LOCUS       reptomyces_RBGC_423916 16640 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_423916
VERSION     Streptomyces_RBGC_423916
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000952035.2
  ORGANISM  GCF_000952035.2
            .
FEATURES             Location/Qualifiers
     CDS             2..2079
                     /protein_domains="PF07690"
                     /protein_domains="TIGR00711"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589087"
                     /pseudo=False
                     /translation="MAQDTSAPAIPGAGRSQRTVLVAIGALLLGMLIAALDQTIVATAL
                     PTIVSDLGGLDHLSWVVTAYLLASTAATPLWGKLGDQYGRKKLFQTAIVIFLIGSVLCG
                     IAQDMAQLIAFRALQGLGGGGLIVLSMAIVGDIVPPRERGKYQGLFGAVFGGTSVLGPL
                     LGGLFVDHLSWRWVFYINVPVGIVALAVIAAVLHIPRRRTPHRIDYLGTALIAAVAACF
                     VLMTSLGGVTYPWSSWQIVGFGVLGVLLLGAFVLVERRAAEPVLPLRLFTLRTFTLCAV
                     IGFVIGFAMFGSMTYLPTFLQVVQGVSPTMSGVHMLPMVLGMLLSSTASGQIVSRTGRY
                     KVFPVLGTAVVALGLLLLHQLDPASSVAEMSGYFFVFGFGLGLVMQVLVLIVQNAVPYQ
                     DLGVATSGATFFRSIGASFGVSIFGTVFANKLGPRIAHALAGQQLPPGVDPSRIAEDPR
                     TVTRLPAGTAARVLDAYSVSITDVFLYAVPVVLVAFTLSWFLKEEPLRASVTAPETSEV
                     VSSNPVERSSRDECARALSKLGSMEGRKHIYEKITARAGLDLRPAASWLLLRIQHYGSV
                     EPALLVERTNVPLGVISEGVRQIEERGLAAREGLMLLLTDRGREAAGRLSDARQESLAE
                     LLGDWWTEDRPTDLTEIVRELSAELCGSDAEEPHDGNARQPVARTPHRTPRPPGVPK*"
     CDS             2317..2453
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_4589088"
                     /pseudo=False
                     /translation="MEEQNELSNVEPYAPPMLVEVGEFSEDTLGFIGWGKDIFGHYGGR
                     *"
     CDS             2488..4322
                     /protein_domains="PF00733"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589089"
                     /pseudo=False
                     /translation="MTGAGFVVLPDTASAAEARAVVPWAAPRVHSHASGRPWLVGRWLP
                     GEIQVVTAGPVRVAVIGVCPVTATRLSELTARIRTVSDVDTLAAALPGSCHVVASVDGR
                     LRVQGSLTGLRRVFHTRVNGLTVAADRADVLAAMTGAGIDERALAVRLACGGLVPPALG
                     DRPLWKGVTPLAPDHYLLWDGERTRDVRWWQPPAPEQPLSAGARAVREALTSALQDRGP
                     AEGRLSTDLSGGMDSTSLCFLAARSVPDLLTFRWGEAEAGNDDAAFAAHSIDALDRADH
                     VVVPPAELPALYADADVLMDTEEPYPFVRTAARTHHTARLLAARGSHRHLAGHGGDELF
                     TPFSGYLHGLLRRHPVAALRHVRGYAALERWPLLHTLASLVRPGDEASWWRAQADHLTD
                     PPLRKRRPSLGWGLWPLHAPSYVTGTAVAEAREVLRHTADTTRPLSRDLGQHQLLLAVR
                     TSAPWYRLLARPFAEAGVQLDSPFFDDRVVEAVAGVRVHEHSGPWRYKPLLAEAMRGIV
                     PETVLGRSTKGEFSEEANSGLRRNLPAILELFDDSALAAHGLIDSGELRTRLLAPQADN
                     AMSIALEPLIGCETWLRAATRPTPAWRFDAHASAS*"
     CDS             4307..4557
                     /protein_domains="PF05402"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589090"
                     /pseudo=False
                     /translation="MRLHPDVVSTDTDDGTVLLNGRTGRYWQLNATGAHVLRGLLDGDS
                     PDDIAAGVATRHRIDPSRAERDVTTVIDQLRTAGLVIA*"
     CDS             4555..4982
                     /protein_domains="PF13471"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589091"
                     /pseudo=False
                     /translation="VSLPVALSERRRLPLHRRLVPLLAVGIARLLAKAKPARLRTVLEF
                     ARRGASPATADQALEARAAVVSVSLRCAGQGCLQRSIATALLCRTRGVWPTWCTGVRTH
                     PFAAHAWVEADGEPVGEPHPKGHFKPLISIPPLRSGEG*"
     CDS             complement(4996..5624)
                     /protein_domains="PF00583"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589092"
                     /pseudo=False
                     /translation="VSVAARAAEIACVPLPGRGDNAAMSQTAALRLPWTVSAEPWGSPD
                     ARALLRDYYTEVADRYFALHEGRRATPEEIAEGLAEYPDDHLTPPHGVLLIARYGDAVA
                     GCAGVRLLDERTAELKQMFVRIPYRGRGGAGGLLTAAESAAVRMGAGRIRLDTRLDLVE
                     AIALYRRHGFTEIPRYHDDIYAEIFFEKRLGVFEERLGVCEERLGG*"
     CDS             complement(5653..5978)
                     /protein_domains="PF03992"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589093"
                     /pseudo=False
                     /translation="MSVVKINVLTVPAEQRETLEKRFASRAHAVESSDGFEWFELLRPV
                     EGTDQYLVYTRWRDEESFQAWMEGPMKAAHQGGGEGGERPKPAATGSTLWSFEVVQQAS
                     PKKG*"
     CDS             complement(6303..7204)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589094"
                     /pseudo=False
                     /translation="MTYNLFLVDSCGPDVLAEALAAILHVPVKEVDVADPDGDQEGRYW
                     DALVSCDYSPVQGNVSLSLNIYAQESVEQQPSEAQLSAALAQRIGTPVLYPPDESPVSA
                     HSLVTPEGEVIRARLPDPDDEEFMVTAVEAFVEQLPDVPVIHLPEVVRAQAIATPLSDS
                     FAEAVANLSQDGQGEGAGAVTAEVAEVARFAESYLGAWEKLSRRAENNWEPSGWYPLDF
                     YREVLEYRDDIEGYLRQLPESIATLYKRYVDKVDSLYQELTVEDKEHVVIGDSHRPITD
                     SVQKAWWWYRRPEPMPWEE*"
     CDS             complement(7202..8559)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589095"
                     /pseudo=False
                     /translation="LSAGDKAKEIVQDLTGMWWPEGDEDELREAARAWRTFADDVKDIT
                     SATHKSAQDIIDNNKGKSIDAFASFWRKYHGGGKGYLDDVADAARDMAKALDKFADQIA
                     EATKKLEHELAIAGAVIVAGTALALFTAGISEAAAGAATAEILAASSAAGIAVSTTVAE
                     IAGTVLATAAIGGIEAITVDVVVAQGGRNLLGDQHGINLAEVKDAGTSGMLLGGAFGAA
                     GRGAKAIADAGGFKNAFGKMKLDGLGNFKNSLRDFEISIPNLGGPRLTMAGAGPVGPAT
                     GWRLMRNAEGGGGGASGTPKASGWEVSPDVKGPAAGKTLRPPNDRHTIGGAARAGKNIK
                     KENTIILPGFYSEVEKDIAGIAEGKAALTPKGDAYIINGREYSVHPENGTVYPCRGPGL
                     VEMDRNEYYVLSRIAKAKGDLSAVPELTHAPRFVNNPQMVEKALAIYNGTYTP*"
     CDS             complement(8557..8885)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589096"
                     /pseudo=False
                     /translation="VAASGFDVDTDQLKSEAPKFHRESVALEKATEKLKHSLDALGEPW
                     GDDEQGKKFGHIYSPHRHKIERAAHALVKGLESIHKAMKDMADNHEDTDHSNASGFKRH
                     GGGTH*"
     CDS             complement(9140..9279)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MVGRHPDASLHHTGAAAVGVALTLMMALASSRHPGSKRLAASVQQ
                     T"
     CDS             complement(9220..9392)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MAGLRIDEEPPALSHQTAARPGSGVGNTHRRSDSGLPTWSDGTPT
                     PACITQGQLLSA"
     CDS             complement(9455..9600)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589097"
                     /pseudo=False
                     /translation="MSIVKINVLTVPAEQREVLEQRFGARAGTVDSADGFEWFELLRPQ
                     RVL*"
     CDS             complement(9666..10150)
                     /protein_domains="PF09391"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589098"
                     /pseudo=False
                     /translation="MTTPITSPAVTPPALATAPAAGPGPRFETKIAVIVREDLAVWQKL
                     NVTAFLASGIAHSADDIMGRHRYEDASGNDYLALFREPVLCFTADSGALSRTHARALSR
                     AVPTAVYTTEMFRTGNDDDNRASVRAVAAGDLDLVGLAVYGPRNTIDKITKGLKLHG*"
     CDS             10220..11154
                     /protein_domains="PF12833"
                     /protein_domains="PF02311"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589099"
                     /pseudo=False
                     /translation="MNGRRDGDAGDTREHGDTRERGGTGGGDWARYWRDPERPLEAMHA
                     HFVRHVFHPHSHDAYSFAVTEAGAQRFTCRGAGHTSAAGMVMAFNPDDPHDGESAVDLG
                     FTYRIMHIGPDVVRDVLDDVTGGRGSMPLFAQPVVDDPVLARALRRLHPALVGAADPLV
                     REERLGAAVEAMVRRNASRGAAQSGPRELTGGAQTRAARRVRDLLRAAYDQPLTAQDLA
                     DAAGCSRFALYRAFRTAYGMSPSDYQRLLRLRHARTLLIGGRPASEAATEAGFADQAHF
                     HRWFVRCFGITPGAFRRAAAVTQCPGPARS*"
     CDS             complement(11150..12264)
                     /protein_domains="PF10092"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589100"
                     /pseudo=False
                     /translation="MGAASARRVGSIRRRQALLVVLMLLAMQLVALARPAYACGCGAMV
                     VDPKTTMSVDRETSAVHWDGRTEQIVMSLTVHGDAPDAAWIMPVPHRATVKLGDRALFD
                     ELASLTKPVEKDRSYFWPHGGDWPFRWSDGDTAAAPAPGAAGPGVGLVGRERLGPFDVA
                     RLTATDPDALRGWLTSHGFRLPSSLATGLRPYVAQHWEYVAIRLAPAQKYGFLNGTLDP
                     LRLSFASDRLVYPMRLSRLATTQQSLGLYVLAPHRMEPRGAIGGSAPEVFFAGRIKTKG
                     TPVSALAGTGGAFLTAIDQRFPHPERISGDHELRRAAADTPYRRVHYTDVLMKVGGVPV
                     WVLVVGGVLLLVVIALTVRRRRRRRRDVSGS*"
     CDS             complement(12434..13959)
                     /protein_domains="PF00083"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589101"
                     /pseudo=False
                     /translation="MQSSKRAQASEHVPTQSPVASGAPTHGRSPSRTDAAPDLEKRTSD
                     EVTVVDPAMVRRAVSAAALGNAMEWFDFGVYSYIAVTLGHVFFPSGNPTAQLLSTFGAF
                     AAAFLVRPIGGMVFGPLGDRIGRQKVLAITMIMMAAGTFAIGLIPSYATIGVGAPILLL
                     VARLVQGFSTGGEYGGASTFIAEYAPDKKRGFLGSWLEFGTLAGYVGGAGLVTLMTALL
                     STHDLHAWGWRIPFLIAGPMGIIGLYLRMRLEETPAFARLEKEARTKEKERREAEKRIG
                     VREMVFGQWRAMLLCVGLVLVFNVTDYMLLSYMPSYLTSELKYDETHGLMVVLGVMVVM
                     MGVQPFAGRLSDRFGRRPVIAAGCAGFLVLSVPALLLIRQGSLAAIALGMGALGLLLVC
                     FTAAMPSALPALFPTKVRYGSLSIGFNISVSLFGGTTPLVVTALIGATGNKMMPAYYMM
                     AAAVIGGIAVWRMSESARRPLPGSPPAVETEAEAREIVRASRGAEAASAA*"
     CDS             14539..15542
                     /protein_domains="PF00248"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589102"
                     /pseudo=False
                     /translation="VKTRRLGSGEHSAPVSAIGLGCMGMSVAYGPADADEARRTLDRAA
                     ELGVTFLDTADAYGRGANEELIGHWMRDRGRRADVFLATKFGLRHDAATGRVDTVDTSP
                     QYVPAACDASLRRLGVDRIDLYYAHRRDPATPVEDTVGAMAELVSAGKVAHLGLSEVSP
                     ATLRAAHAVHPIAAVQLEYSLFTRDVVEGEMLATCRELGISVVAYSPLGRGMLAGALAS
                     RDELTEEDNRRRWPRFSADNIGRNLALVHEVRRLAAEIGVTPAQAALGWLLAQGDDIVP
                     IPGTKRVRYAEENAAAAGTGLTPEQAERLRAAVPGAAVAGARYPEQALRRLGH*"
     CDS             complement(15592..16640)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4589103"
                     /pseudo=False
                     /translation="MGDELDLLRAADPARADDGPWRDGPLHARAERGLNRLLHSARTKR
                     ARRRLVLRAEAAVLALGAALAFTFSDAGSGKAVAMPVALAPRADAPAVPLAELARRAEA
                     RARTAGAADGPHRGSHLQSWYLSMETGPDAAPPVTVPEERITRWRADGSGSELVVATDP
                     RHPGRPVINDTGGSWHTVNDGKVLHRKTYPAGSADGQRQRRLAARTKPPTDPGALRDRL
                     ATLYGGGGGGRGDTAGPAGARTPQLLLALSSLRQEWTPGPRETAAIVRVLADAEGLRPA
                     GAVTDRLGRRGQAYVYDGPDGGRNATRQMVILDPRTGQLLGSEITFTKNLPDVRIRSGE
                     VLSYEAWMP*"
ORIGIN
        1 atggcgcagg acaccagcgc tccggcgata cccggtgcgg gccggtccca gcggacggtc
       61 ctcgtcgcga tcggtgcgct gctgctcggc atgctgatcg cggcgctcga ccagaccatc
      121 gtcgccaccg cgctgcccac catcgtcagc gacctcggcg gcctcgacca tctgtcctgg
      181 gtggtcaccg cctacctcct ggcctcgacg gccgcgacac cactgtgggg caaactcggc
      241 gaccagtacg gccgcaagaa gctgttccag accgcgatcg tgatcttcct gatcggctcg
      301 gtgctctgcg gtatcgcgca ggacatggcg cagctgatcg ccttccgggc cctccagggg
      361 ctgggcggcg gtggtctgat cgtgctgtcg atggcgatcg tcggcgacat tgtgccgccc
      421 cgggaacgcg gcaagtacca gggcctgttc ggcgccgtct tcggcggtac cagcgtcctg
      481 ggaccgctgc tgggcgggct gttcgtcgac cacctcagct ggcgctgggt cttctacatc
      541 aacgtccccg tcggcatcgt cgcgctggcc gtcatcgccg ccgtactgca catcccgcgc
      601 cgccgcaccc cgcaccggat cgactacctg ggcaccgccc tgatcgccgc cgtcgccgcc
      661 tgcttcgtgc tgatgacctc gctcggcggc gtgacctacc cctggagctc ctggcagatc
      721 gtgggattcg gcgtgctggg cgtccttctg ctgggcgcgt tcgtcctggt ggagcgccgg
      781 gccgccgaac ccgtcctccc cctgcgcctg ttcaccctgc gcaccttcac cctctgcgcc
      841 gtcatcggct tcgtcatcgg cttcgccatg ttcggctcga tgacgtatct cccgacgttc
      901 ctgcaggtcg tacagggcgt ctcgccgacc atgtccggtg tgcacatgct gccgatggtg
      961 ctcggcatgc tgctctcctc caccgcctcc gggcagatcg tctcccgcac cggccgctac
     1021 aaggtcttcc cggtcctcgg caccgccgtg gtcgccctcg gcctgctgct cctgcaccag
     1081 ctcgaccccg ccagcagcgt cgccgagatg agcggctact tcttcgtctt cggcttcggg
     1141 ctcggcctgg tcatgcaggt cctggtgctc atcgtgcaga acgccgttcc ctaccaggac
     1201 ctcggcgtgg ccacctccgg cgccacgttc ttccgctcca tcggcgcctc gttcggcgtc
     1261 tccatcttcg gcacggtctt cgccaacaag ctcggcccgc ggatcgccca cgccctcgcc
     1321 gggcagcaac tgccgcccgg tgtcgacccg tcgaggatcg ccgaggaccc gcgcaccgtc
     1381 acccggctcc cggccggaac ggcggcccgc gtcctggacg cctactccgt ctccatcacc
     1441 gatgtcttcc tctacgcggt cccggtcgtc ctcgtcgcct tcaccctgtc ctggttcctc
     1501 aaggaggagc cgctgcgcgc cagcgtcacc gcccccgaga ccagcgaggt ggtctcctcc
     1561 aaccccgtcg agcggtcctc gcgcgacgaa tgcgcccgcg ccctgtccaa gctcggcagc
     1621 atggaaggcc gcaagcacat ctacgagaag atcaccgcgc gggccggcct cgacctcaga
     1681 ccggccgcca gctggctgct gctgcgcatc cagcattacg gatcggtgga accggccctg
     1741 ctcgtcgagc gcaccaatgt gccgctcggc gtgatctccg agggcgtccg ccagatcgag
     1801 gagcgcggcc tcgccgcacg cgaaggcctg atgctgctgc tcaccgaccg cggacgcgag
     1861 gcggccgggc ggctctccga cgcgcgccag gaatccctgg cggaactgct gggcgactgg
     1921 tggaccgagg accgccccac cgacctgacc gaaatcgtcc gcgaactgag cgccgaactc
     1981 tgcggatccg acgcggagga gccgcacgac ggcaacgccc gccagcccgt cgcccgcaca
     2041 ccgcaccgga cgccgcggcc gcccggggtg ccgaagtgag ggcggcccgg cagcgggaac
     2101 ccaccgagtg agaaacacgt ttcccgtcca ccggcgacaa ggggctttcc gctgctcaat
     2161 caccccctcc accagcggca ttggcccgga acctaaccgt ccggatcggg catcacccac
     2221 tagatcgtaa aaaagttcga tcaagtccct tgtatgggtg ttaacttgtg aaccggcagt
     2281 cggatgactg ccggtttgta ctgttggagg ctgttatgga agagcagaac gagctctcga
     2341 acgtagagcc ctacgcgccc ccgatgctgg tcgaggtcgg cgagttcagc gaggacacgc
     2401 tgggcttcat cggctggggc aaggacatct tcggccacta cggcggccgc tgaccgtcga
     2461 cggctgactc tcaggagcaa gcagagatga ccggtgctgg gttcgtggtc ctgccggaca
     2521 cggcgtccgc agcagaggcg cgcgcggtgg tgccctgggc ggctccgcgg gtgcactcgc
     2581 atgcgtcggg gcgcccatgg ctggtgggac ggtggctgcc cggagagatc caggtggtca
     2641 ccgcgggccc ggtacgagtg gcggtgatcg gggtctgccc ggtcaccgcc acgcggttgt
     2701 ccgaactcac cgcgcggata aggacggtgt ccgatgtgga caccctcgcg gcggcgctgc
     2761 ccggctcctg tcacgtggtc gcctccgtcg acggccggct gcgcgtccag ggcagcctga
     2821 ccggcctgcg ccgggtgttc cacacccggg tcaacggcct gacggtggcc gccgaccggg
     2881 ccgacgtcct ggccgcgatg accggcgccg gaatcgacga acgcgccctg gccgtacggc
     2941 tggcctgcgg agggctcgtc ccgccggcgc tcggcgaccg gcccctgtgg aagggcgtca
     3001 ccccgctggc gccggaccac tacctgctgt gggacggcga acggacccgg gacgtacggt
     3061 ggtggcaacc gccggccccc gaacagccgc tgtcggccgg ggcacgggcc gtacgggagg
     3121 cgctcacctc cgccctgcag gaccgcggac cggccgaggg ccggctgagc acggacctgt
     3181 ccggcggcat ggactccacc tccctgtgct ttctcgccgc ccgcagcgtc ccggacctcc
     3241 tgacgttccg atggggcgag gccgaggcgg gcaacgacga cgccgccttc gccgcccact
     3301 ccatcgacgc cctcgaccgg gccgaccatg tggtggtgcc gcccgccgaa ctccccgcgc
     3361 tgtacgccga cgcggacgtc ctgatggaca ccgaagagcc ctaccccttc gtccgcaccg
     3421 ccgcgcgcac gcaccacacc gcgcggctgc tcgccgcccg gggatcgcac cgccatctgg
     3481 ccggccacgg cggggacgaa ctcttcaccc cgttctccgg ctatctgcac ggtctcctcc
     3541 ggcgccatcc ggtggccgcg ctccggcacg tccgcggata cgccgcgctc gaacgctggc
     3601 cgctgctgca caccctggcc tcgctggtgc gccccggtga cgaggcgtca tggtggcggg
     3661 cgcaggccga tcacctcacc gacccgccgc tgcgcaaacg ccgccccagc ctgggctggg
     3721 gcctgtggcc gctgcacgcc ccgtcctatg tcaccggcac ggccgtcgcg gaggcccggg
     3781 aggtgctgcg gcacaccgcg gacaccaccc gcccgctctc ccgcgacctc ggccagcacc
     3841 agctgctcct ggcggtgcgc accagcgccc cctggtaccg cctgctggcc cgcccgttcg
     3901 ctgaggccgg tgtgcagctc gactcgccgt tcttcgacga ccgcgtcgtc gaagccgtgg
     3961 cgggcgtccg tgtccatgag cactccggcc cctggcgcta caagccgctg ctggccgagg
     4021 cgatgcgcgg catcgtgccc gaaacggtgc tgggccgctc caccaagggc gaattcagcg
     4081 aggaggccaa ctccggcctg cgccgcaacc tgcccgcgat cctggagctg ttcgacgact
     4141 ccgcgctggc cgcccacggc ctgatcgact ccggcgaact gcgcacccgt ctgctggccc
     4201 cgcaggcgga caacgccatg agcatcgccc tggaaccgct gatcggctgc gaaacctggc
     4261 tgcgcgccgc cacccgaccc acccctgctt ggaggttcga cgcccatgcg tctgcatcct
     4321 gacgtggtct ccaccgacac cgacgacggc accgtcctgc tcaacggacg caccgggcgc
     4381 tactggcagc tcaacgccac cggggcccat gtgctgcgcg ggctcctcga cggcgacagc
     4441 cccgacgaca tcgcggccgg cgtcgcgacc cggcaccgga tagacccgtc ccgggccgag
     4501 cgggacgtca ccaccgtgat cgatcaactg cgcaccgcgg gactggtgat cgcgtgagcc
     4561 tgcccgtcgc gctgtccgag cgacgccgac tgcccctgca ccggcggctc gtaccgctgc
     4621 tggcggtcgg catcgcccgc ctgcttgcca aggccaaacc ggcccggctg cgcaccgtcc
     4681 tcgaattcgc ccgccgcggc gcgtccccgg ccaccgccga ccaggccctc gaggcccgcg
     4741 cagcggtcgt ctcggtcagc ctgcgctgcg ccggtcaggg ctgtctgcaa cgctccatcg
     4801 ccaccgcact gctctgccgc acacgcggcg tctggcccac ctggtgcacg ggcgtgcgca
     4861 cccacccctt cgccgcccac gcctgggtgg aagccgacgg cgagcccgtc ggcgaacccc
     4921 accccaaggg ccacttcaag ccgctgatct ccatacctcc gctgcggagc ggcgagggat
     4981 agccgtcccc ggactcaccc accgagccgc tcctcgcaca cacccagccg ctcctcgaag
     5041 acaccgagcc gcttctcgaa gaagatctcc gcatagatgt cgtcgtggta ccgcgggatc
     5101 tcggtgaagc cgtgccgccg gtaaagcgcg atcgcctcca ccagatccag ccgggtgtcc
     5161 agccggatgc gcccggcacc catccggacc gcggccgact cggcggccgt gagcagtccg
     5221 cccgcaccgc cccggccgcg gtaggggatc cgtacgaaca tctgcttgag ctccgcggtc
     5281 cgctcgtcca gcagccgtac cccggcacag ccggcgacgg catcgccgta ccgggcgatc
     5341 agcagcacgc catgaggcgg cgtcagatgg tcgtccggat actccgccag gccttccgcg
     5401 atctcctcgg gcgtcgcgcg ccgcccctcg tgcagcgcga agtagcggtc ggcgacctcg
     5461 gtgtagtagt cccgcaacag cgcccgggca tcgggcgaac cccaaggctc ggcggagacg
     5521 gtccagggga ggcggagggc ggcggtctga ctcatggcgg cattgtcgcc gcggccgggg
     5581 agcgggacgc aagcgatttc ggcggcgcgg gcggcgacgg acaccgcgcg gcgcccgcca
     5641 ccgccgtacg ctcagccctt cttggggctc gcctgctgta ccacctcgaa ggaccacagc
     5701 gtggacccgg tcgcggccgg cttgggccgc tccccgccct cgccgccgcc ctggtgagca
     5761 gccttcatcg gcccctccat ccaggcctgg aaggattcct cgtcccgcca gcgggtgtag
     5821 acgaggtact gatcggttcc ctccacgggc cgcagcagct cgaaccactc gaagccgtca
     5881 gagctctcaa ccgcgtgtgc gcgggatgcg aagcgcttct ccagggtttc ccgctgttca
     5941 gcagggacag ttaggacgtt gatcttgact acgctcatgt ccccatcttg ccgcacgtgc
     6001 ggcaagcgac gacgagtgag gcgtgaaggc cgccgtaagg cgggcaaggc tcgtaagccc
     6061 cgagaggccg caaccagtgg tgacgactcc gcggcaatca ggacgtgggc gagagagaac
     6121 ggctaccggg tccgggtacc tgccgacatc cgcgaggcgt acgagaaggc gaacaagtag
     6181 acacacggac gtagaatcaa gatatcaagt cgacgaaggg ctccgtggtt tggagccctt
     6241 cgtcgttgcc gcgagtgcat tcaagaatca gcgagacctg agcggtacac gtggtcttgg
     6301 atcactcttc ccagggcata ggctcagggc ggcggtacca ccaccatgcc ttctgcaccg
     6361 aatcagtgat gggcctgtgg ctgtcgccaa tgacaacgtg ttctttgtct tcgacggtca
     6421 gctcctggta gaggctgtca accttgtcaa cgtagcgctt gtaaagcgtt gcaatgcttt
     6481 ctgggagctg acgcagatat ccctcgatgt catcgcggta ttcgagaact tcccggtaga
     6541 agtccaacgg gtaccaacca gatggctccc agttgttctc tgcgcgacgg gatagttttt
     6601 cccatgcccc taggtatgac tcggcaaagc gtgctacttc agccacctca gccgtaactg
     6661 cgccggctcc ctcgccttgt ccgtcctgtg agaggttcgc gaccgcttct gcaaaagagt
     6721 cagacagggg cgttgcgatg gcctgcgcgc ggactacttc cggcaggtgt atcacaggca
     6781 cgtccggcag ctgctcgacg aacgcctcaa ccgctgtgac catgaattct tcgtcgtccg
     6841 gatcgggaag tcgagccctg atcacctctc cttccggagt taccagtgag tgggcgctga
     6901 cggggctctc gtccggcgga tacagaacgg gtgtcccgat ccgctgggca agtgcagcgg
     6961 acaactgggc ttccgagggc tgctgttcca ctgactcctg agcgtaaatg ttcagcgaaa
     7021 gagacacgtt gccctggacg ggagaatagt cgcaggacac cagggcatcc cagtaacgtc
     7081 cctcttggtc gccgtcgggg tcggcaacat ctacttcctt caccgggaca tggagaattg
     7141 ccgcaagcgc ttcagccagg acatctggcc cacagctgtc aacgaggaag agattatacg
     7201 tcatggtgtg taagtcccat tgtaaatggc cagagccttc tcgaccatct gcggattatt
     7261 gacgaaccgt ggcgcatgcg tcagctctgg tacagccgag aggtcaccct tggcttttgc
     7321 gatgcgtgaa agcacgtagt attcgtttct gtccatttcg acaagccccg ggccgcggca
     7381 agggtacacg gtcccatttt ctgggtgaac ggagtattcg cgaccattga ttatgtaggc
     7441 atcacccttc ggggtgaggg cagccttccc ctctgcgatt cctgctatat ccttttcgac
     7501 ttcgctatag aacccgggaa ggatgatggt gttttccttc ttgatgttct tgcccgctcg
     7561 ggctgcccca ccaattgtat gccggtcgtt cggcggcctg agggtttttc cggcggcagg
     7621 accctttacg tcgggtgaaa cttcccatcc gctggccttc ggcgtcccgg aagctccacc
     7681 accgccgccc tcggcattgc gcatcaagcg ccaaccggtc gccgggccga cgggccccgc
     7741 gccagccatg gtcaggcgcg gaccacccaa gttgggtatc gatatctcaa agtcgcgcag
     7801 cgagttcttg aagttaccca ggccgtccag cttcatcttg ccgaaggcgt tcttgaaccc
     7861 acctgcgtca gcgatggctt tggcgccacg cccggctgcg ccgaaagcgc cgccgaggag
     7921 catgccggag gtaccagcgt ccttgacttc agcgaggttg atgccgtgtt ggtcaccaag
     7981 gaggttccgt ccgccctggg ccacgaccac gtctacggtg atggcctcaa tgccgccgat
     8041 cgctgcggtg gccaggacgg tgcctgcgat ttcagcaacc gtagtggaga cggcaatgcc
     8101 ggccgcgcta gacgctgcca ggatctctgc cgtcgctgcg ccagcagcgg cttcactgat
     8161 tccggctgtg aacagtgcaa gggccgttcc cgcaactatg acggctccgg cgatcgccag
     8221 ctcgtgctcg agtttcttcg tcgcctcggc gatctggtcc gcgaacttgt ccagcgcctt
     8281 ggccatgtcc cgcgctgcat cggcaacgtc gtccaggtaa cccttcccgc caccgtggta
     8341 cttgcgccag aaggaggcga aggcatcgat cgacttgccc ttgttgttgt cgatgatgtc
     8401 ttgcgccgac ttgtgggtcg ccgaggtgat gtccttgacg tcgtcagcaa aagttcgcca
     8461 ggcccgtgcg gcttcccgga gttcatcctc atcgccctcc ggccaccaca tgccggtgag
     8521 gtcctggacg atctctttgg ccttgtcgcc ggcgctcaat gcgtaccccc accatggcgc
     8581 ttgaagcccg aggcgttgga gtggtccgtg tcctcgtggt tatcagccat gtccttcatg
     8641 gccttgtgga tgctttccag ccccttcacc agagcgtggg cagcacgctc gattttgtgt
     8701 cgatgtgggc tgtagatgtg cccgaacttc ttcccttgtt cgtcgtcccc ccacggctcc
     8761 ccgagcgcat cgagtgagtg ctttagcttc tccgtcgcct tttccaaggc gacagattct
     8821 ctgtgaaatt ttggcgcttc actcttcagc tggtccgtgt ctacgtcgaa gccagaagcg
     8881 gccacgagtc ccccttaacg ctcatctcag gtccgctaca aacctaccct gcgccactga
     8941 cagtggacct agctggctta cgcccacaac tggttagtcg acttcggtgt gatcgcgcat
     9001 attacgtccg atcagatgta gccaagtcgt ggcttaaagc cgccagcatt gtgtgctgtt
     9061 caactaaatc ggagggtcgg taaagggggt gatgacgcat cgtgggctgg tgattgattc
     9121 ccccaaccga gcggtgattt acgtctgttg aacgcttgct gcaaggcgct tcgacccagg
     9181 gtgccgagaa cttgcgagcg ccatcatcaa ggtgagggct acgccgacag cagctgcccc
     9241 tgtgtgatgc aggctggcgt cggggtgccg tccgaccatg tcggtagacc gctgtcagac
     9301 cgacgatgag tgttgccgac accgctacca gggcgagcag cggtctgatg ggagagcgcc
     9361 ggaggttcct cgtcgatccg tagtcctgcc atggacgctc gggtacgggg tgccggacgc
     9421 gttctcccgc ggctccagca cgttagtggt acatcagagc acccgttgcg gccgcagcag
     9481 ctcgaaccac tcgaagccgt ccgcggagtc caccgttccg gcgcgcgccc cgaaccgctg
     9541 ctccaggacc tcccgctgtt cggcggggac ggtcagcacg ttgatcttca cgatgctcat
     9601 gcgcccatcg tgccgtacgg cgcaaaggag ccgccgacca aggtccaccg tggtgccgga
     9661 cgggtcaccc gtgcagcttc aggcccttgg tgatcttgtc gatggtgttg cgcggcccgt
     9721 acaccgcgag ccccaccaga tcgagatcgc cggcggccac ggcccgcacc gaggcgcggt
     9781 tgtcgtcgtc gttgccggtg cggaacatct cggtggtgta gacggcggtc ggcacggcgc
     9841 ggctgagcgc gcgggcgtgg gtacgggaca gcgcgccgga gtcggcggtg aagcagagca
     9901 ccggttcgcg gaacagcgcc aggtagtcgt tccccgaggc gtcctcgtag cggtgcctgc
     9961 ccatgatgtc gtcggcggaa tgggcgatgc cgctcgccag gaaggcggtg acgttgagct
    10021 tctgccatac ggcgaggtcc tcgcggacga ttacggcgat cttggtttcg aagcgggggc
    10081 cggggccggc ggcgggcgcg gtcgcgaggg cggggggagt cacagcgggg ctggtgatcg
    10141 gcgtagtcat ggcagggagt ctcgtccggc atccggaccg ccgtattgaa cgctggtgcg
    10201 gcgcggcaca ctgggcgcat gaacgggagg cgggacgggg acgccgggga cacccgggag
    10261 catggggaca cccgggagcg cgggggcacc ggtggcggcg actgggcgcg gtactggcgc
    10321 gatccggagc gtcccctgga ggccatgcac gcgcacttcg tccggcatgt gttccacccg
    10381 cacagccatg acgcctactc gttcgccgtc accgaggccg gcgcccagcg cttcacctgc
    10441 cgcggcgccg gtcacaccag cgccgccggc atggtcatgg cgttcaaccc ggacgatccg
    10501 cacgacgggg agtcggccgt cgacctcggc ttcacctacc ggatcatgca catcggcccc
    10561 gacgtggtcc gcgacgttct cgacgatgtc accggcggcc gtggcagcat gccgctcttc
    10621 gcccagccgg tggtcgacga tccggtgctg gcgcgggcgc tgcgcagact gcaccccgcg
    10681 ctggtcgggg ccgccgaccc gctcgtacgg gaggaacggc tcggcgccgc cgtcgaggcc
    10741 atggtgcggc gcaatgccag caggggtgcc gcccagtccg ggccccggga gctgacgggc
    10801 ggtgcgcaga cgagggcggc ccggcgggta cgcgacctcc tgagggccgc ctacgaccag
    10861 ccgctcaccg cccaggacct cgccgacgcc gccggatgca gccgcttcgc gctctaccgg
    10921 gcgttccgca ccgcgtacgg catgtccccc agcgactacc agcggctgct ccgcctgcgc
    10981 cacgcccgca cgctgctcat cggcggccgc cccgcctccg aggcggccac cgaggcgggc
    11041 ttcgccgacc aggcgcactt ccaccgctgg ttcgtccgct gcttcggcat cacaccgggg
    11101 gcgttccggc gggccgcggc ggtgacgcag tgccccggcc cggcgaggtc atgacccgct
    11161 gacgtcccgc cggcgccgcc tgcgccgccg caccgtcagc gcgatcacca ccagcagcag
    11221 caccccgccc accacaagaa cccagacggg tacgccgccc accttcatca gcacatccgt
    11281 gtagtggacc cgccgatacg gcgtatcggc ggccgcccgc cggagctcat gatcgccgct
    11341 gatccgctcc ggatgcggaa agcgctggtc gatggcggtc agaaaggccc cgccggtacc
    11401 ggcgagggcg ctcaccggcg tccccttggt cttgatccgg cccgcgaaga agacctccgg
    11461 cgccgaaccg ccgatggcgc cgcgcggctc catccggtgc ggtgcgagca catacagacc
    11521 cagcgactgc tgcgtcgtgg cgagccggga caaccgcatc gggtagacca ggcggtcgct
    11581 ggcgaaggac agccgcagcg ggtcgagggt gccgttcagg aagccgtact tctgggcggg
    11641 ggccagccgg atcgcgacgt attcccagtg ctgggccaca tacggacgca gtccggtagc
    11701 gagcgaggac ggcagccgga agccgtggga cgtcagccag ccgcgcaggg cgtcggggtc
    11761 ggtggcggtc agccgggcca catcgaaggg gcccaggcgc tcccggccga cgaggccgac
    11821 ccccgggccg gcggcgccgg gtgcgggggc cgcggccgtg tccccgtcgc tccaccggaa
    11881 cggccagtcg ccgccgtgcg gccagaagta ggagcggtcc ttctcgaccg gcttcgtgag
    11941 cgaggcaagc tcgtcgaaca gcgccctgtc gcccagcttc accgtggcgc ggtgcgggac
    12001 cggcatgatc caggcggcat ccggggcgtc cccgtgcacc gtcaggctca tcacgatctg
    12061 ctcggtcctg ccgtcccagt gcaccgccga ggtctcccgg tccaccgaca tggtggtctt
    12121 cgggtcgacg accatcgcac cgcagccgca ggcgtacgcc ggcctggcca gcgccaccag
    12181 ctgcatggcc agcagcatca gcaccaccag cagagcctgc cgccgccgga tgctcccgac
    12241 tctccgagcc gaagccgcgc ccatccccgt cccccgatcg ccacgctgcc gatcacggtg
    12301 atcggcagcg tcacagacgg gcgcggcggt gcctgtggtt ccccttgcgg gcgtgttcct
    12361 caccggccgg agccggtgag gccgcccccc gggggtggcc ccaagtggcg tctcaggccg
    12421 tgtcaggccg tgtcaggccg ccgatgcggc ttcggcgccg cgggacgcgc ggacgatctc
    12481 gcgggcctcc gcctcggtct cgacggccgg cggcgaaccg ggcagcggcc tgcgcgcact
    12541 ctcggacatc cgccatacgg cgatcccgcc gatcacggcc gccgccatca tgtagtaggc
    12601 gggcatcatc ttgttgccgg tcgccccgat gagcgcggtg accaccaggg gagtcgtacc
    12661 gccgaacagc gagaccgaga tgttgaagcc gatcgacagc gacccgtagc gcaccttggt
    12721 cgggaagagc gcgggcagcg cggacggcat cgccgcggtg aagcacacca gcagcaggcc
    12781 cagcgcaccc atgcccagcg cgatggcggc cagcgagccc tggcggatga gcagcagcgc
    12841 cggaacggac agcaccagga agccggcgca gcccgccgcg atgaccgggc ggcggccgaa
    12901 gcggtcggac agcctgcccg cgaagggctg cacgcccatc atcacgacca tcacgccgag
    12961 cacgaccatc agcccgtgcg tctcgtcgta cttcagctcc gaggtcagat agctcggcat
    13021 gtacgacagc agcatgtagt cggtgacgtt gaagaccagg accagcccga cgcacagcag
    13081 catcgcccgc cactgaccga agaccatctc gcggacgccg atccgcttct cggcctcgcg
    13141 gcgctccttc tccttggtgc gcgcctcctt ctccagccgg gcgaaggccg gggtctcctc
    13201 gagacgcatc cgcaggtaga ggccgatgat gcccatcggg cccgcgatca ggaacggaat
    13261 ccgccagccc cacgcgtgca gatcgtgggt ggacagcagc gcggtcatca gcgtgaccag
    13321 gccggcgccg ccgacgtaac cggccagcgt gccgaactcc agccagctgc cgaggaaacc
    13381 gcgcttcttg tcgggcgcgt actcggcgat gaaggtggac gcgccaccgt actcaccacc
    13441 ggtggagaag ccctgcacca ggcgcgcgac cagcagcaga atcggcgcac cgacgccgat
    13501 ggtggcgtag gaggggatca ggccgatggc gaaggtgccc gccgccatca tgatcatggt
    13561 gatcgcgagg accttctgcc gcccgatccg gtcgccgagc ggcccgaaga ccatgccgcc
    13621 gatcgggcgg accaggaacg ccgccgcgaa cgcaccgaag gtcgacagca gctgtgcagt
    13681 ggggttgccg gacgggaaga agacatgccc gagggtgacg gcgatgtagc tgtagacgcc
    13741 gaagtcgaac cactccatcg cattgccgag ggcggccgcg gacaccgctc gcctgaccat
    13801 cgcggggtcg acgacggtga cctcgtccga cgtccgcttc tccaggtcgg gtgcggcatc
    13861 ggtacggctg gggctgcggc cgtgggtggg ggccccggat gcgacggggg actgcgtcgg
    13921 cacgtgttcg ctcgcctgcg ctctcttgga cgactgcatg acatcgcccg ccatggagtg
    13981 acgggcaaag gtcgaccata ggggcagaac gggtcatcac ggacagtgtg cggatgaccg
    14041 cgcgatcggt cgtctatccg ctccttgctg ggcaaacgcg tttccttgcg gaatttcgcg
    14101 ggactttcgt ctgtgatcca tatcgcggta attcactgca accctcacgc tctgtgacgc
    14161 gggggagtgc cggtccctgt ggcgcgcgcc acgcaggaaa acggcgcgac ggcccacttc
    14221 gccgccgcgc cgatggatcg tcgcgtccct caaggatccg gcatccgggc acgtcccgcc
    14281 acttgggtgc ggtgtgtccc cggggcccgg ccggtcagcg gaacccgcgg ccgccgcgcc
    14341 cctcgtcgtc ccgtgcgcgg gcccaacccc gttgacgcca gggcgtgttc gctccgttac
    14401 gatcacctcc aagcggcttc cccgtccccg aagggtccgg cggagccgat ccagcgcgtg
    14461 agggagaacg tcatgggcag cacacctgac ctgaacggcg ctcaccggcg cacgtccggc
    14521 caccggaacg gaacccggtg aagacccgcc ggctcggcag cggcgagcac tccgcacccg
    14581 tgtccgcgat cggtctcggc tgtatgggga tgtccgtcgc gtacggaccc gccgacgcgg
    14641 acgaggcccg gcgcacgctc gaccgggccg ccgagctggg cgtcaccttc ctcgacacgg
    14701 cggacgccta cggccgcggc gccaacgagg agctcatcgg ccactggatg cgcgaccggg
    14761 gccgccgcgc cgacgtcttc ctcgccacga aattcgggct gcggcacgac gccgccaccg
    14821 ggcgcgtcga caccgtggac acctcaccgc agtacgtacc ggctgcctgc gacgcctcgc
    14881 tccggcgcct cggcgtcgac cgcatcgacc tctactacgc ccatcgccgc gaccccgcca
    14941 cccccgtcga ggacaccgtg ggcgccatgg cggaactggt ctcggccgga aaggtggcac
    15001 atctcggcct ctccgaggtg agccccgcga cgctgcgtgc cgcgcacgcc gtacatccca
    15061 tcgccgccgt ccagttggag tactccctct tcacccggga cgtggtggag ggcgagatgc
    15121 tcgccacctg ccgcgagctg ggcatctccg tcgtggcgta ctcacccctg ggccgcggca
    15181 tgctcgccgg ggcgctcgcc tcccgggacg agctcaccga ggaggacaac cgccgccgct
    15241 ggccccgctt ttcggcggac aacatcggcc gcaacctcgc cctcgtacac gaggtccggc
    15301 gcctcgccgc ggagatcggc gtcacgcccg cgcaggcggc actcggctgg ctgctggccc
    15361 agggggacga catcgtgccg atcccgggga ccaaacgggt gcgctacgcc gaggagaacg
    15421 ccgcggccgc cgggacgggc ctcacacccg agcaggccga gcggctgcgg gcggcggtcc
    15481 ccggcgcggc cgtggccggc gcacgctacc cggagcaggc gctgcgccgt ctgggccact
    15541 gaccgggccg ggcaccggaa ggccgtaccc gggcccgctc ccgggacgcc tcagggcatc
    15601 cacgcctcgt acgacagcac ctccccggac ctgatcctga cgtcggggag gttcttcgtg
    15661 aacgtgatct cgctgcccag gagttgtccg gtccggggat cgaggatcac catctggcgg
    15721 gtggcgttcc ggccgccgtc cgggccgtcg tagacatatg cctgaccgcg gcggcccagc
    15781 cggtcggtga ccgcacccgc cggacgcagg ccctccgcat ccgccagcac ccggacgatg
    15841 gccgccgtct cccgcggccc cggtgtccat tcctgccgca gggacgagag cgcgagcagc
    15901 agctgcggcg tccgggcgcc tgccgggccc gccgtgtcgc ctcttccgcc ccctccgccc
    15961 ccgtagagcg tggcgagccg gtcgcgcagt gcgccggggt cggtcggcgg cttcgtgcgg
    16021 gcggcgaggc ggcgctgccg ctgcccgtcc gccgaacccg ccggataggt cttgcggtgc
    16081 agcactttgc cgtcattgac ggtgtgccag ctgccgcccg tatcgttgat caccgggcgg
    16141 ccggggtgcc gcgggtcggt ggccacgacc agttcggagc cgctgccgtc cgcgcgccac
    16201 cgggtgatgc gttcctcggg cacggtgacc ggcggcgcgg catcggggcc cgtctccatg
    16261 ctcagatacc agctctgcag atggctgccc cggtgcggcc cgtccgcggc gccggccgtc
    16321 cgtgccctgg cctcggcccg gcgggcgagc tcggccagcg ggacggcggg ggcgtcggcg
    16381 cgcggggcga gtgcgacggg catcgcaacg gccttgccgg acccggcatc ggagaaggtg
    16441 aaggcgagcg cggcgccgag ggcgagcacg gcggcctcgg ccctgagcac caggcgccgc
    16501 cgggcccgct tcgtccgcgc gctgtgcagc aggcggttca ggccgcgttc ggcgcgggcg
    16561 tgcagcgggc cgtcccgcca ggggccgtcg tcggcccgtg cgggatcggc tgcgcgcagc
    16621 agatccagtt cgtcacccat
//
