDGFVLDNGLVRVVVDGRGLITSAY
                     DHSAGREALAPGAVGNLLQLHQDFPNQWDAWDVDAFYRNTVRDLTEAESVTATGTGVRV
                     VRVFGASRIEQTLTLPSGSRGLVIDTVVDWHEREKLLKAAFPLDVRASHSTAEIPFGHV
                     ERPTHTNTSWDAAKFEVCAHRFLHVGEPDWGAAVVNDSSYGHDITRDVRSDGGTTTTVR
                     LSLLRAARFPDPDQDQGTHRLGYALVIGADVADATREGYRFNLPERALPGSATVAPLVS
                     VDLEGVIVEAVKLADDRGGDIVVRLYESRGTRARATLTTGFPLASATATDLLERPVDDP
                     ASHRHTDTGVELALRPFQILTLRLRPAAGS*"
     CDS             complement(8752..9644)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951799"
                     /pseudo=False
                     /translation="MAAVATPPAATAPRKVPPPVRPRRRRVRPGRVAINLVLLAVSVLY
                     VLPLLWMVLASVSDTNSFRLQWPSSLTFDNFDAVLDVDTTYRPMLNSLLLCGFGTAVTV
                     VTSVLCAYPLSRYRSRVRRPFLYTILFSTGLPITAVMIPVYSMFVQVNLIDSMPGTTLF
                     LAASALPFGIWLMKNFMDGVPVVLEEAARIDGANTMQVLWRVVLPLMRPGVVVVTIFTF
                     IGMWGNFFVPFILLLSPEKLPASVSVFTFLSAHDQTQYGQLSAFSLIYSLPVVLLYILL
                     ARKLGGGFALGGALKG*"
     CDS             complement(9645..10570)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951800"
                     /pseudo=False
                     /translation="VTALAPAPHGTGPRRSRGAPAPAVRTLLRGLPTLPAVVLLAVFLA
                     GPIAYCVYYAFTDMQLTGASGTSFVGIDNFTRAFEDGDFLNSVWLTLVFVVGSAVIGQN
                     TLGLALAVLMEKATKPVRSLVNGVVIAAWVLPEVVAGYLMYAFFYDQGSLNSLLDAVGL
                     PQQNWLYTMPILAVCLANVWRGTAFSMMVFTAAVNDVPRELLEAAEMDGAGPWQRLWRV
                     VLPVIRPSILTNLMLITLQTLSVFGLIYTMTRGGPGNKSETLPIFMYQQAFQNSLIGYG
                     TAIALVLLVVGALFSVVYIRLLKLEDD*"
     CDS             complement(10568..11946)
                     /protein_domains="PF01547"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951801"
                     /pseudo=False
                     /translation="VRVRLVTAAAFTAATALAVTGCGSGSSGSSAKSIKVVYWQNLDST
                     NKLQATYLASMVKQFTQANPGTKVNLVPVTASENDYYTKIQLMMRSPATAPDLVYEDTA
                     LINSDIAGGYLKPLDAYTAKWADWAQYADAAKGAVTGAADGKVYGVPDNTDTRGIWYNK
                     QLFQKAGIQVPWQPKTWADVLDAAKTVKAKLPDVTPLNLYTGTAGGEASSMQGFEMLLY
                     GTPAGDKSLYDTSRKKWVVGSKGFKDALDFVHTVYSQGLGPAKEQALGANFGTTVGTEL
                     LPQGKLAMDIDGSWMPNNWSSSAAKPWTEWQSVMGTAAMPTQSGQAPGRTSMSGGWAWS
                     VPAKAKNPDLAWKFLSTTLQTKANSATWNARNATIAVRKDVAADPTYLKAVPTNKFFTE
                     LVADTHYRPGLPAYNQVSTAIQKAMESVTTGQASVEKAAETFDNDVKAAVGDDKTVEGT
                     S*"
     CDS             complement(12083..12201)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MSVTWSPHVGPTPVGGPARGTPVAEVYILEALTSSIKWI"
     CDS             12209..13446
                     /protein_domains="PF00480"
                     /protein_domains="PF12802"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951802"
                     /pseudo=False
                     /translation="MLSGTNLPRVGGYNQAVVLDAIRTTGQVSRVELAALTGLTNQTVS
                     NVVRKLLDAGLVAESGQAPSSGGKRRTLLSIRADGAFAVGVHLDPEAAVIVVADLAGDV
                     VGGRRLRLTDPGDPEDVVERVARAAGRLVERSGVDRSRLLGLGVAAPGPLDGTSGAVVS
                     PPNFPGWGRVPLADMFATATGLPVALDNDATAAAIGERWIGGADRAGSFLFVYFGTGIG
                     AGIVLNNTVLHGDSGNAGEFGHMAVEPGERVCHCGATDCLGPYVSPPAIIDDLLRLHGR
                     AAADRIGLTGTPDTVHHDWKALRRAARAGDPDACDVVRRAARRIGEAARGAASLLDVSR
                     VVLGGEALRGIEPILREEIDAAVNRTSVARAIRAVAVEQSVIGDTVGAVGAASLVLHGN
                     YAPGWRMLTDVSG*"
     CDS             complement(13459..14309)
                     /protein_domains="PF00005"
                     /protein_domains="TIGR01166"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951803"
                     /pseudo=False
                     /translation="MSEPVLVALRGASFAYEDGPAVLSGLDFEVREGRALALLGRNGSG
                     KTTLMRLLSGGLRPRSGELTVEGRPVRHDRKGLTRLRTTVQLVVQDPDDQLFAASVGQD
                     VSFGPLNLGLPDAEVRARVGEALAALDITALADRPTHLLSYGQRKRTAIAGAVAMRPRV
                     LILDEPTAGLDPDGQERLLSTLDDLCGTGTTVVMATHDVDLALRWADDAALLTPSGAHI
                     GPAATMLARTDLLRQAGLRLPWGVAAARLLREQGLLDATAPGPRTPDELAALVAPPLGA
                     EG*"
     CDS             complement(14307..15055)
                     /protein_domains="PF02361"
                     /protein_domains="TIGR02454"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951804"
                     /pseudo=False
                     /translation="VLPIDAAAHSSRWRHRHPVDKAVLGLGLTLLAISLPPWPGAALVL
                     VTALVVLLGPAGVPARRLWRAYRVPLGFCATGAITLLVQVGGPDGFVSPAPDGPVRAGE
                     LLLRTSAASLGVLLFAFTTPMSDLLPRLVKAGVPAPVVDVALVTYRMSFLLLDSMRRIR
                     EAQAARLGHTNRAAEWRSLAGLGATAFVRAFDRAARLQDGLAGRGYDGTLRVLVPEAHV
                     SARFTAAAVVLLATVAALTFVLERPLR*"
     CDS             complement(15062..15438)
                     /protein_domains="PF02553"
                     /protein_domains="TIGR01165"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951805"
                     /pseudo=False
                     /translation="MSRNAKINALLVLVVVALAVLPLALGLGDHKKEPFTGADAEAETA
                     ITEIEPDYEPWFSPLYEPPSGEIESALFALQAALGTGVLTYYFGLHRGRRQGEQRALAR
                     LEAQGTAAPERASDESSAERT*"
     CDS             complement(15436..16136)
                     /protein_domains="PF01891"
                     /protein_domains="TIGR00123"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1951806"
                     /pseudo=False
                     /translation="MHIAEGFLPPAHAIAWSVASAPFVVHGVRSLTREVKEHPESTLLL
                     GASGAFTFVLSALKLPSVTGSCSHPTGTGLGAILFRPPIMAVLGTITLLFQALLLAHGG
                     LTTLGANVFSMAIVGPWAGYALYRLLRRYDVPLMVAVFFGAFAADLSTYCVTSVQLALA
                     FPDPSSGFLGALGKFGSIFAVTQIPLAVSEGLLTVLVMRLLSQSSKGELVRLGVLTAGG
                     RSAAGTEAVAR*"
ORIGIN
        1 atgactcgca tcgccatcaa cggattcggc cgcatcggac gcaacgtgct gcgcgccctg
       61 ctcgaacgcg acagcaccct cgaagtcgtc gcggtcaacg acctcacgga gcccgccacc
      121 ctcgcccgac tgctggccta cgacagcacg gccggacggc tcggtcgtcc ggtgaccgtc
      181 gacggcaaca ccctcgtcgt ggacggccgc cgtatcaccg tgctcgccga gcgcgagccg
      241 gcgcagctgc cgtgggccga cctcggtgtc gacctcgtcc tggaggccac cggccgcttc
      301 acctcggcca aggccgcccg cgcccacctc gacgcgggcg cgcggaaggt gctggtcagc
      361 gcgccgtcgg acggtgccga cgtcacgctg gcgtacgggg tcaacaccga cgcctacgac
      421 ccgcaggtgc acacgatcgt ctcgaacgcc tcctgcacga ccaacgcgct cgccccgctg
      481 gccgcggtcc tcgacgaact cgccgggatc gagcacgggt tcatgacgac cgtgcacgcc
      541 tacacgcagg aacagaacct tcaggacggc ccgcaccgcg acccccggcg ggcccgggcc
      601 gccggggtga acatcgtgcc gaccacgacc ggagccgcca aggcgatcgg cctggtgctg
      661 ccgaacctgg acggcaggct gtcgggcgac tccatccggg tgccggtccc ggtgggttcg
      721 atcgtcgagc tcaacacgac cgtcgcccgt gacgtgaccc gcgaggacgt cctgacggcg
      781 taccgggagg cggccgaggg gcggctcgcg ggcgtcctgg agtactcgga ggacccgctg
      841 gtctcttccg acatcaccgg caacccggcc tcgtcgatct tcgactcggc cctcacccgc
      901 gtcgacggcc gccatgtgaa ggtggtcgcc tggtacgaca acgagtgggg cttctcgaac
      961 cgggtgatcg acaccctcga actgctcgcg gccggctgac ccgtgagaaa gggggctccg
     1021 gtcgcgcggc gaccggagtc cctgccttgt cagggcttga tgccgacccc ggtccacagg
     1081 ctgacctcgg cgtccgtcgg cgcctcggcg ggatccgagc cgtcggagac gtcggggcgc
     1141 cagcggtggc cgatggtgac gcccgggtcg agcaggtcga gcccgtcgaa gaagcgtacg
     1201 acgtccttct ggctgcggaa ccgcaccgga gtccccgcgc cggtgtagat gtcggtgacc
     1261 ttctgccagg tggccgggtc gaagtcgggt gtgcagtggc tgagggccag cgcgctgccc
     1321 gaggggagcg cggcgagcag tcggccgacg atgccgtagg ggtcctgcgc gtcggtgacg
     1381 aagtgcatga gcgcgttgag cgacagggcc accggccggt ccaggtccag gacgtcggac
     1441 agctcgggcg cgttgagcag cgactccggg tcgttgacgt cggcctcgat gtaggtggtg
     1501 cggccctgcg gggtgctgcg catgaggcgc tcggcgtact tcaggacgag cgggtcgttg
     1561 tcggcgtaca ccacgcgcgc ctcgggtacg acactctggg cgacctggtg caggttcggc
     1621 tcggtgggga tgccggtgcc gatgtcgagc cactggcgga tgccgtgctc gcgggcgagg
     1681 acgcgggtgg cgcggtgcat gaaggcccgg ttctcgcggg cgcacacgaa gatgccgggg
     1741 taggcggcgg cgaccgtctc ggcggcctgc ttgtcgatgt cgaagtggtc cttgccgccg
     1801 aggtagtagt cgtacatgcg ggcggagtgc ggcctgctgg tgtcgatgcc ccgtgcggcg
     1861 tgggtgttgc tcatcctgtc cccttcggtg gtgtgcgcgg tgtgcgcggt gtgccgggcg
     1921 ggtcgcggcc ggggccggct cggatcctcc ccgcgggtgg ttcgctcgcc ctagtgggcc
     1981 gtcaggtgat cggcgagacc tctcttgatc ccctggacga atgcggcgat ctcctcgggt
     2041 gtgtagatca gcgcgggacc ggtgggatcg gtcgactgcc gcagggcgac gcggccgtcg
     2101 gcgagttgct tggtctgcac gcactggccc ccgttggggc cgctccacgg gctctcccag
     2161 ccctgctcgc cgaggtcaca ggcgggcatc ccgttgtaca cactgccgtc ggcgatggtc
     2221 atgagtactc cttgcgcatg cggtgcagca gagtcctgct gtccgcggag gaggtcagaa
     2281 gggacatccg gttgtgcgcc tccagatggg ctgcgacatc ggcgcgctgg tccaggtaga
     2341 cggaggcgga caggatttcg ctgtagacga cgtcgggcag ctccggttcc tcgaaccgga
     2401 agtaggtgaa gggcgcgcac gcgccgacgt gcgcgccggc cgagaacggc acgatgtcga
     2461 cgctgacgtg gtccagctcc gagacctcca ggagccggtc gatctgctcc cgcatgatct
     2521 ccggaccgcc cgcgacccgg tgcaggacgg cctcctccat caccacccac agggtggggg
     2581 cgtcgggctt ctccagcagg ctctggcggc gcagccgcag atcgacccgc cgctccagct
     2641 cctcgtcgcc gtcgttggga aagccgccgc gtaacacagc gcgcgcatag ccgtacgtct
     2701 gcaacagccc ggtgacgtac tgcggttcat aggtgcgaag ggtcttggcc ccgctctcca
     2761 ggctcacgta ggcggtgaac cagctgggca ccacatcacg gtaggcgtgc caccagccgg
     2821 gctcgttggc ccgctcggcg agctcgacga actcgtcgat ctcctgctgc ccggccccgt
     2881 aggtctggag cagcttctcc acgtacaggg gcttgaggcc gacctccgcc ttctccaggc
     2941 ggcgaatggt caacgacgtc acacgcaggg cctttgccgc gtcgtcgagc gacacgcccg
     3001 cgccgagccg ccgctcctgg agccgacggc ccaggatcat ccgcaggacg gtcggtgcgc
     3061 tggttcccgc actcgcccga gcgtcactca ctggagccac ctcctgatgc cctgtcaccg
     3121 gcgccggtcc ggcggagagt tgaagatgcc gccaaacgga tatcgtcttg ctgaaattat
     3181 cagggagtcg gttgcagtgt gaactcagct gcgagcatag ttacttgtgc aagcggttcc
     3241 ttcggacgcg aaggcatcgt ggtcaactat cgctctacta cgcagagttg acatgcgccg
     3301 acgctccgaa tccgcgcggc cccacgccgg gaacaacccc ctctcccgac gggccggctg
     3361 ctcgccctcc tcgccccctc ccccctgcgc tcctcctgac ggaaggcaca agcgtgtccc
     3421 cccacacgac ttcctccccc cagctcttag acgccgtgag cccggagcgc acgcactgga
     3481 tcgagctccc cgcgctccgc tccagcgtcc aggtcgcccg ccgttcggtg aacgcccgca
     3541 tgaccgcctg gggactgccc gccgagatct gcgcggacgc ggtgctcctg gtgtcggaac
     3601 tggtcaccaa cgcggtgtgc cacacgcgca gtgtgcaggt cctgtgcggc atcggacgcg
     3661 tgacggacga ctgtctccgc ctggaggtgc acgaccacga catcacggtc ggcaggctgc
     3721 cccgctgcga ggcggggccc gaggacgaga gcggacgcgg actgttcctc gtgcaggaga
     3781 tcgcccgcac ctggggattc gcccgttccc ggctcacggg cggcaacgcg gtgtgggcga
     3841 ccttgacgac cggcggctga gcgggcgcgt tcgagcgggc gtgtctgcgc gggcggcgag
     3901 ccgcccgcgc ggaagggccg cccgggtcag aagccgacgt cggcgggacg gtacgtggga
     3961 ggccgacgga cacgactggc ctgctcgtag gcgtacgcga ggcggagcag ggtcggctcg
     4021 ctccatgccg tgcccatgaa ggtcaccccg acgggcagac cgaacgcgaa accggccggg
     4081 acgctgatcg cgggatatcc ggccagcgcg gcgggcgtcg acgcgccacc ggtgtagctg
     4141 tccccgcgga ccaggtcgat cttggccggc ggtccgcccg tcggcgtgac gagtgcgtcc
     4201 aggcggtggc ggcgcagcac cgcgtcgatg ccctcggcgc gtgagagccg gtggttggtg
     4261 gcgagggccg cacggtactc gctctcgctg aagtccagct cgtgcaccgc ctccaggccg
     4321 tcctgccgga catggcggag ctcgcggtcg gcgtgcgcgc ggttgaaggc gatcagctcc
     4381 gccagactgc gcggatggtc gccgggggcg ctcgccaggt aggcgttcag cccgcgcttg
     4441 atttcgtaag cctgtacgac catcgagctg ggcagatcct ccaactgctc ggcggtcggg
     4501 atgtcggcag ggtcgaccac ggtcgcgccg gccgcgcgca gcacggcgac cgcccgctcg
     4561 gcgatctcgt cggcgtggtg gctgtagccg aagtacaccg agcgcggcac gccgatacgg
     4621 gccccgcgca ggccgtcggc gtccaggaag cgggtgtagt cgcggtggaa gtgcccgcgg
     4681 ctcgccgtgg tcgccgggtc gcggtcgtcg agcccgacca gggtgccgag gaggatcgcg
     4741 gcgtcgcgga ccgtgcgggc gatcggtccg acactgtcct ggctcggcac accagggatc
     4801 accccgccgc gcccgaccag cccgacggtc ggcttcacgc cgacgacaca gttcgccgag
     4861 gccgggtcga tgatcgagcc gttggtctcg gtcccgatac cggcgacaca caggttggcc
     4921 gcggcggcca ccgcggtgcc ggagctggac tcgttcggcg accggtccag cttgtacgga
     4981 ttacgggtct gcccgccgcg ggcgctccac ccggcgtgat gggtgagcga catcccgccc
     5041 gcccactcgc tcaggttggt cttgccgagg acgaccgcgc cggccgcccg cagccgggcg
     5101 gcgaccgtgg cgtcccgggc cggccgcagg ccctccagcg cgagtgatcc ggccgtggtg
     5161 tgcatccggt ccgcggtctc caccaggtcc ttgagcagca cgggcatacc gtgcagcggc
     5221 cggcgccggt ccccttcggc gtcgaggcgc cgggcctcgg cgagcgcgtc ggggttgacc
     5281 tcgatcaccg agtgcagcag cgggtcgacg cgctcgatgc gctccaggta gtagcgggtg
     5341 agccgttcgg cggtcagccg tccgtcggcc atccgccgcc tgaggtcggt gatgccgagt
     5401 tcgtcgaggt cggtgggcgc gtcggggtgt ccgtccgtgg cacgtgcggg ggtttcgccg
     5461 agccagggcg aggccgccgt ggcggtgccc agcgcgagca gggtgcgacg tgaaggggcg
     5521 atccggtcca tggccgcaac gctaggggcg tggccggccg atctcgctcc ggccggcccc
     5581 cggttccaac aggaggagca ccccctgccc caccgggggc cagcaggacc cgacgtcagc
     5641 tcccggcggc gggccgcagc cgcaacgtga ggatctggaa aggacgcagg gccaactcca
     5701 cgccggtatc ggtgtgccga tgggacgcgg ggtcgtcgac cgggcgctcc agcaggtccg
     5761 tcgcggtggc cgaggccaac gggaacccgg tggtgagggt ggcccgggcc cgggtgccgc
     5821 gggactcgta gagacggacg acgatgtcgc cgccgcggtc gtcggcgagt ttcaccgctt
     5881 ccacgatcac cccctcgagg tcgaccgaga ccagcggggc gaccgtcgcg ctgcccggca
     5941 gcgcccgctc gggcaggttg aagcggtagc cctcacgggt cgcgtcggcg acgtcggcgc
     6001 cgatcacgag cgcgtagccg agccggtggg tgccctggtc ctggtcgggg tcggggaagc
     6061 gggccgcgcg cagcagggag aggcggaccg tggtcgtcgt cccgccgtcg gaccggacgt
     6121 cacgcgtgat gtcgtgcccg taggaggagt cgttgaccac ggcggcaccc cagtcgggct
     6181 cgccgacgtg caggaaccgg tgggcgcaca cctcgaactt ggcagcgtcc cagctggtgt
     6241 tggtgtgcgt gggccgctcg acgtgcccga aggggatctc ggccgtcgag tgggaggccc
     6301 ggacatccag cgggaaggcg gccttgagca gcttctcccg ctcgtgccag tcgacgaccg
     6361 tgtcgatcac gagcccgcgg gaaccggacg gcagggtcag ggtctgctcg atccgcgacg
     6421 cgccgaagac acggaccacg cggacaccgg tgccggtcgc ggtgacggac tccgcctcgg
     6481 tgaggtcccg gacggtgttg cggtagaacg cgtcgacgtc ccaggcgtcc cactggttgg
     6541 ggaagtcctg gtgcagctgg agcaggttgc cgaccgcgcc gggtgccagg gcctcgcggc
     6601 cggcgctgtg gtcgtaggcg gaggtgatca gaccgcgacc gtccacgacg acccgcacca
     6661 ggccgttgtc gaggacgaac ccgtccccgt cgggcaccgg tggcacaaca gcggcctcca
     6721 cggcgcgcgg gcccgcgccg agcgccgcca caccgccgcg ggggtgcggc gcggcgttga
     6781 agacgaccgt gccgccggga tcgccggcca gcgtccgctg ggcctcgccg atcagctcct
     6841 ccagttcccg ggcgacggcc gcgtacgtct cctccgcctc gcggtgcacc caggcgatcg
     6901 acgtaccggg caggatgtcg tggaactggt gcagcagcac cgtcttccac agccggtcca
     6961 gggcgacgta cggataggcg tgcccgtgcc gtacggcggc cgtggccgcc cacaactcgg
     7021 cctcgcgcag caggtgttcg ctgcgccggt tgccctgctt ggtggcgagc tggctggtga
     7081 gggtgccgcg gtggaactcc aggtacagct cgccggacca caccggggcg ccgccgttcg
     7141 cctcgtactc gtcgtgcgcg cgccggaaga agtcggccgg gccctcgatc tcgatgcggg
     7201 gcgagccctc caggtccttc aggcgggcgg cgcgggcgag catctcgcgg gtggggccac
     7261 cgcctccgtc gccgtagccg aacgggatca gcgagctgtt cgagccgctc ttgtcctgga
     7321 agttgcggac gctgtgggcg acctggtcgc cggagaggtc gccgttgtag ctgtcgacgg
     7381 gcgggaagtg gctgaagatc cgggtgccgt cgatgccctc ccaccagaag gtgtggtgcg
     7441 ggaacttgtt ggtggtgttc caggagatct tctgcgtcag gaaccagcgc accccggcca
     7501 gcttcatcag ctgcggcagg gccgcgttgt aaccgaaggt gtccggcagc cacatctcct
     7561 cggtctcgac gccgaactcc tccaggtaga accgcttgcc gtgcacgaac tggcgcacca
     7621 gcgcctcacc gccggagatg ttggtgtccg gctccaccca caggctgcca ctcggcagga
     7681 actgccccgt cttcgccttc tcctgcgccc gcgcgtacac ctccggccgg tgctccttca
     7741 gccaggcgag ctgctgcgcc tgggacatca cgaacttgaa ctccgggtgg tcgtccatga
     7801 gatgggtgac gttggagacc gtccgggcca ccttgcggac ggtctcgcgc agcggccaca
     7861 gccacgcggt gtcgatgtgc gcgtgcccca ccgccgagat ccggtgcgcg ctcgcctgcg
     7921 cgggtgccgc cagcaccggg gcgagcgcgg cccgcgccgc cgccgcgctg ccgccgacgt
     7981 cctggaggtc caccgtgtcc agggcgcgct cgaccgcccg caggatctgc cagcggcgcg
     8041 ggtcctcggc ggccagctcg ggcatcagct ggcccaacac ctccagatcc tggacgagtt
     8101 catgcacgtc ccggtcgagg acggcgaggt ccaggcgccg cagccggtac aggggctcgc
     8161 ccgggtcggc ggccgggtcg cccagccagg gggcgggacc gcccaccgcg gtgggtccga
     8221 aggtgagttc gtcgggggcg gtgtgcatga cgaccggatt ggcggcggcc tcgacgaaga
     8281 ccgtgaactc ctcgccgccc accgcctgtt cggccaccgg cacccagatg ttgcgcggat
     8341 tgagcgcctt cacggcggtg ccgtcgggcc ggtagaccag cccctcggcg gagaagccgg
     8401 cggagtgggt ggcgaaaccg agatccagga cggcctcgac cgtctccccg gcccagtcgg
     8461 cggggacggt gccggtgacc ttgaaccagc tggtggacca ggcgggcccc caccggtccc
     8521 cgacccgggc cggccggtag ggggcggcca ggccctcgct caccggcacc ggctcgccgg
     8581 agacgtgcca gacctgcacg tcgaggggga cggaccgggc gtgggcggcg ggccgtatgc
     8641 gctcgttcag aacgcgggcg agccgctgtt cggtgacgtc gcggtcgttg tgcatgaggt
     8701 gttcttctcc gtagaggtgg gggaacctgc ccttggtccc ggcagggaag tcagcccttg
     8761 agcgcgccgc cgagcgcgaa accgccgccg agcttgcggg ccagcaggat gtagagcagg
     8821 acgacgggca gtgagtagat gagggagaac gccgacaact gcccgtactg cgtctggtcg
     8881 tgggcgctga ggaaggtgaa cacgctgacg gacgcgggga gtttctccgg ggacagcagc
     8941 aggatgaagg ggacgaagaa gttcccccac atgccgatga acgtgaagat ggtgaccacg
     9001 acgacaccgg gccgcatcaa cggcagcacc acccgccaca gcacctgcat cgtgttcgcg
     9061 ccgtcgatcc gggcggcctc ctccaggacg accggtacgc cgtccatgaa gttcttcatc
     9121 agccagatcc cgaacggcag cgcggacgcg gccaggaaca gcgtcgtgcc gggcatcgag
     9181 tcgatcaggt tcacctgcac gaacatgctg tagaccggga tcatcaccgc ggtgatgggc
     9241 agaccggtgg agaacaggat cgtgtacagg aacggccgcc gcacccggga gcggtagcgc
     9301 gagagcggat aggcgcacag caccgacgtc accacggtca ccgccgtacc gaagccgcac
     9361 agcaacaggc tgttgagcat cggccggtag gtggtgtcga cgtcgaggac cgcgtcgaag
     9421 ttgtcgaacg tcagcgacga gggccactgg agccggaagc tgttggtgtc gctcaccgac
     9481 gcgaggacca tccacagcaa cggcaggacg tacagcaccg acacggcgag caggaccagg
     9541 ttgatcgcga cgcgtcccgg gcgcacccgg cgccggcgcg ggcggacggg cggcggcacc
     9601 ttccgtgggg cggtcgcggc gggcggggtg gcgacggcgg ccatcagtcg tcctccagtt
     9661 tcagcagccg gatgtacacg acggagaaca gcgcgccgac caccagcagc accagggcga
     9721 tcgccgtgcc gtacccgatc aggctgttct ggaaggcctg ttggtacatg aagatcggaa
     9781 gcgtctcgct cttgttgccc ggtccgcccc gggtcatggt gtagatcagc ccgaagacgg
     9841 agagcgtctg gagcgtgatc agcatcaggt tggtcaggat cgacggcctg atcactggca
     9901 gcacgacccg ccacagccgt tgccagggcc cggcgccgtc catctcggcg gcctccagca
     9961 gctcccgggg cacgtcgttg acggcggctg tgaagaccat catcgaaaag gcggtgccgc
    10021 gccacacgtt ggccaggcac accgccagga tcggcatcgt gtacagccag ttctgctgcg
    10081 gcagaccgac ggcgtccagg agcgagttga gcgagccctg gtcgtagaag aaggcgtaca
    10141 tcagatagcc ggcgaccact tcgggcagca cccacgcggc gatgaccacc ccgttgacca
    10201 gggagcgcac cggcttggtg gccttctcca tcaggacggc cagcgcgagg ccgagcgtgt
    10261 tctgcccgat caccgcggag ccgaccacga acaccagggt cagccacacc gagttgagga
    10321 agtcgccgtc ctcgaaggca cgggtgaagt tgtcgatccc gacgaaggag gtgccggagg
    10381 ccccggtgag ctgcatgtcc gtgaacgcgt agtacacgca gtacgcgatc ggaccggcca
    10441 ggaagacggc cagcagcacc acggccggca gcgtcggcag accgcgcagc agggtacgga
    10501 cggcaggagc gggcgccccg cgggaccggc gcgggccggt cccgtgaggc gccggagcga
    10561 gggcggtcac gaagtgccct ccaccgtctt gtcgtcgccc accgccgcct tgacatcgtt
    10621 atcaaatgtc tcggccgcct tctcgaccga ggcctggccg gtcgtcacgg actccatcgc
    10681 cttctggatg gcggtcgaca cctggttgta ggcgggcagt cccggccggt agtgggtgtc
    10741 ggcgaccagt tcggtgaaga acttgttggt cggcaccgcc ttcagatacg tcgggtcggc
    10801 ggccacgtcc ttgcgcaccg cgatcgtggc gttgcgcgcg ttccaggtcg cggagttggc
    10861 cttcgtctgg agcgtggtcg acaggaactt ccacgccagg tccgggttct tggccttggc
    10921 cgggaccgac caggcccagc cgcccgacat gctggtacgg ccgggagcct gcccgctctg
    10981 cgtgggcatg gccgcggtgc ccatcaccga ctgccactcg gtccacggct tggccgccga
    11041 cgagctccag ttgttgggca tccaggagcc gtcgatgtcc atcgccagct tgccctgggg
    11101 gaggagctcg gtgcccaccg tggtgccgaa gttggcgccc agcgcctgct ccttggccgg
    11161 gccgagcccc tggctgtaga cggtgtgcac gaagtccagc gcgtccttga agcccttgct
    11221 gcccacgacc cacttcttcc gcgaggtgtc gtagagggac ttgtcgccgg ccggggtgcc
    11281 gtacagcagc atctcgaagc cctgcatgga ggacgcctcg ccacccgccg tgcccgtgta
    11341 gaggttgagc ggggtgacgt cgggcagctt cgccttgacc gtcttcgccg cgtcgaggac
    11401 gtccgcccag gtcttcggct gccagggcac ctggatcccg gccttctgga agagctgctt
    11461 gttgtaccag atcccgcggg tgtcggtgtt gtccggtacg ccgtagacct tgccgtcggc
    11521 ggcgccggtc accgcgccct tggccgcgtc ggcgtactgc gcccagtcgg cccacttcgc
    11581 ggtgtaggcg tcgaggggct tgagatagcc gcccgcgatg tcggagttga tgagggcggt
    11641 gtcctcgtag accaggtcgg gcgccgtcgc gggggagcgc atcatgagct ggatcttggt
    11701 gtagtagtcg ttctcggagg cggtcaccgg caccaggttc accttggtgc ccgggttggc
    11761 ctgggtgaac tgcttcacca tcgaggcgag gtaagtggcc tgcagcttgt tggtgctgtc
    11821 caggttctgc cagtagacga ccttgatcga cttggccgag ctgcctgacg agcccgagcc
    11881 gcagccggtg acggccaggg cggtggcggc ggtgaaggcc gcggcggtga cgagtctgac
    11941 gcgcacagtg gttcctccgg gacgtgaaac ctgtgggaga gccgcgagta cttttggccg
    12001 ggaaaccagc ccggacggca ccccacgctt ggcgccaccc tgcgctgact ggcctcgatg
    12061 gccggatttt gtgggcgtca gctaaatcca tttgatggat gaagtcaatg cttccagtat
    12121 gtaaacttcc gccaccggag tgcctctcgc aggccctccg acgggggtgg ggccgacgtg
    12181 aggggaccag gtgaccgaca ggtgacgatg ctcagcggga cgaacctgcc gcgggtcggc
    12241 ggctacaacc aggccgtcgt cctggacgcc atccgcacca cgggacaagt gagccgggtc
    12301 gagctggccg cactcaccgg cctgaccaac cagaccgtct ccaacgtcgt ccgcaaactc
    12361 ctcgacgccg gcctggtggc cgaatccggc caggccccgt ccagcggcgg caagcgccgc
    12421 accctgctgt cgatacgggc cgacggcgcc ttcgcggtcg gcgtccacct cgaccccgag
    12481 gccgcggtca tcgtggtcgc cgacctggcg ggagacgtcg tgggaggccg ccggctgcgg
    12541 ctgaccgatc ccggcgaccc cgaggacgtc gtggagcggg tcgcgcgcgc cgccgggcgg
    12601 ctcgtcgagc gtagcggtgt cgaccgctcc cgcctgctcg gcctcggcgt cgccgcgccc
    12661 ggaccgctcg acggcacctc cggagccgtg gtgtccccgc cgaacttccc cggctgggga
    12721 cgggtgcccc tggcggacat gttcgccacg gccaccggcc tgcccgtcgc tctcgacaac
    12781 gacgccaccg ccgccgccat cggggagcgc tggatcggcg gcgccgaccg cgccggcagc
    12841 ttcctcttcg tctacttcgg caccggcatc ggagccggga tcgtcctcaa caacaccgtg
    12901 ctgcacggcg attcgggcaa cgccggcgag ttcggccaca tggcggtcga gccaggagag
    12961 cgcgtctgcc actgcggcgc caccgactgc ctcggcccgt acgtcagccc gcccgcgatc
    13021 atcgacgacc tgctgcgcct gcacggccgc gccgccgccg accgcatagg cctgaccggc
    13081 acccccgaca ccgtccacca cgactggaag gccctgcgcc gcgccgcccg cgccggtgat
    13141 ccggacgcct gcgacgtcgt acgccgggcc gcgcgccgga tcggcgaggc cgcccggggg
    13201 gccgccagcc tcctcgacgt cagccgggtc gtcctcggcg gcgaggcact gcgcggcatc
    13261 gagccgatcc tgcgcgagga gatcgacgcc gccgtcaacc gcacctccgt cgcccgcgcc
    13321 atccgcgccg tcgccgtcga acagagcgtc atcggcgaca ccgtcggcgc cgtcggggcg
    13381 gcctcactgg tgctgcacgg caactacgcg ccggggtggc ggatgctgac cgacgtgtcc
    13441 gggtgacctc gcgggtgtca gccctcggcg ccgagcggcg gagccaccag ggcggccagt
    13501 tcgtccgggg tgcgagggcc cggcgcggtg gcgtccagca ggccctgctc gcgcagcagc
    13561 cgggcggccg cgacgcccca gggcagccgt agccccgcct gccggagcag gtcggtgcgg
    13621 gcgagcatcg tggcggccgg gccgatgtgc gcgccggacg gggtgagcag ggccgcgtcg
    13681 tcggcccagc gcagggcgag atcgacgtca tgggtggcca tcaccaccgt cgtgccggtg
    13741 ccgcacaggt cgtcgagggt gctcaacagc cgctcctgac catcgggatc cagcccggcg
    13801 gtcggctcgt ccaggatgag cacgcggggc cgcatcgcca ccgcaccggc gatcgcggtc
    13861 cgcttgcgct ggccgtagga gagcagatgc gtgggccggt cggccagcgc cgtgatgtcc
    13921 agggcggcga gcgcctcgcc gacccgggcc cgcacctcgg catcgggcag accgaggttg
    13981 agcgggccga acgacacgtc ctggccgacg gacgcggcga acaactggtc gtccggatcc
    14041 tgcacgacca gctggacggt ggtgcgcagc cgggtcaggc ccttgcggtc gtggcgcacg
    14101 ggccgcccct cgacggtcaa ctcgccgctg cgcggccgca gtccgccgct gagcagccgc
    14161 atcagcgtgg tcttgccact gccgttgcgt ccgagcaggg ccagcgcgcg cccttcgcgc
    14221 acctcgaagt cgagcccgct gagcacggcc gggccgtcct cgtaggcgaa ggaggcgccc
    14281 cgcagggcga ccagcacggg ctcgctcatc gcagcggcct ttccagtacg aaggtgaggg
    14341 cggccacggt cgccaggagc acgacggcag ccgccgtgaa gcgggccgag acgtgggcct
    14401 cggggaccag gacgcgcagg gtgccgtcgt agccgcgtcc ggccagcccg tcctggagcc
    14461 gcgccgcccg gtcgaaggcg cgcacgaacg cggtggcgcc gagcccggcc agggaccgcc
    14521 actccgcggc ccggttggtg tgcccgagcc gggcggcctg ggcctcgcgg atgcggcgca
    14581 tcgagtccag gagcagaaag ctcatgcggt acgtcaccag ggccacgtcc acgacgggcg
    14641 cgggcacgcc ggccttcacc agccggggca gcagatcgga catcggtgtg gtgaacgcga
    14701 acagcagcac gccgagggag gcggccgagg tgcgcagcag caactccccg gcccggaccg
    14761 gcccgtcggg cgccggggag acgaaaccgt cgggcccgcc gacctggacg agcagggtga
    14821 tcgcgccggt cgcgcagaac ccgagcggca cccggtaggc gcgccagagc cggcgggccg
    14881 gcacacccgc cgggcccagc agcacgacga gcgccgtcac cagcaccagg gccgcgcccg
    14941 gccacggcgg cagcgagatc gccagcaggg tgagtccgag cccgagcacg gccttgtcca
    15001 cgggatggcg gtggcgccag cggctgctgt gcgccgccgc gtcgatcggc agcacgggcc
    15061 tcaggtccgt tcggccgagg actcgtcgga ggccctctcc ggcgccgccg tgccctgggc
    15121 ctccagccgc gccagcgcgc gctgctcacc ctggcggcgt ccccggtgca gaccgaagta
    15181 gtaggtgagc acgcccgtgc ccagtgccgc ctggagggcg aacagcgccg actcgatctc
    15241 cccggacggc ggttcgtaca gcggcgagaa ccacggctcg tagtccggct cgatctccgt
    15301 gatggccgtc tccgcctcgg cgtcggcgcc cgtgaacggc tccttcttgt ggtcgccgag
    15361 cccgagggcc agcggcagca cggcgagcgc caccacgacc agcaccagca gagcgttgat
    15421 cttcgcgtta cggctcatcg ggccaccgcc tcggtcccgg cggcggaccg cccgcctgcc
    15481 gtgaggacgc ccagccggac cagttcgccc ttgctggact ggctcagcag gcgcatcacc
    15541 aacacggtga ggagcccctc gctcaccgcg agcgggatct gcgtgacggc gaagatggag
    15601 ccgaacttgc ccagcgcccc caggaacccg ctgctcgggt cggggaacgc gagtgccagc
    15661 tgcacgctgg tcacgcagta cgtggacagg tcggcggcga acgcgccgaa gaacaccgcg
    15721 accatcagcg gcacgtcgta ccgccggagc agccggtaga gggcgtatcc ggcccagggc
    15781 ccgacgatgg ccatcgagaa gacgttggcg ccgagcgtgg tcagcccgcc gtgggcgagc
    15841 agcagcgcct ggaagagcag ggtgatggtg cccagcacgg ccatgatcgg cggccggaaa
    15901 aggatcgcgc cgagccccgt gccggtggga tgcgagcaac tgcccgtcac cgagggcagc
    15961 ttcagcgcgg acaggacgaa cgtgaaggcc ccggaggcgc cgaggagcag ggtgctctcg
    16021 ggatgctcct tgacctcacg ggtgagggag cggactccgt ggacgacgaa cggcgcggac
    16081 gcgacactcc aggcgatcgc gtgcgccgga ggaaggaaac cctcggctat gtgcat
//
