LOCUS       reptomyces_RBGC_301370 16089 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_301370
VERSION     Streptomyces_RBGC_301370
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001280065.1
  ORGANISM  GCF_001280065.1
            .
FEATURES             Location/Qualifiers
     CDS             2..2388
                     /protein_domains="PF07228"
                     /protein_domains="PF08448"
                     /protein_domains="PF13581"
                     /protein_domains="PF01590"
                     /protein_domains="PF13426"
                     /protein_domains="TIGR00229"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522640"
                     /pseudo=False
                     /translation="MSPDEPFDDGVAARAVIAVDGTLTEWSEGARRLLGHTADEVVGRP
                     AAALLADGADPPSVRDGSRWSGTLTLRHRDGHPVSLWVLAHRRPPDGAEATDWLAVSPP
                     EAADQGLGDDPLVRLALTQSPCATMIFDERLRLRGLNDAMADLLGLPAARMLGLKPTDI
                     GSRPQNAELEEYLRRVLSTGRRQEMQTYMKATGESRGAHAWLARMAPLTDGTGRVRGVC
                     VTAHDFSDQYRSRERLLLVNEASVRIGTTLDVTRTAQELADVCVPALADFVSVDLLDPR
                     DHGGESAGPPIPPLSLRRSAHQSVNKGSPEAVAKPGQVDVYPENSPQAASLVAGHTVVA
                     SGASGDLERWLAWDPVRFQRIQEYGIHSTMSVPLQARGTTLGVAVFTRFRRPEPFTPDD
                     VLLAEEVTARAAVCIDNARRYSRERETTLTLQRSLLPRTLPHTAAVEAASRYLPATRSG
                     VGGDWFDVIPLSGMRVAMIVGDVVGHGIQASATMGRLRTAVRTLADIDLAPDELLTHLD
                     DLVVRLSEESGGDDGTGEVGATCLYAVYDPVSRRCTLARAGHPLPLLVPPGGPARQLDL
                     PSGPPLGVGGLPFEAAEVELREGSILVFHTDGLLVSRERDVDTSGRMLREALSASSGSL
                     DETCDRVLNTLLPPGGSSDDVALLLARTRGLPSAQVATWDIPADPALVAPIRKQVVDQL
                     ERWGLLEATFTAELVVSELVTNAIRYGAPPIRLRLIHDAATLICEVSDTNHTAPHLRRA
                     KTWDEGGRGLLLVAQLTQRWGSRHTGEGKTIWAELALLGDEL*"
     CDS             2550..3778
                     /protein_domains="PF02040"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522641"
                     /pseudo=False
                     /translation="VTLLATVLIWAVARPKGLPEAVLAVPAAGLAIALGVISPEHAGEE
                     IQRLGPVVGFLAAVLVLAHFCDVEGLFTACGAWMARWAAGRPTRLLTAVFALASVITAV
                     LSLDATVVLLTPVVLATATRMGVQARPHLYACAHLSNTASLLLPVSNLTNLLAFTASGL
                     SFTRFAALMALPWLVAIAAEYLVFRRFFDDELAAPVPSPDSDPRPEPLPLFALVTVGCT
                     LAGFVVASAVGIAPAWAATAGALVLAGRALVRRRATPLAVVRSAQPAFLAFVLALGVVV
                     RAVVDHGLADALRHVLPDGSGLVTLLGVAALAAVLANLINNLPAVLVLLPLTAGSGPGA
                     VLAVLLGVNIGPNLTYAGSLATLLWRRIVQQGGHRVGLGEFTRLGLLAVPAALVSAVAA
                     LWLSLAVVGV*"
     CDS             complement(3793..6518)
                     /protein_domains="PF00652"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522642"
                     /pseudo=False
                     /translation="VKDAGPSNSPASARGFGATDEQLSAELRKWTGATPALHPVGELLD
                     RHWEAAFAYARLCTDGPRSAGMLTTAAFTRLFGETLRQNGPTSAWRSHLLLTVRRIAAE
                     WAGDHRSDMLHPALLADTGDGERPASRLLPSRHRRLLSGAFQRLPQSARCLLWHVEVEA
                     EPLSSPAALLGLDEEGARVELDRARDRLREECLQLHRELAPDEECRRYLRLLDVTYRRG
                     GLDIDPDLRAHIEGCGHCSVAADQLDQFNHALGVALSEGVLGWGGRGYAESRIGEAADH
                     TGGGRAAERRRPGAEAGAAAGALAGAARELFPDPVALAREVFPEPAGMAYEIMPDPARA
                     AREGFAGPASGEGLAEPAGEVRDGFPASPRAARRAFPGPARAARKGVTNPVRAAREGFA
                     GPRGAGGEVSPGPADAAREGFAGPAGGEGLAESAGEAREGFPASPRAARKASTGPARAA
                     RRGGTNTAGAARRSLTDLARAAREGLSGSRAAREGLADPAGATREGLAGPAGRSFPAPP
                     RAAREAFRGQPGDGREVFPDPVALAGAVGESFTEPGGPATAPPPPAGAESRDPAGGTAE
                     AAAGVGRSLPIATVAPAHRSEGSRSAARRSARSGRRAARRVARRRNLTVGILTVSGLVV
                     LPLVLWSTGDSGDSAPAGADRAAGEAPDPDAGERNTDPSRTGAGDARQGALHGRLHNVA
                     SDLCVGVDGDKAVEGAEAELTTCSAEAAQQWTYETDGLLRNGAAPDLCLDSQLGYSVRL
                     APCTGASRPDPKNIRYDFTLQGALVPRWDQDLALAPAATDGSGALVLKARTDDEVQRWV
                     IDTSRADLQVQAVNWNANVPATRTAPAPSPGPTRSRTPAPTPTPSPASPAPEQTPSSPA
                     ATDPSCYRYHCDSDGRYGNPDQGYPGHGYGRGGDGRR*"
     CDS             complement(6891..7843)
                     /protein_domains="PF12833"
                     /protein_domains="PF02311"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522643"
                     /pseudo=False
                     /translation="VRADGLPETVEASHTGQTGKTGSTGNTGDPAPPPGLVVVGHFDQP
                     HGYGVHRPHGSASWLFTWTTAGRGRLWQGGANTSAGAGALVVLAPGVPHGYGVESGAGH
                     WRFWWAHCQARPSWAAWLRPYDAGHGMYLIASVPAGVHGRVGAAFRRMHTDARWTGTEA
                     LPDGAPPDGQVAVAHGSAARELALCALEEIVLLTTARPPAPRPGLDARVRRAQELIDAD
                     PGAPHTVRSLAEGVALSPSRFAHLFSSQLGRSPMRALREARLRHAARLLESTDLPVERV
                     ATASGFVSPFHFNRAFRERYGAPPGAYRATHGGAAG*"
     CDS             7914..8755
                     /protein_domains="PF05721"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522644"
                     /pseudo=False
                     /translation="MTVTGNGAVGASILDREELRRYREEFDGVGFTVVRGLFAAGEIDR
                     LCGEFAALRAAGPVPGHFEPRAVDGPGADPLHVWPRVMHPHEINGLAREVLLDARLRTV
                     LEALLGEEVLAAQSMFYFKPPGARGQALHQDNFYLRVEPGTCVAAWTACDVIDRENGGL
                     EVVPGTHLMDLFCPEQADADVSFAREYVPPPAGLAPVPVDMAPGDVLFFNGSLVHGSQP
                     NRTADRFRRSFIGHYVGRSTERIGRFYRTLAMSGARVELAESEGAGPCGTEFAPQGPH*
                     "
     CDS             complement(8773..9740)
                     /protein_domains="PF00248"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522645"
                     /pseudo=False
                     /translation="MQYVKLGSTGLDVSRISLGCMTYGLPDRGTHEWTLDEEASRPLIR
                     QAVEAGITFFDTANVYSDGTSEEIVGRALRDFARRDEIVLATKVHGRMRPGPNGGGLSR
                     KAIMTELDHSLTRLGTDYVDLYQIHRFDPHTPVEETMEALHDVVKAGKVRYIGASSMYA
                     WQFSKAQYTARLNGWTRFVSMQNHYNLIYREEEREMLPLCADQGVGVLPWSPLARGRLT
                     RDWDTTTRRGATDAFSGSLYHDGDRAIVEAVTRIAGERGVSRAQVALAWLLQQPTVTAP
                     IVGASKPGHLQDAVAAVELRLTDGELEELERPYGPHPVAGH*"
     CDS             complement(9862..10397)
                     /protein_domains="PF02441"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522646"
                     /pseudo=False
                     /translation="MIEQAARKPFLYVVVCAAGVAADLGKLITAAQERQWEVGVIATPV
                     AMNGFFDTTAVEARTGRRIRSAWRTPGEPRPFPAPDAVVVAPATFNTVNKWAAGIADTL
                     ALGTLCEAAGLGVPIAVLPCVADALAAHPAYRDSLERLRGMGVRFGEPYAGEPGEDGGR
                     PDFGWERALELVERR*"
     CDS             complement(10648..10844)
                     /protein_domains="PF13459"
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_2522647"
                     /pseudo=False
                     /translation="MHIDIDKDLCIGAGQCALTAPDVFTQDDEGYSMLLPGGEDSGSPL
                     LREAARACPVGAITVSETVS*"
     CDS             complement(10860..12055)
                     /protein_domains="PF00067"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522648"
                     /pseudo=False
                     /translation="MTETTAPVAFPQSRTCPYHPPAAYDALRTERPLTRITLFDGREAW
                     LVSGHATARALLADPRLSSNRDRPGFPAPTQRFAGIRNRRTALLGVDDPEHRVQRRMVV
                     GDFTLKRAVELRPRIQQIVDERLDAMIAQGPPADLVSAFALPLPSMVICALLGVPYTDH
                     DFFETQSRRLLRGPETADVLDARDRLETYFGELIDRKQRDAGTGLLDDLVHRQLREGDL
                     DREGLIAMALILLVAGHETTANMISLGTFTLLQHPERLAELRADPRLLPAAVEELMRLL
                     SIADGMLRLAVEDIEVAGTTIRKGEGVVFATSVINRDETVYPDPDTLDWSRPARHHVAF
                     GFGIHQCLGQNLARAELEIALHSLFARLPGLRLAAPADEIPFKPGDTVQGMLELPVTW*
                     "
     CDS             12398..13029
                     /protein_domains="PF01810"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522649"
                     /pseudo=False
                     /translation="MTAALVAGLLAGYGIAVPVGAVGTYLVSLTARTTLRTGVCAALGV
                     ATADGLYALAATLGGTALASALRPVLGPLRWVCVLVLLALAARGAVTAVREYRGHRLAT
                     RSAPAPPSPVRAYLGLLGITLLNPTTVIYFAALVLGSRATGPAGPVEQGVFVAAALAAS
                     ASWQVLLAGSGALLGRALTGRRGRLATAWVASGVMTALAVRMALAPG*"
     CDS             13136..13584
                     /protein_domains="PF04075"
                     /protein_domains="TIGR00026"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522650"
                     /pseudo=False
                     /translation="MPLEGEYEPSPTQWVRKQVELYESSGGTEGTTLQGSKMPVVVLTS
                     RGARSGKLRKTPVMRVEHEGRYAAVASLGGSPKHPVWYFNLRADPHVELQDGPVKRDMT
                     AREVTGEEKAAWWERAVAAYPAYADYQKKTDRDIPVFVLEPAEEG*"
     CDS             complement(13673..14592)
                     /protein_domains="PF01545"
                     /protein_domains="TIGR01297"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522651"
                     /pseudo=False
                     /translation="VLVALAANLVIAVAKAIGGLVAGSPALLSEAAHSVADSLNEVFLL
                     AALRRSRRPADRRHPFGYGKERFFWSLLAAVGIFVMGGCFSFFQGFEALTSETEEELSG
                     YVAGLIVLGVALLAEGASLVRALYQVRRQGGASAGLRDPALRTVVAEDGTAVLGVTLAM
                     VGMALHMVTGQAVWEASASIAIGALLVYVAFRLGREARDQLIGEAADPESSGRICALLR
                     AQPEIDSVEALFTMKTGLDTALVAARVDLVPGLDSERVEEVAVRIKRSIARTVPEADQI
                     FLDVTDRPAREAAESPAATGERGGA*"
     CDS             14734..15758
                     /protein_domains="PF13410"
                     /protein_domains="PF13409"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522652"
                     /pseudo=False
                     /translation="MSRDDGDDGNTGYGRRAFKRSKAHFADRITADGRDGWPVEAGRYR
                     LVVSRACPWASRSLVSRRLLGLEDALSLAVADPIQDDRSWRFTLDEDGRDPVLGIRYLS
                     EAYDRRESDYPGGVSVPAIVEVSSGRLVTNDYQQLTLDLATEWTALHREGAPDLYPAAL
                     RDEIDEVMADVYEDVNNGVYRAGFATGQEEYEAACAGVFRRLELLAGRLERQRYLVGDT
                     ITEADIRLFTTLVRFDAVYHGHFKCNRWKLTENRVLWGYIRDLYQTPGFGDTVDFDHIK
                     RHYYQVHTGINPTRIVPLGPDLAGWLTPHHREELGGRPFGDGTPPGPVRPEERIPAAHT
                     P*"
     CDS             15794..16089
                     /protein_domains="PF14019"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_2522653"
                     /pseudo=False
                     /translation="VAKKKKMSLAYQPLGFVLGWSGGWLAGLAFRKTWMAIRHEEDAPD
                     ALDKDRGWGEVLLAAAIQGAIFAVVRSAVDRAGAKAIERSTGTWPVGEKGGRD*"
ORIGIN
        1 atgagtccgg acgagccgtt cgacgatggc gtggcagccc gcgccgtcat cgccgtcgac
       61 ggcacgctca ccgagtggag cgagggtgcg cgccgtctgc tggggcacac ggccgacgag
      121 gtcgtgggcc gcccggccgc cgcgctgctg gccgacggcg ccgacccgcc gtccgtgcgg
      181 gacggctctc gctggagcgg cacactcacc ctgcgtcacc gcgacgggca cccggtctcc
      241 ctctgggtgc tcgcccaccg caggcctccc gacggagccg aggcgaccga ttggctcgcg
      301 gtgtccccgc cggaggccgc cgaccagggg cttggcgacg acccgctggt gcgcctggcc
      361 ctgacgcagt cgccctgcgc cacgatgatc ttcgacgagc ggctgcggct gcgcggcctc
      421 aacgacgcca tggcggacct cctggggctg cccgccgcgc ggatgctggg gctgaagccc
      481 accgacatcg gcagccgacc gcagaacgcc gagctcgagg agtatctgcg cagggtgctg
      541 agcaccggcc ggcggcagga gatgcagacg tacatgaagg cgaccggcga gagccggggg
      601 gcccacgcct ggctggccag gatggccccg ctcaccgacg gcaccggccg ggtgcgcggc
      661 gtgtgcgtga cggcccacga cttctccgac cagtaccggt cacgggagcg gctgctgctg
      721 gtcaacgagg cgagcgtgcg catcggcacg accctcgacg tcacccgtac ggcgcaggag
      781 ctggcggacg tgtgcgtgcc ggcgctcgcc gacttcgtca gcgtggacct cctcgacccc
      841 cgggaccacg gcggcgagtc cgccgggccg ccgattccgc cactgagcct gcgccggtcc
      901 gcccaccagt ccgtcaacaa gggcagcccc gaggccgtcg ccaaacccgg acaggtggac
      961 gtctacccgg agaactcccc gcaggccgcc tccctggtgg ccgggcacac cgtcgtggcc
     1021 tcgggcgcgt cgggcgacct cgagcgctgg ctcgcctggg acccggtgcg cttccagcgg
     1081 atacaggagt acggcatcca ctccacgatg tccgtgcccc tgcaggcccg gggcacgacc
     1141 ctgggcgtgg cggtcttcac ccgcttccgc cgccccgagc cgttcacccc cgacgacgtg
     1201 ctgctggccg aggaggtcac ggcccgggcc gccgtctgca tcgacaacgc gcgccgctac
     1261 tcccgcgagc gcgagacgac cctcaccctg cagcgcagcc tgctgccccg cacccttccg
     1321 cacacggcgg cggtggaggc cgcgtcccgc tacctgccgg ccacgcgctc cggcgtgggc
     1381 ggtgactggt tcgacgtgat cccgctgtcg gggatgcggg tcgccatgat cgtcggcgac
     1441 gtcgtcggtc acggcatcca ggcctcggcc accatgggcc ggctgcgcac cgccgtccgt
     1501 acgctcgccg acatcgacct ggcgcccgac gaactgctca cgcacctcga cgacctcgtc
     1561 gtacggctgt cggaggagtc cggcggggac gacggcaccg gggaggtggg cgcgacctgc
     1621 ctgtacgcgg tgtacgaccc ggtctcacgg cgctgcaccc tggcccgggc cgggcatccc
     1681 ctgcccctgc tggtgccgcc gggcggcccg gcgcgccagc tcgacctgcc ctcggggccc
     1741 ccgctgggtg tcggggggct gccgttcgag gcggccgagg tggagctgcg cgagggcagc
     1801 atcctggtct tccacacgga cggactgctc gtgagccgtg agcgggacgt cgacaccagc
     1861 ggccggatgc tccgcgaggc gctgtcggct tcctccggct ccctggacga gacctgcgac
     1921 cgcgtgctga acacactcct ccccccgggc ggctccagcg acgacgtggc cctgctgctg
     1981 gcccgcaccc gcggcctgcc gtccgcccag gtcgccacct gggacatccc ggccgacccg
     2041 gcactggtgg cccccatccg caagcaggtc gtcgaccagc tggaacgctg ggggctgctc
     2101 gaagccacgt tcaccgccga gctggtggtg agcgagctgg tcaccaacgc catccgctac
     2161 ggcgccccgc ccatccggct ccggctgatc catgacgcgg ccacgctgat ctgcgaggtg
     2221 tccgacacca accacacggc accgcacctg cgccgggcga agacctggga cgagggcggc
     2281 cgcggcctgc tcctcgtcgc ccagctcacc cagcggtggg gcagcaggca caccggcgag
     2341 ggcaagacga tctgggcgga gctggccctg ctcggcgacg agctctgagc acccgctccg
     2401 caccggcagg cgggcggggg ccgccccgga caggacgtga cagggcccct gaggttctct
     2461 taccagcgcc tggtttcatg ggcgggcacg accagaccac gctccggagg acaccgccct
     2521 gaacgccccg ctcgccgaag tcctgtccgt gacgctgctg gccactgtgc tgatctgggc
     2581 cgtcgcccgc cccaagggcc tgcccgaggc cgtgctggcc gtgcccgccg ccggtctcgc
     2641 catcgccctc ggagtgatct cgcccgagca cgccggggag gagatccagc ggctcgggcc
     2701 cgtggtcggc ttcctcgccg ccgtgctggt gctcgcccac ttctgcgacg tggaagggct
     2761 cttcaccgcc tgcggggcgt ggatggcccg ctgggcggcg gggcgcccca cacggctgct
     2821 gaccgcggtg ttcgcgctgg cctccgtcat cacggccgta ctcagtctgg acgccacggt
     2881 cgtcctgctg accccggtgg tgctcgccac cgccacccgc atgggcgtgc aggcacgacc
     2941 gcacctgtac gcctgcgccc atctgtcgaa caccgcctcg ctgctgctgc cggtctccaa
     3001 cctgaccaat ctgctggcct tcaccgcgag cggactgagc ttcacccgct tcgcggcctt
     3061 gatggcgctg ccgtggctgg tcgccatcgc cgccgagtac ctggtgttcc gccgtttctt
     3121 cgacgacgag ctcgcggcgc ccgtaccctc ccccgactcc gacccccgtc ccgaacctct
     3181 cccgctgttc gcccttgtca ccgtcggctg cacactcgcc gggttcgtcg tcgcctccgc
     3241 cgtggggatc gcgccggcct gggccgcgac ggccggtgcg ctggtgctgg ccgggcgggc
     3301 gctggtgcgg cgccgggcca cgccgctcgc ggtggtgcgc tcggcgcaac cggcgttcct
     3361 ggcgttcgtg ctcgcactcg gcgtcgtcgt gcgcgcggtc gtcgaccacg ggctcgccga
     3421 cgcgctgcgg cacgtcctgc ccgacggttc gggactggtc accctgctgg gcgtggcggc
     3481 gctggccgcg gtcctggcga acctcatcaa caacctgccc gcggtgctgg tgctgctgcc
     3541 cctgaccgcc gggtccggtc ccggtgccgt gctggcggtg ctgctcggtg tcaacatcgg
     3601 ccccaacctg acctacgccg gatcgctggc gaccctgctg tggcggcgga tcgtccagca
     3661 gggcgggcac cgggtgggtc tcggcgagtt cacacggctc gggctgctcg ccgtaccggc
     3721 cgcgctggtg tcggccgtgg ccgccctgtg gctgtcactg gccgtcgtcg gcgtctgagc
     3781 ccgccgcccg gtcagcggcg gccgtctccg ccgcggccgt agccgtggcc ggggtaaccc
     3841 tggtcagggt tgccgtagcg gccgtcggag tcgcagtggt agcggtagca ggacgggtct
     3901 gtggcggccg ggctgctcgg cgtctgctcc ggcgccgggg aggccgggga cggagtcggt
     3961 gtgggcgcgg gtgtcctcga ccgtgtggga ccgggggacg gtgcgggggc ggtgcgggtc
     4021 gccggaacgt tggcgttcca gttgacggcc tgcacctgga gatcggccct ggaggtgtcg
     4081 atcacccagc gctggacctc gtcgtccgtc cgggccttga ggaccagggc gccggagccg
     4141 tcggtcgcgg cgggggcaag ggcgaggtcc tggtcccagc ggggcaccag ggcgccctgc
     4201 agggtgaagt cgtagcggat gttcttcggg tccgggcggg aggcgcccgt gcagggagcc
     4261 agccggaccg agtaaccgag ctgcgagtcc aggcacaggt ccggcgcggc gccgttgcgc
     4321 agcagtccgt cggtctcgta cgtccactgc tgggcggctt ccgcggagca ggtcgtcagc
     4381 tcggcctccg cgccctcgac ggccttgtcg ccgtcgacgc cgacgcacag gtccgaggcg
     4441 acgttgtgca gccggccgtg gagggcgccc tggcgggcgt cacccgcgcc ggtccgggac
     4501 gggtcggtgt tcctctcacc ggcgtcgggg tcgggtgcct ccccggctgc tcgatcggcg
     4561 ccggccgggg cgctgtcacc ggagtcgccg gtggaccaca ggaccagcgg cagaaccacg
     4621 aggccgctga cggtcaggat gcccacggtg agattgcgcc gccgtgcgac acggcgggcg
     4681 gccctccggc cggacctggc cgaccttcgg gcggcgcttc gggagccttc gctccggtgg
     4741 gccggggcca cggtggcgat cggcagggag cggcccacgc cggccgcagc ctcggcggtg
     4801 cccccggcag ggtcgcggct ctcggccccg gcagggggcg gcggcgcggt cgccgggccg
     4861 cccggctcgg tgaacgactc ccccaccgcg ccggcgaggg cgaccggatc ggggaagacc
     4921 tcacgcccgt cgccgggctg tcctcggaag gcctcccgtg ccgcacgcgg cggcgcaggg
     4981 aacgaccgac cagccgggcc ggccaagccc tcgcgcgtcg caccggccgg atccgcaagg
     5041 ccctcgcgcg ccgcgcggga acccgacaag ccctcgcgcg ccgcacgggc cagatccgtc
     5101 aggctcctgc gtgccgcacc ggccgtattc gtcccgcccc tgcgtgccgc acgggccgga
     5161 cctgtagacg ccttgcgcgc cgcacgcggc gaggccggga agccttcgcg cgcctcaccg
     5221 gccgactccg cgagcccctc gccacccgcc ggtcccgcaa agccctcgcg cgccgcatcc
     5281 gcaggccccg gggaaacctc gcctcccgca cccctcggtc ccgcaaagcc ctcgcgtgcc
     5341 gcacggaccg gattcgtcac acccttgcgt gccgcacggg ccggccccgg aaaggccctg
     5401 cgtgccgcac gcggcgaggc cgggaagcca tcgcgcacct caccggccgg ctccgcgagc
     5461 ccctcgccac tcgccggtcc cgcaaagccc tcgcgcgccg cacgggccgg gtccggcatg
     5521 atctcgtacg ccatgccggc gggttccggg aagacctcgc gggccagggc cacggggtcc
     5581 gggaacagct cgcgtgccgc gccggccagg gccccggcgg ccgcaccggc ctccgccccg
     5641 ggccgtcggc gctccgcggc ccgcccaccc ccggtgtggt ctgccgcctc gccgatccgg
     5701 ctctccgcgt agccccgccc gccccagccc agcacccctt ccgacagggc gacgccgagg
     5761 gcgtggttga actggtcgag ctggtccgcg gcaacgctgc agtgcccgca gccctctata
     5821 tgcgcgcgta gatcggggtc gatgtcgagc ccccctcgcc ggtacgtcac gtcgagcagc
     5881 cgcagatagc gccggcactc ctcgtcgggg gcgagttcac ggtggagctg caggcattcc
     5941 tcgcgcagcc ggtcgcgggc ccggtccagt tcgacgcgcg cgccctcctc gtccaggccg
     6001 agcagcgcgg ccggagacga cagcggttcg gcctcgacct cgacgtgcca cagcaggcag
     6061 cgggcggact ggggcagccg ctggaaggcg ccggacagca ggcgccggtg tcgcgacggc
     6121 agcagtcggg aggccggccg ctccccgtcg ccggtgtcgg ccagcagcgc cgggtggagc
     6181 atgtcgcttc ggtggtcgcc cgcccactcg gccgcgatcc gccgcacggt gaggagcaga
     6241 tgggaccgcc acgcggaggt cggtccgttc tgccggaggg tctcgccgaa gagccgggtg
     6301 aacgccgcgg tggtgagcat gcccgcggag cgcggaccgt cggtgcacag ccgggcgtag
     6361 gcgaaggccg cctcccagtg ccggtccagc agttcgccga cggggtggag tgcgggcgtc
     6421 gcccccgtcc acttcctgag ctccgcgctc agttgctcgt ccgtcgcacc gaacccgcgg
     6481 gccgaggccg gggaattcga cgggcctgcg tctttcacgg ctgcattcct ctcaaggaca
     6541 tgcggaacaa agtccgtacc aaggggtatg ccggccggcg gccgcgcgca tacgaaagaa
     6601 aggcgtgtgg gggcacgccg tcagggcaca cctttacaca ggtcagggac ggggaacaag
     6661 ggatcacgcg gtttcgcgca ttgcgtggac gcgcagcggc ttttgacaag aagtcagcca
     6721 gtggcgcgaa aggcatttcc gtgccgtccg cccctttcta tacgactgac attttcccgc
     6781 cccgccggtc gcccggaaac cattgagtca ccccccgagc agcagctcac gcggtgggcg
     6841 gcgttccgca ccggtctttc gatgtctgcg gcggaaccaa tagcggtgct cagccggccg
     6901 caccgccgtg tgtcgcccgg tacgccccgg gcggtgcccc gtagcgctcg cgaaaggcgc
     6961 ggttgaagtg gaacgggctg acgaaacccg aggccgtcgc gacgcgttcc acgggcaggt
     7021 cggtgctctc cagcagccgg gcggcatggc gcagccgtgc ctcgcgcagg gcccgcatgg
     7081 gcgagcggcc gagctgactg ctgaacagat gggcgaagcg ggacggcgac agcgcgacgc
     7141 cctcggcgag ggagcggacg gtgtgcgggg cgcccgggtc ggcgtcgatc agctcctgcg
     7201 cgcgacggac ccgtgcgtcg aggccgggcc ggggagccgg cggccgggcg gtggtgagga
     7261 ggacgatctc ctccagtgcg cacagggcca gttcgcgggc ggcgctgccg tgggccacgg
     7321 cgacctgccc gtccgggggc gccccgtcgg gcagggcttc ggtgccggtc cagcgggcgt
     7381 cggtgtgcat ccgccggaac gccgccccga cgcggccgtg cacgccggcc gggacggagg
     7441 cgatcaggta catcccgtga ccggcgtcgt acggccgcag ccacgcggcc caggacgggc
     7501 gggcctggca gtgcgcccac cagaaccgcc agtgcccggc gccggactcg actccgtacc
     7561 cgtgcgggac gcccggggcg agtacgacca gtgcgcccgc cccggccgag gtgttcgcac
     7621 cgccctgcca caggcgtccc cggcctgcgg tggtccaggt gaagagccag ctcgcggacc
     7681 cgtgcggccg gtggacgccg tacccgtgcg gctggtcgaa gtggccgacc acgaccagtc
     7741 cgggcggcgg ggcgggatct ccggtgttcc ccgtgctccc ggtcttccct gtctgcccgg
     7801 tgtggctcgc ctcgacagtc tcgggcaatc cgtcagcacg cacgggcatc ctcctcgatg
     7861 gcccggaggc ctagcgtctt gcgccgagga cacccgagcg aggagtgcgt tcatgacagt
     7921 cacgggcaac ggcgccgtcg gcgcctccat cctggaccgc gaagagctcc ggcggtaccg
     7981 ggaggagttc gatggggtcg gtttcacggt ggtacggggg cttttcgcgg ccggcgagat
     8041 cgaccggctg tgcggggagt tcgcggcact gcgggcggcc ggtccggtgc ccgggcattt
     8101 cgagccgcgt gcggtggacg ggccgggcgc ggaccccctg cacgtgtggc cccgggtgat
     8161 gcacccgcac gagatcaacg gcctcgcgcg cgaggtcctg ctcgacgccc ggctgcggac
     8221 ggttctggag gcgctgctcg gggaggaggt gctggccgcg cagagcatgt tctacttcaa
     8281 gccgccgggc gcccgggggc aggcgctgca ccaggacaac ttctacctca gggtggagcc
     8341 cggcacgtgt gtggcggcct ggacggcctg tgacgtgatc gaccgggaga acggggggct
     8401 ggaggtcgtg ccgggcacgc acctgatgga cctgttctgc ccggagcagg ccgacgcgga
     8461 cgtgtccttc gcccgggagt acgttccgcc gccggccggg ctggcgccgg tgccggtgga
     8521 catggcgccg ggcgacgtcc tgttcttcaa cggcagcctg gtgcacgggt cgcagccgaa
     8581 ccggacggcg gaccggttcc ggcggtcgtt catcgggcac tacgtgggcc ggtcgacgga
     8641 gcggatcggg cggttctacc ggacgctggc gatgagcggc gcgcgggtgg agctcgcgga
     8701 gagcgagggg gcgggcccct gcggaacgga gttcgcgccg caggggcctc actgaccttc
     8761 gaggggtggg ttcagtggcc ggcgaccggg tgggggccgt aggggcgctc gagctcctcc
     8821 agttccccgt cggtcagccg gagttccacg gcggccaccg cgtcctgaag gtgcccgggc
     8881 ttggaggcgc cgacgatcgg tgcggtcacc gtgggctgct ggagcagcca ggcgagggcg
     8941 acctgcgcgc gggagacgcc ccgttcgccg gcgatgcggg tgaccgcctc cacgatggcg
     9001 cggtcgccgt cgtggtacag gctgccgctg aaggcgtccg tggctccgcg ccgggtcgtg
     9061 gtgtcccagt cccgggtgag acggccgcgg gcgagcgggc tccagggcag cacccccaca
     9121 ccctggtccg cgcacagggg gagcatctcg cgctcctcct cgcggtagat caggttgtag
     9181 tggttctgca tggagacgaa gcgtgtccag ccgttcagac gggcggtgta ctgggccttg
     9241 gagaactgcc aggcgtacat cgaactggct ccgatgtagc ggaccttgcc ggccttgacg
     9301 acgtcgtgca gggcttccat cgtctcctcg accggggtgt gcgggtcgaa gcggtggatc
     9361 tgatagaggt cgacgtagtc ggtgccgagg cgggtgaggc tgtggtcgag ctcggtcatg
     9421 atggccttgc gggagaggcc gccgccgttc ggtccggggc gcatccggcc gtgcaccttc
     9481 gtcgcgagga cgatctcgtc acggcgggcg aaatcgcgca gggcccggcc gacgatctcc
     9541 tcgctggtgc cgtcggagta gacgttggcc gtgtcgaaga aggtgatgcc cgcctcgacg
     9601 gcctgccgga tcagcgggcg cgaggcctcc tcgtcgaggg tccactcgtg ggtgccgcgg
     9661 tcgggcagcc cgtaggtcat gcaccccagg ctgatccgcg agacgtccag gcccgtcgaa
     9721 ccgagcttca cgtactgcat ggttggctgc tcctgctttc ggggggattg cacggggagc
     9781 gtacgtgttc gtgtgcgctc gaaggcaagg ccgggcgggg ctcctgacgg gccgtccgcg
     9841 cgtggccccg ggcctgccgg tcagcggcgt tcgaccagct ccagggcccg ctcccagccg
     9901 aagtccggcc gtccaccgtc ctcccccggc tctcccgcgt acggctcacc gaaccgcacg
     9961 cccatccctc gcagccgttc gaggctgtcc cggtaggcgg ggtgggcggc cagagcgtcc
    10021 gccacgcacg gcaggacggc gatcggcacc ccgagccccg cggcctcgca cagggtgccc
    10081 agagcgaggg tgtcggcgat gccggccgcc cacttgttga cggtgttgaa ggtggcgggg
    10141 gcgaccacca cggcatcggg cgccgggaag gggcgcggct cgccgggcgt gcgccaggcg
    10201 gagcgtatgc ggcgacccgt ccgggcctcg acggcggtgg tgtcgaagaa gccgttcatg
    10261 gcgacgggcg tcgcgatgac tcccacctcc cactgccgtt cctgcgcggc ggtgatcagc
    10321 ttcccgaggt ccgcggcgac gccggcggcg cagacgacga cgtagaggaa gggcttgcgg
    10381 gcggcctgtt cgatcatccc ggaaccctag cgactgtccc gggctcaccg gaccgggaag
    10441 gtgccggcgc cttccggctc cggccggacc gcgctcgtcg aactcctcct ccctgtctgc
    10501 agctgacaac gatcgttccc cccgaacggc gcgacacccg tcggcgcgcg ccaccgacgg
    10561 cgggcctttc caggagccgc cgcgcccgag tccggggcgc gcgaggcggc ccggcggctc
    10621 ctgagtgccg gggtggatcc gggtggtcag ctcaccgtct cggacacggt gatggcgccg
    10681 accgggcagg cgcgggccgc ctcccgcagc agcggactgc cactgtcctc gccgcccggc
    10741 agcagcatgc tgtagccctc gtcgtcctgg gtgaacacgt ccggggcggt cagggcgcac
    10801 tgccccgcgc cgatgcagag gtccttgtcg atgtcgatgt gcatgggtgc gcgggccctc
    10861 accaggtcac ggggagttcc agcatcccct ggaccgtgtc gcccggcttg aacgggatct
    10921 catcggccgg ggcggccagg cgcagaccgg gcagcctagc gaagaggctg tgcagggcga
    10981 tctccagctc ggcgcgggcg aggttctggc cgaggcactg gtggatgccg aagccgaacg
    11041 cgacgtgatg acgggccggg cggctccagt ccagcgtgtc cggatcgggg tagaccgtct
    11101 cgtcgcggtt gatgacggag gtcgcgaaga ccacgccctc acccttgcga atggtcgtcc
    11161 ccgccacctc gatgtcctcg acggccaggc gcagcatgcc gtccgcgatc gacagcagcc
    11221 tcatcagctc ctcgaccgcg gcaggcagca gccgcgggtc cgcgcgcagc tcggcgagcc
    11281 gctcggggtg ctggagcagg gtgaacgtgc cgagcgagat catgttcgcg gtcgtctcgt
    11341 ggcccgcgac cagcaggatg agggccatgg cgatcagacc ctcgcggtcg aggtcgccct
    11401 cgcgcagctg ccggtggacc aggtcgtcca gcaggccggt acccgcatcc cgctgcttgc
    11461 ggtcgatcag ttcgccgaag tacgtctcca gccggtcacg ggcgtcgagg acgtcggcgg
    11521 tctccgggcc gcgcagcagc cgccgggact gggtctcgaa gaagtcgtgg tcggtgtagg
    11581 ggacgccgag cagggcgcag atcaccatgg acggcagggg cagcgcgaaa gcgctcacca
    11641 ggtccgcggg cggcccctgg gcgatcatcg cgtcgagccg ttcgtccacg atctgctgga
    11701 tgcgtggccg gagttcgacg gcccgcttga gggtgaagtc cccgacgacc atccgccgct
    11761 ggacgcggtg ctcggggtcg tcgacgccca gcagggccgt tctgcggttg cggatcccgg
    11821 cgaagcgctg ggtgggggcg gggaagccgg ggcggtcgcg gttggacgac aggcgcgggt
    11881 cggccagcag ggcgcgggcg gtggcgtgcc cgctcacgag ccaggcctcg cggccgtcga
    11941 agagggtgat ccgggtcagg ggccgttcgg tgcgcagcgc gtcgtaggcg gcgggcgggt
    12001 ggtaggggca ggtccggctc tgggggaagg cgacgggtgc ggtcgtttcc gtcatttaga
    12061 cctcgcagac gagtagtgcg tcgtgccgcc cgccattaga tgcccaaggc atctaatggt
    12121 gcgacgcgaa gttcggccag atcaccggcg ccggcaactt ggccggggaa cgtcgtcctc
    12181 gcgttcgaac gacggcggcg ggaggcgtgc ggtgcccggg cccgcgccag agcccgcgcg
    12241 cgagggcccg cgcgaaaacc ggttgtcggc acggccgggc aggccgcagg atccggccat
    12301 gcctacgttc actgttctcc tgccgctgcc cgccgcctct gccgcgcgcc gacagcagca
    12361 gtccggccgc cgcggaggac cgacaccggc ccggtcatga cggccgcgct cgtcgcgggg
    12421 ctgctcgccg ggtacggcat cgccgtaccg gtgggcgccg tcgggaccta cctcgtctcc
    12481 ctcaccgccc ggaccacctt gcgtaccggc gtctgcgccg cgctgggcgt cgccaccgcc
    12541 gacggtctct acgccctcgc ggccaccctc ggaggaacgg ccctggcctc cgcgctgcgt
    12601 cccgtgctcg ggccgctgcg gtgggtctgt gtgctggtcc tgctcgcgct ggcggcacgg
    12661 ggcgcggtca ccgcggtgcg cgagtaccgc ggccaccggc tcgccacccg gtcggccccg
    12721 gctcccccga gcccggtccg ggcctatctg ggcctgctgg gcatcacgct gctgaacccc
    12781 accaccgtca tctacttcgc cgcgctcgtg ctcggttccc gggccacggg accggccggt
    12841 cccgtggaac agggcgtgtt cgtcgcggcc gccctcgccg cctccgcgag ctggcaggtg
    12901 ctgctcgccg ggagcggggc cctgctgggc cgggcgctga ccggccgccg ggggcggctg
    12961 gcgacggcat gggtggcgag cggggtgatg acggcgctgg cggtgcggat ggcgctcgcg
    13021 ccgggatgag atgcgcatcc gggcggatgt ccgcgggtgc ggatgatttc cccggggcac
    13081 ggttgttgac agcagacggc gacaagccgc aaacgcgacg atgggacgga tgtcatgccg
    13141 ctcgaaggcg aatacgaacc cagcccgacg cagtgggtgc gcaagcaggt ggagctgtac
    13201 gagagctccg gcggtacgga ggggacgacc ctgcagggct cgaagatgcc ggtcgtcgtc
    13261 ctgacctcgc ggggcgccag gagcgggaaa ctgcgcaaga caccggtgat gcgggtggaa
    13321 cacgaggggc gctacgccgc ggtggcctcc ctcggcgggt cgcccaagca ccccgtgtgg
    13381 tacttcaacc tgcgggccga cccgcacgtg gagctccagg acggtccggt gaagcgggac
    13441 atgaccgccc gtgaggtcac gggtgaggag aaggcggcct ggtgggaacg agccgtcgcg
    13501 gcgtatccgg cgtacgccga ctaccagaag aagacggacc gggacattcc ggtcttcgtc
    13561 ctggagccgg ccgaagaggg ctgacagcgg gccggctgcc cggtgcgggc agccggcgga
    13621 aaaatcttcc gccccgtgag tgtgaacccg ccgcgccggg gcacgcgagg ttcaggcccc
    13681 gccgcgctcc cccgtcgcgg cggggctttc cgctgcctcg cgggcgggac ggtcggtcac
    13741 gtcgaggaag atctggtcgg cctcgggcac cgtccgggcg atggaccgct tgatgcgcac
    13801 ggcgacctcc tcgacacgct cgctgtccag gccgggcacc aggtcgaccc gggcggccac
    13861 cagggccgtg tcgagtccgg tcttcatcgt gaacagcgct tccacgctgt cgatctcggg
    13921 ctgtgcgcgc agcagcgcgc atatgcgccc gctggactcg ggatcggccg cctcgccgat
    13981 cagctggtcg cgggcttcgc ggcccagccg gaaggccacg tagaccagca gcgccccgat
    14041 cgcgatcgag gcggacgcct cccacaccgc ctgaccggtg accatgtgca gagccatgcc
    14101 caccatggcc agggtgacgc cgagcacggc ggtgccgtcc tcggcgacga ccgtccgcag
    14161 agccgggtcg cgcagcccgg cgctcgcgcc gccctgccgt cgcacctggt agagcgcccg
    14221 taccagcgaa gcgccttccg ccaggagggc gacacccaac acgatcaggc ccgccacata
    14281 accgctgagc tcctcctccg tctcgctcgt cagagcctcg aagccctgga agaacgagaa
    14341 gcagccgccc atgacgaaga tcccgacggc cgcgaggagc gaccagaaga accgctcctt
    14401 gccgtagccg aagggatgac gccggtcggc ggggcgtcgg ctgcggcgca gtgccgcgag
    14461 caggaacacc tcgttcaggc tgtcggccac cgagtgggcc gcttcggaca gcagggccgg
    14521 tgaccccgca accaggccgc cgatggcctt ggccaccgcg atcaccagat tggccgcgag
    14581 cgccaccagc acggtgacgc gtgtcttgtg atcacttcct tcatcagtca cctccgccga
    14641 ttgccccggt cgggggtact cacaccgtgc cgtccacgga aaacggggaa cgcgttcacc
    14701 agggcccacg caaggcagag gaggtcaccc ccatgagccg cgacgacggc gacgacggca
    14761 acaccggcta cggaaggagg gcgttcaaac ggtccaaggc acacttcgcg gaccggatca
    14821 ccgcggacgg ccgggacggc tggccggtgg aggccggccg ctaccgtctg gtcgtcagcc
    14881 gtgcctgccc gtgggcgagc cggtccctgg tctcccggcg gctgctcggc ctggaggacg
    14941 ccctgtccct ggccgtcgcc gacccgatcc aggacgaccg cagttggcgc ttcacgctgg
    15001 acgaggacgg ccgcgacccg gttctcggca tccgctacct cagcgaggcc tacgaccgcc
    15061 gggagagcga ctacccgggc ggtgtcagcg tgccggcgat cgtggaggtg tccagcggcc
    15121 ggctggtgac caacgactac cagcagctca ccctcgacct cgcgaccgag tggacggccc
    15181 tgcaccggga gggcgcgccc gacctgtacc cggccgcgct gcgcgacgag atcgacgagg
    15241 tcatggcgga cgtctacgag gacgtcaaca acggcgtcta ccgggcgggc ttcgccaccg
    15301 ggcaggagga gtacgaggcc gcctgcgccg gggtcttccg gcggctggag ctgctcgcgg
    15361 ggcggctgga gcggcagcgg tacctcgtcg gcgacacgat caccgaggcg gacatccggt
    15421 tgttcaccac actggtccgc ttcgacgcgg tctaccacgg ccacttcaag tgcaaccgct
    15481 ggaagctgac ggagaaccgg gtgctgtggg gttacatccg cgacctgtac cagacgccgg
    15541 gattcggcga caccgtcgac ttcgaccaca tcaagcgtca ctactaccag gtgcacacgg
    15601 gcatcaatcc gacccgcatc gtgccgctgg gccctgacct ggccggctgg ctgaccccgc
    15661 atcaccgcga ggagctgggc ggccggccgt tcggtgacgg cacaccgccc gggcccgtcc
    15721 gccccgagga gcggatcccg gcggcgcaca ctccctgacc accctcaccc cctcagctac
    15781 caaggagttc ccgtggcaaa gaagaagaag atgtccctcg cgtaccagcc gctcggattc
    15841 gtgctcggct ggtcgggcgg ctggctggca gggctcgcct tccgcaagac gtggatggcg
    15901 atccggcacg aggaggacgc gcccgacgcg ctggacaagg accgcggctg gggcgaggtc
    15961 ctgctggccg ccgcgatcca gggcgccatc ttcgcggtgg tgcgcagcgc cgtggaccgc
    16021 gcgggcgcca aggccatcga gcgttcgacc ggcacgtggc cggtcggcga gaagggcggc
    16081 cgggactga
//
