LOCUS       treptomyces_RBGC_27503 17333 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_27503
VERSION     Streptomyces_RBGC_27503
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000958545.1
  ORGANISM  GCF_000958545.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..780)
                     /protein_domains="PF13561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4948366"
                     /pseudo=False
                     /translation="MRGLSGQSAIVTGGAQGIGRAVVDRLVEEGAHVLIADVNEEYGKA
                     AAEEINSRVGSPVTRFVRTDVSDEESVERAVAAAVESFGSVRFLINCAAAFIMRGVEAT
                     VDEWRRVMDVNIMGQALCVKHSAPFMKAAGGGSIVNIASISGHIAQAGLMTYSTTKGAV
                     VNMTRCMALELASDNIRVNAVNPGTVWNENNERFHREVLGMTREQADRAPEIGGRHLLG
                     RTADPEEIAASVVFLLSAEASYITGTNLMVDAGYTAM*"
     CDS             complement(1338..2929)
                     /protein_domains="PF00501"
                     /protein_domains="PF13193"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4948367"
                     /pseudo=False
                     /translation="MSDRTILPGILNTGREEFLHEFLLRMAGTLPDRPAVIEPVGSERY
                     AVTTYRELELLVRDHMAALDGLGLEIGDRVILEADLSAASIAALLACSALGLTFVPVGK
                     RPPEQRLASIMRTTEPAFYLRCRGSGDADVPFGVGLGHLEGSSLTIERAPVDRARRRRE
                     PTVTDPAYVIFTSGTTGRPKGVVMSHRAVTSFYHGMADQRLVTPDDRVANTSPLQFDFS
                     LINLGLALGSGAALVAVPPESLRWPRRFVRVLKETGATQVNGVPSIWRPVLRHEQRGLA
                     DLDRLRGILFCGEDFPLPELRHLRELLPRVRVTNCYGSTESMACSFEEVPNPLPADAKR
                     LSIGFAHKGAEMLLVDEAGRLIERPGLVGEIVLRSPALFTGYWDDPDATEAALLPDPVS
                     PRSSQVVLRTGDLGHMGQGGEMYFCGRADSQVQIRGNRVELDEVRHRLLEFPGVMAAEV
                     LVLGPAGGDRRLGAFVVASARSTDVGPAELRAHCAQALPSYMIPSELHVLDALPTTSNG
                     KTDRESLVALVSG*"
     CDS             3278..5331
                     /protein_domains="PF03704"
                     /protein_domains="PF13191"
                     /protein_domains="PF00486"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4948368"
                     /pseudo=False
                     /translation="LREPENDQLEFSLLGPLEVRSGGTPLDAGPPKRRVLLIRLLVEGG
                     RTVSTDRLRKDLWGWHDSPGTVSSLHAHISRLRALLEPSRAHRRQGSVLVTEPTGYALR
                     VRPRTLDTVRFQEGADDAQQLMEAGDIDAAYDRAEEALGRWRGTPYAEAADYRFAEREI
                     LHLEETRLRVSQVRTSALLSLRRFDRALSGARELTTAHPMDETAWVLMMRALYLSGRPA
                     EALDGYQTIRARLNEEGLEPGPALRATQLAILRHDIDRIAPAPRQQVVLSAPAPRETAA
                     GCRPRLPCRSAELSQLARVLDVARSGRAAWALVSGELGVGKTGLVEELAAHADALGMRT
                     VWTRGSAESDAGQEADPFRTAAEMLRQLLPERPLSPDSLPPSTTGGPGGHTLGHFRAFD
                     RIARDLLHALADRPTLCVIDDMQHVDADSRTLLTFLAVHLRTAPLAVICVSRDFGQAGL
                     DGFSLTVMREGGCHLRLVPFTAQESREVVRRWCASSPTSRVAAADDIDLMARALHWRSA
                     GNPLWLTELLRAAVNNGDWAGERIPRVAHHILMSIARGLRQSLRSFLETAAVIGEPVDI
                     LLSASVLGCSAEAVLDLIEEALTAGLLVWRDGQDYGEAGYRFTWPLFKEVVLAEMSPLQ
                     KQRLRTASAARRLADPPGGRARAPKRRAPRSAPEATVRLTPAPAMGEQR*"
     CDS             5329..6509
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4948369"
                     /pseudo=False
                     /translation="MSVHDQVVDLARGAEPVALEWFGTSLRVHVPVPETLQYVADHHRV
                     GPPTVKAPPYRSAALFAVAAPNILDELRDQAARRTVSRRESFKGVWYAYWETADGATMV
                     VDETHAYQHALLTRDFTSWAVVGERPEDLGLVVARTIRELVREDLLAMGAVTFHASAAE
                     LPDGTGVLLTGGSGAGKTTTAVRIGCSGGRVIGTDRSFLLRHAGEWLVVGLPETTRLGL
                     GGARTLGLLGLVEGRVLSREQTLLARAGASGKEAKLTLSNGEMTELLNCGYTPAATADS
                     IVVLSGSPLTSATRMEDLAPAEAHRALREHLLAPDPDYRVRWLSPDPAQEDAGSATAEL
                     SALLTRQPARRLTWNPQLHCDERVVPLLTARTDMAPSAAAHRPDRNSGKEVIR*"
     CDS             6507..7633
                     /protein_domains="PF14907"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4948370"
                     /pseudo=False
                     /translation="MTTGPDTVPDVRGPNDAVWDLLVLVALHQGLDEEPDERVEVLRRP
                     DFDHGRLVEQAMRHGLLAALAHFLHQHGLRRTLPARLRNPVLSQLLLNRHRARLLTAEA
                     LRVSAGFEAAGIRAAWTKGVVVQSTLYEGTGVRLYNDIDVMIAPADRSGALKALTELGY
                     APSTRFDPVTQELEKISRAAERVYQMSPDHLPHAHRLTEDTCVPVVCVDVANSFTWHGC
                     PWQVPVDKVLARIESTPVEPGTTLPALSPADMFLFLCLHLFREGWVERTIRTKDVSLAQ
                     FADIARQWRRASPVTRERVAEETREFGLSAPIAWVCAHADQLFATSMVDELGLRATATR
                     AWLASAQGSSGLELRWPGDMERRLRSGEAPVLSPP*"
     CDS             complement(7674..8824)
                     /protein_domains="PF02771"
                     /protein_domains="PF08028"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4948371"
                     /pseudo=False
                     /translation="MENADALVSLLAANAAKVDAEAEFPVENLNALRESGYLGLLVPTD
                     YGGMGGGLDDMVKVARSLATGCLSTAMIWAMHCQQTDVLVRHADAGLCAELLPRVAAGE
                     VYLASVTTDANKGGHLLAAQDSLAHRGELLTLQRDAPVVTGGVHADGFLITMRAHQEAR
                     EHEVTLVYANRQDLSVQQTHEWRTLGMRGTHSVGLRLSGQVPAHHVVGESGRFREVAAD
                     SMVPIGHLGWSACWLGAAQGAFTRLVRKLAASAHKGGTDLSSPLVQERVARIRLDLELV
                     SAYLSKVREEVSTLREGGQRLDAPSVQIHLNTLKLAASELTFQAADRMVQLAGLSTGYS
                     GDSPIPLERVFRDLRSAALNYANDRLLTANGALSMLDRAVTLV*"
     CDS             complement(8852..9741)
                     /protein_domains="PF08282"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4948372"
                     /pseudo=False
                     /translation="MKSEPESPSAASESRRLRYAVFDLDGTILGPSQRFLPGVAEGLHR
                     LRAQGLRPLLVTGRSVRSFRSLDPSTPELRMFDDPLLLSNGNVLWDRGADSVTVSRALP
                     AEITARLACADVAHTVTETASGLIAVSRRAALAYARAYGVRRKDIVTGALAADHRAEDA
                     VAVTVFGAEADLTEQLTGLPHDLDRISAFGALVVRPERTCKAAAVHEHVRRRYGESHGL
                     SATVAFGDARNDACLLGSAALGVAVPGADQVAARHSDERLSGPLGEYLARFVADRAITA
                     AGVDRDGRALRCPHL*"
     CDS             complement(9829..9959)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MHCSRTGHTDWNTTGTGSQEISVAPTRPLAAIDRQEDDKNRDI"
     CDS             9955..10409
                     /protein_domains="PF01243"
                     /protein_domains="TIGR03618"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4948373"
                     /pseudo=False
                     /translation="MHELGDNVSTKSTRVAVPESHRDLLERPLFAHLATIRPDGTPQVN
                     VMWFDWDGSHLYFTSTTARYKHRNIVRNPAVSVSFHDPDNPYRHLEVRGTVERIDPDSE
                     GGFWLGLAARYGDLVDGPPADVLNRVVYVVRPTVVTSFVRRHPGSVR*"
     CDS             complement(10457..11460)
                     /protein_domains="PF02195"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4948374"
                     /pseudo=False
                     /translation="VKDLMTADWFPELTEIAVVELPVSFLEAADSPRLRGIDEEHALAL
                     AESDSSLPPIMVHRPTMRIIDGMHRVQAARIKGCDTVPAIFFDGSDAEAYVLSVKINTR
                     HGLPLSRADRRAAVARVSALYPQWSDRAIAEMVGVSPKTVGTIRSMGAGDVPSNGRRVG
                     RDGRVRPLNSALGRERIRMAIASDPGASLRQLAEAAGVSPNTVRRMRKTIQSAQDTKPG
                     DETGPAAVTDAPAPQVRQTDSVAGLPSPRAGSDQLPLCVSWALLSRDPSLRSTEAGRLL
                     LRGLSMQSLGPETWERLSNSIPAHRISDVAQLARQCADTWHTFAQRLEVGTRK*"
     CDS             complement(11520..12859)
                     /protein_domains="PF00668"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4948375"
                     /pseudo=False
                     /translation="MEKISVHFEGKRGAIAPLTWAQRRTWRGSHFKHRPFVCVHPVPSG
                     KSLDDVSETVKWALEEFESLRTTFPVGADGEPFQKVEKTGSAEILVMPTEESTVEADIR
                     SVIRRFKGERFDVTAEFGALFVVMTCADVPMRLICLVSHLGVDGHGCQALRVALGNHIS
                     GEHDGPSAPSTQPIDRAQLEQSPKWQEKSARSLEYWKSVLERLPQDEGRSAVMDSRALR
                     GAVSVISNKHAKSASVVYLAAVSVVAGALIGRDKSSFTLPASNRLTQEERSFVGELVQF
                     APGILESLDLPFEAIVDDAWKASTKGYRFSRYDEQALQQMLVELDEGSEYKRDFDFSFN
                     DMRNSTQGESYGGAVSRIRDLVKETKIEPRDHVYQGGTRFLSFALRGDSNEVLSIAVHD
                     SYFPEIPVQRILLAIEALLVGVAVEDPEPLDSPLRFARNCLTSPRLF*"
     CDS             13235..13377
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4948376"
                     /pseudo=False
                     /translation="MADTSAEVFLRAGFHQVPVLLKNTADLGYPALLRMPVTEHALPEP
                     SA*"
     CDS             13639..17333
                     /protein_domains="PF00664"
                     /protein_domains="PF00664"
                     /protein_domains="PF00005"
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4948377"
                     /pseudo=False
                     /translation="MLRRRKALALTLLGAVLGSASMIAMPMVVRQIIDGAILTGGSALW
                     LWLTLLLVLGAATAGFEFLRRLSGARLALEVEFDLRSAMHSRLQSMDAENLDRMPTGQL
                     VGRANADTSLVQGLLNYFPFLGSDALRVALAIGVMLVLSPSLAVVSIVVVPMVLAVSYR
                     MRRKMFPATWDAQQRVGEVVQTVDEVLNGVRVVKAFGQEQREVERVAEASQAVFGSQMR
                     LVRLQARYQPVLQAIPVFGQVAILAYGGWLALRHEITLGTFLAFSSYVAQLVPPAGRLA
                     RLPVIAQQARAGLERIFQLIDLRPAIADAPGATELPALRGDISFSGVHFSYREGAEVLR
                     GLDLHIPAGSRVALVGPSGSGKSTAVALVSRIHDPQHGAVLVDGHDLRNVTLRSLRSQV
                     GVAFEESFLFSASVRDNIAYGCPRAGDADIEQAARAAGAHDFIMGLPHGYDTVVGERGQ
                     RLSGGQRQRVALARALLYDPRILILDDATSAVDAATEEVIHDALREATAGRTTVLVAHR
                     RSTLRLADRIVVMDQGRVVDVGTHDELVERDALYRTLLGELDGDAADGGTEAPASPSGT
                     DAEATERDERHRPGQGDHGLGRRSTVEVPPELLDRVAALDPVRDIAAVNLETEARRDPS
                     FSLVGLLSEFRHLLLLGLLLVVLDALASVIGPYLVKHGINSGVTAGSEAALFTASGVYL
                     VVALAGLIDEIAGTFVTGKTAQRVMLSLRIRIWAQLQRLSLDFYEGEMAGRIMTRMTTD
                     VNQFESLIENGVLSAIVSLVTFVGVGTTLLFLNPELEAVMLPVFVPLALATVLYRRRGR
                     IRYDRARERIAAVNADFQESLSGVRESQAFVHEEIAEARYRRLGHDYVAARLSAQRLML
                     VYFLFVEFLSDATRVIVLGVGAGMVVSGQLTAGALIAFILYIDLFFSPVQQLSQVFDSW
                     QQTRISVNRIAELMKVDSLTPSPENLEETGPLIGEVVFDDVHFSYPTKAPVSPAGPPEA
                     LRGISLRIAAGETVALVGETGAGKSTLMKLLARFYDPSEGAVRVDGHDLRALDLSSYRR
                     RLGYVPQEAFLFTGSVRDNIAYGRPGATDAEVEAATRAVGAHDFVSGLPGGYECEMAER
                     GRSLSAGQRQLIALARAELVDPVLLLLDEATANLDLGTEARVTAAMRRVSRGRTTILIA
                     HRLQTARTADRIVVLDGGRIIETGPHEELLARGGKYASMWQAFETAGHAGGNTALEMRA
                     LRSPSG*"
ORIGIN
        1 tcacatagcc gtgtagccgg cgtccaccat gaggttcgtg ccggtgatgt agctcgcctc
       61 cgcggacagc aggaagacca ctgatgccgc gatctcctcc ggatcggccg tcctgcccag
      121 cagatgtcgg cctccgatct ccggggcccg gtccgcttgc tcccgggtca ttcccagcac
      181 ttctcggtgg aagcgttcgt tgttctcgtt ccacaccgtg ccggggttga cggcgtttac
      241 cctgatgttg tcggaggcga gttccaaggc catacatcgg gtcatgttca cgaccgcgcc
      301 cttggtcgtg ctgtaggtca tgagaccggc ctgcgcgatg tgccccgaaa tcgaggcgat
      361 gttgacgatc gatccgccac ccgccgcttt catgaaaggt gccgagtgct tcacgcacag
      421 cgcctggccc atgatgttga cgtccatcac gcgccgccat tcgtcgaccg tcgcctcgac
      481 accgcgcatg atgaaagcgg cggcgcagtt gatcaggaag cgcacgctcc cgaaggactc
      541 gacggcggct gcgaccgcgc gctccaccga ttcctcgtcc gacacgtcgg tccgtacgaa
      601 gcgggtgacg ggtgagccga cccgactgtt tatctcttcg gccgccgcct tcccgtactc
      661 ctcgttcaca tcggcgatca gcacatgagc gccttcttcg acgagtctgt ccaccacggc
      721 tctgccgatt ccctgggcgc cacccgtgac gatcgcggac tgacctgaga gccctcgcat
      781 tcatgctcct ctacgtggtg tccccggcga gaaatgatca gcggttaggg acggttgcca
      841 cggatattcg tctttgaaat tcgtaaagcg ctccgccgat tcaacagcga atctcttgcc
      901 gaccgcttgt cggatgcttg ccgctctcat gccggcgcgt tcgggcgcgg cgccggtggg
      961 cagccgaacg gtcacgggac gactcgactc acatgggcag ccccgatccg gactgtgcaa
     1021 ttgaggaaac ttcgcagttg cacaaccctt gagcgcaccc ctgcgaaccc agccggcgca
     1081 cggacggctt ccggatccag tggcgttccg gcgtccttca ggggcacgac ccgccggctg
     1141 gtgcaggcgg tcgtcggcgt gggccggtcg gttgttccgg cgtcggcggg ccatgcggtc
     1201 cgccgcagcc actgcggcgg accgccacga acgtgatgcc tcgtacgggc ggacaggggg
     1261 ctaattccgt agcttccggt gcccccgtcg gctcctggcg gagaccatgc cctcagtccg
     1321 ccccaccaca gccgggtcaa ccgctgacga gggcgaccag cgactcccgg tccgtcttgc
     1381 cgttcgaggt cgtgggcagc gcgtcgagca cgtgcagttc cgaggggatc atgtagctcg
     1441 gcagcgcctg cgcgcagtgg gcccgtagct cggccgggcc gacgtccgtg gaccgggcgg
     1501 acgcgacgac gaacgcgccg agacggcgat cgccaccggc ggggccgagg acgagcactt
     1561 ccgccgccat gacgccgggg aactccagca gtcggtgcct gacctcgtcg agttccacgc
     1621 ggttgccccg gatctggacc tgggagtcgg ccctcccgca gaagtacatc tcccctccct
     1681 gtcccatgtg ccccaggtcg ccggtgcgga gaaccacctg actggagcgg ggggaaacgg
     1741 ggtccggaag cagtgccgcc tcagtggcgt ccgggtcgtc ccagtacccc gtgaagaggg
     1801 cgggactgcg caagacgatc tctccgacaa gaccaggacg ctcgatcagc cgccccgcct
     1861 catcgacaag gagcatctcg gcccccttgt gcgcgaaccc tatcgagagc cgcttcgcgt
     1921 cggcgggcag tgggttgggg acctcctcga acgaacaggc catggactcc gtgctgccgt
     1981 agcagttggt cacgcggacc ctcgggagca gctcgcggag gtgacgcagc tccgggagcg
     2041 ggaagtcctc cccgcagaag aggatcccgc gcagccggtc caggtcggcc aggccccgct
     2101 gctcatgccg caggaccggc cgccagatgg atgggacgcc gttcacctgg gtcgctccgg
     2161 tttccttcag tacccgtacg aagcgccgcg gccaccgcag cgattccggt ggaaccgcca
     2221 ccagggcggc accgctgccc agtgccaggc cgaggtttat caaggagaag tcgaactgga
     2281 gcggtgaggt gttggcgacg cggtcatcag gggtcaccag acgctgatcc gccatcccgt
     2341 ggtagaagga cgtgacggcc cggtggctca tcaccacccc cttgggacgt cccgtcgtcc
     2401 ccgaggtgaa tatgacgtac gccgggtcgg tcaccgtcgg ctcccgtcga cggcgtgccc
     2461 ggtcgacggg agcccgctcg atcgtgagcg aggacccttc gaggtgtccc agtcctacgc
     2521 cgaacgggac gtccgcgtca ccggatcccc ggcaccgcag gtagaacgcg ggttcggtgg
     2581 tcctcatgat ggacgccagc cgctgttccg gcggcctctt acccaccgga acgaacgtca
     2641 ggcccagtgc cgagcaggcc agcagagccg cgatggaagc ggccgagaga tccgcctcca
     2701 gaatgacccg gtcaccgatc tcaaggccca gcccgtcgag ggcggccata tggtcgcgga
     2761 cgaggagctc gagttcacga taggtggtga cggcgtaccg ctcggagccg acgggttcga
     2821 tgaccgcagg gcggtcagga agagtgccgg ccatcctgag taggaattcg tgaagaaatt
     2881 cctcccggcc ggtgttcaaa atcccaggaa gtatcgtgcg atcgctcatg gttcctccgc
     2941 gcggtcgtcg gtcctcgtgg agcggtatcg atgcacatcg gcgtgcgaaa tagtccgcgt
     3001 gcggccgaca gcagccgcca ggctacttct tcgtacccgc gtcggcgagt gccgtgccgt
     3061 cggccgaagt cggcaaccgg tacggcgatt gacaggccga agactcgaag agattctgat
     3121 ggcaattcaa gcgggggatg tcgttcggaa ttcattttcg cgatcgcttg cctgcgcgcc
     3181 gtacaggagc agctcgttgt gtgcccagcc gattttccag gttccgcatg cgtcgagttc
     3241 tagtcgttcc gtcatgtatc gcgagaggat ctgcccttgc gggaaccgga aaacgatcag
     3301 ctggaattca gcctgctggg gccgctggag gtgcgcagcg gcggcacgcc gctggatgcc
     3361 ggaccgccca agcgaagagt gctgctcatc cgtctgctcg tggagggcgg ccggacagtg
     3421 agcactgatc gactgcgcaa ggatctgtgg ggctggcacg actcgcctgg cacggtgtcc
     3481 tcgctgcatg cccatatcag cagactccgt gcgctgctgg aaccgtcacg tgcgcatcga
     3541 cggcagggca gcgtgctggt gaccgagccg acgggctacg ccctgcgggt ccgcccccga
     3601 acgctggaca ccgtgcgttt ccaggagggc gcggacgacg cccagcagct catggaggcc
     3661 ggcgacatcg acgcggcgta cgaccgggcc gaggaagcac tcggtcgctg gcgtggaacc
     3721 ccgtacgccg aagcggcgga ctaccgcttc gcggagcggg agatcctcca ccttgaggag
     3781 acccggctga gggtcagcca ggtgcggaca tcggcgttgc tgtcgttgcg ccgcttcgac
     3841 cgggccttgt ccggggcgcg ggagctgacc acggcgcatc ctatggacga gacggcgtgg
     3901 gtcctcatga tgagggccct gtacctgtcc ggccggccgg cagaggcgct ggatggctac
     3961 cagaccatac gggcccggct caatgaggag ggtctggagc ccggtcccgc tctgcgcgcg
     4021 acccagctcg cgatcctccg gcacgacatc gaccggatcg ctcccgcgcc ccggcagcag
     4081 gttgtcctgt cggcccctgc gccccgggag acggcggccg ggtgccgccc gcggctgccg
     4141 tgcagatcgg cggagctgtc ccagctcgcg cgggtgctgg acgtcgcccg gtccggccgg
     4201 gcggcatggg cgctggtctc cggtgagttg ggggtcggga agaccggcct ggtcgaggaa
     4261 ctggccgccc acgccgatgc gctcgggatg cgcacggtct ggactcgcgg ctccgcggag
     4321 tccgacgcgg gtcaggaggc ggatccgttc cgcaccgccg cggagatgct gcgacaactg
     4381 ctcccggagc ggcccctgtc accggactcc ctgccgcctt cgacgacggg tggccccgga
     4441 ggtcacacgc tcggccactt cagggcgttc gaccggatcg cccgtgacct cctgcatgcg
     4501 ctggccgacc gtcccaccct gtgtgtgatc gacgacatgc aacacgtgga cgcggactcc
     4561 cggacgctgc tgacgttcct ggcggttcac cttcggacgg ctcccctcgc cgtcatctgt
     4621 gtctccaggg atttcggtca ggccggtctc gacgggttct ccctgacggt gatgcgcgag
     4681 ggcggctgcc atcttcgtct cgtgccgttc accgcccagg agtcacgcga agtggtgcgc
     4741 cgatggtgcg cgtcgtcccc cacctcgcgg gtagcggcgg cggacgacat cgacctgatg
     4801 gcgcgtgcac tgcattggcg cagcgccggc aatcccctgt ggctgaccga actgctgcgc
     4861 gcggccgtca acaacggcga ctgggccggt gaacggatcc cgcgcgtggc tcatcacatc
     4921 ctcatgtcga tcgcacgagg cctcagacag tccctccggt ccttcctgga gaccgcggcg
     4981 gtcatcgggg aaccggtgga catcctcctg tccgccagtg ttctcggttg ctcggcggag
     5041 gcggtgctgg acctgatcga ggaggctctg accgcgggcc tgctcgtctg gagggacggt
     5101 caggattacg gcgaagcggg gtaccgcttc acctggccgt tgttcaagga ggtggtgctc
     5161 gccgagatgt ccccgctcca aaaacagcgg ctgcggaccg cttcggccgc ccggcgcctc
     5221 gccgacccgc ccggcggacg ggcgagagcg ccgaagcgcc gggcaccccg ctccgccccc
     5281 gaggccacgg tgcgccttac gcctgcccca gcaatggggg agcagcgatg agcgtccacg
     5341 atcaggtcgt cgacctggcg cggggggccg agcccgtcgc cctcgaatgg ttcggcacct
     5401 cgctgcgggt ccacgtccct gtgccagaga cactccagta cgtcgccgac catcaccgag
     5461 tgggtccgcc gacggtcaag gcaccgccat accggtcagc cgccctgttc gccgtcgccg
     5521 ccccgaacat cctggatgag ctcagagatc aggcggcacg cagaaccgtc agccgacgcg
     5581 agtccttcaa gggggtgtgg tacgcctact gggagacggc ggacggtgcg acgatggtgg
     5641 tcgacgagac gcacgcctac cagcacgcgc tgctcacccg tgacttcacg tcgtgggcgg
     5701 tcgtcggcga gcgtcccgaa gacctcgggt tggtcgtcgc ccggacgatc cgcgaactcg
     5761 tccgtgagga cctgctcgcc atgggggccg tcaccttcca cgcctccgcc gctgaactgc
     5821 cggacggtac gggcgtactc ctcaccggcg gctccggggc gggcaagacc accaccgctg
     5881 tccggatcgg ctgctccggc ggtcgcgtca tcggcacgga ccgctccttc ctgctccggc
     5941 acgccggcga gtggctcgtc gtcgggctgc cggagaccac gaggctcggg ctcggcggtg
     6001 ccaggacact cggcctgctc ggtctcgtcg agggacgcgt cctgtcgagg gagcagaccc
     6061 tgctcgcccg cgcgggtgcg tccggaaagg aggccaagct gacgttgagc aacggtgaga
     6121 tgaccgagtt gctgaactgt gggtacaccc ctgcggcgac tgccgactcg atcgtcgtgc
     6181 tcagcggatc gccgctgacc tcggcaacgc ggatggagga cctggccccc gcggaggcgc
     6241 accgggcgct gagagagcat ctactggctc ccgaccccga ctaccgcgtc cgctggcttt
     6301 cccccgaccc cgcccaggag gacgccggtt ccgcgacggc cgagctgtcc gctctgctga
     6361 cacgacagcc ggccagacga ctcacctgga atccgcaact gcactgtgac gaacgggtcg
     6421 taccgcttct gacggcgagg acggacatgg ctccgtccgc tgccgcccac cgccccgacc
     6481 gcaactccgg caaggaggtc atccgatgac gaccgggccc gacactgtcc ccgacgtacg
     6541 cggaccgaac gacgccgtat gggacctgct ggtgttggtg gcgctgcacc agggcctcga
     6601 cgaggagccg gacgagcgcg tcgaagtgct gcggcggccc gacttcgacc acggcagact
     6661 cgtcgaacag gcgatgcgtc acgggctgct ggccgctctc gcccactttc ttcaccagca
     6721 cggcctgcgc cggaccctgc cggcgcggct gcgcaacccg gtcctgtccc agctgctgct
     6781 caaccggcac cgggcccggc tgctgaccgc cgaggcgcta cgggtctcgg cgggcttcga
     6841 ggcagccggg atccgtgcgg cctggacgaa gggggtcgtg gtgcagtcca ccctctacga
     6901 ggggacgggc gtacgcttgt acaacgatat cgacgtgatg atcgcaccgg cggaccggtc
     6961 cggtgctctc aaggcactga ccgagctggg ctacgcgccc tcgacccgct tcgatccggt
     7021 cacccaggag ctggagaaga tctcgcgggc ggcggagcgc gtctaccaga tgtcgccgga
     7081 ccacctcccg cacgcgcacc ggctcaccga ggacacctgt gtgcccgtcg tctgtgtcga
     7141 cgtggccaac agcttcacgt ggcacggctg tccgtggcag gtcccggtcg acaaggtgct
     7201 ggcacggatc gagtcgaccc cggtggaacc cggcacgacg ctgcccgcgc tctcccccgc
     7261 ggacatgttc ctcttcctgt gcctgcatct cttccgtgag gggtgggtgg agcgcacgat
     7321 tcggaccaag gacgtgtccc tggcgcagtt cgccgacatc gcgcgccagt ggaggcgcgc
     7381 ctcgcccgtg acccgggaac gcgtcgcgga ggagacacgg gagttcgggc tgtccgctcc
     7441 gatcgcctgg gtgtgcgccc acgcggatca gctcttcgcc acctcgatgg tcgacgagct
     7501 gggcctgcgg gcgaccgcga cccgcgcatg gctggcgagc gcgcagggaa gctcgggact
     7561 tgagttgcgc tggcccgggg acatggagcg gcgcctgcgg tcgggagagg cccccgtgct
     7621 gtccccgccg tgacgcagga gcgtcgggtg gccctctggg gcacttgcgg cgtcacacca
     7681 gcgtgaccgc gcggtcgagc atcgacagtg cgccgttggc ggtcagcagc cggtcgttcg
     7741 cgtagttcag ggccgctgac cgcaggtcgc ggaagacccg ttcgagaggg atgggtgagt
     7801 cgcctgagta cccggtggac agcccggcca actgcaccat gcggtcggcg gcctggaagg
     7861 tcagctcgga cgccgcgagc ttcagggtgt tgaggtgaat ctgcacggag ggtgcgtcca
     7921 gccgctgacc gccctcgcgc agcgtgctca cctcctcccg caccttggag aggtaggcgc
     7981 tgaccagttc gagatcgagc ctgatacggg ccacacgctc ctggaccagg ggtgaggaga
     8041 ggtccgttcc gcccttgtgg gcggaggctg cgagcttgcg cacaaggcga gtgaaggcgc
     8101 cctgtgccgc gcccagccag caggcgctcc acccgaggtg cccgatcggc accatgctgt
     8161 ccgcggcgac ctcacggaag cgtccggatt cgccgacgac gtggtgcgcg ggcacctggc
     8221 cgctgaggcg caaccccacg ctgtgggtcc cgcgcatgcc gagagtccgc cactcatggg
     8281 tctgctggac cgacaggtcc tgccggttcg cgtacacgag cgtgacctcg tgctcccgcg
     8341 cctcctgatg cgctcgcatg gtgatgagga atccgtccgc gtggacacct ccagtgacca
     8401 ccggtgcgtc ccgctggagc gtcaggagct cgccgcggtg cgccaacgag tcctgggccg
     8461 ccagcagatg gccgcccttg ttcgcgtcgg tggtgaccga cgcgagatac acctcgcccg
     8521 ccgcgacacg gggaagcagt tccgcgcaca ggccggcgtc ggcgtgccgc accagcacat
     8581 cggtctgttg gcagtgcatc gcccagatca tggcggtgga caggcatccg gtggcgagtg
     8641 aacgggcgac cttcaccatg tcgtcgaggc cgccccccat tcctccgtag tccgtcggta
     8701 ccagcaggcc cagatatccg ctctctcgca gcgcattcag attctccacc gggaactctg
     8761 cctcggcgtc caccttggcc gcgttcgcgg ccagcaggct caccagggcg tcggcattct
     8821 ccatcggggt tcctcccctg ttcggcgtgt tcacaggtgt gggcaccgga gcgcacggcc
     8881 gtcgcggtcg acacccgccg ccgtgatcgc ccggtcggcg acgaaccggg ccaagtactc
     8941 acccaggggt ccgctcagcc gctcatcgct gtgccgtgcg gcgacttggt ccgcacccgg
     9001 gaccgccacg ccgagggcgg ccgaacccaa caggcacgcg tcgttgcgcg cgtccccgaa
     9061 ggccacggtg gccgagagcc cgtggctctc gccgtacctt cgccgcacat gctcgtgcac
     9121 agccgccgcc ttgcatgtgc gttcgggcct caccacaagc gcgccgaacg cggagatacg
     9181 gtcgaggtca tggggcagac cggtcagctg ctcggtcagg tccgcctcgg ccccgaacac
     9241 ggtgacggcg acggcgtcct ccgcgcggtg gtcggccgcg agggccccgg tcacgatgtc
     9301 cttgcggcgg acgccgtagg ctcgcgcgta cgccaaggcg gcgcgacgcg agacggcgat
     9361 cagtccgctc gccgtctccg tcaccgtgtg cgcgacgtcc gcgcacgcga ggcgggccgt
     9421 gatctcggcg ggcagcgcgc gggacaccgt caccgagtcg gcgccgcggt cccacaagac
     9481 gtttccgttg ctgagcagga gcgggtcgtc gaacatccgc agttctggcg tggacgggtc
     9541 cagggagcga aaggacctga ccgatcgacc ggtgaccagc agcgggcgga gaccttgggc
     9601 acgcagccgg tgcaggccct cggcgacacc gggcaggaag cgctgcgatg gaccgaggat
     9661 cgtgccgtcg aggtcgaaca ccgcgtaccg gaggcgtcgg ctttccgagg cagccgacgg
     9721 ggattcgggt tcacttttca tctctttcgg cagcccttct cctggccgag ccgcaatacg
     9781 gacgacagca cgttgcgtga tacggcgaca gcgcattccg cgagcaatca aatatctctg
     9841 ttcttgtcgt cctcttgccg atcgatcgcg gcaagaggac gagtcggcgc aacggagatt
     9901 tcttgactgc cggtgcccgt cgtgttccaa tccgtgtgcc ctgtccggct gcaatgcacg
     9961 aactgggaga caacgtgagc acgaaatcca ccagagtcgc ggttccggaa agccataggg
    10021 acctgcttga acgtccgctc ttcgctcatc tggccacgat ccgccccgac ggcacgcctc
    10081 aggtgaacgt gatgtggttc gactgggacg gaagccatct ctatttcacc agcacgaccg
    10141 cgcgctataa acaccgcaac atcgtccgca atcctgccgt ctccgtctcc tttcacgacc
    10201 cggacaaccc gtaccggcac ctagaggtac gtggaaccgt ggagcgcatc gacccggaca
    10261 gcgagggcgg gttctggctc ggcctcgcgg cccggtacgg ggacctcgtc gacggcccgc
    10321 ctgccgacgt cctcaaccgg gtcgtctatg tcgtgcgtcc cacggtggtc acctcgttcg
    10381 tccgcagaca cccgggctct gtgcgctgag cgggaccgag ggggcggcgc ggccatggcc
    10441 caccgcccgc gaaccctact tccgcgtccc cacctcgaga cgttgcgcga acgtgtgcca
    10501 ggtatcggcg cattgccggg caagttgtgc aacatcagat atacggtgcg cgggaatgga
    10561 gttgctcagc cgctcccagg tctccgggcc cagcgactgc atgctcagtc cacgcagcag
    10621 aaggcggccg gcctccgtcg accgcaagga cgggtcccgg ctgagcagtg cccaggaaac
    10681 gcagagtggc agctgatccg agcccgcccg cggtgagggc aggccggcga cactgtccgt
    10741 ctgtcgcacc tgcggagccg gagcgtcggt cacggcagcc gggccggtct cgtcgccggg
    10801 tttcgtgtcc tgggcgctct ggatcgtctt ccgcattctg cgcaccgtgt tcggcgagac
    10861 tcccgccgcc tcggccagtt gccgcagcga cgcgccaggg tcggaggcga tcgccatgcg
    10921 gatgcgctcg cggcccaacg cgctgttcag ggggcggacc cggccgtccc tgccgacccg
    10981 gcgcccgttg gagggaacat ccccggctcc catggagcgg atcgtgccga ccgtcttcgg
    11041 ggacaccccc accatctcgg ctatggcccg gtccgaccac tgcgggtaga gcgcggaaac
    11101 gcgtgcgacc gcagcccgtc ggtcggcgcg cgacagaggc aggccgtgcc gggtgttgat
    11161 cttgacactc agtacgtacg cttcagcatc gctgccgtca aagaagatgg cggggacggt
    11221 gtcgcagccc tttatccgtg ccgcttgcac acgatgcatt ccgtcgatga ttcgcatcgt
    11281 aggccggtga accatgatgg gcggaagcga tgagtcgctt tccgcgaggg ccagcgcgtg
    11341 ctcctcgtct atgccgcgga gacggggcga gtcggctgcc tctaggaagc tgaccgggag
    11401 ttcgactact gcgatctcgg tgagttcagg aaaccagtcg gccgtcatga gatctttcac
    11461 cactactccg gttggggccc gatacgccgc tcaaagtgtc agggttcgga attaagcctc
    11521 agaaaagtct cggggaagtc aggcagtttc tcgcgaatcg caggggggaa tcgagcggct
    11581 ccgggtcctc cacagccact ccgaccagaa gagcctcgat cgccagcaaa atacgctgaa
    11641 cagggatctc cgggaagtac gagtcgtgaa cagcaatcga gagcacctca ttgctgtcgc
    11701 cgcgcagggc gaacgacaga aaacgagtcc caccttgata cacatgatca cgcggttcga
    11761 ttttggtctc tttcacgaga tcccgaatcc gacttactgc cccgccgtac gactctcctt
    11821 gcgtggagtt ccgcatgtcg ttgaatgaga agtcgaaatc tcttttgtac tcgctgcctt
    11881 cgtcgagttc aacgagcatc tgctgaagag cctgctcgtc gtagcgactg aatcggtaac
    11941 ccttggtgct tgccttccag gcgtcgtcga cgatggcctc aaaaggcagg tcgagcgatt
    12001 cgagtatccc aggggcaaat tgaaccagct caccgacgaa ggagcgctct tcctgagtca
    12061 agcgattgga ggccggcaac gtgaacgagg acttgtcccg cccgatgagc gcgccggcca
    12121 ccactgaaac agcagccagg tagaccacgg acgcactctt ggcgtgctta ttcgagatga
    12181 ccgagacggc acccctcagc gcgcgagaat ccatgaccgc cgaccggccc tcgtcctgcg
    12241 gcaacctttc cagaaccgac ttccagtatt cgagggagcg cgcgctcttc tcctgccact
    12301 tcggtgattg ttccagctgc gcccggtcga tcggctgagt cgaaggcgcc gacggaccgt
    12361 catgctcccc ggaaatgtgg ttgccgagcg ccaccctcag cgcttggcaa ccatgaccgt
    12421 caaccccgag atgggaaacc agacaaataa ggcgcatggg gacgtcggcg caggtcatta
    12481 cgacgaacag ggccccgaac tcggcggtga catcgaagcg ctcacccttg aagcggcgta
    12541 tcacactccg aatatcggcc tctaccgtgg attcctcggt tggcatgacg aggatctccg
    12601 ccgatccggt cttctcgacc ttctggaaag gttcaccatc ggcacccact ggaaacgtcg
    12661 ttcgcagcga ctcaaactcc tcgagcgccc atttgacggt ctcactgacg tcatcgaggc
    12721 ttttcccgga cgggacagga tgaacgcaca cgaatggccg gtgcttgaag tgagaccccc
    12781 gccaggtcct tcgttgcgcc cacgtaagag gtgcgatcgc gccacgcttg ccctcgaagt
    12841 gaaccgatat tttttccatt tcggatcctc atgaaccgga gacgtctctg aagcaacctt
    12901 tcaaatgccg agttggtggc atgttacatc taatccgaac ggaaagcgct tgtcaatacc
    12961 gtattcactt caagatcttt caaattttta ctaaagtctg gccgtcgtgg gtttgctgta
    13021 cgccgcgtga actcatgcac cgcaaatccg acatcggtac ctctctgtac cttttggaca
    13081 gctctccttc tctgctgtgg gggcgatctt ggaaaggccc tcgccactgt gtaagatccc
    13141 cattcccgtg cacctgccga atccctgggt cccggtgggg gcatcgtcga gtgatggaca
    13201 atccttcgac ggtagatggg aggaaaagcc ggtatggcgg atacctcggc ggaggtgttc
    13261 ctgcgtgccg gattccacca ggtgccggtt ctcttgaaaa acacggccga cctcggctac
    13321 ccggccctgc tccggatgcc ggtcacggag cacgccctac cagaaccgag cgcctgagcc
    13381 gcgtcatcca ctcgaacggc gatgaccggc gctcagttgc gtacgcctcc cagctttctg
    13441 ccatgcccgc ctcataaagc ccgccagcta tccgacagac aggagtacca gtggagaaga
    13501 ctgtgcttac ggggcgtcag gctggacgcg gcggtggacg accgtcccgc cgagcgccgc
    13561 gtcgccaggc ggagcgcgag tcgacgtccg ctgaaccatc ggccggtcct ggatggggcc
    13621 gacgcctgtg gggatgcatg ctccggcgcc gcaaggcact ggcgctcacc ctgctgggcg
    13681 cggtactcgg cagcgcctcc atgatcgcca tgcccatggt cgtgcggcag atcatcgacg
    13741 gcgccatcct taccggtggg tccgcactgt ggctgtggct gaccctgctc ctcgtgctcg
    13801 gggccgccac ggcaggcttc gaattcctcc gccgtctgtc gggagcccgc ctcgctctcg
    13861 aagtcgagtt cgatctgcgc agcgccatgc acagccgtct tcagtccatg gacgccgaga
    13921 acctcgaccg catgccgacg gggcaactcg tcggcagagc caatgcggac acatccctgg
    13981 tccagggact gctcaactac ttcccgttcc tgggcagcga cgcgctgcgg gtggccctgg
    14041 cgatcggggt gatgctcgtc ctgagcccgt ctctggccgt tgtcagtatc gtcgtcgtgc
    14101 ccatggtgct cgctgtctcc taccgaatgc gccggaagat gtttcccgcg acatgggacg
    14161 cccagcagcg ggtgggagag gtcgtccaga ccgtcgacga ggtcctcaac ggggtgcggg
    14221 tcgtcaaggc cttcggccag gagcagcggg aagtcgagcg agtggccgag gcatcgcagg
    14281 cggtcttcgg ttcccagatg cgcctggtgc gactgcaggc ccgctaccag ccggtcctgc
    14341 aggccattcc cgtcttcggg caggtggcca tcctggccta cggcggctgg ctggcgctgc
    14401 gccacgagat cactctgggc acgttcctgg ccttctccag ctacgtcgcc caactcgtgc
    14461 cccccgccgg ccggttggca cgcctccccg tcatcgcgca gcaggccagg gccggtctgg
    14521 agcgcatctt ccagctcatc gacctgcgtc ccgccatcgc cgacgcaccc ggcgcgacgg
    14581 aactgcccgc tctccgcggc gacatcagtt tctccggggt gcacttctcc taccgggagg
    14641 gagccgaggt cctgcgcggc ctcgacctgc acataccggc cgggtcccgc gtcgccctcg
    14701 tcggcccgag cgggagcggc aagtcgaccg cggtggcgct ggtgtcgcgc atccacgacc
    14761 cgcagcacgg tgccgtgctc gtcgatggcc acgacctgcg caacgtcact ctgcgctctc
    14821 tgcgcagtca ggtcggcgtg gcgttcgagg agagcttctt gttctccgcg tcggttcggg
    14881 acaacatcgc ctacgggtgc ccgcgcgccg gtgacgccga catcgaacag gcggcacgcg
    14941 ccgcgggtgc gcacgacttc atcatgggcc tgccccatgg ctacgacacc gtggtgggcg
    15001 agcggggcca gcgcctgtcg ggcgggcagc ggcagcgggt ggccctggcc cgggcgctgc
    15061 tgtacgaccc ccggattctg atcctcgacg acgcgaccag cgcggtggac gccgccaccg
    15121 aggaggtcat ccacgacgcg ctgcgcgagg cgacggccgg gcggaccacc gtcctggtcg
    15181 cgcaccgccg ctcgaccctg cgtctggcgg accggatcgt ggtcatggac cagggccggg
    15241 tcgtcgacgt cggcacccac gacgagctgg tggagcgcga cgcgctgtac cggacgctgc
    15301 tcggggagct cgacggggac gccgccgacg gcgggaccga ggcaccggcc tcgccgtccg
    15361 gcacggacgc ggaggccacg gagcgggacg agaggcatcg gcccggccag ggcgaccacg
    15421 gcctcggccg ccgcagcacg gtggaagtac ctcccgaact gctggaccgc gtggccgcac
    15481 tcgaccccgt gcgcgacatc gcggcggtga acctggagac ggaggcacgc cgggacccct
    15541 cgttcagcct ggtcgggctc ctatcggagt tccggcacct gctcctgctg ggcctgctcc
    15601 tggtcgtcct cgacgccctg gcttcagtga tcggccccta cctggtcaag cacggcatca
    15661 acagcggcgt gacggccgga tccgaggccg ccctgttcac cgcgtcgggc gtgtacctgg
    15721 tggtggccct ggccggtctg atcgatgaga tcgccggcac gttcgtgacc ggtaagaccg
    15781 cccagcgcgt catgctgtcc ctgcggatcc ggatctgggc ccagttgcag cggctgtccc
    15841 tcgacttcta cgagggggag atggccgggc ggatcatgac ccggatgact accgacgtca
    15901 atcagttcga gtcgctgatc gagaacggcg tactgtccgc gatcgtctcg ctcgtcacgt
    15961 tcgtcggcgt ggggacgacg ctgctcttcc tcaatcccga actggaagcc gtcatgctcc
    16021 ccgtcttcgt cccgctggcc ctcgcgacgg tgctgtaccg gcggcggggc cgcatacgct
    16081 acgaccgagc cagggaacgg atcgccgccg tcaacgcgga cttccaggag agcctgtccg
    16141 gggtacgtga atcccaggct ttcgtccacg aggagatcgc cgaggcccgg taccggcggc
    16201 tcggccacga ctacgtcgcc gcccgtctct cggcccaacg gctgatgctc gtctatttcc
    16261 tgttcgtgga gttcctctcg gacgccacgc gcgtcatcgt cctgggcgtg ggcgccggaa
    16321 tggtcgtgtc cgggcagctg accgcgggcg ccctgatcgc cttcatcctc tacatcgacc
    16381 tgttcttctc tcccgtccaa cagctgtcgc aggtcttcga ctcgtggcag cagacccgga
    16441 tctcggtgaa ccgcatcgcc gagctcatga aggtcgacag cctcaccccc agcccggaga
    16501 acctcgagga gacgggcccg ctgattggtg aggtggtctt cgacgacgtg cacttctcct
    16561 atccgaccaa ggcgcccgtc tcgccggccg ggccacccga ggcgctgcgt ggcatcagcc
    16621 tgcgtatcgc ggccggcgag acggtcgccc tggtgggcga gaccggcgcg ggcaagtcga
    16681 ccctcatgaa gctgcttgca cggttctacg atccgagcga gggtgccgta cgcgtcgacg
    16741 gccacgatct gcgcgcgctc gacctgtcct cgtaccggcg gcgtctcggc tatgtgccac
    16801 aagaggcgtt cctgttcacc ggatcggtcc gcgacaacat cgcttacggt cgtcccgggg
    16861 ccaccgacgc cgaggtcgag gcggcgacgc gggcggtcgg cgcccacgac ttcgtctccg
    16921 ggctgcccgg cggctatgag tgcgagatgg cggaacgcgg ccggtccctg tcggcgggac
    16981 agcgccagct catcgccctg gccagggccg agctggtcga ccccgtcctg ctcctgctgg
    17041 acgaggccac ggccaacctc gacctcggca ccgaagcccg ggtcaccgcc gcgatgcggc
    17101 gcgtctcgcg cggccggacc acgatcctga tcgcgcaccg cctgcagacg gcgcggaccg
    17161 cggaccgcat cgttgtcctc gacggcggcc ggatcatcga gaccgggccg cacgaggagt
    17221 tgctcgccag gggcgggaag tacgcctcga tgtggcaggc cttcgaaaca gctggccacg
    17281 ccggggggaa caccgcgctc gaaatgcgcg ctttgcgttc gccgagcgga taa
//
