LOCUS       reptomyces_RBGC_360170 16565 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_360170
VERSION     Streptomyces_RBGC_360170
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_002224125.1
  ORGANISM  GCF_002224125.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1941
                     /protein_domains="PF09382"
                     /protein_domains="PF00570"
                     /protein_domains="PF00271"
                     /protein_domains="PF00270"
                     /protein_domains="PF16124"
                     /protein_domains="TIGR01389"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704349"
                     /pseudo=False
                     /translation="VPLPEIDPLTNGDISDSPPSSPDTIEPDTGDPDPGDTSDALRVLR
                     RVFGYDAFRGDQQEIIDHVVAGGDALVLMPTGGGKSLCYQIPALVRRGVGVVVSPLIAL
                     MQDQVDALRALGVRAGFLNSTQDLDERRLVEAEFLAGELDLLYLAPERLRVESTLSLLG
                     RGSISLFAIDEAHCVAQWGHDFRPDYLALSELHERWPDVPRIALTATATEATHTEIASR
                     LKLQDARHFVASFDRPNIQYRIAPKNDPKRQLLELLRTEHQGDAGIVYCLSRASVEKTA
                     EFLVKNGIEALPYHAGLDARTRAENQARFLREDGLVVVATIAFGMGIDKPDVRFVAHLD
                     LPKSVEGYYQETGRAGRDGLPSTAWLAYGLQDVVQQRKMIDGSEGDAAHRRRLGSHLDA
                     MLALCETVECRRVGLLAYFGQRSTACGNCDTCLTPAESWDGTVPAQKLLSTVVRLKRER
                     NQKFGAGQVIDILLGKKTAKVIQFDHDALSVFGIGTELREAEWRGVVRQLLAQGLIAVE
                     GDYGTLVLSESSGEVLGGQRQVMLRREPERAPRAAKSSSSSAKSGRAAAPVDLPPEAVP
                     LFERLRAWRGATAKEQGVPAYVIFHDATLRQIATLSPGTLAELGAVSGVGENKLAKYGE
                     QILETVAAAEE*"
     CDS             complement(1995..3961)
                     /protein_domains="PF00183"
                     /protein_domains="PF02518"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704350"
                     /pseudo=False
                     /translation="VNTKAETFEFQVEARQLLQLMIHSIYSNKDVFLRELISNASDALD
                     KLRLESLRGTDLHADTSDLHIELEVDQERRTLTVRDNGIGMSHDDVVQLIGTIAKSGTA
                     EFLRELKDSKEESKDAAASQDLIGQFGVGFYSGFMVADQVTLVTRHATESQGTRWESTG
                     EGTYTIEAVDEAPQGTSVTLRLKPEDTEDHLYDYASPYKLKEIVKRYSDFITWPIRMTA
                     ESTATAADTDTEKDEDGEAETPAEPAVETLNSMKALWARSRDEVTDDEYHEFYKHISHD
                     WTNPLETIRMQAEGTFEYQALLFIPSQAPLDLFMRERKRGVQLYVKRVFIMDDCEELMP
                     EYLRFVKGVVDAQDLSLNVSRETLQQDRQIQLMRRRLVKKVLSTVKDMMSANAEGYATF
                     WREFGRAVKEGLLDDFENRDAILEISSFASTHDAEQPTTLRQYMDRMKDGQQHIYYVTG
                     DSRSIIESSPHMEAFQAKGYEVLLLTDPIDEMWVGSVPEFDGKQFQSIAKGDVDLDTEE
                     EKKEGEAEREQQQKDFAELLSWMTTTLSEQVKEVRLSSRLTTSPACIVGDTHDVTPALE
                     NMFRAMGQDMPQIKRILELNPTHPLVTGLREAHGADGSADGLAEMAELIHGMALLAEGG
                     ELGDPARFIKLMSDRLQRTL*"
     CDS             4073..5058
                     /protein_domains="PF13404"
                     /protein_domains="PF01037"
                     /protein_domains="PF13404"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704351"
                     /pseudo=False
                     /translation="MNTDTVTLDDIDRGLVHALQIDGRAPLRTLGEALGVSENTVARRY
                     RRLRSAGVLRVVGALNGGRLGYNAWTIRLRCTPDAAGAIARALAARPDTSYVHLLSGGT
                     EISCSAQTRSSDESDALLLHRLPRTGRITAISAHLLLGHSALPDSWAGPARLTPEQTAL
                     LSPRPVDNAAADADGEVTLDDGDQPLFDVLSRDGRASYAELASATGWSDSTVRRRLTAL
                     RRAGVLAFLVDIPPAALGFRAEARLWMSVRPSRLAEVASALAEHPEVSLVAMTTGPTNL
                     LGAVNCRDAQHLARYLTERIASLDAIRSLETAPVIRTVKRAGALLPI*"
     CDS             5158..6125
                     /protein_domains="PF05448"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704352"
                     /pseudo=False
                     /translation="MALFDLPLDQLRDYRPRVPEPEDFDRFWEKTLAEAREHDLNATFE
                     PVATALTGVAVYDVTFAGFGGHPVKGWFLHPAGAREPLPVVVEYIGYGGGRGLAHTHLL
                     WPAAGFAHLVMDTRGQGSGWASGDTPDPVGSGPAFPGFMTRGIENPEDYYYRRVFTDAV
                     RAVEAARSHPLADPARTAVTGSSQGGGITVAVGGLVPDLVAIAPDVPFLCHFRRAATLT
                     DRDPYREIGNYLRTHRGRDEQIFRTLSYFDGVHFAARGRAPALFSTALEDQTCPPSTVF
                     AAYNAYAVEDKHIEVYSFNGHEGGGPVHQEVQLDWLPPRLR*"
     CDS             complement(6385..7127)
                     /protein_domains="PF13561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704353"
                     /pseudo=False
                     /translation="MGRRIVVSGGGTGIGLATAESFAADGDRVVIVGRRAEVLRAAADK
                     VNAAHGADLVTWTSADLSDPGQTRSAAEFIAADGPVDVVVTNAGGNVAPGNDGTLEGIA
                     DQFQRNFSANVLTAVLLTEALLPHLTRPGGRIVHLSSVAALRGPGSYGGTKAHLHVYTY
                     DLAKRLGAEGITANAVAPGYVQDTEFFGERGTPEFIAQQIGQTLTGQPGYPAEIAAAIR
                     YLASPEAAYVTGQVLHINGGAQFGR*"
     CDS             7502..7977
                     /protein_domains="PF03779"
                     /protein_domains="PF03779"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704354"
                     /pseudo=False
                     /translation="MTEPTHATMESHPDILAMRERHTWAEQAATTPVVQAVEAISLITG
                     LYLAASPWIVGFNGMMTLAVTNLITGVAYAVLMGGFGHAYERTHGMAWAAALLGVWAII
                     APWVVSGSVATMRTIISNVIVGAVALVLALFASSRAKAKASTPGRGGSSARAGR*"
     CDS             8006..8160
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_3704355"
                     /pseudo=False
                     /translation="MTEPYRSTPSQAEGERENDTPGRTVHPDVPVSTPSQAEGEREEEE
                     KNERKK*"
     CDS             8257..9080
                     /protein_domains="PF00296"
                     /protein_domains="TIGR03619"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704356"
                     /pseudo=False
                     /translation="VKIGVSTFVTDQGIGPAPLGRALDERGFDSLFIAEHTHIPASRRT
                     PYPGGGELPEIYYRTLDPFIVLTTIAAVTERLLLGTGIALVPQRDPIIMAKEVASLDLV
                     SGGRVIVGIGAGWNREEMENHGTDPATRGRLVDERLQAMRELWTQEKAEFHGEFVNFDP
                     VYLWPKPVQSPYPPIYVGGGEAAFKRIAALGDAWLANASSPEQLAPLIERLRKVAGRDV
                     PVTVYALTPTPEAVEGYGRLGVERVLFYLPTMPESETLGQLDTMAQVAARFR*"
     CDS             9100..9539
                     /protein_domains="PF01243"
                     /protein_domains="TIGR03668"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704357"
                     /pseudo=False
                     /translation="VPTTTSARARERFARARVARLATLGAEGRPHLVPVVFALTGDTVA
                     TAVDHKPKRSQRLRRLDNIRANPAVCLLVDGYDEDWDLLWWARADGTARVLPPADESAA
                     SAAYVRLLADKYAAQYADRPPTGPVVEIAVDRWSGWQAADTT*"
     CDS             9663..10435
                     /protein_domains="PF03729"
                     /protein_domains="PF03729"
                     /protein_domains="PF03729"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704358"
                     /pseudo=False
                     /translation="MSFSSDDAHGAEQRREQPYGAEQQGAGQRGAEQHSTEPYGTAQRG
                     ERPPEFETPFAGPLGMLSNATWQVMVTTGIIAVALGVMVLAWPGATLAVLGALFGAYLL
                     ITGIFQLAGAFGAHVPGHLRVLSFISGALAVLLGLLCFRGPAQSILLLALWIGFAWLIR
                     GVMVTAAAISQEGLPARGWQIFFGVISLLAGIILIVAPFGSITALAVVAGIWLLALGVI
                     EVFHGVQLRVHLGHHPPREAAHRPHFPRFRPHPQP*"
     CDS             10542..11608
                     /protein_domains="PF13377"
                     /protein_domains="PF00356"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704359"
                     /pseudo=False
                     /translation="MVRKGGGDGGRRTIRDVAARAGVSASTVSRVLGGVYPVSTQTRAR
                     VMRAVRELDYVADAHAKAVAGAGTPTLAFVLDDITGPSFAHMAHGVEREAARLGHLCLV
                     CSTDGDADHEQQFIEMMRAQRAAAVILVGGAADTPDYRRRMARIAESLASAGSRLVLCG
                     RPPLDPGTPVTVIEYDNESGAYALCSHVLAQGHRRVLFLGGKPENTAAQGRERGYVAAH
                     RARGLAPDPVLRLSGDFTRDSGHRLMRQALDAGLEFTAVVAATDMVAAGALTALHEAGL
                     RVPGDVSLAGYDDIPFTRDLHPPLTTVHVPYEELGRLAVRTGLGRTPDTPDEHLLLGTH
                     VVIRDSVAPPAESAR*"
     CDS             complement(11659..12746)
                     /protein_domains="PF00544"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704360"
                     /pseudo=False
                     /translation="MEAERQKAWRSRGWGRLGLTAGLALALGATVGLSDGGAFAPDRGG
                     PGTAVAMDAAAWADDVADGFASVNALGQNGTYGGRGGTTVTVRTLADLEKYATAAEPYV
                     IVVAGAITMDPKGKEIKVASNKTIVGSGTAGQIVGGGFFLGQGVHNVIIRNLTIRDSYE
                     GTWNDKDHDWDGIQMDGAHHVWIDHNDLRHMADGLIDSRKDTTYLTVSWNRLEQHNKAF
                     GIGWTENTTADITIHHNWFHETEQRNPSTDNVAHAHLYNNYLQDDPGTSINSSYGNYAR
                     GNTKMVLENSYFEGMKNPVIKDATASLVQRGSVFANTSGRNESGGTAFDPKSYYPYTLD
                     PAAQVPSIVKSRSGPSSAIGTG*"
     CDS             complement(12825..14041)
                     /protein_domains="PF07228"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704361"
                     /pseudo=False
                     /translation="MVGAEASVSAGTAEALLEELVRTSQEASPAELPEVLDRYVTAMGL
                     GRVVVFLIDLQQRRLLPLTEGEEELEVDGTLAGWAYRTDSLRVTEDGAGGLVVWLPLIN
                     AAERLGLVRFSMKNLDGHRLWRCRALTSILTLIITSKRTYIDTIAQRTRTRPMQLHTEM
                     LRAFLPPRSIGTGRVVSTAVVEPAYELGGDAFDHSFTEDILHATILDAMGHDLASGLTT
                     SVAMAGCRNARRTGAELAQLVMEVDQALTRWLPDQFCTGIFTQLHMPTGMLRWCNCGHP
                     APLLIRRNRLHPKALARPPEPPLGLPASLAGDSRQVYETALEPGDRILLYTDGVVEGRD
                     EGGEQFGLERFADYIIRSTAAGHTASEVLRLLIHAILDQRKNELSDDATILMIEWRPPR
                     GPDPTR*"
     CDS             complement(14067..14872)
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704362"
                     /pseudo=False
                     /translation="MTPAADATTPAVDATTPVLELDDVALRYRGSTAPVVEDVSLTVAA
                     GHSLALVGESGAGKTTLLRLLLGLARPTTGTVRFDGEALRPRDAKLMRRFRGSVQCVFQ
                     DPYSSLDPRRRVGATVAEPLRSLGIDSRRTAAPKVAEALERVGLPADAARRYPHEFSGG
                     QRQRIAIARATVCDPRVLLADEPVSALDVTTRVKVVELLAELQQERGLTIVMVSHDLSV
                     VASLCERTAVLERGRIVEQGDTAQVLGDPAHAYTRRLVDSVPRLPA*"
     CDS             complement(14870..15672)
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704363"
                     /pseudo=False
                     /translation="MTPLLDVRGLTVRTADGRTLVDDLSLSVAPGERLGVIGESGSGKS
                     LTTLAVLGLLPEGMTATGSVELGGTQIVGASEKRLTGVRGRDAAIVFQEPLTALDPLMR
                     VGRQLAGPLRRRRGLTGGALKRAVAEALEQVRLPEPGRIARAFPHEISGGQRQRVALAM
                     ALACEPKLLIADEPTTALDVSVQADMLALIDTLVRDREMAVLFVSHDLAVVAKVTDRAL
                     VMKDGRAVEEGAVDEIVRAPREEYTRTLVASARKLESALAPRSAR*"
     CDS             complement(15670..16565)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_3704364"
                     /pseudo=False
                     /translation="MTRATSPAKPSTKSEAKSEAKSAAKPRAKRSYTLIVGCVLAGLIF
                     LLALVSLVWLPYAADDTSGGRLTGPAADHLLGTDKLGRDLFTQLMTGSRIAVEAGLGSV
                     LIAAAVGVTLGVLTAFAQGWLDDTLSAFLDILIAFPTLLLAMLIVAARSATLGSAVLAI
                     GIAQSAVVARLVRILVKRVLAQDYITAARTSGTSWPRIVAGHVLPNIWPTLVVNLALQF
                     GLAVLAEAGLSYLGLGSPPPNASWGRMLQEAQATFTTAPAGALAPGILLVLLVIGVNLI
                     ADGLRDTLDPATRRRRA*"
ORIGIN
        1 gtgcctctcc ccgagatcga tcccctcacg aacggtgaca tcagcgactc gcctcccagc
       61 agcccggaca ccatagaacc tgacaccgga gatccggacc cgggcgatac gagcgacgcg
      121 ctgcgcgtcc tgcgccgggt cttcggctac gacgcgttcc ggggcgatca gcaagagatc
      181 atcgaccatg tcgtggccgg gggcgacgcc ctggttctga tgccgaccgg cggcggcaag
      241 tcgctgtgct accagatccc cgcgctggtc cgccgcggcg tcggcgtcgt cgtctcgccg
      301 ctcatcgcgc tgatgcagga ccaggtcgac gcgttgcggg cgctcggcgt acgggccggg
      361 ttcctcaact ccacccagga cctggacgag cggcggctgg tcgaggcgga attcctcgct
      421 ggcgagctcg acctgctgta cctcgcgccg gagcggctgc gggtggagtc gacgctctcg
      481 ctgctgggcc ggggctcgat ctcgctgttc gccatcgacg aggcgcactg tgtggcccag
      541 tgggggcacg acttccgccc cgactatctg gccctgtccg agctgcacga gcgctggccc
      601 gatgtgcccc gtatcgcgct gaccgcgacc gccaccgagg ccacccacac cgagatcgcc
      661 tcgcggctca agctgcagga cgcccgccac ttcgtggcga gcttcgaccg gccgaacatc
      721 cagtaccgca tcgcgcccaa gaacgacccc aagcggcagc tgctggagct gctgcgcacc
      781 gagcaccagg gggacgcggg catcgtctac tgcctgtcgc gtgcctcggt cgagaagacc
      841 gccgagttcc tggtgaagaa cgggatcgag gcgctgccgt accacgcggg tcttgacgcc
      901 cggacccggg ccgagaacca ggcgcggttc ctccgggagg acgggctggt cgtggtcgcc
      961 acgatcgcgt tcggcatggg catcgacaag cccgacgtac ggttcgtcgc ccatctcgat
     1021 ctgcccaagt cggtcgaggg ctactaccag gagacgggcc gggccgggcg ggacgggctg
     1081 ccctccaccg cctggctggc gtacggcctc caggacgtcg tccagcagcg caagatgatc
     1141 gacggctcgg agggcgacgc ggcccaccgc cgccgcctcg gcagccacct cgacgcgatg
     1201 ctggcgctct gcgagacggt cgagtgccgc cgggtggggc tgctggccta cttcggtcag
     1261 cggagcaccg catgcggcaa ctgcgatacg tgtctgacgc ccgcggagtc ctgggacggc
     1321 accgtcccgg cgcagaagct gctgtcgacc gtcgtacggc tcaagcggga gcggaaccag
     1381 aagttcggcg ccggtcaggt gatcgacatc ctgctcggca agaagaccgc caaggtgatc
     1441 cagttcgacc atgacgcgct gtccgtgttc gggatcggca cggagctgcg cgaggccgaa
     1501 tggcggggcg tggtgcggca gttgctcgcc caggggctga tcgccgtgga gggggactac
     1561 ggcacgctgg tgctctccga gagcagcggc gaggtgctgg gcgggcagcg ccaggtgatg
     1621 ctgcggcgcg aaccggagcg ggcgccacgg gccgcgaagt cctcgtcgtc gtccgccaag
     1681 tccggccgtg ccgccgcccc ggtggacctg ccgccggagg cggtgccgct gttcgagcgg
     1741 ctgcgcgcct ggcgcggggc caccgccaag gagcagggcg tcccggcgta tgtgatcttc
     1801 catgacgcca cgctgcgcca gatcgcgacg ctgtcgcccg gcaccctggc ggagctcggc
     1861 gcggtcagcg gcgtgggcga gaacaagctg gccaagtacg gggagcagat cctggaaacg
     1921 gtcgcggccg cggaggagtg acgcgtacgg ggggagggcc ggcggccgga cctccccccg
     1981 tacggcgtcc gcgctacagc gtgcgctgca gccggtcgga catcagcttg atgaagcgcg
     2041 ccgggtcgcc gagttcgccg ccttcggcga gcagcgccat accgtggatg agctcggcca
     2101 tctccgcaag accgtccgcg ctcccgtccg cgccgtgggc ctcgcgcagg ccggtcacca
     2161 gcgggtgggt ggggttgagc tcgaggatgc gcttgatctg gggcatgtcc tggcccatgg
     2221 cgcggaacat gttctccagc gccggggtga cgtcgtgggt gtcacccacg atgcacgcgg
     2281 gcgaggtggt gaggcgggag gacagccgca cctccttgac ctgctcgctc agggtcgtcg
     2341 tcatccagga cagcagctcg gcgaagtcct tctgctgctg ctcgcgctcg gcctcgccct
     2401 ccttcttctc ctcctcggtg tcgaggtcga cgtcgccctt ggcgatcgac tggaactgct
     2461 tgccgtcgaa ctccggcacc gacccgaccc acatctcgtc gatcggatcg gtcagcagca
     2521 gcacctcgta gcccttggcc tggaatgcct ccatatgggg cgagctctcg atgatcgagc
     2581 gcgagtcgcc cgtcacgtag tagatgtgct gctgcccgtc cttcatacgg tccatgtact
     2641 gccgcagggt ggtgggctgc tccgcgtcat gggtcgaggc gaacgaggag atctccagga
     2701 tcgcgtcgcg gttctcgaag tcgtcgagca ggccctcctt gacggcgcgg ccgaactccc
     2761 gccagaacgt cgcgtagccc tcggcgttgg cggacatcat gtccttgacc gtcgacagca
     2821 ccttcttgac caggcgccgg cgcatcagct ggatctggcg gtcctgctga agggtctcgc
     2881 gggacacgtt cagcgacagg tcctgcgcgt cgacgacacc cttgacgaag cgcagatact
     2941 ccggcatgag ctcttcgcag tcgtccatga tgaacacgcg cttgacgtag agctgcacac
     3001 cgcgcttgcg ctcccgcatg aacaggtcca gcggggcctg ggacgggatg aacagcagcg
     3061 cctggtactc gaaggtcccc tccgcctgca tgcggatggt ctcgagcggg ttggtccagt
     3121 cgtggctgat gtgcttgtag aactcgtggt actcgtcgtc ggtgacctcg tcccgggagc
     3181 gcgcccacag cgccttcatc gagttgagcg tctcgaccgc gggctccgcc ggagtctcgg
     3241 cctcgccgtc ttcgtccttc tctgtgtccg tatccgccgc cgtggccgtc gactcggcgg
     3301 tcatgcggat gggccaggtg atgaagtcgg agtatcgctt gacgatctcc ttgagcttgt
     3361 acggggaggc gtagtcgtag aggtggtcct cggtgtcctc cggcttcagc cgcagggtga
     3421 cggaggtgcc ctggggcgcc tcgtcgaccg cctcgatggt gtacgtgccc tcgcccgtgg
     3481 actcccagcg ggtgccctgg ctctcggtcg cgtgccgggt caccagcgtg acctggtcgg
     3541 ccaccatgaa gccggagtag aagccgacgc cgaactgccc gatgaggtcc tgcgaggccg
     3601 cggcgtcctt cgactcctcc ttcgagtcct tcagctcgcg aaggaactcg gcggtgccgg
     3661 acttggctat ggtgccgatg agttgcacca catcgtcgtg cgacatgccg atgccgttgt
     3721 cgcgcacggt cagcgtgcgg cgctcctggt ccacctcgag ctcgatgtgg agatcggacg
     3781 tgtccgcgtg caggtcggtg ccacggagcg attccagccg cagtttgtcc aaggcgtcgg
     3841 acgcgttgga gatgagctcc cgcaggaaga cgtccttgtt ggagtagatg gagtggatca
     3901 tcaactgcag gagctggcgc gcctcgacct gaaactcgaa cgtttcggcc ttcgtgttca
     3961 catgcttcct ttcacgagcg agcacttgta gcgagtacct gacgtcagct tagaggcgaa
     4021 ggcccccctc agagggctcg aatggggtgc aaactggcat gctgacggcc gatgaacacg
     4081 gataccgtca ccctcgacga catcgaccgg ggcctggtcc acgccctcca gatcgacggc
     4141 cgggcgccgc tgcgcacact cggcgaagcc ctcggcgtct ccgagaacac cgtcgcccgc
     4201 cgctaccgcc ggctacgctc cgccggggtg ctgcgcgtgg tgggcgccct caacggcggc
     4261 cggctcggct acaacgcctg gaccatccgt ctgcggtgca ccccggacgc ggcgggcgcc
     4321 atcgcccggg cgctggccgc ccgccccgac acctcgtatg tccatctgct ctcgggcggc
     4381 accgagatct cgtgcagcgc gcagacccgc tccagcgacg agagcgacgc gctgctgctg
     4441 caccggctcc cccgtaccgg ccggatcacc gccatctccg cccatctgct gctcggccac
     4501 tccgccctgc ccgacagctg ggcggggccc gcccggctga ccccggaaca gaccgcgctg
     4561 ctcagcccgc gacctgtcga taacgccgca gctgacgccg acggcgaggt caccctggac
     4621 gacggggacc aaccgctgtt cgatgtgctg tcccgggacg gccgggcgag ctatgccgaa
     4681 ctggcgtccg ccaccggctg gtccgactcc acggtgcgcc gccggctgac cgcgctgcgc
     4741 cgcgccgggg tgctcgcctt cctggtcgac ataccgcccg ccgcgctcgg cttccgtgcc
     4801 gaggcgcggc tgtggatgtc ggtgcgcccg tcgcggctgg ccgaggtggc gtcggcgctg
     4861 gccgaacacc ccgaggtgtc gctggtggcc atgaccaccg gcccgaccaa tctcctcggc
     4921 gccgtcaact gccgggacgc ccagcatctc gcgcgctatc tcaccgagcg gatcgcctcg
     4981 ctggacgcga tccgctccct ggagacggcc ccggtcatcc gcaccgtcaa gcgcgccggg
     5041 gcgctgctgc ccatctgacc gggccataca gctgtccgcc cgtgctcccc gcccccttgt
     5101 caggggctgt cgcgcgatgg tttccttcgc aacggcatga agggagctgc ctgtccatgg
     5161 ccctgttcga ccttccgctc gaccagttgc gcgactaccg gccgcgcgtc cccgagcccg
     5221 aggacttcga ccggttctgg gagaagaccc tcgccgaggc ccgtgagcac gatctgaacg
     5281 ccaccttcga gcccgtcgcc acggcgctca ccggtgtggc ggtgtacgac gtcaccttcg
     5341 cggggttcgg cggccacccg gtcaagggct ggtttctgca tccggccggg gcccgggagc
     5401 cgctgccggt cgtggtcgag tacatcggct acggaggcgg acgcgggctc gcgcacaccc
     5461 atctgctgtg gccggccgcg ggcttcgccc acctggtgat ggacacccgc ggccagggca
     5521 gcggctgggc cagcggcgac accccggatc cggtcggctc cgggcccgcg ttcccggggt
     5581 tcatgacccg ggggatcgag aaccccgagg actactacta ccggcgggtc ttcaccgacg
     5641 ccgtacgcgc ggtggaggcg gcccgctccc atccgctggc cgacccggcc cgtaccgcgg
     5701 tcaccggctc cagccagggc gggggcatca cggtcgccgt gggcggtctg gtgcccgacc
     5761 tggtcgcgat cgcccccgat gtgcccttcc tgtgccactt ccggcgggcg gcgacgctga
     5821 ccgaccgcga tccgtaccgc gagatcggca actacctcag gacccaccgc ggccgggacg
     5881 agcagatctt ccgtacgctc tcgtacttcg acggggtcca cttcgccgcc cgggggcggg
     5941 cgccggcgct cttctcgacc gcgctggagg accagacctg tcctccgtcc accgtgttcg
     6001 ccgcgtacaa cgcctatgcg gtcgaggaca agcacattga ggtgtactcg ttcaacggcc
     6061 atgagggcgg cggacccgtc catcaggagg tccagctgga ctggctgccc ccaaggctgc
     6121 ggtagccccc cagccaccga accctcaagc gcaccgacac ccccacagcc cccacagccc
     6181 ccacagcccc caaggacgga cggccgtgcc cggagatggt tgagagcctt cggggaggct
     6241 ccctccggac cggccgtccg tccttcttcc ccccttgcga gggtaaatcc tggctggtgg
     6301 ccgagggcga gggcagggcc gaccggccct tgatccaggg ccgtccggcc ctggacgggc
     6361 aaggccaagc cgacggacgg gacctagcgg ccgaactgcg cgccgccgtt gatgtgcagc
     6421 acctgaccgg tgacataggc ggcctccggg gaggccagat agcggatggc ggccgcgatc
     6481 tcggcggggt atccgggctg cccggtgagc gtctgcccga tttgctgcgc gatgaactcg
     6541 ggagttcccc gctcgccgaa gaactcggtg tcctggacat agccgggggc caccgcgttg
     6601 gcggtgatgc cctccgcgcc caggcgtttg gccaggtcgt aggtgtagac atgcagatgc
     6661 gccttggtgc cgccgtacga accggggccg cgcagcgccg ccacggagga cagatgcacg
     6721 atccggccgc cgggccgggt gagatgcggc agcagggcct cggtcagcag caccgcggtc
     6781 agcacgttgg ccgagaagtt ccgctggaac tggtcggcta tgccttcgag ggtgccgtcg
     6841 ttgccgggcg cgacattgcc gcccgcgttg gtgaccacga cgtcgaccgg accgtcggcg
     6901 gcgatgaact cggcggcgct ccgggtctgc ccggggtcgc tgaggtcggc gctggtccag
     6961 gtgaccaggt cggccccgtg tgcggcgttg accttgtccg cggccgcacg cagcacctcg
     7021 gcgcggcgcc cgacgatgac cacccggtcc ccgtccgcgg cgaaggattc ggcggtcgca
     7081 agaccgatgc ccgtgccgcc gcccgacacc acgatccgtc gtcccattcc ggcctccccg
     7141 tacaccttgt tgaatcccgg tcatattcgt gaacagatgc tagggagcga cgctagggag
     7201 taagcccttt cctgtcaatg gccgcaaggg tgcggccgcg acccgccgtt cggccgcccg
     7261 gccgcgggga taacgcagga cttgcgctcg tccctcgccc cggagggtgt ttgacagtcg
     7321 acgggtggct ctattcggtg tgccagcgcg agccggagcc ggccgcggcg ccgggcgagc
     7381 ccggccacta gcggccgaaa tctgcgcgca cggggccgcg aagtttctgg cgacccgagc
     7441 gttatgaggg gacatatcgg gcacccgggg ttcggagcga attgaccgca ggaggcgatc
     7501 atgacggaac cgacccatgc gaccatggag tcccatccgg acatcctggc gatgcgggaa
     7561 cgccacacct gggccgaaca ggccgctacc acgcccgtgg tccaggccgt cgaagcgata
     7621 tccctgatca ccggtctgta ccttgccgct tccccgtgga tcgtgggttt caacggcatg
     7681 atgacgctgg ccgtgaccaa cctgatcacc ggagtcgctt acgcggtgct catgggcggc
     7741 ttcggccatg cctatgaacg cacccatggc atggcctggg ccgccgcgct gctgggcgtc
     7801 tgggcgatca tcgcgccgtg ggtggtgtcg ggcagcgtgg ccaccatgcg caccatcatc
     7861 agcaacgtca tcgtcggcgc tgtcgcgctg gtgctcgcac tgttcgccag ctcgagggcg
     7921 aaggcgaagg cgtccacccc gggccgcggg ggctcatccg ctcgcgcggg gcgctgacgg
     7981 cccgggacag aacggaggca tgcgatgact gagccctacc gttccacccc gtcccaggcg
     8041 gaaggcgagc gcgagaacga cacacccggc cgcacggttc accccgatgt gccggtgtcg
     8101 accccctccc aggcagaagg ggagcgcgag gaggaagaga agaacgagcg gaagaagtaa
     8161 acaaccaggc catgagggct cggaggcccc ggtgcccggg ccgagccggg ccggtgacgg
     8221 cggtcaccgg ccctcctcga caagaaggag ccgccgtgaa gatcggtgta tcgaccttcg
     8281 tcaccgacca gggaatcggg cccgccccgc tggggcgcgc cctcgacgag cggggcttcg
     8341 actcgctctt catcgccgag cacacccata tcccggcgag ccgccgtacg ccctacccgg
     8401 gcggcgggga gctgccggag atctactacc gcacgctcga cccgttcatc gtgctgacca
     8461 ccatcgccgc ggtcaccgag cggctgctgc tgggcacggg catcgccctg gtgccacaac
     8521 gggacccgat catcatggcg aaggaagtgg cctcgctcga ccttgtctcc ggcgggcgcg
     8581 tcatcgtcgg gatcggcgcc ggatggaacc gcgaggagat ggagaaccac ggtacggacc
     8641 cggccacgcg aggccggctg gtcgacgagc gactgcaggc gatgcgtgag ctgtggaccc
     8701 aggagaaggc cgagttccac ggggaattcg tcaacttcga cccggtgtac ctgtggccca
     8761 aaccggtgca gagcccgtat ccgccgatct acgtgggcgg cggcgaggcc gccttcaagc
     8821 ggatcgccgc cctcggcgac gcctggctcg ccaacgcctc gtcgccggag cagctggccc
     8881 cgctgatcga gcgactacgg aaggtggccg gccgggacgt gccggtgacg gtgtacgcgt
     8941 tgacccccac accggaggcg gtcgagggat acgggcggct gggtgtggag cgggtcctgt
     9001 tctatctgcc gaccatgccg gagagcgaaa cactcggcca actcgacacg atggcccagg
     9061 tcgccgcccg gttccggtga gccgccggga gccgcgcggt gcccacgacg acaagtgccc
     9121 gggcgcggga gcgcttcgcg cgggccaggg tggcccgact ggcgaccctc ggcgccgagg
     9181 gccggcccca tctggtgccg gtggtgttcg cgctgaccgg cgacacggtg gcgacggcgg
     9241 tcgaccacaa gccgaaacgc tcgcagcggc tcagacgcct ggacaacatc cgggccaacc
     9301 ccgccgtatg cctcctggtg gacggctacg acgaggactg ggacctcctg tggtgggcgc
     9361 gggccgacgg tacggcccgc gtcctgccgc ccgccgacga gtcggccgcc tccgccgcgt
     9421 acgtacggct gctggccgac aagtacgcgg cgcagtacgc ggaccggccg ccgacggggc
     9481 cggtcgtgga gatcgcggtc gaccggtgga gcggctggca ggccgccgat accacctgaa
     9541 accatccggc gccgcccgag accgcccgag accacttgcg ccgccaggcg aagagaccca
     9601 tccggggaga ggatggtggt gtcgggtacg tccttctgtt ccatcaagga ggtggacggc
     9661 catgagtttc tcctccgacg acgcacacgg cgccgaacag cggcgcgagc agccctacgg
     9721 cgccgaacag caaggtgcgg ggcagcgggg cgctgagcag cacagcacag agccgtacgg
     9781 cacggctcag cgaggcgagc ggcctccgga gttcgagacc ccgttcgccg gtcccctggg
     9841 catgttgtcc aacgccacct ggcaggtcat ggtgaccacg ggcatcatcg cggtcgcgct
     9901 gggcgtcatg gtgctggcct ggccgggggc aaccctggcg gtgctcggcg cgctgttcgg
     9961 cgcgtatctg ctgatcaccg ggatcttcca gctggcgggg gccttcggcg cccatgtgcc
    10021 ggggcatctg cgcgtactga gcttcatcag cggcgcactc gccgtactgc tcggcctgct
    10081 ctgcttccgg ggaccggcac agtcgatcct gctgctggcc ctgtggatcg ggttcgcctg
    10141 gctgattcgc ggcgtcatgg tgaccgccgc ggccatctcc caggaagggc ttccggcccg
    10201 cggctggcag atcttcttcg gtgtcatcag cctgctggcc ggcatcatcc tgatcgtcgc
    10261 gcccttcggc tccatcacgg cgctcgccgt ggtggccggc atctggctgc tggcgctggg
    10321 agtgatcgag gtgttccacg gtgtccagct gcgggttcac ctgggccacc accctccgcg
    10381 cgaggcggca caccgcccgc acttcccgcg cttcaggccg catccccagc cgtagtcccg
    10441 gtcatggccc tccccccgcg gctcccccgc tgttagcctc tggtgtggca accggttgtc
    10501 atgcggttac ccggctcggg ggcacagcga ggggtgggcc atggtgcgga agggcggcgg
    10561 cgacggggga cgtcgtacga tccgggatgt cgcggcccgc gcgggggtgt ccgcgtccac
    10621 ggtgtcgcgg gtgctcggcg gcgtgtaccc ggtcagtacg cagacccgtg cccgggtgat
    10681 gcgggcggtc cgcgagctgg actatgtcgc cgacgcccac gccaaggcgg tggcgggcgc
    10741 cggcaccccg acgctcgcgt tcgtcctcga cgacatcacc ggcccgtcgt tcgcgcatat
    10801 ggcacacggc gtggagcgcg aggcggcccg gctcggccat ctgtgcctgg tgtgcagcac
    10861 ggacggcgac gccgaccacg aacagcagtt catcgagatg atgcgcgccc agcgcgccgc
    10921 cgccgtgatc ctggtgggcg gcgccgcgga cacccccgac taccgccggc gcatggcccg
    10981 tatcgccgag tcgctggcct cggccggctc acggctggtg ctgtgcgggc ggccgccgct
    11041 ggatcccggc accccggtga cggtcatcga gtacgacaac gagagcgggg cctacgcgct
    11101 gtgctcgcat gtcctcgccc agggccaccg gcgggtcctc ttcctcgggg gcaaaccgga
    11161 gaacaccgcg gcccaggggc gcgagcgtgg ctatgtggcc gcgcaccgcg cccggggcct
    11221 ggctccggac ccggtgctgc ggctgtccgg cgacttcacc cgcgactcgg gccaccggct
    11281 gatgcgccaa gccctcgacg cagggctgga gttcaccgcc gtggtggccg ccacggacat
    11341 ggtcgcggcg ggggcgctca ccgcgctcca cgaggcgggg ctgcgcgtac ccggcgatgt
    11401 gtcgctcgcc gggtacgacg acatcccgtt cacccgggat ctgcatccgc cgctgaccac
    11461 ggtccatgtg ccctacgagg agctgggccg gctcgccgtc cgtaccggcc tcggcagaac
    11521 gccggacacc ccggatgaac acctgctcct gggcacccat gtggtgatcc gcgactcggt
    11581 ggccccgccg gcggagtcgg cccggtaacc actgcccggc aaccgctgcc cggcaaccgg
    11641 tttctgggcc gtggccgtca gccggtgccg atggcggagc tgggcccgga gcgggacttc
    11701 acgatcgagg gcacctgggc ggcggggtcc agggtgtacg ggtagtacga cttcgggtcg
    11761 aaggccgttc cgccgctctc attgcgcccg gaggtgttcg cgaacacgct gccccgctgg
    11821 accagggagg cggtggcgtc cttgatcacc gggttcttca tgccctcgaa gtagctgttc
    11881 tccagcacca tcttggtgtt gccgcgggcg tagttgccgt acgaggagtt gatgctcgtc
    11941 cccgggtcgt cctgcagata gttgttgtac agatgcgcgt gcgcgacgtt gtcggtggac
    12001 gggttgcgct gttcggtctc gtggaaccag ttgtggtgga tcgtgatgtc ggcggtcgtg
    12061 ttctccgtcc agccgatgcc gaacgccttg ttgtgctgct ccagccggtt ccaggacacc
    12121 gtgagatagg tggtgtcctt acggctgtcg atcaggccgt cggccatgtg ccgcagatcg
    12181 ttgtggtcga tccacacatg gtgggcgccg tccatctgga tgccgtccca gtcgtggtcc
    12241 ttgtcgttcc acgtgccctc gtaggagtcg cggatcgtca ggttgcggat gatgacgttg
    12301 tgcacgccct ggccgaggaa gaaaccgccg ccgacgatct ggcccgcggt ccccgagccc
    12361 acgatcgtct tgttcgaggc gaccttgatc tccttgccct tcgggtccat ggtgatcgcc
    12421 ccggccacca cgatgacgta cggctcggcg gccgtcgcgt acttctccag atcggcgagc
    12481 gtgcgcacgg tgacggtcgt cccgccgcgg ccaccgtatg tgccgttctg tcccagcgcg
    12541 ttgaccgagg cgaacccgtc ggcgacgtca tcggcccacg ccgccgcgtc catcgccacc
    12601 gccgtacccg gtccgccccg gtccggcgcg aaggcaccgc cgtcgctgag acccaccgtg
    12661 gcgcccagcg ccagggccag tccggccgtc aggccgagcc tgccccagcc cctgctgcgc
    12721 cacgccttct gtcgctcggc ttccatggct acctcttcca cagctcgggg gatgtcgtcc
    12781 atgcccctgt cgccgccgcg cgccgagagg ttgccccatc gcgtcaccgg gtcgggtcgg
    12841 gtcctcgggg gggccgccat tcgatcatca gaatggtggc gtcgtcgctg agttcgttct
    12901 tccgctggtc gaggatggcg tggatgagca ggcggagcac ttcggaggcg gtgtgcccgg
    12961 cggccgtcga ccggatgatg tagtcggcga agcgctccag gccgaactgc tcgccaccct
    13021 cgtcccgccc ttcgacgacc ccgtcggtgt agagcaggat ccggtccccg ggttcgagcg
    13081 ccgtctcgta cacctgccgg ctgtcgccgg ccaggctggc gggcaggccg aggggcggtt
    13141 cggggggccg cgccagcgcc ttcgggtgca gccggttgcg gcggatgagc agtggcgccg
    13201 gatggccgca gttgcaccag cggagcatgc cggtgggcat gtgcagctgg gtgaagatgc
    13261 cggtgcagaa ctggtcgggc agccaccgtg tcagcgcctg gtccacctcc atgaccagct
    13321 gcgccagctc cgcgccggtc cgccgggcgt tgcggcagcc cgccatggcc acggaggtgg
    13381 tgaggccgga cgccaggtcg tggcccatgg cgtcgaggat cgtggcgtgc aggatgtcct
    13441 cggtgaacga gtggtcgaag gcgtcgccac ccagctcgta cgcgggctcc acgaccgcgg
    13501 tcgacaccac ccggccggtg ccgatcgagc gcggcggcag aaacgcccgc agcatctccg
    13561 tgtgcagctg catgggccgg gtgcgggtgc gctgcgcgat ggtgtcgata taggtgcgct
    13621 tggaggtgat gatcagggtg aggatcgagg tcagtgcccg gcagcgccag agtctgtgcc
    13681 cgtccaggtt cttcatcgag aagcgcacga ggcccagccg ctccgccgcg ttgatcagcg
    13741 gcagccatac gaccagaccg ccggcgccgt cctcggtcac ccgcagggag tccgtgcggt
    13801 acgcccagcc ggccagggtg ccgtcgacct ccagctcctc ttcgccctcg gtcagcggca
    13861 gcagccgcct ttgctggaga tcgatgagaa acacgacgac ccggcccagg cccatggccg
    13921 tgacatagcg gtccaggacc tcggggagct ccgcggggga agcctcctgg gaagtcctga
    13981 ccagctcttc cagcagggct tccgcggttc cggccgatac cgacgcctcc gcgcccacca
    14041 tagggtcaac tgtacggaat cccgctcagg cgggcaggcg cggcacactg tcgacgaggc
    14101 ggcgggtgta cgcatgcgcc gggtcgccca gcacctgggc ggtgtcgccc tgctccacga
    14161 tgcggccgcg ctccaggacc gcggtgcgct cgcacaggga cgcgaccacc gacagatcgt
    14221 gggagaccat gacgatcgtc agcccccgct cctgctgcaa ctcggccagc agctcgacga
    14281 ccttgacccg ggtcgtgacg tcgagcgcgc tgacgggttc gtcggcgagc agcacccgcg
    14341 ggtcgcatac ggtggcgcgg gcgatcgcga tgcgctgccg ctggccgccg gagaactcgt
    14401 gcggatagcg ccgcgccgcg tcggccggca gcccgacccg ctccagggcc tcggccacct
    14461 tgggcgccgc cgtacgcctg ctgtcgatgc cgagcgagcg cagcggctcg gccacggtgg
    14521 cgcccacgcg gcggcgcggg tcgagcgagg agtacgggtc ctggaagacg cactgcacgc
    14581 tgccgcggaa gcggcgcatc agcttggcgt cgcgggggcg cagcgcctcg ccgtcgaagc
    14641 gcacggtgcc ggtggtgggc cgggcgagcc cgagcagcag gcgcagcagg gtcgtcttgc
    14701 ccgcgcccga ctcgccgacc agggcgaggc tgtgtccggc cgcgacggtg agggacacgt
    14761 cctcgacgac gggggcggtg ctcccccggt agcgcagcgc gacgtcgtcc agctccagta
    14821 cgggggtcgt cgcgtccact gcgggtgtcg tcgcgtccgc tgcgggggtc atcgcgcgct
    14881 cctcggggcc agggcggact ccagctttcg cgcgctggcc accagtgtcc tggtgtactc
    14941 ctcgcgcggc gcgcggacga tctcgtcgac ggcgccctcc tccacggcgc ggccgtcctt
    15001 catgaccagc gcccggtcgg tgaccttggc gacgaccgcc aggtcgtggc tgacgaacag
    15061 gacggccatc tcacgatcgc gcaccagggt gtcgatcagg gcgagcatgt cggcctgtac
    15121 ggacacgtcc agcgcggtgg tcggctcgtc cgcgatgagc agcttcggct cgcaggccag
    15181 cgccatggcc agcgccacgc gctggcgctg cccgccggag atctcatgcg gaaaggcgcg
    15241 ggcgatacgg cccggctcgg gcagccgcac ctgctccagc gcctcggcga cggcccgttt
    15301 gagggcgccg ccggtcagcc cccgccgccg gcggagcggt ccggcgagct gccggcccac
    15361 ccgcatcagc gggtcgagcg cggtcagcgg ctcctggaag acgatggcgg cgtcccggcc
    15421 gcgtacgccg gtgagccgct tctcgctcgc gccgacgatc tgggtgccgc ccagttcgac
    15481 gctgccggtg gcggtcatgc cctcgggcag cagcccgagg acggcgaggg tggtcagcga
    15541 cttgccggag cccgactcgc cgatgacgcc gagccgttcg ccgggggcga cggacagcga
    15601 gaggtcgtcc acgagggtgc gcccgtccgc cgtgcgtacg gtgaggccgc gtacgtcgag
    15661 gaggggggtc atgcgcgcct ccgccgggtc gccgggtcga gggtgtcgcg caggccgtcg
    15721 gcgatcaggt tgacgccgat gaccagcagt acgagcagga tgccgggggc gagcgcaccc
    15781 gccggggcgg tggtgaaggt ggcctgggcc tcctggagca tccggcccca tgaggcgttg
    15841 ggcggcgggg atcccaggcc caggtaggag agcccggcct cggccagcac cgcgaggccg
    15901 aactggagcg ccaggttgac cacgagggtg ggccagatgt tgggcaggac gtgtccggcc
    15961 acgatccggg gccaggaggt gcccgaggta cgggcggccg tgatgtagtc ctgcgcgagc
    16021 acccgtttga ccagaatgcg caccaggcgg gccacgaccg cgctctgtgc gatgccgatc
    16081 gccagcacgg ccgaccccag ggtggccgag cgggcggcga cgatcagcat ggcgagcagc
    16141 agcgtcggga aggcgatcag gatgtcgagg aacgcggaga gcgtgtcgtc gagccagccc
    16201 tgcgcgaacg cggtcagcac gcccagggtg accccgaccg cggccgcgat gaggacggag
    16261 ccgagccccg cctcgacggc gatccgggag ccggtcatca gctgggtgaa caggtcgcgg
    16321 ccgagcttgt cggtgcccag cagatggtcg gcggcggggc cggtgagccg tccgccggag
    16381 gtgtcgtcgg cggcgtacgg gagccagacc agggagacga gggcgagcag gaagatcaga
    16441 ccggccagga cgcagcccac gatcagcgtg tacgaccgct tggcccgggg cttggccgcg
    16501 gatttggcct cggacttggc ctcggacttg gtggagggct tcgccgggga tgtcgcgcgc
    16561 gtcat
//
