LOCUS       reptomyces_RBGC_483862 15961 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_483862
VERSION     Streptomyces_RBGC_483862
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001746295.1
  ORGANISM  GCF_001746295.1
            .
FEATURES             Location/Qualifiers
     CDS             2..408
                     /protein_domains="PF00903"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443440"
                     /pseudo=False
                     /translation="MSEVPAAVRELRLVVTAEDYDEALRFYRDVLGLPERAAFSSPDGR
                     VTILEAGRATLELTDPNHAAFIDEVEVGRRVAGHVRVAFEVDDSALTTARLAEAGAAVV
                     AEPTRTPWNSLNSRLEAPGSLQLTLFTELGE*"
     CDS             complement(498..1165)
                     /protein_domains="PF00072"
                     /protein_domains="PF00196"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443441"
                     /pseudo=False
                     /translation="VSIRVVVADDQELVRSGFTMILEAQQDIEVVAEAGDGAEAVDAVR
                     RHTPDVLLLDIRMPVMDGLEAARCVCAQSSCKVVMLTTFDLDEYVYDALYAGASGFLLK
                     DVRRDDLVHAVRVVAGGDSLLAPAVTRRLVADIVRRRREEAATGATPDRLDVLTAREVE
                     TLRMLARGLSNAEIATTLFVSEHTVKTHVSNVLSKLGLRDRVQAVICAYETGLVAPGAP
                     *"
     CDS             complement(1163..2358)
                     /protein_domains="PF07730"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443442"
                     /pseudo=False
                     /translation="MSAARSWYAPVVTRLRTTNPYVVDSALAVLVLFAASLQWMFPDEG
                     DDRLSLVGWLLGAATAVPLVWRRRSPYACALAVSAATTAMAYYHAPPPDVLYGGFVVLY
                     TMAALGLPWQRRTMLASWLLGAVLTMRHKEHSEPFEYAFHLTGMICAYGLGVLARVQHA
                     YTAAVEDRAGRLERERAAETARAIAQERSRIARDMHDILAHAVSLMVVQAEAGPVVVRS
                     DPDRAEAAFDAIAASGRDAMSQLRRILGVLKEDERRGGAVRLPQPDLAGLPGLIRQVSD
                     STDLQVELSVRGRPRPLPQDTEVAAYRAVQEALTNTVKHAYASSAQVELDWAEDELTLT
                     VTDDGRGPARSDGGHGLIGLRERATACGGSAETGRGPEGGFRVVVRLPAGADREAALG*
                     "
     CDS             complement(2424..3208)
                     /protein_domains="PF01614"
                     /protein_domains="PF09339"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443443"
                     /pseudo=False
                     /translation="MTTRSAPDRLLSVLAAFDHGHPALSLTDISRRAGLTLTTTHRLVA
                     ALTDWGALERDDAGVYHVGLRLWEVAALAPRGVALRQLALPYLEDLYEATHENVQLAVR
                     DGSDVVYIEWIAGRSSVGVHIRVGARWPLHATGVGLVLLAHCEPREQEEYCATPLAVFT
                     PYTITEPARLRRVLAEVRRTGVAVSSRQVTDDALSVAAPVCGPDGTVVAAVSVVVPQDD
                     ARVPALVPAVRLAALGISRALGWQPTVPPRSGAGYPSHR*"
     CDS             complement(3206..3624)
                     /protein_domains="PF12802"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443444"
                     /pseudo=False
                     /translation="MRGLHADTGYLLYRLGLRSGQLFNTFLQESGLRLRHYAVLRYLAG
                     SAGALQRELSTRLGYDPSAIVGLVDDLEKLGLTERRPSPDDRRSKTVVLTEDGRAFLRG
                     TDEAGRRVTNDLLAPLDPAERETLQALLLRVADQP*"
     CDS             3662..3810
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MLACDGGLLGLGVSGRFQHDAPEGLQQLLTSPIIALSFDLVAAPP
                     CIRS"
     CDS             3824..4740
                     /protein_domains="PF13561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443445"
                     /pseudo=False
                     /translation="VPSIDLSGKVAVVTGSGRGLGLAYAHALAAHGASVVVNDVDEAVA
                     DQAVKSIAEAGGTAVAEVVPVGTTEAAERLVNRAVEEFGRLDILVTNAGILRDKVLWKM
                     TDDDFDAVITTHLKGTFTCARAAAVRMREQGEGGSLILVGSPAGQRGNFGQTNYSAAKA
                     GIAAFARTWSMELGRAGITVNAIVPVAATAMTETIPAFAPYIEAMRNGEPLPDFLRKGE
                     GFGTPEDCAALVPFLASEAARGITGQAIGIGGDKVALWSHPQEIRAAYADGGWTPDTLA
                     DAFPTSVGAELQTVGIPAPKLPEA*"
     CDS             4741..5627
                     /protein_domains="PF04909"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443446"
                     /pseudo=False
                     /translation="MDLSMNVDDLVAIDVHTHAEVSSKGHSSLDDDLHDASSAYFKVEG
                     KRKPTLEETAAYYRERKMAAVIFTVDAESATGTAPVPNEEVAEAAAANADVLIPFASID
                     PFRGKAGVKQARRLVEEYGVKGFKFHPSIQGFFPNDRSVAYALYEVIEETGTIALFHTG
                     QTGIGAGVPGGGGIRLKYSNPLHVDDVAADFPHLKIILAHPSFPWQDEALAVATHKPGV
                     HIDLSGWSPKYFPPQLVQYANTLLKDKVLFGSDFPVLTPDRWLADFAKLSIKDEVKPRI
                     LKENAARLLGLTKP*"
     CDS             5640..7144
                     /protein_domains="PF00501"
                     /protein_domains="PF13193"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443447"
                     /pseudo=False
                     /translation="MRNEGLGSWPARRARKTPHRTALIHGDTTFTYAALHTRVTRLAHA
                     LRARGIRRGDRVAYLGPNHPSYLETLFAAGSLGAVFVPLNTRLAGPEIGYQLSDSGARA
                     LVYGPSHAGLVAGLPGSTDVRTYVEVGAEYERLLAESAQEPIDEPVTADDTCIIMYTSG
                     TTGRPKGAMLTHGNLTWNAINVLVDTDLIADERALVSAPLFHTAGLNMLTLPVLLKGGT
                     CVLVEAFEPNATFDLIEQHRITFMFGVPTMFEQVARHPRWADADLSSLRILTCGGSPVS
                     SPLIAAYQERGLTFLQGYGMTEASPGTLFLDAEHAIGKAGSAGVPHFFSDVRVVRPDLA
                     PVDVGETGEVVLRGPHVMPGYWGLPEETAASFADGWFRSGDAARVDEDGYVFIVDRIKD
                     MIISGGENIYPAEIEDLLLGHPDIAECAVIGVPDDKWGEVPRAVVVPREGSAPDPDEVL
                     ASLAGRLAKYKIPKSVVIADGLPRTASGKLLKSRVRKRFGSNS*"
     CDS             7160..7614
                     /protein_domains="PF01575"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443448"
                     /pseudo=False
                     /translation="MSVTVNGLDELKKLAGSDLGTSEWIEVTQERVNTFADATGDHQWI
                     HVDPEKAAAGPFGAPIAHGYLTLSLFIPLFTELLDVQGVTTKVNYGLNKVRFPSPVKVG
                     ARIRLVAKLTDVEEVPGGVQVTVDGAIEIEGGAKPAAVLQSLSRFYA*"
     CDS             complement(7689..9361)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443449"
                     /pseudo=False
                     /translation="MNEQRLPSWADPTVKPADLDAQGVSRRGLLRRAGLFGAAFALGSA
                     ATPAFASSEKRGFGGDDPRLAYLVGDHHVHSVYSHDAKYTFSQQAQAAARYGLDWMVFN
                     EHSNFGHAYYGAELEHAEIVKARAENPRQLIFQGLEWYIPAAEHCTVFAAPGPHETDLL
                     TQFELAYDGKLLGYTEGSAGAADTARNEAHAVKAIKWLAEQRRSGYVDDVLVLANHPLR
                     LGIDSPHEMRGWRDAAPEIMIGMEGAPGAQGAALPGWRGATSIRGEYENKPSAQSWSGY
                     PTDAYLTYGGFDWATATVGGLWDSMLAEGSLFSITTNSDNHRTVFDTWKNGDWPAGQNF
                     DNTGRLPDPVNTDTPQPGSDFWPGEFSRTHVGVTRYGYRAVMAGLRAGRVWVDHGHLLD
                     GLDVRVKRDCDPGRGVTLGGRLRVRKGERITLYVTVTSASRANPQGILPELAHVDVIRG
                     AVRGPVSDRDGWKAPDTRVVQTKDVSGRKGTYTLRIPLTAGDESFYVRLRGSDGKRHGA
                     GYLGASVDPHGPIPHEPGNGDPWADTWFYSNPVFVDVAGS*"
     CDS             complement(9374..11196)
                     /protein_domains="PF13385"
                     /protein_domains="PF00149"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443450"
                     /pseudo=False
                     /translation="VCTSHEHDQGEAAQAGAGRRSFLRATALLGAAATAGVALPTVAEA
                     AVSGYRPDTRSRRFTLAVMPDTQYLFDGPSIDKAPVEAALRYLLEHGKDENIVFLSHLG
                     DLTQNGAAPEFAAIGEAFELLDRRGVGYSVLAGNHDVKSSTTDQRGATPYLDVFGPDRF
                     KGHRTFGGASADGYNTYHVFEAAGREWMVLALDWRLSDQGYAWAKSVLAAHPRTPVVLT
                     THELVVEDDTLSDYGQQLWDRLVKDHDQIFLTLNGHYWPAGRATLKNTVGNDVHLHLTN
                     YQNRYFGGAAMIRLYRFDLDRDVIDVETVSPWILGRASKGLNELERQEIELSGEADRFS
                     VDIDFASRFAGFDPQPARAARPASKMLIRDTAAYWRFDSPVSGTVRDLSGHGNDLTVVS
                     VGGGSLGWSADHHPDQPGHGSLEFQGYKSPLKGAYLRTVDGAPLNSATFKDGYTIEAFY
                     WVPADWDASHNAWSGLVSRTGRNGSVGTVTDDPDEPLATLSLSDGPGPQWAVHPLNQQQ
                     LATNWGDETARETWWHVAVVNDGRHTILYVQGCPVARNPHAPAVGIASAGLPWLLGGYE
                     YADKIDQILHGRLGDVRIVGRALPVSSFMTH*"
     CDS             complement(11237..14160)
                     /protein_domains="PF02836"
                     /protein_domains="PF02929"
                     /protein_domains="PF02837"
                     /protein_domains="PF16353"
                     /protein_domains="PF00703"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443451"
                     /pseudo=False
                     /translation="MTDDPLNSLRPWEAPEVTSWRRLPMNAVDRRSGELPLDGDWRFQL
                     LPAPDAPVGGSWSSAYVPGAWTVQGTDDLPQYTNVRMPFPEYPPHSPAANPTGLYEREV
                     DVPAEWAGRRIVLQVGAAESVLLVHVDGRPVGVSKDSHLAAEFDLTPHVRAGARSVVRL
                     TVVKWSDASHIEDQDQWWHGGITRSVLLYATDPLHLADVTVRASHSGELRVDCRVRDAA
                     GALPEGWYVSGELEGQLLTQDAEFDRFNAEDERVSDFLGEARLRTVVQGVRTWNAETPE
                     LYSLTVRLHRADGTVADTSRHRTGFRDVEITGRDLLVNGERIFVRGVNRHDFHPLTGRT
                     VSYDDMRADLITLKRFGFNAIRTSHYPGDPALYDLADELGFYVVDEADIESHDHAHEIA
                     DDPRYLNAFVDRVSRMVLRDKNHPSVVIWSLGNESDYGANHDAAAGWVRRHDPTRPIQY
                     EGAAKLDWAATGDATDIACPMYASLEECVEHALSGRQTKPLIWCEYSHAMGNSNGTLAD
                     HWAAIESTPGLQGGFIWEFWDHGILQRVNDGRPVGRGGVGLYDNGVAAPGHRWAYGGDF
                     GELLHDGAFIADGVVFPDRTPKPVMYEHREIAAPVRIECFRHEGIVLGNHQHFRGLAWL
                     TGEWELSLADGRTLTASAELPDLRPGETAAVPLPFELPEEGGEAWLTLRVTTAGDEPWA
                     PRGTVVCVPQVRLREAVPQSQVRVKNRSVKVDDDGLLVHPLLTSAPTLSLWRAPTDNDE
                     LGGMAPRWRDWGLDALVRKVADVRLSPGQVTVHAEYASEAGVVRHLQVLTAVEGGIHVA
                     ESAELPDELVDVARVGSVFETVAGLDLMEWYGQGPWESYPDRAFGAPVGHHSVPVDELF
                     TPYLRPQESGGRHGVRHFTLSAPDATGLEVVLDEPRQVGVSRYRAADLTGATHHDELVP
                     RAGCVVHIDAAHRGLGTASCGPDTTASYLVAPGVHRWSWTLRAL*"
     CDS             complement(14158..14996)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443452"
                     /pseudo=False
                     /translation="MAAIKGSLRRGIALHLPLIIGTVLSAFPFYWAVIMSTHSSTEIFS
                     YPPKLLPGTHFLENVRNLFDAIDFFGSMWNSLLVAVSVTFLVLLFDSLAAFVFAKFEFP
                     GKNVLFGLLMVIFMVPAQLSVIPQFVIMAKIGWIGSMTALIVPAAANAFGIFWMRQYMK
                     SAIHDELLDASKLDGANFLRQYWHVALPVVRPGLAFLGIFTFMGQWNDFAWPLIALTNP
                     DNVTLQVALSQLNGTHGTTDYGIVMTGALLALVPLLIVFAIGAKQIIGDLAKGAVRG*"
     CDS             complement(15012..15961)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_443453"
                     /pseudo=False
                     /translation="MAVLEQTPPAVAQPSPTRPKKGLRKYWHLYAAISPFYLIFLGFGL
                     FPVGFSLYLSFHRWDGLGSMEWAGLSQYQYLLSDGDFWNSIGNTIIIWALATFPMIFLA
                     MVTAVMLNSAVRFKGLYRVAYFLPNVTSVVAIAIVFGSIFSTNAGMVNAVLHAVGIDQV
                     AWLNTPWGIKVTIAALMTWQWTGYNAIIFLAGLQTVPGELYEAARMDGAGPVQTFFRIT
                     LPLLRPTLLFVLVVSTVTGLQSFSEPQVLLQTSSNDSTFAGGPGHSGQTMVLYFFQQTF
                     DNNDFGYGAAVAWGIFLVVVLFSIINWRLVQRRGD*"
ORIGIN
        1 atgtccgagg taccagccgc cgtccgtgaa ctccggctcg tcgtcacggc ggaggactac
       61 gacgaggcac tgcgcttcta ccgggacgtc ctcggactgc ccgaacgggc cgcgttctcg
      121 tcacccgacg ggcgggtcac cattctggag gcggggcggg cgacactgga gctgaccgac
      181 ccgaaccatg cggcgttcat cgacgaggtc gaggtggggc ggcgggtcgc agggcatgtt
      241 cgtgtggcgt tcgaggtgga cgactcggct ctcacgacag ccaggctggc cgaggccggg
      301 gccgcggtgg tcgccgagcc gactcgtacg ccctggaact ctttgaattc caggttggag
      361 gcgcctggtt cgctgcaact gacactgttc accgagctgg gcgagtagga gcgtttgaac
      421 ccgcggctgc gtgggggctg gtcgcgccca cgcggcggag cggcatatcg atacagcccc
      481 gcgccccttg gggcgcctag ggcgcccccg gcgccaccag acccgtctcg tacgcgcaga
      541 tcaccgcctg gacccggtcc cgcaggccca gcttgctcag gacgttgctg acatgggtct
      601 tcaccgtgtg ctcgctgacg aacagcgtcg tcgcgatctc cgcgttggac aggccgcggg
      661 ccagcatccg cagggtctcc acctcgcggg ccgtcaggac gtccaggcgg tcgggggtgg
      721 ccccggtggc ggcctcctcg cggcggcggc gcacgatgtc cgcgaccagg cggcgggtga
      781 cggccggcgc gagcagggag tcgccgcccg cgacgacgcg gaccgcgtgc acgaggtcgt
      841 cccggcgcac gtccttgagg aggaagccgc tggcccccgc gtagagcgcg tcgtacacgt
      901 actcgtcgag gtcgaacgtg gtcagcatga ccaccttgca gctcgactgc gcgcacacgc
      961 accgggccgc ctccaggccg tccatgaccg gcatccggat gtcgaggagc agcacgtcgg
     1021 gggtgtgccg gcgcaccgcg tcgaccgcct cggcgccgtc cccggcctcg gcgaccacct
     1081 cgatgtcctg ctgcgcctcc aggatcatgg tgaagccgct gcggaccagt tcctggtcgt
     1141 cggcgacgac cacccggatg ctcacccgag ggccgcttcc cggtccgcgc cggcgggcag
     1201 tcgtacgacg acccggaagc ccccctccgg gcccctcccg gtctccgcgc tgcccccgca
     1261 ggcggtcgcc cgctccctga gtccgatcag cccgtgcccg ccgtccgagc gggccggacc
     1321 tcggccgtcg tcggtcaccg tgagggtcaa ctcgtcctcc gcccagtcga gttccacctg
     1381 tgcggaggaa gcgtacgcgt gcttcaccgt gttggtcagg gcttcctgca ccgcgcggta
     1441 ggcggcgacc tcggtgtcct gggggagggg gcgcggtcgg ccgcgtacgc tcaactcgac
     1501 ctgcagatcc gtcgagtcgg agacctgccg gatcaggccg ggcagtccgg cgaggtccgg
     1561 ctggggcagc ctgacggcac cgccacggcg ctcgtcctcc ttcaacaccc ctagaatccg
     1621 ccgtagttgg gacatcgcgt cccgtccgct ggccgcgatc gcgtcgaacg ccgcctcggc
     1681 gcggtccgga tcactgcgca ccacgaccgg gcccgcctcc gcctggacga ccatcaggct
     1741 caccgcgtgc gcgaggatgt cgtgcatgtc ccgggcgatc cgggagcgtt cctgggcgat
     1801 ggcccgcgcg gtctccgcgg cccgctcccg ctccagccgg ccggcccggt cctcgacggc
     1861 ggcggtgtac gcgtgctgga cgcgggccag tacgccgagg ccgtaggcgc agatcatgcc
     1921 ggtgaggtgg aaggcgtact cgaagggctc ggagtgctcc ttgtgccgca tggtcagtac
     1981 ggccccgagc agccagctcg ccagcatcgt gcggcgctgc cagggcaggc ccagggcggc
     2041 catcgtgtag aggacgacga agccgccgta gagcacgtcg ggcggcggtg cgtggtagta
     2101 ggccatcgcc gtggtggccg cggacaccgc cagggcgcac gcgtaggggg agcggcgccg
     2161 ccagacgagg gggacggcgg tggcggcccc cagcagccag cccaccaggc tcagacggtc
     2221 gtccccctcg tccgggaaca tccactgcag tgacgcggcg aacaggacca gcacggcgag
     2281 cgcgctgtcg acgacgtacg ggttcgtcgt cctcagacgg gtcacgacgg gggcgtacca
     2341 ggaccgggcg gcggacatga gcggctcctc ggggccgggg ccggggccgt tccagtatca
     2401 cgacgccgac gcggccgggt cctcaccggt gagagggata tccggcaccc gaacggggcg
     2461 ggaccgtggg ctgccagccc agtgcccgcg agatgccgag cgccgcgagc cgtaccgcgg
     2521 ggaccaacgc cggtacccgg gcgtcgtcct ggggcaccac gaccgacacg gccgcgacca
     2581 ccgtcccgtc cggtccgcac acgggggcgg ccaccgagag ggcgtcgtcg gtgacctgac
     2641 ggctgctcac cgcgacgccg gtgcgccgca cttcggccag cacccggcgc agtctcgccg
     2701 gttcggtgat ggtgtacggc gtgaagacgg cgagcggggt cgcgcagtac tcctcctgct
     2761 cgcgcggctc gcagtgtgcc agcagcacca gcccgacccc ggtggcgtgc agcggccagc
     2821 gcgcccccac cctgatgtgc acgccgaccg aggaacgccc cgcgatccac tcgatgtaga
     2881 cgacgtccga gccgtcccgc accgccaact gcacgttctc gtgggtggct tcgtagaggt
     2941 cttccagata cggcagtgcc agttgcctga gcgcgacccc gcgcggcgcg agcgcggcga
     3001 cctcccacag tctgagtccg acgtggtaga cgccggcgtc gtcccgctcc agcgcgcccc
     3061 agtcggtcag cgcggccacc agccggtggg tggtggtcag cgtcagcccc gcgcgccggc
     3121 tgatgtcggt cagggacagc gccggatggc cgtggtcgaa cgcggcgagc acggagagca
     3181 gccggtccgg cgcggaacgc gtggtcatgg ctggtcggcg accctcagca gaagggcctg
     3241 gagcgtctcg cgctcggcgg ggtcgagcgg ggcgagcagg tcgttggtca cccgtcggcc
     3301 ggcctcgtcg gtgccgcgca ggaaggcgcg gccgtcctcg gtgagcacga cggtcttgct
     3361 gcggcggtcg tcgggggagg ggcggcgctc ggtcaggccc agcttctcca ggtcgtcgac
     3421 caggccgacg atcgcgctgg ggtcgtagcc gagccgggtg ctcagctccc gctggagggc
     3481 gcccgcggac ccggcgagat agcgcagcac ggcgtagtgg cgcagccgca gtcccgactc
     3541 ctggaggaac gtgttgaaca actgacccga gcgcaggccc aggcggtaca gcaggtaacc
     3601 ggtgtccgcg tgcagtccgc gcatccacgg ctcctccgag tcgatgggct tcggggtgac
     3661 gtgctggcgt gtgatggcgg gctcctcggg ctcggtgtgt cagggagatt ccagcatgac
     3721 gcacccgaag gtctccaaca actattgacg tcaccaatta ttgctcttag cttcgatctc
     3781 gtagccgcac ccccgtgcat ccgttcgtga agggacccgc tcgtgcccag catcgatctc
     3841 tccggcaagg tcgccgtcgt caccggcagc ggccggggcc tcggcctcgc ctatgcgcac
     3901 gccctcgccg cccacggcgc ctccgtggtc gtcaacgacg tcgacgaggc ggtcgccgac
     3961 caggccgtga agtccatcgc ggaggcgggc ggcaccgccg tcgccgaggt ggtcccggtc
     4021 ggcaccaccg aggccgccga gcggctggtg aaccgggcgg tggaggagtt cggacggctc
     4081 gacatcctgg tcaccaacgc gggcatcctg cgcgacaagg tgctgtggaa gatgaccgac
     4141 gacgacttcg acgcggtgat caccacccac ctcaagggca ccttcacctg cgcccgcgcc
     4201 gccgcggtcc ggatgcgcga gcagggcgag ggcggctccc tgatcctggt cggctccccg
     4261 gccgggcagc gcggcaactt cgggcagacg aactactccg ccgccaaggc cggcatcgcc
     4321 gccttcgccc gcacctggtc catggaactg ggccgcgccg gcatcaccgt caacgcgatc
     4381 gtgccggtcg cggccaccgc gatgaccgag accatccccg ccttcgcccc gtacatcgag
     4441 gccatgagga acggcgagcc gctcccggac ttcctccgca agggcgaggg cttcggcacc
     4501 cccgaggact gcgcggccct cgtccccttc ctcgcctccg aggccgcccg gggcatcacc
     4561 gggcaggcca tcggcatcgg cggcgacaag gtggcactct ggtcccaccc gcaggagatc
     4621 agggcggcct acgccgacgg cggctggacc cccgacaccc tggccgacgc cttcccgacg
     4681 tcggtgggcg ccgaactcca gacggtcggc atcccggcac cgaagcttcc ggaggcgtga
     4741 tggacctctc catgaacgtc gacgacctcg tcgcgatcga cgtccacacc catgcggagg
     4801 tgtcctccaa gggccactcc tccctggacg acgacctgca cgacgcgtcc tcggcctact
     4861 tcaaggtcga gggcaagcgg aagccgaccc tcgaggagac cgccgcctat taccgcgagc
     4921 ggaagatggc cgccgtgatc ttcacggtgg acgcggagtc cgcgaccggc accgcgccgg
     4981 tcccgaacga ggaggtcgcc gaggcggccg ccgccaacgc ggacgtcctc atccccttcg
     5041 cgtccatcga cccgttccgg ggtaaggcgg gcgtgaagca ggcccgccgt ctggtcgagg
     5101 agtacggggt gaagggcttc aagttccacc ccagcatcca gggcttcttc cccaacgacc
     5161 ggtcggtggc ctatgccctc tacgaggtca tcgaggagac cggcaccatc gccctcttcc
     5221 acaccggcca gaccgggatc ggggcgggcg tccccggcgg gggcggcatc cgcctgaagt
     5281 actccaaccc gctccacgtg gacgacgtgg cggccgattt cccgcatctg aagatcatcc
     5341 tggcgcaccc gtccttcccc tggcaggacg aggccctcgc cgtcgccacc cacaagccgg
     5401 gcgtgcacat cgacctgtcc ggctggtcgc cgaagtactt cccgccgcag ctcgtgcagt
     5461 acgcgaacac cctgctcaag gacaaggtcc tcttcggctc cgacttcccc gtcctcaccc
     5521 ccgaccgctg gctcgccgac ttcgcgaagc tgtcgatcaa ggacgaggtg aagccgagga
     5581 tcctcaagga gaacgccgcc cgtctgctcg ggctcaccaa gccataaagg ggcctcagat
     5641 gcgcaacgag ggactgggct catggcccgc acgccgggcc cgcaagaccc cgcaccgcac
     5701 cgccctgatc cacggcgaca ccacgttcac gtacgccgca ctgcacaccc gcgtcacgcg
     5761 cctcgcgcac gccctgcgcg cccggggcat ccggcgcggc gaccgcgtcg cctacctcgg
     5821 cccgaaccac ccctcctacc tggagacact gttcgcggcc ggctccctgg gcgcggtctt
     5881 cgtccccctc aacacccgcc tcgccggacc ggagatcggc taccagctct ccgactccgg
     5941 ggccagggca ctggtctacg gcccctcgca cgcggggctc gtcgccggac tgccgggcag
     6001 caccgacgtc cgtacctacg tcgaagtcgg cgccgaatac gagcggttgc tcgccgagtc
     6061 ggcgcaggaa ccgatcgacg agccggtcac cgccgacgac acctgcatca tcatgtacac
     6121 ctcgggcacg accggccgcc ccaagggcgc catgctcacc catggcaacc tgacctggaa
     6181 cgcgatcaac gtcctcgtcg acaccgacct gatcgccgac gaacgcgccc tggtctccgc
     6241 accgttgttc cacacggccg gcctgaacat gctgacgctg cccgtgctgc tgaagggcgg
     6301 cacctgcgtc ctggtcgagg ccttcgagcc gaacgcgacc ttcgacctga tcgaacagca
     6361 ccggatcacc ttcatgttcg gggtcccgac gatgttcgag caggtggcga ggcacccgcg
     6421 ctgggcggac gcggacctgt cctccctgcg gatcctgacc tgcggcggct ccccggtgtc
     6481 gagccccctg atcgccgcgt accaggagcg cgggctcacc ttcctccagg gctacggcat
     6541 gaccgaggcc tcgcccggca ccctgttcct ggacgccgag cacgccatcg gcaaggcggg
     6601 ttcggcgggc gtgccgcact tcttcagcga tgtccgggtg gtacggccgg acctggcgcc
     6661 cgtcgacgtc ggcgagaccg gcgaggtcgt gctccggggg ccgcacgtca tgcccggcta
     6721 ctgggggctg cccgaggaga ccgccgcctc cttcgcggac ggctggttcc gcagcgggga
     6781 cgcggcccgc gtcgacgagg acggctacgt cttcatcgtc gaccgcatca aggacatgat
     6841 catctccggc ggcgagaaca tctaccccgc cgagatcgag gacctgctcc tcggccatcc
     6901 ggacatcgcc gagtgcgcgg tcatcggtgt cccggacgac aagtggggcg aggtgccgcg
     6961 ggcggtcgtc gtgccgcgcg agggcagcgc gcccgacccg gacgaggtcc tggcctccct
     7021 ggccggacgg ctcgccaagt acaagatccc caagtcggtg gtgatcgcgg acggactccc
     7081 gcgcaccgcc tccggaaagc tcctcaagtc ccgggtgcgc aagcgcttcg gctccaactc
     7141 ttaggtaagg acagctacat gagcgtcacc gtcaacggcc tcgacgaact gaagaagctc
     7201 gccggcagcg acctcggcac cagtgagtgg atcgaggtca cccaggagcg cgtcaacacg
     7261 ttcgccgacg ccacgggcga ccaccagtgg atccacgtgg accccgagaa ggcggcggcg
     7321 ggccccttcg gcgcaccgat cgcgcacggc tacctcaccc tctcgctgtt catcccgctc
     7381 ttcaccgagc tgctggacgt ccagggcgtc accaccaagg tcaactacgg cctgaacaag
     7441 gtccgtttcc cctcgccggt gaaggtgggc gcgcgcatcc gcctcgtcgc caagctcacg
     7501 gacgtcgagg aggtgcccgg cggtgtgcag gtcaccgtcg acggggcgat cgagatcgag
     7561 ggcggggcca agccggccgc ggtgctgcag agtctgtcgc ggttctacgc ctgacggcag
     7621 gagtacacgg ccgtcgacag agcgcacacc ccgggcggga tcgtctccgc ccggagtgtg
     7681 cccgtgatca gctacccgcc acgtccacga agacggggtt ggagtagaac cacgtgtccg
     7741 cccacgggtc accgttcccg ggctcgtgcg gaatcggacc gtgcgggtcg accgaggcgc
     7801 cgagataccc cgcaccgtgc cgcttgccgt cgctgccgcg cagccggacg tagaaggact
     7861 cgtccccggc ggtcagcggg atgcgcaggg tgtacgtccc cttccggccg gacacgtcct
     7921 tcgtctgtac gaccctggtg tcgggagcct tccagccgtc ccggtcgctc accggacccc
     7981 gtaccgcgcc ccggatcacg tccacgtgcg ccagctccgg caggatcccc tgcgggttgg
     8041 cccgggaggc gctggtgacg gtgacgtaca gcgtgatcct ctcgcccttg cggacccgca
     8101 gccgcccgcc cagcgtgacc ccgcgtcccg ggtcgcagtc ccgcttcacc cggacgtcga
     8161 gcccgtcgag cagatgcccg tggtccaccc agacccggcc cgcgcgcagg cccgccatca
     8221 ccgcgcggta gccgtagcgg gtcacgccga cgtgggtgcg gctgaactcg cccggccaga
     8281 agtcgctgcc gggctgcggg gtgtcggtgt tcaccgggtc gggcagcctg ccggtgttgt
     8341 cgaagttctg gccggccggc cagtcgccgt tcttccatgt gtcgaagacc gtgcggtggt
     8401 tgtcggagtt cgtggtgatc gagaacaggc tgccttccgc cagcatcgag tcccacagcc
     8461 cgccgacggt cgccgtcgcc cagtcgaagc cgccgtacgt cagatacgcg tccgtcggat
     8521 agcccgacca cgactgcgcc gacggcttgt tctcgtactc gccgcggatc gaggtggccc
     8581 cgcgccagcc ggggagcgcc gcgccctggg cgcccggtgc gccctccatg ccgatcatga
     8641 tctcgggggc cgcgtcccgc cagccccgca tctcgtgcgg ggagtcgatg ccgagccgca
     8701 gcgggtggtt ggcgagcacg aggacgtcgt cgacgtagcc cgaacggcgc tgctccgcca
     8761 gccacttgat cgccttgacg gcgtgggcct cgttgcgcgc ggtgtcggcg gcgcccgcgg
     8821 atccctccgt gtagcccagg agcttgccgt cgtaggcgag ctcgaactgt gtgagcaggt
     8881 cggtctcgtg cgggccgggg gccgcgaaca ccgtgcagtg ctcggcggcc gggatgtacc
     8941 actccaggcc ctgaaagatc agctggcgcg ggttctccgc acgggccttg acgatctccg
     9001 cgtgctccag ctcggcgccg tagtaggcgt gtccgaagtt ggagtgctcg ttgaacacca
     9061 tccagtcgag gccgtaccgg gcggcggcct gcgcctgctg ggagaacgtg tacttcgcgt
     9121 cgtggctgta cacggagtgg acgtggtggt cgcccaccag ataggcgagg cgcgggtcgt
     9181 cgcccccgaa accccgcttc tcggaggagg cgaaggcggg ggtcgccgcc gagccgaggg
     9241 cgaacgcggc gccgaacagg ccggcgcggc gcaggagccc gcgtctcgac acgccttgtg
     9301 cgtcgaggtc ggcgggtttg acggtggggt cggcccagga gggcagtcgc tgctcgttca
     9361 tggtgattcc cgtcagtgag tcatgaagga ggagacgggc agggcgcgtc cgacgatccg
     9421 gacgtcaccg aggcggccgt gcaggatctg gtcgatcttg tcggcgtact cgtagccgcc
     9481 gagcagccag ggcagcccgg ccgaggcgat gccgacggcg ggggcgtgcg ggttgcgggc
     9541 gacggggcag ccctggacgt acagaatcgt gtgccgcccg tcgttgacca cggccacgtg
     9601 ccaccacgtc tcgcgggcgg tctcgtcacc ccagttggtg gcgagctgct gctggttgag
     9661 cggatgcacc gcccactgcg ggcccggtcc gtcggagagg gacagcgtgg ccagcggttc
     9721 gtccgggtcg tcggtgaccg tgccgacgga gccgttgcgg ccggtgcggc tgacgaggcc
     9781 ggaccaggcg ttgtgcgagg cgtcccagtc cgcggggacc cagtagaacg cctcgatggt
     9841 gtaaccgtcc ttgaacgtgg ccgagttgag cggagccccg tcgacggtcc gcagatacgc
     9901 gcccttcagc ggtgacttgt agccctggaa ctccaggctg ccgtggcccg gctggtcggg
     9961 gtggtggtcg gccgaccagc cgagggagcc gccgcccacc gagaccacgg tgaggtcgtt
    10021 gccgtgcccg gacaggtcac ggacggtgcc ggagacgggc gagtcgaagc gccagtaggc
    10081 ggccgtgtcc cggatcagca tcttcgacgc gggccgcgcc gcacgcgcgg gctgcggatc
    10141 gaagccggcg aaccgcgagg cgaagtcgat gtcgacggag aaccggtcgg cttcgccgct
    10201 gagttcgatc tcctgccgtt ccagctcgtt gagccccttc gaggcccgac ccaggatcca
    10261 cggggagacc gtctccacgt cgatcacgtc acggtcgagg tcgaagcggt acaggcggat
    10321 catggcggcg ccgccgaagt accggttctg gtagttcgtc agatgcaggt ggacgtcgtt
    10381 gcccacggtg ttcttgaggg tcgcccgccc ggccggccag tagtgcccgt tgagggtcag
    10441 gaagatctgg tcgtggtcct tgaccagccg gtcccacagc tgctgaccgt agtccgagag
    10501 ggtgtcgtcc tcgacgacca gctcgtgcgt ggtcaggacg accggcgtcc tcgggtgggc
    10561 ggccaggacg ctcttcgccc aggcgtaccc ctggtccgac agacgccagt ccagggcgag
    10621 gaccatccac tcgcggcccg cggcctcgaa gacgtggtac gtgttgtagc cgtcggcgga
    10681 ggcacccccg aaggttctgt gacccttgaa ccggtcgggc ccgaagacgt ccaggtacgg
    10741 cgtcgcaccg cgctggtcgg tggtggagga cttcacgtcg tggttgcccg cgaggacgct
    10801 gtagccgaca ccccggcggt cgagcagctc gaacgcctcg ccgatcgcgg cgaactcggg
    10861 tgccgcgccg ttctgcgtga ggtcgccgag gtgggacagg aagacgatgt tctcgtcctt
    10921 cccgtgctcc agcagatacc gcagtgcggc ctcgacggga gccttgtcga tgctcggccc
    10981 gtcgaagagg tactgcgtgt cgggcatgac ggcgagcgtg aaccgccggc tgcgggtgtc
    11041 gggacgatac ccggacaccg cggcctcggc cacggtcggc agggcgacgc ccgccgtggc
    11101 ggccgcgccc agcagtgccg tcgcccgcag gaaactgcgc cgtccggcac cggcctgggc
    11161 ggcctcgccc tgatcgtgct catgcgaagt gcacacgtgt gctccattgc aggggaagtg
    11221 aagaagaagg gggagtcaga gggcgcgcag agtccagctc cagcgatgga cgcccggcgc
    11281 gacgagatag gaggcggtgg tgtccggtcc gcaggaggcg gtgccgaggc cgcggtgggc
    11341 cgcgtcgatg tgcacgacac agcccgcccg cgggacgagt tcgtcgtggt gggtggcgcc
    11401 ggtgaggtcc gcggcgcggt accggctcac accgacctgg cgcggttcgt ccaggacgac
    11461 ctcgaggccg gtggcgtccg gcgcggagag cgtgaagtgc cgtacgccgt gccggccgcc
    11521 gctctcctgc gggcgcagat agggggtgaa cagttcgtcc acgggcaccg agtgatggcc
    11581 gacgggcgct ccgaaggcgc ggtccgggta cgactcccag ggtccctgtc cgtaccactc
    11641 catcaggtcg agcccggcga ccgtctcgaa gacggagccg acccgcgcca cgtcgacgag
    11701 ttcgtccggc agctcggccg actccgcgac gtggattccg ccctcgaccg cggtgaggac
    11761 ctgcagatgg cggacgacac cggcctcgga ggcgtactcg gcgtgaacgg tgacctgtcc
    11821 ggggctcagg cgtacgtcgg cgaccttgcg caccagggcg tcgagccccc agtcacgcca
    11881 gcgcggtgcc atgccgccga gctcgtcgtt gtcggtgggc gcccgccaca gggagagcgt
    11941 gggtgcggag gtgagcaggg ggtggaccag gagaccgtcg tcgtccacct tgacggaacg
    12001 gttcttcacc ctcacctggg actgcggaac cgcctcacgc agccgcacct gcggcacgca
    12061 caccaccgtc ccgcgcggcg cccagggctc gtccccggcg gtcgtcaccc tgagtgtcag
    12121 ccatgcctcg ccgccctcct cgggcagctc gaacggcagt ggtaccgctg ccgtctcgcc
    12181 gggccgcaga tcgggcagtt cggcggacgc ggtcagggtg cgtccgtcgg cgagcgagag
    12241 ctcccactcg ccggtcagcc aggccaggcc ccggaagtgc tggtggttgc cgagcacgat
    12301 gccctcgtgc cggaagcact cgatgcgcac cggcgccgcg atctcccggt gctcgtacat
    12361 caccggcttg ggcgtgcggt cggggaagac cacaccgtcc gcgatgaagg cgccgtcgtg
    12421 gaggagttcg ccgaagtcgc cgccgtacgc ccagcggtgg ccgggtgcgg cgacaccgtt
    12481 gtcatagagc ccgacgcccc cacgtccgac cggtctgccg tcgttcacac gttgcagaat
    12541 gccgtggtcc cagaactccc agatgaaccc gccctgaaga cctggcgttg actcgatggc
    12601 ggcccaatgg tccgcgagcg tgccgttgct gttgcccatg gcatgggagt actcgcacca
    12661 gatcaggggc ttggtctggc gcccggagag cgcgtgctcc acacactcct ccagcgaggc
    12721 gtacatcggg caggcgatgt cggtcgcgtc accggtcgcc gcccagtcga gcttggccgc
    12781 cccctcgtac tggatcggcc gcgtcggatc gtgccggcgc acccacccgg cggccgcgtc
    12841 gtggttcgcc ccgtagtccg actcgttgcc cagcgaccag atgacgaccg acggatggtt
    12901 cttgtcccgc agcaccatcc gcgagacccg gtccacgaag gcgttcagat agcgcgggtc
    12961 gtcggcgatc tcgtgggcgt ggtcgtggga ttcgatgtcc gcctcgtcga cgacgtagaa
    13021 accgagttcg tccgcgaggt cgtagagggc gggatcgccc gggtagtggg aggtgcggat
    13081 cgcgttgaac ccgaagcgct tgagcgtgat caggtccgcg cgcatgtcgt cgtacgacac
    13141 cgtccgcccg gtcagcgggt ggaagtcgtg ccggttcacg ccccggacga agatccgctc
    13201 gccgttgacc agcaggtccc ggccggtgat ctcgacgtcc cggaagccgg tccggtgccg
    13261 tgaggtgtcg gcgaccgtgc cgtcggcgcg gtgcagccgt acggtgagcg agtacagctc
    13321 gggggtctcg gcgttccagg tgcggacgcc ctgcacgacg gtccgcagcc gggcctcgcc
    13381 gaggaagtcg gagacccgct cgtcctcggc gttgaaccgg tcgaactccg cgtcctgggt
    13441 gagcagttgc ccctccagct cgccgctgac gtaccacccc tcgggcagtg cgccggccgc
    13501 gtcccgcacc cggcagtcca cccgcagctc gccgctgtgg gacgcccgca cggtcacgtc
    13561 cgccagatgc agcggatccg tcgcgtacag cagcacggac cgcgtgatcc cgccgtgcca
    13621 ccactggtcc tggtcctcga tgtgcgaggc gtccgaccac ttgaccaccg tcagccgtac
    13681 gacgctccgc gcgccggcgc gcacatgtgg cgtcagatcg aactcggccg ccagatggga
    13741 gtccttggag acgccgacgg gccgcccgtc cacgtgcacg aggagcacgc tctcggcggc
    13801 cccgacctgg agcacgatcc ggcgtccggc ccactcggcg ggcacgtcca cctcgcgctc
    13861 gtacaagccc gtggggttgg ccgcggggga gtggggcggg tactcgggga acggcatccg
    13921 cacgttcgtg tactgcggca ggtcgtcggt gccctgcacg gtccaggccc ccggcacgta
    13981 ggccgaggac caggagccgc cgaccggcgc gtccggagcg ggcagcaact ggaagcgcca
    14041 gtcgccgtcc agggggagtt ctccggagcg ccggtcgacg gcgttcatgg gcagcctccg
    14101 ccaggaggtc acctcaggtg cctcccaggg gcgcaaggag ttcaggggat cgtccgtcat
    14161 ccgcgcacgg cccccttggc gaggtcaccg atgatctgct tggcgccgat ggcgaacacg
    14221 atcagcagcg ggacgagggc gagcagggca ccggtcatca cgatgccgta gtcggtcgtg
    14281 ccgtgggtgc cgttgagctg ggacagcgcg acctggaggg tcacgttgtc ggggttggtg
    14341 agggcgatca ggggccaggc gaagtcgttc cactggccca tgaaggtgaa gatgccgagg
    14401 aaggccagac cggggcggac caccggcagc gccacgtgcc agtactggcg gaggaagttc
    14461 gcgccgtcca gcttggaggc gtcgagcagc tcgtcgtgga tggcggactt catgtactgg
    14521 cgcatccaga agatgccgaa ggcgttggcc gcggccggca cgatcagcgc ggtcatcgag
    14581 ccgatccagc cgatcttcgc catgatcacg aactgcggga tgaccgagag ctgcgccggc
    14641 accatgaaga tgaccatgag cagtccgaac agcacgttct tgcccgggaa ctcgaacttg
    14701 gcgaagacga aggccgcgag cgagtcgaag agcaggacga ggaaggtcac cgacaccgcg
    14761 accagcagcg agttccacat cgatccgaag aagtcgatgg cgtcgaagag gttgcggacg
    14821 ttctccagga agtgcgtgcc cggcagcagc ttcggcgggt aggagaagat ctccgtcgag
    14881 ctgtgcgtcg acatgatcac ggcccagtag aacgggaagg ccgagagcac ggtgccgatg
    14941 atcagcggga ggtgcagcgc gatccctctg cggagggatc ccttgatggc agccatgatg
    15001 cgcgcccttc ctagtcgccg cggcgctgca cgaggcgcca gttgatgatc gagaagagga
    15061 cgacgacgag gaagatgccc cacgccaccg cggcgccgta cccgaagtcg ttgttgtcga
    15121 aggtctgctg gaagaagtag aggaccatcg tctggcccga gtggcccgga ccgcccgcga
    15181 acgtcgagtc gttggacgag gtctggagca ggacctgtgg ttcggagaag ctctgcagac
    15241 cggtgaccgt cgagacgacg agcacgaaca gcagcgtggg ccgcagcagg ggcagcgtga
    15301 tgcggaagaa cgtctggacc gggccggcgc cgtccatgcg cgccgcctcg tacagctcgc
    15361 ccgggacggt ctggagcccg gcgaggaaga tgatggcgtt gtagccggtc cactgccagg
    15421 tcatcagggc ggcgatggtg accttgatgc cccatggcgt gttcagccac gcgacctggt
    15481 cgatcccgac cgcgtgcagg acggcgttca ccatgccggc gttggtggag aagatcgagc
    15541 cgaagacgat ggcgatcgcg acgacggagg tgacgttcgg caggaagtac gcgacgcggt
    15601 acaggccctt gaaccggacc gccgagttga gcatcacggc cgtgaccatc gccaggaaga
    15661 tcatggggaa ggtggccagc gcccagatga tgatcgtgtt gccgatcgag ttccagaagt
    15721 cgccgtcgct cagcaggtac tggtactgcg agagcccggc ccactccatc gagccgaggc
    15781 cgtcccagcg gtggaaggac aggtagagcg agaagccgac cgggaacagg ccgaagccga
    15841 ggaagatcag atagaagggg gagatggcgg cgtagaggtg ccagtatttg cgcaggccct
    15901 tcttgggccg cgtgggcgag ggctgggcca cagcgggcgg agtctgctcg aggacggcca
    15961 t
//
