LOCUS       reptomyces_RBGC_299271 15618 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_299271
VERSION     Streptomyces_RBGC_299271
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000721105.1
  ORGANISM  GCF_000721105.1
            .
FEATURES             Location/Qualifiers
     CDS             2..303
                     /protein_domains="PF13510"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903542"
                     /pseudo=False
                     /translation="VNSPLDLARARPGPAFTVTLDGREIEALPGQTVAAALWAAGITSW
                     RTTRGEGRPRGIFCGIGVCFDCLVTVNDRPNQRACLVPLQPGDAIRTQEGTGHDD*"
     CDS             297..1729
                     /protein_domains="PF07992"
                     /protein_domains="PF04324"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903543"
                     /pseudo=False
                     /translation="MTERPHLAVIGAGPAGLAATLAAAALGVRVTLLDSATEAGGQFYR
                     QPAAELRAARPQALHHQWRTWEHLRDGLRTHVRTGAVRHLTDHHVWFVERRPAEEPEPR
                     PAKGAERFTVHALLGPEQEEPVEVPADAMLLATGGYEKVLPFPGWTLPGVVTAGGAQAM
                     LKGALAVSGRRAVVAGTGPLLLPVATGLAAAGVEVAALVESADPKAFVRRSRALAAQPG
                     KVAEGARYTARLLRHRVRTLVHHTVVEAHGTDRVEAVTVAALDATGRVEPGTERRIRCD
                     TLAVGHGMLPHTDLAETLGCRLDGLRVHVDDEQRTDVPGVWAAGETTGIGGAALSLAEG
                     HIAGHCAAARLHGTAPDPRAWAAAARTRTRLREFSAALDGAYAPPAHWAEQVTDDTVVC
                     RCEEVTGGAIRAAVTELGAGDPRTVKLLTRAGMGWCQGRMCGPAVAGLAGCDLTPSRRP
                     FARPVPLGVLAHAGESEDD*"
     CDS             1821..2716
                     /protein_domains="PF00701"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903544"
                     /pseudo=False
                     /translation="MTATETRSWRGVLVATALPLREDLSVDYDRYAEHCAWLVENGCDG
                     VVPNGSLGEYQVLTPEERARVVETAVAAVGGARVMPGVAAYGSAEARRWAEQARDAGCQ
                     AVMLLPPNAYRADERSVLAHYAEVAKAGVPIVAYNNPIDTKVDLVPEMLAKLHGEGFVH
                     AVKEFSGDVRRAYRLAELAPELDLLIGADDVLLELAIAGAKGWVAGYPNALPAANVALY
                     RAAVDGDLGTAKKLYEQLHPLLRWDSQVEFVQAIKMSMDLVGRYGGPVRPPRVPLLPEQ
                     EAVVRAATERALAAGLG*"
     CDS             2778..3778
                     /protein_domains="PF05544"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903545"
                     /pseudo=False
                     /translation="MRSKLVLHAVDSHTEGMPTRVITGGIGTIPGATMNERRLYFREHR
                     DDIKQLLMNEPRGHSAMSGALLQPPTRPDCDWGVVYIEVSGYLPMCGHGTIGVATVLVE
                     TGMVEVVEPVTTIRLDTPAGVVVAEVAVENGAAKAVTLANVPSFSVALDREIALADGRT
                     VTYDMAYGGNFYAILPLEQFGLPFDRARKDDILKAGLSLMEAINAEEEPVHPEDPTIRG
                     CHHVHLLAPGSTARHSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLHTEFLNES
                     FIGTHFTGRLLGTTEVAGRPAVLPSFTGRAWITGTAQYLLDPADPFPAGFVL*"
     CDS             3853..4544
                     /protein_domains="PF07729"
                     /protein_domains="PF00392"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903546"
                     /pseudo=False
                     /translation="MAAQRTSAPVAVAPALPVLGGKKSSYRERVADALRAALIAGELRP
                     GEIYSAPTLAARFGVSATPVREAMLDLVKEGLVDTVPNKGFRVTAVSEKQLDEYTHIRA
                     LVEIPTVVGLATTADPVSLEALRPVAREIVRAAAAGDLIAYVEADTRFHLGLLALAGNA
                     HLVEVVGDLRGRSRLYGLTALLEAGRLTASAEEHLELLDALTARDKDAVREVMTRHLGH
                     VRGLWAAK*"
     CDS             complement(4592..5394)
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903547"
                     /pseudo=False
                     /translation="MLDVRGLKKVYEGSGRRVEAVRDLTFTVGAGELVCLVGPSGCGKT
                     TLLKCVGGLLAPTAGEVLLEGRQVTGPPPAMAFVFQEYGRSLFPWMRVRENVELPLKQK
                     NLAKDRRRELVADALRSVDLADAAGAYPWQLSGGMQQRVAIARALAYEPRVLLMDEPFA
                     AVDAQTRADLEDLVRRLWRERAITILFVTHDIDEAVYLGERVVVLSASPTVVQEQLKVD
                     LPDERDQLHTRVAPRFAELRTHVYEQIQAAKRGGGTTKSDAPQPL*"
     CDS             complement(5416..6194)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903548"
                     /pseudo=False
                     /translation="VRRFLLRLVFVVALPVVLLAVWWLASDDSTDVYWPPLRTILKTFP
                     DVWTAERLRTDAFPSVLRLAAGYATAAVTGVALGTVIGSHRRVRAVCEPVMEFLRAVPP
                     PVLIPVIMLFAGIGDTMKVVVIASGCVWPILLNTVEGVRAVDSVMADTARSYGITGAAR
                     LRHVVLRSASPQIFAGLRQGLSIGIILMVISEMFAASSGLGFTVVQFQRGFAIPDMWTG
                     ILVLGLLGFLLSVLFQLVERRVLGWYHGLRASTRRSR*"
     CDS             complement(6192..6964)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903549"
                     /pseudo=False
                     /translation="VKGANLALGAAGLAVFLALGEAVPRLGLVKEAYFPPTSKIADAFA
                     GELTDSAFWTALGDTLTGWAVGLAVAACAGIVAGVVISVVPYLREATASTIEFLRPIPS
                     VALIPLAVLLYGNELRSVLLLVVYASFWQVLIQTLYGVRDVDPVAEETARSYGLGTWAR
                     VRYVLWPTALPYVMTGLRLAAAVALILTVTAELVIGSPGLGARIGIAQNSQAVPDMYAL
                     IVVTGLLGLLINVGARSVERRALAWHQSVRGEVTV*"
     CDS             complement(6962..7932)
                     /protein_domains="PF09084"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903550"
                     /pseudo=False
                     /translation="MRRLLSGLTAGAILLATAACGSSDDSGTSGKAASSGGITTVKLGL
                     IPIVDVAPVYLGQKKGFYEKHGLKLTLTTAQGGAAIVPGVVSGQFQFGFSNVTSLMVAQ
                     SNNVPVKAVVNGIASTGVRGKDFNALMVKKGSALKSPGELEGKKVAINTLKNINETAVR
                     AAVRTAGGDPDKVRFVELAFDQMPAALDQGQVDAVSVVEPARATVRSQGGVEIASPLID
                     VAPDLTVAMYFTSRQYEQQHPDVVKKFREATAESLAYADSHPDEVRAIVTSYTKIPAAV
                     LEQVTLPKWPAEANRASIEALRKLGQDDGLFKTEPDLDKLLP*"
     CDS             complement(8115..9049)
                     /protein_domains="PF00111"
                     /protein_domains="PF00175"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903551"
                     /pseudo=False
                     /translation="MTVYESELVVEKKEFAADGVLALTLRHPLGEELPAWEPGAHVDVV
                     LGPDLERQYSLCGDPADRTAWRIAVLREPDGRGGSAYVHEQLGQGGKVRVRGPRNHFAL
                     RPAPRYRFVAGGIGITPILPMLAAAEAAGAEWSLLYGGRSRGSMAFCEELSGYGDRVTI
                     APQDETGLLDLASVLDDLPEGTLVYCCGPGPLLDAVEARCPAGALHVERFEPKVQETGA
                     DTEFEVELARSGRTLTVPADVSVLDAVRGAGVEVLFSCTEGTCGTCETDVLEGDPDHRD
                     SVLSDEEREAGETMLICVSRCRGKRLVLDL*"
     CDS             complement(9047..9228)
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_3903552"
                     /pseudo=False
                     /translation="VTSPSSAGPREIYRIDWLPGTDVLHGTCHCGAENSAQDPVEMWEW
                     MLGHPEGHQPRGSDS*"
     CDS             complement(9226..10292)
                     /protein_domains="PF00355"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903553"
                     /pseudo=False
                     /translation="MPHMTAFARNQWYVAAYSHEVGREELLGRTILGEPLVFYRTEEEG
                     TPVVLHDRCVHRRYPLSESRLDGDRIVCGYHGFTYDTTGTCVYVPGQKRVPRTARVTSY
                     PVVEQDSLVWVWIGDPALADPQTIPRARHLDSPGWTTVRGMEPIDADYGLLVDNLLDLS
                     HETYLHGGYIGTPEVAETPITTEVDEGAGIVRVSRHMDDAACPPFYAKSTGIEGRITRW
                     QDIEYHAPCLYLLHSRIAPVGVLPEADGSDPNGFHTEITYAITPSADGKVYDFWMVSRD
                     WATEDDEVTEFLRGNNHTVVMQDVDALNLLQKTLGTERTGYQELSINIDTGGLAARRIL
                     ARLVEEGDKPVEKVQ*"
     CDS             11468..12471
                     /protein_domains="PF00528"
                     /protein_domains="TIGR01726"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903554"
                     /pseudo=False
                     /translation="MSESPGIAVSSGAAPPTEAILRPDTPAAPKPLAAQRVLPLRHPGR
                     WTITAVVLVLVAQIVHGLATNPFFQWDRFQYWFLRPTILDGLLITLEVTVYSAALGLLG
                     GVLLALARLSPSPVLRTVSWIYTWLFRSVPLIVVLLFLYNFSALYRTLSVGVPFGPAFF
                     TFDESRLATDMVVAVVGLSLNEAAYASEVVRGGILSVDQGQHEAASALGLPKRYQFAKI
                     VFPQALRSITPNYVNQLIGLIKGTSLVFYVSLLDLFGSVQSMGSTYPGDIVPLLLVATA
                     WYLILTSVVSVIQFYVERYYSRGALRTLPPTPLQKVRTALRDLRARVRRETAT*"
     CDS             12469..13361
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903555"
                     /pseudo=False
                     /translation="MTAKATETAQTAETAQTPETAQTASAAETARTASAAETGATHEIR
                     PAAVEVHDVHKWYGTHHVLDGVELTVRPGEVTVILGPSGSGKSTLLRVINHLEKPEIGH
                     VSLNGELIGVRRHGERLKELSERVILAQRGRIGFVFQNFNLFPHLTVLDNVAAAPVATG
                     RLTKPEAQKLARDLLARVGLADKAAAYPRQLSGGQQQRVAIARALALRPGVILFDEPTS
                     ALDPELVGEVLAVIKDLAGSGTTLVIVTHEIGFAREIADRVVFMDEGRIVEQGPPAQVL
                     DHPDNERTRDFLSKVL*"
     CDS             13499..14523
                     /protein_domains="PF00497"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903556"
                     /pseudo=False
                     /translation="MRTLSLRSRLLRGVTASAAVASLAAGLAACGGDSDAATKTGSASA
                     GTVTVGALSNGAAEETELKVSEVKSISAELPKAVARSGKLVVGVGALPAGFPPLAYVGQ
                     DQKTLTGAEPDLGRLVAAVLGLKPELKNSTWENLFVGIDSGKVDVAFSNVTDTEERKKK
                     YEFASYRQDNLAFEVPKKSTWNFDGDYENLAGKTVSVGAGTNQEKLLLEWKAKLAKEGK
                     KLTVKYFQDNNSVYLALSSGKIDAYFGPNPGIAYHITQVARTPNPTRNAGEFSGAGATL
                     QGIIAATAKKDSGLAKPLADAVNYLIKNGQYAKWLAAWHLSNEAVGKSEINPPGLPLDN
                     S*"
     CDS             14553..15391
                     /protein_domains="PF08445"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903557"
                     /pseudo=False
                     /translation="VSTAEFRARPAAFQLRRLRNAMSTSVDHAPPPSPTEPHILDNAAW
                     AALAGPHSHLAERVGRAARYPADVSPFTALEDPTDPRAWEDLATLVGPGAVTPVTAVQT
                     VPVGWQVEQSGEGVQMIATALYAEPAPEAVRLGPADVPEILELIALTRPGPFLPRTVEL
                     GTYLGIRDHGRLIALAGERLRPPGWTEISAVCSHPDHRGRGLATRLVRAIAAGIRERGD
                     TPFLHAAASNTHAIRLYESIGFTLRRRTRFALVRAPGGQLETQGRDGQEAGQPEEEA*"
     CDS             15503..15618
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3903558"
                     /pseudo=False
                     /translation="MRPVSPHRAMKPAPPRRLHLYSRQHIDLLRVAGALCRP*"
ORIGIN
        1 gtgaactccc ccctcgacct ggcccgtgcc cggcccggtc ccgccttcac ggtcaccctg
       61 gacggccgtg agatcgaggc gctgcccggc cagaccgtcg ccgccgcgct ctgggcggcc
      121 gggatcacct cctggcgcac cacccggggc gagggccgtc cgcgcgggat cttctgcggg
      181 atcggcgtct gcttcgactg cctggtgacc gtcaacgacc gtcccaacca gcgcgcctgc
      241 ctggtgcccc tgcagccggg cgacgcgatc cgcacacagg aggggaccgg acacgatgac
      301 tgaacgaccg catctcgcgg tgatcggcgc gggcccggcg ggactcgccg cgaccctcgc
      361 ggcggcggcc ctcggggtac gcgtcacgct cctcgactcg gcgacggaag cgggcgggca
      421 gttctaccgg cagcccgccg ccgaactgcg cgccgcgcgc ccgcaggccc tgcatcatca
      481 gtggcgcacc tgggagcacc tgcgggacgg cctgcggacc cacgtccgga caggcgccgt
      541 acgccacctg acggaccatc atgtctggtt cgtcgagcgg agaccggcgg aggaacccga
      601 gccgcgaccg gcaaagggcg ccgaacgctt caccgtgcac gccctcctcg gccccgagca
      661 ggaggagccc gtcgaggtgc ccgccgacgc catgctcctg gcgaccggcg gctacgagaa
      721 ggtcctgccc ttccccggct ggaccctccc cggcgtcgtc accgcgggcg gcgcccaggc
      781 catgctcaag ggcgccctcg cggtgtccgg ccgcagggcg gtggtcgccg ggaccgggcc
      841 gctgctgctg cccgtggcga ccgggctcgc cgcggccggc gtcgaggtgg ccgcactcgt
      901 cgagtccgcc gacccgaagg cgttcgtacg acggtcccgc gcactggcgg cgcagcccgg
      961 caaggtcgcc gaaggcgcgc ggtacacggc ccggctgctc cggcaccggg tgcgcaccct
     1021 ggtccaccac accgtcgtcg aggcgcacgg caccgaccgg gtggaggcgg tgacggtcgc
     1081 cgcgctcgac gccacaggga gggtcgagcc cggcaccgag cgccgtatcc gctgcgacac
     1141 cctcgccgtc ggtcacggca tgctcccgca caccgacctc gccgagaccc tcggctgccg
     1201 cctcgacggg ctgcgcgtcc acgtcgacga cgaacagcgc accgacgtcc ccggcgtctg
     1261 ggccgccggc gagaccaccg gcatcggcgg cgcggccctc tccctcgccg aggggcacat
     1321 cgccggccac tgtgccgcgg cccgcctgca cggcaccgca cccgacccgc gcgcgtgggc
     1381 ggcggccgcg cggacccgta cccggctgcg ggagttctcc gccgcgctgg acggcgcgta
     1441 cgcaccgccc gcccactggg ccgagcaggt caccgacgac accgtcgtct gccgctgcga
     1501 ggaggtcacc ggcggcgcga tccgggcggc cgtgacggaa ctcggcgccg gcgacccgcg
     1561 gaccgtgaag ctgctgacac gggccgggat gggctggtgc caggggcgga tgtgcgggcc
     1621 cgcggtcgcc gggctcgccg ggtgcgacct cacaccgtcg cggcggccgt tcgcccggcc
     1681 ggtaccgctg ggggtgctgg cacacgcggg ggagtccgag gacgactgac atccccaccc
     1741 acccacccac ctactgcttc tttccctctg tcctcagtcg tccagtgaaa tgtcacaccc
     1801 tatcgagatg ggacccgaga tgaccgccac cgagacccgc tcctggcgcg gcgtgctcgt
     1861 cgccaccgcg ctcccgctgc gcgaggacct ctccgtcgac tacgacaggt acgccgagca
     1921 ctgcgcctgg ctggtcgaga acggctgcga cggcgtcgtc ccgaacggct cgctcggcga
     1981 gtaccaggtg ctcacccccg aggagcgggc cagggtcgtc gagacggccg tggccgccgt
     2041 cggcggcgcc cgggtgatgc ccggcgtcgc cgcctacggc tccgccgagg cccgccgctg
     2101 ggccgagcag gcacgagacg cgggctgcca ggccgtgatg ctgctgcccc ccaacgccta
     2161 ccgtgccgac gaacggtccg tcctcgccca ctacgcggag gtggcgaagg cgggcgtgcc
     2221 gatcgtcgcg tacaacaacc ccatcgacac caaggtcgac ctcgtgccgg agatgctcgc
     2281 caagctgcac ggcgagggct tcgtccacgc ggtcaaggag ttctccggcg atgtccgccg
     2341 cgcctaccgg ctggccgaac tcgccccgga actggacctg ttgatcggcg ccgacgacgt
     2401 cctgctggag ctcgccatcg cgggcgccaa gggctgggtg gccggctacc cgaacgctct
     2461 gcccgccgcg aacgtcgccc tgtaccgcgc ggcggtcgac ggcgacctgg gcacggccaa
     2521 gaagctgtac gagcagctgc accccctcct gcgctgggac tcccaggtcg agttcgtgca
     2581 ggccatcaag atgtccatgg acctcgtggg ccggtacggc ggaccggtgc gcccgccgcg
     2641 ggtcccgctg ctgccggagc aggaggcggt cgtccgggcc gccaccgaga gggccctcgc
     2701 cgccggactc gggtaggtct ccgggcacca cggcacccgg cttccagcgt ccccgtagcg
     2761 aatcaccagg agtgtcatgc gcagcaagct cgtcctgcac gccgtcgact cgcacaccga
     2821 gggcatgccc acccgggtga tcaccggcgg tatcggcacg atccccggcg cgaccatgaa
     2881 cgagcggcgt ctgtacttcc gtgagcaccg cgacgacatc aagcagctcc tgatgaacga
     2941 gccgcgcggt cactcggcga tgagcggtgc cctcctccag ccgcccaccc ggcccgactg
     3001 tgactggggt gtcgtctaca tcgaggtctc cggctatctg ccgatgtgcg ggcacggcac
     3061 catcggggtg gcgaccgtgc tggtggagac cgggatggtc gaggtcgtcg agccggtcac
     3121 cacgatccgg ctcgacaccc cggccggggt ggtggtcgcc gaggtcgcgg tggagaacgg
     3181 cgccgcgaag gccgtcaccc tcgccaacgt cccgtccttc tccgtcgccc tggaccgcga
     3241 gatcgcactg gccgacgggc ggacggtgac ctatgacatg gcctacggcg gcaacttcta
     3301 cgccatcctg ccgctggagc agttcggcct gcccttcgac cgcgcccgca aggacgacat
     3361 cctgaaggcc ggtctgtccc tcatggaggc gatcaacgcc gaggaggagc ccgtccaccc
     3421 cgaggacccc accatccgtg gctgccacca cgtccacctg ctcgcccccg gctccacggc
     3481 ccgccactca cggcacgcca tggcgatcca ccccggctgg ttcgaccgct caccctgcgg
     3541 caccggtacc agcgcgcgca tggcgcaact gcacgcccgc ggtgaactgc ccctgcacac
     3601 cgagttcctg aacgagtcct tcatcggcac gcacttcacc ggccgtctcc tcggcaccac
     3661 cgaggtggcc ggccgccccg cggtcctgcc cagcttcacc gggcgtgcct ggatcaccgg
     3721 caccgcccag tacctgctgg acccggccga cccgttcccg gcgggattcg tcctgtagac
     3781 gccgacgaca atgacgggac cacgccacca tgacgggtac cgcatgacac cgcacagcta
     3841 ggagacgtcc catggccgcc cagcgcacca gcgcccccgt cgcggttgcc ccggccctgc
     3901 ccgtgctggg cggtaagaag agcagctacc gggagcgggt cgccgacgcc ctgcgggccg
     3961 cgctgatcgc cggcgaactg cgcccggggg agatctactc ggcgccgacg ctcgccgccc
     4021 gcttcggcgt ctcggcgacg ccggtgcgcg aggccatgct ggacctcgtc aaggagggcc
     4081 tggtcgacac ggtccccaac aagggcttcc gggtcaccgc ggtctccgag aaacagctcg
     4141 acgagtacac ccacatccgc gccctcgtcg agatccccac ggtggtgggc ctggccacga
     4201 cggccgaccc ggtgtcgctg gaggcgctgc ggccggtcgc ccgggagatc gtgcgggccg
     4261 ccgcggccgg cgacctcatc gcgtacgtcg aggccgacac ccgcttccac ctcggactgc
     4321 tcgccctcgc cggcaacgcg cacctggtgg aggtcgtcgg cgacctccgg gggcgctccc
     4381 gtctctacgg gctcaccgcc ctcctggaag cgggccgtct gacggcctcc gccgaggaac
     4441 acctcgaact cctcgacgcg ctgacggccc gggacaagga cgcggtccgc gaggtgatga
     4501 cccgccacct cggacacgta cggggactgt gggccgccaa gtagcccgta cggcggcggc
     4561 cggttccggc ggccggttcc gccgcccggc tcacagcggc tgaggcgcat ccgacttggt
     4621 cgtcccgccc ccgcgcttcg ccgcctggat ctgttcgtac acatgggtcc gcagctctgc
     4681 gaagcgcggg gccacgcgcg tgtgcaactg gtcccgctcg tccggcagat cgaccttgag
     4741 ctgttcctgc acgacggtgg gggaggcgga cagcacgacc acccgttccc cgaggtagac
     4801 ggcctcgtcg atgtcgtggg tgacgaacag gatggtgatt gcgcgctccc gccacagccg
     4861 ccgtaccagg tcctccaggt cggcccgggt ctgggcgtcc accgccgcga acggttcgtc
     4921 catcagcagc acccggggct cgtacgccag cgcccgggcg atggccaccc gctgctgcat
     4981 gcccccggac agctgccagg ggtacgcccc ggccgcgtcc gcgaggtcca ccgaccgcag
     5041 cgcgtcagcc accagctccc gacgccggtc cttggccagg ttcttctgct tcagcgggag
     5101 ttcgacgttc tcccggaccc gcatccaggg gaacaggctg cggccgtact cctggaagac
     5161 gaaggccatg gcgggcggcg gcccggtcac ctgccgcccc tccaggagca cttcgcccgc
     5221 cgtcggcgcg agcagcccgc cgacgcactt cagcagggtc gtcttgccgc agcccgacgg
     5281 gccgacgaga cagaccagtt cgcccgcgcc gacggtgaag gtgaggtcgc gcaccgcctc
     5341 cacccgccgc ccggagccct cgtagacctt cttcaggccg cgtacgtcga gcatgccctg
     5401 ccctttctcg gacgtcacct ggaccgccgg gtggaggcgc gcagaccgtg gtaccagccg
     5461 agcacccgcc gctcgaccag ttggaacagc accgacaaca ggaagcccag cagacccagc
     5521 acgaggattc cggtccacat gtcggggatc gcgaaaccgc gctggaactg cacgacggtg
     5581 aagccgaggc cgctgctggc cgcgaacatc tcgctgatga ccatgaggat gatgccgatg
     5641 gacagcccct ggcgcagccc cgcgaagatc tgcgggctcg ccgagcgcag caccacgtgc
     5701 ctgaggcggg cggcgcccgt gatgccgtag gaacgggccg tgtccgccat caccgagtcc
     5761 accgcccgta cgccctcgac ggtgttcagc aggatcggcc acacgcagcc gctcgcgatc
     5821 acgaccacct tcatcgtgtc gccgatgccc gcgaacagca tgatgacggg gatcagcacg
     5881 ggcggcggca ccgcccgcag gaactccatg accggctcgc acaccgcccg cacccgccgg
     5941 tgggaaccga tcaccgtgcc gagggccacg ccggtcacgg ccgcggtggc gtaaccggcc
     6001 gccagtctga gcacgctggg gaaggcgtcc gtgcgcagcc gctcggccgt ccagacgtcc
     6061 gggaaggtct tcaggatggt gcgcaggggc ggccagtaca cgtcggtgct gtcgtcggag
     6121 gccagccacc acacggcgag caggacgacg ggcaacgcga ccacgaacac cagccgcagc
     6181 agaaagcgcc tcacaccgtc acctccccgc gcaccgactg gtgccaggcc agcgcccggc
     6241 gctccaccga cctcgcgccg acattgatca acaggcccag gagaccggtc acgacgatca
     6301 gcgcgtacat gtccggcacg gcctgcgagt tctgcgcgat cccgatgcgc gcgcccaacc
     6361 ccggggaccc gatgacgagt tcggcggtga cggtgaggat cagggcgacg gccgccgcca
     6421 gcctgaggcc cgtcatgacg tacggcagcg ccgtcggcca caggacgtac cggacccgcg
     6481 cccaggtgcc cagaccgtac gagcgtgcgg tctcctcggc gaccgggtcg acgtcccgga
     6541 cgccgtacag cgtctggatc agcacctgcc agaacgaggc gtacaccacc agcaggagca
     6601 ccgagcgcag ttcgttgccg tacagcagga ccgccagcgg gatcagcgcg accgagggga
     6661 tcgggcgcag gaactcgatc gtcgaggcgg tcgcctcccg cagatacggc acgacggaga
     6721 tgaccacccc cgcgacgatc cccgcgcagg ccgccaccgc caggcccacc gcccagccgg
     6781 tgagcgtgtc gccgagcgcc gtccagaagg cggagtcggt gagttcgccg gcgaaggcgt
     6841 cggcgatctt gctggtggga gggaagtacg cctccttgac caggccgagc cgcggcaccg
     6901 cctcgcccag ggcgaggaag acggcgagcc cggccgcacc gagtgcgagg ttcgcgccct
     6961 tcacggcagc agcttgtcca ggtcgggctc cgtcttgaac aggccgtcgt cctggcccag
     7021 cttccgcagc gcctcgatgg aggcgcggtt cgcctcggcc ggccacttcg gcagcgtcac
     7081 ctgctccagc accgcggccg ggatcttcgt gtacgacgtg acgatggcgc ggacctcgtc
     7141 cgggtgggag tcggcgtacg cgagggactc cgcggtggcc tcccggaact tcttcaccac
     7201 gtccgggtgc tgctgttcgt actgccggga ggtgaagtac atcgcgacgg tgaggtccgg
     7261 ggcgacgtcg atcaaagggg aggcgatctc cacgccgccc tggctcctga cggtggcccg
     7321 cgccggctcg accacactca cggcgtcgac ctgtccctgg tcgagagccg cgggcatctg
     7381 gtcgaaggcg agctcgacga acctcacctt gtccgggtca ccgccggcgg tgcgtaccgc
     7441 cgcgcgcacg gcggtctcgt tgatgttctt gagcgtgttg atggcgacct tcttgccctc
     7501 aagctccccg ggtgacttga gggcactgcc cttcttcacc atgagggcgt tgaagtcctt
     7561 gccccgtacg ccggttgagg cgatgccgtt gacgacggcc ttgacgggca cgttgttgga
     7621 ctgggccacc atcaacgacg tcacattgct gaacccgaac tggaactgac cactcacgac
     7681 acccggcacg atcgccgcgc cgccctgtgc ggtcgtgagg gtcagcttca gtccgtgctt
     7741 ctcgtagaag ccctttttct ggccgagata gacgggcgcc acgtcgacga tggggatgag
     7801 ccccagcttg acggtggtga tgcccccgga cgaggcggcc ttgcccgacg taccggagtc
     7861 gtcggaagag ccacaggccg ccgtggcgag aagaatggca ccggccgtga ggccggataa
     7921 aagacgacgc atggctcctc ctgtgcagac aacggtgttc cgacaggttg tgcgcacccc
     7981 gcacagtagt gctcagccgg tgtgcggggg aacgtgaagg gagccatccg tcactgtcaa
     8041 agggtgtgac cggcaaggcg gttgacagcc gggaggggcg ggcaggaggg caggacgtga
     8101 tgccccccgg ggatcacagg tccagcacga gccgcttccc ccggcaccgg gacacacaga
     8161 tgagcatggt ctcgccggcc tcgcgttcct cgtcggagag aaccgagtcc ctgtgatcag
     8221 ggtcgccctc cagcacgtcc gtctcgcagg tgccgcacgt tccctcggtg caggagaaca
     8281 gcacctccac gccggcgccc cgcacggcgt ccagcaccga cacgtccgcg ggcacggtga
     8341 gcgtacgacc gctgcgggcc agctcgacct cgaactcggt gtcggccccc gtctcctgga
     8401 ccttcggttc gaaccgctcg acgtgcaacg ccccggccgg gcagcgcgcc tccaccgcgt
     8461 ccagcagcgg cccgggaccg cagcagtaga cgagggtgcc ctcgggcagg tcgtccagca
     8521 ccgaggcgag gtccagcagt ccggtctcgt cctggggggc gatcgtgacg cggtcgccgt
     8581 acccgctcaa ctcctcgcag aacgccatgg atccgcggct gcgcccgccg tacagcaggc
     8641 tccactcggc gcccgccgcc tcggccgcgg ccagcatcgg caggatgggc gtgatgccga
     8701 tgccgcccgc gacgaaccga tagcgcggcg cgggccgcag tgcgaagtgg ttgcgcggac
     8761 cgcgcacccg caccttgccg ccctgcccca actgctcgtg cacgtacgcg gatccgccgc
     8821 gcccgtccgg ctcgcgcagc acggcgatcc gccaggccgt ccggtccgcc ggatccccgc
     8881 acagcgaata ctgccgctcc aggtccggcc cgaggaccac gtcgacatgg gcgcccggct
     8941 cccaggccgg cagttcctcg cccagcggat gccgcagggt cagggcgagc acgccgtcgg
     9001 cggcgaactc ctttttctcg acgacgagtt cggattcgta cacagtcatg agtcgcttcc
     9061 tcgcggctga tggccctccg ggtgcccgag catccactcc cacatctcga ccgggtcctg
     9121 ggcggagttt tcggcaccgc agtggcaggt gccgtgcagt acgtcggtcc caggcagcca
     9181 gtcgatgcgg tagatctctc gcggccctgc cgaggacgga ctcgtcactg gaccttctcc
     9241 acgggcttgt cgccctcctc gaccagccgg gcgaggatac ggcgggcggc caggccgccg
     9301 gtgtcgatgt tgatgctcag ctcctggtag ccggtccgct cggtgccgag cgtcttctgc
     9361 agcaggttga gcgcatcgac gtcctgcatg acgaccgtgt ggttgttgcc ccgcaggaac
     9421 tcggtgacct cgtcgtcctc ggtcgcccag tcccgcgaga ccatccagaa gtcgtacacc
     9481 ttgccgtcgg cggacggcgt gatggcgtac gtgatctcgg tgtggaaccc gttcgggtca
     9541 ctgccgtcgg cctcgggcag cacaccgacc ggcgcgatcc ggctgtgcag cagatacaga
     9601 cagggcgcgt ggtactcgat gtcctgccag cgggtgatcc ggccctcgat gccggtggac
     9661 ttggcataga acggcgggca cgccgcgtcg tccatgtgcc ggctcacccg gacgatcccg
     9721 gcgccctcgt ccacctcggt ggtgatcggc gtctcggcga cctcgggagt gccgatgtag
     9781 ccgccgtgca ggtacgtctc gtgggagagg tcgaggaggt tgtcgacgag gaggccgtag
     9841 tcggcgtcga tcggctccat gccgcggacg gtcgtccagc cgggggagtc caggtgccgg
     9901 gcccgcggaa tggtctgcgg gtcggcgagg gccgggtcac cgatccacac ccacaccagg
     9961 gagtcctgct cgaccaccgg gtacgaggtg acgcgggcgg tgcgcggtac gcgcttctgc
    10021 cccggcacgt acacgcaggt gccggtcgtg tcgtaggtga acccgtggta cccgcacacg
    10081 atccggtcgc cgtcgagccg gctctcggag agcggataac ggcggtgcac acagcggtcg
    10141 tggaggacga cgggcgtgcc ctcctcctcg gtccggtaga acacgagcgg ctcaccgagg
    10201 atcgtccggc ccagcagttc ctcgcggccg acctcgtggc tgtaggcggc gacgtaccac
    10261 tggttcctgg cgaaggcggt catgtgaggc atgggggttc ccgtccctgt cggcggggct
    10321 tcgtcgcccc gcgtgccgtg gttggactca ggatcgtgac gcttgcggtg gctcggcaag
    10381 gcggcttctg ccacacggaa ggcttcctgc ggagaggctg gtcagagcgc cggtccgcac
    10441 caacctccgt ggcgtgcggg ggtggttccg gcctgactgg tgatcgttct gccggtgagt
    10501 gactggctcg acgggccgcg aggtgtacgc gccgagtttt atggctgtcc gctgcccgcg
    10561 ctgtcctcag ggtgctcgag ctcggcacga ggtgctcaca gacgcatggc tcgcggcgga
    10621 cagggcggcc ctgtggtgtc gctcgtcgcg tgatgtcgct gccccggaac ctccgctcgg
    10681 cgtcgtacgc gtcgacaacc ggcacagaac gcggtctgtg ccggcgaacg ggtacggctc
    10741 cgttgccacc ggtggcggat cagtgagcgc tggagacccg cgacagatcg atgtgcaggc
    10801 gcctcgtcaa gtcgttccag ggcattccca ccggtcccgc ctccggggct cgcgcagggc
    10861 gagaccacgc ttgccccgcc gcaccggcgg aacccggtcg tcacccgggg caccccgtcg
    10921 cggtggaagg gttgcctgtc agcgggccgg ggccgatgac cacatgagcg gggcgaaccc
    10981 gcgccgtggg cgctgacaat cgtgaccgtc cacgtcagtt tcgggccgct ccatgacgcc
    11041 gtcaagaagg ccgagtgggc ggtctcacct ggtggtcact cgcgttgaca ttattttcgg
    11101 gacatgccta acttgcggcg aagagcgaga tgccccaggg ccggacaagt gatggtgaca
    11161 gcgatgtacg cagctgacgg gacggccgca tggcggcgcc tcggtcgcgt cctgctgtgc
    11221 gcggaccgct ccgtcgacct gctgcgcgtc aacagcgccc tctgtacggc cgcttgtcgc
    11281 gcccgttgtc agggctgacg gctttctgag tctctgacga ccaccgctgt gcggtgtgtc
    11341 ccctccccgc ccagcccccg ttccgcgtgt acccgtctcg cgcctcgtgc ctcgggccga
    11401 gccgttcccg cggcatggtg ctgccgcttt ccgcggtcct gggtgttcga atccctggag
    11461 ccttccatga gtgaatctcc cggcatcgct gtgtcctccg gagcagcgcc gcccactgag
    11521 gcgatcctcc gccccgacac ccccgccgcg ccgaagcccc tggcggcgca gcgagttctt
    11581 ccgctccggc atcccggccg ctggaccatc acggcagtcg tactcgtgct ggtcgcccag
    11641 atcgtccacg ggctggcgac caaccccttc ttccaatggg accggttcca gtactggttc
    11701 ctgcggccga cgattctcga cggcctgctc atcaccctcg aagtcaccgt ctacagcgcc
    11761 gcgttgggcc tgctcggcgg cgtcctgctg gcactggccc ggctctcccc gagcccggtg
    11821 ctgcgcacgg tcagctggat ctacacctgg ctgttccggt cggtgccgct gatcgtggtc
    11881 ctgctgttcc tctacaactt cagtgcgctc tacaggacgt tgagtgtggg agtgccgttc
    11941 ggcccggcct tcttcacctt cgacgagtcc cggctcgcca ccgacatggt cgtcgcggtg
    12001 gtcggactga gcctcaacga ggcggcgtac gcctccgagg tggtgcgcgg cggcatcctc
    12061 tccgtcgacc agggccagca cgaggcggcc tccgccctcg gcctgccgaa gcggtaccag
    12121 ttcgcgaaga tcgtcttccc tcaggcgctg cgctccatca cgcccaacta cgtcaaccag
    12181 ctgatcggcc tgatcaaggg cacctcactg gtcttctacg tctcgttgct cgaccttttc
    12241 ggctccgtac agagcatggg cagcacctac cccggcgaca tcgtgccgct gctgctggtc
    12301 gccaccgcct ggtacctgat cctcaccagc gtcgtgtccg tcatccagtt ctacgtcgag
    12361 cggtactact cgcggggcgc gctgcgcacc ctgccgccga ccccgctgca gaaggtgcgg
    12421 accgctctgc gtgacctgcg ggcccgggtc cggagggaga cggcgacatg accgccaagg
    12481 cgactgagac agcgcagacg gccgagacgg cgcagacgcc cgagacggcg cagacggcat
    12541 cggcggccga gacggccagg acggcatcgg cggccgagac cggcgcgacg cacgagatac
    12601 gtcccgccgc ggtcgaggtg cacgacgtgc acaagtggta cggcacccat cacgtcctgg
    12661 acggtgtgga gttgaccgtg cggcccggag aggtcacggt catcctcgga ccctccggct
    12721 ccggcaagtc cacgctcctg agggtgatca accacctgga gaagcccgag atcggccatg
    12781 tcagcctgaa cggcgagctg atcggcgtac gcaggcacgg cgaacgcctg aaggaactga
    12841 gcgaacgggt catcctggcc cagcgcggcc ggatcgggtt cgtgttccag aacttcaacc
    12901 tcttcccgca cctgaccgtg ctggacaacg tggcggcggc tccggtggcg accggcaggc
    12961 tgaccaagcc cgaggcccag aagctggccc gcgacctgct cgcccgcgta gggctcgccg
    13021 acaaggccgc cgcctacccc cggcagttgt ccggcggcca gcagcagcgg gtggccatcg
    13081 cccgcgccct cgccctgcgg cccggggtca tcctcttcga cgaacccacc tccgccctcg
    13141 accccgagct ggtcggcgag gtgctggccg tcatcaagga tctggccggc agcggcacca
    13201 ctctcgtcat cgtgacccac gagatcggct tcgcccgtga gatcgccgat cgggtggtct
    13261 tcatggacga aggccggatc gtcgaacagg gcccacccgc ccaggtgttg gaccacccgg
    13321 acaacgagcg caccagggac tttctgagca aggtcctctg accccgacga ccgcgtccag
    13381 cgggcccgca catctgcgcc cgctgtgcac aacggctccg cggcactccg ccccgagccc
    13441 gcgctccgcc ggaccgctct gcccacacat ctcaccgcac acccgacaag gacacccatg
    13501 cgcaccctca gcctccgcag cagactcctc cgcggcgtca ccgcgtccgc agccgtcgcc
    13561 tccctcgccg cagggctcgc cgcctgcggg ggcgacagcg acgccgccac caagaccggc
    13621 agcgcgtcgg ccgggacggt caccgtcggc gcactctcca acggcgccgc cgaggagacc
    13681 gagctgaagg tgtccgaggt gaagtcgatc agcgccgaac tgcccaaggc ggtcgccagg
    13741 agcggcaagt tggtcgtcgg tgtcggcgcg ctgcccgccg ggttcccgcc gctggcgtac
    13801 gtgggccagg accagaagac cctcaccggc gccgaacccg acctcggccg gctggtcgcc
    13861 gcggttctcg gactgaagcc ggagttgaag aactcgacct gggagaacct gttcgtcggc
    13921 atcgacagcg gcaaggtcga cgtggccttc tcgaacgtca ccgacaccga ggagcgcaag
    13981 aagaagtacg agttcgcctc ctaccggcag gacaacctcg ccttcgaggt gccgaagaag
    14041 agcacctgga acttcgacgg cgactacgag aacctggccg gcaagaccgt ctccgtcggg
    14101 gccggcacca accaggagaa gctcctgctg gagtggaagg cgaagctggc caaggagggc
    14161 aagaagctca ccgtcaagta cttccaggac aacaacagcg tctacctggc gctgtccagc
    14221 gggaagatcg acgcctactt cggtcccaac cccggcatcg cctaccacat cacccaggtc
    14281 gccaggacgc ccaacccgac gcgcaacgcg ggcgagttct ccggcgcggg agcgacgctc
    14341 cagggcatca tcgcggccac cgcgaagaag gacagcggcc tggccaagcc gctcgcggac
    14401 gcggtcaact acctgatcaa gaacggtcag tacgccaagt ggctcgccgc ctggcacctc
    14461 tccaacgagg ccgtcggcaa gtccgagatc aacccgcccg ggctgccgct cgacaactcc
    14521 tgatccgccg cccgtccctg gagactccgc cgtgtccacg gcggagttcc gggcgcgccc
    14581 tgccgcgttc cagctacgga gactccgcaa cgccatgtcc accagcgtcg atcatgcacc
    14641 gccccctagc ccgaccgaac cgcacatcct ggacaacgcc gcctgggccg ccctggcggg
    14701 cccgcactcc catctcgccg agcgcgtcgg ccgggccgcc cgctaccccg cggacgtctc
    14761 cccgttcacc gccctggaag accccaccga tccccgcgcc tgggaggacc tggcaacact
    14821 ggtcggaccc ggcgccgtca ccccggtcac cgcggtccaa accgtgcccg tcggctggca
    14881 ggtcgagcag agcggcgagg gagtccagat gatcgccacg gcgctgtacg ccgaacccgc
    14941 acccgaagcg gtacggctcg gacccgccga cgtacccgag atcctcgagc tgatcgccct
    15001 caccaggccg ggccccttcc tgccccgtac cgtcgaactc ggcacctacc tcggcatccg
    15061 ggaccacggg cggctgatcg ccctggccgg cgaacgcctc cgcccgccgg gctggaccga
    15121 gatcagtgcc gtctgcagcc acccggacca ccgcggccgc ggcctggcca cccggctggt
    15181 ccgcgcgatc gcggcgggga tcagggaacg tggcgacacc cctttcctcc acgccgcagc
    15241 gagcaacacc cacgcgatcc ggctctacga gtccatcggg ttcaccctgc gccgccgcac
    15301 gcggttcgcg ctcgtccgcg cgccgggcgg acagctggag acgcaaggcc gggacggaca
    15361 agaagccgga cagccggaag aagaggcata gccgtgctgt tgtgcttgct gacgagcgga
    15421 tggcgcccct tcggggagcc gctggagcga ggccgaccca gaccccgggg tcgccgggcc
    15481 ggaagggcgg aggtgcggca catgcgtccc gtgtccccgc accgcgccat gaaacccgcc
    15541 ccgccccgcc gcctgcacct gtactcccgg cagcacatcg acctgctgcg ggtggccggc
    15601 gcgctctgtc gcccctga
//
