LOCUS       reptomyces_RBGC_427116 16617 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_427116
VERSION     Streptomyces_RBGC_427116
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_900187925.1
  ORGANISM  GCF_900187925.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..789)
                     /protein_domains="PF18029"
                     /protein_domains="PF18029"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311600"
                     /pseudo=False
                     /translation="MSGSDERRNVSAQGAPCWVNLMVADLAVARAFYGEVLGWKFRSSS
                     LDDQFLVATAGGHPVAGIGARRPGLAPASVWTPYFAVRDADVTAARIRERGATVAVGPM
                     AMGDGRVGLAADRDGATFGFWEGYTLAWSPGEGQAPARIDLQTRDVFDAAVFYGEVFGW
                     AEGEDVDVAYRKDHVLVQLGGRVILSLRGGGVQTSSLAHLRPRWLVNFAVDDVERAVAA
                     ATSAGGVRPEPSPATWAPSGFSRTLQDPDGGLFTLSQRDV*"
     CDS             complement(953..1551)
                     /protein_domains="PF03358"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311601"
                     /pseudo=False
                     /translation="MRALALVCTLNSSPAPSSSQHLAEQVMAQFARHDVQGEIVRVADH
                     DVRPGIGTDMGDGDAWPAIREKVLAADILLIATPIWLGHPSSVCQRVLERLNAESSETD
                     DQGRPHTYGKVAVVAVVGNEDGAHKVSADIFQGLNDVGFSLAPGAVTYWVGEAMQGTDY
                     QDLDETPEAVATTTEALAANATHLARLLTGGPYPAS*"
     CDS             complement(1642..3116)
                     /protein_domains="PF01276"
                     /protein_domains="PF03711"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311602"
                     /pseudo=False
                     /translation="MTMDHHEAPVLEALAAYRDRDELGFSPPGHKQARGASPAVRAVLG
                     DAVFFGDLLATGGLDDRQEKSSVLRRAEQLMADAVHAEHTFFSTCGSSLSVKAAMLSVA
                     APHQKLLVGRDAHKSVIAGLILSGIEPVWLDPQWDAERHLAHPPAPETLERAFADHPDA
                     TGALVTSPTPYGTAADLRAMADVCHRRGKPLIVDEAWGAHLPFHPDLPSWAMDAGADVC
                     VTSIHKMGSGLEQGSVFHLQGDLIDPDTLASRADLLGTTSPSVLLYAGIDGWRRQMALE
                     GHGLLSQALDLVATVRRRIEEIEGMHVNGPDDFCGPGGSAEFDPLPVIIDISALDTTGY
                     RAADWLRRHHHIDMHLVDHRRISAQFTHADDSDTAERLIAALLDLARNAHTLRPAPAVH
                     VPAPAELRPDQTCLPRDAFFAETEDVPAAQAVGRVAAEMLTPYPPGIPAVLPGERITEP
                     LLRYLRSGVEAGMNVPDPADPTLHTIRVRAEED*"
     CDS             complement(3171..4057)
                     /protein_domains="PF13561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311603"
                     /pseudo=False
                     /translation="MPGSEQPQDPHTLHPRPDFPQQDQAHPGWTGPMDPPPDHGEDSYR
                     GSGLLDGRKAVITGGDSGIGRAVALAFAREGADVLLTHLPEEEQEAHETVRLVEQAGRE
                     AVPVLCDIRDEKQCRSLVERAVSQFGRIDVLVNNAAYQMSQPDGISAISTEQFDRVVRT
                     NLYGMFWLCKSALPHIPAGGSIINTTSVQAYKPSPHLLDYAMTKGAIVTFTQGLAQMLA
                     SDGIRVNAVAPGPVWTPLIPATLPDTAEFGKQSPLGRPAQPAEMAPAYVFLASANASFI
                     TGEIMNATGGTPLP*"
     CDS             complement(4252..5435)
                     /protein_domains="PF08240"
                     /protein_domains="PF13823"
                     /protein_domains="PF00107"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311604"
                     /pseudo=False
                     /translation="VRALTYQGKRDVRVETVPDPRVQDPTDIIVRITSTGICGSDLHLC
                     EVLGPYLDPGDILGHEPMGVVEEVGREVTAFAAGDRVVIPFNVSCGHCYMCGQGLHSQC
                     ETTQVRERGMGASLFGFTKLYGQVPGGQAEYLRVPFGNDLPIKVPHGPPDDRFVFLSDV
                     LPTAWQAVEYADIPPGGSVTVLGLGPIGAMAARIALHRGAGLVIGVDLVPERLERASRH
                     GATCLDLRRYGKNLGDAVRDLTDGRGADAVIDAVGMEAHGSPVAKAAHTAVGLLPDALA
                     QRLMETAGIDRLAALHTAIDLVRRGGTISLSGVYGGSADPMPMLTLFDKQIQLRMGQAN
                     VKRWVDDILPLLTDDDPLGVDSFATHHLPLEEGPQAYETFREKADGMIKTLLVP*"
     CDS             5701..5846
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MVSPCPASTLRPPASWPATASPLPRESPSPGGAVPLPPRGGGGSQ
                     TVA"
     CDS             6117..6355
                     /protein_domains="PF11160"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311605"
                     /pseudo=False
                     /translation="MAKRRKDLSAGDDVSWRSHGHRVEGSVTRKVDGRTEAAGRKVDAS
                     KEEPQYEVRSDKTGKKAVHRPESLKRRKDNGAGS*"
     CDS             6353..6783
                     /protein_domains="PF11338"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311606"
                     /pseudo=False
                     /translation="MSKGSEQERQKTLDHFSDAVNMTARELEDWLATDQSREVGQKDGG
                     ESTGHASGRHIVKLLRTRKGELNDDDLAHMRKVTGYVRRHLAQRPGGNASDTPWRYSLM
                     NWGHDPEKQPPRHQARPFPPHQLGRGRRGLRITGQVGTA*"
     CDS             6873..7414
                     /protein_domains="PF00857"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311607"
                     /pseudo=False
                     /translation="MRKSALIVVDMINTYDHPDADLLVPSVRDALPHISRLLTRARARA
                     EGVPVIYANDNFGEWRSHHGEIIEKSLAGDHADLVEAVLPDAASLFVVKARHSIFYETP
                     MSYLLSQLRASHIVLSGQVTEQCVLYSALDAHIRHLQVTIPEDAVAHIHHDLADAALRM
                     MERNMGATITKANDVTF*"
     CDS             7402..7514
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MSPSETGSETASHHQKEDAGPGQPPSSMSEHRNEEMA"
     CDS             complement(7574..7821)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311608"
                     /pseudo=False
                     /translation="MTLSVTFSLVAGIVRVSSDSSHEPDQHVPVSHAPLVPSLGENGTA
                     LLVGHHDTRTGPAIFLNLNALRRGDKVDGETGRQICG*"
     CDS             complement(8086..9428)
                     /protein_domains="PF00005"
                     /protein_domains="PF08402"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311609"
                     /pseudo=False
                     /translation="MSRAIELRKVNKVFGSSHAVRNLSLTVARGEFLVLLGPSGCGKST
                     VLRLIAGLEDITDGELFLGSDFANHTLPSERDMAMVFQNFALYPSMTARENIGFPLRLQ
                     DSQVDPDPAVTATARMLAIEDLLDRRPGQLSGGERQRVAMGRAISRRPSIFLMDEPLSS
                     LDAKLRGQLRAEIARLTQDLGVTTVYVTHDQAEAMSLGDRVAVMRDGALQQVSPPRDLY
                     ARPANVFVAAFVGTPRINLLDGVVLAPLDGPMTLELGRQRLVLPEPLSVDHQLLRIQQG
                     RRVIVGLRSEAVRMAPRSQARPSEAALTGIVEHIEYQGHEAFVHLNTGSRPAFVPELEA
                     SRFVPDGRSPRRPKKQGGTRMADWLTALLHGGAAVSRGARAGSGSPTILHERRTTVASD
                     LVLRIGPRERAQVGAQVPLLVDLRQLYVFDHAGSRICPAPDAPPGLDP*"
     CDS             complement(9622..13892)
                     /protein_domains="PF07705"
                     /protein_domains="PF00754"
                     /protein_domains="PF00754"
                     /protein_domains="PF00754"
                     /protein_domains="PF07705"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311610"
                     /pseudo=False
                     /translation="MPPSPASRWKWRTAAAALASTVMVLGLPTLGAQAAGGPNAAADAP
                     AKAGSVKGRHVAANISDGDADTYWQAGKKSAQWVQTDLGQAKRVREVVLRLPAHWETRK
                     QTFALQGSADGKSFATLKPSAQYVFSPGNGNTVKVAVPATLARYVRAEFSANSAAGTAQ
                     LAELQVLTTTAATPNLAQGKTFSASGHADVYGAGNVGDGNRNTYWESKNNALPQWVQVD
                     LGSSVKVNQVTLRLPGGWPERSQTLKIQGSTDNQNFTDLTQSKAYAFNNGNDQAASISL
                     DATTTRYVRVLITANTGWPAGQLSELEVYGPAAGDTEPPTAPSGLAFTEPGDGQIKLSW
                     KAATDDTGVTGYDVYANGQLRASLPSSALTYTDTQPGDANVTYFVRAKDAAGNTSSNSN
                     SVTRKGAGGDTQAPTAPGNLSFRQSGGEVELTWQASDDNVGVTAYDIYANDERVDSVAG
                     DVTSFAHRPTASSTVTYHVRAKDAAGNESAPSNSVTRRGSGGGADLAQGKPIEASSSHD
                     TYVAKNANDGLTSTYWEGGGGSYPTTLTTKLGSEADLSQVVVKLNPDAAWSSRTQNIQV
                     LGRGQGATAFTNLVAAKDYAFSPADGNTVTIPVSGSAADLQLKFTKNTGAPGAQVAEVQ
                     VIGTPAANPDLQVTGITHAPAAPVESDPITLTAAVANSGSKEAAATTLDFTLGGEKVGS
                     ADVPALAAGASKNVTARIDAQAEGSYQVGAEVDPANKVVEQNEGNNAFTRPAALVVKPV
                     DSSDLLAAPVSWAPSSPAAGEEVKFSVAIKNQGTTDSASGNHDVSLVIQDDKGETVKTL
                     NASHNGVITAGRTTAPVALGAWTAGNGKYTVKTVIADDANELPVKRANNTTSQSLFVGR
                     GASMPYDMYEAEDGVLGGGAKTVGPNRTIGDIAGEASGRKAVTLTGTGQYVEWTTRAAT
                     NTLVTRFSMPDGPDSTLNVYVDGEFLKTIDLTPKYAWLYGNEAAPSNSPGAGAPRHIYD
                     EANLQLGKTVPAGSKIRLQKDAGNSANYAIDFINTELATAAANPDPAAYTVPAGFSHQD
                     VQNALDKVRMDSTGKLVGVFLPAGDYETSSKFQVYGKAVQVVGAGPWFTRFHAPSSQEN
                     TDIGFRADNTAKGSSFSGFAYFGNYVSRIDGPGKVFDFANVSDITIDNIWNEHMVCLYW
                     GANTDNVTIKNSRIRNMFADGLNMTNGSTDNHVVNNDARATGDDSFALFSAIDAGGADM
                     KNNVYENLTSTLTWRAAGLAVYGGYNNTFRNIRIADTLVYSGITISSLDFGYPMNGFGT
                     EPTTIENVSLERTGGHFWNGQVFPAIWAFSASKVFQGIRVNDVDIEDSTYGGVMFQTNY
                     VGGQPQFPVKDTVFSDISITNSKKSGDEFDAKSGFGIWANEMPEPGQGPAVGEVTFRDL
                     RMSGNAEDVRNKTSTFKINIE*"
     CDS             complement(14360..14826)
                     /protein_domains="PF13673"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311611"
                     /pseudo=False
                     /translation="MNTPDSETFTVRAVRAHEAAAIASIDPIAAHGSPPRRAAVARWCR
                     EGLALVAEDASGLLGYGVREYTFFDQGFITMLMVAPRARGRGVGRSLLDAMANSCATPK
                     LFTSVNASNQPMERLLLSAGWHAVGLLHGLDEGDPEVFYLRPALDGSAPLL*"
     CDS             complement(15014..16617)
                     /protein_domains="PF00128"
                     /protein_domains="PF11941"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_8311612"
                     /pseudo=False
                     /translation="VAAPLPLRSDDWWRDAVIYQIYPRSFADGNGDGTGDLSGVRAKLP
                     YLVELGVDAVWFTPWYVSPLVDGGYDVADYRTIDPAFGTLGEAEKLIAEARELGLRTIV
                     DIVPNHVSDQHHWFRAALAAGPGSPERELFHFRPGRGADGELPPNDWPSEFSGTTWTRV
                     PDGEWYLHLFTPEQPDLNWAHPEVRREHEEILRFWFQRGVAGVRIDSAALLAKDPDLPD
                     FVKGVDPHPYIDQDELHGIYRSWRKIADEYEGVFVGEVWLPDAERFARYLRPDELHTAF
                     NFNFLACQWDAACLRRAIDDTLAEHEPVGAPATWVLCNHDVTRTVTRYGREDTGFDFAT
                     KAFGTPTDLDLGTRRARAAALLTLALPGSVYLYQGEELGLPEADIPRDRIQDPMHFRSG
                     GADPGRDGCRVPMPWAADEPHYGFGADREPWLPQPGDWSDYAADRQAGEPGSMLALYRE
                     ALSLRRSENGFGDGPLTWKPGPDGVLHFSRPGGLICLVNLSAKAVELPAHRARLLSSGP
                     LDGEGRLPQDTTVWLRA*"
ORIGIN
        1 tcatacatcg cgttgggaga gcgtgaacag gccaccgtcc gggtcctgca gggtccgcga
       61 gaaccccgaa ggcgcccaag tggccggaga aggctcgggc ctgacgcctc cggcgctcgt
      121 ggcggcggct acagcccgct cgacatcatc aacagcgaag ttcaccagcc agcgcggacg
      181 cagatgagcc agcgaagacg tctgcacacc gccgccccgc agagagagaa tcacccggcc
      241 cccgagctgc accagaacat ggtccttccg gtacgcgacg tcgacgtcct caccctccgc
      301 ccagccgaac acctccccgt agaacaccgc cgcgtcgaac acgtcacggg tctgcagatc
      361 gatccgggca ggcgcctgcc cctcccccgg cgaccaagcc agcgtgtagc cctcccagaa
      421 accgaacgtt gccccgtccc ggtccgccgc cagacccacc cgcccgtcgc ccatcgccat
      481 cgggcccacc gcgaccgtgg caccgcgctc acgaatcctc gccgccgtca cgtcggcgtc
      541 ccgcaccgcg aagtacggtg tccacacgga agccggtgcg aggccgggcc tccgggcccc
      601 gatccccgcc accggatggc cgccggccgt cgcaaccagg aactgatcgt ccagggaact
      661 cgagcggaac ttccagccga ggacctcgcc gtagaacgcg cgggccaccg ccaggtcagc
      721 gaccatcagg ttgacccagc agggagcgcc ctgcgccgac acgttccgcc gctcatccga
      781 cccggacatc cgctcgctcc tccaagacct tcaccgtgcc caagacccca cacccaccca
      841 cggccgactg gactcccctg tcaatgattc cagaacgagc ctcccgaacc gccggacgta
      901 gcagctcaaa ccggagcgga tcccccggct ccgtggccga gggcagcgtc gtcaggaagc
      961 cgggtagggg ccgccggtga gcagacgggc caagtgggtg gcgttggccg cgagggcctc
     1021 ggtggttgtc gcgacagcct ctggggtctc gtccagatcc tggtagtcgg tgccctgcat
     1081 ggcttcgccg acccagtacg tgaccgctcc gggcgcgagc gagaaaccga cgtcgttcag
     1141 tccctggaag atgtcggcgc tcaccttgtg cgcgccgtcc tcgttgccga cgacggccac
     1201 gacggcgacc ttgccgtagg tgtgcgggcg tccttggtcg tcggtctccg acgattcggc
     1261 gttgaggcgc tccaggaccc gctggcagac gctggagggg tggccgagcc agatcggcgt
     1321 ggcgatgagc aggatgtcgg cggccagaac cttctcccgg atggcgggcc aggcgtcgcc
     1381 gtcgcccatg tccgtcccga tccccgggcg tacgtcgtgg tcggcgaccc ggacgatctc
     1441 tccctgtacg tcatggcgtg cgaactgggc catgacctgc tcggcgaggt gctggctgct
     1501 ggagggggcg ggcgaggagt tcagagtgca gacgagagcg agggcacgca tggctggggt
     1561 ctccttttcg ttggggcgag ggtcctggac ggaccttgtc gggtacggcg tcctggcccg
     1621 gagctgccgg tgggaggtgg tcagtcctct tcggcgcgga cccggatggt gtgcagggtg
     1681 ggatcggccg ggtcgggaac gttcatgccg gcctccacgc cggaacgcag gtagcgcagg
     1741 aggggctcgg tgatccgctc gccgggcagc acggccggaa tgccgggagg gtagggcgtc
     1801 agcatctcgg cggcgacgcg gcccacggcc tgcgcagcgg gaacatcctc cgtctcggcg
     1861 aagaaggcat cgcgcggcag acacgtctga tcggggcgga gttcggccgg tgcgggcacg
     1921 tgcacggcgg gggcgggacg gagcgtatgc gcgttacggg ccaggtcgag cagggctgcg
     1981 atcaggcgct cagcggtatc ggagtcgtcg gcgtgggtga actgggcgct gatccgccgg
     2041 tggtccacga ggtgcatgtc gatgtggtgg tgccgacgca gccagtcggc agcgcggtag
     2101 ccggtggtgt caagggcgga gatatcgatg atcacgggca aggggtcgaa ctccgctgag
     2161 ccaccaggcc cgcagaagtc gtccggcccg ttgacgtgca tcccctcgat ctcttcgatg
     2221 cggcggcgca ccgtcgccac gaggtccagg gcttgggaga gcaagccgtg tccttcgagg
     2281 gccatctgcc ggcgccagcc gtcgattcct gcgtagagca gcacggacgg gctggtggtg
     2341 ccaaggaggt cggcccgtga ggccagggtg tcggggtcga tcaggtcgcc ctggaggtgg
     2401 aagacggagc cttgctccag gccgctgccc atcttgtgga tgctggtcac gcagacatcg
     2461 gcgcccgcgt ccatggccca ggacggcagg tcggggtgga agggcaggtg ggctccccac
     2521 gcctcgtcca cgatgagcgg tttgccgcgc cggtggcaga cgtcggccat cgcgcgcagg
     2581 tccgccgccg tgccgtaggg ggtggggctg gtaacgaggg cacccgtcgc atcgggatgg
     2641 tccgcgaagg ccctttccag ggtctcgggc gcgggcgggt gggcgaggtg ccgctccgcg
     2701 tcccactggg gatccagcca cacaggctcg atcccggaca gaatgaggcc ggcgatgacc
     2761 gacttgtggg catccctgcc gaccagcagc ttctgatggg gtgcggcgac gctgagcatc
     2821 gccgccttga ccgacagaga gctgccgcag gtggagaaga aggtgtgctc cgcatggacg
     2881 gcgtccgcca tcagctgttc agctcgccgc agaacggagg acttctcctg acggtcgtcc
     2941 agccctcccg tggcgaggag gtccccgaag aacactgcgt cgcccagcac ggcacgcacc
     3001 gctggagagg cacctcgtgc ctgcttgtgg ccgggcggtg aaaagcccag ctcgtcccgg
     3061 tcccggtagg cagcaagggc ctcgagaacg ggcgcctcat gatgatccat ggtcattttt
     3121 ggtacacctt tccgcacgac tctaggtctg accaggtgtt ttcccggtac taaggaagcg
     3181 gtgtaccgcc ggtggcgttc atgatctcgc cggtgatgaa cgaggcgttc gcggaggcga
     3241 ggaacacata ggcgggtgcc atctccgcgg gctgggcggg ccggccgagc gggctctgct
     3301 tcccgaactc ggcggtgtca gggagggtcg ccgggatgag gggggtccag acagggccgg
     3361 gggcgacggc gttgacgcgg atgccgtcgg aggccagcat ctgggccagg ccctgggtga
     3421 aggtgacgat cgctcccttg gtcatggcgt agtcgagcag gtgcgggctc ggcttgtagg
     3481 cctgaaccga tgtggtgttg atgatcgagc cgcccgccgg aatgtgcggc agcgcgctct
     3541 tgcagagcca gaacatgccg tagaggttgg tgcgcaccac gcggtcgaac tgctcggtgg
     3601 agatcgcgga gatgccgtcg ggctgcgaca tctggtaggc cgcgttgttg accagcacgt
     3661 cgatgcggcc gaactgggac acggcgcgtt cgacgagtga gcggcactgc ttctcgtccc
     3721 ggatatcgca gagcacgggg accgcctcgc gtccggcctg ttcgaccagg cggacggtct
     3781 cgtgcgcctc ctgttcctcc tcgggcaagt gggtcagcag gacgtctgcg ccctcacgcg
     3841 cgaaggccag cgccaccgca cggccgatgc cggaatcacc cccggtgatc acggctttcc
     3901 ggccgtcgag caggccggag ccgcggtagg agtcctcgcc atgatccggc ggggggtcca
     3961 tggggccggt ccagcccggg tgcgcctggt cctgctgagg aaagtcgggg cggggatgga
     4021 gcgtatgggg gtcctgcggc tgttcactgc ctggcatggc tcttccttct ggtcgtggcg
     4081 gaagtctggt gctccggaca ccgccgcagc ccgtgccgca ccggtgaaca ggttctctgc
     4141 ggacagcgcg actggctgac tggggccgct cagccgagcc ttcggccctt ccaacagtgc
     4201 ggtggtagcg ccccgggcgg tgccaacgcc gcgcagcggg actcatgggc tcaggggacg
     4261 agcaaggttt tgatcatgcc atcggccttc tcccggaacg tttcgtaggc ctggggtccc
     4321 tcttcgagcg gcaggtggtg ggtggcgaag gagtccacgc cgagcgggtc gtcgtcggtg
     4381 agcaggggca ggatgtcgtc gacccagcgt ttgacgttgg cctggcccat acggagctgg
     4441 atctgcttgt cgaacagagt gagcatcggc atcgggtcgg cggagccgcc gtaaacgccg
     4501 gagagggaga tcgttccgcc ccggcgcacc aggtcgatcg ccgtgtgcag tgcggcgagg
     4561 cggtcgatgc ccgctgtctc catcaggcgc tgggcgagtg cgtcgggcag cagcccgacc
     4621 gctgtgtgcg ccgccttcgc cacgggcgag ccatgggcct ccatgcccac ggcgtcgatc
     4681 accgcgtcgg cgccgcgtcc gtccgtgagg tcgcggacgg cgtccccgag gttcttgccg
     4741 tagcggcgca ggtcgaggca ggtggccccg tgcctgctcg cccgttcgag acgttcgggg
     4801 accaagtcca cgccgatgac gaggccggcg ccccggtgga gcgcgatcct cgcggccatg
     4861 gcgccgatcg gcccgaggcc gagcacggtg acgctgccgc cgggcgggat gtccgcgtac
     4921 tccacggcct gccaggcggt gggcaggacg tcggagagaa agacgaaccg gtcgtccggg
     4981 gggccgtgcg ggaccttgat gggcaggtcg ttgccgaagg ggacccgcag gtactccgcc
     5041 tgtccgccgg gcacctgccc gtaaagcttg gtgaacccga acagggacgc tcccataccg
     5101 cgctcgcgca cctgggtcgt ctcgcactgc gagtgcaggc cctgcccgca catgtagcag
     5161 tggccgcagg acacgttgaa ggggatcaca acccggtccc ccgcggcgaa ggcggtcacc
     5221 tcgcggccga cctcctccac gacccccatc ggttcgtggc ccagaatgtc gcccggatcg
     5281 aggtagggcc cgagcacctc gcacaggtga agatcggagc cgcaaatccc cgtggacgtg
     5341 atcctgacga tgatgtccgt cggatcctgg acacgcggat ccgggacagt ctccacccgg
     5401 acgtcccgct ttccctgata ggtcaatgcg cgcacggccc gctcccttcc ctcgctggta
     5461 ctcgtggacg agtgcgccgg gttcccatga gacacctgat gaaacacgca gaaagatcgc
     5521 ggcgagccgt tgaaccggca tctactcctc tgtggagcct ccgccctggt gtcacccgct
     5581 cagcctgcgg aaggcccatc cgctccttcg cagctacggg tggggcctcg cccagccgcg
     5641 gggcgccacc gcgagccgcg acaagcccgc acgagaccgc tgccgtcctc tgcaccaggc
     5701 tggtctcccc ctgcccggcc tcgaccctca gaccgcccgc atcctggccc gctacggcat
     5761 cacccctgcc gcgggagtct ccgtcgcccg ggggtgctgt gccgttgccg ccgcgcgggg
     5821 gtggagggag tcaaacggtg gcttgatttg cgtaccggtg cgcggcggcg ttccccggcc
     5881 tcgaccaggc gggtcggccg gagcccggtc gcccgttcag agaccgctcg cgtgctcctt
     5941 cagggcggtc ggatcccagc actcggaatg accgcctgga aaagctctgc acggtggtgg
     6001 attgggcgga gcgtcgaaca gcccgtggtg cgaggaaggc cctgagcaag gatcctggcg
     6061 gagtcaggca aacacacggc ggcctggcag cagaagggaa ggcaggcggc tctgcatggc
     6121 gaaaagaagg aaagacctgt ccgctggaga cgacgtttcc tggcggagcc acggacatcg
     6181 cgtcgagggc tcggtgaccc ggaaagtcga cggacggacc gaggcagccg gccgaaaggt
     6241 cgacgcgtcg aaggaagagc cgcagtacga ggtgcggagt gacaagacgg gcaaaaaggc
     6301 cgtccaccgt ccggagtcac tgaagcgaag gaaagataac ggggccggct catgagcaag
     6361 ggcagtgaac aagaacggca gaagactctt gatcacttca gcgatgccgt gaacatgact
     6421 gcgcgagagc tggaagattg gctcgcgacc gatcagtccc gcgaggtcgg tcagaaggac
     6481 ggtggagagt ccaccggcca tgcatccggc cgacacatcg tgaagctact ccgcacccgc
     6541 aagggcgagc tcaacgacga cgacctggcg cacatgcgca aggtgaccgg ctacgtgcgg
     6601 cgacacctcg cccagcgccc tggaggaaac gcgagcgata ctccatggcg ctactcgctg
     6661 atgaactggg gacacgatcc cgagaaacag cccccgcgac atcaggcgcg gccgtttccc
     6721 ccgcatcagc tcggccgcgg tcgccgggga ctgcgaatca ccgggcaggt aggcaccgct
     6781 tagaggaggg ccgccccctg atcgtctcca gcagccttcc cgttcccgca ggcagtcgcc
     6841 ttcacgctgc cctatgagcc aggataaagc catgcggaag agtgccctca tcgtggtcga
     6901 catgatcaat acgtacgatc accccgacgc ggacctgctc gttccctccg tacgcgacgc
     6961 acttccccac atctcccgac tcctcacccg cgcccgcgcc cgcgccgaag gcgtccccgt
     7021 catctacgcg aacgacaact tcggagaatg gcgatcccat cacggggaaa tcatcgagaa
     7081 gagcctcgcg ggggatcacg cggatctggt ggaagccgtt ctcccggacg ccgcatccct
     7141 cttcgtcgtc aaagcccggc actcgatctt ctacgaaaca ccgatgagct acttgctgtc
     7201 ccaactgcgt gccagtcaca tcgtgctgtc cggtcaggtc actgaacagt gcgtgctgta
     7261 ctcagcgctc gatgcccaca tccggcatct gcaggtcacc atccccgaag acgcggtagc
     7321 acacatccac cacgacctgg ccgacgctgc tctgcggatg atggaacgca acatgggagc
     7381 caccatcacc aaagcgaacg atgtcacctt ctgaaaccgg gagtgaaacc gcttcgcacc
     7441 accagaagga ggacgcagga ccgggccagc cgccttcttc catgagtgaa cacagaaatg
     7501 aagaaatggc gtgactcggt tgtcctgcgt ccagccacag aaaaccgcac ggaccacacc
     7561 ggcctcgttc agtcatccgc agatttgccg cccggtttcc ccgtcgacct tgtcgccccg
     7621 gcgcagtgcg ttgagattga ggaagatggc tgggcccgtc ctggtgtcgt ggtggcccac
     7681 cagcagggcc gttccgttct caccgagtga gggcaccaga ggcgcgtgcg agacgggcac
     7741 gtgctgatcc ggttcgtgcg acgagtccga ggacaccctg acgatgccgg ccaccagaga
     7801 gaacgtcacg ctcagcgtca tcgtgagacg gcatgcacgc gtcggccctc gtcgtctccc
     7861 tcggcagcga gagctacgcc tcaccacgag gcgacgtgcg gaccggcgca tcacgatccg
     7921 ccccgcggcg cccgccgccc cagcaaccag ccgcgcacgg tggttgtggg ctacatccgc
     7981 aagcacgtcc aacgcggagg ccggacgagg gctgatcagg ccgagcagcg agtagccccg
     8041 tctgcgcagc gtcggcgggg aagcgcccgc acggcacccc cggcctacgg gtccaagccg
     8101 ggcggggcgt cgggcgcagg acagatgcgg ctgccggcgt gatcgaagac gtacagctgc
     8161 ctcagatcga ccagaagcgg cacctgtgct ccgacctgcg cgcgttcccg cggtccgata
     8221 cggagcacga ggtcgctggc taccgtcgta cgccgctcgt gcaagatggt cgggctgccg
     8281 gaaccagccc tcgctccacg cgacaccgcc gcccctccgt ggagcagggc cgtcagccag
     8341 tcagccatcc gggtccctcc ctgtttcttg ggcctcctgg gcgatcgccc gtccgggacg
     8401 aagcgggagg cttccagctc cggcacgaac gccggacggg aaccggtgtt caggtgcacg
     8461 aacgcttcgt gaccctggta ctcgatgtgc tccacgatgc ccgtcagtgc cgcctcggac
     8521 ggccgcgcct gactgcgagg cgccatgcgg acggcctcgg agcgcagacc cacgatgacc
     8581 cgacgtcctt gctgaatgcg caggagctga tggtcgacgc tcagcggttc ggggagcacc
     8641 aagcgttgcc gtccgagttc gagcgtcatg gggccgtcca ggggtgcgag gacgacgccg
     8701 tcgagcagat tgatccgcgg ggtgccgacg aacgccgcga cgaagacgtt ggccggtctc
     8761 gcgtacaggt cgcggggcgg gctcacctgt tgtagcgctc cgtcgcgcat caccgccacg
     8821 cggtcaccca gggacatcgc ttccgcctgg tcgtgcgtta cgtagacggt ggttaccccc
     8881 agatcctgtg tgaggcgtgc gatctcggcg cgcaactggc cacgcagctt ggcatccaag
     8941 ctcgacagcg gctcgtccat gaggaagatg gaagggcggc gggaaattgc acggcccatg
     9001 gccacacgct ggcgctcccc tcccgagagc tgaccgggtc gccggtcgag caggtcctcg
     9061 atggcaagca tgcgtgcggt cgcggtcacg gccggatcgg ggtcgacctg cgagtcctgc
     9121 aagcggagag ggaagccgat attctcacgg gccgtcatgg acgggtacag cgcgaagttc
     9181 tggaagacca tggccatgtc gcgctcgctg ggcagcgtgt ggtttgcgaa gtcactcccc
     9241 aggaagagtt cgccgtcggt aatgtcctcc agcccggcga tcagccgcag cactgtggac
     9301 ttgccgcacc ccgacggtcc gagcaggaca agaaactcgc ctcgggcgac ggtgagggaa
     9361 aggtttcgga cggcgtggga gctgccgaag actttgttga ccttgcggag ctcgatggct
     9421 cgactcatgt ggaccgtccg ggcgaggaga atgacgtttg gtgacgtcgg gcaagccccg
     9481 tcgccggcct catgaacagc agaccggccg gcggttcgcc acgggtgaga cggcgggcac
     9541 gcagcggcgc ggcggtccct tctaccgagg ggcccgcccg ggcggcgggc ccctccgtgt
     9601 tcactgcgtc ccggtgggga ctactcgatg ttgatcttga atgtgctggt cttgttgcgg
     9661 acgtcctccg cgttgccgct catccgcaga tcgcggaagg tgacctcacc cacggccgga
     9721 ccctgaccgg gctcgggcat ctcgttcgcc cagataccga agccggactt ggcgtcgaac
     9781 tcgtctccgc tcttctttga gttggtgatg gagatgtcgg agaagacggt gtccttgacc
     9841 gggaactgcg gctggcctcc cacgtagttg gtctggaaca tcacgccacc gtaggtggag
     9901 tcctcgatgt cgacgtcgtt gacccggatg ccctggaaca ccttggaggc ggagaaggcc
     9961 cagatggccg ggaagacctg cccgttccag aagtggccac cggtgcgttc cagggagacg
    10021 ttctcgatgg tcgtgggttc ggtcccgaag ccgttcatcg ggtagccgaa gtccagcgag
    10081 gagatggtga tcccggagta gacgagcgtg tcggcgatac ggatgttgcg gaaggtgttg
    10141 ttgtagccgc cgtacaccgc caggcccgcg gcccgccacg tgagggtcga tgtcaggttc
    10201 tcgtagacgt tgttcttcat gtccgctccc ccggcgtcga tcgccgagaa cagcgcgaag
    10261 ctgtcgtcgc ccgtggcgcg ggcgtcgttg ttgaccacgt ggttgtccgt cgaaccgttg
    10321 gtcatgttca gaccgtcggc gaacatgttg cggatccggg agttcttgat ggtgacgttg
    10381 tcggtgttgg cgccccagta gaggcacacc atgtgctcgt tccagatgtt gtcgatggtg
    10441 atgtcggaga cgttggcgaa gtcgaagacc ttgccggggc cgtcgatcct ggagacgtag
    10501 ttgccgaagt aggcgaaccc ggagaacgag gatcccttgg cggtgttgtc ggcccggaag
    10561 ccgatgtccg tgttctcctg cgacgagggg gcgtggaacc gggtgaacca gggcccggcc
    10621 ccgaccacct gcacggcctt gccgtagacc tggaacttgc tggacgtctc gtagtcgccg
    10681 gcgggcagga acaccccgac cagcttgccg gtgctgtcca tgcgcacctt gtcgagggcg
    10741 ttctgcacgt cctggtgcga gaagccggcc gggaccgtgt acgcagccgg gtcggggttg
    10801 gccgcggcgg tggccagttc ggtgttgatg aagtcgatgg cgtagttcgc gctgttgccc
    10861 gcgtccttct ggagacggat cttggagccc gccgggaccg tcttcccgag ctgcaggttg
    10921 gcctcgtcgt agatgtggcg cggggcacct gcacccggag agttgctcgg agccgcctcg
    10981 ttgccgtaca gccaggcgta cttcggggtg aggtcgatcg tcttgaggaa ctcgccgtcc
    11041 acgtacacgt tcagcgtgga gtcggggccg tccggcatgg agaaccgggt caccagggtg
    11101 ttggtcgcgg cgcgggtggt ccactcgacg tactgaccgg tcccggtgag cgtcaccgcc
    11161 ttgcggccgc ttgcctcacc ggcgatgtca ccgatggtcc ggttcgggcc gacggtcttg
    11221 gcaccgccac cgagcacgcc gtcctccgcc tcgtacatgt cgtagggcat actcgccccc
    11281 cggccgacga aaagcgactg cgaggtggtg ttgttggccc gcttgacggg cagctcgttg
    11341 gcgtcgtcgg cgatgacggt cttgacggtg tacttgccgt tgcccgccgt ccatgccccc
    11401 agggcgaccg gggcggtcgt ccgtccggcg gtgatgacac cgttgtggga ggcgttgagg
    11461 gttttgacgg tctcgccctt gtcgtcctgg atcaccaggc tgacgtcatg gtttccggac
    11521 gccgagtcgg tcgtcccctg gttcttgatc gcgacggaga acttgacctc ttccccggca
    11581 gccgggctgg agggggccca ggagaccggt gccgcgagaa ggtcggagct gtccaccggc
    11641 ttgacgacga gggccgcggg ccgggtgaag gcgttgttcc cctcgttctg ttcgacgacc
    11701 ttgttcgcgg ggtcgacctc ggctccgacc tgataacttc cctccgcctg ggcatcgata
    11761 cgcgccgtga cgttcttgga cgcgccggcc gcgagcgcgg gcacgtccgc cgaaccgacc
    11821 ttctcaccgc ccagcgtgaa gtccagggtg gtcgccgcgg cttccttgct gccgctgttg
    11881 gcgaccgcgg ccgtgagcgt gatcgggtcg gactcgaccg gggcggcagg cgcgtgggtg
    11941 atgcccgtga cctggagatc cgggttggcg gccggtgtgc cgatcacctg gacctcggcc
    12001 acctgggccc cgggggcacc ggtgttcttg gtgaacttga gctgcaggtc ggcggcggac
    12061 ccggagacgg ggatggtcac cgtgttgccg tcggcgggcg agaacgcgta gtccttcgct
    12121 gccacgaggt tcgtgaatgc cgtcgcgccc tggccgcggc cgagcacctg gatgttctgg
    12181 gtgcgggacg accaggcggc gtcggggttg agcttgacga cgacctggct gaggtcggcc
    12241 tcggagccca gcttcgtcgt gagcgtcgtc gggtaggagc cgcccccgcc ctcccagtag
    12301 gtgctggtga gaccgtcgtt ggcgttcttc gccacatagg tgtcgtggct cgacgaggcc
    12361 tcgatgggct tgccctgggc gaggtccgcg ccgccgccgg aaccgcgtcg cgtgacgctg
    12421 ttgctcggcg cagactcgtt cccggccgcg tccttcgccc gtacgtgata agtgacggtg
    12481 gacgaggcgg tcgggcggtg ggcgaacgag gtgacgtcgc ccgcgacgga gtcgacgcgc
    12541 tcgtcgttgg cgtagatgtc gtaggcggtg acgccgacgt tgtcgtcgga ggcctgccag
    12601 gtgagctcga cctctccgcc ggactgccgg aatgagaggt tccccggggc ggtgggcgcc
    12661 tgggtgtcac cgcccgcgcc cttccgggtg acgctgttgc tgttggagga ggtgttgccc
    12721 gccgcgtcct tggcgcggac gaagtacgtc acgttcgcgt cgccgggctg ggtgtcggtg
    12781 tacgtcaggg cgctcgaggg gaggctcgcg cgcagctgac cgttggcgta gacgtcgtag
    12841 ccggtgacgc ccgtgtcgtc ggtcgccgcc ttccaggaca gtttgatctg cccgtcgccc
    12901 ggctcggtga aggccaggcc cgagggcgcg gtgggcggct cggtgtcgcc ggcggcggga
    12961 ccgtagacct ccagctcgga caactggccg gccggccagc cggtgttggc ggtgatcagc
    13021 acacgcacgt accgagtcgt ggtggcgtcc aagctgatgc tcgccgcctg gtcgttgccg
    13081 ttgttgaacg cgtacgcctt ggactgtgtg aggtcggtga agttctggtt gtcggtcgat
    13141 ccctggatct tcagggtctg gctccgctcg ggccatccgc ccggaaggcg cagcgtcacc
    13201 tggttgacct tgaccgagga gcccaggtcg acctgaaccc actggggaag ggcgttgttc
    13261 ttgctctccc aataggtgtt gcggttgccg tcaccgacgt tgccggcgcc gtacacgtcg
    13321 gcgtgtccgc tggcgctgaa ggtcttcccc tgcgcgaggt tgggggtggc ggccgtggtg
    13381 gtgagcacct gcagctcggc caactgcgcg gtacccgctg cactgttggc gctgaattcg
    13441 gcgcggacgt agcgggcgag agtcgcgggg acggcgacct tcaccgtgtt gccgttcccg
    13501 ggactgaaga cgtactgcgc ggacggcttg agcgtggcga agctcttgcc gtcggcgctg
    13561 ccctggagcg cgaacgtctg tttgcgggtc tcccagtggg cgggcagacg cagcacgact
    13621 tcccggacgc gcttggcctg tccgaggtcg gtctgtaccc actgggccga cttcttgccg
    13681 gcctgccagt aggtgtcggc gtcaccgtcg ctgatgttgg cggccacgtg gcggcccttg
    13741 acactgccgg ccttggccgg agcgtcggcg gcggcgttcg ggccgccggc tgcctgggct
    13801 ccgagcgtgg gcagccctag gaccatgacg gtggacgcga gcgctgcggc ggcggtgcgc
    13861 cacttccagc ggctcgctgg ggatgggggc atgcggggtt cctccctgcg aaggctcgcg
    13921 tgccggtgcg gcacacgaga gcggctcggt ccggggcgaa cgatggctct tcactgcggc
    13981 ggaagcagcg gctgcgtcgc gccgcgtccc tggggacgcg cacggcccgc accatcgacg
    14041 ccatgctcag cttcttgcgc tgaacgctcg taatattgca gagcgttcgc ttcccgtcca
    14101 tgggtgcgac ggcagcattt cgagaaagct cccatgcgcc gagggaccca tccaacctgg
    14161 ggagaggaag acgactctgg aagacagaga gcccttctcc tcgtcgtgca ggagaagggc
    14221 caggtagagg tatgaatttt gcaagcgtgt agctgattat tcccatgaat ggactgcacg
    14281 ttgcagatga gagtcgcttc agaaccgctc acactgcccg tactgcttcc gggatcccgg
    14341 agcggcccgt gggcctcctc agagaagtgg ggccgagcca tcaagggccg ggcggaggta
    14401 gaagacctcg gggtcacctt cgtcgagacc gtggagcaga cccaccgcat gccaaccggc
    14461 gctcaggagc agtcgctcca tcggctgatt ggaggcgttg accgaggtga aaagcttggg
    14521 agtggcgcac gagttggcca tggcgtccag cagagaccgt ccgacgcctc ggccccgtgc
    14581 ccgaggcgcc accatgagca tcgtgatgaa cccctggtcg aagaacgtgt actcccgcac
    14641 gccgtagcca aggagaccgg acgcgtcctc cgccacgagc gccaggccct cacggcacca
    14701 ccgcgcgacg gccgcccggc gcggggggct cccgtgcgca gcgatcgggt cgatcgaggc
    14761 gatcgcggcg gcctcgtggg cgcgaacagc gcgcacggtg aaggtctcgg agtccggagt
    14821 gttcatatcc cccctgtcag tacatacctg gcgtacgtct gcatggctga tcgcccccgc
    14881 ggccgttctc gatactccgg ccccgcatcc cgcagccgta gccgaaactg ctgcctcggc
    14941 tacggctgcg tcccccgttc cgccgggtcg cggggcatgg ctgtgtgcgc ccgggcgact
    15001 acgggcgttc ggtcaggcgc ggagccagac cgtcgtgtcc tgcgggagcc gaccttcccc
    15061 gtcgagcggg ccgctgctca gcagacgagc acggtgagcc ggcagttcga cggccttcgc
    15121 ggagaggttg accaggcaga tgagtccgcc ggggcgggag aagtgcagta cgccgtctgg
    15181 cccgggtttc caggtcaggg gcccgtcccc gaatccgttc tcggaacgtc tcaggctcag
    15241 ggcctcgcgg tagagcgcca gcatggagcc aggctctccg gcctgacggt cggccgcgta
    15301 gtcggaccag tcccccggtt gcggcagcca gggctccctg tccgcgccga agccgtaatg
    15361 gggctcgtcg gccgcccagg gcatcggtac ccggcatccg tcacggcccg ggtcggcgcc
    15421 gccggagcgg aagtgcatgg ggtcctggat gcggtcacgc gggatgtccg cctccggcag
    15481 ccccagttcc tcgccctggt agaggtacac cgatccgggc agcgcgaggg tgagcagggc
    15541 ggccgcgcgg gcccggcgtg tgccgaggtc gaggtcggtc ggcgtaccga atgccttggt
    15601 ggcgaagtcg aaaccggtgt cctcgcggcc gtagcgggtc acggtgcggg tgacgtcgtg
    15661 gttgcacagg acccaggtgg ccggggcgcc gaccggttcg tgttcggcca gggtgtcgtc
    15721 gatggcgcgc cggaggcagg cggcatccca ctggcaggcc aggaagttga agttgaacgc
    15781 ggtgtgcagt tcgtcggggc ggaggtagcg cgcgaagcgc tccgcgtcgg gcagccagac
    15841 ctcgccgacg aagacgccct cgtactcgtc cgcgatcttc cgccaggagc ggtagatgcc
    15901 gtgcagctcg tcctggtcga tgtacgggtg ggggtcgact cccttcacaa agtcgggcag
    15961 gtcagggtcc ttggccaaca gcgccgcgga gtcgatgcgg acgcctgcga ctccccgctg
    16021 aaaccagaag cgcaggattt cctcgtgctc acggcggact tcggggtgcg cccagttgag
    16081 gtcgggctgt tcgggggtga acaggtgcag gtaccactcg ccgtcgggaa cccgggtcca
    16141 ggtggttccc gagaactccg acggccagtc gttgggcggc agctcaccgt ccgccccgcg
    16201 gccgggccgg aagtggaaga gttctcgctc ggggcttccc gggccggccg cgagcgcggc
    16261 ccggaaccag tggtgctggt cggacacgtg gttgggcacg atgtcgacga tggtgcgcag
    16321 accgagttcc cgggcctcgg cgatgagctt ctccgcctcg cccagggtcc cgaaggcggg
    16381 gtcgatggtg cggtagtcgg cgacgtcgta gccgccgtcg accagcgggg acacgtacca
    16441 cggggtgaac cagacggcgt caacacccag ttcgacgaga tacggcagtt tcgccctgac
    16501 gcccgacaga tccccggtgc cgtcgccgtt gccgtcggcg aaactacgcg gatatatctg
    16561 gtagatgacg gcgtcgcgcc accagtcgtc ggagcggagc ggaaggggag ctgccac
//
