LOCUS       reptomyces_RBGC_269821 16767 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_269821
VERSION     Streptomyces_RBGC_269821
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000372745.1
  ORGANISM  GCF_000372745.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1599
                     /protein_domains="PF00496"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491200"
                     /pseudo=False
                     /translation="MSRTTSPIPFGDRLPASRRVFLAAGGAGALALAAGCAAGGSADPG
                     PHPGAGNEGTPRRGGRLRAAFPGGGANENLDPHQANLFVEVARAKALFDKLADYGADLA
                     PVPRLAAGWEADQSLATWRVRLRRAAFHDGRPVTAEDVLYSFRRIADPKRAFRAKASLE
                     PIDLAASRALDPATVEFRLKRPYAEFANTLAAFGAYIVPKDADAFERPVGSGPFTFGSF
                     KPGSSLVLRRNDRYWEGAPHLDEVEFVVAAEESARTNALLGGQVEYAHELNPATARVHE
                     GKGRITVVRLRNSAMQGFVMKTDRPPFDDPRVRQAFFLIADRRQLVDGALSGAGEVGND
                     LFGKGYRYYAAGLPQRTRDLTRARALLREAGAEALRVTLDTAPAATGFVEAAGIFKEQA
                     AEAGVTIDVRIGNKDTYWKDILTGGTIASYRSGAMPIEAHVSQRLLTDSTTNASRWRVK
                     DFDDLYQQIQSTSDETLRTALYERMQRRLHAEGGFLIWGFADWIVATANRVRGVSVTAP
                     ANTLDWARFDRVWLA*"
     CDS             1597..2549
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491201"
                     /pseudo=False
                     /translation="VSPDRAWLGRRLLLGVGQTAALVVLIFALTEALPGDAAVALAGDQ
                     PDPQRIALIRENLGLDRSAGERLLDWVGGLAHGDLGTSLVSGRPVADLLADGLGPTLVL
                     AGVTATLLVPLSVGLGVLAARREGGPVDRTVSGLTAAVHAVPEFALGVLVITVFALRLG
                     WVPPTAIGTGGDLWAHPDVLVLPVLVLLSRPVCTISRLVRAGMIDAMASPYAAHARRLG
                     LTPTRVRWAHALPNALAPAGQQLARTCDWLLGGVIVVEALFVIPGLGTVLIDAVAARDI
                     PVVQGLAVVFGVVTVVVNLGADLVTRRLAPRAEVAA*"
     CDS             2547..3391
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491202"
                     /pseudo=False
                     /translation="VSERGKRGGPGSRRPVARRYALALGLIALPLLFAVFGPLFAGPAG
                     ARGVSFTGGQGHWLGTDFAGRDVWRQVLLGGRSVVLVAVAATGAAYLVAIPLGLAAALT
                     RRTWLAEVLIRPLDVLLAVPSLLFVLLVAALFRPGPAELVLVVALVIVPDAARVVVSAA
                     TEIAARPVVEALRMQGESWWRTAVGYVARSMRRTLAADCGIRLAGALYLVATAAFLGVG
                     VAPDASDWAVMVDRNRVGLFLQPWAVVVPAALIVALSMGTNLLFDAALQDPDERVGERL
                     *"
     CDS             3389..5109
                     /protein_domains="PF00005"
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491203"
                     /pseudo=False
                     /translation="VKDAEPVVAIADLRVEVAGRAIVDGVSLTARAGRITAVVGASGSG
                     KTTTGLALLGEFPPGARVTGSVRVTGAGPVAYIPQHPGAVLGPARRVGALLRDIARPAG
                     GGRAAIRERVYDALRAAAIPDPEEVVRRFPHQLSGGQQQRVVLAQALLLGARAVVADEP
                     TTGQDALTKQGVVERLAAVAGHGIAVLLLSHDVDVVRRLADDVVVLSHGRVVECGPAVR
                     ALTASEQPAGRTVAARRAALPAPRSRAVAESRLEVRDLVARHRGRGRSVDVLHGVSLAV
                     GAGECLALVGRSGSGKTTVGRCLAGLHSDHDGRILLDGVPLRRSLRARTRAELVGVQHV
                     FQDARAAFDEYRPVVEQVARTAVRLRGVEPGAARAQALRTLAELGLPAETSGRRPGALS
                     GGEVQRAALARALLARPRVLVCDEITSGLDASTRQGILDVLAELRERVELSLVFITHDL
                     AAAGRLADRIAVLDGGRVVEQGPARRILTEPGHPFTRMLVGAAGAGAGDGGEGIRLPGI
                     RSPAVEPSAVGPTHIDPPKIEHPAVDRPNSEAAFPEPPRADAPDADPSGSLRIGRE*"
     CDS             5228..5655
                     /protein_domains="PF01476"
                     /protein_domains="PF01476"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491204"
                     /pseudo=False
                     /translation="MEGTRHNDADARARSSARWPAVWVTVTNMSTKTMHFIHYTVQSGD
                     TLTVIANMFGTTIEQLVKWNKIANPDLINVGQKLIVNESDTPHDTFYTVKSGDTLTSIA
                     RRFGTTIEQLVKWNGIPNPDVINVAQRLIVAKSVPVQA*"
     CDS             complement(5731..6005)
                     /protein_domains="PF01471"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491205"
                     /pseudo=False
                     /translation="MPGDITQPCNFTVTRPTIKRGATGDAVKQEQCYLNHSLTGTKILE
                     DGIFGPVTEAATRRFQTCAKIGIDGICGPQTWSFLTFWANSPDFVC*"
     CDS             complement(6428..7638)
                     /protein_domains="PF00175"
                     /protein_domains="PF00970"
                     /protein_domains="PF00042"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491206"
                     /pseudo=False
                     /translation="VLSERSIPVIRATLPAVGAALDEITGRFYAGMFDAHPELLRDVFN
                     RGNQANGEQRQALAGSIAAFATMLVERPDARPDAMLARIANKHAALGITPDQYKIVHDH
                     LFAAIVDVLGDAITPPVAAAWEEVYWLMANALIAAEAALYRQAGFPDGRTWRRMEIVER
                     HEETPDAISLSLRPADGSPTPSFRPGQYVSVQIELPDGARQIRQYSLSCAPSRPLWRIT
                     VKRVLDGTAPDGEVSTWLHRHAAVGDQLTVSAPFGDLVLPDGDGPLLLASAGIGVTPML
                     AMLAHLATTASTRRVTVVHADRSRTDHPHRDEQRSLVAALPHATLQLWYEEADPDVLAG
                     GDGIASTGRVDIGSLALPDGLTAYLCGPMPFMRAVRGDLLRRGLPAAAIHYEVFGPDLW
                     LGQQ*"
     CDS             complement(7706..8148)
                     /protein_domains="PF02082"
                     /protein_domains="TIGR00738"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491207"
                     /pseudo=False
                     /translation="VQLTRFTDLALRAVMRLAVSGKGQALTTREVAEAVEVPYTHMAKA
                     VSRLRELGVVHARRGRGGGLELTVLGYRASVGWLVRELEGEGEVVVCEGESPCPLRGAC
                     RLRRALRQAQEAFYSSLDALTVADLVSQPTGPLLIQLGLRDQG*"
     CDS             complement(8234..9846)
                     /protein_domains="PF13556"
                     /protein_domains="PF17853"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491208"
                     /pseudo=False
                     /translation="MLDTGVPDLGQVLEVLGSSLLRPLTVPPEKPVPVSGVLIFERRAP
                     LPLPPIQDAILLAVGVGMAEAQAMELVGSAAEAGYACLVVKSFGEPVARLVEAAQQSGI
                     VLLAADEAVAWHHLDAMISSALTPTERFGQAAGAPAVGDLFALANAIAGMVGGATVIED
                     PQRRILAYSTLPGQAVDEGRRQGILGLQVPNGPEYDEQYRVLTRAGRTCRFPAFPGGLP
                     RLGIAVRVGSEVVGSIWVVNAGERLDSVAEQALSDVANNVALHLLAARTTESAVRRRYA
                     DLLRRLLADPSSVTAVAPQLGLDPNSPVAVAAFAVASVDAEDVLTAQAATRLADLVSLH
                     CEARYGRHGCALIDGTVYALLPSGPSPNAHRELVAYIARRAHSALRVPVRAGLGSLVQG
                     LRSIVSSRADADLVLRALSERQGDPEPCQVATIDEVWAGATLSALARMLATHEGLPRGL
                     GPAVRAHDLEHSTTYAPTILAYLDANGDVAAASHRLSVHPNTIRYRLSRATEIFGFDLA
                     DPDERLVLWLRLRLGDQLGW*"
     CDS             complement(9944..10095)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MVPGKTDSMSRVGSVSSAGAGDGGGGRDWLRFTGPWKVRSLDMPT
                     ARLLD"
     CDS             10144..11258
                     /protein_domains="PF00144"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491209"
                     /pseudo=False
                     /translation="MRYRTSAVVALACAASLITTPAKATATPQCDTTPIQTALKSLQSV
                     GVSGISVTVKSPSCGVWNGGVGLADLRTGRKVVGNEHSRIGSDTKTWTATVVLQLVGEG
                     KIDLDDTVDDYLPGLVHTKFYDGRSITIRQLLQHTSGLPDYLDAPFWENEDAHRWDHIE
                     PLQTVRQALTLPRPDRTESGFSYSNTNYNLVGLIVTKVTGRSIATEITERIIKRLGLCE
                     TQWPGDRTTIPKPDLRGYAERRGTLVDRTEWNTSEADASGALISDGADTTTFWTALLSG
                     KLLAPAQLAEMKKTVSEDVANERYGLGVERHEPVPGLVIWGHSGSMSSGHKFRNAVTDD
                     GRRAVTLLIGSETFDSDKVDSIMSKLMRDLR*"
     CDS             complement(11574..12751)
                     /protein_domains="PF00005"
                     /protein_domains="PF08352"
                     /protein_domains="TIGR01727"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491210"
                     /pseudo=False
                     /translation="VSMPAYGDGGRAGDFDSSETRGAATLTKDAAPGEVLLKVTGLRKH
                     FPIRKGLFQRRVGAVRAVDGIDFEVRSGETLGVVGESGCGKSTMGRLITRLLEPTAGTI
                     EFEGKDITHLGVGGMRPMRRDVQMIFQDPYSSLNPRHTTGTIIGAPFKLQGVEPEGGIK
                     KEVQRLLSVVGLSPEHYNRYPNEFSGGQRQRIGIARALALKPKLVVADEPVSALDVSIQ
                     AQVVNLMDDLQRELGLTYVIIAHDLSVVRHVSDRIAVMYLGKIVELADRDLLYKTPMHP
                     YTKALMSAVPIPDPRRRNARSERLLLDGDVPSPIAPPSGCRFHTRCWKATQICTTTEPP
                     LKELRPGQRLACHHPENFADQAPQDTILLSAAKRTTEPGTPGGRRTAGTAGG*"
     CDS             complement(12776..13887)
                     /protein_domains="PF00005"
                     /protein_domains="PF08352"
                     /protein_domains="TIGR01727"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491211"
                     /pseudo=False
                     /translation="MTEPGRSGAPVDGPAAASPSAASPAPSAFLDVRDLRVHFPTDDGL
                     VKSVDGLSFRLERGRTLGIVGESGSGKSVTSLGIMGLHTAGRYGRRKARVSGEIWLNGT
                     ELLSVGADHVRKLRGREMAMIFQDPLSALHPYYTIGEQIVEAYRIHHDVGKKAARKRAI
                     EMLDRVGIPQPDKRVDNYPHEFSGGMRQRAMIAMSLVNNPELLIADEPTTALDVTVQAQ
                     ILDLIRDLQEEFGSAVIVITHDLGVVAELADDILVMYGGRCIERGPAEQVFHEPRHPYT
                     WGLLGSMPRLDREQQDRLVPVKGSPPSLINLPSGCAFNPRCPYADVPKDDLSRTVRPEL
                     TEVGDRHWAACHMTQEQRERIWTEEIAPRL*"
     CDS             complement(13885..14882)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491212"
                     /pseudo=False
                     /translation="VLAYLIRRLFAAAVMLVVIIMVVFGIFFLVPKWAGVDIAASFVGK
                     QADPAAVEAVREKLGLSDPVHLQAWEFFKGIFAGRTFATGGDVVHCSAPCFGYSFKSEQ
                     AVWPVLTDRFPVTLGLALGAAVLWLVFGVAAGVLSALKRGSLWDRSAMVVALAGVSLPI
                     YFTGMLSLATFAFGLKWFDAQYVPLGQSLGGWFGGMILPWITLAFLYAAMYARITRATM
                     MEVLGEDYIRTARAKGLRERTVIGKHAMRSTMTPILTMLGMDLGALIGGAILTESTFNL
                     PGLGQAVLNAIRNQDLPIILGVVLITSLSVLLANLVVDVLYAVIDPRVRLT*"
     CDS             complement(14993..16767)
                     /protein_domains="PF00496"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1491213"
                     /pseudo=False
                     /translation="VTTQRTSGRRKQALAAAALVAGLLATAACGSSGGGKTSDAGYDAA
                     GNKVVNAGTTKGGTLKFAGTQDGDSWDTTRSYYGFAWNFMRYYSRQLVTYKTEPGKSGA
                     ALQPDLATDMGKVSDGGKTYTFTLRDGISWEDGKPITSKDVKYGIERQWAQDVLSGGPV
                     YLKDILDPNGEYQGPYQDESADKLGLKAVETPDDKTIVFHLPQVNSDFPQMLAMPSASP
                     VRQDKDTKSKYGLHPFSSGPYKFESYEPGKSLELVRNTQWKDTSDPVRKAYPDTVSVKF
                     FSNANDMDQRLIAGDYDLDLSQSGMSPQGRQTALKQHKGNLDNPLSGYVRYAVFPQNVK
                     PFDNEHCRKAVIHGADHLSLQTARGGPVAGGDIGTNMLPPTVPGTEGREYDPFALAGAD
                     KNGNIAKAKEELIACGKPDGFGTTIAVRNNKPVEVATAQSLQASLKKIGVDAQIDQYDG
                     SQTSGIVGSPSNVEKKGYGIIIDGWAADFPSVQGFGRPLWDSKYILESGNNNYALIKDE
                     AIDELFDAYAKELDEGSKGRIARQINHKVMEGAYYLPFTYEKYLNWRSSRLTNVYMTDA
                     YNGYDFISLGLKSSK*"
ORIGIN
        1 atgagccgca ccacctcacc cataccgttc ggcgaccgcc tgcccgcctc acgacgggtc
       61 ttcctcgccg ccggcggcgc cggcgcgctg gccctggcgg cgggttgcgc cgccggcgga
      121 tcggccgatc ccggtccgca ccccggagcg ggcaacgagg gcacgcccag gcgcggcggc
      181 cgactgcgcg cggcgttccc cggcggcgga gccaacgaga acctcgaccc gcaccaggcc
      241 aacctgttcg tcgaggtggc ccgggccaag gccctgttcg acaagctcgc cgactacggg
      301 gcggatctgg ccccggtgcc ccgcctggcc gccggttggg aggccgatca gagcctggcc
      361 acgtggcggg tccggctgcg ccgggccgcc ttccacgacg ggcggcccgt caccgccgag
      421 gacgtgctgt acagcttccg tcggatcgcc gatcccaagc gggcatttcg cgcgaaggcg
      481 tccctggagc cgatcgacct ggccgccagt cgggccctgg acccggccac ggtggagttc
      541 cggctcaagc gtccctacgc cgagttcgcc aacaccctgg ccgcgttcgg cgcctacatc
      601 gtgcccaagg acgccgacgc cttcgaacgt ccggtgggtt cgggcccgtt caccttcggc
      661 tcgttcaagc ccggcagttc gctcgtactc cggcgcaacg accggtactg ggagggcgcg
      721 ccgcacctgg acgaagtgga gttcgtggtc gcggccgagg agtcggcgcg caccaacgcg
      781 ctgctgggcg gacaggtcga gtacgcacac gagttgaacc cggccaccgc gcgcgtccac
      841 gagggcaagg gccgaatcac ggtggtgcgg ctgcgaaaca gcgcgatgca ggggttcgtg
      901 atgaagaccg accggccgcc gttcgacgac cccagggtgc ggcaggcgtt ctttctgatc
      961 gccgaccgcc gacaactcgt cgacggcgcg ctgtcgggcg ccggcgaagt gggcaacgac
     1021 ctgttcggca agggatatcg ctactacgcg gccggcctgc cccagcgcac ccgggatctc
     1081 acccgggccc gcgcgctgct gcgcgaggcg ggcgccgagg cactgcgggt caccctggac
     1141 accgcgcccg ccgccaccgg cttcgtcgag gcggccggga tcttcaagga acaggccgcc
     1201 gaggccgggg tcaccatcga cgtgcggatc ggcaacaagg acacctattg gaaggacatc
     1261 ctcaccggcg gcaccatcgc ctcctaccgc tcgggcgcga tgccgatcga agcgcacgtc
     1321 tcgcagcggt tgttgaccga ctccaccacc aacgcctcgc ggtggcgggt caaggacttc
     1381 gacgacctct accagcagat ccagtccacc tccgacgaga cgctgcgcac ggcactgtac
     1441 gagcgcatgc agcgccggct gcacgccgaa ggcggcttcc tgatctgggg gttcgcggac
     1501 tggatcgtgg ccaccgcgaa ccgggtgcgc ggggtgtcgg tgaccgcgcc cgccaacacc
     1561 ctggactggg cccgcttcga ccgggtctgg ctcgcgtgag cccggaccgg gcctggttgg
     1621 gtcggcggct gctgctgggc gtggggcaga cggcggcgct ggtcgtactg atcttcgcgc
     1681 tcaccgaggc gttgcccggc gacgcggcgg tggccctggc gggcgaccag cccgatccgc
     1741 agcggatcgc cctgatccgg gagaacctcg gcctggaccg gtcggccggc gaacgcctgc
     1801 tcgactgggt cggcgggttg gcgcacggcg atctgggcac ctcgctggtc tccggccgac
     1861 ccgtcgccga tctgctcgcc gacgggctgg gccccacgct ggtgctggcc ggggtcaccg
     1921 cgaccctgct cgtgccgctg tcggtggggc tgggggtgct cgccgcgcgc cgcgagggcg
     1981 ggccggtgga ccggacggtc agcgggttga cggcggcggt gcacgccgtc ccggagttcg
     2041 ccctgggggt gctcgtgatc acggtgttcg cgctgcgcct ggggtgggtg ccgcccaccg
     2101 ccatcggcac cggcggcgac ctgtgggcgc accccgatgt cctggtcctg ccggtgctgg
     2161 tgctgctgtc ccggcccgtg tgcacgatca gccgtctggt gcgcgcgggg atgatcgacg
     2221 ccatggcgtc gccgtacgcg gcgcacgccc ggcggctggg gctgaccccg acccgggtgc
     2281 gctgggccca cgccctgccc aacgccctgg ccccggccgg tcagcaactg gcccgcacct
     2341 gcgactggtt gctcggcggc gtgatcgtgg tcgaggctct gttcgtgatc ccgggcctgg
     2401 gcacggtgtt gatcgacgcg gtcgccgcgc gtgacatccc ggtggtgcag ggcctggcgg
     2461 tggtgttcgg ggtggtgacc gtagtggtca acctcggcgc cgacctggtc acccgacgcc
     2521 tggcgccgcg cgcggaggtg gcggcgtgag cgaacgcgga aaacggggcg gacccggctc
     2581 gcgccggcca gtggcgcggc ggtacgcgct cgccctcggg ctgatcgccc tgccgctgct
     2641 gttcgcggtg ttcgggccgc tgttcgcggg cccggccgga gcgcgcggcg tgtcgttcac
     2701 cggtggccaa gggcactggc tgggcaccga cttcgccgga cgtgacgtct ggcgccaggt
     2761 gctcctcggc ggtcgatcgg tggtgctcgt ggcggtcgcc gcgacggggg ccgcctacct
     2821 ggtggcgatc ccgctcgggc tggccgccgc gctgacccgg cggacctggc tcgcggaagt
     2881 gctgatccgg ccgctcgacg tgctgctcgc ggtgccctcg ctgctgttcg tgctcctggt
     2941 ggccgcgctg tttcggccgg ggccggccga actggtcctg gtggtggctc tggtgatcgt
     3001 gcccgacgcc gcccgagtgg tggtgtcggc ggccaccgag atcgcggcgc ggccggtggt
     3061 ggaggcgctg cggatgcagg gcgaatcgtg gtggcggacg gccgtcggct acgtggcgcg
     3121 gtcgatgcga cgaaccctcg ccgccgattg cggcatccgg ctggccggcg cgctgtacct
     3181 ggtggccacc gccgcgttcc tgggcgtggg ggtggccccc gacgcctcgg actgggcggt
     3241 gatggtggac cgcaaccggg tcggcctgtt cctccagccg tgggcggtgg tggtccccgc
     3301 ggcgctgatc gtggcgctgt cgatgggcac gaatctgctc ttcgacgcgg cgctgcaaga
     3361 ccccgacgag cgggtgggag aacgactgtg aaggatgcgg aaccggtcgt ggcgatcgcc
     3421 gacctgcggg tggaggtcgc cggacgggcg atcgtggacg gcgtgagcct gaccgcgcgg
     3481 gcggggcgga tcaccgccgt cgtgggcgcg tccggcagcg gcaagaccac cacgggcctg
     3541 gcgctgctcg gcgaattccc gcccggcgcc cgggtgacgg gcagcgtacg ggtcacgggc
     3601 gccggaccgg tggcctacat cccacaacac cccggcgccg tgctcggccc ggcccgtcgc
     3661 gtcggcgcgc tgctgcgcga catcgcccgg ccggcgggtg gcgggcgcgc cgcgatccgg
     3721 gaacgggtgt acgacgcgct gcgggcggca gcgatcccgg atccggagga ggtggtccgg
     3781 cgcttcccgc atcagctctc cggcgggcag cagcagcgtg tggtgttggc ccaggccctc
     3841 ctgctcgggg cacgcgccgt ggtcgccgac gagcccacca cggggcagga cgcactcacc
     3901 aaacaggggg tcgtcgagcg tctggcggcg gtggccgggc acgggatcgc cgtgctgctg
     3961 ctcagccacg acgtggacgt ggtgcgccga ctggccgacg atgtggtggt gctttcccac
     4021 gggcgagtgg tcgaatgcgg cccggccgta agggcgttga cggcatcgga gcagcctgcc
     4081 gggcggaccg tcgccgcgcg gcgggcggct ttgcccgccc cccgctcccg cgcggtggcc
     4141 gagtcccgat tggaggtccg cgacctggtg gcccgacatc gtgggcgcgg gcggtcggtc
     4201 gacgtgctgc acggggtgag tctggcggtg ggggcgggcg aatgcctggc gctggtgggg
     4261 cgttccggca gcggtaaaac caccgtgggc cggtgcctgg ccggactgca cagcgaccac
     4321 gacggccgga tcctgctcga cggcgtgccg ttgcggcgct cgctgcgcgc tcgcactcgc
     4381 gccgaactgg tcggcgtgca gcatgtgttc caggacgcgc gggccgcatt cgacgagtat
     4441 cgcccggtgg tcgagcaggt ggctcggacg gcggtccggc tgcgcggcgt cgagccgggc
     4501 gcggcccgtg cgcaggcgct gcgcacgctg gccgaactcg gcctgccggc cgagacgtcc
     4561 ggccgccgcc cgggcgcgtt gtccggaggt gaggtacagc gcgccgcgtt ggcccgggcc
     4621 ctgctcgccc gacctcgggt gctggtgtgt gacgagatca cctccggcct ggacgcgtcg
     4681 acccgacagg ggatcctgga tgttcttgcg gaattgcgcg aacgcgtcga gctgagcctg
     4741 gtgttcatca cgcacgattt ggcggcggcg ggtcggctcg ccgatcggat cgcggtcctg
     4801 gacggcgggc gggtggtcga acagggcccg gcccggcgca tcctgaccga gcctgggcac
     4861 ccgttcacca ggatgctggt gggcgccgcg ggtgctggtg cgggggatgg gggtgagggg
     4921 atcaggttgc ctggcatccg gtcacccgcc gtcgagccgt ccgccgtcgg gccgacgcac
     4981 atcgaccctc cgaagatcga acatccggct gtcgatcgtc cgaacagcga ggcggctttt
     5041 cccgaaccac cccgcgccga cgcgcccgac gcggatccgt ccggatccct gcgcatcggc
     5101 cgggagtgac cgacggagga ctgcggcgaa ccctccgggg gagttgggtc cggcagggcg
     5161 aggtcgggcc gccgaagaca ggtggttacg ccggttgctc gccgaacggg cctggaagtt
     5221 gctccaatgg agggcacacg acacaacgat gccgacgcgc gggcgcgttc ctccgcgcga
     5281 tggccggctg tctgggttac cgtgaccaat atgtcgacaa aaacaatgca tttcatccat
     5341 tacacggtcc agtccggcga cacgctcacg gttatcgcga acatgttcgg gacgacgatc
     5401 gaacaactcg tcaagtggaa caagattgcc aacccggacc tgatcaacgt cggtcagaaa
     5461 ctcatcgtca acgagtccga cacaccgcac gacaccttct acacggtgaa gtccggtgac
     5521 acgctcacgt ccatcgcccg caggttcggc acgacgatcg agcaactggt caagtggaac
     5581 ggaattccca acccggacgt gatcaacgtc gcgcagcggc tgatcgtcgc caagtcggta
     5641 ccggtacagg cctgacaaca acaggggtga acggcggttg gcatgccaac cgccgttcac
     5701 cccaagccgt tcgacccgga tgcgggggtt cagcagacga agtccggcga gttggcccag
     5761 aacgtaagga acgaccaggt ctgcgggccg cagatgccgt cgatgccgat cttcgcgcac
     5821 gtttggaacc tgcgcgtggc ggcctcggtc accggcccga agattccgtc ctcgaggatc
     5881 ttggtcccgg tcaacgagtg gttgaggtaa cactgctcct gtttgaccgc gtcccccgtg
     5941 gcaccgcgct tgatcgtggg cctggtgacg gtgaagttgc agggctgagt gatgtcgccg
     6001 ggcatgttcg gctccttggc gtggcgcggt ttgtcagtcg ctcggcgcga cgatgggcgt
     6061 cgcgcgttcg gctcgattgc catcgctcgc gcccatccca gcggaacaca aggcggtacg
     6121 aaccgcatgt caacgcgcgc cgcgaggagt gacccgcgag ggagtgatcc ggcgattcgg
     6181 cgagcgtctc gggcggcgca ccgattgccg acgcacgcat ccgtattccg tatactccgc
     6241 caatcgtggt acgaacccgg ccggcctcgt cgacggccca catgtccgcc gggtctgttc
     6301 gaccgttcga ccgactccct ccaacccggc acaccgtttc gaggcggccg cccgggcctg
     6361 tggaccgacc ccgacggcaa cgcctcgatc acgtgggagt acgactggcc gacccgcgag
     6421 actcgcctac tgttgcccca gccacaagtc gggaccgaag acctcgtagt ggatcgccgc
     6481 agcgggcaaa ccgcggcgca acagatcgcc gcgaacggcg cgcatgaagg gcatcggtcc
     6541 gcacagatag gcggtcaggc cgtccggaag tgccagggag ccgatgtcga ctcggccggt
     6601 ggatgcgatg ccatcgccgc cggcgaggac gtcggggtcc gcctcttcgt accaaagttg
     6661 cagggtggca tgcggcaacg ccgcgaccag cgaccgttgt tcgtcgcgat gggggtgatc
     6721 ggtacgactg cggtcggcgt ggacgacggt cacccggcgg gtcgaggcgg tggtcgccag
     6781 gtgggccagc atggcgagca tgggtgtgac gccgatgccg gcggacgcca gcagcagcgg
     6841 gccgtccccg tcgggcagaa ccaggtcgcc gaacggtgcg gacacggtca gttggtcgcc
     6901 cactgcggcg tgtcggtgaa gccatgtcga gacttcgccg tccggagccg tgccgtcgag
     6961 gacgcgtttg acggtgatcc gccagagcgg tcggctcggc gcgcaggaca gactgtactg
     7021 gcggatctgg cgtgcgccgt ccggaagttc gatctgcaca ctgacgtact gcccgggtcg
     7081 gaacgacggc gtgggactgc cgtcggccgg tcgcaggctc agcgagatcg cgtcgggggt
     7141 ctcctcgtgt cgttcgacga tctccatccg tcgccaggtc cgcccgtcgg ggaacccggc
     7201 ctgccggtag agcgcggcct cggcggcgat cagggcgttg gccatcagcc aatagacctc
     7261 ctcccaggcg gcggcgaccg ggggagtgat cgcgtcgccg agcacgtcga cgatcgccgc
     7321 gaagaggtga tcgtgaacaa ttttgtattg atccggtgtg atgcccagag cggcgtgctt
     7381 gttggcgatc cgggcgagca tcgcgtccgg tcgggcgtcc ggccgttcca cgagcatggt
     7441 cgcgaacgcg gcgatggatc cggccagtgc ctgtcgctgc tctccgttcg cctggttgcc
     7501 tcggttgaac acgtcgcgca gcaactcggg gtgggcatcg aacatgccgg cgtagaaccg
     7561 cccggtgatc tcatcgaggg cagcgccgac ggccggcagc gtggcacgga tgaccggtat
     7621 ggatcgctcg gacaacacgg atcctccaaa ttggtagatg atcttcatat ttaagcgcgg
     7681 acgtcgaccc cgccggggga gaggtcagcc ctggtcgcgc aggccgagtt gtatcaacaa
     7741 cggaccggtc ggctgtgaca ccaggtcggc cacggtcagc gcgtcgagcg aggagtagaa
     7801 ggcttcctgc gcctggcgca gcgcgcgtcg caatcggcac gcgccgcgca acgggcatgg
     7861 cgactcgccc tcgcacacga cgacctcacc ctccccttcg agctcacgca ccagccagcc
     7921 caccgaagcc cggtatccga gaacggtcaa ctccaagccg ccgccgcggc cgcgccgggc
     7981 atgcacgacg ccgagttccc gaagccggga gaccgccttg gccatgtgcg tatacggcac
     8041 ctcgaccgcc tcggcgactt cgcgcgtggt cagcgcctgg cccttgccgg agaccgccag
     8101 gcgcatgacg gcgcgtagcg ccagatcggt gaatcgcgtc aactgcacgg aggcgacggt
     8161 atcaaatacg catctgcgat gcgtattcag gtcccctcac atgaatcgag ccccgtttgc
     8221 cggcgccggg gcctaccagc cgagttggtc gccgagccgc aaccgcagcc acagcaccag
     8281 acgctcgtcc gggtcggcga gatcgaaccc gaagatttcc gtggcgcggg agagccggta
     8341 ccggatcgtg ttcgggtgca cggacagccg atgggaggcg gcagcgacat cgccgttggc
     8401 gtccaggtag gcgaggatgg tgggcgcgta ggtggtgctg tgctcgagat cgtgggcacg
     8461 gaccgccggc ccgagcccgc gggggagccc ctcgtgcgtg gccagcatcc gggccagtgc
     8521 ggacagcgtc gcgccggccc acacctcgtc gatcgtggcc acctggcacg gctccggatc
     8581 accctgccgt tcggagagcg cacgcagaac gaggtccgcg tcggcgcgtg agctcacgat
     8641 cgagcgcagc ccctggacga gcgagccgag tccggcccgg acgggcacac ggagcgcgct
     8701 gtgggcccgc cgcgcgatat aggcgacgag ttcacggtgc gcgttcggcg aaggcccgct
     8761 cggcagcagc gcgtagaccg ttccgtcgat caacgcgcaa ccgtgccggc cgtagcgcgc
     8821 ctcgcagtgc aagctcacca agtcggcgag ccgggtggcc gcttgtgccg tgagaacatc
     8881 ctcggcatcg accgaggcga cggcgaatgc ggccaccgcg acgggcgagt tcgggtccag
     8941 gccgagctgt ggggccactg cggtgacact gctcgggtcg gcgagcaacc gccgcaacag
     9001 gtcggcgtac ctgcgccgga cggcagattc cgtggtacga gctgcgagca ggtgcagcgc
     9061 gacgttgttc gccacatcgg aaagggcctg ttcggcaacg gagtccaggc gttccccggc
     9121 attgacgacc cagatcgaac ccaccacctc gctgcccacg cggaccgcga tgccgaggcg
     9181 aggaagaccc ccgggaaagg cagggaaccg gcaggtgcgc cccgcccggg tgagcacccg
     9241 gtattgctcg tcgtattccg ggccgtttgg cacctggagg ccgaggatgc cctggcggcg
     9301 gccctcgtcg acggcctggc cgggcaaagt cgagtacgcg aggatgcgcc gctggggatc
     9361 ctcgatcacg gtggctccgc ccaccatccc cgcgatcgcg ttggccaacg cgaacagatc
     9421 gccgacggcc ggggcacccg cggcctgccc gaaacgctcc gtcggagtaa gggccgagga
     9481 gatcatggca tccaaatggt gccaggccac ggcctcgtcg gcggcaagca gcacgatgcc
     9541 ggactgctgg gcggcttcca ccagccgggc gaccggctcg ccgaaactct tcacgaccag
     9601 gcaggcgtac ccggcctcgg ccgccgaacc gaccagctcc atcgcctgcg cttcggccat
     9661 ccccactccg acggcgagca ggatcgcgtc ttggatgggg ggaagcggaa gcggggctcg
     9721 ccgctcgaag atgagtacgc ccgagaccgg caccggtttc tccggcggta cggtcaacgg
     9781 ccgcagcagc gacgagccca gcacttccag gacttgtccg agatcgggaa ccccggtatc
     9841 gagcatcctc acctctttgg ccagacacac aaagcattcg aagaatctct ggacgagtac
     9901 cgcatgtatc cggccagtcc aggcgccacg ctgtccgcat gctcaatcca gcaagcgtgc
     9961 ggtgggcatg tccagtgacc gtaccttcca cggccccgtg aagcgcaacc aatcgcggcc
    10021 acccccgccg tcccccgcac cggcgctcga gaccgaaccg actcgggaca tcgagtccgt
    10081 cttccccggc accaggcgta atcgatcgca ccacacgcat cagaactgca aaaggagatt
    10141 tcatgcgata ccggacaagt gctgtcgtgg ccttggcgtg cgcagcctct ctgataacga
    10201 cgcccgcgaa ggcaaccgcg acaccgcagt gtgacaccac gcccatccag acagctctga
    10261 agtcgctgca aagtgtcggc gtctcgggga tcagcgtgac ggtgaagagc ccgagctgcg
    10321 gcgtctggaa cggcggtgtc ggactcgccg atctcagaac gggccgtaag gtcgtcggca
    10381 atgagcacag ccggatcggc agcgacacca agacctggac ggccacggtc gtgcttcagc
    10441 tcgtcggcga gggcaaaatc gatctcgacg acaccgtgga cgactatctg cccggtctcg
    10501 tccacaccaa attctatgac ggacgcagca tcacgatccg gcagcttctg cagcacacca
    10561 gcggcttgcc cgattacctg gacgcgccgt tctgggagaa cgaggacgcg caccgctggg
    10621 atcacatcga gcccttgcag acggtccgac aggcgctcac gctacccagg cccgaccgga
    10681 cggagtccgg tttttcctac tccaacacca actacaacct ggtcggtctg atcgtcacga
    10741 aggtcacggg tcgcagcatc gccaccgaga tcacggagcg gatcatcaag cgtctcggac
    10801 tgtgcgagac ccaatggccc ggcgatcgga ccacgatccc caagccggac ctgcgaggct
    10861 acgcggagcg gcggggcact ctggtggaca ggacggaatg gaacacctcg gaggccgacg
    10921 cgtcgggcgc tctgatctcc gacggtgcgg acaccaccac cttctggacc gccctgttgt
    10981 ccgggaaact gctggctccg gcccaactcg ccgagatgaa gaagaccgtt tcggaggacg
    11041 tcgcgaatga gcgctacggc ctgggagtcg agcgccacga gcctgttccg ggccttgtca
    11101 tctggggaca cagcggcagc atgtccagcg gccacaagtt caggaacgcc gtcaccgacg
    11161 acggccgacg ggccgtgacc ctgctgatcg gctcggaaac gttcgactcg gacaaggtgg
    11221 actccatcat gagcaaactc atgcgcgacc tccgctgacg gtatcgcctg aactccccgg
    11281 cccggcaggg tgctaccgaa agcgtcgcag atctccgcac cggatccgcc cctgtggacg
    11341 acagagcgat gacgccgcca caggggcaag tccggtccgg ccggcgccag ttgccgccga
    11401 ttgagtgagg ttcccgcgtc cgtcgggtgg acggccgccg gtccacatcc gccttcgcac
    11461 gcgaaaggct ccgttgtgtc gttgagggca tcaccgcgca gtcgtcgccg atgccctcga
    11521 cgaccttttc atggccattc cggttcctgt gccatcgggt acttcgcggc cgtcaccccc
    11581 cggccgtacc cgcggtacgg cgcccaccgg gtgtgcccgg ctccgtggtc cgcttcgcgg
    11641 ccgacagcag gatggtgtcc tgtggggcct ggtcggcgaa gttctccggg tggtggcagg
    11701 ccagccgctg accgggcctc aactccttga gaggcggctc ggtcgtcgta cagatctgcg
    11761 tcgccttcca gcaccgggtg tgaaagcggc agccgctggg cggggcgatc ggcgagggca
    11821 cgtcgccatc gagcaggagg cgctcgctcc tggcgtttct gcgccgcggg tcggggatcg
    11881 ggacggccga catgagcgcc ttggtgtacg ggtgcatcgg tgtcttgtag agcaagtccc
    11941 ggtcggcgag ttcgacgatc ttgccgaggt acatcaccgc gatccgatcc gagacgtgcc
    12001 ggacgacgga caggtcgtgc gcgatgatca cgtaggtcag gcccagttcc cgctgaaggt
    12061 cgtccatgag gttgacgacc tgggcctgga tcgacacgtc cagcgcggac accggctcgt
    12121 ccgccaccac cagcttcggc ttgagggcga gcgcgcgggc gatgccgatg cgctggcgct
    12181 ggccgccgga gaactcgttc ggatagcggt tgtagtgctc ggggctgagg ccgaccaccg
    12241 acagcagtcg ctgcacttcc ttcttgatgc cgccctcggg ttccacgccc tggagcttga
    12301 agggggcgcc gatgatcgtg ccggtggtgt ggcgcgggtt cagcgacgag tacgggtcct
    12361 ggaagatcat ctgcacgtcg cggcgcatcg ggcgcatgcc gcccactccg aggtgggtga
    12421 tgtccttgcc ctcgaactcg atcgtccccg cggtcggttc gagcagccgg gtgatcagcc
    12481 ggcccatcgt cgatttgccg cagcccgact cgcccacgac acccagggtc tcgcccgagc
    12541 gcacctcgaa gtcgatgccg tcgacggcgc gcaccgcgcc gacccggcgt tggaagaggc
    12601 ccttccggat cgggaagtgc ttccgcagcc cggtcacctt cagcaggacc tcaccgggcg
    12661 cggcgtcctt ggtcagggtg gccgcaccgc gggtctcgga cgagtcgaaa tcaccggccc
    12721 gcccaccgtc gccatatgcg ggcatgctca ctgcgttgtc ctccgcgttc tcactcacag
    12781 cctcggcgca atctcttcgg tccagatccg ctcccgctgc tcctgcgtca tgtggcaggc
    12841 ggcccagtgc ctatcgccga cctcggtcag ctcggggcgg accgtgcggc tgaggtcgtc
    12901 cttcggcacg tccgcgtacg ggcagcgcgg gttgaaggcg cagccggacg ggaggttgat
    12961 cagggagggt ggggagccct tgaccgggac gagccggtcc tgctgctcgc ggtcgaggcg
    13021 cggcatcgag ccgagcagac cccaggtgta ggggtgccgg ggctcgtgga acacctgctc
    13081 cgccgggccg cgctcgatgc agcgaccgcc gtacatcacc aggatgtcgt cggcgagttc
    13141 ggcgacgacg cccaggtcgt gggtgatgac gatgaccgcg gagccgaact cctcctgcag
    13201 atcccggatg aggtccagga tctgcgcctg gacggtgacg tccagggcgg tggtgggctc
    13261 gtccgcgatg agcagttcgg ggttgttgac cagggacatc gcgatcatcg cgcgctggcg
    13321 catgccgccg gagaactcgt gcgggtagtt gtccacccgt ttgtccggct gcgggatgcc
    13381 cacccggtcg agcatctcga tcgcacgctt gcgggcggcc ttcttgccga cgtcgtggtg
    13441 gatccggtac gcctcgacga tctgctcgcc gatcgtgtag tacgggtgca gcgcggacag
    13501 tggatcctgg aagatcatcg ccatctcacg gccccgcagc ttgcgtacgt ggtcggcgcc
    13561 gaccgacaac aactcggtgc cgttcagcca gatttcgccg gagacccgcg ccttgcgcct
    13621 gccgtatcgg ccggcggtgt gcaggcccat gatgccgagc gaggtcaccg acttgccgga
    13681 gcccgactcg ccgacgatgc cgagggtcct gcccctctcc aaccggaagc tgagcccgtc
    13741 gacggacttg accagaccgt cgtcggtagg gaagtgcacc ctcaggtcac gcacgtccag
    13801 gaaggcactc ggagcgggcg aagcggcgga gggcgacgcg gccgcgggcc cgtccaccgg
    13861 ggctccgctc ctgccgggtt cggtcatgtg agcctcactc gggggtcgat cacggcgtac
    13921 aggacatcga ccacgaggtt ggccaacaac accgagaggg aggtgatcag gacgacgccc
    13981 aaaatgatgg gcagatcctg gttcctgatg gcgttcagca cggcctggcc gaggccgggc
    14041 aggttgaacg tcgactcggt gaggatcgcg ccaccgatga gggcgccgag gtccatgccc
    14101 agcatggtga ggatcggcgt catcgtggag cgcatggcgt gctttccgat gacggttcgc
    14161 tcccgcaggc ccttggcgcg tgcggtacgg atgtagtcct cgcccaggac ctccatcatc
    14221 gtggcgcggg tgatgcgcgc gtacatcgcc gcatagagga aggcgagggt gatccacggc
    14281 aggatcatgc cgccgaacca gccgcccagg ctctggccga gtggcacgta ctgcgcgtcg
    14341 aaccatttca gcccgaacgc gaacgtcgcc agggagagca tgccggtgaa gtagatgggg
    14401 agggacacac ccgcgagggc gacgaccatc gcgctgcggt cccagaggct gccgcgcttg
    14461 agcgcggaga gcacacccgc cgcgacaccg aagaccagcc acagcacggc ggcaccgagg
    14521 gcgagcccca gggtcaccgg gaaacggtcg gtcagcaccg gccagacggc ctgttcgctc
    14581 ttgaacgagt agccgaagca cggtgcggag cagtgcacga cgtcgccgcc ggtcgcgaag
    14641 gtgcggcccg cgaagatgcc cttgaagaac tcccatgcct ggaggtggac ggggtcgctc
    14701 aggccgagct tctcccgcac ggcctcgacg gcggcggggt cggcctgttt gcccacgaag
    14761 ctcgcggcga tgtcgacgcc cgcccatttg gggacgagga agaagatgcc gaagaccacc
    14821 atgatgatga ccaccagcat cactgcggcg gcgaacagcc gcctgataag gtaagcgagc
    14881 acagcctacg gcctgccgcg gatcgcaggc cgccggggct tccggcggcc cgggatcacg
    14941 ccgcgccggc cttcacctgc ctttcgtgcc gttcggcggg tgtgccggag ttcacttcga
    15001 ggacttgaga ccgaggctga tgaagtcgta gccgttgtac gcgtcggtca tgtagacgtt
    15061 ggtgagtcgg ctggagcgcc agttcaggta cttctcgtag gtgaagggca ggtagtacgc
    15121 gccctccatg accttgtgat tgatctgcct ggcgatccgg cccttgctgc cctcatcgag
    15181 ttccttggcg taggcgtcga agagttcgtc gatcgcctcg tccttgatca gggcgtagtt
    15241 gttgttgccg ctctccagga tgtatttgct gtcccacagc ggccgaccga agccctggac
    15301 ggacgggaag tccgcggccc agccgtcgat gatgatgccg tagcccttct tctccacgtt
    15361 ggaggggctg ccgacgatgc cggaggtctg cgagccgtcg tactggtcga tctgcgcgtc
    15421 gacgccgatc ttcttcaacg acgcctgcag ggactgggcg gtggccacct cgaccggctt
    15481 gttgttgcgg acggcgatgg tggtaccgaa gccgtccggc ttgccgcagg cgatcagttc
    15541 ctccttggct ttggcgatgt ttccgttctt gtcggcgccg gccaaggcga acgggtcgta
    15601 ctcccggccc tcggtacccg ggaccgtcgg cggcagcatg ttggtcccga tgtcaccgcc
    15661 ggcgacgggg ccaccgcgcg cggtctgcag ggacaggtgg tcggccccgt ggatgaccgc
    15721 cttgcggcag tgctcgttgt cgaacggctt cacgttctgc gggaagaccg cgtaacggac
    15781 gtaaccggag agcggattgt ccaggttgcc cttgtgctgc ttcaacgcgg tctggcgacc
    15841 ctgcggcgac atgccgcttt ggctgaggtc caggtcgtag tcgccggcga tcagtcgctg
    15901 gtccatgtca ttggcgttgg agaagaattt gacgctgacg gtgtccgggt aggccttgcg
    15961 aaccgggtcc gaggtgtcct tccactgcgt gttgcggacc agttccaggc tcttgcccgg
    16021 ctcgtacgac tcgaacttgt agggaccact ggaaaacgga tgcaggccgt acttggactt
    16081 ggtgtccttg tcctggcgta ccggggaggc cgacggcatc gcgagcatct gtgggaagtc
    16141 gctgttgacc tgcggcaggt ggaagacgat cgtcttgtcg tcgggtgtct cgaccgcttt
    16201 caggcccagc ttgtcggcgg actcgtcctg ataggggccc tggtactcgc cgttggggtc
    16261 gaggatgtcc ttgaggtaga ccggaccacc cgacagcacg tcctgcgccc actggcgctc
    16321 gatgccgtac ttgacgtcct tggaagtgat cggcttgccg tcctcccagc tgatcccgtc
    16381 gcgcagggtg aacgtatacg tcttgccgcc gtccgagacc ttgcccatgt cggtggcgag
    16441 gtcgggctgt agcgcggcgc ccgacttgcc cggctcggtc ttgtaggtga ccagttggcg
    16501 gctgtagtac cgcatgaagt tccaggcgaa gccgtagtag ctccgcgtgg tgtcccacga
    16561 gtcaccgtcc tgggtgccgg cgaacttcag ggtgccgccc ttcgtggtgc cggcgttcac
    16621 gaccttgttg ccggcggcgt cgtagccggc gtcgctcgtt ttgccgccgc cactgctgcc
    16681 gcacgccgcc gtggccagca gccctgcgac caaggccgca gcggccagtg cctgcttacg
    16741 ccgccctgag gtgcgttggg tagtcac
//
