LOCUS       reptomyces_RBGC_435193 16964 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_435193
VERSION     Streptomyces_RBGC_435193
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001866665.1
  ORGANISM  GCF_001866665.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..1884)
                     /protein_domains="PF00664"
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217859"
                     /pseudo=False
                     /translation="MSMETTAWTQLHSVMNAQDDRRPFARATLRRIGAFARPHRAGIVR
                     FVLFGVVTALLAVATPVLAGRVVDAIVAGHDSGKVVRLSLLIALVALAEAGLGILGRRL
                     SSSLGEGLILDLRTAVFDHVQRMPVAFFTRTRTGALVSRLNNDVIGAQRAFANTLSGVV
                     SNVVTLVLTLAVMLTLSWQITLLALVLLPVFVLPARRMGSRMARMQREAAALNAAMGTR
                     MTERFSAPGATLVKLFGRPEEESAEFAARAARVRDIGVRTATAQSVFITSLTLVSALAL
                     ALVYGLGGWFALHGTLQAGAVVSLSLLLTRLYAPLTALAGARVEVMSALVSFERVFEVL
                     DLTPLIEEKPDAVEVPGGPVAVEFDDVRFSYPAADQVSLASLEEVATLDTRGGAEVLHG
                     ISFRAEPGQTVALVGSSGAGKSTIAQLLPRLYDVDAGAVRIGGTDVRDLTAASLRATLG
                     MVTQDGHLFHDTVRANLLLARPGAGDEELWDALGRARLDGVVRSLPDGLDTVVGERGYR
                     LSGGERQRMTIARLLLARQRVVILDEATAHLDNTSEAAVQEALAEALEGRTAVVIAHRL
                     STVRAADQILVVESGGIAERGTHEELLAAGGRYAELYRTQFAERGDEVAPA*"
     CDS             1955..3012
                     /protein_domains="PF03706"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217860"
                     /pseudo=False
                     /translation="MTTACKPPSPNPPPAVGTARKTSPGVTAPHFPALRTRRLPALARR
                     LPVRQILCLLPLVLVTVVAVQNRSVLVEGFGRLRTASWPWLLAAGGATCLTWVAAAFTR
                     QGAVVQPLPRWRLLATQFAAGSANHLLPTGLGAGAVNLRFMTVCGVPLARSSAALALYL
                     LAESVGRLSLLAALLFAFPDALRLGTLIPAGAVGPLLVIAGAVLVVAVAALALVRRLRT
                     AVLGFVRTALGEARSVHTRPARALALWGGSLAFPALQAAGLVAVGQALGLPVPPAHMAL
                     AYLAATVAVALVPTPGGIGSVEAALIVALVAAGGPVAVATAVVLAYRIITVWVPLVPGA
                     LTLGALVRFKVI*"
     CDS             3053..3816
                     /protein_domains="PF00378"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217861"
                     /pseudo=False
                     /translation="VPVRVEREGYVTTVVLSRPECRNAVDGPTAVELADAFREFEADER
                     ARVAVLWGEGGTFCAGADLKAIGTPRGNRVAEDGDGPMGPSRMRLSKPVIAAVAGHAVA
                     GGLELALWCDLRIAEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGASRAMDLILTGRPVP
                     AREAYEMGLANRVVPTGSARAEAEALAARIARFPQACLRSDRASVLDQQGLTEEAALRT
                     ELRHGVGVLAQSTEGAARFASGAGRHGSFGES*"
     CDS             complement(3855..4474)
                     /protein_domains="PF12840"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217862"
                     /pseudo=False
                     /translation="VRARVRDTLEQCAEAFFDAAWAEVAVQLATDLRLKNDLLGRQGVA
                     AALASVSGAVTLAADGDRIVVDEVQDKATAARAAVTFIPSVFGRPHLVAVHAPGWHPVV
                     QYPVPEPGPAEPVSLETVTLRLEALAHPVRLRLLRTLARGPHTTGELAHFWELSPPEVS
                     RHLAVLRRAGLLTARRQGRYVRHTLDLPALTALGTDLLAAVLR*"
     CDS             4822..5609
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217863"
                     /pseudo=False
                     /translation="MVPGLGQHVQHRGQFGQRGGGEAQSLGRQAADVDPQRHPSSSPTG
                     RCWWSPSRSRSPSRCPASPGGPCWRSPVWCSPCPTSASSRPPRRATAGPPRPSPRCPCS
                     APWARSSMRAAPPRSSPPSPRPTSSGARSPASSSPRGSASPSPRRSSPCSRPTARPPSG
                     ATSPPRRCSPPAPSPAARTAKTGEHGPATARPGPAADQPRLTRTSPPPGSTRSCQRAVS
                     VRGRCGNSAPGHGRSRCSRRPSWWTRNTAGRGERASSRRT*"
     CDS             complement(5421..6733)
                     /protein_domains="PF07992"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217864"
                     /pseudo=False
                     /translation="MTAERGAPGPPVRRVDVLVVGAGPAGLAAAARLAASGAGRVEVLE
                     REQEAGGVPRHCAHGGFGTRAHPLTGPAYARLLTKAAERSGAVIRTGVTVLDWGVTGVP
                     ESVAAPGAADRDVPPCPVLTAVGPGGPETVEARAVVLATGARERPRTARLVPGTRPAGV
                     YTTGELQQSVHLFGQRVGTRAVVVGAEGVSYAAADTVRAAGAEVVALVTEQPRAHVPAF
                     RAQSVRLRRRVPLLTDTTVTELLGHGRLSGVRVRHRDGRTTVLACDTVVFTGDFVPEHE
                     LARRGALVPDPGTRGPAVDGALHTSRPGVFAAGNVLHAVEPAGTAAREGARAARAVLDL
                     LAGGAWPGPGVPLTVEAPLRWIAPNRVTPAARPERYVLRDDALSPRPAVLRVHQDGRLL
                     HRERPWPGALLPHRPLTLTARWHDRVDPGGGEVRVSRG*"
     CDS             complement(6731..8187)
                     /protein_domains="PF01266"
                     /protein_domains="PF04324"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217865"
                     /pseudo=False
                     /translation="MTGTVTVTAHGPLPAEPYDVAIVGAGVVGCAIARELARHPDLRIA
                     LLEAQDDVGQGTSKANTAILHTGFDAVPGTLEARLVREGYERLGAYAAETGIPVERVGA
                     LLVAWDEEQRAALPRLADKARRGGYDATRLLPADEVYAREPHLGPGALGALHVPGESII
                     CPWTTTLAYATQAVRAGVDLHLNTTVEEVGRGEVHQLRTSRGPLRARRLVNAAGLHADT
                     LDRLLGHEEFTVTPRRGQLLVHDKLARPLVRHILLPVPTALGKGVLVAPTVHGNVLLGP
                     TAEDLDDKRATGSTAAGLAALREQGRRILPALLDEEVTAVYAGLRAATGREDYRIAAHP
                     EQGYVTVGGIRSTGLTASLAIAAHVTGLLADTGLDLGPVRDLAPLTMPNLGEAFPRPYQ
                     RPELIAADPEYGTLVCHCERVSRGEIRDALASPIPPRSLDGLRRRTRARAGRCQGFYCG
                     AAVRELFERAQGEAAQGEATRSEEARS*"
     CDS             complement(8185..9614)
                     /protein_domains="PF00370"
                     /protein_domains="PF02782"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217866"
                     /pseudo=False
                     /translation="MTGPVLAVDQGTSGTKALVVCPERGVLGTGFAEVRPRYLPGGLVE
                     ADPTELYDSVLAAGRQALAEASEPVVALGLANQGETVLAWDPASGRPLTDALVWQDRRA
                     DSVCTELAAHADELRHLTGLPLDPYFAAPKMAWIRRRLTREGVVTTSDAWLVHRLTGTC
                     ATDAATAGRTQLLDLDSAQWSPRALEIYGLADERLPQVTDNAQHIGTTTAFGPEIPLTG
                     LAVDQQAALLAQRVTRPGAAKCTYGTGAFLLAHTGERARRGGSGLVSCVAWRIAGTTSY
                     CLDGQVFAAASAVRWLTELGVLSGAADLDAVGGAVPDSGGVTFVPALAGLAAPWWRGDL
                     RGSLTGLGLDTTAGHVARALCEGIAAQVAQLADAAAEDLGTGLDLLRVDGGLTRSALLM
                     QTQADLLQRPVEVSALPDATALGAATLARLGADPALGVDHVLPGPEPAAVYEPRIGADQ
                     AAERRARFRTAVQALLDA*"
     CDS             complement(9654..9886)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MLRLWPSAVGPGPPEHGRGGGVAWQQPSCGRGLGVVRWSAVTIEG
                     EVPAHHCCQLNYQSGPVDGPSVLDSGHGATAG"
     CDS             9869..10842
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217867"
                     /pseudo=False
                     /translation="MARDGARPSYDPAGPDRALRAALQDLRTGRWMAMRTLLADTADRW
                     QWTQRTQVLAAAAAGSDVVRAWLAEEPDSAHALVMHARVAVERALRAQRERHLRTHELW
                     IEAWDAAQAATRAAPHDAVPWVCLVALAQLDPEQRWEEHRAVAPEPLLPPGPWGLLAEA
                     HKRDPFNREAHHRMLQFLYARRGTGRLAEAAGYAQWAAGQAPAGSALHVLPLYVRVERY
                     RRESGHDAALDLHWVAEEAAREARRALHSWFEHTHRGERSLLDLNHVAHALWGSLQFPD
                     AARVFDAIGPYVTPTPWMYRAPGRDRAVEVFLQARDRCRAARS*"
     CDS             10892..12441
                     /protein_domains="PF13520"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217868"
                     /pseudo=False
                     /translation="MSATPDPTPAPLSSPSPGLPQQDEEQRLRELGYRPVLARRMGGFG
                     NFAISFSVISILSGCMTLYGFGLNTGGPAVMLWGWAGVGLFVLCVGLALAEVTSAYPTS
                     GALYYMADRLGGRRWGWYTGWLNLLGLLGAIAGIDYGAALFTGAFANLQWGFTPTPGRT
                     MLVFCAILLLHAVLNLFGVRLVSVLNSVSVWWHLAGVAVIVGALAIVPDHHRSASFVFT
                     KFVNETGWHNPLYVAAIGLLLAQYTFSGYDASAHLSEETSQASVSAAKGIVRSIWASWL
                     AGFVLLAGLTFAIQDYDATRTTATGVPPAQILLDGLGTDGASALLLVVITAQLFCGNAE
                     VAAASRMVFAFSRDGALPGSRLWRTVSGRTQTPVAAVWLAVIVACVLALPSLYSATAYN
                     AVTAINVIGITPAYAIPVLLRLRAGDRFRPGPWQLGRWSRPIGWIAVVWVACVTVLFCL
                     PQASPVTVDTMNYASVALVAVLVLASVWWYVARRSYGTPTTAAYGDDREQAELAEGII*
                     "
     CDS             12624..13720
                     /protein_domains="PF00924"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217869"
                     /pseudo=False
                     /translation="VNRAPTLDDLVLAGIALAAGLLLAFLSRAVLRWLAGHAKRTKWSG
                     DDVIVDALRSVVPWAAIAGGAAVAAAALPLTRTVQHHTDQILEVWLIFVATLSAARVIA
                     GLVHTVTQSRSGVAGSATIFVNITRVLVLAIGFLIVLQTLGISIAPLLTALGVGGLAVA
                     LALQDTLANLFAGIHILAAKTVQPGDYIRLGSGEEGYVVDINWRQTTVRQLSNNLVVIP
                     NGQLAKANMTNFTRPEQRLTVLVQVGVAYDADLEHVERVTKEVVAATMREVPGAVPEHE
                     PAVRFHTFGDSRIGFTVILGVGEFSDQYRIKHEFIKRLHRRYHEEGIRIPAPARTVALQ
                     QAAVVIPQQRSGEDVLPGVIPGTTE*"
     CDS             13871..16089
                     /protein_domains="PF03971"
                     /protein_domains="TIGR00178"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217870"
                     /pseudo=False
                     /translation="VTDSTIIYTYTDEAPALATHSFLPVIQAYASQAGVPVTTRDISLA
                     GRIIAHFPEYLNEDQRIPDALAELGELAKTPAANIVKLPNISASIPQLKAAVAELQGKG
                     YALPDYPDDPKTDEEREIRARYDKVKGSAVNPVLREGNSDRRAPASVKNYAKTHPHRMG
                     AWTAESRTNVATMSENDFAATEKSTVVAEDGTLRFELVGADGTATELREPLKVVAGEVV
                     DAAVLRVAALKEFLAAQVARAKAEGVLFSVHLKATMMKVSDPIIFGHVVRAFFPKTFAQ
                     YGETLAAAGLSPNDGLGTILAGLANLPEGDAIKASFDAELADGPALAMVDSDKGITNLH
                     VPSDVIVDASMPAMIRTSGHMWGPDGQEADTLAVLPDHSYSGVYQAVIEDCRAHGAFDP
                     ATMGTVPNVGLMAQKAEEYGSHDKTFEIPADGTVRLVDAAGDVVLEQAVAKGDIFRACQ
                     TKDAPIRDWVKLAVTRARATGDPAVFWLDENRGHDAVLIEKVKAYLPEHDTEGLDIKIL
                     SPVEATKLSVERIRRGENTISVTGNVLRDYLTDLFPILELGTSAKMLSVVPLMAGGGLF
                     ETGAGGSAPKHVQQLVKENYLRWDSLGEFFALVPSFEQYAEATGNARAKVLADTLDRAT
                     ATFLNEDKSPTRRVGGIDNRGSHFYLSLYWAQELARQTDDADLAKVFAPFAESLAADEQ
                     KIVGELLAVQGEPADIGGYYQVDQAKADAVMRPSATWNATLASLS*"
     CDS             16186..16964
                     /protein_domains="PF05013"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7217871"
                     /pseudo=False
                     /translation="VPSFELLPGDPGSPVLLHVPHSARAIPADVRRGIVLDDAALEREL
                     DHITDAHTAELAERAAESAGVTPWRFVNRLSRLVVDPERFPDEREEMAAVGMGAVYTRT
                     THQGELRRPDTDPEPLLERWFRPYARAMTEAVADRLAATGRAVIIDVHSYPTAPLPYEL
                     HAAGPRPAVCLGTDAFHTPPRLAEAAREAFAACGETGLDSPFAGTYVPLEFHGGDSRVG
                     ALMVEIRRDTYMAEPGGAAGPGLERLAGALAALVDSV*"
ORIGIN
        1 tcaggccggt gccacctcgt cgccccgctc ggcgaactgc gtccggtaca gctcggcgta
       61 ccggccgccg gccgccagca gctcctcgtg cgtgccgcgc tccgcgatcc cgccggactc
      121 cacgaccagg atctggtcgg cggcccggac cgtggacagc cggtgggcga tgaccacggc
      181 ggtccgcccc tccagggcct cggcgagcgc ctcctggacg gccgcctcgg aggtgttgtc
      241 caggtgggcg gtggcctcgt ccaggatcac cacgcgctgg cgggccagca gcagccgggc
      301 gatcgtcatg cgctggcgct ccccgccgga cagccggtag ccgcgctcgc cgacgaccgt
      361 gtccaggccg tccggcaggg accgtacgac accgtccagc cgggcccggc cgagggcgtc
      421 ccacaactcc tcgtccccgg cgccggggcg ggccagcagc aggttggcgc ggacggtgtc
      481 gtggaagagg tggccgtcct gggtgaccat gccgagcgtg gcccgcagcg aggcggcggt
      541 caggtcacgg acgtcggtcc cgccgatgcg caccgcgccc gcgtcgacgt cgtacaggcg
      601 cggcagcagc tgggcgatgg tggacttccc ggcgccggag gagccgacga gggcgacggt
      661 ctgcccgggt tcggcgcgga aggagatgcc gtgcaggacc tcggcgccgc cgcgcgtgtc
      721 gagggtggcc acctcctcca gcgaggcgag ggagacctgg tcggcggccg ggtaggagaa
      781 gcggacgtcg tcgaactcga ccgcgaccgg ccccccgggg acctcgacgg cgtccggctt
      841 ctcctcgatg agcggcgtga ggtccagcac ctcgaagacc cgctcgaagc tgacgagcgc
      901 gctcatcacc tccacccggg cgccggcgag cgcggtgagc ggggcgtaga gccgggtcag
      961 cagcagggag agcgagacga ccgcgcccgc ctgcagggtg ccgtgcagcg cgaaccagcc
     1021 gccgaggccg tagacgaggg ccagcgcgag ggcggagacc agggtgaggg aggtgatgaa
     1081 cacggactgg gcggtggccg tgcgcacgcc gatgtcccgg acccgggcgg cgcgcgccgc
     1141 gaactccgcg gactcctcct cgggccggcc gaacagcttg accagggtgg cgccgggcgc
     1201 ggagaaccgc tcggtcatcc gggtgcccat ggccgcgttc agcgccgccg cctcccgctg
     1261 catccgggcc atccggctgc ccatgcggcg ggcggggagc acgaacaccg gcagcagcac
     1321 cagcgcgagc agggtgatct gccaggacag ggtcagcatc accgcgagcg tgagcaccag
     1381 ggtgacgacg ttgctcacca caccggacag ggtgttggcg aacgcccgct gggcgccgat
     1441 cacgtcgttg ttgagtcggc tgaccagcgc gcccgtacga gtccgtgtga agaacgcgac
     1501 cggcatgcgc tgcacatgat cgaacacagc cgttctgagg tcgaggatga gtccctcccc
     1561 gagcgacgac gacagccgtc gcccgaggat gccgagcccc gcctccgcga gcgccacgag
     1621 cgcgatcagc agggacagcc gtacgacctt cccggagtcg tgccccgcca cgatcgcgtc
     1681 gacgacgcgg ccggcgagca cgggggtcgc gacggcgagc agggcggtca ccaccccgaa
     1741 caggacgaag cggacgatgc ccgcgcggtg cggccgggcg aaggcgccga tacggcgcag
     1801 cgtggcgcgg gcgaagggac ggcggtcgtc ctgggcgttc atgacgctgt gcagctgcgt
     1861 ccatgcggtg gtctccatgc tcatgggcaa gaacgtagaa cctcaagctt cgttgaggtc
     1921 aatgtccgcc gcatttcact cccgaaggcc ccgatgacca cagcctgtaa accgccgtcc
     1981 cctaatccgc cacccgccgt tgggacggca cggaaaacct ctccgggtgt gaccgcgcca
     2041 cacttccccg ccctgcgcac gcgccgcctg ccggcgctcg cccggcgcct gcccgtgcgg
     2101 cagatcctgt gtctgctgcc gctcgtgctc gtgaccgtcg tcgccgtgca gaaccgctcg
     2161 gtgctcgtcg agggcttcgg ccggctgcgc acggcctcgt ggccctggct gctggcggcg
     2221 ggcggcgcca cgtgtctgac ctgggtggcc gccgccttca cccggcaggg cgccgtcgtc
     2281 cagccgctgc cgaggtggcg gctgctggcc acccagttcg cggccggctc ggcgaaccac
     2341 ctgctgccga cggggctcgg cgccggcgcg gtcaacctgc ggttcatgac cgtgtgcggg
     2401 gtgccgctcg cccgctcctc cgccgcgctc gcgctgtatc tgctcgccga gtcggtcggc
     2461 cggctgagcc tgctggccgc gctgctgttc gccttccccg acgcgctgcg gctcggcacc
     2521 ctgatcccgg ccggggccgt cggcccgctg ctggtgatcg ccggagcggt gctggtggtg
     2581 gcggtcgccg cgctggcgct cgtacgacgg ctgcgcacgg ccgtgctcgg cttcgtccgc
     2641 accgccctgg gcgaggcccg ctccgtgcac acgcggccgg cccgggcgct cgccctgtgg
     2701 ggcggctcgc tcgcgttccc ggcgctgcag gccgccggtc tggtggcggt cggacaggcg
     2761 ctggggctgc cggtgccgcc cgcgcacatg gcgctggcgt acctggccgc gacggtggcg
     2821 gtggcgctgg tgcccacgcc gggcggcatc ggctccgtcg aggccgcgct gatcgtggcg
     2881 ctggtcgcgg cgggcggccc ggttgcggtg gccacggcgg tggtgctcgc ctaccggatc
     2941 atcacggtgt gggtgccgct ggtgcccggg gcgctgacgc tgggggcgct ggtgcggttc
     3001 aaggtcatct gaggcagagt ggcgctccca gccgagacga gggagttcac cgtgccggtc
     3061 cgtgtggagc gcgaggggta cgtcacgacg gtcgtcctgt cccggccgga gtgccgcaac
     3121 gcggtggacg gccccacagc cgtcgaactc gccgacgcct tccgggagtt cgaggccgac
     3181 gaacgggccc gggtggcggt gctgtggggc gagggcggca cgttctgcgc gggcgcggac
     3241 ctgaaggcga tcggtacgcc gcgcggcaac cgcgtggccg aggacggcga cggcccgatg
     3301 gggccatccc ggatgcggct gtccaagccg gtgatcgcgg ccgtggccgg gcacgcggtc
     3361 gcgggcggcc tcgaactcgc cctgtggtgc gatctgcgga tcgccgagga ggacgccgtc
     3421 ttcggcgtgt tctgccgccg ctggggcgtg cccctgatcg acggcggcac ggtgcggctg
     3481 ccccggctga tcggcgcgag ccgggccatg gacctgatcc tgaccggccg tccggtgccg
     3541 gcccgggagg cgtacgagat gggcctggcc aaccgcgtcg tgccgaccgg gtccgcccgc
     3601 gccgaggcag aagcgctcgc ggcccggatc gcccgcttcc cgcaggcgtg tctgcgcagc
     3661 gaccgcgcgt cggtcctcga ccagcagggg ctgaccgagg aggcggcact gcgcaccgaa
     3721 ctccgccacg gcgtgggcgt gctggcgcag agcacggagg gcgccgcccg cttcgcctcc
     3781 ggcgccgggc ggcacggctc gttcggcgag agctgagcgc gcggcgccgg tccgggcctg
     3841 ccggtgtgcc ggctcagcgc agtacggccg ccagcaggtc ggtgccgagg gccgtcaggg
     3901 cgggcagatc gagggtgtgc cggacgtagc ggccctgccg cctggctgtc agcaggcccg
     3961 cgcggcggag cacggcgagg tggcgggaga cctccggagg cgagagttcc cagaagtggg
     4021 ccagctcacc ggtggtgtgc gggccacggg ccagggtgcg cagcagccgc agccgtaccg
     4081 gatgcgcgag tgcctccagc cgcagggtga ccgtctccag cgacaccggc tccgccgggc
     4141 cgggctcggg gacggggtac tgcaccaccg ggtgccagcc gggcgcgtgg accgccacca
     4201 ggtgcgggcg gccgaagacg ctggggatga aggtgaccgc ggcgcgggcg gcggtcgcct
     4261 tgtcctgcac ctcgtccacg acgatgcggt cgccgtccgc tgccagggtg accgcaccgg
     4321 acaccgaggc gagggccgcc gcgacgccct ggcgtccgag caggtcgttc ttcaggcgca
     4381 gatcggtggc gagctgcacg gcgacctccg cccacgcggc gtcgaagaac gcctcggcac
     4441 actgttcgag ggtgtcgcgc acccgcgccc gcaccgtggc cgggtccgcg agcagccgtt
     4501 ccgaaggcct cctgcagcgc gccgcgggcc tgggccacgt ccagggcccg ctcgcgcgcc
     4561 gtcgcgtcgg tgagcggcga cgccccggcg aagccgatcc ggttgctgcc gcacgtggtg
     4621 acgagcgcgg cggtcacgta cgtctcgtcg tcgatccggt ccacgtcgtc cagttcctcg
     4681 gcgagggtgg gccgcggccg ggcggggacc aggaagtcgg cctgtgagga acgccagagg
     4741 aactccgcct cccgcagccg ctcgtccagt tcgggccgca gcccggcccg gacgtccgcg
     4801 gcccagccgg cgagccgcgg atggtgcccg ggctcggcca gcacgtgcag catcgcggtc
     4861 agttcggcca gcggggaggc ggcgaagcgc agtcgctcgg acggcaggcc gctgatgtcg
     4921 atcctcaacg tcacccctca tcatcaccga ccggacggtg ctggtggtca ccctccaggt
     4981 cccggtcacc gtcgcgctgt cccgcttctc ccggcgggcc gtgctggcgc tcgccggtgt
     5041 ggtgctcgcc gtgtcctacc tcggcttcct cgcggccgcc tcgccgggcc acggctgggc
     5101 cgccccggcc gtcgccgcgg tgtccgtgct ctgcaccatg ggcgagatcg tctatgcggg
     5161 cagcgccacc gcgctcgtca ccgccctcgc cccggcccac gtcctcgggc gcacgctcgc
     5221 ccgcttccag ctctccacgg ggttcggcct cgccgtctcc ccggcggtca tcaccatgct
     5281 cgcgacccac ggcccgaccg ccctctgggg cgacctcgcc gccgcgacgc tgctctcctc
     5341 cggcgccgtc gcccgcggca aggaccgcga agaccgggga gcacggcccg gcgacggccc
     5401 gacccggccc ggccgcggat cagccgcggc tcacccgcac ctcgccgcct ccgggatcga
     5461 cccggtcgtg ccagcgggcg gtgagcgtca ggggacggtg cggcaacagc gccccgggcc
     5521 acggccgttc gcggtgcagc aggcggccgt cctggtggac gcgcaacact gcgggccggg
     5581 gcgagagggc gtcgtcgcgc aggacgtagc gctcgggccg ggccgcgggc gtgacgcggt
     5641 tcggggcgat ccagcgcagc ggggcctcga cggtgagcgg gacgccgggg ccgggccagg
     5701 cgccgcccgc gaggaggtcc aggacggcgc gggccgcccg ggcgccctcg cgggcggcgg
     5761 tgccggcggg ttcgacggcg tgcaggacgt tcccggcggc gaacaccccg ggccgtgagg
     5821 tgtgcagggc gccgtcgacg gcggggccgc gggtgccggg gtccggcacg agggcgccgc
     5881 ggcgggcgag ttcgtgctcc gggacgaagt cgccggtgaa cacgacggtg tcgcaggcca
     5941 gtacggtcgt acggccgtca cggtggcgga cgcggacccc cgacaggcgt ccgtggccga
     6001 ggagttcagt gacggtggtg tccgtcagca gcgggacgcg gcggcgcagc cggaccgact
     6061 gcgcccggaa ggcggggacg tgggcgcggg gctgttcggt gaccagggcg acgacctcgg
     6121 caccggccgc gcgcacggtg tcggcggccg cgtaggagac gccctcggca ccgacgacga
     6181 ccgcgcgggt gccgacgcgc tgcccgaaca ggtggacgga ctgctggagt tcaccggtgg
     6241 tgtagacacc ggcgggccgg gtgccgggca caagccgggc cgtgcgcggc cgttcccggg
     6301 cgccggtggc gaggacgacg gcccgcgcct cgacggtctc gggtccgccg ggaccgacgg
     6361 cggtgagcac cgggcacggc ggcacgtccc ggtccgcggc gcccggggcg gccacggact
     6421 ccggtacccc cgtcacgccc cagtccagga cggtcacccc ggtccggatc acggcgcccg
     6481 accgctcggc ggccttcgtc agcagccggg cgtacgcggg gccggtcagc gggtgcgcgc
     6541 gggtaccgaa gccgccgtgg gcgcagtgcc ggggcactcc cccggcctcc tgctcacgct
     6601 ccagcacctc gacccggccg gcaccggacg cggccaggcg ggcggcggcg gccagccccg
     6661 cggggcccgc accgacgacg aggacgtcga cccggcggac cggcggcccc ggcgcgcctc
     6721 gctcagcggt catgaccgcg cctcctcgct ccgcgtcgcc tcgccctgtg ccgcctcgcc
     6781 ctgtgcccgc tcgaacaact cccgtaccgc cgcgccgcag tagaacccct ggcagcggcc
     6841 cgcccgggcc cgggtgcggc ggcgcaggcc gtccaggctg cgcggtggga tcgggctcgc
     6901 cagcgcgtcg cggatctcgc cgcgggagac gcgctcgcag tggcagacga gggtgccgta
     6961 ctcggggtcg gcggcgatga gttcgggccg ctggtacggg cgcgggaagg cctcgccgag
     7021 gttgggcatg gtcagcggcg ccaggtcgcg gaccgggccc aggtcgagcc cggtgtccgc
     7081 cagcaggccg gtgacgtgcg cggcgatcgc cagggacgcg gtcaggccgg tggagcggat
     7141 gccgccgacg gtgacgtacc cctgctcggg gtgggcggcg atgcggtagt cctcccggcc
     7201 ggtcgccgca cgcagcccgg cgtagacggc ggtgacctcc tcgtccagca gggcgggcag
     7261 gatgcggcgg ccctgttccc tgagggcggc gagcccggcg gcggtggagc cggtggcccg
     7321 tttgtcgtcc aggtcctcgg cggtggggcc gagcaggacg ttgccgtgga cggtgggcgc
     7381 gaccaggacg cccttgccga gcgcggtcgg gacgggcagc aggatgtgcc gcacgagggg
     7441 ccgggcgagc ttgtcgtgga cgaggagctg gccgcggcgc ggggtgacgg tgaattcctc
     7501 gtggccgagc agccggtcga gggtgtcggc gtgcagtccg gccgcgttga cgaggcggcg
     7561 ggcgcgcagg gggccccggg aggtgcggag ctggtggact tcgccccgac cgacctcctc
     7621 caccgtggtg ttgaggtgga ggtcgactcc ggcgcggacc gcctgggtgg cgtacgccag
     7681 ggtcgtcgtc caggggcaga tgatgctctc gccggggacg tgcagggcgc cgagcgcgcc
     7741 ggggccgagg tggggttcgc gggcgtacac ctcgtcggcg ggcagcaggc gcgtcgcgtc
     7801 gtagccgccc cgccgcgcct tgtcggccag ccggggcagc gcggcccgtt gttcctcgtc
     7861 ccaggcgacg agcagggcgc cgacgcgttc gacggggata ccggtctcgg cggcgtaggc
     7921 gcccagccgc tcgtacccct cgcggaccag gcgggcctcc agggtgccgg ggaccgcgtc
     7981 gaaaccggtg tgcaggatcg cggtgttggc cttggaggtg ccctggccga cgtcgtcctg
     8041 ggcctccagc agggcgatgc ggagatccgg gtggcgggcg agttcccggg cgatcgcgca
     8101 gccgacgacg ccggccccga cgatcgccac gtcgtacggc tcggcgggca gcgggccgtg
     8161 tgcggtgacg gtcacggtgc cggtcatgcg tcgagcaggg cctggacggc ggtgcggaag
     8221 cgggcgcggc gttcggcggc ctggtcggcg ccgatgcggg gttcgtacac ggcggcgggc
     8281 tctgggccgg gcagcacgtg gtcgacgccc agcgcggggt ccgcgccgag gcgggcgagc
     8341 gtggcggcgc cgagggcggt ggcgtcgggc agcgcggaca cctcgacggg gcgctgcagc
     8401 aggtcggcct gggtctgcat gaggagcgcg gagcgggtca ggccgccgtc gacgcgcagc
     8461 aggtccaggc cggtgccgag gtcctcggcg gcggcgtcgg cgagttgggc gacctgggcg
     8521 gcgatgccct cgcacagggc gcgcgcgacg tggccggccg tggtgtcgag gccgagtccg
     8581 gtgagcgagc cgcgcaggtc gccgcgccac cagggggcgg cgagtccggc gagggcgggg
     8641 acgaaggtga cgccgccgct gtcggggacg gcgccgccga cggcgtccag atcggcggcg
     8701 ccggagagga caccgagctc ggtgagccag cggacggcgg aggcggccgc gaagacctgg
     8761 ccgtcgaggc agtagctggt cgtgccggcg atccgccagg cgacgcagct gaccaggccg
     8821 gagccgccgc gccgggcccg ctcgccggtg tgcgcgagca ggaacgcgcc ggtgccgtag
     8881 gtgcacttgg cggcgccggg gcgggtgacg cgctgggcga gcagggcggc ctgctggtcg
     8941 acggccaggc cggtgagcgg gatctcgggg ccgaaggccg tggtcgtgcc gatgtgctgg
     9001 gcgttgtcgg tcacctgcgg gagccgctcg tccgccaggc cgtagatctc cagcgcccgc
     9061 ggcgaccact gtgcgctgtc gaggtcgagg agctgggtgc ggccggcggt ggcggcgtcg
     9121 gtggcacagg tgccggtgag gcggtggacg agccaggcgt cggaggtggt gacgacgccc
     9181 tcgcgggtga gccggcgccg gatccaggcc atcttggggg ccgcgaagta cgggtcgagg
     9241 ggcaggccgg tcaggtgcct caactcatct gcgtgcgcgg cgagttcggt gcagaccgag
     9301 tccgcgcggc ggtcctgcca gaccagggcg tcggtgagcg ggcggccgga ggccgggtcc
     9361 caggcgagga cggtctcgcc ctggttggcg aggccgagcg ccacgaccgg ctcggaggcc
     9421 tcggcgagcg cctggcgccc ggcggcgagc accgagtcgt acagctcggt cgggtcggcc
     9481 tcgaccaggc cgccgggcag gtaccggggg cggacctcgg cgaacccggt gccgaggacg
     9541 ccgcgctccg ggcagaccac gagggccttg gtgccggacg tgccctggtc gacggcgagc
     9601 accggcccgg tcatcgcacc gtctcccgtc gcacctcgaa gatcacaccg cgtcagcctg
     9661 ccgtcgcgcc gtgtccggag tcaagcaccg acggaccgtc aactggaccg gattggtagt
     9721 tgagttgaca acaatggtgg gccggtacct ccccctctat agtgaccgcc gaccaccgca
     9781 ccacgcccaa tccccgccca caggagggct gttgccacgc caccccgcca cctcgcccgt
     9841 gctccggtgg ccccggaccg acggctgatg gccagagacg gagcacgtcc ctcctacgac
     9901 ccggccggtc ccgaccgtgc gctgcgcgcc gccctccagg atctgcgcac cggccgctgg
     9961 atggccatgc gcaccctgct cgccgacacc gcggaccggt ggcagtggac ccagcgcacc
    10021 caggtcctcg cggcggccgc cgccggctcc gacgtggtgc gcgcgtggct cgccgaggag
    10081 ccggacagcg cccacgcgct ggtgatgcac gcccgggtcg cggtggagcg ggccctgcgc
    10141 gcccagcggg agcggcacct gcggacccac gaactgtgga tcgaggcctg ggacgccgcc
    10201 caggcggcca cccgggccgc cccgcacgac gcggtgccct gggtgtgtct ggtggccctc
    10261 gcccagctgg acccggagca gcgctgggag gagcaccggg cggtggcgcc cgagccgttg
    10321 ctgccgccgg ggccctgggg cctgctggcc gaggcccaca agcgcgaccc gttcaaccgc
    10381 gaggcccacc accggatgct ccagttcctc tacgcgcgcc gcggcacggg ccggctcgcg
    10441 gaggccgccg gctacgcgca gtgggccgcc gggcaggccc cggccggctc cgcactgcac
    10501 gtgctgccgc tgtacgtccg ggtcgagcgc taccggcgcg agagcgggca cgacgcggcg
    10561 ctcgacctgc actgggtcgc ggaggaggcg gcccgcgagg cacgccgcgc cctgcactcc
    10621 tggttcgagc acacgcaccg cggcgaacgc tcgctgctgg acctcaacca cgtggcccac
    10681 gcgctgtggg gctcgctcca gttcccggac gcggcccggg tgttcgacgc gatcggcccg
    10741 tacgtcacgc ccacgccctg gatgtaccgc gctcccggcc gcgaccgcgc cgtggaggtc
    10801 ttcctccagg cccgggaccg ctgccgggcg gcccgctcct gaccgcaccg cccccgtccg
    10861 caacgccgtc gacccggagg tctcccccgt atgtccgcca cccccgatcc cacgccggcg
    10921 cccctgtcct cgccctcgcc cggcctgccc cagcaggacg aggagcagcg gctgcgcgaa
    10981 ctcggctacc ggccggtgct ggcccgccgc atgggcggct tcggcaactt cgcgatcagc
    11041 ttctcggtga tctcgatcct gtcgggctgc atgacgctgt acggcttcgg cctgaacacc
    11101 ggcggccccg ccgtgatgct gtggggctgg gcgggcgtcg gcctgttcgt gctctgcgtc
    11161 ggtctcgcgc tcgccgaggt caccagtgcc tatccgacct cgggcgcgct gtactacatg
    11221 gccgaccggc tcggcggccg gcgctggggc tggtacaccg gctggctgaa tctgctcggt
    11281 ctgctcggcg cgatcgccgg tatcgactac ggcgccgccc tgttcacggg ggcgttcgcg
    11341 aacctccagt ggggcttcac gccgaccccc ggcaggacca tgctggtctt ctgcgccatc
    11401 ctgctgctgc acgcggtgct gaacctgttc ggcgtccgcc tggtcagcgt gctcaactcg
    11461 gtcagcgtgt ggtggcacct ggcgggcgtc gcggtcatcg tcggcgcgct cgcgatcgtc
    11521 cccgaccacc accggtcggc ctccttcgtg ttcacgaagt tcgtcaacga gaccggctgg
    11581 cacaacccgc tctacgtggc ggcgatcggc ctgctgctcg cgcagtacac cttctccggc
    11641 tacgacgcct ccgcgcacct gtccgaggag acctcgcagg cctcggtgtc cgcggccaag
    11701 ggcatcgtgc gctccatctg ggcgtcctgg ctcgccggct tcgtcctgct cgccgggctg
    11761 accttcgcca tccaggacta cgacgccacg cgcaccaccg ccaccggtgt accgcccgcg
    11821 cagatcctgc tcgacggcct cggcaccgac ggcgcgagcg cgctgctgct ggtcgtgatc
    11881 accgcccagc tgttctgcgg caacgccgag gtcgcggcgg ccagccggat ggtgttcgcg
    11941 ttcagccggg acggcgcgct gcccggctcg cgcctgtggc gcacggtgag cggccgcacc
    12001 cagacgccgg tcgccgccgt gtggctcgcg gtgatcgtcg cctgcgtcct cgccctgccc
    12061 tcgctgtact cggcgaccgc ctacaacgcg gtgaccgcca tcaacgtcat cggcatcacg
    12121 cccgcctacg ccatcccggt gctgctgcgg ctgcgcgcgg gcgaccggtt ccggccgggg
    12181 ccgtggcaac tgggccgctg gagcaggccg atcggctgga tcgcggtggt ctgggtggcc
    12241 tgtgtgaccg tgctgttctg cctgccgcag gcctcgccgg tcaccgtcga cacgatgaac
    12301 tacgcctcgg tggcgctcgt cgccgtgctg gtgctggcga gcgtgtggtg gtacgtcgcc
    12361 cgccgctcgt acggcacacc caccaccgcg gcgtacggcg acgaccgcga gcaggccgaa
    12421 ctcgcggagg gcatcatctg atccgccgct gcgcggagcg ccggtccggg tgcgaactgg
    12481 tgttccggat acggcaggat gaacgatcgc gccggtcacc gcggttcggg gccggcgcgc
    12541 tcgcacatcc cgcacatcga gcaggtgacc acgtgacgcg tcctccccac tccgcagccg
    12601 ccgcgagacc cggaggtgac cggtgaaccg cgcgccgacc ctggacgatc tcgtcctcgc
    12661 cggcatcgcg ctcgccgcgg gcctgctgct ggccttcctg tcgcgcgcgg tgctgcgctg
    12721 gctggcgggg cacgccaagc ggaccaagtg gagcggtgac gacgtcatcg tggacgcgct
    12781 gcgctcggtc gtaccgtggg ccgcgatcgc gggcggcgcg gcggtcgcgg cggccgcgct
    12841 gcccctgacc cgcacggtcc agcaccacac cgatcagatc ctcgaggtgt ggctgatctt
    12901 cgtggcgacc ctgtcggcgg cccgggtgat cgccggtctg gtccacacgg tcacccagtc
    12961 ccgctcgggc gtggcgggct cggcgaccat cttcgtcaac atcacccgcg tgctggtcct
    13021 cgcgatcggc ttcctgatcg tcctgcagac gctcggcatc tccatcgcac ccctgctcac
    13081 cgccctgggc gtgggcggtc tggcggtggc cctcgccctc caggacacgc tcgccaacct
    13141 cttcgcgggc atccacatcc tggccgccaa gaccgtccag ccgggcgact acatccggct
    13201 cggcagcggc gaggagggct atgtggtgga catcaactgg cgccagacca ccgtccgcca
    13261 gctctccaac aacctggtgg tcatccccaa cggccagctc gccaaggcca acatgaccaa
    13321 cttcacgcgc cccgagcagc ggctgacggt gctggtgcag gtcggggtgg cgtacgacgc
    13381 ggacctggag cacgtggagc gggtgaccaa ggaggtcgtc gcggcgacca tgcgcgaggt
    13441 ccccggagcg gtcccggagc acgagcccgc cgtccgcttc cacaccttcg gcgactcccg
    13501 catcggcttc acggtgatcc tcggcgtcgg cgagttcagc gaccagtacc gcatcaagca
    13561 cgagttcatc aagcgcctgc accgccgcta ccacgaggag ggcatccgca tcccggcccc
    13621 ggcccgcacg gtggcgctcc agcaggcagc ggtggtgatc ccgcagcagc gcagcgggga
    13681 ggacgtactc ccgggcgtga tcccagggac cacggagtag tgcacgcgtt cgacagggcg
    13741 ggagcgtccc ggccggcggc accgctcgat cggaaaacgc cggcccagtc gcggacccct
    13801 gtcgagccga ccccgatcac gagatatctt gatgtcgagc aatgttgcag acgtggagcg
    13861 gagcacccgg tgactgactc gaccatcatc tacacctaca cagacgaggc cccggccctg
    13921 gcgacgcatt cgttcctgcc ggtgatccag gcgtacgcct cgcaggccgg tgtgccggtc
    13981 acgacgcgcg acatctcgct ggccgggcgc atcatcgccc acttcccgga gtacctgaac
    14041 gaggaccagc gcatccccga cgcgctggcc gagctgggcg agctggccaa gacccccgcg
    14101 gccaacatcg tcaagctgcc gaacatctcg gcgtccatcc cgcagctgaa ggccgccgtc
    14161 gccgagctcc agggcaaggg ctacgcgctg ccggactacc cggacgaccc gaagaccgac
    14221 gaggagcgcg agatccgcgc ccgctacgac aaggtcaagg gctccgccgt caacccggtg
    14281 ctgcgtgagg gcaactccga ccgccgcgcc ccggcctcgg tgaagaacta cgccaagacc
    14341 cacccgcacc gcatgggcgc ctggaccgcc gagtccagga cgaacgtggc gacgatgagc
    14401 gagaacgact tcgccgccac cgagaagtcc acggtcgtcg ccgaggacgg cacgctccgc
    14461 ttcgagctgg tcggcgcgga cggcaccgcc accgagctgc gcgagccgct gaaggtcgtc
    14521 gcgggcgagg tcgtcgacgc agccgtgctg cgcgtcgccg cgctcaagga gttcctcgcc
    14581 gcgcaggtcg cccgcgccaa ggccgagggc gtgctgttct ccgtgcacct gaaggccacg
    14641 atgatgaagg tctccgaccc gatcatcttc ggccacgtgg tacgcgcctt cttcccgaag
    14701 accttcgcgc agtacggcga gacgctggcc gccgccggcc tgtccccgaa cgacggcctc
    14761 ggcaccatcc tggccggcct ggcgaacctg cccgagggcg acgcgatcaa ggcctccttc
    14821 gacgccgaac tggccgacgg cccggccctg gccatggtcg actcggacaa gggcatcacc
    14881 aacctgcacg tcccgtccga cgtgatcgtg gacgcctcca tgcccgcgat gatccgcacc
    14941 tccggccaca tgtggggccc ggacggccag gaggccgaca ccctcgcggt cctgccggac
    15001 cacagctact ccggcgtcta ccaggccgtc atcgaggact gccgcgccca cggcgccttc
    15061 gacccggcca ccatgggcac ggtgccgaac gtcggcctga tggcgcagaa ggccgaggag
    15121 tacggctccc acgacaagac cttcgagatc ccggccgacg gcacggtccg cctggtcgac
    15181 gccgcgggcg acgtcgtcct ggagcaggcc gtcgccaagg gcgacatctt ccgcgcctgc
    15241 cagaccaagg acgccccgat ccgcgactgg gtcaagctgg ccgtcacccg cgcccgcgcc
    15301 accggcgacc cggcggtgtt ctggctggac gagaaccgcg gccacgacgc ggtcctgatc
    15361 gagaaggtca aggcgtacct gcccgagcac gacaccgagg gcctggacat caagatcctc
    15421 tccccggtcg aggccaccaa gctgtcggtg gagcgcatcc gccgcggcga gaacaccatc
    15481 tcggtgaccg gcaacgtgct gcgtgactac ctgaccgacc tcttcccgat cctggagctg
    15541 ggcaccagcg ccaagatgct gtcggtcgtc ccgctgatgg cgggcggcgg cctgttcgag
    15601 acgggcgccg gcggctccgc gccgaagcac gtccagcagc tggtcaagga gaactacctg
    15661 cgctgggact ccctcggcga gttcttcgcc ctggtgccgt ccttcgagca gtacgccgag
    15721 gccaccggca acgcccgtgc caaggtcctc gccgacaccc tcgaccgcgc cacggcgacc
    15781 ttcctcaacg aggacaagtc cccgacccgt cgcgtcggcg gcatcgacaa ccgcggcagc
    15841 cacttctacc tgtccctgta ctgggcgcag gagctggccc ggcagaccga cgacgccgac
    15901 ctggccaagg tgttcgcgcc gttcgccgag tccctcgcgg ccgacgagca gaagatcgtc
    15961 ggcgagctgc tcgccgtcca gggcgagccg gccgacatcg gcggctacta ccaggtcgac
    16021 caggccaagg ccgacgcggt catgcgcccg tcggccacct ggaacgcgac gctcgcgtcc
    16081 ctgagctgac cgctcacggc ggccggtccg ccgtaccgca ctccgccccg gccgggtacc
    16141 tcccggccgg ggcgcagccg ttgccgagcc tcccggagcc gcgcgtgccc tccttcgaac
    16201 tgctccccgg cgaccccggc tcgcccgtcc tgctgcacgt gccgcactcg gcgcgggcga
    16261 tcccggcgga cgtgcgccgc gggatcgtcc tggacgacgc cgcactggag cgggagctgg
    16321 accacatcac ggacgcgcac accgccgaac tcgccgagcg ggcggccgag tcggccgggg
    16381 tgacgccgtg gcggttcgtg aaccggctgt cccggctggt cgtggacccg gagcggttcc
    16441 cggacgagcg cgaggagatg gcggccgtcg ggatgggcgc cgtctacacc cggaccacgc
    16501 accagggcga gctgcgacgg ccggacaccg atcccgaacc cctgctggag cgctggttcc
    16561 ggccgtacgc gcgcgccatg accgaggcgg tggcggaccg gctggcggcg accgggcggg
    16621 ccgtgatcat cgacgtgcac tcctacccga ccgcaccgct gccctacgag ctgcacgccg
    16681 cgggcccgcg tcccgcggtg tgcctgggca cggacgcgtt ccacacgccg ccgcggctgg
    16741 ccgaggccgc ccgcgaggcg ttcgcggcct gcggggagac ggggctggac agcccgttcg
    16801 ccgggacgta cgtacccctg gagttccacg gcggggacag ccgggtcggc gccctgatgg
    16861 tggagatccg ccgggacacc tacatggcgg agccgggcgg ggcggcgggg ccggggctgg
    16921 agcggctggc cggggcgctg gccgcgctcg tcgactccgt ctga
//
