LOCUS       reptomyces_RBGC_518976 16442 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_518976
VERSION     Streptomyces_RBGC_518976
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000717725.1
  ORGANISM  GCF_000717725.1
            .
FEATURES             Location/Qualifiers
     CDS             2..690
                     /protein_domains="PF00072"
                     /protein_domains="PF00196"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969134"
                     /pseudo=False
                     /translation="MEALPLRVVVADDQALVRTGFRLILESEGIEVVAEAEDGEQAVSA
                     VRRCRPDVVLMDIRMPGLDGLEATRRILADPGEEPPRIIMLTTFDLDHYVYAAVAAGAS
                     GFLLKDVTPEHLAAAVRLVRTGDALLAPAITRRLVERFARPQARETATPHRELGTLTPR
                     ELEVMALLARGLSNAELAARLQLSEATVKTHVARILGKLGLRDRAQVVVAAYETGLVSV
                     GAAPEAP*"
     CDS             complement(786..3001)
                     /protein_domains="PF00141"
                     /protein_domains="PF00141"
                     /protein_domains="TIGR00198"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969135"
                     /pseudo=False
                     /translation="MSDIHDATGVEAKAEGCPVNHGRAPHPTQGGGNRQWWPERLNLKI
                     LAKNPAVANPLGADFDYAAAFNALDLPAVKRDIQEVLTSSQDWWPADYGNYGPFMIRMA
                     WHSAGTYRISDGRGGAGGGQQRFAPLNSWPDNASLDKARRLLWPVKKKYGRSLSWADLI
                     ILTGNVALEGMGFRTFGFGGGRVDEWEPDEDVYWGPETTWLGDERYTGDRELENPLAAV
                     QMGLIYVNPEGPNGNPDPIAAARDIRETFYRMAMNDEETVALIAGGHTFGKTHGAGPAD
                     NVGADPEAAPIEQQGLGWKSTLGTGVGADAITSGLEGAWTPTPITWDNSFFETLFGYEW
                     ELTKSPAGAHQWKPKDGAGEGTVPDAHDPSKRHVPIMLTTDLSLRLDPVYEPISRRFLE
                     NPDQFADAFARAWYKLTHRDMGPVVRYLGPEVPGEHLLWQDPLPQASYRQVEAADVADL
                     KRRINATGLSVTELVSTAWAAASSFRSSDKRGGANGARIRLQPQIGWEVNEPDRLASVL
                     RTLEGVRNDFNAQADGKQVSLADLVVLAGGVGVEQAAKAAGLAVEVPFAPGRVDASQEQ
                     TDTESFAALEPKADGFRNWVGKGNRLPAEYLLLDKANLLGLSAPELTVLVGGLRVLGAN
                     HGGSAHGVLTSTPGVLTNDFFVNLLDLDTRWAPTSEDSHTFEARDASGKVTWTGTRADL
                     VFGSNAELRAVAEVYASDDAKEKFVTDFVAAWTKVMNADRFDLV*"
     CDS             3282..3694
                     /protein_domains="PF01475"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969136"
                     /pseudo=False
                     /translation="MSDLLERLRGRGWRLTSQRRVVAEVLDGEHVHLTADEVHARAAAR
                     LPEISRATVYNTLGELVTLGEVIEVATDGRAKRYDPNAHRPHQHLVCTGCGAIRDVHPL
                     GNPLADLPAEQRFGFTVSQAEVTYRGLCPDCTG*"
     CDS             3850..4328
                     /protein_domains="PF02082"
                     /protein_domains="TIGR00738"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969137"
                     /pseudo=False
                     /translation="MRMGEGVEWGLHCCLTLAWLGDEQPVPTGRLAAWFDLPPAYLTKR
                     LQALVRAGILGSTPGARGGFRLGRPPESITLMDVVAAIEGTDDLFRCTEIRQRTEGAAA
                     AGDDFRRPCGVSTAMRRAELAWRRELAGQTVADLMAAAPAGAAERTRRHYARLTG*"
     CDS             4406..5589
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969138"
                     /pseudo=False
                     /translation="MSDVLISKAPPRTTGGLSATLVLALGTFAVGTDACVVAGFLPSMA
                     EDLHVSPATAGQSVTVFAAAYAVLSPLLATLLARLPRRTLLIAALTALGLANLGSALAP
                     TTAALLATRVLAAAGAAAYTPNAGAVSAALVRPELRARALAVVIGGLTVATAIGVPLGN
                     AAEHWFGWRTALGLVAGLCLVVAAVLRAVMPRLPGNARVPLRTRLAVLRRPAVLTVLPL
                     TVLGMGASYTAYAYSVPVLEAVGVSGGSVLWMLLLYGAGAVVGNLAAGWATDRWGSVTV
                     LTVGYGTMTAALGLLAWLAAAGASAVPPVGLLVLLWGAASWCQTPPQQHRLIGLAPQEA
                     PLLVSLNSSAIYAGIGLGTVLGGATLASGAAVVYGLGAGLAAAALLFLRCSARS*"
     CDS             complement(5656..6563)
                     /protein_domains="PF01061"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969139"
                     /pseudo=False
                     /translation="VTVETTSTTSTTKTPGATETTETTETSDTAATAPATAVPRQAEAG
                     RRTWQHDVLAVLYREYCLLTRNRTNLLLAITPSAVYLLLFATSLSRLIGDVRYQGRPFG
                     YAEFTVPALLLSSMLAAATTAGASLFQERMGNMDVELWSYPLRRGSYITAKLTAGAALV
                     LAQTLAALALAGVLFSFRWPADHWAALLLATVLASVAFNGLYLLLATAFKDFQRFTVTI
                     NVLAPVLLFAAPSFYPVEQMAPLLRWLSWADPVTYGIRCLRDAALFGFGTAWPWMLVLA
                     GIAVATGVLITRSMVRQARRL*"
     CDS             complement(6554..7497)
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969140"
                     /pseudo=False
                     /translation="MTAAVQAENLVKRYEGMQRNAVDGLSFTIEPGSVVGLLGPNGAGK
                     TTLTKLLCGAAVPTAGRITVFGAGPSAHGGRAKLDIGVVHQSAPFDMMLTVLDNLRIAA
                     VLKGVRWRNARPACYELLDALGLKDALSQLVFTLSGGEKRRLQVVRALLGRPRLLLLDE
                     PSAGLDVSGRRRIWELLRELREQDGTTVLWTSHYVEELERNCARVLIVDRGRLLEHGSP
                     ADLAERFGNQTALVRPVDPEDSARLAGLAEQAGLSAVAADGAVRITGRGVRDLLPGVMA
                     RLGSPEGRSAPVEFRTPSLEDAFLELVENRRDR*"
     CDS             complement(7495..8378)
                     /protein_domains="PF00717"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969141"
                     /pseudo=False
                     /translation="VRHTPEGPSEAVVLRAVLAAAGRARLRTRGESMLPAIAPGTVVTV
                     EALPLPRVVPGDVVAAVIGARIIVHRVVATAPDVLLTAGDNLPLLDPVVGPDGYLGVVP
                     EYHAAVPPRQPALSALGPLPRERERDHDHDRGPGRTRLLIPGPVAGHRSTDLDVRQCER
                     PGRLAGPVIGISPFGALPPEALDTVLRAAGGRDLTILVGYSFGYPQAADGGRPLLPPDT
                     ADLHLRFGSPLDPPGLAATLDFAADRVRALRPAPPAAAASPTAAVLAAAAVTAASALAA
                     ATPLTDTDGGCPR*"
     CDS             complement(8363..8652)
                     /protein_domains="PF05402"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969142"
                     /pseudo=False
                     /translation="MRYRIDPEVVWTRSDGEVRLYSARIGEFQTLNSTAAEIWILLSED
                     RSAEDATAELIRRYGATSPAQQALITRDISEFVARLVAEGLVQEESGAAHA*"
     CDS             complement(8668..10088)
                     /protein_domains="PF04055"
                     /protein_domains="PF13186"
                     /protein_domains="TIGR04085"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969143"
                     /pseudo=False
                     /translation="MKLLDLWDDLLVPDDLVYFANDGDRLVTNPELAAWCILSEPETRV
                     LQALARRRPRPAPATEDTDAAERTLAKLVLNWLVYLPGRRPAIREPEPPLTTVYYAITD
                     GCNLRCPYCYASSEKALPGELDTAESLDLVDQIADMKVGHLIFTGGEPMLRKDLFQIAR
                     HARDRGLAVNMITNGTVIRRPETARQIAELFNLVTVSVDGGTAEMHERTRGKGTFARTA
                     NGLRLLNEAGVVPVINHVVTPENVDLLDRLAEFVGGLDIARVRLMNHSDLGRAATDGYD
                     FGWGEYQKILDFMWTNPLTKNLLPEGPKASKPCSIRGNCGMGGNEIYINSLGNVYPCKL
                     VTEKQHLAGNVRRKPLAEIFAAPVLADLRRNSVYAGENLKDCRRCYIRGACGGGCRAYH
                     MAETGDIHRNGRHLCRILRRSMIASIWESTGVPGARLKAEQETMMTPRLVLDDSVHPVH
                     DDWKTAGRRLLPLAN*"
     CDS             complement(10221..10339)
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_969144"
                     /pseudo=False
                     /translation="MHESAWVKPEIAPVDFDAEMGCACACGALAGSGSGQSDS*"
     CDS             10569..11002
                     /protein_domains="PF13560"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969145"
                     /pseudo=False
                     /translation="VAAPEPGAPAPTLAEQIDRLFQTIRRPNHEPYSNEEVARACREAT
                     GESFSATYLWQLRTGRRDNPTKRHLEALAQFFQVPPAYFFDDGLSEQIAEELALLGALR
                     DAGVREVALRAVTLSPEGLGTISDMIEAIARREARSQRSD*"
     CDS             11087..11802
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969146"
                     /pseudo=False
                     /translation="VVVGWQRTVGGRQQRELWRRCRSIAATLPVRETFDPDALAADLSA
                     RLGRPVELLPLAWPPTSGPCGLLVSTDRADYIGYPRDTTPLHQRHIVLHEVGHLLCGHR
                     GGPDVLAGATAETLLPSLSGELIRRVLGRTGYTETEEREAELFASLVLHRAARQGRAPS
                     AAAGAPEVSETAARLGSVFGATATGNPTAAGNPTAAGSPTAAGSPAAAGSSMAAPGAGH
                     RAAPARPAATPGPDPR*"
     CDS             11800..13034
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969147"
                     /pseudo=False
                     /translation="VTELVAYLAGAVALLSAGHRIRLIWGHRADAGARYLIGLGLCVGL
                     SLVLLSRSASQAVRPPLTDLLPLLGGEAKLAAGSFLALMAHSVRPGDRARRWARRQSAL
                     SLTVMVAAAAAYLAAGVRAGDGEFTVSDSGRAALTVYNALFTAHSLVCVGLFTVVVHRS
                     ARHVGPGLLRTGLRVVVAGGVSAFVWSALGLFPLVVAFRTGHRATAEASWSVPFALLSS
                     ALGIGGATLPGWGARLAGPLRRLRAWRSYRRIGPLWSALHAAHPQIALDARTPGGMLSV
                     PLRNAEFALYRRVIEIHDGRLALRAHVHPQVPDWAAAACAGLPAGHPRAAAVEAAVIAA
                     AIEAAAAGLRFRVPAVSPAPHPDPCDLAAEVGWLTEVSDAFARSVAVERIRRRVRTDLC
                     GNPAAGDATPVE*"
     CDS             complement(13040..14358)
                     /protein_domains="PF00067"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969148"
                     /pseudo=False
                     /translation="VTLDQAYVNQIFLPATYADGVPYGLFRELRSAAPVWWVEEPAVGE
                     WPGGPGYWAVLRHAEVKQVLRSPAVFSSHLGATQIRDPDSAADLEFARTMMLNQDPPDH
                     SRLRRIVAGAFTPRALGELAAGIEEQAAAAVRRVRAQGEADFVRIVADLPVRTLAWIMG
                     VPDQDRQLLQDWANRVIGYQDADYADAGTAGTAGTVGLTELGRTALVHRPTARSTADGR
                     PVNPRSRAALADMFAYAHAVAEQPRPGSMVARMREGGLDTAEFETMFFLFAVAGNETVR
                     NALPGGVHALLTHPEQYRLLCERPELGPSAVEEMLRYWPPVVDFRRTAARDVELGGRPI
                     RRGDKVVVYHASANRDETVFPDPDRFDITRSPNDHVSFGFGPHFCVGAQLARLQMTAML
                     RHVLAELPGLALVPGAAPDRLVSNFQNGLKHLPVRWQPRT*"
     CDS             14449..16442
                     /protein_domains="PF13424"
                     /protein_domains="PF13374"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_969149"
                     /pseudo=False
                     /translation="VQGQQGWQVRNGIDNSTVNGNTFQARELTVNLPPAPADAQWPMVI
                     GRIPPRASAFQPRDELRQAIDAAREQHGTVVLSQVLAGGGGVGKSQLAGHYARAAIDAG
                     TGLVLWVDAADPGNVTHVYARAAATVRVPGLGGTAEEDAEKFLTWLASTDRSWLIILDN
                     ATEHTPESLWPATSRGARGRVIATTRHRGAASTGSDRTLVNIGTYSPAESAAYLRERME
                     RAGCSHFLDEHAAELAEALGHLPLALAHAAAYMINTRRSCGRYLGLFRDLTRSLDAVLP
                     ARSSADGYRGPVTAALLLAVDAAQKEHPVGLALPVLQLAALLDPAGHPRQLWTTAPVLD
                     HLSRIRGTSIADDDALDALAVLHNYNLYNLVTLTETPHREVSLHALTARAVLGTPYDRE
                     PYQNAIAEGLIGLWPNEDYSFRDLAAVLRANTDALITQSGDLLWNLSTGAHQLFNRVGH
                     SLLNAGLYTAGIQHWGLVIAVLERTYGADDLNTLTCRSNLATSYRRAGRTDDAVALQER
                     VLADHERIFGSDHPETLICRNNLATSYQQAGRTDDAIRLQERVLADHEHSLGSDHPDIL
                     TCRNNLAMSHWQAGRGREAIAMLSRTLADGERVLGVNHPSTVLTRENLLALARRQDPAP
                     PDRDLPQREAAQDNSSRRESSDGVSGSAV*"
ORIGIN
        1 atggaagcgc tgcccttgcg tgtggtggtc gccgacgacc aggccctggt ccgcaccggg
       61 ttccggctga tcctggagtc ggaggggatc gaggtggtcg ccgaggcgga ggacggcgag
      121 caggccgtct ccgccgtccg ccggtgccgg ccggacgtcg tcctgatgga catccggatg
      181 cccgggctgg acgggctgga ggccacccgc cggatcctcg ccgaccccgg ggaggaaccg
      241 ccgcggatca tcatgctgac caccttcgac ctcgaccact acgtctacgc ggcggtggcc
      301 gccggggcga gcggcttcct gctcaaggac gtcaccccgg agcacctggc ggcggccgtc
      361 cggctggtcc gcaccgggga cgcgctgctc gcccccgcga tcacccgccg cctggtcgag
      421 cgcttcgcgc gtccgcaggc ccgggaaacc gccaccccgc accgggagtt gggcacgctc
      481 accccgcgcg aactggaggt gatggcgctg ctcgcccgcg gcctcagcaa cgccgagctc
      541 gccgcccggc tgcagctgtc cgaggcgacg gtgaagacgc acgtggcccg gatcctcggc
      601 aagctgggcc tgcgggaccg ggcccaggtg gtggtcgcgg cgtacgagac ggggctggtc
      661 agcgtgggcg ccgcgcccga ggcgccgtaa acgcccgagg tgccgtaacg gcgcgcggga
      721 gcccgggggt cgaaaccccc aggctcccgc cctcaccggc tcgcgaggat cggaccaggt
      781 cgaatcagac caggtcgaag cggtccgcgt tcatgacctt ggtccaggcc gcgacgaagt
      841 ccgtcacgaa cttctccttg gcgtcgtcgc tcgcgtacac ctcggcgacg gcccgcagtt
      901 cggcgttcga gccgaagacc aggtcggccc gggtgccggt ccaggtgacc ttgccggagg
      961 cgtcccgcgc ctcgaaggtg tgcgagtcct ccgaggtggg cgcccaacgg gtgtccaggt
     1021 ccagcaggtt gacgaagaag tcgttcgtca gcacgccggg ggtcgaggtg agcacgccat
     1081 gcgcggaccc gccgtggttg gcgccgagca cgcgcaggcc gccgaccagg acggtcagct
     1141 cgggggcgct caggcccagc aggttcgcct tgtcgagcag caggtactcg gcgggcagcc
     1201 ggttgccctt gccgacccag ttgcggaagc cgtcggcctt cggctccagc gcggcgaagg
     1261 actcggtgtc ggtctgctcc tgcgacgcgt ccacccgccc gggcgcgaac ggcacctcga
     1321 cggcgaggcc ggccgccttg gccgcctgct cgacgccgac gccgccggcc agcaccacca
     1381 ggtcggccag cgagacctgc ttgccgtcgg cctgcgcgtt gaagtcgttc cgcacgccct
     1441 ccagggtgcg cagcaccgag gccagccggt cgggctcgtt gacctcccag ccgatctgcg
     1501 gctgcagccg gatccgggcg ccgttggcgc cgccgcgctt gtcgctggag cggaaggagg
     1561 aggccgccgc ccaggcggtg gagaccagtt cggtcaccga caggccggtg gcgttgatcc
     1621 gccgcttgag gtcggcgacg tcggccgcct cgacctgccg gtacgaggcc tgcggcagcg
     1681 ggtcctgcca gagcaggtgc tcgcccggga cctcggggcc gaggtagcgg acgaccgggc
     1741 ccatgtcgcg gtgggtcagc ttgtaccagg cgcgggcgaa ggcgtccgcg aactggtccg
     1801 ggttctccag gaagcgccgg gagatcggct cgtagaccgg gtcgaggcgc agcgacaggt
     1861 cggtggtcag catgatcggg acgtgccgct tgctcgggtc gtgggcgtcc gggacggtgc
     1921 cctcgccggc gccgtccttc ggcttccact ggtgggcgcc ggccgggctc ttggtgagct
     1981 cccactcgta gccgaacagg gtctcgaaga agctgttgtc ccaggtgatc ggggtgggcg
     2041 tccaggcgcc ctccaggccg ctggtgatcg cgtcggcgcc gacgccggtg ccgagggtgc
     2101 tcttccagcc gaggccctgc tgctcgatcg gggcggcctc cgggtccgcg ccgacgttgt
     2161 cggccgggcc ggcgccgtgg gtcttgccga aggtgtggcc gccggcgatc agcgcgacgg
     2221 tctcctcgtc gttcatcgcc atccggtaga aggtctcgcg gatgtcgcgg gcggcggcga
     2281 tcgggtccgg gttgccgttg gggccctcgg ggttgacgta gatgaggccc atctggacgg
     2341 cggccagcgg gttctccagc tcgcggtcgc cggtgtagcg ctcgtcgccc agccaggtgg
     2401 tctccgggcc ccagtagacg tcctcgtccg gctcccactc gtcgacccgg ccgccgccga
     2461 acccgaaggt gcggaagccc atgccctcca gggcgacgtt gccggtcagg atgatcaggt
     2521 cggcccagga caggctgcga ccgtacttct tcttcaccgg ccacagcagg cggcgggcct
     2581 tgtccaggct ggcgttgtcg ggccagctgt tcagcggggc gaagcgctgc tggccgccgc
     2641 cggcgccgcc gcggccgtcg ctgatccggt aggtgccggc gctgtgccag gccatccgga
     2701 tcatgaacgg gccgtagttg ccgtagtcgg ccggccacca gtcctgggag ctggtgagga
     2761 cctcctggat gtcccgcttg acggcgggga ggtcgagcgc gttgaaggcc gccgcgtagt
     2821 cgaagtccgc tccgagcgga ttggccacgg cggggttctt ggcaaggatc ttcaggttga
     2881 gccgttccgg ccaccactgg cggttcccgc cgccctgggt ggggtgcggc gcacgcccgt
     2941 ggttcaccgg gcagccctcc gccttcgcct ctacgccggt tgcatcgtgg atgtcagaca
     3001 tgggaatcct tccctcacaa ggcggatcac ggtgtcttct ctagctacct tcggcacctg
     3061 ctggtgctgt ctggagccgc gtgccacgtg ttgctgctgc gtcctacagc aacgggagcc
     3121 acgtgctgct gctacccagg ctagcgccgg agccgatcct acgatggacg caatccaagt
     3181 caagaaagac accaaaccca tatccgatcg ggatccggat gccacaggat gtgtattggt
     3241 aaactccggt cctccccttg acctgaatag gtgaaccgat atgagtgacc tgctggagcg
     3301 gctgcgcggg cgcggctggc gcctcacgtc ccagcggcgt gtcgtggccg aggtcctgga
     3361 cggcgagcac gtgcacctga ccgccgacga ggtgcacgcc cgggcggccg cacgcctccc
     3421 ggagatctcc cgggcgacgg tctacaacac cctcggcgag ctggtcaccc tcggcgaggt
     3481 catcgaggtc gccaccgacg ggcgcgcgaa gcgctacgac cccaacgcgc accgcccgca
     3541 ccagcacctg gtctgcaccg gctgcggcgc catccgggac gtccaccccc tcggcaaccc
     3601 gctcgccgac ctcccggcgg agcagcgctt cgggttcacc gtctcgcagg ccgaggtcac
     3661 ctaccggggg ctctgcccgg actgcacggg ctgaccggtc gcggcccggc cgttccgggc
     3721 cgatcggtca cggcctgact gttccgggcc gatcggtcac ggcctgactg ttccgggccg
     3781 agcagcccgg cggccgcagg tccggttctc gcttcccccg cgaaaccagg acgtgtagtg
     3841 tcccggttat gcgcatgggc gagggagtcg agtggggcct gcactgctgc ctcacactgg
     3901 cgtggctcgg ggacgagcag ccggtgccga caggacggct ggccgcctgg ttcgacctcc
     3961 cgcccgccta cctgaccaag cgcctccagg cactcgtccg ggccggcatc ctcggctcca
     4021 cgccgggcgc ccgcggcgga ttccggctgg gccgcccacc ggagtcgatc accctgatgg
     4081 acgtggtcgc cgccatcgag ggcaccgacg acctcttccg ctgcaccgag atccggcagc
     4141 gcacggaagg ggctgccgcc gccggggacg acttccggcg gccctgcggc gtgtcgacgg
     4201 cgatgcgcag ggccgaactc gcctggcggc gtgaactcgc cgggcagacg gtggccgacc
     4261 tgatggccgc ggcgcccgcc ggtgcggccg agcgcacccg ccggcactac gcgcgactga
     4321 cgggctgagc cctcccccct tgactttctg cggactgctt tcgcggcccc gcacaccacg
     4381 tgtcgacctg tgaggtgaac ctggatgtcc gatgtcctga tttcgaaggc cccgccccgc
     4441 accaccggcg ggctgtccgc caccctcgtc ctggccctgg gcaccttcgc cgtcggaacg
     4501 gacgcctgcg tggtggccgg cttcctgccc tccatggccg aggacctgca cgtctcgccc
     4561 gccacggcgg gccagtcggt caccgtcttc gccgccgcct acgccgtcct gtccccgctc
     4621 ctggcgaccc tgctggcgcg cctgccccga cgcaccctgc tcatcgcggc gctcaccgca
     4681 ctcggcctgg ccaacctcgg ctcggcactc gccccgacca ccgccgccct gctcgccacc
     4741 cgcgtcctcg ccgcagccgg cgccgccgcc tacacgccca acgcgggagc cgtcagcgcc
     4801 gccctcgtcc gccccgaact gcgggcccgc gccctcgcgg tggtgatcgg cggactgacc
     4861 gtcgccaccg cgatcggcgt gccgctcggg aacgccgccg agcactggtt cggctggcgc
     4921 accgccctgg ggctggtcgc cgggctgtgc ctggtggtgg ccgccgtgct gcgcgccgtc
     4981 atgccgcggc tgccggggaa cgcccgggtg ccgctgcgca ccaggctcgc cgtcctgcgg
     5041 cgaccggccg tgctcaccgt cctgccgctc accgtcctgg gcatgggcgc gagttacacg
     5101 gcgtacgcgt acagcgtgcc ggtgctggag gccgtcgggg tgtccggcgg ctcggtgctc
     5161 tggatgctcc tcctgtacgg cgccggggcg gtggtcggca acctcgccgc ggggtgggcc
     5221 accgaccgct ggggctccgt cacggtcctg accgtcgggt acggcaccat gacggccgcg
     5281 ctcggcctgc tggcctggct ggccgcagcc ggggcctcgg cggtgccgcc ggtcggactg
     5341 ctggtgctgc tctggggcgc cgccagctgg tgccagacgc cgccgcagca gcaccggctg
     5401 atcgggctcg cgccgcagga ggcgcccctg ctcgtctcgc tcaactcctc ggccatctac
     5461 gccgggatcg ggctcgggac ggtgctcggc ggcgccaccc tcgcatccgg tgcggccgtg
     5521 gtgtacgggc tcggcgcggg cctcgcggcg gcggcgctgc tgttcctgcg ctgcagcgcc
     5581 cgctcctgat ggatcgtcac atggcgccgc agggcccgtc acacctgcga tacagcggcc
     5641 cccgggtgca ggagtcagag gcggcgggcc tgccgcacca tcgagcgggt gatcagcacg
     5701 ccggtggcca ccgcgatgcc ggccagcacc agcatccacg gccaggccgt cccgaacccg
     5761 aacagggccg cgtcacgcag gcagcggatg ccgtaggtga cggggtcggc ccaggacagc
     5821 caccgcagca gcggggccat ctgttccacc gggtagaagg acggggcagc gaagagcagg
     5881 acgggcgcca ggacgttgat ggtgaccgtg aaccgctgga agtccttgaa ggccgtcgcg
     5941 agcaggaggt agaggccgtt gaaggcgacc gaggccagca cggtcgccag cagcagcgcc
     6001 gcccagtggt cggccggcca gcggaaggag aacaggacac cggccagggc cagcgccgcc
     6061 agggtctggg ccaggacgag cgcggctccg gccgtgagtt tggccgtgat gtagctgccg
     6121 cgcctcagcg ggtacgacca cagctcgacg tccatgttcc ccatccgctc ctggaacagc
     6181 gaggcgccgg ccgtggtcgc cgcggcgagc atcgaggaga gcagcagggc cgggacggtg
     6241 aactcggcgt agccgaaggg ccgcccctgg taccggacgt cgccgatcag ccgcgacagc
     6301 gaggtggcga acagcagcag gtagacggcg ctgggggtga tggcgaggag caggttggtc
     6361 cggttgcgcg tgagcaggca gtactcccgg tacagcacgg cgaggacgtc gtgctgccag
     6421 gtcctccgtc cggcctccgc ctgccgcggt acggcggtgg ccggggcggt cgcagcggtg
     6481 tcagaggtct cggtggtctc ggtggtctcg gtggccccag gggtcttggt ggtcgaggtg
     6541 gtcgaggtgg tctcaacggt cacggcggtt ctccacgagc tccaggaagg cgtcttccag
     6601 cgacggtgtg cggaactcca ccggggcgct ccggccctcc ggggaaccga gccgggccat
     6661 gacgcccggc agcaggtcgc ggaccccgcg cccggtgatc cgcaccgcgc cgtccgcggc
     6721 tacggcgctg agtccggcct gctcggccag gccggccagg cgcgccgagt cctccgggtc
     6781 gacgggccgc accagggccg tctggttgcc gaagcgctcg gcgaggtccg ccggtgagcc
     6841 gtgctccagc agtcggccac ggtcgacgat cagcacccgg gcgcagttgc gctccagttc
     6901 ctcgacgtag tggctggtcc acagcacggt cgtgccgtcc tgctcccgca gttcgcgcag
     6961 cagttcccag atccggcggc ggccgctgac gtccagtccg gcggagggtt cgtcgagcag
     7021 cagcagccgg ggccggccga gcagggcccg gacgacctgg agccggcgct tctctccgcc
     7081 ggagagggtg aagaccagtt gggagagcgc gtccttgagg ccgagggcgt cgagcagttc
     7141 atagcaggcc ggtcgggcgt tgcgccagcg aacgcccttg aggacggcgg cgatccgcag
     7201 gttgtccagg acggtcagca tcatgtcgaa gggcgcggac tggtggacga ccccgatgtc
     7261 gagcttggcc cgcccgccgt gtgccgaggg cccggcgccg aagacggtga tccggcccgc
     7321 ggtgggcacg gcggcgccgc agagcagctt ggtgagcgtg gtcttccccg cgccgttcgg
     7381 cccgaggagt ccgacgaccg agcccggttc gatggtgaag gagagtccgt cgacggcgtt
     7441 gcgctgcatg ccctcgtacc gcttgacgag gttctcggcc tgtacggcgg cggtcatcgg
     7501 gggcaccctc cgtcggtgtc ggtcagcggg gtggcggcgg ccagcgcgga agcggcggtc
     7561 accgcggcag cggccagcac ggcggcggtc ggcgaggcgg cggcggcagg cggggcgggc
     7621 cgcagggcgc ggacgcggtc ggcggcgaag tcgagcgtgg cggccaggcc gggcgggtcg
     7681 agcgggctgc cgaagcggag gtggaggtcg gcggtgtcgg gcggcagcag cggccgtccg
     7741 ccgtcggccg cctgcgggta gccgaacgag tagcccacca ggatggtgag gtcgcgtcct
     7801 ccggcggcgc gcagcacggt gtccagcgcc tcgggcggca gggcgccgaa gggggagatc
     7861 ccgatcaccg gcccggcgag gcgcccgggg cgctcgcact gccggacgtc caggtccgtc
     7921 gaccggtgtc cggccaccgg gccggggatc agcagccggg tgcggcccgg ccctcggtcg
     7981 tggtcgtggt cgcgctcgcg ctcgcgggga agtggcccga gtgccgagag ggcgggctgc
     8041 cgcggcggca ccgcggcgtg gtactcgggc accacgccca ggtagccgtc cggtcccacg
     8101 acggggtcga gcagcggaag gttgtcgccc gcggtcagta ggacgtccgg ggcggtcgcc
     8161 accacccggt gcacgatgat ccgtgcgccg atgacggcgg cgaccacgtc gcccgggacg
     8221 acccggggca gcggcagtgc ttccacggtg acgaccgtcc ccggcgcgat ggccggcagc
     8281 atgctctcgc cgcgggtccg cagtctcgcc ctcccggcgg cggcgagcac ggcgcgcagc
     8341 acgaccgcct ccgacggccc ctcaggcgtg tgccgcaccg gactcctcct ggaccagacc
     8401 ctccgcgacc agccgggcca cgaactcgct gatgtcacgg gtgatcagcg cctgctgcgc
     8461 ggggctggtg gcgccgtacc gccggatgag ttcggcggtg gcgtcctccg ccgagcggtc
     8521 ctcggagagc aggatccaga tctcggcggc ggtgctgttg agggtctgga actcgccgat
     8581 ccgggcggag tagagccgca cctcgccgtc agagcgggtc cacacgacct cggggtcgat
     8641 ccggtagcgc atcggtctcg gtcctctcag ttggcgagcg gcagcaggcg gcgccccgcg
     8701 gtcttccagt cgtcgtgcac ggggtggacg gagtcgtcca ggaccagccg gggggtcatc
     8761 atcgtttcct gctcggcctt cagccgtgct ccggggacgc cggtggactc ccagatgctg
     8821 gcgatcatgg accggcgcag gatccggcag aggtggcggc cgttgcggtg gatgtccccg
     8881 gtctccgcca tgtggtacgc gcggcagccg ccgccgcagg cgccccggat gtagcagcgg
     8941 cggcagtcct tgaggttctc gcccgcgtag acgctgttgc gccgcaggtc ggcgaggacg
     9001 ggcgccgcga agatctcggc gagcggcttc cggcggacgt tgccggccag gtgctgcttc
     9061 tcggtgacga gcttgcaggg gtacacgttg cccagcgagt tgatgtagat ctcgttgccg
     9121 cccatgccgc agttacccct gatcgagcag ggcttgctcg ccttcgggcc ctccggcagc
     9181 aggttcttgg tgagcgggtt ggtccacatg aagtcgagga tcttctggta ctccccccag
     9241 ccgaagtcgt agccgtcggt cgcggcccgg ccgaggtcgg agtggttcat cagccgcacc
     9301 cgggcgatgt cgaggccgcc gacgaactcg gcgagccggt cgagcaggtc gacgttctcc
     9361 ggggtgacca cgtggttgat caccggcacg acaccggctt cgttcagcag ccgcagtccg
     9421 ttggcggtgc gggcgaacgt gcccttcccg cgggtgcgtt cgtgcatctc cgcagtgccc
     9481 ccgtcgacgc tgacggtgac caggttgaag agctcggcga tctgccgggc ggtctccggg
     9541 cggcggatga ccgtcccgtt ggtgatcatg ttgacggcca gcccgcggtc ccgcgcatgg
     9601 cgggcgatct ggaacaggtc cttgcgcagc atcggttcgc cgccggtgaa gatgaggtgc
     9661 ccgaccttca tgtcggcgat ctggtcgacc aggtcgagcg actcggcggt gtcgagctcc
     9721 ccgggcaggg ccttctcgga ggaggcgtag cagtaggggc agcgcaggtt gcagccgtcc
     9781 gtgatggcgt agtacacggt ggtcagcggc ggctcgggct cgcggatcgc gggccgtctg
     9841 ccggggaggt agaccagcca gttgagcacc agcttggcca gggtccgttc cgccgcgtcg
     9901 gtgtcctcgg tggccggcgc gggccggggc cggcgacggg ccagcgcttg gaggacccgg
     9961 gtctccggct cggagaggat gcaccaggcc gccagctcgg ggttggtgac cagccggtcc
    10021 ccgtcgttcg cgaagtacac caggtcgtcg gggacgagga ggtcgtccca caggtccagc
    10081 agcttcatcc ttgacctcgc cagtgagtga ggggtggtgc ccgagcagga gccccgggca
    10141 ccacctggtg ttctgatggc ggagcagccg gcggcggacc ccggcgttca ggtctcggcc
    10201 ggccgcggcc ggccgaccgt caggagtcgg actggccgct gccggaaccg gccagggcgc
    10261 cacaggcgca ggcgcagccc atctcggcgt cgaagtcgac cggggcgatc tccggcttga
    10321 cccaggcgct ctcgtgcatg gtgcttccct tctgtcggtg gaacgcggac acaaccggga
    10381 cgaaggacgg gggccattca tctcagctga tgcgagggaa tctatctcaa ctgaaatgca
    10441 tgtcaatgga gtgtgcggaa cgccccgagg acgtcgccga agcttccggt ccggaccggg
    10501 cccgccgtca ccggcccatc cggcgcacta cgatggccgt ccacgacatt ccgaccgagg
    10561 aggcgcagtg gcggcacccg agccgggcgc acccgcaccg acgctcgccg aacagatcga
    10621 ccggctgttc cagaccatcc gccggcccaa ccacgagccg tacagcaacg aggaggtcgc
    10681 gcgggcctgc cgggaggcca ccggggagag cttttcggcc acctacctgt ggcagctgcg
    10741 caccgggcgg cgggacaacc cgaccaagcg tcatctcgaa gcgctggcac agttcttcca
    10801 ggtcccgccc gcgtacttct tcgacgacgg gctgagcgag cagatcgcgg aggaactggc
    10861 gctgctcggc gcgctccgcg acgccggggt gcgggaggtc gcgctgcggg ccgtcacgct
    10921 gtcgcccgaa gggctcggca cgatcagcga catgatcgag gcgatcgcgc gcagagaggc
    10981 cagatcccag cgttctgact gattccgccg gcgtgccgcg cccctctacg atctagcgat
    11041 caacagcgga ccggacggcg gatccggcgg acgagggggc agctcgtggt tgttggctgg
    11101 cagcgcacgg tcggtggccg acagcagcgg gagctctggc ggcgatgtcg cagcatcgcg
    11161 gccaccctgc ccgtccggga gaccttcgac ccggacgccc tcgcggccga cctgtcggcc
    11221 cggctcggac ggccggtgga actcctgccg ctggcctggc cccccacgtc cgggccctgc
    11281 gggctgctcg tgagcaccga ccgggcggac tacatcggct acccccgcga caccaccccc
    11341 ctgcaccagc ggcacatcgt gctgcacgag gtcgggcacc tgctgtgcgg ccaccgcggc
    11401 ggcccggacg tgctcgccgg ggcgaccgcc gaaaccctgc tgccgagcct gtcgggcgag
    11461 ctgatcagac gggtgctcgg caggacgggc tacaccgaga ccgaggaacg cgaggcggaa
    11521 ctgttcgcct ccctggtgct ccaccgggcg gcccggcagg ggcgggcacc gtcggccgcc
    11581 gccggtgctc cggaggtctc ggagaccgcc gcccggctcg gttccgtctt cggcgccacc
    11641 gcgaccggga accccacggc ggccgggaac cccacggcgg ccgggagccc caccgccgcc
    11701 gggagccccg ccgcggccgg gagctccatg gcagcccccg gggcggggca ccgcgcggcg
    11761 ccggcaagac ccgcggccac ccccgggccc gacccccggt gaccgagctc gtggcctacc
    11821 tggccggcgc ggtcgccctg ctcagcgcgg ggcaccggat ccggctgatc tgggggcacc
    11881 gggcggatgc cggggcccgg tacctgatcg gcctcggact ctgcgtcggc ctgtccctgg
    11941 tcctcctctc gcgctcggcc tcccaggcgg tccggccgcc gctgaccgac ctgctcccgc
    12001 tgctcggtgg agaggcgaag ctcgcagccg ggtccttcct cgccctcatg gcgcactcgg
    12061 tgcgcccggg agaccgggcc cggcggtggg cgcgccgcca gagcgccctc tccctcacag
    12121 tgatggtggc cgccgcggcg gcgtacctgg cggccggagt acgggccggc gacggcgaat
    12181 tcaccgtgtc cgacagcgga cgggccgcgc tcaccgtcta caacgccctc ttcaccgcgc
    12241 acagcctcgt gtgcgtgggc ctgttcacgg tggtcgtcca ccggtccgcc cggcacgtcg
    12301 ggcccggcct gctcaggacc ggcctgcggg tggtcgtggc gggcggcgtc tcggccttcg
    12361 tgtggtcggc actcggcctg ttcccgctgg tcgtcgcgtt caggaccggc caccgggcga
    12421 ccgccgaggc gtcctggtcg gtgcccttcg ccctgctctc gtccgcgctc ggcatcggcg
    12481 gcgccaccct gcccggctgg ggcgcccggc tcgccgggcc cctgcggcgg ctgcgcgcct
    12541 ggcgcagcta ccgcaggatc ggaccgctct ggtcggccct gcatgccgcc cacccgcaga
    12601 tcgcgctcga cgcccgcaca cccggcggga tgctctccgt cccgctgcgc aacgccgagt
    12661 tcgcgctcta ccgccgggtc atcgagatcc acgacggccg gctggcgctg cgggcgcacg
    12721 tccacccgca ggtgccggac tgggccgccg cggcctgcgc gggcctgccg gccggccacc
    12781 cgcgggctgc ggccgtcgag gccgccgtca tcgccgcagc catcgaggcc gccgcggccg
    12841 gcctccgctt ccgggttccg gccgtcagcc ccgccccgca cccggacccc tgcgacctgg
    12901 cggccgaggt cggctggctg accgaggtat cggacgcctt cgcccgctcc gtcgccgtcg
    12961 agcggatccg ccgccgggtc cgcacggacc tctgcgggaa cccggccgcc ggggatgcca
    13021 cgcccgtgga atgacgggtc aggtgcgcgg ctgccagcgg accggcaggt gcttgaggcc
    13081 gttctggaag ttcgacacca ggcggtcggg tgccgcgccg gggaccagtg ccagcccggg
    13141 cagttcggcg aggacgtggc ggagcatcgc cgtcatctgc aggcgcgcca gctgggcgcc
    13201 gacgcagaag tgcgggccga agccgaagct gacgtggtcg ttcggggacc gcgtgatgtc
    13261 gaagcggtcg ggatccggga agacggtctc gtcccggttg gcggaggcgt ggtagaccac
    13321 caccttgtca ccgcggcgga tcgggcggcc gcccaactcg acgtcccggg cggcggtccg
    13381 ccggaagtcc accacgggcg gccagtagcg cagcatctcc tccaccgccg aagggcccaa
    13441 ctccggccgc tcgcaaagca gtcggtactg ctcggggtgg gtgagcaacg catgcacgcc
    13501 ccccggcagg gcgttgcgca ccgtctcgtt gccggcgacc gcgaacagga agaacatcgt
    13561 ctcgaactcc gcggtgtcga ggccgccctc ccgcatgcgg gccaccatgc tgccggggcg
    13621 cggctgttcg gcgaccgcgt gggcgtaggc gaacatgtcg gcgagggcgg cccgcgagcg
    13681 cggattcacc ggacggccgt ccgcggtgct ccgggcggtg gggcggtgga cgagcgccgt
    13741 ccggccgagc tcggtgaggc cgaccgtacc ggccgtcccg gccgtgccgg cgtcggcgta
    13801 gtcggcgtcc tggtagccga tcacccggtt cgcccagtcc tgcagcaact gccggtcctg
    13861 gtccggcacg cccatgatcc aggccagcgt ccgcaccggc agatcggcga cgatccggac
    13921 gaagtccgcc tcaccctgcg cgcgcacccg ccggacggca gccgccgcct gctcctcgat
    13981 gcccgcggcc aactcgccca gggcacgcgg ggtgaacgct cccgcgacga tgcggcgcag
    14041 ccgggagtgg tccggcggat cctggttgag catcatcgtc cgtgcgaact ccagatccgc
    14101 agccgagtcc gggtcccgga tctgcgtcgc gcccaggtgc gaggagaaca cggcggggct
    14161 gcgcaggacc tgcttcacct cggcgtgccg cagcaccgcc cagtaccccg gcccgcccgg
    14221 ccactccccc accgccggct cctccaccca ccacaccgga gccgccgacc gcagctcccg
    14281 gaagagcccg tacgggacgc cgtcggcgta ggtggccggg aggaagatct ggttcacgta
    14341 cgcctggtcg agggtcacgt ggatggacgg tacggcagag ctgccgagct gtcccgcagt
    14401 tccataatgg aggccattcg acacaccggg tggtgggggc ggcacaggtg cagggacagc
    14461 agggctggca ggtcaggaac ggcatcgaca acagcacggt caacggcaac accttccagg
    14521 cgcgggaact gacggtcaac ctgccgccgg ctccggcgga cgcgcagtgg ccgatggtga
    14581 tcggccggat cccgcccagg gcgagtgcgt tccagccccg ggacgagctg cggcaggcga
    14641 tcgacgcggc ccgggagcag cacgggacgg tcgtgttgag ccaggtgctg gcgggcggtg
    14701 ggggcgtcgg caagtcgcag ctcgccggac actacgcgcg tgcggccatc gatgcgggca
    14761 cgggtctggt gctgtgggtc gatgccgccg accccggcaa cgtgacgcat gtctacgccc
    14821 gtgccgctgc gacggttcgg gtcccaggac tcggcggtac ggccgaggag gacgcggaga
    14881 agttcctgac atggctcgcg tccacggacc gcagctggct gatcattctc gacaacgcca
    14941 ctgagcacac cccggagagc ctctggcctg ccaccagtcg aggcgcccgt gggcgagtca
    15001 tcgctacgac ccgccaccgg ggcgccgcca gcaccggcag cgatcgcacg ctcgtcaaca
    15061 tcggcaccta ctcccccgcc gagtccgccg cctacctgcg cgaacgaatg gaacgcgccg
    15121 gctgctccca cttcctcgac gagcacgccg ccgaactcgc cgaagccctc ggccacctcc
    15181 cgctggcgct cgcccacgcc gccgcctaca tgatcaacac gcggcgcagc tgcggccgtt
    15241 acctcgggct cttccgcgat ctcactcgca gtctggacgc ggttctcccc gcacgttcct
    15301 cggctgacgg ataccggggc ccggtgacag cggcactgct gctggccgtc gacgccgcgc
    15361 agaaggagca cccggtgggc ctcgccctcc ccgtcctcca actggccgcc ctactcgacc
    15421 cggccggcca tccacgccag ctgtggacca ccgcgccggt gctcgaccac ctcagccgca
    15481 ttcgcggcac gtccatcgcg gatgacgacg cactggacgc actcgccgtt ctgcacaact
    15541 acaacctcta caacctcgtc acactcaccg aaaccccgca ccgcgaagtc agcctccacg
    15601 cgctcaccgc ccgcgccgtt ctcggcactc cctacgaccg cgagccctac cagaacgcga
    15661 tcgccgaagg cctgatcggc ttgtggccca acgaggacta ctcgttccgc gacctcgccg
    15721 cggtcctgcg agccaacacc gatgccctga tcacacagtc cggtgacctg ctgtggaatc
    15781 tgtccaccgg cgcgcaccag ctcttcaacc gggttggcca cagcctcttg aacgcaggtc
    15841 tgtacaccgc cggcatccag cactggggcc tcgtcatcgc cgttctggaa cgtacctacg
    15901 gggcggacga cctcaacacc ctcacctgcc gcagcaacct cgccacctcc taccggcgag
    15961 ccggacgaac cgatgacgcc gtcgcgctcc aggaacgcgt cctcgccgac cacgaacgca
    16021 tcttcggcag cgaccacccc gagaccctca tctgccgcaa caacctcgcc acctcctacc
    16081 aacaggccgg acgaaccgac gacgccatca ggctccaaga acgcgtcctc gccgaccacg
    16141 aacacagtct cggcagcgac caccccgaca tcctcacctg ccgcaacaac ctcgccatgt
    16201 cccactggca agccggacgc gggagggaag cgatcgcgat gctcagccga acactggcag
    16261 atggcgaacg cgtcctcggt gtcaaccatc cctcgacggt gttgacccga gagaacttgc
    16321 tcgcactggc acgacgccag gacccggcac cacctgacag ggaccttcct cagcgcgagg
    16381 cggcccagga caacagcagc cgcagggagt cgtcggacgg ggtgtcgggg tcggcggtgt
    16441 ag
//
