LOCUS       reptomyces_RBGC_250012 16545 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_250012
VERSION     Streptomyces_RBGC_250012
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001280885.1
  ORGANISM  GCF_001280885.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1503
                     /protein_domains="PF02589"
                     /protein_domains="PF11870"
                     /protein_domains="PF13183"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197865"
                     /pseudo=False
                     /translation="MTGTFVGMPSFPAFPAFPEAAREAVGDGVLRANLRHATHTIRDKR
                     ARAVAELADWDRLRAAGKAVKDHTLRHLDRYLLQLEESVTAAGGTVHWAADADEANRIV
                     TGLVLATGHREVVKVKSMATQEIGLNEALEAAGIAAYETDLAELIVQLGHDRPSHILVP
                     AIHRNRAEIREIFAAEMGRWGRPAPDGLGDDPRELAEAARLHLREKFLRAKVAVSGANF
                     MVAETGTMVVFESEGNGRMCLTLPETLISVVGIEKVVPTFRDLEIFLQTLPRSSTAERM
                     NPYTTMWTGLGPSRGADGDGPSAFHLVLLDNGRTDTLADEVGRQALRCIRCSACLNVCP
                     VYERAGGHAYGSVYPGPIGAILSPQLRGTGSEIDASLPYASTLCGACYEVCPVAIDIPE
                     VLVHLRERVAQGGPVTREGVRVRIRPAHGHTAERAAMRAARLLLDRPAALRAGERLLAR
                     ARRLRPRRLPGPGRAWTDARDLPELPPEPFRDWWARERGGRA*"
     CDS             1501..2138
                     /protein_domains="PF02589"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197866"
                     /pseudo=False
                     /translation="MSSRDRILGRIRRAVADGAPDPAVPRDYFQVHGTRTPAQTADLLA
                     ANLAEYRAKVHRVDEDGLAPLLMRLLAARGAQTVLVPPALPPYWLSAADPTRIHDRAVS
                     TAGELDRVDSVVTGCALAIAETGTIVLDGGPEQGRRRITLVPDHHICVVRVPGQVVDSV
                     PQALRRLDPTRPLTWISGPSATSDIELDRVEGVHGPRTLEVVLLTGPAE*"
     CDS             2136..2533
                     /protein_domains="PF00903"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197867"
                     /pseudo=False
                     /translation="MSPMPAYIALTALVVHDYDEAIDFYTRALGFTLVEDTARPDGSRW
                     VVVRPNGATEAALLLARAKDEAQRSRVGDQTGGRVGFFLYTDDFARDHTRMTAEGVRFL
                     EEPRHETYGSVAVFEDLYGNRWDLLEPA*"
     CDS             complement(2589..3124)
                     /protein_domains="PF03745"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197868"
                     /pseudo=False
                     /translation="VDGRDRDGEGRARSARPRDGLGRPLPYGAQGVERQPEGVVRTPAE
                     TLAEAQRLLDGGMPFHAHEVFEDAWKSGPPAEAPLWRALAQLAVGLTHAARGNAVGGAR
                     LLRRGATALAGPDTGDGAGSSAGVGRAREPYGIDVPGLVRWARELAGRVEAGPAVDAAA
                     EAPRLAAPPDGPAPV*"
     CDS             complement(3627..4240)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197869"
                     /pseudo=False
                     /translation="MGLRQRLGRRRGGGGFAPQEITVKLTIPFVGEISGVWEPVDLERQ
                     AAWELYVELATRISVVELGEDEGLLREALSSLYTVFATTREILRRYGPAVAPRVAPGKV
                     TFGALAVNVLNLSIRPLLSKWHPLLTAHEAGRGSHVDPVAHERRWGRAAELRAEIESVR
                     KVLLSLAQALNEVAGAGDLITVRVPHQADSPAGTGTASGPS*"
     CDS             4325..4455
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197870"
                     /pseudo=False
                     /translation="LKRDAFVSHSHQADVPLAEALQKGLHGILKGLDITAPCSPHKE*"
     CDS             4461..7117
                     /protein_domains="PF13676"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197871"
                     /pseudo=False
                     /translation="MQRDAFISYSHKADVPLAASVHKGLHKIGRPWQSLRALNVFRDTD
                     SLGASTDLPGSILKELERSRYFIYIASPEAAASRWVREELVFWRDHPEAEARGRFLIAL
                     SDGEIHWDEAAGDFDWVRTTAIPAEVLRGVFRTEPLWVDLRRFRASEPAERALKPGEFR
                     GKVATLAAAVHGCTKDELESEDLRQQRRRNRTKNGALALLAALAVATTSAFFYATAKRE
                     EALARARTSASQALSARAVQIADIDPRKSAQYALYADQVKPTSESAQALARAVEANANA
                     ARHFQGGSGVAADFVGSGGSSSPTRVAVSRDGSTFAYCTGWDADAPKGEQQHIHLFDIR
                     SGKDLPVLQAKGLPLGGGVFELSADGGLLFMERSFNVIDVWDVRRGKLLREIVASKGED
                     LAGAFMHLKAFALSRDGSRMAAAFHEPNVDALRMAVWDTASGAELSRSDAGSDAVTLSF
                     DDAGKLHASPRAEPPTSGAALITAPTPDNRQILIGAENATVAIYDTQRRKQRTLGSFGF
                     QVQSLSASGDGMWVAAGSDDGAVSLFRGSAPTVRTLPNDDGLRPAELSDDGRVGFRKNA
                     QGGTDIWLLTDPNTGPIKAGSLLHGAEAFTASRDGRRVVFADSAGSLSVWDGPTSGSKE
                     RTLSAKGPYLYNGKGTHTIETVGDDQHVVGVWPQGVMVVDLRTMEVSQVLTDKKGIDRL
                     AVSKDARVLAATDVFGTATVWRWTADGKLRHVRETKVTGQRVDDVVVSDDGSKVAVVDS
                     DSRISVLDVSDGTVVTASVVARNAHTRAVFSPDSRLVMQASDTDTESRLNFWDAATGDT
                     LGSWPLGGPGFVRIFPVPDGGLLTLTADGSLTRRGIDITTWRRTLCALVPDELSGPEYE
                     RYLSDLEVSAPCRH*"
     CDS             7212..7411
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MSRLVGGGGIRPFPGWRVRGFGWVVVGADACADWGGGGCSGHVGL
                     VTGLRVSARSGRVNPPAASGS"
     CDS             7301..7437
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MRGLGWRGLLGARGLGDGAAGFGQIGEGQPACCVRIMTCCQEPCT
                     "
     CDS             7499..9171
                     /protein_domains="PF02518"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197872"
                     /pseudo=False
                     /translation="MVRVGSSPGSPGPTSPVAWALPALLTAAAAAIAVAQVSAPARTPV
                     AWIGAVAFVAVALSCGEAARRGKAVAALRLTVAAHEAALHRQQAETVRLAQELLPDVVE
                     RLRKGEFPEEVLASLEEPDIHGPGLTPEFRAAHHAVLRSVLDAVVAEEDLRDSAQRAFV
                     NIARRVQAIVHQQAQELREMEDRHGRSPEVFGDLLRLDHGTALIGRLADSIAVLGGARP
                     GRQWSKAVPLYSVLRGAMSRIIDYQRVELHSVSQVAVVGPAVEPLIHALAELLDNATRY
                     SPPQTKVHLTAVDVNSGIAVEIEDGGVSMSEEARKRAERMLRQAQQGIDLTDLGETPRL
                     GLAVVGRLSQAYDFQVSLRASAYGGVRAVLVIPQQLITTASAATGVAHGIGTASGPRAA
                     LPPTPAGAAVTGAAVADSGVPAARPVTGPRMPAAADEVPAVTERTPNGLPQRRRKTRAV
                     APEPIATGDRITAAAEAAADRAGYGYGAVPEPAPDPQPEVQPGMWLAAFQGGLSGDSQT
                     AASQTAASQTTASQTTASRGGAASQNTDASPASASKGEQP*"
     CDS             9169..9575
                     /protein_domains="PF03259"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197873"
                     /pseudo=False
                     /translation="MSQQQTNMDWMLKDLAESVPQTRHVVVLSADGLRMAQYGAETDTA
                     DRLAAACAGLQSLAGAVASELPGSSGRMRLVVIEMDGGFFYLMAAGAGAFLAVLADEGV
                     DAGLMGQRMRDLVARIGEHLSSPPRRDGQPA*"
     CDS             9573..9931
                     /protein_domains="PF05331"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197874"
                     /pseudo=False
                     /translation="VSNPGGDWEDGTPERLYVITGGRSGGLVPTHVDLVTLIIAKSGPR
                     PGMQPEHAAIMRLCQSPLSVAEISAYLGLPVSVVTVLLGDLLAAKHVLSRPPVAPAKLP
                     DLALIEAVIDGLRKL*"
     CDS             9913..10532
                     /protein_domains="PF03029"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197875"
                     /pseudo=False
                     /translation="MDFESSDRATAPRREDALPATAAAAVKVVIVGGFGVGKTTLVGSV
                     SEIRPLTTEETMTQAGVGVDDTAGVERKTSTTVAMDFGRISINEELVLYLFGTPGQERF
                     WFLWRGLFEGALGAVVLVDTRRLEVSFDVIGRLEERGVPFVVAVNSFPDAPEHPLEELR
                     AALDLPASVPLVFCDARRRDSSRDVLMTLMRYLHSLAATPEAL*"
     CDS             10530..11908
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197876"
                     /pseudo=False
                     /translation="VSTTPVPQPGAAAPPPGCPAHRLYGPEAEADPMGLYEKLRAEYGA
                     VAPVLVQGDLPAWLVLGHRENLDVARTPSRFARDPRHWRDQQEGNVPADHPLTPMTAWQ
                     PVCHFVDGVEHERLRGAITESLERFDRRGVRRYVKRFADQLIDAFVESGKGDLVAAFAE
                     PLPMLVMTQLVGAPESYGPRLVEAARDMIQGTETAVASFEYISVTLRELVARKREVPGR
                     DFTTWLLEHPTALGDEEIVEHLRLVLIAAFETTANLIANTLRVVLTDRRFRANLSGGHM
                     TLPDALEQVLWDEPPLMTVLGRWATGDTELAGTRIKAGDMLLLGLGAGNVDPEIRPDAT
                     EPVHGNRSHLAFSSGPHECPGQDIGRAIADTGIDTLLTRLPDLELAVPEDELQWKSSLM
                     SRHLVALPVRFTPRGSTVTGSTPVPRPAAQPPRTAPTAVPAAGERPAGRASWWARLRRR
                     R*"
     CDS             complement(11912..13029)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197877"
                     /pseudo=False
                     /translation="MAPAYGENTRPSRIGWQLPPFYWPFERGLIHPKAAELEERSIAWI
                     DAFGLYPDATERAWGLATRSSDLVSRILPYGDVETMLLFAQWSYWAFAADDWQDSDTGA
                     ARTAAVADHGARLIRTLEVPGSGLLAPGPHTAALDDLVARTRSILTSEQLHRLTEGLRD
                     WIFGAAAQTATDERGIMPSLNDFASTRISVGATRFLLTWCDVANGIHVPGDVLYSAPVQ
                     ALTDAAGFIVACDNDVFSYNKDDHHQPLEQNLLNVLARHHGCTPAEALPAAYALRDRSV
                     TLFVRLREQLARNADEQLARHLVSVEHWVSGDTEYHNRAPRYASPRNRNALPVEGASFD
                     ITWSDTPSDPSTEPLPIPALAWWWQQLDDSSR*"
     CDS             complement(13033..13943)
                     /protein_domains="PF13649"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197878"
                     /pseudo=False
                     /translation="MDRNLVIQTPAGGQEFDESQVPLYYSRKTVEILHKYGPGPRVHFH
                     MGLFAPGATPNTTVTQRVLKRRIVESQEAIVEHAARSWGAYTTPPGSVLDIGCGVGGGS
                     LYWAQEHGATVTGLTVAADHIPVIEDFARQAGVGDRVTPLLADVHAFTADRKYDAAYAN
                     ESSGYMDRERLFQVVARSLKPGGWFGIQEHFICRPEWTEFIDGYYKTRLGTLTEYLAAA
                     EAAGFELEQDEDVTDRVAEFWVQSMAWNTAELDRAEGCGTPSHWSCERLRESAITHGKL
                     FRIWRDHALETRLLLFRLGGGG*"
     CDS             complement(14124..14710)
                     /protein_domains="PF00857"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197879"
                     /pseudo=False
                     /translation="MTATADRTRPTLDDGTALVLIDLQQGILALPTTRPAAEILANGIT
                     LAEAFRARKLPVVLVRVAWSPDGGDLPTTDVDRPGPAAAPPAAFSEIPAELAALGDVVV
                     TKRHWGAFTGTELDLQLRRRGIHRIVLAGISTSVGVESTARTAWEHSYSLVFAEDATAD
                     TDPASHAHSFGKIFPRIGKVSTTAEIIAALNT*"
     CDS             14842..15398
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197880"
                     /pseudo=False
                     /translation="MRTNAGESRPSLTPALTGAELTRWYWTLAELSALAREMGLSAGGG
                     KVALTARLAAALDGLRPPEPVRVRRRSTGRQLTAPVDGDTVIPEGQRCSQVLREYFVRE
                     IGPGFHFDAFMRDYVARHAGHTLAEAVAHWHGTRARAAEPQEVAAQFEFNRFLRDWHAR
                     HPEGTRPQALAAWQAHRALPKG*"
     CDS             complement(15440..16545)
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4197881"
                     /pseudo=False
                     /translation="VDVYQGAVAALVPFLVSERAYGYAAASGVVLAASLLSSVVQPLFG
                     ALTDRRPMPWLIPLSTAAAGLGIALVGADAGYPATVAAVALSGLGVAAYHPAAARLVRT
                     SAGGPGHAAMSWFALGGNIGFACAPLLVVGALSVPGPAGWWLLAVPAALGVVLNLPRPA
                     PDRTAGPEASQAAGGAHASAGPEDRRAFLRLSLVVVVRSVAFIGLSTFIALYVRERGGG
                     ETAGAVALFALFAGSAGGTLLGGRLASRWGRVTTVRRAYAAAAPAVAGVLFLPLPLVYV
                     CAALAAAALYVPFSLQVTLGQDYLPARMGTASGVTLGLTVSVGGVASPFIGALADATSV
                     RTALLPLAVLPLLAWALARRLPEPAPGA*"
ORIGIN
        1 atgacgggca ccttcgtggg gatgccatcg ttccccgcct tccccgcctt cccggaggcg
       61 gcgcgggagg ccgtcgggga cggggtgctg cgcgccaacc tccggcacgc cacccacacc
      121 atccgcgaca aacgggcccg ggcggtcgcc gagctggccg actgggaccg gctgcgcgcg
      181 gcgggcaagg ccgtcaagga ccacaccctg cgccatctcg accgctacct gctccagctg
      241 gaggagtccg tgacggccgc cggcggcacc gtccactggg cggccgacgc ggacgaggcc
      301 aaccggatcg tgaccgggct ggtgctggcc accggccacc gggaggtggt caaggtcaag
      361 tccatggcca cccaggagat cggcctcaac gaggccctcg aggcggcggg gatcgccgcg
      421 tacgagaccg acctggccga gctcatcgtc cagctcggcc acgaccgccc ctcgcacatc
      481 ctcgtcccgg ccatccaccg caaccgggcc gagatccggg agatcttcgc ggcggagatg
      541 ggccgctggg gccgccccgc gcccgatggc ctcggcgacg acccgcgcga gctcgccgag
      601 gccgcccgcc tccacctgcg cgagaagttc ctgcgcgcga aggtcgcggt ctccggcgcc
      661 aacttcatgg tcgccgagac gggcaccatg gtcgtcttcg aatccgaggg caacggccgg
      721 atgtgcctca cgctgcccga gaccctcatc tcggtggtcg gcatcgagaa ggtggtgccg
      781 accttccggg acctggagat cttcctccag acgctgccgc gctcgtccac ggccgagcgg
      841 atgaacccgt acacgacgat gtggacgggg ctgggccctt cgagaggggc ggacggcgac
      901 ggcccctccg ccttccacct cgtcctcctc gacaacggcc gcaccgacac cctcgccgac
      961 gaggtgggcc gccaggcgct gcgctgcatc cgctgctccg cgtgcctgaa cgtctgcccg
     1021 gtgtacgagc gcgccggcgg ccatgcgtac ggctcggtct accccgggcc gatcggcgcc
     1081 atcctcagcc cccaactgcg gggtacgggc agtgagatcg acgcctcgct gccgtacgcg
     1141 tccaccctgt gcggggcctg ctacgaggtc tgcccggtcg ccatcgacat ccccgaggta
     1201 ctcgtccacc tgcgcgaacg ggtggcccag ggcggcccgg tgacccgcga gggcgtccgc
     1261 gtgcggatcc gccccgcgca cggccacacc gccgaacggg ccgcgatgcg ggccgcccgc
     1321 ctgctcctgg accgcccggc cgcgctgcgc gcgggggagc gcctcctggc ccgggcccgg
     1381 cggctgcggc cgcgccggct gccgggcccc ggacgtgcat ggacggacgc ccgggacctc
     1441 cccgagctcc cgccggagcc gttccgcgac tggtgggcgc gggagcgggg agggcgggca
     1501 tgagcagcag ggaccgcatc ctgggccgga tccgccgggc cgtggcggac ggcgccccgg
     1561 accccgccgt cccccgggac tacttccagg tccacggcac ccgtacgccg gcgcagacgg
     1621 cggacctcct cgccgcgaac ctcgccgagt accgcgcgaa ggtccaccgg gtggacgagg
     1681 acggcctcgc gccgctcctg atgcggctgc tggccgcgcg gggcgcacag accgtgctcg
     1741 tgccgccggc cctgcccccg tactggctct cggcagccga tccgacccgc atccacgacc
     1801 gggccgtgtc cacggcgggc gaactggaca gggtggacag tgtggtgacc ggctgcgcgc
     1861 tggcgatcgc cgagaccggc acgatcgtcc tcgacggcgg ccccgagcag ggccgtcgcc
     1921 gcatcaccct cgtccccgac catcacatct gcgtggtccg ggtgcccggc caggtggtcg
     1981 actcggtccc gcaggccctg cgccgcctcg acccgacgcg gccgctgacc tggatctccg
     2041 gaccctccgc caccagcgac atcgagctcg accgggtgga aggtgtgcac ggcccgcgca
     2101 ccctggaggt ggtcctgctg accggaccag cagaatgagt cccatgcccg cttacatcgc
     2161 cctcaccgcg ctcgtcgtcc acgactacga cgaggccatc gacttctaca cccgcgccct
     2221 cggcttcacc ctcgtcgagg acaccgcccg cccggacggc tcccgctggg tcgtggtccg
     2281 cccgaacggt gccaccgagg cggcactgct gctggcccgc gccaaggacg aggcccagcg
     2341 ctcccgggtc ggggaccaga cgggcggccg ggtcggcttc ttcctgtaca cggacgactt
     2401 cgcccgggac cacacccgga tgacggcgga gggcgtccgc ttcctggagg agccgcgcca
     2461 cgagacgtac ggctcggtgg ccgtcttcga ggacctctac ggcaaccgct gggacctcct
     2521 cgagccggcg tagccgtcgc ccggccccgg ccgtccgcag cggcaccacc ggcgtgcccg
     2581 gccggggtca gacaggggcc gggccgtccg gcggcgcggc gagccgcggg gcctcggccg
     2641 ccgcatcgac ggccggcccg gcctccaccc gcccggccaa ctcccgggcc cagcggacca
     2701 gccccggcac gtcgatcccg tagggctccc gcgcccggcc gactccggcg ctcgaccccg
     2761 ccccgtcccc cgtgtcgggc ccggccaggg cagtggcccc gcggcgcaac aggcgggcgc
     2821 cgccgacggc gtttccgcgt gcggcgtgcg tgaggccgac cgccagctgc gccagagccc
     2881 gccacagcgg cgcctcggcc ggcgggccgg acttccaggc gtcctcgaac acctcgtgcg
     2941 catggaacgg catcccgccg tccagcagcc gctgcgcctc ggccagcgtc tcggcgggcg
     3001 tccgcacgac cccctcgggc tgccgctcca ccccctgcgc cccgtagggc agcggccgcc
     3061 ccagcccgtc ccggggccgc gcgctccgcg cccgcccctc accgtcccga tcccgtccgt
     3121 ccaccgggcc atcctccctc ccgccggaaa ccggtgcatg cgcacccctc cacgtggggt
     3181 aatgttctgc atgtgccgca gggacggggg aaaccccaga tcaacagcac aacgggacgt
     3241 ggcgcagctt ggtagcgcac ttgactgggg gtcaaggggt cgcaggttca aatcctgtcg
     3301 tcccgaccag aggttcgcct cgtggtcgca tttcggagcc ctgtctcact tcggtgaggc
     3361 agggctcttg cgcgttctct gcggctgtcg tatcaccttt cgtcacagac cgggaagcgg
     3421 tcagccaggt tgacggggac ggccttgggc gggcttgggc gctcggcccg cagcgccgac
     3481 cgtctccacg tgcggaggaa ctccccggcc gaccggggtg gcttaggggg tgtcgtcaaa
     3541 gtcccgtctg gccggcgggg tctggcacgc gcgctcgcgg cgttgtcgtc ggtcgacgac
     3601 gcgagcgtcg cctccctcct cccccctagg acggtcccga cgcggtcccg gtacccgccg
     3661 gggaatcggc ctggtgcggc acccgcacgg tgatcaggtc gcctgccccc gccacctcgt
     3721 tcaacgcctg ggccagcgac agcagcacct tgcgtacgga ctcgatctcc gcccgcagtt
     3781 cggccgcccg cccccaccgg cgctcgtgcg cgaccggatc gacatggctg ccacgccccg
     3841 cctcgtgcgc ggtgagcagc gggtgccact tgctgagtaa tggcctgatg gacaagttca
     3901 ggacattcac cgccagcgcc ccgaaggtca ccttgccggg tgccacgcgg ggtgccaccg
     3961 ccggcccgta ccggcgcagg atctctcgtg tcgtcgcgaa gaccgtgtac agcgacgaca
     4021 gcgcctcccg cagcagccct tcgtcttcgc cgagctcaac gacggagata cgggtggcca
     4081 gttcgacgta cagctcccag gcggcctgcc gttcgaggtc cacgggttcc cacacgccgc
     4141 tgatctcgcc gacgaacggg atggtgagct tgaccgtgat ctcctgcggc gcgaacccgc
     4201 caccaccgcg ccgccgcccc aacctctgtc gcaaacccat ccccgcaacc ttcccgtggc
     4261 aagaactccg catgccactc tacgagttgc gaggtcgagt gcggggcgtc aggggggacg
     4321 atcttgaagc gcgatgcctt cgtctcccac agccatcagg cggacgttcc gctggcggag
     4381 gcactccaga agggactgca cggcatcctc aagggcctgg acatcaccgc gccctgcagc
     4441 ccccacaagg aatgagtaca tgcaacgcga cgccttcatc tcgtacagcc acaaggccga
     4501 cgtccccctg gccgcttccg tccacaaggg actgcacaag atcggccgtc cctggcagag
     4561 cctgcgcgcg ctcaacgtct tccgggacac cgacagcctg ggcgcgagca ccgatctccc
     4621 gggttccatc ctgaaagagc tggagcggtc ccggtacttc atctacatcg cctctcccga
     4681 ggcggcggcg tcgcgctggg tccgcgagga gctcgtcttc tggcgtgacc accccgaggc
     4741 cgaagcccgt ggccggttcc tgatcgcgct cagtgacggc gagatccatt gggacgaggc
     4801 agccggcgac ttcgactggg ttcgcacgac cgccattccc gccgaggtat tgcgtggcgt
     4861 gtttcgcacc gagccgctgt gggtggacct acggaggttt cgcgcgagcg agccggccga
     4921 acgtgccttg aagccgggtg agttccgcgg caaggtggcc accctcgcgg ccgcggtcca
     4981 tggctgcacc aaggacgagc tggaaagcga ggacctgcgc cagcagcgca ggaggaaccg
     5041 caccaagaac ggggcgctgg ccctgctggc ggccctcgcc gtagccacca cgagcgcctt
     5101 cttctacgca actgcgaaac gcgaagaggc cctcgcccgc gcccgtacct ccgcctccca
     5161 ggccctctcg gcccgtgcgg tgcagatcgc tgacatcgac ccgcgcaagt ccgcccagta
     5221 cgccctctac gccgaccagg tcaagccgac cagcgagtcc gcccaggccc tggcccgggc
     5281 ggtggaggcc aacgccaacg cggcccggca cttccaaggc ggctcgggcg ttgccgccga
     5341 cttcgtcggc tccggcggca gcagcagccc gacgcgggtg gcggtgagcc gcgacggcag
     5401 cacgttcgcc tactgcacag gatgggacgc cgacgccccg aagggtgagc agcagcacat
     5461 ccacctcttc gacattcgct ccggcaagga cctgccggtg ctgcaggcga agggcttacc
     5521 actcggtggc ggtgtcttcg aactcagcgc cgacggcggg ctgctcttca tggagcgctc
     5581 gttcaacgtg atcgacgtgt gggacgtacg acgggggaag ctgctccgcg agatcgtcgc
     5641 gagcaagggc gaggacctcg caggcgcctt catgcacctc aaggccttcg cgctgtcccg
     5701 tgacgggagc cggatggccg cggccttcca cgagccgaac gtcgacgctc tgcgcatggc
     5761 ggtctgggac acggcatccg gcgccgagct cagccgttcc gacgccggct cggatgccgt
     5821 cacgctctcc ttcgacgacg ccggcaagct gcacgcctcc cccagggccg agcccccgac
     5881 gtccggtgca gccctgatca ccgccccgac gcccgacaac cgccagatcc tgatcggcgc
     5941 cgagaacgcg accgtcgcca tctacgacac ccagcgccgc aagcagcgca ccctcggttc
     6001 gttcggcttc caggtgcaga gcctctccgc ttccggagac ggcatgtggg ttgccgccgg
     6061 atccgacgac ggcgcggtgt ccctcttccg cgggagcgcc ccgaccgtcc gaacgctccc
     6121 caatgacgac ggactcaggc ccgccgagct gtccgatgac ggccgggtcg gcttccgcaa
     6181 gaacgcacag ggcggtactg atatttggct gctcaccgat ccgaataccg gcccgatcaa
     6241 ggcaggcagc ctcctccacg gggccgaggc cttcacggcc tctcgtgacg gccgccgcgt
     6301 cgtgttcgcg gacagcgcgg gcagcctctc cgtctgggac ggccccacca gcgggagcaa
     6361 ggagcgcacg ctcagcgcca agggccccta cctctacaac ggcaagggaa cgcacaccat
     6421 cgagacggtg ggcgacgacc agcatgtcgt gggcgtctgg ccacagggcg tcatggtggt
     6481 cgacctgcgc accatggagg tcagccaggt gctgacggac aagaagggca tcgaccggct
     6541 cgcggtcagc aaggacgcca gggtgctggc agccaccgac gtcttcggca cggccaccgt
     6601 gtggcgctgg accgcagacg gcaagctgcg gcacgtccgc gagacgaagg tcaccggcca
     6661 gagggtcgac gatgtcgtgg tgagcgacga cgggtcgaag gtggcggtgg tcgacagcga
     6721 ctcccgcatc tccgtcctcg acgtgtccga cggcactgtt gtcaccgctt ccgtcgtggc
     6781 ccgaaacgcc cacactcgcg ccgtgttcag cccggactcc cggctcgtca tgcaggcctc
     6841 cgacaccgac acggagagcc gcctgaactt ctgggacgcg gcgaccggcg acacgctcgg
     6901 ctcctggccg ctgggcggac ccggtttcgt gcggatcttc cccgtccccg acggcggcct
     6961 gctcaccctc accgccgacg gctccctcac ccggcgcggc atcgacatca ccacctggcg
     7021 ccgcaccctg tgcgccctgg tcccggacga gctctccggg cccgagtacg agcgctacct
     7081 gagcgacctg gaggtcagtg ccccctgccg ccactaggcg cgatgccctg cgatgccact
     7141 tacgtgaggg aggagttcgc gggagaccgt cgtcgcccgg gtcgagtcct ggccgcatga
     7201 cgagcgggcg atgagccgct tggtcggcgg tggtgggatt cggccgttcc ctgggtggcg
     7261 ggtcaggggc ttcgggtggg tggtggtggg ggcggacgcg tgcgcggact ggggtggcgg
     7321 gggctgctcg gggcacgtgg gcttggtgac ggggctgcgg gtttcggcca gatcggggag
     7381 ggtcaacccg cctgctgcgt ccggatcatg acctgctgtc aagagccgtg cacatagacg
     7441 ctaagattcc gggccgttgt catatgatca ttcgctttcg atcgtttgag ggttctgatg
     7501 gttcgcgtgg gatcgtcgcc cggaagtcca gggcccacct cacccgtcgc atgggcgctg
     7561 cccgccctgc tgaccgccgc tgctgcggcg atcgccgtgg cgcaggtgtc cgcacctgcc
     7621 cgcacccccg tcgcctggat cggcgccgtg gccttcgtgg ccgttgccct gtcctgcggt
     7681 gaggccgccc ggcgcggcaa ggcggtggcc gcgctgcggc tgacggtcgc cgcgcacgag
     7741 gcggccctgc accggcagca ggccgagacc gtgcggctgg cgcaggagct gctgcccgat
     7801 gtcgtggagc ggctgcgcaa gggggagttc cccgaggagg tgctcgcctc cctggaggag
     7861 cccgacatcc acgggcccgg cctgacaccg gagttcaggg cggcgcacca cgccgtgctg
     7921 cgctcggtgc tcgacgccgt cgtcgccgag gaggacctgc gcgactccgc gcagcgggcc
     7981 ttcgtcaaca tcgcccgccg cgtccaggcc atcgtgcacc aacaggccca ggaactgcgg
     8041 gagatggagg accggcacgg ccgcagcccg gaggtgttcg gcgacctgct gcggctcgac
     8101 cacggcacgg ccctcatcgg ccgtctcgcc gactccatcg ccgtactcgg cggtgcgcgg
     8161 cccggccgcc agtggagcaa ggccgtcccg ctgtacagcg tgctgcgcgg tgccatgtcg
     8221 cggatcatcg actaccagcg cgtcgagctc cactcggtct cgcaggtcgc cgtcgtcgga
     8281 ccggccgtcg agccgctcat ccacgcgctc gccgagcttc tggacaacgc cacccgctac
     8341 tcgccgccgc agaccaaggt ccatctgacc gccgtggacg tgaactcggg catcgccgtc
     8401 gagatcgagg acggcggcgt gagcatgagc gaggaggccc gcaagcgggc cgagcgcatg
     8461 ctccgccagg cgcagcaggg catcgacctc accgacctcg gggagacccc gcgcctgggc
     8521 ctcgccgtgg tcggccggct ctcgcaggcg tacgacttcc aggtctcgct gcgcgcgtcg
     8581 gcgtacggcg gcgtacgggc cgtgctcgtc atcccgcaac agctgatcac caccgcgtcc
     8641 gccgcgaccg gcgtcgccca cggcatcggc accgcctcgg gcccccgggc cgccctcccg
     8701 ccgacgccgg ccggcgcagc cgtgaccggg gcagcggtcg cagactccgg agtaccggcc
     8761 gcccgcccgg tcaccggccc ccggatgccg gcagccgccg acgaggtgcc cgccgtgacc
     8821 gagcggaccc cgaacggcct gccgcagcgc cgccgcaaga cccgcgccgt ggcgccggag
     8881 ccgatcgcca ccggggaccg gatcacggca gcggccgagg cggccgcgga ccgcgccgga
     8941 tacgggtacg gagccgtgcc cgagcccgcg cccgaccccc agcccgaggt acagcccggg
     9001 atgtggctcg ccgccttcca gggcggcctg tcgggggaca gccagaccgc cgcgagccag
     9061 accgccgcga gccagaccac cgcgagccag accaccgcga gccggggcgg cgcagcaagc
     9121 cagaacacag acgcctcgcc ggcctcggcg agcaaggggg aacagccatg agtcagcagc
     9181 agaccaatat ggactggatg ctcaaggacc tggccgagag cgttccgcag acccgccacg
     9241 tcgtcgtcct ctccgccgac ggcctgcgca tggcgcagta cggcgcggag accgacaccg
     9301 ccgaccggct cgccgcagcc tgcgccggac tgcagagcct cgccggagcc gtcgcctccg
     9361 aactcccggg cagcagcggg cggatgcggc tcgtcgtcat cgagatggac ggcggcttct
     9421 tctacctgat ggcggccggt gccggcgcct tcctcgccgt gctggccgac gaaggcgtcg
     9481 acgcgggcct gatgggccag cgcatgcgcg acctcgtcgc ccggatcgga gaacacctga
     9541 gcagcccgcc gcgccgcgac gggcagccgg cgtgagcaac cccggcgggg actgggagga
     9601 cggcactccc gagcggctct acgtgatcac cggcggccgc agtggggggt tagtccccac
     9661 ccacgtcgac ctcgtcacgc tgatcatcgc caagtcgggt cccaggcccg ggatgcagcc
     9721 ggagcacgcg gcgatcatgc ggctgtgcca gtcgccgctc tcggtggccg agatctccgc
     9781 gtatctcggc ctgccggtga gcgtggtcac cgtactcctc ggtgacctgc tcgccgccaa
     9841 gcacgtgctc tcccgcccac ccgtcgcacc cgccaaactc ccggacctgg cactgattga
     9901 ggcagtcatc gatggacttc gaaagctctg accgggccac cgcgccccgg cgcgaggacg
     9961 cgctgccggc cacggccgcc gccgcagtca aggtggtgat cgtgggcggc ttcggggtcg
    10021 gcaagacgac cctcgtcggc tcggtcagcg agatccggcc gctcaccacc gaggagacga
    10081 tgacccaggc cggggtcggc gtcgacgaca cggcgggggt ggaacgcaag acctccacca
    10141 ccgtggccat ggacttcggc cgcatcagca tcaacgagga gctggtgctc tacctcttcg
    10201 gcacgccggg ccaggagcgc ttctggttcc tgtggcgcgg cctgttcgag ggcgcgctcg
    10261 gcgcggtggt cctggtcgac acccgcaggc tggaggtcag cttcgacgtg atcggccggc
    10321 tggaagagcg cggagtaccg ttcgtggtcg ccgtcaactc cttccccgac gcgcccgagc
    10381 accccctgga ggagctgcgc gccgccctcg acctgcccgc gtccgtaccg ctcgtcttct
    10441 gtgacgcccg gcggcgcgac tccagccgcg acgtcctgat gacgctgatg cgctacctgc
    10501 actccctcgc cgcgaccccg gaggcactgt gagcaccacc cccgtccccc agccgggtgc
    10561 ggccgccccg ccgcccggct gcccggccca ccggctctac gggcccgagg ccgaggccga
    10621 ccccatgggc ctgtacgaga agctgcgcgc cgagtacggc gcggtggcgc ccgtcctcgt
    10681 ccagggcgac ctcccggcct ggctggtgct gggccaccgc gagaacctgg acgtggcgcg
    10741 caccccgtcc cggttcgccc gcgacccgcg ccactggcgg gaccagcagg agggaaacgt
    10801 tccggccgac caccccctga cgccgatgac cgcatggcag cccgtgtgtc acttcgtcga
    10861 cggcgtcgag cacgagcggc tgcgcggagc gatcaccgag tccctggagc gcttcgaccg
    10921 ccgcggtgtc cgccggtacg tgaagcgctt cgccgaccag ctgatcgacg ccttcgtcga
    10981 gtccgggaag ggtgacctgg tcgccgcctt cgccgagccg ttgccgatgc tggtgatgac
    11041 ccagctcgtc ggggcgccgg agtcctacgg cccgcgtctc gtcgaggcgg cccgcgacat
    11101 gatccagggc accgagacgg ccgtcgcgag cttcgagtac atctcggtca ccctccggga
    11161 actcgtggca cgcaagcggg aggtgcccgg ccgggacttc accacctggt tgctggagca
    11221 ccccacggcg ctcggcgacg aggagatcgt ggagcacctg cggctggtgc tgatcgcggc
    11281 cttcgagacg accgccaacc tgatcgcgaa caccctgcgc gtggtgctca cggaccgccg
    11341 cttccgcgcg aacctctccg gcgggcacat gacgctcccg gacgcgctgg agcaggtcct
    11401 gtgggacgag cctccgctca tgacggtcct cggacgctgg gccaccggtg acacggagct
    11461 ggccggaacc cggatcaagg ccggggacat gctgctgctc ggcctggggg cgggcaacgt
    11521 cgaccccgag atccggcccg acgcgaccga gcccgttcac ggcaaccgct cccacctggc
    11581 cttcagcagc ggcccgcacg agtgtcccgg gcaggacatc ggccgggcca tcgcggacac
    11641 cggcatcgac accctgctga cccggctgcc tgacctggag ctggccgtcc ccgaggacga
    11701 gctccagtgg aagtcctcgc tcatgtcccg ccacctggtg gcgctccccg tacggttcac
    11761 cccgcgcggc agcaccgtca ccgggtccac gccggtaccc cggccggccg cccagccgcc
    11821 ccggacggcg ccgacggccg tccccgccgc gggggagcgg ccggcgggcc gggcctcctg
    11881 gtgggcgcgc ctgcgccgcc gccgctgact tcagcgcgac gagtcgtcga gctgctgcca
    11941 ccaccaggcg agagccggga tcggcagcgg ctcggtgctc gggtcgctgg gcgtgtcgct
    12001 ccaggtgatg tcgaacgagg ccccctcgac gggaagcgcg ttgcggttgc gcggactggc
    12061 gtagcgtggc gcccggttgt ggtattcggt gtcccccgac acccagtgct ccacggagac
    12121 gaggtggcgc gcgagctgct cgtcggcgtt gcgcgccagc tgctcgcgca gtcggacgaa
    12181 cagcgtcacg gaccggtccc gtagcgcata cgcggcgggc agcgcctcgg cgggcgtaca
    12241 gccgtggtgc cgggccagta cgttgagcag gttctgctcc agcggctggt ggtggtcgtc
    12301 cttgttgtac gagaacacgt cgttgtcgca ggcgacgatg aacccggcgg cgtcggtcag
    12361 agcctggacg ggcgcggagt acagcacgtc acccggtacg tggatcccgt tcgccacatc
    12421 gcaccaggtc agcaggaacc gggtcgcgcc gaccgatatg cgtgtcgatg cgaagtcgtt
    12481 gaggctcggc ataatgcctc gctcatcggt cgccgtctgc gcggcggcgc cgaagatcca
    12541 gtcccgcagg ccctcggtga ggcggtggag ctgctccgag gtgagtatcg accgggtgcg
    12601 tgcgaccagg tcgtccagtg cggccgtgtg cggtcccggt gcaaggaggc cggagccggg
    12661 cacctcgagc gtacggatca gccgggcccc gtggtcggcg acggccgccg tacgagcggc
    12721 accggtgtcc gagtcctgcc agtcgtcggc ggcgaaggcc cagtagctcc actgggcgaa
    12781 gagcagcatc gtctccacgt cgccgtaggg gaggatccgg ctgacgaggt cggagctgcg
    12841 cgtggccagt ccccaggcgc gctcggtggc gtccgggtag aggccgaaag cgtcgatcca
    12901 ggcgatggag cgctcttcga gctcggccgc cttggggtgg atcaggcccc tctcgaacgg
    12961 ccagtagaac ggcggcagct gccagccgat gcgggagggg cgggtgttct cgccgtacgc
    13021 gggtgccatc gtcagccgcc cccgccgaga cggaacagca ggagccgggt ctccagcgcg
    13081 tggtcgcgcc agatgcggaa cagcttgccg tgcgtgatgg cggactcccg gagccgctcg
    13141 cacgaccagt gggacggggt gccgcagcct tccgcacggt ccagttcggc ggtgttccag
    13201 gccatggact ggacccagaa ctcggcgacg cggtcggtga cgtcctcgtc ctgctccagt
    13261 tcaaaaccgg ccgcctcggc ggcggccagg tactcggtga gggtgccgag gcgcgtcttg
    13321 tagtagccgt cgatgaactc ggtccactcg ggccggcaga tgaagtgctc ctggatgccg
    13381 aaccagccgc cgggcttcag cgaccgggcc acgacctgga agagccgctc gcggtccatg
    13441 tagccggagc tctcgttggc gtacgcggcg tcgtacttcc ggtcggcggt gaacgcgtgc
    13501 acgtcggcca ggaggggggt gacgcggtct cccacgcccg cctggcgggc gaagtcctcg
    13561 atcacgggta tgtgatcggc cgcgacggtg agcccggtga ccgtcgcacc gtgctcctgg
    13621 gcccagtaga gcgacccgcc gccgactccg cagccgatgt cgaggacgct gccggggggt
    13681 gtggtgtacg ccccccagct gcgggcggcg tgctcgacga tggcctcctg ggactccacg
    13741 atgcggcgct tgagcacgcg ttgggtgacc gtggtgttcg gcgtcgcccc gggggcgaag
    13801 aggcccatgt ggaaatggac ccttggtccg gggccgtact tgtggaggat ttccacggtc
    13861 ttgcggctgt agtagagcgg aacttggctc tcgtcgaact cctggccacc agcgggggtc
    13921 tggatgacaa ggttgcggtc catcggttct ccggtcatgc ggtcgcgtgg gggtgtcaat
    13981 cggccgcccc actctgccca taagcgatcg ataaaagtcc tcgttcactt gggtgatgag
    14041 cataaccaca gctgaaacgg caccaattca ggccatttga tgtcacgtca gatcatggcc
    14101 acgcgtgaat ggccggatat cgtcaggtgt tcagcgcggc gatgatctcc gcggtcgtgc
    14161 tgaccttgcc gatgcgcggg aagatcttgc cgaacgaatg ggcgtgggac gcggggtccg
    14221 tgtcggccgt ggcgtcctcg gcgaagacca gggaatagct gtgctcccag gccgtgcgcg
    14281 cggtggactc gacgccgacg ctggtggaga tgccggccag gacgatccgg tggatgccgc
    14341 ggcggcgcag ctggaggtcg agctcggtcc cggtgaaggc gccccagtgg cgcttggtca
    14401 cgacgacgtc gccgagggcg gcgagctcgg ccgggatctc cgagaaggcg gcgggcggcg
    14461 cggcggccgg gcccgggcgg tcgacgtcgg tggtgggcag gtcgccgccg tcgggcgacc
    14521 aggcgaccct gaccagcacc accgggagct tccgggcgcg gaacgcttcg gcgagcgtga
    14581 tgccgttcgc gaggatctcg gcggcgggcc tggtggtggg cagcgccagg atgccttgct
    14641 ggaggtcgat caggaccagg gcggtgccgt cgtcgagggt cgggcgggtg cggtcggctg
    14701 tggcggtcat gggatctcct cgggtggatc cgggcgtcac gggtcaggcc catgaaaccc
    14761 gggtcgcacc ttcccggccg cctggtccgt gccgaccggc gtggcggcgg ccgggcggtc
    14821 cccgccccta aaatgggaac atgcgtacga atgccgggga gtcccggccc tccctgaccc
    14881 cggcgctgac cggggcggag ctgacgcgct ggtactggac gctggccgaa ctgtccgcgc
    14941 tcgcgcgaga gatgggcctt tccgccgggg gcggaaaggt cgcgctgacg gcccggctgg
    15001 ccgctgcgct cgacgggctc cggccgccgg aaccggtccg ggtccggcgc cgcagcacag
    15061 ggcggcagct cacggccccc gtcgacgggg acaccgtgat cccggagggc cagcggtgca
    15121 gccaggtgct ccgggagtac ttcgtcaggg agatcgggcc cggattccat ttcgacgcct
    15181 tcatgcggga ctacgtcgcc cggcacgcgg gacacaccct cgccgaggcc gtcgcccact
    15241 ggcacggcac ccgcgcccgg gcggccgaac cccaggaggt cgccgcccag ttcgagttca
    15301 accgcttcct gcgcgactgg cacgcccgcc acccggaggg cacccggccg caggccctgg
    15361 ccgcctggca ggcccaccgc gccctcccga agggctgacc ccgggcggcc gggccgccct
    15421 tcaggggccg gccgcccttc aggcgcccgg cgcgggttcc ggcagccgcc gggccagggc
    15481 ccaggccagc agcgggagaa cggcgagggg gagcagggcc gtccgtacgg aggtggcgtc
    15541 cgcgagggcg ccgatgaagg ggctcgccac gccgcccacg ctgaccgtca ggccgagggt
    15601 gaccccgctc gccgtgccca tgcgggccgg caggtagtcc tggcccagtg tgacctggag
    15661 cgagaacggc acgtacaggg cggcggccgc cagtgccgcg cagacgtaca ccaggggcag
    15721 cggcaggaag agcacgcccg cgacggcggg ggcggccgcc gcgtacgccc ggcggacggt
    15781 ggtgacccgc ccccagcggg aggccagccg gccgccgagc agggtgccgc ccgcgctgcc
    15841 ggcgaagagg gcgaacaggg ccaccgcccc cgcggtttca ccgccgccgc gctcgcgtac
    15901 gtacaaggcg atgaacgtgc tcagcccgat gaacgcgacg gaccggacga ccaccacgag
    15961 ggagagccgc aggaaggccc ggcggtcctc gggcccggcc gacgcgtgcg cgcctcccgc
    16021 cgcctgcgat gcctccggtc cggccgtacg gtccggcgcc ggccggggga ggttcagtac
    16081 gactccgagc gccgcgggga cggccagcag ccaccagccc gccgggccgg gcaccgacag
    16141 ggcccccacg acgagcagcg gcgcacacgc gaagccgatg ttgccgccga gcgcgaacca
    16201 gctcatcgcc gcgtgcccgg ggccgcccgc gctcgtgcgg accagccggg cggccgccgg
    16261 gtggtacgcg gccacaccca gcccggacag ggcgaccgcg gcgacggtgg ccggatagcc
    16321 ggcgtccgcg ccgaccaggg cgatgcccag cccggcggcg gcggtgctca gcgggatcag
    16381 ccacggcatc gggcggcggt cggtcagcgc cccgaacagc ggctggacca cggaggacag
    16441 cagcgaggcg gccagcacga cgccggaggc ggcggcgtag ccgtacgcgc gctccgagac
    16501 caggaagggg accagggccg cgacggcgcc ctggtagacg tccac
//
