LOCUS       reptomyces_RBGC_477282 17278 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_477282
VERSION     Streptomyces_RBGC_477282
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_900114955.1
  ORGANISM  GCF_900114955.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1437
                     /protein_domains="PF00135"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753327"
                     /pseudo=False
                     /translation="MTTTAPKAPTAPGVRSWWGIPYATAERYRRPVVADFAPDRPYDRK
                     GVVSVQPDSGDWLEADSGMGENCLNLNVWAPEQPAGTALPVAVYIHGGGFEYGANTQIT
                     SNASGLAASGRVVSVSVNYRLGALGALSLSQYGGRLAEVSNLFLQDVIAALTWVKRNIA
                     HFGGDPDQVTVYGHSAGAYSTFGLLGASSADGLYRRLAGFSGGPARSVPAWWAEELAHL
                     FVTELGVADNPEKLLDLDAVSLRDALRKVAPTDLGVRGGVDNKATGVVLDIGQPGAVVH
                     AHPMDVLASGAHRDVDVLLSMASDDMGWWVANDLDRFDPHTLDRVVDEVAGWRISRSRA
                     KKIVDAYDQGGRTPAEVRAAVMADYLFALPAARGALAHAAAGGNAHLLMIGPAEGAPAV
                     HGTEMYALVGQEQPGRSAEQAERDTRIRDIVLDFATGEQSRLWPAVTDKPTSGSVGNPP
                     FEATAHYQQTLGLWEGIDRP*"
     CDS             1501..2522
                     /protein_domains="PF13602"
                     /protein_domains="PF08240"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753328"
                     /pseudo=False
                     /translation="MSQPTAAGDAAPATMRAVVVTRPGGLDALQIQDVPVPVRKPGWVR
                     IRVKAFGVNESEVTTRKGESDAEVTYPRIPGIEGVGVVDAADEDSVLGPGRQVATMMGN
                     MGRSYDGAYAQYVTVPAAQVIPFETTLPWDVVGALPEMFQTAYGSLTRGLDLKAGQTLL
                     IRGGTSTVGLSAAAMAKDIGATVISTTRHAGRADELRAMGVDHPIVDDGHIAEKVRDLA
                     PQGVDAALELVGCTALPDTFGCVRVHGTVCFTGALGGAWTIPDFTPFMIPSGVRLTSYA
                     GEAADLPADVFAHQLQAIAEGRLKVPVAKVYQGLEQVRDAQADVESGTTPGKHVVVLDD
                     *"
     CDS             2715..3010
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753329"
                     /pseudo=False
                     /translation="LDPELAPVEEARGAVFPALSDEALPEIRRQIAEGSPGLDSEALTA
                     GGRVRVEERQVPGPEGEPDITVLILSPAEDRGPKGGILSLHGGGMIMGDAGTT*"
     CDS             3151..3482
                     /protein_domains="PF07859"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753330"
                     /pseudo=False
                     /translation="VLGERRGGPEVSQYAAPARADDLSRLPRTYIDTGSAEGFRDEILS
                     YAGRLAEAGVSVDPHMWGGGFHGFDMTVDHAAVSRASSATREEFIRPLTGEWCGNAQTA
                     KTAIAS*"
     CDS             complement(3514..4448)
                     /protein_domains="PF12833"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753331"
                     /pseudo=False
                     /translation="MVDRRHPDPSGSAAGPAVVPLYGFQPPVGTPYGLEVSTVEDFFTH
                     HDDWPWNPPRPGRATFHYLIAVTEGELRHDVDHVTRTVAPGQWLWVRPGHAQCWHPPGA
                     ARGPFILFEPDVLRPDIARLLAPLTAHEASAVLSPHPDDTAWLQQTALQLLDEHRTLGR
                     RPLDIHHALRRSLLESLLLRLANSPGIATIGTATAGAGRADRYGRFLDALELHFRELHH
                     AADYAELLGCSVRTLSRTARDATGKGVRELIDDRRLLEARRLLEAARWDARAVAVHLGF
                     TDAANFGRFFRDRTGLTPAAYAARETRTDA*"
     CDS             4581..4975
                     /protein_domains="PF04237"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753332"
                     /pseudo=False
                     /translation="MNGPALHKTAADCAEELPGAQLEHPFGPDWEVFKVRGKVFMLMTE
                     VPGRPVVILKADPGEAQALREQYRYITPGYHMNKKHWITLESGDGIDQELVRELVTDSY
                     RLVVAHLPKAEQPVDPHTYGTGTRAPR*"
     CDS             4973..5367
                     /protein_domains="PF04237"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753333"
                     /pseudo=False
                     /translation="VSAAGDRLQDTARRAALALPDVSHGYPFTPGLDVYKVAGKVFLIV
                     TDDPDEQIITVKCEPEHARALERGHASITPGRYLDKRHWISLGPGPRITERLVTDVVED
                     SYHLAVERLPRRDRPVPDELRDLPPSG*"
     CDS             5450..6762
                     /protein_domains="PF12002"
                     /protein_domains="PF16193"
                     /protein_domains="PF00004"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753334"
                     /pseudo=False
                     /translation="MEPTEVTLPLFREEPSRPLADRLRPTQLEDVVGQDHLLAPDAPLG
                     RMVAQQRLGSAILWGPPGVGKTTIARLLADAGNLAFEPVSATFSGVADLRKVFAAARSR
                     RGIGQGTLLFVDEIHRFNRAQQDSFLPYVEDGTVTLIGATTENPSFELNGALLSRTQVL
                     VLKRLDEAALSTLLDRAEQLTGHHLPLDDDARRALIAMADGDGRYLLNMAEQLQALPDT
                     ETTLDTAGLAHHIQQRAPLYDKAQEGHYNLISALHKSMRGSDPDAALYWLARMLDGGED
                     PLFVARRLVRFANEDIGMADPHAVQQALAAWDVYERLGSPEGELAIAQAVVHLATAPKS
                     IAVYRGFNAAHRSARHTGSLMPPAHILNAPTRLMKDLGYGRDYQYDPDTADGFSGDDYF
                     PDDMNRQTYYQPTRNGYEAQITERLRHWAALRARRQRG*"
     CDS             6859..6995
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753335"
                     /pseudo=False
                     /translation="MTDVSRIEKGQLERSEGDTLAAYVKALGGKLKIVADFGDESYVLG
                     *"
     CDS             7461..7645
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MITTSRPSGQSLDADSGQVGCGAYGVFRGGVGRVSAGSSRSEKWV
                     HVNALTPACRPCVVCL"
     CDS             7718..7950
                     /protein_domains="PF09957"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753336"
                     /pseudo=False
                     /translation="MSVTQIDLDDEALAEAMRLMGATTKKETVNAALRDYVARIRRLEA
                     AEKLSARGERGEFEQAAAAHEAEKRARRKAFE*"
     CDS             7948..8354
                     /protein_domains="PF01850"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753337"
                     /pseudo=False
                     /translation="VITYLVDTSALWHLFRTPGALRPWEGHIAAGVFHLCEPTRAEFLY
                     SATSPSHRDELAEELDALCLLSPVPKNAWRWVDTAQYKLTQKGQHRTAGAIDLLVCATA
                     VHHGHTVLHVDNDFATVAGVLKEVQQRDARA*"
     CDS             8837..9378
                     /protein_domains="PF00741"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753338"
                     /pseudo=False
                     /translation="MSSYPDDNVGNRAALPPASTRRDGAMAGTRGAGTVPLQPRRDGDG
                     GLAHVVETLLDKGLVLNADIMVSVAGVELLGIRLRAALASFETAAHYGLEFPSGTDTET
                     AAWRQARVAKETCPQCDKRAPVEQLLQEYCPWCGWRSAQARLAEQALAGPVPLDGSAAG
                     GDRASVEAGNEAARRDR*"
     CDS             9369..10303
                     /protein_domains="PF00741"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753339"
                     /pseudo=False
                     /translation="VTAEPSPLRPTRDPRVTLDDLVEVLLNKGAVLHLDLIVAVSDVPL
                     IGVSLRAAVAGMETMLEYGMMRNWDEATRAWAERSAARRTIDLRDGERVVSRMSGGHLL
                     TEGPNHTWRPGIVWLTDQRLAVVRDQPREVLWESDLGVVRGVRLAPEPTVGGEERLRVR
                     VALADGTEELLSAQDPERLHDHLTDACAGRLDNAFWHTSPAVEERPLAEGRLWFHEPRR
                     SGPLWRCGQGRLTGEALTWKSPMDSRPALVVPTAEITGVRRTAHGTSPAGDGEVLVLRA
                     RGWGEVLLAADDSAPWTQALNTAGSIPPAA*"
     CDS             10352..10665
                     /protein_domains="PF05121"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753340"
                     /pseudo=False
                     /translation="MPLTVDEKSLKHGVLSLVVTLVEVIQEALERQALRRINGGDLTLE
                     ESERLADALLELDEAMDQIKDDHGITSSVADLHRGLDEVVDDVVDKLVNPRRWAEEADA
                     *"
     CDS             10663..11531
                     /protein_domains="PF06386"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753341"
                     /pseudo=False
                     /translation="MTGHHALYVYALLRSETAATCEVTGLDGCPTRLVHAPGTGIAALV
                     HDAPATPYQGSDDQVRRWVRQQNEVVTTVWERTGSVLPMTFNVLVADESSDEPAPAGGS
                     AGGRKAAERLTEWIAERAADIDEQLRTLADRCELRVEIALDRRALGATPAPHADAASTH
                     RSAGMRRLLAKQEEQTARQTAERLADEVHAEVRGRLLALAEDLRDRGRTQQSPDETHVL
                     SVALLTRQEDIDTVGGVLSELQARQPAVRIRFLGPWPPYSFTELPDPPPTAAPLAGQRL
                     AGARSDPP*"
     CDS             complement(12102..12727)
                     /protein_domains="PF13460"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753342"
                     /pseudo=False
                     /translation="MNLLILGATGPTGRHVVDLALAAGDGVTVLARRPEALEDLADRVT
                     VVAGDATSHGDVAKAMVGQDAVVSALGRSTSIRADDLFTRAAAAVIGAAREQNVARLVW
                     LSSFGVGETYRSASLVQKIFYRTFLRNIYANKAISERAIRSSGLDWTLVYPTMLTKGPA
                     KGGYRADDRLPMKGNPTISRADVADFLHKAAHDPTWIHRDAVITD*"
     CDS             12818..13557
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753343"
                     /pseudo=False
                     /translation="MEASLQDPPPSGEPVAPSCQRHTERMAQVIELRGDVEFWARVGPL
                     AESDVGEWVHIAHDLDTWPGAREAARRQMRLGKVHRARKLYSPAVLADERDRDALREMA
                     ASGFRIRIATAPLPQGTVIIDRRTMILTDPASSAPGAQQPRTYTMSASPALIGGTYALF
                     EAAWESAADLSTFLDPQRPRMDAATSKVLRALVSGATDEVAARELGMSLRTYRRRVAEL
                     LVSLDAASRFQAGVRAGELGLTRG*"
     CDS             13705..14363
                     /protein_domains="PF00440"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753344"
                     /pseudo=False
                     /translation="VSKPVAREPLRRNSRSNRARILATAREELGRNPDVTLEELARAAG
                     VVRRTLFGHFPGRAALLEALAEEAAETLRNTVEAGPESGDPAEPAERALARFVLRMWPV
                     GDRYRMLLALARRDLGSERVAEVLAPAREAATAILERGQRDGVFHSRLPPAVQSAGLEA
                     MHVALLESVNTGALEDDGHRIATTTLIAAGVPEERASAVVEEVASALATALPADGA*"
     CDS             complement(14607..15460)
                     /protein_domains="PF00440"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753345"
                     /pseudo=False
                     /translation="VTSRPARTPTARPRPSPPQRHETPPPPRPAAASAQRRDARATRAR
                     ILDAARRELARDPDSRLENIAAAAGVARRTVYVHFAGRAALVEGLAAEAAEAIRRAVAD
                     APAETPDAAADLARCVLTVWPVGDRYRTLIRLARGQDLAPARVDELLSPARDLVTRVLT
                     HGHRQGVFQTTLPPAPLTRAVEAHLLGLLDCVNRGLWSDDGTGAATAALITAGVAPDTV
                     TAKVAHVRKTGSPQRPARNPDPVRHPGPGGHHGVRHPRRRLRPPAPDDLTRPGDGRIDE
                     VGR*"
     CDS             15594..17278
                     /protein_domains="PF07690"
                     /protein_domains="TIGR00711"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6753346"
                     /pseudo=False
                     /translation="MPFLANTPVEKMTGPYARRWWALLVLCLSLLIVVMANTSLIVAAP
                     DMTTDLGLSSSDLQWVVDGYTVPYAALMLVLGAIGDKYSRRGALVLGLLIFAGGSVMGS
                     MVDETALVIAARAIMGVGAAVVMPATLSLLVATFPRSERVKAITVWTATSGLAIAVGPL
                     VAGWLLEDHAWGSTFLINVPIAVVAVVGALALVPPSKAEGMGRIDYVGGLLSIVSVGSL
                     VYAAIEGPHFGWGAGPVTAAVVAGVGLLAFVAWELRHPHPMLDVRKFALRPFSGSMLAV
                     LFFFFGTFGAIYYSTQFLQFVLGYDALETGVRLLPLAGAVFVGAMVTGKLTPKLGVKAM
                     VVTGMLVGTAGVFLLTQIDKGSAYGDFLAPMMMLGFAIGLSVSPATDTIMDSFPESELG
                     VGGGANDTALELGGALGIAVLGSLLGTAYRDELTDLVGNRLPGEAMEVAQDSVGGGLAV
                     AERVAQDPSAGPQQAQAVVDAVHQAFAHGVAQTSLIGGIIMAAGTLIVLAVLPGRRGFA
                     ETEKNAEPVAGTTANETATADEAAVDEATADEAAAERERAGSIR*"
ORIGIN
        1 atgactacga ccgcgcccaa ggccccgact gcaccagggg tgcggtcctg gtggggaatc
       61 ccgtacgcca ccgccgagcg gtatcgccgc cccgtggtcg cggacttcgc tccggaccga
      121 ccctatgacc gcaagggcgt cgtctctgtc cagcccgaca gcggcgactg gctggaagcg
      181 gacagcggga tgggcgagaa ctgtctgaac ctgaacgtgt gggctcccga gcagccggcc
      241 gggacggcgc ttccggtggc cgtgtacatc cacggcggcg gattcgagta cggcgcgaac
      301 acgcagatca cgtcgaacgc ctccggtctc gccgcgtcgg ggcgcgtggt gagcgtgtcg
      361 gtcaactacc ggctcggcgc cctgggcgcg ctctcgctct cgcagtacgg cgggcggctc
      421 gccgaggtca gcaacctttt cctgcaggac gtcatcgccg cgctgacctg ggtcaagcgg
      481 aacatcgccc acttcggcgg cgaccccgac caggtcacgg tctacggcca cagcgccggc
      541 gcctactcca ccttcggtct gctcggcgcc tcctccgccg acggcctgta ccggcggctg
      601 gccgggttct ccggcgggcc cgctcgtagc gtcccggcct ggtgggccga ggagctcgcg
      661 cacctgttcg tcaccgaact cggggtagcg gacaacccgg agaagctgct cgacctcgac
      721 gcggtctccc tgagggacgc cctgcgtaag gtcgccccga cggacctcgg agtccgcggc
      781 ggggtggaca acaaggccac cggcgtcgtc ctggacatcg ggcagcccgg cgcggtggtg
      841 cacgcccatc ccatggacgt cctcgcctcg ggggcgcacc gcgatgtcga cgtgctgctg
      901 agcatggcga gtgacgacat ggggtggtgg gtggcgaacg acctcgaccg tttcgacccg
      961 cacaccctcg accgcgtcgt cgacgaggtc gcggggtggc gtatttcccg ctcccgcgca
     1021 aagaagatcg tcgacgccta cgaccagggc ggccgtaccc cggccgaggt ccgcgccgcg
     1081 gtcatggcgg actacctctt cgcactcccg gccgcccgcg gcgccctggc gcacgccgcc
     1141 gcgggcggca acgcccatct cctgatgatc gggcccgccg agggcgcacc cgccgtgcac
     1201 ggcaccgaga tgtacgccct ggtcggccag gaacagccgg gccgcagcgc cgaacaggcc
     1261 gagcgtgaca cgcggatccg cgacatcgtg ctcgacttcg ccaccggtga acagtcccgt
     1321 ctgtggcccg ctgtcacgga caaacccacc tcgggaagcg tcggcaaccc gcccttcgaa
     1381 gccacggccc actaccagca gaccctcggc ctgtgggagg gcatcgaccg tccttgacgg
     1441 ctggcgggac gacatccgga acagcgcacc agggggcgaa acagagtgag gaactcggta
     1501 tgagccaacc gacagcagcc ggcgacgccg caccggcgac gatgcgggcc gtcgtcgtca
     1561 cccggcccgg cggcctggac gcacttcaga tccaggatgt gccggtgccg gtacgcaagc
     1621 ccggctgggt gcggatcagg gtgaaggcgt tcggcgtcaa cgagtccgag gtcaccaccc
     1681 gcaagggcga gtccgacgcg gaggtcacct acccgcggat ccccggcatc gaaggcgtcg
     1741 gcgtggtcga tgcggccgac gaggacagcg tcctcggccc gggtcggcag gtggccacga
     1801 tgatgggcaa catgggccgc tcgtacgacg gcgcgtacgc ccagtacgtg accgtccccg
     1861 cggcacaggt catcccgttc gagaccaccc tgccgtggga cgtcgtcggc gccctgcccg
     1921 agatgttcca gaccgcctac ggatccctga cccgtggcct ggacctcaag gccggacaga
     1981 cgctgctgat ccgcggcggc acctccacgg tcgggctgag cgcggcggcg atggccaagg
     2041 acatcggcgc cactgtcatc tccaccacgc gtcacgccgg gcgtgccgac gaactgcggg
     2101 ccatgggtgt cgaccatccg atcgtggacg acggacacat cgccgagaag gtccgggacc
     2161 tcgcaccgca gggcgtggac gccgcgctgg aactggtggg ctgcacagcc ctgccggaca
     2221 ccttcggatg cgtgcgcgtg cacggcaccg tctgcttcac cggcgccctg ggcggcgcgt
     2281 ggacgatccc cgacttcacc ccgttcatga tccccagcgg ggtgcgactg accagttacg
     2341 cgggcgaggc cgccgacctc ccggccgacg tcttcgccca tcaactccag gccattgcgg
     2401 agggacggct caaggtcccg gtcgcgaagg tctaccaggg cctggaacag gtccgtgacg
     2461 cccaggccga cgtcgagtcc ggcaccacgc cgggcaagca cgtcgtcgtc ctggacgact
     2521 gagaactgat cacgggacgc gacgaggtca tcgcacacct cgactcgatc tgctcgcacc
     2581 cgcacgtcgt tcgcagtgag tccttcagcc cggcggagag cgcctccgct ccccgtcgtt
     2641 gtttccgaag gagagaacag atgacggacc agacagcagc agactctttc ggtgccacga
     2701 ccatccggcc ccgttggacc cggaactcgc gcccgtcgag gaggcgcggg gagccgtctt
     2761 tccggccctg tcggacgagg ccctgccaga gatccgacgg cagatcgcgg agggttctcc
     2821 cgggttggat tcggaggctc tgacggcggg cggcagagtg cgggtggagg agcgccaggt
     2881 accggggccg gaaggcgagc cggacatcac ggtgctgatc ctcagccccg ccgaggaccg
     2941 aggccccaag ggaggcatcc tcagcctcca cgggggcggg atgatcatgg gggacgccgg
     3001 gaccacgtga gtcatctcct tccccatgtg atcgagggga gtgcggtcgt cgtgtcggtc
     3061 gaataccggc tggcgccgga tcaccccgat cccacgcctt tcgcccgctc agccaccaaa
     3121 ttctgagcaa cctgtatgcg tggacctccg tgctgggtga gcggcggggc ggtccggagg
     3181 tgtcgcagta cgccgcgccg gcccgcgccg atgatctcag ccggctgccg cgcacctaca
     3241 tcgacaccgg ctcggccgag gggttccgcg acgagatcct gagctacgcc ggccgcctgg
     3301 ccgaggcggg agtgagcgtc gatccgcaca tgtggggcgg gggcttccac gggttcgaca
     3361 tgacggtgga tcatgcggct gtgtcgcgcg cttccagcgc gacccgtgag gagttcatcc
     3421 ggcccttgac aggtgagtgg tgcggcaacg cgcagactgc gaagacagcc attgcctcct
     3481 gacgggcaag cccggcggtc accgcgtttc cgtcaagcgt cggtcctcgt ttcgcgggcc
     3541 gcgtaggcgg ccggggtgag gccggtgcgg tcgcggaaga agcggccgaa gttcgcggcg
     3601 tcggtgaagc cgaggtggac ggccacggcc cgggcgtccc accgggcagc ttccagcagg
     3661 cgccgggctt ccaggaggcg ccggtcgtcg atcagttcgc gtactccctt gccggtggcg
     3721 tcccgggcgg tgcggctgag ggtgcggacc gagcagccga gcaactcggc gtagtccgcg
     3781 gcgtggtgca gttcgcggaa gtgcagctcc agggcgtcca ggaagcgtcc gtaccggtcg
     3841 gcacggccgg cgccggccgt ggccgttccg atggtggcga tgccagggga gttggccagg
     3901 cgcagcagca gcgattcgag caggctgcgg cgcagggcgt ggtggatgtc gagggggcgg
     3961 cgccccagtg tgcggtgttc gtccaggagt tggagtgccg tctgctggag ccatgcggtg
     4021 tcgtcggggt gcgggctgag cacggcggag gcctcgtgcg cggtgagcgg ggccaggagg
     4081 cgggcgatgt cgggcctcag cacgtccggt tcgaacagga tgaacgggcc gcgggccgcg
     4141 ccgggcggat gccagcactg tgcgtgcccg ggacgcaccc acagccactg gccgggggcg
     4201 acggtccgcg tgacgtggtc gacgtcgtgc cgcagctcac cctcggtgac cgcgatgagg
     4261 tagtggaagg tggcacggcc cggacggggc gggttccacg gccagtcgtc gtggtgggtg
     4321 aagaagtcct cgacggtgct cacttcaagg ccgtagggag taccgaccgg gggctggaaa
     4381 ccgtacagcg gtaccacagc cggaccggcc gcgcttccgc tcgggtcagg gtgtcgcctg
     4441 tcgaccatca cgtgtccgca gcctactgcc tttctggttg gctgcggcgg aaggatggga
     4501 cgtgccgccg cgcccgcgcg gcgtgccctc cacgtctttc gatgccacag tccgtcacca
     4561 cttgaggaag cgcacgccca tgaacggacc ggccctgcac aagaccgccg ccgactgcgc
     4621 ggaggagctc cccggagctc agctggaaca ccctttcggt cctgattggg aggtcttcaa
     4681 ggtgcgcggc aaggtgttca tgctgatgac cgaagtcccg gggcggcccg tggtgatcct
     4741 caaggcggat cccggtgagg ctcaggccct gcgggagcag taccgctaca tcacccccgg
     4801 ctatcacatg aacaagaagc actggatcac cctggagagc ggagacggca tcgaccaaga
     4861 gctcgtcagg gagctcgtca ccgactccta ccggctcgtc gtcgcccacc tgcccaaggc
     4921 cgagcagccc gtcgacccgc acacctacgg caccggcacg cgggcgcccc ggtgagcgcg
     4981 gccggtgacc ggctccagga caccgcccgc cgggcggccc tggccctccc cgacgtcagc
     5041 cacggctacc ccttcacccc cggactcgac gtatacaagg tcgcgggcaa ggtgttcctg
     5101 atcgtcaccg acgacccgga cgaacagatc atcacggtca agtgcgaacc cgagcacgcg
     5161 cgggcactgg agcgcggcca cgcatcgatc acaccgggcc gctatctcga caaacggcac
     5221 tggatctcac tggggccggg accccgcatc accgagcggc tggtcaccga cgtggtcgag
     5281 gactcctacc acctggccgt cgagcggctg ccgcgacgcg accgcccggt gcccgatgaa
     5341 ctccgcgacc ttccccctag cggctgagcc gacgcctgtc agtgccccgt gcaaggctcg
     5401 tcatgtccgc acacgtacgc acacgtccgc ctgcgacccg agagacggat ggaaccgacc
     5461 gaagtgaccc tcccgctctt ccgcgaggag ccctcccggc ccctcgccga ccgcctgcgc
     5521 cccacccagc tggaagatgt cgtcgggcag gaccacctcc ttgccccgga cgccccgctc
     5581 ggccgcatgg tcgcccagca gcgcctcggc tccgccatcc tgtggggccc tcccggcgtc
     5641 gggaagacca ccatcgcccg gctcctcgcg gacgccggca acctggcctt cgagccagtg
     5701 tcggccacct tctccggcgt cgccgatctg cgcaaggtct tcgccgccgc acgaagccga
     5761 cgtggcatcg gccagggcac cctgctgttc gtcgacgaga tccaccgctt caaccgcgcc
     5821 cagcaggaca gcttcctgcc ctacgtcgag gacggcaccg tcaccctgat cggcgccacc
     5881 acggagaacc cgagtttcga actcaacggc gccctcctct cccgcaccca ggtcctcgtc
     5941 ctcaaacgcc tcgacgaagc cgcactgtcc acgctcctcg accgcgccga gcagctcacc
     6001 ggccaccatc tgcccctgga cgacgacgcc cgccgcgcac tgatcgccat ggccgacggc
     6061 gacggccgct acctcctcaa catggccgaa cagctccaag ccctcccgga caccgaaacc
     6121 accctggaca ccgccgggct cgcccatcac atccagcagc gcgccccgct gtacgacaag
     6181 gcgcaggagg gccactacaa cctgatctcc gcgctgcaca agtcgatgcg cggctccgac
     6241 ccggacgcgg ccctgtactg gctcgcccgc atgctcgacg gcggcgagga cccgctgttc
     6301 gtcgcccgcc gcctggtccg cttcgcgaac gaggacatcg gcatggccga cccgcacgcc
     6361 gtccagcagg ccctcgccgc ctgggacgtg tacgagcgac tcggctcccc cgagggtgag
     6421 ttggcgatcg cccaggccgt cgtccacctc gccaccgccc ccaagtccat cgccgtctac
     6481 cgcggcttca acgccgcaca ccgatcagcc cggcacaccg gttcactcat gccacccgcc
     6541 cacatcctca acgccccgac ccggctgatg aaagaccttg gctacggcag ggactaccag
     6601 tacgacccgg acacagccga cggcttctcc ggtgacgact acttccctga cgacatgaat
     6661 cgccagacgt actaccagcc cacccgcaac ggctacgaag cccagatcac cgagcgcctg
     6721 cgccactggg ccgcgctgcg cgcccgccgg caacgcggct gaacggccgc gcccgcgacg
     6781 tctccgcgag ggccctccca ggcggagcag gcgtacgcgg agcatctgaa gcgaatcgat
     6841 ggagaggacg gggcactatg actgacgtct cgcgcatcga gaagggccaa ctggagcgca
     6901 gtgagggcga caccctcgct gcctacgtca aggcgctcgg cggcaagctg aagatcgtcg
     6961 ctgacttcgg cgatgagagc tacgtcctcg gctgacgcga tcgacgcgcc gctacccagg
     7021 tcgatgcgca gtccggtgga cgggatcgca tccgacgtca gggatgatgc cccacccggg
     7081 tctgggatgg agcatcatcg cgtcggtaag agactccgct gcgcgaaggt tccagcccct
     7141 cggccttgct gggcggacgc ggctgatgtt gtggaaggcg cccaactcat cgacccccag
     7201 gggccattga ggggccacaa ggacagaaac aggccgacaa gcactgcaca gggctgaagc
     7261 agatcagcac gtctgacctg caagaacggc gtgaatcggc acggatcggc aaggaccgcc
     7321 aagatcctca atggactcat aatccgtcgg ccgtgggttc gagtcccacc cgccccacca
     7381 ctcgctacgc gaggagaaac cgtctggcca ggcgttttcc tggtcagggc gagagtctga
     7441 gggtcctggc ggccccgttg tgatcacgac ttctcgaccg tctggacaaa gtctggacgc
     7501 cgattccggt caagtcggat gtggtgctta tggggtgttt cgtggcggcg tcggacgagt
     7561 ctccgctggc tcgtcccgca gtgagaagtg ggtccatgtg aacgccctga cgccggcgtg
     7621 ccgcccctgc gtggtctgtt tgtgattgat ggttggtcgc gctcgatgtt ggtgacgtat
     7681 cctgagcgca tacatcgtgg acatgggagg tgtgcgatgt ccgtcacgca gattgatctc
     7741 gacgacgagg cactggccga ggccatgcgg ctcatgggtg ccacgacgaa gaaggagacc
     7801 gtcaacgcgg cccttcggga ctacgtagcg cggatcagga ggcttgaggc cgcggagaag
     7861 ctgtccgcgc gaggtgagcg cggcgagttt gagcaggccg cagcggcgca tgaagccgag
     7921 aagcgcgcgc ggcgcaaggc cttcgagtga tcacgtatct ggtcgacacc tcggctctgt
     7981 ggcatctgtt ccgtacccca ggtgcgctgc gcccctggga gggacacatc gccgccgggg
     8041 tgttccacct ctgtgagccg acacgtgccg aattccttta ctcggcgacc agcccgtctc
     8101 accgagatga gctggccgag gaactggacg cgctctgtct gctctccccg gttccgaaga
     8161 acgcttggcg gtgggtcgac accgcccagt acaaactgac ccagaagggc cagcatcgga
     8221 cggcgggagc gatcgacctg ttggtgtgtg cgacagctgt acaccatggg cacaccgtcc
     8281 tccacgtgga caatgacttc gcgacggtgg ccggagtcct caaggaagtt cagcagcgag
     8341 acgcacgagc ctgatctccg gaggcgggaa cgcgtctgtc ggcttatggc ctcggtgatc
     8401 gatgtctccg gggtgcatca ctacgaccta tccccgtata cgcggagacg gctccgtcat
     8461 caagatgtac tcgcggatgc tcccgtcgtc ggcctcgtgc acgcggggac ggctcgtgcg
     8521 ctgatcgttg aggctcccgg aggggctcgc tctcccatgc ctttgagtcg ctgtaggaga
     8581 atccgctgcg tgccagtgca ggagacgctg gctgggcgcg gggaaaggcc cgtactgaaa
     8641 cggccgtaga tcgcaccacg gagtcgcccc gcagtgcctc acggtttcgg aaggcttcct
     8701 cgctgatgcg caccgtgagg gtcgggctgc ccggtgtcgg taaggcgcgc aggccgtcgc
     8761 gtaccccgcg ccaggatggc cgccctccgc cgtgtcgggt gtgtaagtca cgtgagggcg
     8821 gatacttgca caggcatgag cagctatccg gacgacaacg tgggcaaccg ggccgcctta
     8881 ccgcccgcaa gcacacgccg cgatggggcg atggccggaa cgcgaggcgc gggaaccgtt
     8941 ccgctgcagc ccagacggga cggcgacggg ggtctggccc atgtcgtgga gaccctgctg
     9001 gacaaaggac tggtcctcaa cgccgacatc atggtgtcgg tggcgggggt ggaactgctc
     9061 ggcatccgtc tgcgcgccgc cctggcctcg ttcgagacgg ccgctcacta cgggctggag
     9121 ttcccctccg gtacggacac ggagacggcc gcctggcggc aggcgcgggt ggcgaaggag
     9181 acatgccctc agtgcgacaa acgtgctccc gtcgagcaac tgctgcagga gtactgtcct
     9241 tggtgcggtt ggcgcagtgc ccaggcccgc ctggcggagc aagcccttgc gggtcccgtc
     9301 cctctcgacg gctctgccgc cggcggcgac cgcgcgagcg tggaggctgg gaacgaggcg
     9361 gcccggcgtg accgctgagc catcgcccct gcgtccgacg cgtgaccccc gggtgacact
     9421 ggacgacctg gtcgaggtcc tgctgaacaa gggcgcggtc ctgcacctgg acctcattgt
     9481 cgccgtgtcg gacgtcccgt tgatcggggt cagccttcgg gcggccgtcg caggtatgga
     9541 gacgatgctc gagtacggca tgatgcggaa ctgggacgag gcgacccggg cctgggccga
     9601 acggtccgcc gcacgccgca cgatcgacct gcgggacggc gaaagagtcg tcagccgcat
     9661 gagcggtggg cacctgctga cagaggggcc gaaccacacg tggcggcccg gcatcgtctg
     9721 gttgaccgac cagcggctgg ccgtggtgcg ggaccagcct cgggaagtcc tgtgggagag
     9781 cgatctcggc gtcgtccggg gtgtccgact cgccccggag cccacggtgg gcggcgagga
     9841 acgcctgcgg gtgcgggtgg cgctggccga cggtacggag gaactgctgt cggcccagga
     9901 ccccgagcgg ctgcacgacc atctcaccga cgcgtgcgcg ggccgtctgg acaacgcgtt
     9961 ctggcacacg tcgccggccg tcgaggagcg gccgctggcg gaggggcggc tgtggttcca
    10021 cgagccgcgc cgcagcggcc cgttgtggcg ctgcgggcag ggacggctca ccggtgaggc
    10081 cctgacctgg aagtcgccca tggattcccg gcccgccctg gtcgtaccca ccgcggagat
    10141 caccggtgtg cgtcgtacgg cgcacgggac cagccccgcc ggggacggcg aagtgctcgt
    10201 cctacgtgcc agggggtggg gcgaagtgct gctggccgca gacgactcgg cgccttggac
    10261 gcaggcgctg aacacggcgg ggtccatacc gccggccgca tgaccgtcgt acgaccatgc
    10321 ggcgaaccgc gacacagaaa ggtggcagtc atgcccctga ccgtcgacga gaaaagcctc
    10381 aaacacggcg tgttgtctct ggtggtcacg ctggtggagg tcatccagga ggcgttggaa
    10441 cgccaggctc tgcgccgtat caacggaggc gacctgacgt tggaggagag cgagcgcctg
    10501 gccgacgccc tgctggaact ggatgaggcg atggaccaga tcaaggacga ccacggcatc
    10561 acttcctccg tcgcggacct gcaccgggga ctggacgagg tggtcgacga cgtggtcgac
    10621 aaactcgtca acccccggcg ctgggccgag gaggccgacg catgaccggg caccacgccc
    10681 tgtacgtgta cgccctactc cgttcggaga cagcggccac ctgtgaggtc accggtctcg
    10741 acgggtgtcc cacacggctc gtacacgccc cgggcacagg catcgcggcc ctggtgcacg
    10801 atgcccccgc caccccgtac cagggcagtg acgaccaggt ccgccgctgg gtgaggcagc
    10861 agaacgaggt cgtcaccacc gtgtgggaac gaaccggcag tgtcctgccc atgaccttca
    10921 atgtcctggt cgccgatgag tcgtccgatg agccggcccc ggcgggcggg tccgcaggcg
    10981 ggcggaaggc ggccgagcga ctgacggaat ggatcgccga acgggcggcc gacatcgacg
    11041 aacagctacg caccctggct gaccggtgcg aactgcgcgt ggagatagcc ctggaccgca
    11101 gagccctcgg cgccacaccg gccccgcacg cagacgcagc ctcgacgcac cgctcggcgg
    11161 gcatgcgccg gctcctcgcc aaacaggagg aacagaccgc caggcagacg gccgagcggc
    11221 tggccgacga ggtgcacgcg gaggtccgcg gcaggctgct cgccctcgcg gaagacctgc
    11281 gtgaccgcgg ccgcacccag caatccccgg acgagacaca cgtgctgtca gtggccctcc
    11341 tcacccggca ggaggacatc gacaccgtgg gtggagtcct gagcgaactc caggcacgcc
    11401 aacccgccgt gcgtatccgc tttttgggcc cctggcctcc gtattccttc actgaactgc
    11461 cggatccccc gccaaccgca gccccgctcg cggggcagcg gttggccggc gcacgctctg
    11521 atccgccgtg atcaacgaat cccgaccgga tcgacgccac gccggaggtg catgccgccg
    11581 gcatcggatg ccgacggcgg ccggggcgtc gctcatgcac cgggctccgc gtcgctcatg
    11641 caccgcgggc acctcagccg gcgggtccat cgcgacacca cgccgtcagg gcggcagtcg
    11701 ttgccgcaag gtttccctgc cgacaacgca tcgtgcagtc ggcctcgacc cgcctcctca
    11761 ctgtgcggcg accgctctgg ccaccgggcc gcgccgagtg ctgcgggcaa agtcaggccg
    11821 ccgacgccct cggtccggcg aacccacggt gaacctcgat cgccgacatc accgccgagt
    11881 tctacggctt cggtttcgcc atcgacgtga tccgcgaggc actgcgcccc gaggaccaca
    11941 tcctggtcgt cacgaaggtc ggcgccgacc ccgaccccac cgcgcgaacg ccgcggccga
    12001 cccgggggcc tggcccgggg acccggtctg gggaccggtc tggggacccg gcctagggac
    12061 cggtctgggg cgctgtcctg ccgaatgccg ggcgctgggt tcagtccgtg atgacggcgt
    12121 cgcggtggat ccaggtgggg tcgtgggccg ccttgtgcag gaagtcggcg acgtccgcgc
    12181 ggctgatcgt cgggttgccc ttcatcggga gacggtcgtc ggcgcgatag ccgcccttgg
    12241 cggggccctt ggtcagcatg gtcgggtaga ccagcgtcca gtccaggccg ctggagcgga
    12301 tcgcccgctc ggagatcgcc ttgttcgcgt agatgttccg gaggaaggtg cggtagaaga
    12361 tcttctgtac gaggctcgcc gagcggtagg tctcacccac cccgaacgag gacagccaca
    12421 ccagccgggc gacgttctgt tcccgcgccg cgccgatcac ggccgccgcg gcgcgggtga
    12481 acaggtcgtc ggcccggatc gaggtgctcc tgccgagcgc ggagacgacg gcgtcctgcc
    12541 cgaccatggc tttcgcgacg tcaccgtgcg aggtcgcgtc cccggcgacc acggtcaccc
    12601 ggtccgccag gtcctccagt gcttccggcc tgcgagccag gacggtgacc ccgtcgcccg
    12661 ccgcgagggc caggtcgacg acatggcggc cggtgggacc ggtcgcaccg aggatcagga
    12721 gattcatggg agcgtccttc gtctgaggat cggaagagcg gggtgacgac tcgagggtcg
    12781 gggtgcgggg cgacggccgg gcggaacctg ccgttcatgg aggcgagcct gcaagacccg
    12841 cccccctccg gcgagcccgt ggcaccttcc tgccaacggc atactgaacg catggcacag
    12901 gtcatcgaac tccgcggtga tgtcgagttc tgggcccggg tcgggcccct ggcggagtcg
    12961 gacgtcgggg aatgggttca catcgcccac gatctcgaca cctggcccgg agcccgtgag
    13021 gccgcccgcc gccagatgcg cctcggcaag gtgcaccggg cgcgcaagct gtacagcccc
    13081 gccgttctcg ccgacgagcg cgaccgggac gccctgcggg agatggccgc gtccggcttt
    13141 cggatccgga tcgccacggc ccccctgccg cagggcaccg tcatcatcga ccggcggacc
    13201 atgatcctca ccgacccggc gtcctccgcg ccgggcgccc agcagccgcg gacatacacg
    13261 atgagcgcct cgccggccct gatcggcggc acctacgcgc tcttcgaggc cgcctgggag
    13321 agcgcggccg acctgtccac cttcctcgat ccgcagcggc cccgcatgga cgccgctacc
    13381 tccaaggtcc tgcgcgcact ggtctccggc gccaccgacg aggtggccgc acgcgagctg
    13441 ggcatgtcgc tgcgtaccta ccgccgccgg gtcgcggaac tgctcgtcag cctggacgcg
    13501 gcctcacgtt tccaggcggg cgtacgggcg ggggagttgg gcctgacccg cggatgatcg
    13561 gcgccgggtc ggcggtgagg cagcgggggt gggcggtgtg ttccgcgtgt ggccggtggg
    13621 cgcgcggcgg gagatggggg cttcggcacg gcgtgacaaa atagggggcc gttcgtccgt
    13681 cctccgatgc tgcgaggttc tccgtgagca agcccgtggc ccgcgagccg ttgcgccgta
    13741 attcgcggtc caaccgggcg cgcatcctgg ccacggcccg tgaggagctg gggcggaacc
    13801 ccgatgtcac gctggaggag ctggcgcggg ccgccggcgt cgtccggcgc accctcttcg
    13861 ggcacttccc ggggcgggcc gcgctgctgg aggcgctcgc cgaggaagcc gccgagacgt
    13921 tgcggaacac ggtcgaggcc gggccggagt cgggggatcc ggcggagccg gccgagcggg
    13981 cgctggcgcg gttcgtgctc cggatgtggc ccgtgggcga ccgctaccgg atgctgctgg
    14041 cgctcgcccg gcgggacctc ggctccgagc gcgtcgccga ggtgctcgcg ccggcccgcg
    14101 aggccgccac ggcgatcctg gaacgcgggc agcgggacgg cgtcttccac tcccgtctgc
    14161 cgccggccgt gcagagcgcc ggcctggagg cgatgcacgt cgcgctcctg gagtccgtca
    14221 acaccggtgc gctggaggac gacgggcacc ggatcgccac gaccaccctc atcgcggccg
    14281 gagtgccgga ggagcgggcg agtgcggtgg tcgaggaggt cgcgtcggcg ctcgccacgg
    14341 cacttccggc ggacggcgcc tgacgcctct caggccgaac cgttcgcgac gacgcccggt
    14401 ggtgcccccg gcgtcgtcgc ggcggtaggt gaccgacttg ccggagaagc gccacgccgt
    14461 gaggccctgc tccctggtgg tgaccgagcg cagccggagg ccgccgagac ggtcttcgtc
    14521 gtggtgacct cgaagccgag cgtggtcagg acgcgggcgc ggatccggcc ggagccgtag
    14581 ccctgggtcg gttccaggct cgctgtcatc gtccgacttc atcaatccgg ccatctccag
    14641 gacgagttag gtcatcggga gcgggcgggc ggagccgtcg gcggggatgt cgcacaccgt
    14701 gatgtccacc cggtccaggg tggcgtacgg ggtcggggtt tcgggcgggg cgctggggcg
    14761 acccggtctt ccgtacgtgc gcgaccttcg cggtgacggt gtcgggggcg actccggcgg
    14821 tgatgagggc ggcggtggcg gcgccggtgc cgtcgtcgga ccagaggccg cggttgacgc
    14881 agtcgagcag gcccagcaga tgggcctcga cggcccgggt gagcggggcg ggcgggaggg
    14941 tggtctggaa gacgccctgc cggtggccgt gtgtgagcac cctcgtgacc aagtcgcggg
    15001 cgggggacag cagttcgtcg actcgggcgg gggcgaggtc ctggccgcgc gccagccgga
    15061 tgagggtgcg gtagcggtcg ccgacgggcc acacggtgag gacgcatcgc gccaggtcgg
    15121 cggcggcgtc gggggtctcg gcgggggcgt ccgcgacggc ccgccggatc gcctccgcgg
    15181 cctcggcggc caggccctcg acgagcgcgg cccggccggc gaagtggacg tagacggtgc
    15241 gccgggccac accggcggca gcggcgatgt tctccaggcg gctgtcgggg tcgcgggcca
    15301 gctcccgccg ggccgcgtcg aggatccggg cgcgggtggc ccgcgcgtcc cgccgctgcg
    15361 ccgaggccgc ggccggacgg ggaggaggtg gcgtctcgtg gcgctgtggc ggagacggcc
    15421 tcggcctcgc cgtcggtgtt cgtgctggtc ggctggtcac gtcggtacct cgggggtggg
    15481 tgggaggagg gcgcatcgcg atatttgcac agcagtgggc aataaactag tctgcacatc
    15541 gatgggcaat taagtgattc cgctcgtcgt acccgtcctc taggagctac cgatgccctt
    15601 cctcgcgaac acccccgtgg agaagatgac cgggccgtac gcgcggcgct ggtgggcgct
    15661 gctcgtgctg tgcctgagcc tgttgatcgt ggtgatggcg aacacgtcgc tgatcgtggc
    15721 cgcccccgac atgaccaccg acctgggtct gagcagcagt gatctgcagt gggtcgtcga
    15781 cggctacacc gttccgtacg cggcgttgat gctggtgctg ggcgcgatcg gcgacaagta
    15841 cagtcggcgc ggtgcgctgg tgctgggtct gctgatcttc gccggcggtt cggtgatggg
    15901 gagcatggtc gacgagaccg cgctggtcat cgcggcccgc gcgatcatgg gtgtcggtgc
    15961 cgcggtcgtg atgccggcca cgctgtcatt gctggtcgcg accttcccgc ggagcgagcg
    16021 cgtcaaggcc atcaccgtgt ggaccgcgac ctcgggcctc gcgatagccg tcgggccgct
    16081 ggtcgccggc tggctgctgg aggaccacgc ctggggctcg accttcctga tcaacgtgcc
    16141 gatcgccgtc gtcgccgtgg tcggcgcgct cgccctggtg ccgccgtcca aggcggaggg
    16201 catgggccgg atcgactacg tcggtggtct gctgtcgatc gtctcggtcg gctccctggt
    16261 gtacgcggcc atcgagggcc cgcacttcgg ctggggcgcc ggtcccgtca ccgcggccgt
    16321 ggtcgcgggt gtcggtctgc tcgccttcgt cgcctgggag ttgcgtcacc cgcacccgat
    16381 gctggacgtt cgcaagttcg cgctgcggcc cttcagcggc tcgatgctcg cggtgctgtt
    16441 cttcttcttc ggcacgttcg gcgcgatcta ctactcgacg cagttcctgc agttcgtcct
    16501 cggctacgac gccctggaga cgggtgtacg gctgctgccg ctggccggtg cggtgttcgt
    16561 cggcgccatg gtgaccggga agctgacccc gaagctgggg gtgaaggcga tggtcgtgac
    16621 cggcatgctc gtcggtacgg cgggcgtgtt cctgctcacc cagatcgaca agggttcggc
    16681 gtacggggac ttcctggcgc cgatgatgat gctggggttc gcgatcggac tgagcgtctc
    16741 cccggcgacc gacacgatca tggactcctt ccccgagtcc gagctgggtg tcggcggcgg
    16801 tgccaacgac accgcgctgg aactgggcgg ggcactgggc atcgcggtgc tgggctcgct
    16861 gctgggcacg gcctaccggg acgagctgac cgatctggtg ggcaaccggc tcccgggcga
    16921 ggcgatggag gtcgcccagg actcggtcgg cggtggcctg gcggtcgcgg agcgggtcgc
    16981 gcaggatccc tcggccgggc cgcagcaggc gcaggccgtc gtggacgccg tccaccaggc
    17041 cttcgcccac ggggtcgccc agaccagcct catcggcggg atcatcatgg ccgccggcac
    17101 cctgatcgtc ctcgcggtcc tgccgggccg gcgcggcttc gccgagaccg agaagaacgc
    17161 ggagccggtg gccgggacga cggcgaacga gacggcgacg gcggacgagg cggcggtgga
    17221 cgaggcgacg gcggacgagg cggcggcgga gcgggagcgg gccgggtcca tccgctag
//
