LOCUS       reptomyces_RBGC_266349 17062 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_266349
VERSION     Streptomyces_RBGC_266349
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001279455.1
  ORGANISM  GCF_001279455.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..1272)
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210115"
                     /pseudo=False
                     /translation="MSDVVSGPLSHRPVGGSRAHGKNRAASFGLDASVLVALLAASSAP
                     TPLYPLYQDQWGLSALAVTVVFSAYSLALLSALLTTGGLSDRLGRRPVLAGALGAQAVA
                     MVLLASADGAGSLTAARLLQGVATGAATSAAGAALLDLESPRHPGRSALTNTIAPVAGM
                     AAGVLVSTLLVRFAPAPTVTVYALMAALFAAQAIAVTFTTETVARRAGALRSLRPRLGV
                     PPAVRRTLLTTGTAIVAIWALGGFYSSLGPALVRLVAPNAPQAALGMVFFTLSAAAALT
                     MWVLRRADPLTTAIGGCLCVLPAAVLTLSGLHGVGLPSVHGGAALAGVAFGAVSQGVLR
                     MLLASLDERYRAATLAAYYVLSYLSMSLPAVAAGAATQHYGLRTTSHAYAAVAALLAAA
                     ALTALAVSRTRTRPRSSPRNRPLR*"
     CDS             1404..1612
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210116"
                     /pseudo=False
                     /translation="MSSAGLTPPEAARWAARAGLPLPDDRHCVVAATADHIHSVVGVLR
                     ELNFGDTPPAGAFRAEQEKHDAAV*"
     CDS             1600..2990
                     /protein_domains="PF01425"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210117"
                     /pseudo=False
                     /translation="MQPYELSLAAAAQEIRERRLSPVELVDSVLDRIERVEPHVAAYVA
                     VFAEQARRTAREAEREAARGSCRGPLHGIPVGLKDLIDVVGVSTTASSRTRAGHRAASD
                     STVAASLRAAGAILIGKTHTHEFAYGLTTPQTNNAWDRGRVAGGSSGGSAVAVACGAAT
                     FALGTDTGGSIRVPAALNGVVGLKPTYGLVPRHGVTSLSWSLDHVGPITRTVDDAALVL
                     TAIAGHDPRDPASVAVPGVDYRPRPDPDLTGVRVGVPRTYYFEHVDAEVATAVHRAIAQ
                     LEALGARLVEIDIPMTRYIQATQWGLMVPEATAYHESTLRTVPELYQADVRILLEAGEL
                     MGAGDYLRAQRARTLMRDEWAGTLKEVDVIAAPAVPMTAVPSGQETVTWPDGTVESVSD
                     AYVRLSSPANITGVPALSVPVGQDTAGMPIGMQLLGRPFAERTLLLVGHAYERTQSARP
                     LAPLP*"
     CDS             complement(3059..3324)
                     /protein_domains="PF02633"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210118"
                     /pseudo=False
                     /translation="VLLPVGSNELHGEHLPTGVDDFLAVEVCREAAVVPMAVTPSVRCG
                     SAEHHMPFGGTVTLSLPTLHSLPRDVCRSILCSADLIVARIRY*"
     CDS             3497..4071
                     /protein_domains="PF16859"
                     /protein_domains="PF00440"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210119"
                     /pseudo=False
                     /translation="MSSKQRVRPGGRSARVQASVHTAVRELMEERGREALTVPLVAQRA
                     GVTPSTIYRRWGNLQELLSDVAVERLRPDTEPEDHGDLRSDLTAWAEQFLDEMTSASGR
                     AYVRDALLGDPDGSNAGQCSAYAAEQIDVILARATDREENTPGVETVMDRIVAPMMYRI
                     LFRPAGLDAAYARRLVTELLGLPGKGDE*"
     CDS             complement(4411..5648)
                     /protein_domains="PF00144"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210120"
                     /pseudo=False
                     /translation="VALATWMGAVLVGCSDDGQDGAGPAAGRGTAHTAAAGRLSVLAQK
                     AADTGSLGVIVRIDRGDGKPVEIARQAAWTKDDHRLAVGDRFRVGSNTKTLTATLVLQQ
                     VAEKRIGLDDTVEEWLPGLVKGGGRITVRMLLNHTSGLDDFLLTPEFLPSLTGQEQRTW
                     RPEELLATTPEQDPPTGPGEKYSYSNANYEALGLILEKATGSSLAELIEQRITKPLGMK
                     DSFLATDAAWHAGKRHATGYEPDAKRLKDLLSGTVDLPEGVGFAGPERPGDNIDTTAID
                     PSWAWAAGGMVSTAQDWQRFLTALTSGRLLPEAQMEQMRTTVDAPEEGGGYGLGLMKVD
                     TPCGTVWGHTGGLPGYSSEIYTDTTGTRSVAVLTVTNFGVKERKAATANKALVDAATCQ
                     MLGNPQPSNRTTA*"
     CDS             complement(5920..6584)
                     /protein_domains="PF00072"
                     /protein_domains="PF00196"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210121"
                     /pseudo=False
                     /translation="VAEQISVLVVDDEPVIRAGLSAILDSQPGITVAGTADDGENAVEA
                     CARLRPDVLLMDIRMPRRDGLWALAELKRRGLTGPGRSRVIMLTTFDVDEYVDDALAAG
                     ASGFLLKNSSYEELTGAVRAAAAGHSTLSPAVTHRIIEGHLRGRRRPSDHELARLRTLT
                     EREADVLRLIRDGLSNAEIADRLVVSLHTVKTHVSRVLTKTGCQSRAQAAVLARNTLS*
                     "
     CDS             complement(6578..7758)
                     /protein_domains="PF07730"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210122"
                     /pseudo=False
                     /translation="MDRRWHGWGTDAGLLVLTFLPALLSQPYVDASGPAWASLTAYEAV
                     GVVVLLLRRRLPATAFVVGFGALLAALVWSAGEGAKLSPLVFLPPAVLLYSLGHHGASW
                     RRTVSAVLGVAVLGVAGLWLNRMTTDSSDFRGGLDVLAALAPMPLAWVMGFAARTRQAL
                     LAAAEQRAADARRAQALEAAQAAQRERARIAGEMHDVVAHSLTLLVVHAETLRARGGEL
                     PDWARAQVDGLAAAGRQSSGELRDLLRMLRDPSDAVPLRPTPDLAELDTLLDGHRALGG
                     RVELMMDLAPEAVPGAVQLAGYRVVQEALVNARRHAPGAPVRVTVASVAGRLRCEVVNG
                     PAARRGAADAGIGLGLVSMDDRVGALGGDLTAGPTRDGGFRVVATMPLECAGG*"
     CDS             complement(7779..7996)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MLNEDRGDHGRALDVVVPAFDSALILVVGQGLSCVRPVSGSGGRS
                     VAARWHSASAHAPTALALSASNLREDQ"
     CDS             complement(8123..8931)
                     /protein_domains="PF01925"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210123"
                     /pseudo=False
                     /translation="VLTSFFILLLFGCLTGVTTVLFGFGGGFVTVPVVYGLWSVTARSG
                     ADAMHVAVATSTAVMVVNSVFATLTQWRQSRLRREYLWPLAAFVTAGAVAGAFAATRIG
                     DTALRVLFAAYLLVTIADSLLRKGFLSVPQTSEPRPLSRPARTLGGVGIGAVAACLGVG
                     GSVMTVPILRRRGLPMAEATAMANPLSVPVAVVGTAVYALAAPALQARAGRLGYVDLLA
                     CAALLGGSLPTIALTRRIAARVADRVHSVAYVVLLVTVLLVMLAAGT*"
     CDS             complement(9132..9841)
                     /protein_domains="PF12697"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210124"
                     /pseudo=False
                     /translation="VFLHYWGGSARTWDLVVDRLAGRDVLTIDFRGWSRSSALPGPYTL
                     GQLADDTLAVLADSGVTDYVLVGHSMGGKVAQLVAATRPAGLRGLVLVGSGPAKPAAQV
                     TPEYQEALSHAYDSAESVAGARDHVLTATELPASVKARIVTDSRTVADAARTEWPLHGI
                     AQDITEHTRRVGVPALVVAGEHDQVEPAGVLRDNLVPYLSHPDFVVVPRTGHLIPLEAP
                     ADLVDAITAFAPAT*"
     CDS             10020..10846
                     /protein_domains="PF12833"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210125"
                     /pseudo=False
                     /translation="VSVIRHMTHQPAGRRDASVETMTFGRLRELNDGGTQRADFHVLAV
                     IDAGPGSVTVDFRRHPLQDRSAVWIPPGAVHRWDDIADVAGHLVLFVPTAPVTRATREL
                     VASPDPAAQWIIPDADWPFVDTARRHLLLEASAPPGDSRTELPDILLSALITRLHPPHA
                     EARFTPPVFRLFRSSVEAHFRQHHDAGYYARALGYAPRTLSRAVQQATGRTAKAYIVER
                     ITLEAKRLLAHDRVTAARCADLLGFPDASNFSVFFHKATGQRPGAWQARVAAE*"
     CDS             10979..11859
                     /protein_domains="PF12833"
                     /protein_domains="PF02311"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210126"
                     /pseudo=False
                     /translation="VRNVRVDEVDALDRAVLAIGTDYPPGHLLPYHEHRRAQVLYAATG
                     VMELATAQGTWTVPTDRAVLIPAGTRHQVTMLKVSTRSLYIEPAAVPWFPGHCRVVEVS
                     ALLRELLLAAVDMAPRYPEHGRNAALVDLLLHELAHLAPLPLDIPLPADPRLRRLCETF
                     LRSPDIHDPPARWAAALSVSERTLGRRFRSATGLSFAQWRRRACIVHSLRHLAAGVPVT
                     RIAVELGYDSPAAFTTAFRALLGRPPSAYRSEAPPVSREPRQQEGRWSSCGKRDFHWSG
                     STPSGWVAQRRS*"
     CDS             complement(11767..16313)
                     /protein_domains="PF00656"
                     /protein_domains="PF00400"
                     /protein_domains="PF00400"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210127"
                     /pseudo=False
                     /translation="VTERWGDLAGPDCRAVVVGTGQQSAGERGGPDGGVRLAGLPSAAH
                     TARELARVLRERCGMAAGRVTELIDPAGPTEVLAALRDAVEAAAGGVVLFCFTGHGLLG
                     PGGQLYLATAATARPDDTVTAVPYAEVRHLLGDASARAVVVLDCCFSGRAAAAPSDAHR
                     DPYATARPPGSFLLASASGYAASFAPVDQPYTLFGGELVRLLAEGDPSGPRWLTLLDVY
                     RILDRRFQGGPARPYAEGVGRATDLVVARNVCSPAPLEEADVPAGGGPCPYPGMRPFLP
                     EQRHLFFGREEPARELLDRVTHGDGPVVLVGASGAGKSSLLRAGLVAGLEERGTGPVLL
                     VEGPGARPFRTLVERWARAVDRPFEEVEREVGAGRFGTGGPEVLVIDQLEELFTDCVDP
                     EERELFVRAVSGAGAATGPRIVLGLRADFYGLCMRDARLARMLRAGQFTVPAMSDEELI
                     AAIERPAEHAGLRLEDGLAGHLLHELRREAPGGEADSVALPFLAHALQQTWARRRGTQL
                     TFAGYEAAGGIRGSVARVADELYDALEPAGRERLRELLLRMVTLVDTEGRAARRRLPVP
                     EAAGEAEREDRELLDRLADARLVVLDRGEAQLCHDSLLHGWPRLRDWIRDDRVRLLVLR
                     RVGDAADSWAEADREKSALYRGDQLAAARQELRGEGPRLRPVERDFLAASDRAERRARR
                     IRTGVGAVVAALAVLASLLAVRADRAQRDAEARESVAVAEQLAAQADTMRERDPQTALR
                     LSLAAYRTADTGATRSSLYAAYLSRPQVDLRGDVRQPVVDLAYGPGGRVLATSQRTGVV
                     RLWDLGRPNAPVRGAALERLHGTAPLAFSPRSPLLAALSTDALTLWDATDPVHPKRLGS
                     LKLAENQSYSLAFSPDGRTLAAGGENGRLRLWDLSVPSAPRPLYDRKVARAHLMAVAFN
                     RDGRFLAAGNGVSEDAAGKERPAEVRLWDVRDPARPALLTTATADSVMAVAFHPKRDTL
                     VATGGESAMAWWTVRDGGRRLARIRPTDSFEGGWGYGGNLPSLDFSPDGSALAAAYGAR
                     PGKATIRRVAERDGPEQLSSVNERGSVPSGEPTQAVAWSPDGAYLAAGDVGGNVRLWPE
                     HTPGLALRGTLAGGDPGAHPYTRDGRFVLTREAVVGSPHSVARVWDMSGADTVRGRSPK
                     LRFTVPRPWEAQYFLPGRDRPVLLAHRWTEDTDEHAFRIWDLGGDGPPVAGAEIPVRSP
                     NVRTAVSKDGRLLVVGTSSDPTAAIWDLSDPLRPVRRAVIPVTPSAEPESMLFMGPGAL
                     ATVEAEGRGRGLDLRLWDLSDPVHPFRVPEPLKGAAVARATYVHSLRLLLTDGDAQTAR
                     LYDLRDIRHPKSVGTLPAASGGYTPVGGGLLATTLQDGTVRFYDIRDPRHPVLRHAQRL
                     DREVTAITPDLDGGRVLTAEPYRVWDVAADGSWRIPAFATLQGVRRVDLLPGRTPFMTV
                     VADARSSDRGPEYTYLLDRDPRKVYDRLCATHPLGVEPDQWKSLFPQLDHRPSC*"
     CDS             complement(16318..16709)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8210128"
                     /pseudo=False
                     /translation="VHIALEVGGTSEDAYELRQWLRGDPELRPAVVPLVPASPAPGSMG
                     AFGSVIELLLQPGGLTVTLAAGVVAWLQTRRGSQTVTITKPDGTQVVVTSQGVRGLTPE
                     SSGELALEVARALEEPARQPSGPENP*"
     CDS             complement(16902..17062)
                     /protein_domains="PF08031"
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_8210129"
                     /pseudo=False
                     /translation="VNFLGPETPDQVAHSYGPNTRRLPAVKSAVDPDSVFAATPLPLGT
                     ADAGSPPV*"
ORIGIN
        1 tcagcggagg gggcggttgc gcggactgct gcggggcctc gtccgggttc gtgacacggc
       61 gagtgctgtg agggccgccg cggcgaggag cgcggcgacg gcggcgtagg cgtgcgaggt
      121 ggtcctgagc ccgtagtgct gggtggcggc ccccgcggcg acggcgggca ggctcatgga
      181 gaggtagctc agaacgtagt aggcggccag cgtcgcggcg cggtaccgct cgtcgagcga
      241 ggccaggagc atacgaagta cgccttggga gacggcgccg aaggccactc cggccagggc
      301 cgcgccgccg tggacggacg gcagtccgac gccgtgcaga ccgctcaggg tcaggaccgc
      361 ggcgggcagg acgcagaggc atccgccgat cgcggtggtg aggggatcgg cgcggcgcag
      421 gacccacatg gtgagtgcgg ccgcggcgct gagggtgaag aagaccatgc cgagggccgc
      481 ctgcggggcg ttgggggcca ccaggcgcac gagggccggc ccgagggagg agtagaagcc
      541 gcccagtgcc cagatcgcga cgatggcggt gccggtggtc agcagggtgc ggcgcaccgc
      601 gggaggcaca ccgagtcgcg ggcgcagcga tcgcagggcg cctgcccggc gggcgactgt
      661 ctccgtggtg aaggtgacgg cgatcgcctg ggcggcgaac agggctgcca tcagcgcgta
      721 gacggtgacc gtgggggccg gggcgaagcg gacgagaagg gtggagacga gaacgcccgc
      781 ggccatgccg gcgaccgggg cgatggtgtt ggtcagggcg gagcgaccgg gatgccgcgg
      841 gctttccagg tcgaggagag ccgcgcccgc ggcgctggtg gctgcgccgg tggccactcc
      901 ttgcaggagg cgggccgctg tcagggaacc cgcgccgtcc gctgaggcga ggagaaccat
      961 ggcgacggcc tgcgcgccca gagcgcccgc caggacggga cgccgtccca ggcggtcgga
     1021 gagccctccg gtggtgagaa gggccgacag cagcgccagg gagtacgcgc tgaagaccac
     1081 cgtgacggcg agcgccgaaa ggccccactg gtcctgatag agggggtaca gcggtgtcgg
     1141 ggcactggat gccgccagga gggccacgag tacggacgcg tccagaccga aggaggcggc
     1201 acggttcttc ccgtgggcgc ggctgccccc gacagggcgg tgcgagagtg ggccggacac
     1261 gacgtcggac atgaaacatc ccccttaaag caatgtgttt gccttaaggc acgatagggc
     1321 ctacagtcga gctaaagcaa accattagct tttgtcgtgg tgtgcctcgt cgctccattc
     1381 aggctcgatc aggggagaat ccatgtcctc cgccggactc acaccgcccg aggccgcccg
     1441 ctgggccgcc cgtgccgggc ttccgctgcc cgatgaccgc cactgcgtgg tcgcggccac
     1501 cgccgaccac atccactccg tcgtcggggt cctgcgcgag ctgaacttcg gtgacacccc
     1561 gcccgccggt gccttccgtg cggaacagga gaagcacgat gcagccgtat gagttgtccc
     1621 tcgccgccgc cgcgcaggag atccgggagc gacggctgtc ccccgtcgag ctggtcgact
     1681 cggtcctcga ccgcatcgag cgggtggagc cgcacgtcgc ggcctacgtc gcggtttttg
     1741 ccgagcaggc ccgccggacc gcccgtgagg ccgagcgcga agccgcccgg ggctcctgtc
     1801 gaggccctct gcacgggatc ccggtgggcc tcaaggacct gatcgatgtc gtcggcgtgt
     1861 ccaccacggc aagctccaga acccgggccg gtcaccgcgc ggcctccgac agcacggtcg
     1921 ccgcgagtct gcgggcggcc ggcgcgatcc tgatcggcaa gacgcacacc cacgagttcg
     1981 cctacgggct gaccaccccg cagaccaaca acgcctggga tcgcggcagg gtcgccggtg
     2041 gctccagcgg cggctccgcc gtcgccgtgg cctgtggtgc ggcgacattc gccctcggca
     2101 ccgacaccgg cggatcgatc cgggtgcccg ccgccctgaa cggggtggtc ggactcaagc
     2161 cgacgtacgg actcgtgccc cgccacggcg tcacgtcgct gtcctggtcg ctcgaccacg
     2221 tcggcccgat cacccgcacc gtcgacgacg cggccctggt cctgaccgcc atcgccgggc
     2281 acgacccccg cgaccccgcc tcggtggccg tccccggcgt cgactaccgg ccgcgccccg
     2341 acccggacct gacgggagtg cgcgtcggcg tgcctcgcac ctactacttc gaacacgtcg
     2401 acgcggaagt cgcgaccgcc gtccaccgcg ccatcgcgca gctggaggcg ctcggcgccc
     2461 ggctcgtcga gatcgacata ccgatgaccc gctacatcca ggccacccag tggggcctga
     2521 tggtgccgga agccaccgcg taccacgaaa gcaccctgcg taccgtcccc gagctgtacc
     2581 aggcggatgt ccggatcctc ctggaggccg gcgagctgat gggcgcgggc gactacctgc
     2641 gggcgcagcg cgcccggacg ctgatgcgcg acgaatgggc cggcaccctg aaggaagtcg
     2701 acgtgatcgc cgcccctgcg gtcccgatga ccgcggtccc gtcgggccag gagaccgtca
     2761 cctggcccga cggcacggtc gagagcgtct ccgacgccta cgtgcgcctc tcctccccgg
     2821 ccaacatcac aggagtgccc gcactctccg tcccggtcgg ccaggacacg gcaggcatgc
     2881 ccatcggcat gcagttgctc gggcggccct tcgccgagcg gacgctgctg ctggtgggcc
     2941 acgcctacga gcggacgcag tccgcccgac cgctcgcccc cctcccgtga gggcggtgtg
     3001 ggggccgggc cgaaaagttc cggcccggcc cccacacatc gctcggctcc gtcgggatca
     3061 gtaccggatg cgcgcgacga tgagatcggc ggagcacagg atcgagcggc acacatcccg
     3121 cgggagcgag tggagggtcg gcagcgacag ggtcacggtg ccgccgaagg gcatgtggtg
     3181 ctcggccgag ccgcaccgca ccgacggggt gacggccatg gggacaacgg cggcctcgcg
     3241 gcatacctcc acggcgagga agtcgtcgac accggtcggc aggtgttcac cgtgcagctc
     3301 gttcgagccc accggcagca gcacgacggc gtcacgctgc gccagttcgc gcagctccga
     3361 agcgttcaga cgggttccag cgattctcgg gcatggccaa gaacccttcc tgagccgtgg
     3421 aagcgaatgc tcggcttcag tgagcccggg tatcgaggcc cgctaaacgc aaggactgtg
     3481 ctttaggctg gcgcgatgag cagtaagcaa agggtccgcc ccggcgggcg cagcgcacgc
     3541 gtccaggcgt cggtgcacac cgctgtacgg gaactcatgg aggaaagggg ccgcgaggcg
     3601 ctgaccgtcc ccctggtcgc ccagcgcgcc ggagtcaccc cgtcgaccat ctaccgacgc
     3661 tggggaaacc tgcaggaact gctctcggac gtcgcggtgg agcggctgcg acccgacacc
     3721 gaaccggagg accacggcga cctgcggtcc gacctcacgg cgtgggccga acagttcctc
     3781 gacgagatga cgtccgcctc gggccgcgcc tacgtccgcg acgccctgct cggcgacccg
     3841 gacggcagca acgccggcca gtgctcggcc tacgcggccg aacagatcga cgtcattctc
     3901 gcccgggcca ccgaccgcga ggagaacact cccggcgtcg agacggtcat ggaccgcatc
     3961 gtcgccccca tgatgtatcg catcctcttc cgcccggccg ggctcgacgc cgcgtacgcc
     4021 cgccggctcg tgaccgagct cctcggccta cccgggaagg gcgacgagtg accgggtgac
     4081 tgttccccgt cgcctgcgga agcgctcgcg cggccccgtc ccgacggacg ctccggcgac
     4141 gtcgcccgtc accccgggag acgggcacga gggctccggg gtccggcagg cggcgaacgc
     4201 gccggcggtc ggctcgccac gcgcagggcg aagggccacc acgccgcgtc ggctgcgaca
     4261 caccgctcga cacggtctac ggcacggatg cgcaggatgt gttcgcgggc cgccggggcg
     4321 tgggcatcgg gtgctcctgg ggacgtgcca ccgcgttggc gcttcccgca gtgccgcacc
     4381 gcccgttccc ggaccgggtg cggtgcccgt catgcggtcg tcctgttcga gggctgcggg
     4441 ttgcccagca tctgacaggt ggccgcgtcg acgagggcct tgttcgcggt cgcggccttc
     4501 ctttccttga cgccgaagtt cgtgacggtg aggaccgcga cgctacgggt gccggtggtg
     4561 tcggtgtaga tctcactgga gtagccgggc aggccgccgg tgtgccccca gaccgtgccg
     4621 cagggcgtgt ccaccttcat caggcccaga ccgtaacctc cgccctcctc gggggcgtcc
     4681 acggtggtgc gcatctgctc catctgggcc tcgggcagca accggccgga cgtgagcgcg
     4741 gtgaggaagc gctgccagtc ctgcgcggtg gagaccatac cgcctgccgc ccacgcccag
     4801 ctcgggtcga tggcggtggt gtcgatgttg tccccgggac gttcgggccc ggcgaatccg
     4861 acgccctcgg gcaggtccac ggtcccggaa aggaggtcct tcaggcgctt ggcgtccggc
     4921 tcgtagccgg tcgcgtggcg tttcccggcg tgccaggccg cgtccgtggc caggaacgag
     4981 tccttcatgc cgagcggctt ggtgatcctc tgctcgatca gctctgccag gctgctcccg
     5041 gtggccttct ccaggatcag cccgagggcc tcgtagttgg cgttgctgta ggagtatttc
     5101 tcgccgggcc cggtcggcgg gtcctgctcg ggagtggtgg cgagaagttc ctccggcctc
     5161 catgtgcgct gctcctgacc ggtgagcgag ggcaggaact cgggcgtcag caggaagtcg
     5221 tccaggccgc tggtgtggtt gagcagcatc cgcacggtga tgcgcccacc gcccttgacc
     5281 agtccgggca gccactcctc gaccgtgtcg tcgaggccga tccgcttctc ggcgacctgt
     5341 tgcaggacga gcgtcgcggt gagcgtcttg gtgttggacc cgacccggaa ccggtcgccg
     5401 acggcgaggc ggtggtcgtc cttcgtccag gcggcctggc gggcgatctc gacgggcttc
     5461 ccgtcgccgc ggtcgatccg gacgatgacg ccgagggagc cggtgtcggc cgccttctgc
     5521 gcgaggacgc tcaggcgccc ggcggcagcc gtgtgcgccg tcccccgccc ggccgcgggt
     5581 ccggccccgt cctgcccgtc gtccgagcag ccgacgagca ccgcgcccat ccaagtggcc
     5641 aacgccacgg tgagcgcccc tcgaagaacc cggtgacggc gagacggagt gtgtgcggac
     5701 atggcagttc ccttcggcgc gtggcagttg ctcgtgcgtg gagggatgtg gcgttcaccc
     5761 cggtgaacgc gttcgaaggc tccgcgcaca gcgaccattc agccagcggc gcgcccccgg
     5821 cacatcgctc gatggagggc ttccctccgg cacggggtca ctccaaggaa tgaccccgcg
     5881 gcagacggcg cctcgccgcc cagcccaccg aggacgggtc aggacaaggt gttcctggcc
     5941 agcaccgcag cctgcgccct gctctgacag ccggtcttcg tgagcacacg gctgacgtgt
     6001 gtcttcacgg tgtgcaggct caccacgagc cggtcggcga tctcggcgtt gctcaggccg
     6061 tcgcggatca gacgcagcac gtcggcctcc cgctcggtaa gggtcctcag ccgcgccagc
     6121 tcatggtcgc tggggcgccg ccggccacgg agatggccct cgatgatccg gtgggtcacc
     6181 gcggggctca gtgtgctgtg tccggccgcc gcggcgcgta cggccccggt cagctcctcg
     6241 tacgaactgt tcttcaggag gaagccggac gccccggcgg cgagcgcgtc gtcgacgtac
     6301 tcgtccacgt cgaacgtggt cagcatgatc acccggctgc gccccggccc ggtcagtccg
     6361 cggcgcttga gctcggccag tgcccacagg ccgtcgcggc gcggcatacg gatgtccatc
     6421 agcagcacat ccggccgcaa ccgtgcgcac gcctcgacgg cattctcgcc gtcgtccgcg
     6481 gtacccgcca cggtgatgcc cggctggctg tccaggatgg cgctcagccc ggcgcggatg
     6541 accggctcgt cgtccaccac gagcacactg atctgctcag ccaccggcac actccaacgg
     6601 catcgtggcc accacgcgga agccgccgtc gcgggtcggg cccgcggtga gatcgccccc
     6661 cagcgcaccc acgcgatcgt ccatgctcac cagaccgagt ccgatgcccg catcggccgc
     6721 gccacgccgc gcggcggggc cgttcaccac ctcgcaccgc aaccgtcccg cgaccgacgc
     6781 gaccgtcacc cggaccggcg ccccgggcgc gtgccgacga gcattgacca gtgcctcctg
     6841 cacgacacga taaccagcca gctgcaccgc tcccggcaca gcctccggcg cgagatccat
     6901 catcagctcg acccttcctc ccaaggcacg gtggccgtcc agcaacgtgt ccagttcggc
     6961 gaggtccggc gtcggccgga gcgggaccgc atccgaggga tcgcgcagca tccgcagcag
     7021 atcccgcagc tcaccgctgc tctgtcggcc cgccgccgcc agcccgtcga cctgggcacg
     7081 agcccagtcg ggcaactcgc caccgcgggc ccgcaaagtc tccgcgtgca cgacaagcag
     7141 ggtcagcgag tgcgcgacca catcgtgcat ctcaccggcg atccgcgccc gctcccgctg
     7201 cgcggcctgc gccgcctcca gagcctgcgc ccggcgtgcg tcggcggccc gctgctccgc
     7261 cgcggccagc agcgcctgcc gcgtccgtgc ggcgaacccc atcacccagg ccagcggcat
     7321 cggggccagc gcagcgagaa cgtccagacc gccccggaag tcactggaat cggtcgtcat
     7381 ccggttcagc cacagacccg ccacgcccag cacggcgacg cccagcaccg ccgacaccgt
     7441 ccgcctccag ctcgcaccgt gatggcccag gctgtagagc agcaccgccg gcggcaggaa
     7501 gaccagcggt gacagcttgg ccccctcgcc cgcactccac accagcgccg ccagaagagc
     7561 cccgaaaccc acgacgaagg cggtggccgg cagccgccgc cgcagcagca ggaccaccac
     7621 gccaaccgct tcgtacgcag tgagcgacgc ccaagccggt ccggaggcat ccacgtacgg
     7681 ctgcgacaga agcgcgggca ggaacgtcag cacgagcaac ccggcgtcgg tgccccaccc
     7741 gtgccacctg cggtccatca ctctcatccg ttcgacacta ctgatcttct cgtaagttcg
     7801 aggcggagag cgcgagggcg gtgggggcgt gtgccgaggc actgtgccaa cgggcagcca
     7861 ccgaacgccc gcccgagccg gagaccgggc ggacgcagga caggccctga cccacgacga
     7921 ggatcagggc ggagtcgaac gcaggcacca cgacgtcaag ggctcgcccg tggtcgcccc
     7981 ggtcttcgtt cagcacgacc gacgcgccgc cgcctcggtc ctgcgccggt cgctccccgc
     8041 acgtgtacga cgatgctgtt cctcgccctc ggatgcgcac gcgtccgcag gctgcccccg
     8101 aagacctcgc gacgggagtt cctaggttcc cgccgccagc atgacgagca gcacggtcac
     8161 cagcaggacg acgtaggcga cggagtgcac ccggtccgcg acgcgggccg cgatgcggcg
     8221 ggtgagggcg atggtgggca gtgagccgcc cagcagcgcg gcgcaggcga ggaggtcgac
     8281 gtagccgagc cgtccggccc gggcctgcag ggcgggggcg gccagggcgt agacggcggt
     8341 gccgaccacg gcgacgggca cgctgagcgg gttcgccatc gccgtcgcct cggccatcgg
     8401 caggccccgg cggcgcagga tcggcacggt catcacgctg ccgccgacgc ccaggcaggc
     8461 ggcgaccgcg ccgatcccga ccccgcccag cgtcctggcc ggccggctca gcggtcgcgg
     8521 ctccgaggtc tgcggtacgg acaggaatcc cttgcgcagc aggctgtcgg cgatcgtcac
     8581 cagcaggtac gcggcgaaca gcacccgcag cgccgtgtcg ccgatccggg tcgccgcgaa
     8641 cgccccggcc accgcgccgg ccgtcacgaa cgccgccagc ggccagaggt actcccggcg
     8701 cagccggctc tgccgccact gtgtcagtgt cgcgaagacc gagttgacga ccatgaccgc
     8761 cgtcgacgtc gccaccgcca cgtgcatcgc gtcggcgccg gagcgcgcgg tgacgctcca
     8821 caggccgtag acgacgggga cggtgacgaa gccgccgccg aacccgaaga gcaccgtggt
     8881 gacaccggtc aggcagccga acagaagcag gatgaagaag gaggtcagca ccgcatcgac
     8941 gctacggacc cggccgtctg gcgggccatc gaatgagcgc cggagatttg cgcgtatccg
     9001 acaccctcca cggcggcagg cggacgggga ggcgaccggt gggtgacggg cgccgatcac
     9061 cacgtcgccc cgtaaccccg ggcggccggc tcggggcggg gcgcggcccg tcgtcgggcc
     9121 gcggggacgg tcaggtcgcc ggcgcgaacg cggtgatggc gtcgacgagg tcggccgggg
     9181 cttccagcgg gatcaggtga ccggtgcggg ggaccaccac gaagtcgggg tgggagaggt
     9241 agggcaccag gttgtcgcgg agcacgccgg ccggctccac ctggtcgtgt tctccggcga
     9301 cgacgagagc gggcacgccg accctgcgcg tgtgttcggt gatgtcctgc gcgatgccgt
     9361 gcagcggcca ctcggtgcgg gcggcgtcgg cgacggtccg cgagtcggtc acgatccgtg
     9421 ccttgaccga cgcgggcagc tcggtcgcgg tgaggacgtg atcccgtgcc ccggccacgg
     9481 actcggcgga gtcgtaggcg tgcgacaggg cttcctggta ctcgggagtg acctgtgcgg
     9541 cgggcttcgc cggtccggaa ccgacgagaa ccaggccccg caggccggcg ggccgggtgg
     9601 ccgcgaccag ctgtgcgacc ttgccgccca tcgaatgccc caccaggacg tagtcggtga
     9661 cccccgagtc cgcgagcacg gcgagcgtgt cgtcggcgag ctgaccgagc gtgtagggac
     9721 cgggcagagc gctcgaccgg ctccacccgc ggaagtcgat cgtgagcacg tcacggcccg
     9781 ccaggcggtc gacgacgagg tcccaggtgc gggcggaacc gccccagtag tgcaggaaca
     9841 ccagagtcgg tccggtcccc ggccgatggt cgtaagtggg cagtagcgtc tgctgcgtcg
     9901 tatccacgat ggctcttcca atcgatgctc cgggcgattg ccccgtgcat ccattgaaac
     9961 ttccgcaccc ggacggggca tcggcgtgac tggtcacccg atggtggaaa ctggacacgt
    10021 gagcgtgatc cggcacatga cccaccagcc cgcgggacgt cgcgacgcct cggtcgagac
    10081 gatgacgttc ggccgccttc gcgagctgaa cgacggcggc acgcagcgcg ccgacttcca
    10141 cgtcctcgcc gtcatcgacg ccggacccgg ctcggtcacc gtcgatttcc gccgccaccc
    10201 gctccaggac cggtccgcgg tgtggatccc acccggcgcc gtgcaccggt gggacgacat
    10261 cgccgacgtg gcaggtcacc tcgtgctgtt cgtgccgacc gcgccggtca cccgcgccac
    10321 ccgagaactg gtcgcctctc ctgacccggc cgcgcagtgg atcatccccg acgccgactg
    10381 gcccttcgtc gacacggcgc gcaggcatct cctcctcgaa gcatccgccc cgcccggtga
    10441 ctcccggacg gagctgcccg acatcctgct ctccgcgctc atcacccgac tgcacccacc
    10501 gcacgccgaa gcacggttca cccctccggt gttccggttg ttccgctcca gcgtcgaagc
    10561 gcacttccgg caacaccacg acgccggcta ctacgcccgt gcgctgggat acgcgccccg
    10621 caccctctca cgagcggtgc agcaggccac cggccgcacc gcgaaggcgt acatcgtcga
    10681 acggatcacc ctggaagcca aacggctcct cgcacacgac cgcgtcaccg ccgcccgctg
    10741 cgccgacctg ctcggcttcc ccgacgcatc caacttctcg gtgttcttcc acaaggccac
    10801 aggccaacgc ccgggcgcgt ggcaggcgag ggtggccgcc gagtgaggag gcggccacaa
    10861 gaacactcac ctctgtgtta cacggcgtca cacccccgtg atcaccggaa cctcgtgctc
    10921 gcctccctgt cccggtgtcc caccgtgagt acccgcgtca cctcttagtc tggccgtgtg
    10981 cgcaacgtcc gcgtcgacga ggtcgacgcc ctcgaccgtg ccgtcctggc catcggcacc
    11041 gactacccgc ccggccatct gctgccctac cacgagcacc gccgggccca ggtcctgtac
    11101 gccgcgaccg gcgtcatgga gctggcgacg gcacagggga cgtggacggt gcccaccgac
    11161 cgcgcggtgc tgatcccggc cggcacccgg caccaggtca ccatgctcaa ggtcagcacc
    11221 cgcagcctct acatcgagcc cgcggccgtg ccgtggttcc ccggccactg tcgggtcgtc
    11281 gaggtctcgg cactgctgcg cgaactcctc ctggcggccg tcgacatggc gccgcgctac
    11341 ccggagcacg gccgcaacgc ggccctggtc gacctgctgc tgcacgaact ggcccacctg
    11401 gcgccgctgc ccctcgacat cccgctgccc gccgaccccc ggctgcggcg gctgtgcgaa
    11461 accttcctgc gcagccccga catccacgac ccgcccgccc gctgggccgc ggccctgagc
    11521 gtcagcgagc gcaccctcgg ccgtcgtttt cgcagcgcca ccggcctgag cttcgcccag
    11581 tggcggcggc gcgcctgcat cgtgcactcc ctgcggcacc tggccgcggg cgtaccggtc
    11641 acccggatcg cggtcgagct cggctacgac agccccgcgg cgttcaccac ggccttccgc
    11701 gcgctgctcg gccgtccgcc gagcgcctac cgctctgagg cccccccggt ttcgcgcgag
    11761 ccccgtcagc aggagggtcg gtggtcgagc tgtgggaaga gggacttcca ctggtccggc
    11821 tcgacgccca gcgggtgggt cgcgcagagg cggtcgtaga cctttcgcgg atcgcggtcg
    11881 aggaggtacg tgtactccgg gccgcggtcg ctcgaccggg cgtccgccac caccgtcatg
    11941 aacggcgtcc gccccggcag caggtccacc ctccgcacgc cctgaagggt ggcgaaggcc
    12001 gggatgcgcc agctgccgtc cgcggcgacg tcccagacgc ggtacggctc ggcggtgagc
    12061 acgcggccgc cgtcgaggtc gggcgtgatg gcggtgacct cccggtcgag gcgctgggcg
    12121 tgccggagca ccgggtggcg cgggtcgcgg atgtcgtaga accgtacggt gccgtcctgg
    12181 agggtcgtcg cgagcagacc gccgccgacc ggggtgtagc cgcccgaggc ggccggcagc
    12241 gtccccacgg acttcgggtg ccgaatgtcc cgcaggtcgt acagcctggc ggtctgggcg
    12301 tcgccgtcgg tgagcagcag ccgcagggag tggacgtagg tcgcccgggc gaccgccgcg
    12361 cccttcagcg gctcgggtac gcggaacggg tgcacggggt cgctcaggtc ccacaggcgc
    12421 aggtcgaggc cccggccgcg gccctcggcc tccacggtcg cgagcgctcc cgggcccatg
    12481 aagagcatgc tctcgggctc ggccgagggc gtcaccggga tcaccgcgcg ccgcaccggc
    12541 cggagcgggt cgctcaggtc ccagatcgcg gccgtcggat ccgatgaggt cccgacgacc
    12601 agcagccggc cgtccttcga gacggcggtg cgcacgttcg gcgagcgcac tgggatctcg
    12661 gcgcccgcca ccggcggtcc gtcgccgccg aggtcccaga tccggaaggc gtgctcgtcg
    12721 gtgtcctcgg tccagcggtg cgcgagcagc accggccggt cgcggccggg caggaagtac
    12781 tgcgcctccc acggcctggg cacggtgaac cgcagcttcg gcgaccgccc gcgcacggtg
    12841 tccgccccgc tcatgtccca gacgcgcgcc acgctgtgcg gggagccgac gaccgcctcg
    12901 cgggtgagga cgaaccggcc gtcccgcgtg tagggatggg cccccgggtc cccgccggcg
    12961 agggtccccc ggagggcgag cccgggcgtg tgctcgggcc agaggcgtac gttgccgccg
    13021 acgtcgcccg ccgcgaggta ggccccgtcg gggctccagg ccaccgcctg ggtgggctcg
    13081 ccgctcggca ccgagccgcg ttcgttcacc gaggacagct gctccggtcc gtcgcgttcg
    13141 gcgaccctcc ggatggtggc cttgccgggc cgggcgccgt acgcggcggc gagggcggag
    13201 ccgtcggggc tgaagtcgag cgagggcagg ttgccgccgt aaccccatcc gccctcgaac
    13261 gagtccgtcg gtctgatccg ggcgagccgc cgtccgccgt cccggaccgt ccaccaggcc
    13321 atcgcgctct cgccgccggt cgccacgagc gtgtcccgct tcgggtggaa ggccaccgcc
    13381 atcaccgagt cggccgtcgc ggtggtgagg agagccgggc gggccgggtc gcggacgtcc
    13441 cacagccgca cctcggccgg gcgctccttg cctgcggcgt cctcgctcac accgttgccg
    13501 gcggcgagga aacgcccgtc acggttgaac gccacggcca tcaggtgggc ccgggcgact
    13561 ttcctgtcgt acagcgggcg cggagcggac ggcacggaga ggtcccacag ccgcagccgc
    13621 ccgttctccc cgcccgccgc cagcgtccgc ccgtccgggc tgaaggcgag gctgtacgac
    13681 tggttctcgg cgagcttcag gctcccgagc cgcttcgggt gtacgggatc ggtcgcgtcc
    13741 cacagcgtca gcgcgtccgt gctcagcgcg gcgagcagcg gggagcgcgg ggagaaggcg
    13801 aggggcgcgg tgccgtgcag gcgctccagg gcggcgccgc gcaccggcgc gttcggccgg
    13861 cccaggtccc agaggcggac gacgccggtg cgctggctgg tggcgaggac gcggccaccg
    13921 ggcccgtacg ccagatcgac caccggctgc cggacgtcac cgcgtaggtc gacctgtggc
    13981 cgggagaggt aggcggcgta gaggctggag cgggtggcgc cggtgtcggc ggtcctgtac
    14041 gcggcgagac tcaggcgcag cgcggtctgc gggtcgcgct cgcgcatggt gtcggcctgc
    14101 gcggccagct gctcggcgac ggcgacgctc tcgcgggcct cggcgtcgcg ctgggcgcgg
    14161 tcggcccgca ccgcgagcaa ggaggcgagg acggcgagcg cggccacgac cgccccgacg
    14221 ccggttcgga tccggcgggc gcggcgctcg gcccggtcgc tggcggcgag gaagtcccgc
    14281 tccacgggcc ggagccgggg gccctcgccc ctgagttcct gccgcgccgc ggccagctga
    14341 tcgccccggt acagggcgct cttctcgcgg tccgcctccg cccagctgtc ggccgcgtcg
    14401 cccacccggc gcaggacgag caaccgcacc cggtcgtcgc ggatccagtc gcgcagccgg
    14461 ggccacccgt ggagcagcga gtcgtggcac agctgggcct cgccccggtc gaggacgacc
    14521 aggcgggcgt ccgcgagccg gtcgagcagc tcgcggtcct cccgctcggc ctcgcccgcc
    14581 gcctccggga ccgggaggcg gcggcgggcg gcccggccct cggtgtcgac caacgtcacc
    14641 atgcgcagca ggagttcacg cagccgctcg cggcccgccg gctccagcgc gtcgtacagc
    14701 tcgtcggcga cccgggcgac cgagccgcgg atcccgccgg ccgcttcgta cccggcgaag
    14761 gtgagctggg tgccgcggcg ccgggcccag gtctgctgga gggcgtgggc gaggaacggc
    14821 agcgcgacgg agtcggcttc gccgccgggc gcttcccggc gcagctcgtg cagcagatgg
    14881 ccggcgagtc cgtcctccag gcgcaggccg gcgtgctcgg cgggccgttc gatcgcggcg
    14941 atcagttcct cgtcggacat ggcggggacg gtgaactgtc cggcccggag catgcgggcg
    15001 agccgcgcgt cgcgcatgca gagcccgtag aagtcggcgc gcagcccgag gacgatccgc
    15061 ggcccggtcg ccgctccggc gccggagacg gcccggacga acagctcccg ctcctccggg
    15121 tccacgcagt cggtgaagag ctcctccagc tggtcgatca ccaggacctc gggcccgccg
    15181 gttccgaagc gcccggcgcc cacctcccgt tcgacctctt cgaagggccg gtccaccgcc
    15241 cgcgcccagc gctcgaccag ggtacggaag ggccgcgcgc ccggcccctc gaccagcagc
    15301 accggtcccg tgccccgctc ctcgagtccg gcgacgagcc cggcccgcag gagcgaggac
    15361 ttccccgccc cggacgcgcc gacgagcacc accggcccgt cgccgtgcgt cacccggtcg
    15421 agcagctcgc gggccggctc ctcgcgcccg aagaagagat ggcgctgctc gggcaggaac
    15481 gggcgcatgc cggggtacgg gcaggggccg ccgcccgcgg gcacgtcggc ttcctccaag
    15541 ggtgccggag agcacacgtt ccgcgccacg acgagatccg tggcccggcc cacgccctcc
    15601 gcgtatgggc gggcggggcc gccctggaag cgccggtcga ggatccggta gacgtcgagc
    15661 agggtgagcc agcgcggccc gctcgggtcg ccctccgcca ggagccgcac cagctcgccg
    15721 ccgaagaggg tgtacggctg gtccacgggc gcgaaggagg cggcgtagcc ggacgccgag
    15781 gcgagcagga agctgccggg cggacgggcg gtcgcgtacg ggtcgcggtg ggcgtcgctc
    15841 ggggcggccg cggcccggcc ggagaagcag cagtcgagga cgacgaccgc gcgggcggac
    15901 gcgtcgccga gcagatggcg cacctcggcg tacggcacgg cggtgaccgt gtcgtcgggc
    15961 cgtgccgtgg ccgcagtggc cagatagagc tgcccgcccg ggccgagcag gccgtgcccg
    16021 gtgaagcaga acagcaccac gccgcccgcc gccgcctcga cggcgtcgcg gagcgcggcg
    16081 agcacttccg tcgggccggc cgggtcgatg agctcggtga cccggcccgc cgccatccca
    16141 caccgttcgc gcagcacccg ggccagctcc cgcgcggtgt gcgcggcgct cggcaggccg
    16201 gcgagccgca cgccgccgtc cgggccgccg cgctcacccg cgctctgctg tccggtgccg
    16261 acgacgacgg cgcggcagtc aggtccggcg agatcccccc atctctccgt cacggctcag
    16321 gggttctcgg gacccgaggg ctgccgcgcc ggctcctcca gggcccgcgc cacctccagc
    16381 gccagctctc cgctgctctc cggcgtgagg ccgcgcacgc cctgggaggt gacgacgacc
    16441 tgagtgccgt ccggcttggt gatcgtcacg gtctggctgc cgcgccgggt ctgcagccag
    16501 gccaccacgc cggccgccag cgtcacggtc aggccgccgg gctggagcag cagttcgatg
    16561 accgagccga acgcgcccat cgatccgggc gcaggcgatg cggggacgag cgggacgacg
    16621 gccggccgca gctcggggtc gccgcgcagc cactgccgca gctcgtaggc gtcttcggag
    16681 gtaccgccga cctccagggc aatgtgcacg tgcgttgacc tccgtagcgt tccgtcgagg
    16741 cggagccgta cgagggtacg ttcgtcactc ccttgtctcc aggtgggttt cggccgtcac
    16801 gtggttccgg gtacgccgaa ggccgtgcct ccgcgcaagg gctccggcgg ccagagggga
    16861 ggaggcctcc gacggccgga ttggcgacgt cgcctgcgcc tcacacgggc ggggaaccgg
    16921 cgtcggcggt cccgaggggg agcggggtgg cggcgaagac ggagtccggg tcgaccgcgg
    16981 acttcacggc cggcaggcgc cgggtgttcg gcccgtagga gtgcgcgacc tggtcgggag
    17041 tctccggccc caggaaattc ac
//
