LOCUS       reptomyces_RBGC_527172 16316 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_527172
VERSION     Streptomyces_RBGC_527172
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000373665.1
  ORGANISM  GCF_000373665.1
            .
FEATURES             Location/Qualifiers
     CDS             2..987
                     /protein_domains="PF08545"
                     /protein_domains="PF08541"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154499"
                     /pseudo=False
                     /translation="MTDAIGVLGTGSYLPSRIVSNEEVAGPAGVDAAWIERKTGIRSRH
                     RAAAHEATSDLAAAAAAQALAAADVDACEVSLIVVATSTPDHPQPATASLVQNLLGADL
                     AAAVDVNAVCSGFVYALAMAHGQLAAQRRGGQALVIGADVYSRILDPTDRSTAILFGDG
                     AGAVVLGPVPRGRGLYASQLRGYGADHDLIGVAAGGARLPASERTVREGGHHFRMKGRA
                     VREFVSAHVPKLVDQLLVDHDVPCDEVRHMVPHQANGVMLAELCDELALPRMTAHINVD
                     RVANTGAASVPIALDEAERAGRLAEGDTVLLAAFGGGMNSALALLER*"
     CDS             1048..2399
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154500"
                     /pseudo=False
                     /translation="MTALLPDGRPQRLLAAATMTTMLGYGIYLTAGVLYLTRGLHLPAA
                     QVGLGMSVAGAVSLALGVPIGHLADRVGARMVYPATLAVGCLSMVGLCLTRDLWAFVVF
                     ATLNAVAQAAGPAARAPLVQKYGGDRPAEFRSYLRAVTNLGIAGGSVVAAWAIERDTRA
                     AYVLIIGASAVSYAVGALTAAMLPSLAPLRSRPGPRWVALRDRPYVAITILDGLMAVQY
                     RVLSVALPLWLLGRTSAPPWTVSAVMLLNTALVVLFQVRGSKGIDSVPAGAAAFRRAGI
                     AFLVACGAMSLLPGLPSWAVVVVLLAAVTAHTVGEIWQAAGGFELSFALAPKESVGQYQ
                     GLFGMGLGLGTTLGPSVLIALCIGQGRLGWWIVGVGFALTGLAVPPVTRWAQRGTAAPR
                     PEADGEQAAPAGEHGTAPTMVAADSVEAAVPYAAAELSVAPRKCVEGTGHA*"
     CDS             2393..2961
                     /protein_domains="PF00440"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154501"
                     /pseudo=False
                     /translation="MRDAGRSERTRDLLVRVTAQVIAEGCPADAGLVTIVNRAGVSRGA
                     LYHHFPSTTELIATVYRQARCRVLAMAGALLVGPASEGLGCFLAELGGQMTDDEVVRAG
                     MQLAADGTTGPPSLRDEVLAIVRTYVRGQHGEDETASAPLVDVAELVTAGVAAVRFDAT
                     AFDSQWQLLKPLFAAAGAAPGSSPAT*"
     CDS             complement(3018..3583)
                     /protein_domains="PF00440"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154502"
                     /pseudo=False
                     /translation="VFEQRGYDAASTTEILSRTDLTRGSLYHHFPSKEAIATALMSVHE
                     DALVMPEHPVAVQAVIDLTLGFAERLQKDQVLRAAVRLATEHTSLSHGRAAPYEQSRTA
                     VYHLLRRAEQQGELLPGIDLEAAAWTIVGSFTGLQIMSQVYSGRRDLLQGVNAFWQFIL
                     PGLAAPWLLLRLRTTPAPGEADADS*"
     CDS             complement(3768..4543)
                     /protein_domains="PF00486"
                     /protein_domains="PF00072"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154503"
                     /pseudo=False
                     /translation="MTRDTADLFVPLPGRRSGAREPFAPPTAVVGHPAPAAEALRVLVA
                     ESESADADSLARELTRQGFVARSTGTGTRTLQLFTEADLVLLDLDLPDMDGLQVCRAIR
                     SVSDTPVIATSTRGAELDRVLGLQAGADDYLVKPYGIRELLARMDALMRRVRRPSPDAR
                     TVVRGPLRLDPGSREVTLEGRPVALTRKEFELLHLLVSHPDRVVTRRHLMSQVWGDSTS
                     RQFRTVDTHVSSLRGKLGSSEWIITVRGVGFRIGHP*"
     CDS             4917..5953
                     /protein_domains="PF03756"
                     /protein_domains="PF03756"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154504"
                     /pseudo=False
                     /translation="VSALTDPPHANLVDVVAPHGVRHTTPGHAVSGHAAPRYAAFAHTR
                     TLTTTVPREYVHRSAVSEVLLTGWRPAAGDAATPSFTVRAQWPRAHTLFSCVRGRQDPM
                     MIVESVRQIGALLAHAEFGVPFGHHFMMGEIAFAAEPDLLAAQATPTEVELRTVCRPQT
                     RPGGKLSGMRYDVVMVREGRELGTAHAAFQCLTPVVHRRLRGERPTTTTRPIPPAAARA
                     SVGRVCDLDVLLAQPQEMGRLRWELRVDTAHPTFFDHPVDHVPGMVLLEAARQAARSAA
                     GAPDLLLLTLDSRFLRYVELDAPCWIEVTSVERRDQGQTLVRVCGVQGGERVFTADLAL
                     QAHTA*"
     CDS             5985..6904
                     /protein_domains="PF01370"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154505"
                     /pseudo=False
                     /translation="VPVVVISGATGFIGAHTVTEAASRGVALRLMCRRPPPEPTGHITV
                     QADLADPDSLRGTCDGVDILIHCASHIGDSVEDNETVNARGTEALVREACRAGVTRVVY
                     LSTASVYGRGTFRGARPQDLPRNPGSPTSASRACAEDAVLASGGIVLRPHLVYGAGDRW
                     VAPGLVRIMRAVPATADAWASRLSLIAVSDLARLLVGAALAPRRNLTASVYHAAHPTPV
                     AAGTLMRAVAVCAGLDWPGGVACAEQVRPSPGAADGLPPALAMLLTDHFFDAEPLWQDL
                     RLPPGEDFATGFARVAPWYERAWAR*"
     CDS             6947..7122
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154506"
                     /pseudo=False
                     /translation="MKNYPPQFKADAVALYQSRPEATIRQVAADLGINSHEAGPITQRR
                     SKTRHADRVGTTG*"
     CDS             7449..8098
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154507"
                     /pseudo=False
                     /translation="VQAPATVVQLALLVLLVLPGVTYQFVRERRRGPVPGERDLGERVL
                     RAIVASIALDGLYAVVAGPALVRLARGAGGGWDGFVDRPRVVGFVAVVLFLVVPAMAAV
                     IVSLVDRQRRKARFLRTPSAWDHAFRDREPCFVRVRLKDGNWAGGWYGNRSYASSYPHP
                     AELYLESARVMGADGAFGARVRGTAGLRLRAEDFDVLEFVEPAEPATVPEEER*"
     CDS             8099..8262
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_154508"
                     /pseudo=False
                     /translation="MANEPVPRPEPDLSSEEVALLQEAVDRGYTPKRTVAEPDEAPGGP
                     AGTSNGNED*"
     CDS             8282..11784
                     /protein_domains="PF12770"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154509"
                     /pseudo=False
                     /translation="VNGLAERFWEAFHVARHSADPASVEKAIGLGRAVLAAEDVAERRL
                     VLSNLGGLLQTRYHQTGDFEFLQEAVRTVMEAYFLAYESPEDSANYANNIGMLLHTAFG
                     QNQDRGTLADALEWSRTAVDEEPSTEKAFYLGNLIVALRTAFTVTKDLASLAEAVEHAR
                     AAVECSPDDVLTARSLHFLAVVLRDWSHETGETGVVEEAVDAARRAVELTPAGSSDVLD
                     RLKNLAYLLDDRYRERGARDDLSELLRVRQTLVAHTPVTDPRHSQNLVELTTTERDWAA
                     LTGEGPKRTADWERADTEAEACGRYAAEFELTRDSALLARAIELGRSVAAATPAGHPRR
                     GVRLDHFAAALATRGEAFGDRVALAEAVMIEREAVACTSAGNPRRVQFMGNLAVNLHAL
                     FHATGELAHVVDAIDVARRAAEVTAGQDRHPHVLGILAGVLHTRFRVTGELQVLSEAVE
                     RARESVRLGASLVPGQAQRLSNLGAMLSDCFVRTGEASVLDEAIDAHRAATDVTADDDP
                     DRAVRLANLGGVLEMAYEKFGDRNALRDAIAARRASVAATAEASPHWPRYTSSLAAALG
                     DWCTNPVAPAVARREPPDPQVLAEAVGLARSAARRPEQDAYWRASSLTRVADVLALGFR
                     HLGDGDALAEALGCYREAAESAGSPTASRAEAADRWGGLAAEAGQFDVAAEGYAAAVRL
                     LPRLAGRRLGREDAQYWLGRFAGVAADAAACALAVGDEVSAVTLLESGRCVLAAQALDS
                     RSDLSGLREQAPELAERFRTLTAEFETDTTSDRVALADELDAMTDRIRALPGMERFLRP
                     PLLTDLTAQAHEGPIVYINVSRHRCDALIITADGVRSRALDGLSEETVSHRVRALHTAF
                     TEGRLIAEQAIHDTLEWLWDTVVGPVLGELGLTAEPAADGPWPRIWWAPVGSLSLLPLH
                     AAGHHRDGGPVLLDRVISSTTPTIRALGHARAGRRDDRNEPRLLVVAMPVTPDAPDLPG
                     TQAEADHLAALIPGATLLVGADATRDAVLDALPASSWAHFACHGYSDPDNPSDSHLALH
                     DHDRTPFRVLDISGLRLRNAEFAFLSACDTARTTARLSDEAIHPLAAFQIAGFSQVVGT
                     LWRVDDAVAPAFSQQIYGELIADRSGALCASAAVHRTVRQLRTKYPNLPSVWAAHVHAG
                     A*"
     CDS             complement(11893..12764)
                     /protein_domains="PF00665"
                     /protein_domains="PF13276"
                     /protein_domains="PF13333"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154510"
                     /pseudo=False
                     /translation="VTVDPFIEAEKQGGHSVKRACELLQVSRAAFYARRTDAPGPRAVC
                     DAELTEKITEVHAVSRGSYGAPRIHAALQREGERCGRRRVARLMRQRGLQGQHRRRRQR
                     TTIPDPRAAMRPDLVLRDFQPNPAKLDVRWCGDVTYIPTEEGWLYLATVIDIASRRVVG
                     WATADHLRTELVAEALRAACRSRRPGGPVIFHSARGSQYTSRDFATLASELGINLSVGR
                     TGQCWDNALAESFFATIKRELIDDRSWPSRAAAHSAIFEWIEGWYNIRRLHSSLGYRTP
                     AEFEAALAA*"
     CDS             complement(12762..13078)
                     /protein_domains="PF01527"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154511"
                     /pseudo=False
                     /translation="MSVMESMGKKKPRPRRSLTPEFKAEIVELCRRGDRSVGQVAKDFD
                     LTETAVRDWVKQAEVDTGERDGLTSDEREELARLRRENRRLREDVEILKRATAFFAKET
                     R*"
     CDS             13488..15370
                     /protein_domains="PF09848"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154512"
                     /pseudo=False
                     /translation="LLLRESARTVAVMAHDGSLYHRLTEQFVHMHGYRPGTSEARSWER
                     SIPVLVGALNDAGLGGVEVMLEYALPLNSKRADAVLAGVHPSTGEPSYVIVELKQWSQA
                     APYEDDPALCLVDAYAHPVLNPIEQVRRYCDYLVNFNGAVAEHPKRVGGVAYLHNATEF
                     GVSGLREIELDDRGQLFTAESRGEFLDHLRARLSDKHSGARAADELLAGKTVPSKQLMA
                     VAAQEVREREQFILLDEQQVAYRMVLNAVRKAKRSDHKEVVVVTGGPGTGKSVIALSLL
                     GELYREGVPALHATGSQSFTKTMRKVAGARKREVQDLFKYFNSFMTAEKNTLDVVVCDE
                     AHRIRETSANRYTSSAHRTGKPQIDELIDVARVPVFLLDEHQVVRPGEMGTVAEIKTAA
                     ERKGLICRVVPLDSQFRCGGSDAYLRWVVRLLGLEPGGSVTWDPDDRMQLLVAESPQEM
                     EAFLEERRAQGYGARMSAGYCWPWSPEPKPGDPLPPDVVIGDWARPWNLRGERAISGAP
                     QSALWATDPAGFGQIGCVYTAQGFEYDWSGVIIGPDLVWRTDRWVTDRTKSKDPVFKKS
                     TPDANVDRLIRNTYKVLLTRGMVGTVVYATDPETRDKLRELVGLERQTADV*"
     CDS             complement(15693..15862)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154513"
                     /pseudo=False
                     /translation="MRRREAPLMTMRVSRDGGQTWGRWLRFHSSDNLKPLQSSVWPPCE
                     CRRCMPGLHRM*"
     CDS             complement(15856..16316)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_154514"
                     /pseudo=False
                     /translation="MSATVKACGQRRPGREHGGTGRGCVLPADHEGHHLNGFNDAWSGD
                     LPIVDAEPARGIAGLRLLPWTGPDGKPAYTPDDNPEGMIARLADRMEREQLTAASDLLE
                     FARQTLSVTEPLTPDQSRFVVARLCDVLSNPLRVAESRGMRLTTGGADA*"
ORIGIN
        1 atgactgacg ccataggcgt actcggcacc ggctcctacc tgccctcccg gatcgtgtcc
       61 aacgaggagg tggcgggccc cgccggagtc gacgccgcct ggatcgagcg caagaccggc
      121 atccgttcac ggcaccgggc cgccgcgcac gaggccacgt cggacctggc ggccgccgcg
      181 gcggcacagg ccctggctgc cgcggacgtg gacgcctgcg aagtctccct tatcgtcgtc
      241 gccacctcca cccccgacca tccccagccg gccaccgcga gcctggtgca gaacctcctg
      301 ggcgcggacc tggcagctgc cgtcgacgtc aacgccgtgt gcagcggctt cgtctacgcc
      361 ctggccatgg cacacggtca gctggccgca caacgccgcg gcggccaggc tttggtgatc
      421 ggcgccgacg tctactcgcg catcctggac ccgaccgatc ggagcacggc catcctgttc
      481 ggggacgggg cgggcgcggt cgtgctcggg cccgtcccgc gcggccgtgg tctgtacgcc
      541 agccaactgc gcggctacgg cgcggaccac gacctgatcg gcgtcgccgc cggcggggcc
      601 cggctgcccg cctcggaacg caccgtccgg gaaggcgggc accacttccg catgaagggc
      661 cgcgccgtgc gcgagttcgt ctcggcccac gttcccaagc tggtcgacca actcctcgtc
      721 gaccacgacg tcccctgcga cgaggtgcgg cacatggtgc cgcaccaggc caacggcgtc
      781 atgctcgccg agctgtgcga cgaactggcc ctgccgcgga tgaccgccca catcaacgtg
      841 gaccgggtcg ccaacaccgg ggcggcctcc gtgcccatcg ccctggacga agccgaacgc
      901 gcgggacgtc tcgcagaggg cgacaccgtc ctcctggccg ccttcggcgg cggcatgaac
      961 agcgcactcg cgctgctgga gcgctgaccg gtgccggctg cgcctttacc cccacccacc
     1021 ctcaccgaag gaaacggaca cacctcatga ccgcgctgct cccggacggc agaccgcagc
     1081 ggctgctcgc cgccgcgacg atgaccacga tgttgggcta cggcatctat ctgacggccg
     1141 gcgtgctgta cctgacgcgc ggtctccacc tgcccgccgc gcaggtcggc ctcggcatga
     1201 gcgtcgccgg ggccgtctcc ctcgcactgg gcgttcccat cgggcacctc gccgaccgcg
     1261 tcggcgcgcg catggtgtac ccggcgacgc tggccgtggg ctgcctgtcc atggtcggct
     1321 tgtgcctgac ccgcgacctt tgggcgttcg tggtcttcgc gacgctcaac gcggtggctc
     1381 aggccgcggg acctgcggcg cgggccccgc tggtgcagaa gtacggaggc gaccgcccgg
     1441 cggagttccg cagctacctg cgggccgtga ccaacctggg gatcgccggg ggatccgtcg
     1501 tggcggcctg ggcgatcgag cgggacacac gggcggcgta cgtgctgatc atcggcgcga
     1561 gcgcggtctc ctacgcggtg ggcgcgctga cggcggccat gctgccgagc ctggcgccgc
     1621 tgcgcagccg cccggggccg cgatgggtgg cgctgcggga caggccgtac gtggcgatca
     1681 cgatcctgga cgggctgatg gccgtgcagt accgcgtgct ctccgtcgcc ttgccgctgt
     1741 ggctgctcgg ccgtacctcg gcaccgccgt ggacggtgtc cgccgtcatg ctgctcaaca
     1801 cggctctggt cgtgctcttc caggtccgcg gcagcaaggg gatcgactcc gtcccggcgg
     1861 gggccgcggc cttccggcgg gccggcatcg ccttcctcgt ggcctgcggc gcgatgtcac
     1921 tgctgccggg gctgccgtcc tgggcggtcg tggtggtcct gctggcggcg gtcaccgcgc
     1981 acaccgtggg ggagatctgg caggccgccg gaggcttcga gctctccttc gccctggccc
     2041 ccaaagagtc cgtgggccag taccagggcc tgttcggcat gggcctcggc ctcgggacca
     2101 ccctcgggcc ctccgtcctg atcgccctgt gtatcgggca gggcaggctg ggctggtgga
     2161 tcgtcggggt cggcttcgcc ctcaccggcc tcgccgtccc gcccgtcacc cgctgggccc
     2221 agcgcggcac ggcagcgccc cgccccgagg cggacgggga gcaggcggcc cccgccggcg
     2281 agcacggcac ggctcccacc atggtggctg ccgactcggt cgaggccgcc gtgccgtacg
     2341 ccgccgccga actctcggtt gcgccccgca aatgtgtcga ggggacgggt catgcgtgac
     2401 gcgggccggt cggagcgcac acgggacttg ctggtgcgcg tcacggcgca ggtgatcgcc
     2461 gaagggtgcc ccgccgacgc cggtctggtg accatcgtca accgggccgg agtgagcaga
     2521 ggagccctgt accaccactt cccgtccacc accgagctga tcgcgacggt gtaccgccag
     2581 gcgcggtgca gggtgctcgc gatggcgggg gcactgctgg tcggccccgc atccgagggc
     2641 ctggggtgct tcctcgccga gctcgggggg cagatgaccg acgacgaggt ggtccgtgcc
     2701 ggcatgcagc tggccgccga tggcaccacc gggccaccgt ccctgcggga cgaggtgctg
     2761 gcaatcgtgc gcacctatgt gcgcggccag cacggcgagg acgaaacggc gtcggcaccg
     2821 ctggtcgacg tggcggagct ggtgacggcg ggagtcgccg cggtcaggtt cgacgcgacg
     2881 gcgttcgatt cccagtggca gctgctgaaa cccctgttcg ccgcggcagg ggccgcgccc
     2941 ggcagtagcc cggcgacgtg agtgacggtg tgccgggcgg gacgcccgtt gcggcacacc
     3001 gccgacgccc ccggcctcag ctgtccgcgt ccgcctcgcc cggcgccggg gtggtgcgca
     3061 gcctcagcag gagccacggt gcggccagac cgggcagtat gaactgccag aaggcgttga
     3121 ccccttggag caggtcacgg cgcccgctgt agacctgcga catgatctgg aggccggtga
     3181 aggagcccac gatggtccac gcggcggcct cgaggtcgat tcccggcagc agctcgccct
     3241 gctgttcggc gcggcgcagc aggtggtaca cggccgtccg ggactgttcg tagggggccg
     3301 cccgtccatg ggacaaggac gtgtgctcgg tggccaaccg cacggcggca cgcaacacct
     3361 ggtccttctg caggcgttcg gcgaagccga gcgtgaggtc gatgacggcc tggacggcca
     3421 ccggatgctc gggcatcacc agggcatcct cgtgcactga catgagggca gtggcgatgg
     3481 cctctttgga ggggaagtgg tggtacagcg aaccgcgggt cagatcggtg cgggagagga
     3541 tctccgtggt gctggcggcg tcgtagcctc gctgttcgaa cacgctggca gccgcctcaa
     3601 ggatctgctg ccgcgagcgt gcccctcgct cctgtttggc catgctgcgc cccaattccg
     3661 gagaaatagt ccgacttgtt tacattgtcc cggcccggtg gtgtgggcct tcttcccggg
     3721 ctgtgggtgg tcggcgcggt cggggccggc gacacgggcg gcccgctcag ggatgcccta
     3781 tgcggaagcc gacgccgcgg accgtgatga tccactcgct cgatccgagc ttgccgcgca
     3841 ggctgctgac gtgcgtgtcg accgtgcgga actgccggga cgtactgtcg ccccagacct
     3901 gcgacatgag gtgacgcctg gtcaccacgc gatcgggatg ggagaccagc aggtgcagca
     3961 gttcgaactc cttgcgggtc agcgccaccg gtcgcccctc gagtgtgacc tcccgggaac
     4021 ccggatcgag tcgcagcggc ccccgtacga cggtccgcgc gtcgggtgac gggcggcgga
     4081 cccggcgcat cagggcgtcc atccgcgcca gcaactcgcg gattccgtag ggcttgacga
     4141 ggtagtcgtc ggcgccggcc tgcaggccca gcaccctgtc cagttccgcc ccgcgcgtag
     4201 aggtggcgat gaccggtgtg tcactgaccg accggatggc ccggcacacc tgcaacccgt
     4261 ccatgtcggg caggtcgagg tcgaggagga ccaagtcggc ctccgtgaag agctgcagtg
     4321 ttctggtccc cgttcccgta ctgcgggcga cgaagccctg ccgggtcaac tcccgcgcca
     4381 gggagtcggc gtcggcggac tcactctcgg ccacgagtac gcgcagcgcc tccgcggccg
     4441 gagcgggatg gcccaccacg gcggtcggcg gcgcgaacgg ctcccgggcc cccgagcggc
     4501 gccccgggag gggaacgaag agatctgcgg tgtcccgagt catctggtcc tcccggtggg
     4561 gcgccatcgg tgcgaggcgc atgacggcaa cttaacatac agacttatct gtttgttcgt
     4621 gaaggtggga tgcgggtccg atgagcggag gcgcttccgc gtgaacgacg gtcggcacgt
     4681 caccgaacga ttggcatccc gcgtacggca gttgagaacc ggcgaggggg agtcggacga
     4741 accgtcactg acgcgctcag ggcggtgtga agccccgcat tcgtgcatgg ggaaactttt
     4801 actgttcgta cgtacaggct tgtctgtatg ttgtcgccag ccgggatcgg cccacggggg
     4861 gtggctgaga tcaagcgact tcccctgcct tcgtcgcgac tgacaggagt cccttgtgtc
     4921 tgctctcacc gacccacccc acgcgaacct cgtcgacgtc gtcgcgccgc acggcgtacg
     4981 tcacaccact cccggccatg ccgtgtccgg acacgccgcc ccccgttacg ccgccttcgc
     5041 ccacaccagg acgctcacca cgaccgtccc ccgtgagtac gtccaccgca gtgcagtctc
     5101 ggaggtgctc ctgaccggct ggagaccggc ggcgggggac gccgcgacgc cgagcttcac
     5161 ggtgagagcc cagtggccgc gcgcacacac cctgttctcg tgcgtgcggg gccggcagga
     5221 cccgatgatg atcgtcgagt ccgtccgcca gatcggcgcc ctcctcgccc acgccgagtt
     5281 cggcgtcccg ttcgggcacc acttcatgat gggtgagatc gccttcgccg cggagccgga
     5341 cctcctggcc gcacaggcca cccccaccga ggtcgagttg cgcaccgtct gccgccctca
     5401 gacgcgccca ggcgggaagt tgagcgggat gcgctacgac gtcgtcatgg tgcgcgaggg
     5461 cagggagctg ggcacggccc acgcggcctt ccagtgcctc acaccggtcg tccaccgccg
     5521 gctgcggggg gagaggccga ctacgacgac ccggcccatt ccgccggccg ccgcgcgggc
     5581 ctcggtgggc cgcgtgtgcg acctggacgt gctccttgcc cagccgcagg agatgggccg
     5641 cctgcgctgg gagttgcggg tcgacaccgc acaccccacc ttcttcgacc acccggtgga
     5701 ccacgtcccc gggatggtgc tgctggaggc cgcccgccag gcggcgcgct ccgcggcggg
     5761 cgcacccgac ctgctcctgc tgaccctgga cagccggttc ctgcgctacg tggaactcga
     5821 cgcgccgtgc tggatcgagg tgacctcggt ggagcgacgc gaccagggcc agaccctggt
     5881 gcgggtgtgc ggtgtgcagg gcggcgagag ggtcttcacc gcagacctgg ccctgcaggc
     5941 ccacaccgcc tgaaccgtcg acgtcggaag gaggcgggcc ggcgtgccag tcgtggtcat
     6001 cagcggcgcc accggcttca tcggggcgca caccgtgacg gaggcggcgt cccgcggggt
     6061 cgccttgagg ctcatgtgcc gtcggccgcc tccggagccg accggacaca tcacggtcca
     6121 ggcggacctt gccgatcccg acagcctgcg cggcacatgt gatggagtcg acatcctcat
     6181 ccactgtgcc tcccacatcg gggactccgt cgaggacaac gagaccgtca acgcccgtgg
     6241 gaccgaggcg ctggtgcgtg aggcgtgccg ggccggcgtg acccgcgtgg tctatctgag
     6301 cacggcctcc gtgtacggcc gcggaacctt ccggggcgcc cgcccgcagg acctcccgcg
     6361 gaaccccggc tcgccgacct cggcgagccg ggcgtgcgcc gaggacgcgg tcctcgcctc
     6421 gggcgggatc gtgctccggc cccacctggt ctacggcgcc ggggacaggt gggtggcgcc
     6481 cggcctggtg agaatcatgc gcgcggtgcc cgccacggcg gacgcctggg cctcccgcct
     6541 gtccctgatc gccgtctctg acctggcccg gctgctggtg ggcgcagcgt tggcacccag
     6601 gaggaacctg acagcctccg tctaccacgc cgcgcacccc acaccggtgg ccgcggggac
     6661 actcatgcgc gccgtcgcag tctgcgcggg cctggactgg ccgggcggcg tggcctgcgc
     6721 agagcaggtg cgtccctcgc cgggggcagc ggacggcctg ccgccggcac tcgcgatgct
     6781 cctcaccgac cacttcttcg acgctgaacc cctgtggcag gacctgcgcc tgcccccggg
     6841 cgaggacttc gcgacgggct tcgcccgggt ggcgccgtgg tacgagcggg cgtgggcaag
     6901 gtagggcgga ggtgctgagg atctgagaac ggacacctcg tggtcatgaa gaactatccg
     6961 ccgcagttca aggcggacgc ggtcgcgctg taccagtcgc ggcccgaggc gacgattcgg
     7021 caggtggccg ccgatctggg gatcaactct catgaggcag gacccatcac gcaacgaagg
     7081 agcaagacgc ggcacgctga tcgcgtgggg acgacagggt gacgctgggt cgagcaagaa
     7141 ccctgcgacc gcagcctgcc gttctactca tggcgccctc cgggccgtcc cgaccatcag
     7201 caggtggaca tccgatgacg acccgtgtcc tccctacggc gagccccatc ggcccagccg
     7261 tcgtcggcta cgtccgcgcg gccctaggac agtgccccgt cccgcagatc agcaggctga
     7321 tgcggaccgc cgtagccgag gccggcccgc tgcctcgcag tagccgcgga aaggggtgtt
     7381 ccgccgatcg cggagtcgca agccagtagc ctgatcgagc ggagtccgtg agacatgggg
     7441 gtggtgagtg caggcgcctg cgaccgtcgt gcaactcgct ctgctcgtcc ttctggtgct
     7501 gcccggggtc acctatcaat tcgtccggga acgccgccgt ggtccggtgc ccggtgagcg
     7561 tgatctgggt gagcgggtgt tgcgggcgat cgtcgcgtcg atcgcgctgg acggcctgta
     7621 cgcagtggtg gcggggccgg cgctggttcg cctggctcga ggcgccggcg gcggctggga
     7681 cggcttcgtg gaccggccgc gagtggtcgg cttcgtcgcc gtggtgctgt tcctcgtcgt
     7741 gccggccatg gcggcggtca tcgtttccct ggtggatcgg cagcggcgca aggctcggtt
     7801 cctgcgtacg cccagcgcct gggaccacgc attccgcgac cgcgaaccat gcttcgtgcg
     7861 cgtgcggctc aaggacggca actgggcggg cggctggtac gggaaccggt cgtacgcctc
     7921 ctcgtacccc cacccggccg agctgtacct cgaatcggcg cgcgtgatgg gtgccgacgg
     7981 ggcgttcggt gcgcgcgtgc gcgggacggc gggcctgcgg ctgcgggcgg aagacttcga
     8041 cgtgctggag ttcgtcgaac ccgcagaacc ggcgaccgtg ccggaggagg agcgataatg
     8101 gcgaacgaac ccgtgccccg gcccgaaccc gatctctcgt ctgaagaggt ggcactgctg
     8161 caggaggccg tggaccgcgg ctacaccccg aaacgcacgg tcgccgagcc ggacgaggcg
     8221 cctgggggcc cggccggcac ctcgaacggc aacgaggact gacgggtggg aggcgggccc
     8281 gtgaacggcc tggccgagcg gttctgggag gcgttccacg tggcccggca cagcgcggac
     8341 cccgcgtcgg tcgagaaggc gatcggcctc ggccgtgccg tgctggccgc ggaggacgtg
     8401 gccgagcgcc gcttggtgct gtccaatctc gggggcctgc tgcagacccg ctaccaccag
     8461 acaggcgact tcgagttcct gcaggaagcc gtccgcactg tcatggaggc ttacttcctg
     8521 gcttacgaaa gcccggagga ctcggccaac tacgccaaca acatcggcat gctgctgcat
     8581 accgcgttcg ggcagaacca ggaccgcgga accctggccg acgcgctgga gtggagccgg
     8641 acggccgttg acgaggaacc gtccacggag aaggcgttct acctgggtaa cctcattgtc
     8701 gcgctgcgga cggcgttcac tgtgacgaag gacctcgcct ccctggcgga agcagtggag
     8761 cacgcgcggg ccgccgtcga gtgctccccc gatgacgtgc tgaccgcgag gagtctgcac
     8821 ttcctcgccg tggtcctgcg cgactggtcc catgagaccg gggagaccgg tgtcgtggag
     8881 gaggctgtcg acgccgcgcg gcgagcggtg gagctcacgc cggccgggtc gtccgacgtg
     8941 ctcgaccggt tgaagaacct cgcgtacctt ctcgacgacc gctaccggga gcgcggagcg
     9001 cgggacgatc tgtccgaact gcttcgggtc cggcagacac tggtggccca caccccggtc
     9061 accgatccgc ggcactcgca gaacctcgtc gagctgacga ccacggaacg tgactgggcc
     9121 gcgctcaccg gcgagggccc gaaacggacc gccgactggg aacgtgccga caccgaagcc
     9181 gaagcgtgcg gccgctacgc cgccgagttc gagctgaccc gggactcggc cctgctcgcg
     9241 cgggcgatcg agctgggacg ctcggtggcg gcggcaaccc ccgccgggca tccacgccgc
     9301 ggcgtgcggc tggaccactt cgctgcggcg ctggccaccc gcggtgaagc gttcggggat
     9361 cgcgtcgcgc tcgcggaggc cgtcatgatc gagcgggagg cggtcgcgtg cacatccgcg
     9421 gggaatccgc ggcgggtcca gttcatgggc aacctcgccg tcaacctgca cgcgttgttc
     9481 catgcaaccg gagagctggc tcacgtcgta gacgcgatcg acgttgctcg ccgtgccgcc
     9541 gaggtcacgg cagggcagga ccgccacccg catgtactcg ggatcctcgc cggcgtgctg
     9601 cacacccggt tccgggtgac cggcgaactg caggttctgt cagaggcggt cgagcgcgcg
     9661 cgggagtccg tccgcctcgg agcgagcctc gtccccgggc aggcccagcg gctgtccaac
     9721 ctcggcgcca tgctgtcgga ttgcttcgtc aggacgggcg aggcgagcgt gctcgacgag
     9781 gcgatcgacg cgcaccgcgc ggccacggat gtgacggcgg acgacgaccc ggaccgggca
     9841 gtgcggctgg ccaatctcgg tggtgtgctg gagatggcgt acgagaagtt cggcgaccgg
     9901 aacgcgttgc gggacgccat cgcggcgcgg cgcgcgtccg tggccgcgac tgcggaggca
     9961 agcccgcact ggccccggta cacctcgagc ttggccgctg cgctcggcga ctggtgcacg
    10021 aaccccgtcg cacccgccgt cgcgcgacgg gagccgccgg atccgcaggt cctcgccgag
    10081 gcggtcggcc tggcccggag tgcggcgcgc aggcccgagc aggacgccta ttggcgggcg
    10141 agttcactga cccgcgtcgc cgacgtcctg gcgctcggct tccggcacct cggcgacggc
    10201 gacgcgctgg ccgaggcact cggctgctat cgggaggccg cggagtctgc cggatcgccg
    10261 acggcgagtc gggcggaagc agcggaccga tggggcggtc tggcagccga ggcgggccag
    10321 ttcgacgtgg ccgccgaggg gtacgccgcc gcggtccggc tgctgccccg gcttgccggg
    10381 cgccgcctgg gccgcgagga cgcccagtac tggctcggcc ggttcgccgg ggttgccgcc
    10441 gacgcggctg cgtgcgcgct ggccgtcggc gacgaggtga gcgcggtgac cctgcttgaa
    10501 tccgggcgct gcgtgctcgc tgcccaggca ctcgacagcc gcagcgatct ttccggtctg
    10561 cgcgagcagg cacccgagct ggccgagcgc ttccggacgc tcaccgcgga gttcgaaacc
    10621 gacaccacga gcgaccgcgt ggcgctcgcc gacgagctcg acgcgatgac cgaccggatc
    10681 cgtgcgctgc ccgggatgga gcggttccta cggccgccgc tgctcaccga cctcaccgcg
    10741 caggcgcacg agggcccgat cgtgtacatc aacgtcagcc ggcaccggtg tgacgcgctg
    10801 atcatcactg cggacggggt ccggtcacgc gcgctggacg gtctgagcga agagaccgtg
    10861 agtcaccgag tacgcgctct gcacaccgcg ttcacggaag ggcggctgat cgccgagcag
    10921 gcgatccatg acacgctcga gtggctgtgg gacaccgtcg tgggccctgt gctgggcgaa
    10981 ctggggctga cggcggaacc ggcggcggat ggtccgtggc caaggatctg gtgggccccg
    11041 gtcggatcgc tcagcctgct cccgctgcac gccgcgggtc accaccgcga cggcggacct
    11101 gtgctcctcg accgcgtcat ctcctcgacg acgccgacga tccgcgccct ggggcacgcc
    11161 cgcgcgggcc gccgcgacga ccggaacgag ccgcggctgc tggtggtcgc gatgccggtc
    11221 actccggacg ccccggacct gcccggtaca caggccgaag ccgaccacct ggccgctctc
    11281 atacccggcg ccacgctcct ggtcggcgcg gacgcgactc gtgacgccgt tctcgacgca
    11341 ttgccggcca gtagctgggc gcacttcgcc tgccacgggt acagcgaccc ggacaaccct
    11401 tcggacagcc acctcgcgct gcacgaccac gatcgcacgc cgtttcgggt gctggacatt
    11461 tccgggctgc gcctgcggaa cgcggagttc gcattcctgt cggcctgcga cacggcccgc
    11521 accaccgcgc gcctgtccga cgaggcgatc cacccgttgg cggcttttca gatagccggg
    11581 ttttcccagg tggtcggcac actctggcgc gtcgacgacg ccgtggcacc agccttcagt
    11641 cagcagatct acggcgagtt gatcgcggat cgatccggtg cgttgtgcgc gtcggcggcg
    11701 gtccatcgca cggtcaggca gctcaggacg aagtatccga acctgccgtc ggtgtgggcc
    11761 gcacacgtcc acgccggcgc ctgatgacgc actccgtcgt atcggaggtc gacccgcagt
    11821 cgactcggcc aactgcgttg gtagctgtct gtgagcttgc tccgctttga cggacacgtt
    11881 cggtgtcttg gtcaagctgc gagggcggcc tcgaactcgg cgggagtgcg gtagccgagg
    11941 ctgctgtgga gtctacgtat gttgtaccag ccctcgatcc actcgaagat tgcggagtgg
    12001 gctgccgccc ggctgggcca ggaccggtcg tcgatcaact cgcgcttgat ggttgcgaag
    12061 aacgactcgg cgagggcgtt gtcccagcac tggccggtgc ggccgaccga caggttgatg
    12121 cccaactcgc tcgcgagagt ggcgaaatcg cggctggtgt actggcttcc gcgggccgag
    12181 tgaaagatca ccgggccccc gggtcggcgg ctgcggcagg ctgctcgcag ggcctcggcg
    12241 accagttcgg tgcgcaggtg gtcggcggtg gcccagccca ccacgcgccg ggaggcgatg
    12301 tcgatcacgg tggccaggta gagccagccc tcttcggtcg ggatgtaggt gacgtcgccg
    12361 caccagcgca catcgagttt ggcggggttg ggctggaagt cgcgcaggac gaggtcgggc
    12421 cgcatggccg cgcgcgggtc ggggatggtg gtgcgctggc gtcgtcggcg gtgttgcccc
    12481 tgaaggccgc gttggcgcat gaggcgggca acgcgacgcc ggccgcaccg ctcgccctcg
    12541 cgctggaggg cggcgtggat gcgcggggcg ccgtagctgc cgcgtgagac tgcgtggacc
    12601 tcggtgatct tctcggtcag ctcggcgtcg cagaccgcgc ggggccccgg agcgtcggtg
    12661 cggcgggcgt agaaggcggc acgggagacc tgcagcagct cacaggcgcg cttgacgctg
    12721 tggccgccct gcttctccgc ctcgatgaac gggtccaccg tcaccgggtc tccttcgcga
    12781 agaaagccgt ggcacgcttg aggatctcca cgtcctcgcg caggcggcgg ttctcccgcc
    12841 gcaggcgggc cagctcttct cgttcgtcgc tggtcaggcc gtcccgctcg ccggtatcga
    12901 cctcggcctg cttgacccag tcccgcaccg cggtctcggt caggtcgaag tccttggcga
    12961 cctgaccgac cgagcggtca ccgcgacggc acagctcgac gatctcggcc ttgaactccg
    13021 gcgtgagcga gcggcgagga cgcggcttct tcttccccat gctctccatg acagacatct
    13081 tccttccggg gcgcaaaccc ctgatctcag gtgtccgtca aagaggaccg agcccagtcc
    13141 cgccgaagtt ccccgacggc tggcgggccc accagccgtg ctgcagcacc tgggacggcc
    13201 ggagtacagc gtcgcggttg actgaacgga ccgcgggcta cccggaccga acggatctca
    13261 agacggaccc gggtgcgtga ggctccgggc gtcagacgtg atcagggcga ggacaccgag
    13321 cgataccgaa agaccgccgg caaacaagaa ccttcaccgc cgccagcctc atgagtaccc
    13381 ttgatcacat cattgcggcc cgacgggctt ccgctccgct ccggtggagt ctcgaaggac
    13441 atgcccccac ccgcacgagt cacttcgtgc tgcctggggg aattccttgc tgctccgcga
    13501 gtcggccagg acggtcgccg tcatggccca cgacgggtcg ctctaccacc gcctgaccga
    13561 acagttcgtc cacatgcacg gctatcgccc ggggacctcc gaggcccgct cctgggagcg
    13621 cagcatccct gtgctggtgg gggcactcaa cgatgcgggg ctcggcggtg tggaggtcat
    13681 gctggagtac gcgctgccgc tgaacagcaa gcgggccgac gccgtgctcg ccggggtgca
    13741 cccgtccacc ggagagccgt cttacgtcat cgtcgagctg aagcagtgga gccaggcggc
    13801 cccttacgag gacgacccgg ccctctgcct ggtggacgcc tacgcccacc ctgtgctcaa
    13861 ccccatcgag caggtgcgcc gctactgtga ctacctggtc aacttcaacg gagccgtcgc
    13921 cgagcacccc aagcgggtcg gcggcgtggc ctacctccac aacgcgaccg agttcggggt
    13981 cagcggcctg cgcgaaatcg agctcgacga ccgcggtcaa ctgttcaccg ccgagtccag
    14041 aggcgagttc ctcgaccacc tccgtgccag gctgagcgac aagcactcgg gggcccgtgc
    14101 ggccgacgag ctccttgcgg gcaagacggt cccctccaag cagctgatgg ccgtggcggc
    14161 gcaggaggtg cgggagcgag agcagttcat cctcctcgac gagcagcagg tcgcctatcg
    14221 catggtgctc aacgcggtgc gtaaggcgaa gcggtccgac cacaaggagg tcgtggtcgt
    14281 caccggcggc ccggggaccg gcaagagcgt catcgcgctc tccctgcttg gcgagctgta
    14341 ccgggagggc gtgccggctc tgcacgccac cggttcgcag tccttcacca agaccatgcg
    14401 caaggtcgcc ggcgcccgga agcgggaggt ccaggacctc ttcaagtact tcaacagctt
    14461 catgacggcc gagaagaaca ctctcgacgt cgtggtctgt gacgaggccc accgcatccg
    14521 cgagacctcc gcgaaccgtt acacctcgtc tgcccaccgg acgggcaagc cgcagatcga
    14581 cgagctcatc gacgtcgccc gggtgcccgt cttcctcctc gacgaacacc aggtggtgcg
    14641 tcccggtgag atgggcaccg tggcagagat caagacggct gccgaacgaa aggggctaat
    14701 ctgccgcgtc gtgccgctcg acagccagtt ccgctgcggc ggcagcgatg cctatctgcg
    14761 gtgggtcgta cggctgctcg gtctggagcc cggcggttcg gtgacgtggg atcccgacga
    14821 ccgcatgcag cttctggtcg ccgagagccc gcaggagatg gaggcgttcc ttgaggagcg
    14881 tcgcgctcag ggttacggcg cccggatgtc ggctggctac tgctggccgt ggtcaccgga
    14941 gcccaagccc ggcgacccgc tcccgccgga cgtggtgatc ggcgactggg ctcgcccctg
    15001 gaacctgcgc ggagaacgcg cgatttccgg agctccgcag tcggccctat gggcaaccga
    15061 tccggccggc ttcggccaga tcggctgtgt ctacaccgcg cagggtttcg agtacgactg
    15121 gtccggcgtc atcatcggtc ccgaccttgt ctggcgcaca gaccgctggg ttaccgaccg
    15181 tacgaagtcc aaggacccgg tcttcaagaa gtccacgccc gacgccaacg tggaccggct
    15241 gatcaggaac acctacaagg tcctgctcac tcgaggcatg gtcggcacgg tggtgtatgc
    15301 gactgacccg gagacgcgcg acaagctgcg cgagctggtg ggtctggagc ggcagactgc
    15361 cgacgtctga cggagtgagg tccttggaca gcgggttctg tggcggcccc ggtcgaagag
    15421 ggggagcggc tcacgagaga gtcagggagg cgaccaggag gaggccgccg cacggcttgg
    15481 cgcaggtggg cgatcggctg gcctgcgaca gtcggtcgcc ccgcgtggac atcacgatgc
    15541 gcagtacccg tgcgtggagt cgtgcagcag gcatcgcact cattctgtgc ttgggagctc
    15601 tgaggccacg agacgaaccg ggcaccaggg ccccgtagcg accagggaat cggcaggtcg
    15661 ctacagggcc cctctctgct cggccggctc gctacatgcg gtgcagtccc ggcatgcatc
    15721 ggcggcactc gcacggtggc cacacggagg attggagggg cttgaggttg tcgctgctgt
    15781 ggaagcgcag ccagcgcccc cacgtctgcc cgccgtcgcg cgatacgcgc atagtcatca
    15841 gtggagcttc gcgcctacgc atcggcgcct ccggtcgtca gacgcatgcc gcgtgactcg
    15901 gcgacccgta gcgggttcga caggacgtcg caaagacggg ccacgacgaa acgagattgg
    15961 tccggggtca gcggctcagt aacggagagc gtctgacggg caaactcaag caggtctgac
    16021 gctgcggtga gttgttcacg ttccatgcgg tcggcgagtc gcgcgatcat gccctcggga
    16081 ttgtcgtccg gggtgtaggc gggcttcccg tccggcccgg tccacgggag cagtcgcagg
    16141 cccgcgatgc cgcgcgcagg ctccgcgtcc acgatcggca ggtcgccgga ccacgcgtcg
    16201 ttgaagccgt tcaagtggtg cccttcgtgg tctgctggca ggacgcagcc gcgtccggtg
    16261 ccgccgtgct cgcgtccggg gcggcgctgt ccgcaagcct tcacagtcgc gctcat
//
