LOCUS       reptomyces_RBGC_607548 16662 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_607548
VERSION     Streptomyces_RBGC_607548
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001425805.1
  ORGANISM  GCF_001425805.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1668
                     /protein_domains="PF00501"
                     /protein_domains="PF13193"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240527"
                     /pseudo=False
                     /translation="MTVDLHDLLPAELRRSWTVDGTCPDLDLYSLYRARQVADLHRTAV
                     LDAKGKLCYTALDRKVRCLAAGLSGLGIRAGDVVGIQLPNGRSAVIADLALAALGAVAL
                     PFPVGRGEREAASLLRRAEAVAVIAATEHRGNHHAADLLPLTSELPALHTVIAAGPGTA
                     PEGAVAFSALLRTDPTSFTAARPAPDSAARILVSSGSEAEPKMVAYSHNALAGGRGNFL
                     ASLIPDDQPPRCLFLVPLASAFGSNGTAVTLARHGGTLVLLDHFTPEAALDALAEHEPT
                     HVLGVPTMIRMMLDRIAEGHHPAFTPPTAVIVGGSPLDEATAEEARRVFGCPVVNLYGS
                     ADGVNCHTGLGDEPLRGEGPGILAGHPDPRVADIRIAVPGASEFEEAPKGTVGEIVARG
                     PMTPLCYVAAPDLDARYRTADGWVRTGDLGLIEDDGNLRIVGRLKDVVIRGGANISPAE
                     VEVELATHPLVRDVVCVGVPDPLMGERLAACVVPRGKAPTLANLSSHLDARGLERRKHP
                     ERLLILAELPLTPAGKPDRALLREQCSTKAPESLAQAV*"
     CDS             complement(1746..2566)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240528"
                     /pseudo=False
                     /translation="MARIRVRIARVPSVLALSLSTALVLTATACGSDKADSADTNTSGK
                     NDDAPVVVATTTWEGALAKAAGAKDVKVIVPSSAQHAPDYDPTPSDLAAVAGADFVLYA
                     PFEPYAAKIKEAGGSSAKLVEVNLDNDADKTSAEVTRLGKLFGTQDAAAKWDTSFKSEY
                     GTLQKELKEAWPNGKAPTVLAQVFSVWSAKMAGAEVVGTYGPDAVTAKQLSELAKKKPA
                     YVFDNVHMTTGEVLPDSGAKQVEILNYPGKDLELLAVYKNAADTITKAMAS*"
     CDS             complement(2516..3393)
                     /protein_domains="PF00950"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240529"
                     /pseudo=False
                     /translation="VNSLATADLWPLLQLIPVQRAGAALLLAAIGLPVIGVVIVGLDIM
                     PVRFAMMHVALLGIAIGLLTGLDPMLCALVACALAGAGVAPLARTPDGLSGAMGLLMSL
                     AIAAALLVLSVSGVNAQGAFALLWGSILSVGTADLWLLGTLAVVVPALLWWRRRDLALL
                     LYDRELALSAGVRVDLLTLLLLVLVAMSVAGAIKLTGALLVDALTLLPALAARRLGTSL
                     KSITAWAVGIGVTVNLTGFLLALKLDWPPGPVLVLTAGAVVLAVHLIPERRISSWRASA
                     SASPVSLPSSH*"
     CDS             complement(3391..4025)
                     /protein_domains="PF00005"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240530"
                     /pseudo=False
                     /translation="MDGLDVRMREVACRHGRVEAVRGVDLDIEAGERVALTGTNGSGKT
                     TLIRAVLGLHRQADGRILVGGRGTGTAAEWAWRRRACAWIPQKPAVGRFPLLAHELLAS
                     SGAQAEAVEAAEKLGVGALTERPLHTLSGGQLQRMYLARAVGCVAAGAGVLLADEPTAA
                     LDFAGQEEAADVLLSLPVTVVVVTHDRALADRCDRVLEMAAGSLREAR*"
     CDS             4395..4612
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_6240531"
                     /pseudo=False
                     /translation="MADVNPEPIATFCGNCNCGCPQLFLDSDAPEDKRVRITDDFGQQV
                     QMSEEQFADLVAQAKAGALDQLTVASA*"
     CDS             complement(4841..5361)
                     /protein_domains="PF04314"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240532"
                     /pseudo=False
                     /translation="MTEQSLWRPSRRRLTDTLLAALAPVAACGLALGGLSTWTAYGNAG
                     SPARITVTEGRVFLPTGDSTETAAFFRITNSGGSEDRLLKVTSAEAGGDTSLSRHRMVT
                     DNTASSQTVTSVPVPAGDSLAMSPSGLDVLVPANAEWQAGDLVAFTLHFERSGAVENLA
                     VVVRPGQDGA*"
     CDS             complement(5359..7628)
                     /protein_domains="PF00122"
                     /protein_domains="PF00702"
                     /protein_domains="PF00403"
                     /protein_domains="TIGR01525"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240533"
                     /pseudo=False
                     /translation="MGAEPVTVLVTTDLTVGGMTCAACVTRVEKKLGKLEGVTASVNLA
                     TGRARVSHPVEISPEELVATVEKAGYTAALPQPPKKRQHEEENGEPNSHEARQERDRLL
                     ITALLALPVLVLSMVPALQFRNWQWLCFVLAAPVALWGAWPFHVRAVRGLRHSAATMDT
                     LVSLGVIASFAWSSYALFLGGAGDPGMRMPFSLVPSASEGVAHIYLEAAVAVPLFVLAG
                     RFLEARARRGTGAALRALAGLATKEVSVREGDGSERLIPVEELGVGQVFVVRPGERVAT
                     DGQVAEGSSAVDLSLVTGESEPVEVGPGSAVVGGAVNAGGLLLVRATAVGADTQLARIT
                     RLVTEAQAGKAKAQRLADSVAGVFVPVVLTLAATVLGFWLGAGADPQAAVTACVAVLVV
                     ACPCALGLATPTALMAATGRGAQLGVLVSGPRALEGLQHLDVVVLDKTGTLTSGHMSVA
                     RVTVVPGALGRDVVLRLAGAVEQGSEHPLGRAIAAYARRVLPERPLPEVSGFTAVPGRG
                     VHGRVEGRLVEVLAPDHELPAALAEAMPAAETAAHTPVLVRVDGVTEALIEVGDVVRPG
                     SYRAVDRLRRLGVKPVLATGDREAPAQAVAKALGIDEVHARCTPEDKARLVRDLQEQGY
                     RVAVIGDGVNDAAALAGADLGIAMGTGTDVAIGAADLTLVRGDIEALADAVRLARRTLG
                     TIRVNLVWAFGYNVVTVPLAMVGLLNPMLAAAAMSVSSLLVVGNSLRLCAWQPSPAARK
                     GSR*"
     CDS             complement(7629..7888)
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_6240534"
                     /pseudo=False
                     /translation="MHESRQSSTGAGVVLRKLMPPPVLCGFLLLLAMVFAVSYAAGSAA
                     GPVAPGMHGTSDSTGGGGTGGTGDSGDTGDMGEMDLHGGGH*"
     CDS             complement(8067..8812)
                     /protein_domains="PF07987"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240535"
                     /pseudo=False
                     /translation="MSTTRITLRRVGLVTALAAVGVLTAAGVAAAHVTVHPDSYAKGAT
                     DGVLTFRVPNEEDTAATTKVQVFLPTDHPVLGVLVSPQDGWTAKVTNTKLETPVKTDDG
                     TITDAVSEITWTGGKVGAGQYEDFNVAFGQLPDDTDQLTFKTLQTYSDGKTVRWIEQAE
                     SGGEEPENPAPVLKLTAKGADDAGGSASTTSSAAPKSAGSSTATASGSDSTARGLGIAG
                     LIVGVLGLAAAVFAVVRGRFDGSRGE*"
     CDS             complement(8854..9452)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240536"
                     /pseudo=False
                     /translation="MAASADMSASLEVRSLRAAVFAVLCVLLAAGVHVLATGVAPPVWT
                     QVAGAVLVFTAGCLLGARERTLVGIGGGTLAAQGGLHLVFGAARPHAAMAVHGMRMTHA
                     HALTPHATAAHVGAAVVLAWWLRRGEAALWSLLRWAVAFVPGLAAWWQVAGGVRGGPVV
                     PRPVCRAAGEDRPLRQLRLRYAVHRRGPPKGMSYVI*"
     CDS             complement(9521..11004)
                     /protein_domains="PF00561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240537"
                     /pseudo=False
                     /translation="LSRRTALWWTLAATAALLPPIPAQAATPHEPALPFGACPDSVPRP
                     AAPDRVECGRISVPLDWNRPQGPHIEVAVSRVPASGTPAEHRGILLVNPGGPGGSGLPY
                     AVTKRAKLPGSVRRAYDIIGFDPRGVGQSTPVDCGPMGGLFDSPGADPVPVGPVAERAY
                     LASLRNTADDCSAGAGAMLPYLSTEQTARDMDAIRTALGEPRTNFLGVSYGTYLGAAYA
                     AQFPHRTGRMVLDSVVGPWNWYDFDVIQSRALLRQRDTFFTWTAAHPDRFALGGSADAV
                     RRAYLRVREGLTARPVAGFGPAEFDRAVYRALGRTERWAGLADGLRTYLRDDSPDALRP
                     ATAFDSPDSRTYEAANRIVKCADAPAPTPHRILADIRRTRHLDPQPVLTGMEASTCAYW
                     HHRPAQPTPLGSPDAPPLLLVASAHDPVTTIGGAHELRRLLPGSRLVTLDNDYSHGVFA
                     SRGNACVDEAAAAYLVDGTVPTANVRCTGPGLPAVP*"
     CDS             11167..12407
                     /protein_domains="PF13535"
                     /protein_domains="PF18603"
                     /protein_domains="PF18130"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240538"
                     /pseudo=False
                     /translation="MVESWVGSMSRLLPRAIREGGHEFTFLTRDLHHYLRAAPEGAAHP
                     LLGARNVITADTNDTDTLLPEIERLHAVLHFDGVITSCDYYLPTAAEIAGHLGLPGSSP
                     EAVANACRKDATRRVLADAGVPGPRFAVHEEWADIARAAREIGYPLVVKPVDLCAGMYV
                     RRVDDEEQLAATVRALADFPVNARGQRRQPGVLIEELLDGPEVSVETVSHAGAVHVVGV
                     TDKSIGGAPAFIETGHMFPAALPAADAEAAEQTALASLKALGLVDSVVAHTEIKLTSAG
                     PRVVEVNPRPAGNRITELVRHVTGVDLAAAFVEVSLGREPDLRHSDTGLRSAAIGFLVP
                     QTSGTLESLDGGELRDAPGVLEVQLAEPGKQVEAAGSNNEYLGHVMAGDAEGLGARDHV
                     EVLLGELRSGLVIR*"
     CDS             12405..13276
                     /protein_domains="PF04016"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240539"
                     /pseudo=False
                     /translation="MTAVAGISRTTAAEPYETCDSYDELVARVRAGELGPDPATQRIAV
                     AFTTRQAVRHDGRGTGYRNEVLSLRLGGAVGSCAVEPGALPDRAVEECVGASVARLLEH
                     PLLPVRVAALDAYLMHVTAHTPRNGARPVMLSAGTSLEKSRARAKAVVALLDLPADATV
                     LVVGVVNSLLEALRSRRLSYVPCDLKGGLTEWEEAVVTDALAEAGRCDALLVSGMTLGN
                     GTFEPLRRHALAHGKQLVMFAQTGSAVLPRFLGHGVSAVCAEPYPFFWLDGSPGTLHRY
                     GGPCPEGGR*"
     CDS             13274..14361
                     /protein_domains="PF00291"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240540"
                     /pseudo=False
                     /translation="MTTTAVRPLARPELLALLGRTPLVRITADLPGPHPGFWAKLEGLA
                     AGGMKARAAVSMLLGARERGELRPGAPVVESTSGTLGIGLAFAGQALGHPVVLVGDSEL
                     EPSMRQLLRAHGVRLEIVDRPAPRGGWQAARLGRLRELLAVLPGAYWPDQYNNPDNSAG
                     YASLAAELIDRLDDLDILVCSVGTGGHSAGIIGPLRRRWPALRLIGVDSTGSTIFGQPA
                     RPRLMRGLGSSIHPRNVAYDAFDEVHWVGPAEAVDSCRRLARGSFVSGGWSTGAAARVA
                     AWAARVHPGAVVATVFPDGPHRYLGTVYDDDFATAHCLDPATAATRPVEIPHPRAAEAT
                     GWVRCTRVADPLKAVPHPERTP*"
     CDS             14359..15416
                     /protein_domains="PF13378"
                     /protein_domains="PF02746"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240541"
                     /pseudo=False
                     /translation="VKASLRTAPLELTEPLRISRSTMTARDAVWLTVEHDGVTGHGEAV
                     TSVYYGLDAETLKRLLTAVGTELTRFPDPECALAALRAGEPAGENTPPAVTAATEAALL
                     DLVGKRAGSPVHRLLGAAAPPVAATARTIGITSLAHAAAQARCLAASGFEVIKVKAGTP
                     DPEDDVERVRVIRDAAPRARLLLDPNGAWTVAQAEALLHRFADLGVEAVEQPLAPGDPE
                     ALGTLAERSPLPVIADEDAVDLEDVRRLAGRVQGVNVKLAKCGGVHAALRIAELIEGSG
                     TELMLGCLTASSLGLAPAVHLSDRARWADLDGHLLLAHDPWTGIGGEGGVVRVSDRPGL
                     GVQEVGAYEDVA*"
     CDS             15401..16662
                     /protein_domains="PF07690"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_6240542"
                     /pseudo=False
                     /translation="MKTWREMRRFPLAVQLLLVNQLGVNTGFYLLIPYLATHLTDNLGM
                     SAAVVGIVLGVRNLSQQGLFIIGGSASDRLGARGVIIAGCALRTAGFALFALGDNLAVL
                     LAASVLSGLAGALFNPAVRTYIAQEADERRAEAFALFNVFATTGALIGPLLGSALLLVD
                     FRTSALTAAGIFAALTVAQALVLPARKVEPSKGTVLADWREVLGNRAFLAFALAMVGMF
                     TLENQLYLLLPDGARQATGWDGAAGLVFLVGTLANLALQLRITRALKERGNRARWIATG
                     LGLMALAFLPPAVVTVGSNGPVGAADAVLRALPVLVGALLLYLGVMVAQPFVMELIPGF
                     GRPELTGTYFGIFYVVSGIAAAVGNTVIGWAMDSGERGDAGWLPWACCALFGLASALGV
                     AWLHRLGSLPSPSKPAIPATA*"
ORIGIN
        1 atgaccgtgg atctgcacga cctgctgccc gccgagttgc gccgctcctg gacggtcgac
       61 ggcacctgcc ccgatctcga cctgtacagc ctctaccgtg cccgccaggt cgccgacctg
      121 caccgcacgg cggtcctcga tgccaagggg aaactctgtt acaccgccct ggaccgcaag
      181 gtgcgatgtc tggccgccgg gctgtccggg ctcggcatac gcgccggtga cgtggtcggc
      241 atacaactcc ccaacggtcg tagcgccgtc atcgccgacc tcgcgctggc cgcgctgggc
      301 gctgtcgcgc tgcccttccc ggtcggccgg ggcgagcggg aggcggcctc gctgctgcgc
      361 agggcggagg cggtcgctgt catcgccgcc accgagcacc gcggcaacca ccacgccgcc
      421 gacctgctcc cgctgaccag tgagctgccc gccctgcaca cggtgatcgc cgccgggccc
      481 ggaacagccc ccgaaggcgc cgtcgccttc tcggcgctgc tgcgcaccga ccccacatcc
      541 ttcaccgcgg cccgccccgc ccccgactcc gccgcccgca tcctggtctc ctccggctcc
      601 gaggccgagc cgaagatggt ggcgtactcg cacaacgccc tggccggcgg ccgcggcaac
      661 ttcctcgcct ctctcattcc cgacgaccaa ccgccgcgct gcctcttcct cgtgccgctg
      721 gcctccgcgt tcggcagcaa cggcaccgct gtgacgctcg cccggcacgg cggaacactt
      781 gtcctgctcg accacttcac gcccgaggcg gccctggacg cgctcgccga gcacgagccc
      841 actcacgtcc tgggcgtgcc gaccatgatc cggatgatgc tggaccggat cgcggaggga
      901 caccatccgg cgttcacgcc gccgacggcc gtgatcgtcg gcgggtcacc gctggacgag
      961 gccactgccg aggaagcccg gcgggtcttc ggctgtccgg tcgtgaacct ctacggttcc
     1021 gccgacggcg tcaactgcca cacaggactg ggcgacgaac ccctgcgcgg tgaagggccc
     1081 ggcatcctcg cgggccaccc ggacccacgc gtcgcggaca tacgcatcgc cgttcccggc
     1141 gcatccgagt tcgaagaggc accgaagggt accgtcggcg agatcgtggc ccgcggcccg
     1201 atgaccccgc tgtgctatgt cgcagccccc gacctcgatg cccgctaccg caccgccgac
     1261 ggctgggtac gcaccggcga cctcggcctc atcgaggacg acggcaacct gcgcatcgtc
     1321 ggccgtctga aggacgtcgt catccggggc ggggccaaca tcagcccggc cgaggtggag
     1381 gtcgagctcg ccacacatcc gctcgtacgg gacgtggtgt gcgtcggggt gccggacccg
     1441 ctgatgggcg agcggctcgc ggcctgcgtc gtgcctcgag gcaaggcgcc caccctggcg
     1501 aacctgtcct cgcatttgga cgcgcgcggc ctggagcggc gcaagcaccc cgaacggctg
     1561 ctgattctcg ccgagttgcc gctgaccccg gcgggcaagc cggaccgggc gctcctgcgg
     1621 gagcagtgct ccaccaaggc tccggagtct ctcgcgcagg ccgtctgacc cgtacgagtg
     1681 cggggccgcc gggagactcc cggcggcccc gcactcgtct caggacgaac tcctcgtcat
     1741 gaggtcaaga agccatcgcc ttcgtgattg tgtccgccgc gttcttgtac accgccagca
     1801 gctccaggtc cttgcccgga tagttgagga tctccacctg cttggccccc gagtcgggca
     1861 gcacctcgcc ggtcgtcatg tgcacgttgt cgaagacgta cgcgggtttc ttcttcgcca
     1921 gctcggacag ctgcttggcc gtcacggcgt caggcccgta cgtgcccacc acctccgcgc
     1981 ccgccatctt cgccgaccac acggagaaga cctgcgcgag gaccgtcggg gccttgccgt
     2041 tcggccacgc ctccttcagt tccttctgca gcgtgccgta ctcgctcttg aaggatgtgt
     2101 cccacttggc ggcggcatcc tgggtcccga acaacttgcc cagccgggtg acttccgcac
     2161 tcgtcttgtc tgcgtcgttg tcgaggttga cctcgaccag cttcgcgctc gacccgccgg
     2221 cttccttgat cttcgccgcg tacggctcga agggcgcgta gagcacgaag tcggcgcccg
     2281 cgaccgccgc gaggtcggac ggcgtggggt cgtagtccgg ggcgtgctgc gcggacgacg
     2341 ggacgatgac cttcacatcc ttcgcgccgg cggccttggc gagggcgccc tcccaggtgg
     2401 tggtggccac gacgacggga gcgtcgtcgt tcttcccact cgtgttcgtg tccgcgctgt
     2461 cggccttgtc ggaaccgcac gcggtggcgg tcaggacgag cgccgtgctc aggctcagtg
     2521 cgaggacgga agggacacgg gcgatgcgga cgcggatgcg cgccatgagc tgattctccg
     2581 ttcggggatg agatggacgg ccaggaccac agcgcctgcc gtcaggacga gcacgggccc
     2641 gggtggccag tcgagcttca gcgcgagcag gaacccggtg aggttcacgg tgacgccgat
     2701 gccgaccgcc caggcggtga tggacttcag ggaggtgccc aggcgccgcg cggcaagcgc
     2761 gggcagcagg gtcagggcgt cgacgagcag cgcgccggtc agtttgatgg ccccggccac
     2821 ggacatcgcg accagaacga ggagcaggag ggtgagcagg tcgacgcgca cccctgcgga
     2881 gagggcgagt tcgcggtcgt agagcaggag ggcgaggtcg cggcggcgcc accagagcag
     2941 ggccggtacg acgacggcga gcgtgcccag cagccacagg tcggcggtgc ccacggacag
     3001 gatcgagccc cacagcagcg cgaacgcgcc ctgcgcgttg actccggaca cggacaggac
     3061 cagcagtgcg gcggcgatcg ccaggctcat cagcaaaccc atcgcgcctg acaggccgtc
     3121 cggagtgcgg gcgagcgggg cgaccccggc acccgcgagg gcgcaggcga cgagcgcgca
     3181 cagcatgggg tcgagcccgg tcagcagtcc gatggcgatg cccagaaggg cgacgtgcat
     3241 catcgcgaac cgcaccggca tgatgtccag cccgacgatc acgacaccga tcacgggcag
     3301 gccgattgcc gccaacagca gtgcggcacc ggcccgttgg acgggtatga gttgaaggag
     3361 gggccagagg tcggcagtgg cgaggctgtt caccgggcct cccgcaggct gccggcggcc
     3421 atctccagca cgcggtcgca gcggtcggcc agcgcgcggt cgtgcgtgac gaccacgacg
     3481 gtcaccggca gggacagcag gacgtcggcg gcctcctcct gcccggcgaa gtcgagcgcg
     3541 gcggtgggct cgtcggccag caacacgccg gccccggcgg cgacacaacc gaccgctcgc
     3601 gccagataca tgcgctgcag ctggcccccg gacagcgtgt gcagcggtcg ttcggtcaac
     3661 gccccgacgc ccagcttctc cgccgcctcc acggcttcgg cctgtgcacc gctgctggcc
     3721 agcaactcgt gtgccagtag cgggaaacgg cccaccgcgg gcttctgtgg tatccaggca
     3781 cacgcccggc gccgccacgc ccactccgcc gccgtaccgg tgccccggcc gccgaccagg
     3841 atccgcccgt cggcctggcg gtgcaggccc agcaccgctc ggatcagcgt ggtcttgccc
     3901 gacccgttgg tgccggtcag cgcgacccgc tcaccggcct cgatgtcgag atccacaccg
     3961 cgtacggcct cgacccggcc gtgccggcaa gcgacttcac gcatccgaac atccagaccg
     4021 tccatcccac ctcctgctca ttccccgaaa ggagtcggag gaggcggccc gtgagttccc
     4081 ggcgaacagg cgaattcgcg aagacttgcg gcaacgtctc ggcacctgca cccaccggca
     4141 ccgtgaccgg caccgatgtc gacgacgcgc gtgcgcgagc cgcggtcgtc gaaggaggct
     4201 tcgttgtcac tcgacccggt accaacacca tcagcacaca acccaccctt cacaggtcat
     4261 tcggcggtgg cgcgcagatc ccgccaactg acatggcttt cctcatgcgt tggggccgtt
     4321 tcggcttggc tgcgcgccgg gcatccttga agtgccggat cgtccggcgc gcggaagcga
     4381 caaggcggca cccatggctg acgtgaatcc ggaaccgatc gcaaccttct gcgggaactg
     4441 caactgcggt tgtccccagc tcttcctgga ctcggacgca cccgaggaca agcgggtgcg
     4501 catcaccgac gacttcgggc agcaggtgca gatgagcgag gagcagttcg ccgacctcgt
     4561 ggcccaggcc aaggccggcg ccctggacca gctgaccgtg gcgtcggcct gacgccggtg
     4621 tgtccgtggg agacaccctg ctcctcgacg ccctgctgtg cgaggacgtc ggggagctcg
     4681 acgtggtgcg cccgcgagag gttctgagtt ctgggctgtc cacatcgcac cacgtccggc
     4741 aggtctcctg acgtcggatt cctcctcgta ggccggcacc gtcagctgcg tgaggacgac
     4801 cgcccggggg cgctcgtcga cagtgcgtcc atagggtatc tacgcgccgt cctggcccgg
     4861 gcggaccacc acagcgaggt tctccacggc cccgctgcgt tcgaagtgca gcgtgaacgc
     4921 gacgagatca ccggcctgcc actccgcatt cgccggcacg agcacgtcga ggccggacgg
     4981 ggacatggcg aggctgtcgc cggccgggac gggcaccgag gtcaccgtct gactggatgc
     5041 cgtgttgtcg gtgaccatac ggtggcggct gagcgaggtg tcaccgccgg cttcggcgga
     5101 cgtcaccttc agtagcctgt cctccgagcc tccgctgttg gtgatccgga agaaggccgc
     5161 tgtctccgtg ctgtcgccgg tcggcaggaa gacccgcccc tcggtgaccg tgatccgggc
     5221 cggactgccc gcattgccgt acgcggtcca cgtgctcagg ccgccgaggg cgagcccgca
     5281 ggcggcgacg ggcgcgagcg cggcgagcag ggtgtcggtg agccggcgac ggctcggccg
     5341 ccagagggac tgctcggtca tcggctcccc ttccgggccg cgggcgaggg ctgccaggcg
     5401 cacagccgca ggctgttgcc gaccaccagc agcgaactga ccgacatcgc cgccgcggcg
     5461 agcatcgggt tgagcagacc gaccatggcg agcggcacgg tcacgacgtt gtagccgaag
     5521 gcccacacga ggttgacgcg gatcgtgccc agcgtgcgcc gggccagccg tacggcatcc
     5581 gccagggcct cgatgtcacc gcgcacgagc gtcaagtcgg ccgctccgat ggcgacgtcg
     5641 gtgcccgtcc ccatggcgat gccgaggtcc gcgccggcca gcgcggcggc gtcgttcacg
     5701 ccgtcgccga tgaccgcgac tcggtacccc tgctcctgca gatcccgtac gaggcgggcc
     5761 ttgtcctcgg gagtgcagcg ggcgtgcact tcgtcgatgc ccagggcctt ggcgacggcc
     5821 tgggcgggtg cctcccggtc gccggtggcg agcacgggct tcacgccgag gcgccgcagc
     5881 cggtccacag cccggtagct gccgggccgt acgacatccc cgacctcgat cagcgcctcg
     5941 gtcacgccgt ccacgcggac cagcacgggc gtgtgtgcgg cggtttcggc ggccggcatc
     6001 gcctccgcca aggcggcggg caactcatgg tccggggcaa gcacttcgac cagccgcccc
     6061 tcgacgcgac cgtgcactcc ccgcccgggc acggcggtga acccactcac ctccggcaac
     6121 ggccgctcgg gcagtacccg ccgggcgtac gcggcgatcg cccgacccag cgggtgctcc
     6181 gagccctgct cgaccgcccc cgccagccgc agcaccacgt ccctgcccaa ggccccgggt
     6241 acgaccgtga cccgggcgac actcatgtgc cccgaggtga gcgtgccggt cttgtccagt
     6301 acgaccacgt ccaggtgctg gagcccctcc aacgcccggg ggccgctgac caggacgccc
     6361 agctgggccc cgcggccggt ggcggccatc agggccgttg gcgtggccag tcccagcgca
     6421 cacgggcagg ccacgaccag gacggccacg cacgcggtga cggcggcctg cgggtcggcc
     6481 ccggcgccga gccagaaacc gagcactgtg gcggccagcg tgaggacgac ggggacgaag
     6541 acaccggcga ccgagtcggc cagccgctgt gccttcgcct tgcctgcctg cgcctcggtc
     6601 accagccggg tgatccgggc gagctgggtg tccgcaccga cggcggtggc ccgtacgagc
     6661 agcagcccgc cggcgttgac cgctcccccg acgaccgccg atcccggacc gacctcgacc
     6721 ggttcgctct cccctgtgac cagggacaga tccacggccg aactgccctc cgccacctgc
     6781 ccgtcggtgg ccaccctttc cccgggacgt acgacgaaga cctgcccgac gcccaactcc
     6841 tcgacgggga tgagccgttc ggagccgtcg ccctcgcgga ccgacacctc cttggtcgcg
     6901 aggccggcca gcgcccgcag tgccgccccg gtcccgcgcc gagcccgtgc ctccaggaac
     6961 cgccccgcga gcacgaacag cggcacggcg acggccgctt cgaggtagat gtgcgcgacg
     7021 ccttccgacg ccgagggcac caggctgaac ggcatgcgca tgccgggatc accggcgccg
     7081 ccgaggaaga gcgcgtagga ggaccacgcg aaggaggcga tcacgccgag cgacaccagg
     7141 gtgtccatgg tcgccgccga gtgccgcagc ccccgtaccg cccgcacgtg gaacggccac
     7201 gcaccccaca aggccaccgg cgcggccagc acgaaacaca gccactgcca gttgcggaac
     7261 tgcagcgcgg gcaccatcga caggacgaga acgggcagtg cgagcagggc cgtgatcagc
     7321 agacggtcac gctcctgccg ggcctcgtgg gagttcggct ccccgttctc ctcctcgtgc
     7381 tgccgcttct tcggcggctg gggcagggct gccgtgtagc cggccttctc gaccgtcgcg
     7441 acgagttcct cggggctgat ctccaccgga tggctcaccc gggcccgccc ggtcgccaga
     7501 ttgacgctcg ccgtgacccc ctccagcttg ccgagcttct tctcgacgcg tgtcacacag
     7561 gccgcacagg tcatgccgcc gacggtcaga tccgtcgtca ccaggacggt caccggttcg
     7621 gcacccatca gtggcctccc ccgtgcaggt ccatctcccc catgtctccc gtgtccccgc
     7681 tgtcgccggt gccaccggtc ccgccgccgc cggtgctgtc ggacgtgccg tgcatgccgg
     7741 gcgcgacagg tccggcggcc gacccggcgg cgtacgacac cgcgaacacc atggccagca
     7801 gcaggaggaa cccgcagagc acgggcgggg gcatgagctt tcgcagcacc acacccgcgc
     7861 cggtggaaga ttgtctggac tcgtgcatca ccgggtctcc agatcgcgtc gtgcgacgtc
     7921 cgtggatcga gccgcaccgc tttcaggagt cggaacggcc gagggccggg ttccgaagca
     7981 gaggtatggc gtgcgtcaca tgcaacgcgg ccgtgtccat ggagggtggc ccggccggcg
     8041 ggttgccgcc ggccgggcag gcgctctact cgccccgcga tccgtcgaac cggccgcgta
     8101 cgacggcgaa caccgccgcc gctagcccca gcacgcccac gatcagcccg gcgatgccga
     8161 gcccgcgggc cgtcgagtcg ctgccggacg cggttgccgt ggagctgccg gcactcttcg
     8221 gggccgccga cgaggtggtc gaggcgctac cgcccgcatc gtccgcgccc ttggccgtga
     8281 gcttgaggac cggcgccggg ttctccggct cctccccgcc cgactccgcc tgctcgatcc
     8341 agcggacggt cttgccgtcg gagtacgtct ggagggtctt gaaggtcaac tggtccgtgt
     8401 cgtcgggcaa ctgaccgaag gcgacgttga agtcctcgta ctgacccgct ccgactttcc
     8461 cgccggtcca ggtgatctcg gagacggcgt cggtgatggt gccgtcgtcc gtcttgaccg
     8521 gcgtctcgag cttcgtgttc gtgaccttgg cggtccagcc gtcctgcggg gagacgagca
     8581 cgccgaggac ggggtggtca gtgggcagga agacctgcac cttcgtggtg gcggcggtgt
     8641 cctcctcgtt ggggacccgg aaggtgagga ctccgtcggt ggcgcccttg gcgtagctgt
     8701 cggggtggac agtgacgtgc gcggcggcga cgcccgcggc ggtgagtacg ccgacggcgg
     8761 ccagcgcggt gacgaggccg acgcggcgca gggtgatgcg tgtcgtggac atgggtgtgt
     8821 gggtctccgt actgaggaag ggggtgtcgg ggtcagatga cgtacgacat ccccttcggc
     8881 ggcccgcgcc gatgtacggc gtagcgcagc cgcagctgac gcagcggccg atcctcaccc
     8941 gcagcccggc acaccggacg cggcacgaca ggtccgcccc gtactccgcc cgccacctgc
     9001 caccaggcag cgagccccgg cacgaacgcc accgcccacc gcaacagcga ccacaacgcg
     9061 gcctcaccgc gccgcaacca ccaggccagc acgacggccg ccccgacgtg cgcggcggtg
     9121 gcgtgcgggg tcagggcatg ggcatgggtc atccgcatac cgtgcacggc catcgcggcg
     9181 tgcgggcggg cggcgccgaa cacgaggtgc agcccgccct gagccgccag cgtcccacca
     9241 ccgatgccga ccagggtccg ttcccgcgcg cccagcaggc atccggccgt gaagacgagc
     9301 acggccccgg cgacctgcgt ccacaccggc ggcgccacgc cagtggccag cacatgtact
     9361 ccggcggcga gcagcacgca cagcacggcg aacaccgccg cgcgcaggct ccgtacctcc
     9421 agggacgcac tcatgtccgc cgatgctgcc atgcgacccg aagacctctc tcctcgcccg
     9481 accggatgaa gacgaacttg tcaagcagtc tggaatgtgt cacggcaccg cgggcagtcc
     9541 gggccccgtg cagcgcacgt tcgccgtcgg aaccgtcccg tcgacgaggt acgcggccgc
     9601 cgcctcgtcc acgcaggcgt tgccgcggct ggcgaagacc ccgtgggagt agtcgttgtc
     9661 gagcgtgacc aggcgggagc cgggcaggag gcggcgcaac tcgtgcgccc cgccgatggt
     9721 ggtgacgggg tcgtgggcgg aggccaccag caggaggggc ggggcgtcgg ggctgccgag
     9781 cggcgtgggt tgggcggggc ggtggtgcca gtaggcgcag gtggacgcct ccatgccggt
     9841 caggacgggc tgggggtcga ggtgccgggt gcggcggatg tccgccagga tccggtgcgg
     9901 ggtgggtgcg ggggcgtcgg cgcacttgac gatgcggttg gcggcttcgt aggtgcgtga
     9961 gtcggggctg tcgaaggcgg tggcggggcg gagggcgtcg gggctgtcgt cgcgcaggta
    10021 ggtgcgcagg ccgtcggcga ggccggccca gcgttcggtg cggcccaggg cgcggtagac
    10081 ggcgcggtcg aactccgccg ggccgaagcc ggcgaccggc cgggcggtga gtccttcgcg
    10141 gacgcgcagg taggcccggc gtaccgcgtc cgcgctgccg cccagcgcga agcggtccgg
    10201 atgggcggcg gtccaggtga agaacgtgtc gcgctggcgc agcagtgccc ggctctggat
    10261 gacgtcgaag tcgtaccagt tccaggggcc gacgacgctg tcgaggacca tgcggccggt
    10321 gcggtgcggg aattgggcgg cgtaggccgc gccgaggtag gtgccgtagg agacgccgag
    10381 gaagttcgtc ctcggttcgc cgagtgccgt gcgtatcgcg tccatgtccc gggcggtctg
    10441 ctcggtcgag aggtacggca gcatggcgcc ggcgcccgcc gagcaatcgt cagccgtgtt
    10501 ccgcagtgac gccaggtagg cgcgttccgc caccggtccg acggggacgg ggtcggcgcc
    10561 cggactgtcg aagagaccgc ccatcgggcc gcagtcgacc ggtgtgctct gtccaacacc
    10621 gcgcggatcg aagccgatga tgtcgtacgc acggcgcacg ctcccgggga gtttggcgcg
    10681 tttggtgacc gcgtagggca ggccggagcc gcccgggccg ccgggattga ccagcaggat
    10741 gccgcggtgt tctgcggggg tgccagaggc gggtacgcgc gagaccgcca cctcgatgtg
    10801 cggtccctgg gggcggttcc agtcgagcgg gacgctgatc cgcccgcact cgactcggtc
    10861 cggggccgcg ggcctgggca cggagtcggg gcaggcaccg aaggggaggg ccggctcatg
    10921 aggggtcgcg gcttgggcgg ggatcggggg cagcagggcg gcggtagcgg caagggtcca
    10981 ccacagggcg gtgcgacggg acaagggtct ctccggaagg ggctcggcaa gggactagta
    11041 aatgaaaatg attatcgcta gcgtatgcgg agcgcaaagc ccggcccctc ccgcccgagg
    11101 gctctccggg ctgccctgac gtctgaaccg ctggcatgaa aaggggagtt gtggctcatc
    11161 tgctgatggt cgagagctgg gtcgggtcga tgagcagact gctgccacgg gcgatccggg
    11221 aaggcgggca cgagttcacg ttcctcaccc gcgacctgca ccactacctc cgcgcggcgc
    11281 ccgagggggc ggcgcacccg ctgctcggcg cccgcaacgt gatcaccgcc gacaccaacg
    11341 acaccgacac cctgctgccg gagatcgaac ggctgcacgc cgtgctgcac ttcgacggcg
    11401 tgatcacctc ctgcgactac tacctgccga cggcggccga gatagccggg cacctgggtc
    11461 tgccgggctc gagcccggag gcggttgcga acgcctgccg caaggacgcc acccgccgtg
    11521 tcctcgccga cgcgggggtc cccgggccgc gcttcgccgt gcacgaggag tgggccgaca
    11581 tcgcccgggc ggcgcgggag atcggctacc cgctggtcgt caagccggtc gacctgtgcg
    11641 cgggcatgta cgtgcggcgc gtggacgacg aggagcaact cgccgccacc gtacgggcgc
    11701 tggccgactt cccggtcaac gcccgcggac agcgccgaca gcccggcgtc ctgatcgagg
    11761 agctactgga cggccccgag gtgagcgtcg agacggtgtc gcacgcgggc gcggtccacg
    11821 tggtgggcgt gaccgacaag agcatcggcg gggcgcccgc gttcatcgag accggacaca
    11881 tgttcccggc cgccctgccc gccgccgacg ccgaggccgc cgaacagacc gctcttgcct
    11941 cgctcaaggc actcgggctg gtggacagcg tggtggccca caccgagatc aagctgacgt
    12001 cggccggtcc gcgcgtggtc gaggtcaacc cacggcccgc cgggaaccgc atcaccgaac
    12061 tggtccgcca cgtgaccgga gtcgatctgg ccgcggcctt cgtggaggtg tccctcggcc
    12121 gcgagcccga cctgcggcac agcgacacag ggctgcgcag cgcggccatc ggcttcctcg
    12181 tgcctcagac ctcgggcacg ctcgagtcgc tggacggcgg cgaactccgc gacgcgccgg
    12241 gtgtgctgga ggtgcagctc gccgagcccg gtaagcaggt ggaggcggcg ggcagcaaca
    12301 acgagtacct cgggcacgtc atggcgggtg acgccgaggg gctgggcgcc cgcgaccacg
    12361 tcgaggtcct gctcggtgag ctgcggtccg ggttggtgat ccgatgaccg ccgttgccgg
    12421 catatcccgc acgacggcgg ccgaaccgta cgagacgtgc gactcgtacg acgagctggt
    12481 ggcgcgcgtc cgcgccggtg agctgggtcc ggatccggcc acgcagcgga tcgcggtggc
    12541 cttcaccacg cggcaggcgg tacggcacga cgggcgcggc accggctacc gcaacgaggt
    12601 cctcagcctg cgtctgggcg gagccgtcgg ctcgtgcgcg gtcgagcccg gggcgctgcc
    12661 cgaccgtgcg gtcgaggagt gtgtgggcgc gagcgtggcc cggctgctgg agcatccgct
    12721 gctgccggtg cgcgtggccg cgctggacgc ctatctgatg cacgtcactg cgcacacgcc
    12781 acggaacggg gcgcggcccg tcatgctgtc cgccgggacg tcgctggaga agtcccgggc
    12841 ccgggcgaag gccgtcgtcg cgctgctcga tctgccggcg gacgcgaccg tgctggtggt
    12901 gggtgtcgtc aactcccttc tggaggcgtt gcgttcacgc cgcctgagct atgtgccttg
    12961 tgacctcaag ggcgggctga ccgagtggga ggaggcggtc gtcaccgacg cgcttgccga
    13021 ggccgggcgc tgcgacgccc tgctggtgtc cgggatgacg ctgggcaacg gcacgttcga
    13081 gccgctgcga cgtcacgcgc tggcgcacgg caagcagctg gtgatgttcg cccagaccgg
    13141 cagcgccgta ctgccccgtt tcctcggcca tggggtgagc gcggtgtgcg ccgagccgta
    13201 tcccttcttc tggctcgacg gcagccccgg caccctgcac cgctacggcg gcccgtgtcc
    13261 ggagggcggt cgatgaccac gacggccgta cgccccctcg cccgcccgga actgctcgcc
    13321 ctgctcggcc gcacgcccct ggtccgcatc acggccgacc tgcccggccc gcaccccggc
    13381 ttctgggcca agctcgaagg gctcgcggcg ggcggcatga aggcgcgggc agcggtgtcg
    13441 atgctgctgg gcgcccgtga gcgcggcgag ctgcggcccg gcgcgccggt ggtggagtcc
    13501 acctccggca cgctcggcat cgggctggcc ttcgcgggtc aggccctcgg tcatcctgtc
    13561 gtgctggtgg gtgacagtga actggagccg tccatgcggc agttgctgcg ggctcacggg
    13621 gtgcggttgg agatcgtgga ccgcccggcg ccccggggcg gctggcaggc agcgcggctg
    13681 ggccgtctgc gggagctgct cgccgtgctc cccggcgcgt actggccgga ccagtacaac
    13741 aaccccgaca acagtgccgg ttacgcctcc ctggccgccg aactcatcga ccgactcgac
    13801 gacctggaca tcctggtgtg cagcgtcggc accggcggcc acagcgcggg gatcatcggc
    13861 ccactgcggc ggcgctggcc cgcgttgcgg ctgatcggcg tcgactcgac cggctccact
    13921 atcttcggcc agcccgcccg gcccaggctg atgcgcggcc tgggcagcag catccacccg
    13981 cgcaacgtcg cctacgacgc cttcgacgaa gtccactggg tcggccccgc cgaggccgtg
    14041 gacagctgcc gccgcctggc ccgcggcagt ttcgtcagcg gcggctggag cacgggcgcc
    14101 gccgcccgcg tcgccgcctg ggcagcccgc gtgcacccgg gcgcggtggt cgccaccgtc
    14161 ttccccgacg gcccgcatcg ctacctcggc acggtctacg acgacgactt cgccacggct
    14221 cactgcctcg accccgccac agcggccacc cgcccggtcg agatcccgca cccccgcgcg
    14281 gccgaggcca ccggctgggt gcgctgtacc cgcgtcgccg acccgctgaa ggccgtaccc
    14341 catccggaaa ggaccccgtg aaggccagcc tgcgcaccgc acccctggaa ctcaccgagc
    14401 cgctgcgcat ctcccgctcc accatgaccg cccgcgacgc cgtgtggctg acagtcgaac
    14461 acgacggcgt caccggccat ggtgaggccg tcaccagcgt ctactacggt ctcgacgccg
    14521 agaccctcaa acggctcctc accgcagtcg gcacggaact cacccgcttc cccgaccccg
    14581 agtgcgccct ggcggccctg cgggcgggcg agccggcagg cgaaaacacg cccccggccg
    14641 tgaccgccgc caccgaggcc gcgctgctcg acctcgtcgg caagcgtgcg ggcagccccg
    14701 tccaccggct gctcggtgcc gccgcacctc cggtcgcggc caccgcccgc accatcggca
    14761 tcacctccct cgcccacgcg gcggcacagg cccgctgtct cgcggcgagc ggtttcgagg
    14821 tcatcaaggt caaggcgggc acccccgacc cggaggacga cgtggagcgc gtccgcgtca
    14881 tccgcgacgc ggcgccccgg gcccggctcc tgctcgaccc caacggcgcc tggacggtgg
    14941 cgcaggcaga agcgctgctg caccggttcg ccgacctcgg agtcgaggcc gtcgagcagc
    15001 ccctcgctcc cggtgacccg gaagcgctgg gcacgctggc cgaacgctca ccgctgccgg
    15061 tcatcgccga cgaggacgcc gtggacctgg aggacgtgcg ccgcctggcc ggacgcgtcc
    15121 agggggtcaa cgtcaagctc gccaagtgcg gcggggtgca cgcggccttg cgtatcgccg
    15181 agttgatcga aggaagtggg acggagctga tgctgggttg tctgaccgcc agcagcctcg
    15241 gcctcgcgcc ggccgtccac ctctccgacc gggcccgctg ggccgacctc gacggacacc
    15301 tgctgctcgc ccacgacccg tggaccggga tcggcggcga gggcggcgtc gtacgcgtaa
    15361 gcgaccgtcc tggcctggga gttcaggagg tgggggcgta tgaagacgtg gcgtgagatg
    15421 cgccgcttcc cgctcgcggt ccagctcctg ctggtcaacc agctcggcgt caacaccggc
    15481 ttctacctcc tcatccccta cctcgccacc cacctcaccg acaacctagg catgtcggcg
    15541 gccgtcgtcg gcatcgtgct cggcgtgcgc aacctcagcc agcaggggct gttcatcatc
    15601 ggcggctccg cctccgaccg gctcggcgca cgcggcgtca tcatcgccgg atgcgccctg
    15661 cgcaccgccg ggttcgccct gttcgcgctc ggcgacaacc tggccgtgct gctcgccgcg
    15721 tccgtcctca gcgggctcgc cggtgcgctg ttcaaccccg ccgtgcgcac ctacatcgca
    15781 caggaggcgg acgagcgcag ggccgaggcg ttcgccctgt tcaacgtgtt cgccaccacc
    15841 ggcgccctga tcggcccgct gctgggaagc gcgttgctgc tcgtggactt ccgcacgtcc
    15901 gcgctcaccg ccgccgggat cttcgccgcc ctcaccgtcg cacaggccct ggtcctgccc
    15961 gcccggaaag tcgagcccag caagggcacg gtcctcgcgg actggcgcga ggtcctgggc
    16021 aacagggcct tcctcgcctt cgcgctcgcc atggtcggca tgttcaccct ggagaaccag
    16081 ctgtacctgc tgctgcccga cggagcccgg caggccaccg gctgggacgg cgccgccgga
    16141 ctcgtcttcc tggtgggcac cctcgccaac ctggcgctgc aattgcgcat cacccgtgcc
    16201 ctcaaggagc ggggaaaccg ggcgcgctgg atcgcgacgg gcctgggtct catggcgctg
    16261 gcgttcctgc cgcccgccgt ggtgacggtc ggctccaacg gtccggtcgg tgcggcggac
    16321 gcggtgctgc gcgccctgcc cgtcctggtc ggcgccctcc tgctctacct cggggtgatg
    16381 gtcgcccagc cgttcgtaat ggaactgatc cccggtttcg gccggccgga gctgaccggc
    16441 acctacttcg gcatcttcta cgtggtctcc ggcatcgccg ccgccgtcgg caacaccgtc
    16501 atcggctggg ccatggacag cggggagcgg ggcgacgccg gctggctgcc gtgggcgtgc
    16561 tgtgccctgt tcgggctcgc ctccgcgctg ggcgtggcct ggctgcaccg actcgggtct
    16621 ctgccgagcc cgtcgaagcc tgccataccc gcaacggcct ga
//
