LOCUS       reptomyces_RBGC_616427 16866 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_616427
VERSION     Streptomyces_RBGC_616427
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000721265.1
  ORGANISM  GCF_000721265.1
            .
FEATURES             Location/Qualifiers
     CDS             complement(2..780)
                     /protein_domains="PF03372"
                     /protein_domains="TIGR00633"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750757"
                     /pseudo=False
                     /translation="MRIATWNVNSITARLPRLLAWLESSGTDVLCLQEAKTTQEQFPEQ
                     ALREIGYESAVHATGRWNGVAVLSRAGLDDVVRGLPGGPEYEGVEEPRAVAATCGPVRV
                     WSVYVPNGREVGHAHYAYKLRWLDALRGTITQDAAGERPFAVLGDFNIAPTDADVWDRS
                     AFEGATHVTADERDALAALREEGLRDVVPRPLKYDHPFTYWDYRQLGFPKNRGMRIDLV
                     YGNGPFGAAVKDSYVDREERKGKGASDHAPVVVDLDV*"
     CDS             complement(827..1512)
                     /protein_domains="PF13483"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750758"
                     /pseudo=False
                     /translation="MEVRATPAPRIPERRRSTVRFTKRGHACVRLEKDGRTLVIDPGGY
                     SEQDAAVGADAVLVTHEHPDHFDEDRLRAGLGDNPAAELWAPRSVTDKVAAAFPGRVHT
                     VGHGDTFTAAGFDVEVHGELHAVIHPDIPRIANSGYLVDGSVFHPGDALTVPERPVDTL
                     MLPVMAPWNKIAEIVDYLREVEPRRAYDVHDALLSEVARPMYDRMLGGLAGAEHGRLAP
                     GDSVEL*"
     CDS             complement(1518..2869)
                     /protein_domains="PF02627"
                     /protein_domains="PF12697"
                     /protein_domains="TIGR02425"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750759"
                     /pseudo=False
                     /translation="VSEISTQTLQYRVDGPEDAPALVLGPSLGTTWHMWDRQVPELAKQ
                     WCVVRFDLPGHGGAPAEATAAVPELAQRLLDTLDSLGVQRFGYAGCALGAAVGAELALR
                     HGERVASLALIAASPRFGTADEFRQRGVIVRANGLEPMARSAPERWFTPGFAAAQPAIV
                     EWAVQMVRTTEPACYIAACEALAAFDIRAELGSIAVPTLVLVGAEDQVTGPAEARTLVA
                     GIPDARLALVPGASHLAPVEQPAAVTDLLTDHFSTAWYNPSETTTGITLPPDRRPEPAA
                     SVPGAEGPAESEEPPQTQAQTQAQAQAQDEQEEQPEPAEPQGRPDLHDAGMRVRREVLG
                     DEHVDRATASADAFTEDFQQLITRYAWGEIWTRDGLDRRTRSVITLTALVAGGHLDELR
                     FHTTAALRNGLSPAEIKEVLLQTAIYCGVPAANAAFKVAAEVIREETRPQE*"
     CDS             complement(2883..3145)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750760"
                     /pseudo=False
                     /translation="MQAKERPAAGEGYDNGLRRVRLYDARASCLTYPAGNGVPDHLLAM
                     RAGHTDVKTTEKWYVKPDVVDLLPVAKAWGGLARGSVTDRDR*"
     CDS             3392..4056
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750761"
                     /pseudo=False
                     /translation="MTSAITQDQPAQPPKGTSRDDEPEEAGVRDEEYLYRDASRLQAGS
                     LLTTRTMARRLPALVLRSVRMAWRVDRGTTVGLLVCQTATGVFAALGLLAVTGTLTSLI
                     SSGAVVQRLWDAAPQLAVVAAATGLRALLGIAVVWLTGRLRPVLARAAEVTMVEATLGA
                     EPAANNKPGYNDAYDIADRGAQVTPDLVEEAQDVLAATATLTAGATVLTVLHPLLLPS*
                     "
     CDS             complement(4086..4231)
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MGSRLPGAAATSGAGPPPSGSGQAASPLIRRCNFQKDWKSPVCWV
                     SWA"
     CDS             complement(4398..5710)
                     /protein_domains="PF04261"
                     /protein_domains="TIGR01413"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750762"
                     /pseudo=False
                     /translation="VSAQHDGTGADGSRAARPGVSRRALFGGGLAAAGAGAGVYAGAGA
                     LFANGPAATPTRPSGELIDLTGRHPFYATADASPQAGIRTAPQRYGVLAAFDVTSSSAA
                     DLQVLLARWSASIAQLQKGNTVGLVEPAHGSGAGVDTGEALDLGPASLTVTLGLGPGIF
                     DERFGLADKRPARLAALPALPALPSDRLDAALTGGDLSLQACADDPQVAYHAIRDLTRI
                     ARGNAAVRWTVLGFGRASAGPDQATPRNLLGFKDGTRNIRTEDDYRRWVWAGSDEGWMA
                     GGSYQVVRKIQMNIEIWDADPISDQQRVFGRTKTAGAPLSGGREHTTPDFHATLPGGGK
                     AIDPTSHIALAAHENNGGLKILRRSYNYTDGINQYGQLDAGLLFIAYMNDPDHFVRLQK
                     RLGASDRLNEYISHIGSAVFAVPPAPKAGSYIGKPLFG*"
     CDS             complement(5708..6975)
                     /protein_domains="PF09375"
                     /protein_domains="PF13473"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750763"
                     /pseudo=False
                     /translation="MLSADRLPRPTRRRTAIGAVGVLTVLTLVSCSSNDSGQATASGSA
                     GTAKSGAKAGGSSAVTVTLKSGGSGDTCEASATTAKAGPVTFTVKNESATGIIEFELLQ
                     QQRIVGEKENLAPGLAPVSFTATLGGGKYQLYCPGAAKELTDFTVTGKPAPVASGSTAT
                     LLAQGAKGYSGYVTARLNDLLKGSKTLQADIDAGNLKKAKTDYAGTRQFYEKIESDVAG
                     FVKPGFKPTDNAGNLDYLIDMRASNLDQAVGWHGFHAIERDLWHGGAITPSTKKLAAEL
                     VTNVTTLEKLAPKLQFKPEDLANGAAGLLEEVQSNKITGEEEAFSHIDLADLSANVEGA
                     RQAFAYLQPGLTKIDPALTKTIQQRFSGVDTVMGKLRDAGSLGGYQRWDGATKTANAKK
                     ISQSVQALQDPLSHLAQKVATAK*"
     CDS             complement(6963..8614)
                     /protein_domains="PF03239"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750764"
                     /pseudo=False
                     /translation="MLTTFVIGLREGLEAVLIVSIIAAFLKRNGVPRRPMWCGVGLAVL
                     VSVGVGVALQALEQSLPQAKQEGLESVIGLVAVVFVTGMIVWMGKNARGLRAELEGSAG
                     AAVSRGTGWALAGMAFLAVVKEGFETAVFLLATLHASTSAGAAALGAAIGIVVACVVGC
                     ILYFGGARLNLSRFFTISGVFLVFVAAGLLLTAFRTARGAGWIDIGQQHTVDLSWLSPI
                     GSIRSALITGVLGIPADPRMIEALAWLCYLVPVLAVTLWPRRWRAAPARVPTVKFSIAA
                     AAALSAVVLPLAVPDGKPSVPTTVALTAGKGDPHHPPASSAGTASVTVRGDSASLLVHG
                     GGTTQTVRFTGAARTSADHAGVRAEQWTEHARASSSGRPSTLTIDELAALFGRVPVGIS
                     NTQNPGPYHAQWTTTTTSTLWLTHHGILDARRVDRTTLTLTGGGLGRPRTLTMTEPYWS
                     VPSAAVTATGKAVADGELTAHERTLWRLWLPAALGAAAVGLALTGRRTRRGLTRDPADS
                     PEPADGAGNPSLSTNADDEASQEPRRSTNDVVR*"
     CDS             complement(8798..9900)
                     /protein_domains="PF05425"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750765"
                     /pseudo=False
                     /translation="MGFVGLAALALVVTGPAARRVGRETPAAVMVRLFRCAAVLGVLAV
                     PAVLTGLAHDASGSGGYDYAAAWNALYDGSNAGRLSGLEVTLILAGAVLAVPLCIRKVA
                     VGPAGSWLAAAGLGAGAVALGATKFPDAVPEDWGRAGFETLMWMLHLLGGAVWLGGLAG
                     LALLALPGAVAPADRGVFWSASIRRFSAAAMSCVAAITLSGLFLYWEHVDGPTQLFTTM
                     YGRVLGVKILIFGVLLLLGVFNQFWLHPRVDALRAAGDDRPLHRILVRRFPAVVGIEVV
                     LGAAVLFVAPFLHGSARNQAFQANAAGATGSLADLPKIAPKAVHASTWFWGTTETIVVI
                     AFMVAGYWFSGVLARRRAAVAPALTTG*"
     CDS             complement(10498..12245)
                     /protein_domains="PF01301"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750766"
                     /pseudo=False
                     /translation="MPQLRIEPDGFRLDGDPFRIISGGLHYFRVHPAQWADRLHKARLM
                     GLNTIDTYIPWNLHQPERGRLQLDGPVDLPRFLGLAAQEGLHVLLRPGPYICAEWEGGG
                     LPSWLLAEPGIELRSNDPRYMAAVEAYFDALLPAVRPFLATNGGPVIAVQVENEYGAFG
                     DDTSHMRRIASLLTAGGVDVPLFTCDQPADLARGSLPGALAAVNFGSRAAAGVAALREQ
                     QPEGPLMVAEFWNGWFDRWGGLHVLRDAADAAAQLDAVLGAGASVNLYMFHGGTNFGFT
                     NGANDKHTYRPVVTSYDYDAPLDEAGDPTAKFDAFREVIARHAPVPDEPVPLPSKKLSI
                     LGIALDRSAPLLGSAPLLGEAVTAARPRTMEELGQDFGFVLYGTQAPEAGPAHLRVDDV
                     HDRAQVFIDGQPVGVLERESHHRALTFTVPRPGARLEVLVENQGRINYGRGIHDRKGLL
                     GEVHLNGRAPGNWTSRPLRLTSPEALDFSPTAAPPVGPAFYRGLFDVETPADSYLDLAG
                     WTKGNAWVNGFPLGRYWSRGPQRSLYVPAPIIRAGSNEIVVLELHATVRPAVALRDTPD
                     LGPEEE*"
     CDS             complement(12375..13453)
                     /protein_domains="PF13377"
                     /protein_domains="PF00356"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750767"
                     /pseudo=False
                     /translation="VTDSETADQAAGSPKGGGRAPAGRRRSVSMTDVAKLAGVSAQTVS
                     RVSNGSPGVVETTRAQVLAAMKELGYRPNSAARALKSGRFHTLGVILFNISTTGNTRTL
                     EAIATSAAQEGYAITLLPVAVPTQDSVRGAFTRMGELAVDGVIILMEAHLLDASTVTLP
                     PRTHVVVADSNAGDRYRVVDTDQIGGARAAVRHLLELGHDTVWHVAGPADSYSAERRVD
                     AWRTALRSRRREVPEPLRGDWTADSGYRAGLRLAQEPGCTAVFVANDQMALGVLRALHE
                     QGRTVPGEVSVVGFDDLPEAASFLPPLTTIHQDFSEVGRRCVEELLAQIRSDEAGTGTT
                     LVPTRLVARASTAPPPDTE*"
     CDS             complement(13607..14955)
                     /protein_domains="PF01547"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750768"
                     /pseudo=False
                     /translation="MRNPTLSRCVRAVAVLCAASFGLAACGSSGGSGSGSGGDKTSASE
                     VRSALAKGGSITVWAWEPTLKQVVADFRKKYPKVHVNLVNAGTGNDQYTALQNAVQAGK
                     GVPDVAQIEYYALGQFALSKSLTDLSGYGAKSLKKTYSTGPWNSVNINGGVYALPMDSG
                     PMALFYNKKVFDKYKLPVPTTWEQYLDDARKLHKADPKAYITSDTGDAGMTTSLIWQAG
                     GKPYKVNGTDVSVDFATDPGTAAYTKVWQQLISEHLVSPISGWSDQWYKGLGDGTIATL
                     ATGAWMPANFASGVKDASGDWRVAPLPQWHSGSRASAENGGSSLAVMKAGTKKDLAYAF
                     VQYADQGAGVRARIKGGAFPATTADLNSPSFQNEAFAYFGGQQANKIFAQSAKNVLPGW
                     SYLPYQVYANSVFNDSVGKAYTSGTPLASALKTWQDKSIAYGKEQGFQVK*"
     CDS             complement(14987..15927)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750769"
                     /pseudo=False
                     /translation="VATDTTTTERPQRPRSAVRPLRRTPRRSGYSADRPRRSILLTVLT
                     ALMVVYTLIPLAWLFINATKTQPKLLDSFGLWFSGHFALWDNVHRTIVHDHHIFLRWLL
                     NTLLYVVAGAGGATCLAVLGGYGLAKFAFPGRRAVFAVVIGAVAVPGAALAVPTFLMFS
                     KLGLTDTPWAVIVPSLISPFGLYLMWVFAAEAIPDELLEAARVDGSGELRTFFRIALPL
                     LAPGIVTVLLFTVVATWNNYFLPLIMIKNPHWYPLTIGLNSWNQQAATAGGRPVFNLVI
                     TGSLLTIIPLVAAFLLLQRYWQSGLAAGSVKE*"
     CDS             complement(15932..16866)
                     /protein_domains="PF00528"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_7750770"
                     /pseudo=False
                     /translation="MATGAPAAGGRGAVSARSRPRGPGRSRRWIGWGFVAPFAVVFALV
                     FLAPIGYSIYLSLYRDQLIGGNHFVGLDNYLQALHDHEFWSGLGRVGLFLVVQVPVMLG
                     IALLAALALDSGRLYGRNFFRISIFLPYAVPAVVATLMWGFMYGKRFGLVASINEHLHT
                     SIPDPLSPHWVLVSIGNVVTWEFVGYNMLIFYAALRVIPSALYEAAEIDGAGQWRIIRS
                     IKIPAIRGALVIATVFSIIGSFQLFNEPSILKSLAPNAITTYFTPNLYTYSLSFGGRQH
                     NYAATVAILMGIVTMIVAYAVQLRGMRKEK*"
ORIGIN
        1 tcagacgtcg agatcgacca cgacaggggc gtggtccgac gcgcccttgc ccttgcgctc
       61 ctcgcggtcg acgtagctgt ccttgaccgc cgccccgaac gggccgttgc cgtacacgag
      121 gtcgatgcgc atgccgcggt tcttggggaa gccgagctgg cggtagtccc agtacgtgaa
      181 ggggtggtcg tacttgagcg gcctcggcac cacgtcccgc aggccctcct cccgcagcgc
      241 cgcgagcgcg tcccgctcgt ccgcggtgac gtgcgtggct ccctcgaacg ccgagcggtc
      301 ccacacgtcc gcgtcggtgg gcgcgatgtt gaagtcgccg agcacggcga acggccgctc
      361 gcccgccgcg tcctgggtga tcgtgcccct gagcgcgtcc agccagcgga gcttgtaggc
      421 gtagtgggcg tggccgacct cccggccgtt gggcacgtac accgaccaga cacgcacggg
      481 gccgcacgtc gccgcgacgg cccgcggctc ctcgacgccc tcgtactccg ggccgccggg
      541 cagcccgcgc acgacgtcgt cgaggccggc gcgggagagc accgccacgc cgttccaccg
      601 cccggtcgcg tggaccgcgg actcgtagcc gatctcacgc agcgcctgct cggggaactg
      661 ctcctgggtg gtcttggcct cctggaggca cagcacgtcc gtgccactgc tctccagcca
      721 ggcgagcagc cggggcaggc gggccgtgat cgagttgacg ttccacgtgg cgatgcgcat
      781 gcggaccagc ctataggcgg ggtacgacag tcagggccga gtcggtcaca gctccacact
      841 gtcgccgggc gcgagcctgc cgtgctccgc gcccgcgagc ccgccgagca tccggtcgta
      901 catgggcctg gcgacctcgg acagcagcgc gtcgtgcacg tcgtaggcgc ggcgcggctc
      961 cacctcgcgc aggtagtcga cgatctcggc gatcttgttc cagggcgcca tcacgggcag
     1021 catcagcgtg tcgacggggc gctccggcac ggtcagggcg tcgcccgggt ggaagaccga
     1081 cccgtcgacc aggtagccgg agttggcgat ccgcgggatg tcggggtgga tcaccgcgtg
     1141 cagctcgccg tgcacctcga cgtcgaaccc ggccgcggtg aaggtgtcgc cgtggccgac
     1201 cgtgtggacg cggccgggga aggcggccgc gaccttgtcc gtgacgctgc ggggcgccca
     1261 cagctcggcc gccgggttgt cgccgagccc ggcgcgcagc cggtcctcgt cgaagtggtc
     1321 cgggtgctcg tgggtgacga ggacggcgtc ggcgcccacc gccgcgtcct gctcgctgta
     1381 gccgcccggg tcgatgacga gcgtgcgccc gtccttctcc agccgtacgc acgcgtgccc
     1441 gcgcttggtg aacctcaccg tcgaccgcct tcgctcgggg atgcggggtg cgggggtggc
     1501 ccgcacctcc atcctgctac tcctgcggcc gggtctcctc ccggatcact tcggcggcga
     1561 ccttgaaggc ggcgttcgcc gccggcacac cgcagtagat cgcggtctgc agcagcacct
     1621 ccttgatctc ggccgggctg aggccgttgc gcagggcggc cgtggtgtgg aacctcagct
     1681 cgtccaggtg gccgcccgcg acgagggcgg tgagcgtgat cacgctgcgc gtgcgccggt
     1741 cgaggccgtc gcgggtccag atctctcccc acgcgtagcg ggtgatcagc tgctggaagt
     1801 cctccgtgaa ggcgtcggcg gacgcggtcg cgcggtccac gtgctcgtcg ccgagcacct
     1861 cgcggcgtac ccgcatgccg gcgtcgtgga ggtcggggcg gccctgcggc tcggcgggct
     1921 ccggctgctc ctcctgctcg tcctgcgcct gcgcctgcgc ctgcgtctgc gcctgcgtct
     1981 gcgggggctc ctcggactcg gcgggtccct cggccccggg cacggaggcc gcgggctcgg
     2041 gcctgcggtc gggcgggagc gtgatgccgg tggtcgtctc ggacgggttg taccaggccg
     2101 tcgagaagtg gtcggtcagc aggtcggtga cggccgcggg ctgctcgacc ggcgcgaggt
     2161 gggaggcgcc gggaaccagc gcgaggcgcg cgtccggtat gcccgcgacc agcgtgcggg
     2221 cctcggcggg ccctgtgacc tggtcctcgg ctccgacgag cacgagcgtc ggcacggcga
     2281 tgctgccgag ctcggcgcgg atgtcgaagg cggcgagcgc ctcgcacgcc gcgatgtagc
     2341 aggcgggctc cgtggtgcgg accatctgca cggcccactc gacgatcgcg ggctgcgccg
     2401 cggcgaaccc gggggtgaac cagcgctccg gcgcgctgcg cgccatcggt tcgagcccgt
     2461 tggcgcggac gatgacgcca cgctggcgga actcgtcggc ggtgccgaac cggggcgagg
     2521 ccgcgatcag ggcgagcgag gccacccgct cgccgtggcg cagcgccagt tcggcgccga
     2581 cagccgcgcc gagcgcgcag cccgcgtagc cgaagcgctg gacgccgagg ctgtcgagcg
     2641 tgtcgagcag gcgctgcgcc agctcgggca ccgcggcggt ggcctcggcg ggagcgccgc
     2701 cgtggcccgg caggtcgaag cgcaccacgc accactgttt ggccagctcg ggtacctggc
     2761 ggtcccacat gtgccatgtc gtgccgaggg agggtccgag gaccagggcc ggggcgtctt
     2821 ccggcccgtc aacgcggtac tgcagggtct gggtcgatat ctcactcacg ggatcaatcc
     2881 tttatctgtc acgatctgtc acgctccccc tcgcaagacc gccccacgcc ttcgccaccg
     2941 gaagcaagtc caccacgtcc ggctttacgt accacttctc ggtcgtcttc acgtctgtgt
     3001 gcccggcccg catggcgagc aggtgatccg gcacgccgtt gccggccgga tacgtcaagc
     3061 acgacgcccg agcatcgtac agacgaaccc tgcgaaggcc gttgtcgtat ccctcgcccg
     3121 ccgccggacg ctccttcgcc tgcatggcgc gggattcccg cacagctgga tcatgagctg
     3181 cgggaggcaa cctcggtcag cacctgtcgg cgtttcggcc atctcctgcc ccgagccgtt
     3241 ccaagccgca gcaaggatcc cggctacgca aggtcccctc acgcgggaaa tggcgggctt
     3301 cgcggcgcga ccgaatgaca tgtgttcgaa atcgtgggtc gggtcgttga gcctcatgac
     3361 tctgccgcag cgaccgtctc agggggaacg atgacctcgg ccatcacaca ggaccagccg
     3421 gcacaaccac cgaagggcac ctcgcgggac gacgagccgg aggaggccgg tgttcgagac
     3481 gaggagtacc tctaccgcga cgcgtcacgg ctgcaggccg gatccctcct gaccacccgc
     3541 acgatggcac ggcggctgcc cgcgctcgtg ctgcgatccg tacggatggc ctggcgggtg
     3601 gaccgcggca cgaccgtcgg gctgctggtg tgccagacag ccaccggtgt gttcgccgcg
     3661 ctcggcctcc tggctgtcac cggcaccctc acctcgctga tctcctcggg cgccgtcgtc
     3721 cagcggctgt gggacgccgc gccgcagttg gcggttgtcg ccgcggccac cggactgcgc
     3781 gcgctgctgg gcatcgccgt ggtctggctg accgggcgtc tgcgccccgt actcgcccgc
     3841 gcggcggaag tgacgatggt ggaggccacg ctcggcgcgg aaccggccgc caacaacaag
     3901 cccggctaca acgacgccta cgacatcgcc gaccgcggcg cccaggtcac ccccgacctc
     3961 gtggaggagg cccaggacgt actcgccgcg accgcgaccc tcacagccgg cgcaaccgtc
     4021 ttgaccgtcc tgcacccgct ccttctgccg tcctgaacga aggccggatc gtgcaggagg
     4081 gcacctatgc ccaactcacc cagcaaacgg ggctcttcca gtccttttgg aagttgcagc
     4141 gacgaatgag cggcgaggcc gcctgacctg accccgacgg tggtggcccg gcacccgacg
     4201 tggctgcggc accggggagc cggctgccca ccttctgccg cctcgccgcc caccaggaac
     4261 cgggacccga tgagtcggcg cactgtgcga cgcctgagca gggcgggccg gccccccgtc
     4321 atctgagccg ccaacgcccg ccgttccccc gaagcacggc tttgaccagt gggaatagcg
     4381 aagggctgct ggagcactaa ccgaacaatg gcttgccgat gtaggagccc gccttcggcg
     4441 ccggtggcac ggcgaagacc gcggaaccta tgtgggagat gtattcgttc agcctgtccg
     4501 atgcgccgag ccgcttctgg agcctgacga agtgatcagg gtcgttcatg taggcgatga
     4561 acaggagtcc ggcgtcgagt tgtccgtact ggttgatccc gtcggtgtag ttgtaggacc
     4621 ggcggaggat cttgaggccc ccgttgttct cgtgtgcggc cagtgctatg tgcgacgtcg
     4681 ggtcgatcgc tttgccgccg cccggtagcg tcgcgtggaa gtccggtgtg gtgtgctcgc
     4741 gtccgcccga cagcggggca cccgccgtct tggtgcggcc gaagacccgt tgctggtcgc
     4801 tgatcgggtc ggcgtcccag atctcgatgt tcatctgtat cttgcgcacg acctggtaac
     4861 tgccgcctgc catccacccc tcgtcgctgc ccgcccacac ccagcgccgg tagtcgtcct
     4921 cggtccggat gttgcgtgtg ccgtccttga agccgagcag gttgcgggga gtggcctgat
     4981 cggggccggc cgacgcccgg ccgaacccga gcaccgtcca ccgcaccgcc gcgttgccgc
     5041 gtgcgatgcg ggtgaggtcg cggatcgcgt ggtaggccac ctgtggatcg tcggcgcatg
     5101 cctggagcga caggtcacct ccggtgaggg cggcgtcaag gcggtcgctg ggcagcgcgg
     5161 gcagcgcggg cagcgcggcg agcctcgcgg ggcgtttgtc cgcgaggccg aagcgttcgt
     5221 cgaagatgcc gggcccgagg ccgagcgtga cggtcagcga ggcaggtccg aggtcgaggg
     5281 cctccccggt gtccaccccg gctcccgagc cgtgggccgg ctcgaccagg ccgacggtgt
     5341 tgcccttctg cagttgcgcg atcgaggccg accaccgggc cagcagcacc tggagatcgg
     5401 cggcacttga cgatgtgacg tcgaaggccg cgaggacacc gtagcgttgc ggtgcggtcc
     5461 ggatgccggc ctgcggggag gcgtcggcgg tcgcgtagaa cggatggcgt ccggtcaggt
     5521 cgatcagttc gcccgatggc cgggtgggtg tggcggccgg gccgttcgcg aacagggccc
     5581 cggcgcccgc gtagacgccg gctcccgctc ctgcggcggc cagaccgccg ccgaagaggg
     5641 ctcgtcgcga cacgccgggg cgggcggctc gcgaaccgtc cgccccggtg ccgtcatgct
     5701 gtgcgctcac tttgcggtcg cgactttctg ggcgaggtgg gacagcgggt cctgcaaggc
     5761 ctgcaccgac tgcgagatct tcttggcgtt cgcggtcttg gtggcgccgt cccagcgctg
     5821 gtatccgccg agggagccgg cgtcgcggag cttgcccatc acggtgtcga cgccggagaa
     5881 gcgctgctgg atcgtcttgg tgagggccgg gtcgatcttg gtcagcccgg gctggaggta
     5941 ggcgaacgcc tgccgggcac cttcgacgtt ggcggagagg tccgcgaggt cgatgtggct
     6001 gaacgcctcc tcctcaccgg tgatcttgtt cgactgcact tcctccagca gcccggccgc
     6061 gccgttggcc aggtcctccg gcttgaactg aagcttcggg gccagctttt cgagcgtggt
     6121 cacattggtc accagctcgg cggcgagttt cttcgtcgac ggggtgatgg ctcccccgtg
     6181 ccacaggtcg cgctcgatgg catggaaccc gtgccagccg acggcctggt cgaggttgga
     6241 ggcgcgcatg tcgatgagat agtcgaggtt gcccgcgttg tcggtcggct tgaacccggg
     6301 cttcacgaag cctgccacat cggattcgat cttctcgtag aactgccggg tacccgcgta
     6361 gtcggtcttg gccttcttca ggttcccggc gtctatgtcg gcctgcaggg tcttcgagcc
     6421 cttcagcaga tcgttcagcc gggccgtgac gtagccgctg taacccttcg cgccctgggc
     6481 gagcagcgtc gcggtgctgc cactggcgac cggggccggc ttgcctgtga cagtgaaatc
     6541 ggtgagctcc ttggccgcac cagggcagta gagctggtac ttcccaccac cgagggtggc
     6601 cgtgaacgac acgggggcca ggcccggtgc gaggttctcc ttctcgccga cgatgcgctg
     6661 ctgctgcagc aactcgaact cgatgatccc ggtggccgac tcgttcttga ccgtgaaggt
     6721 gaccgggccg gccttcgccg tcgtcgcgct cgcctcacag gtgtccccgg agccgccgct
     6781 cttcagcgtc acggtcaccg ccgaggaacc gccggccttc gccccgctct tggcggtgcc
     6841 tgccgacccg gacgcggtgg cctgcccgga gtcgttcgac gagcagctca cgagcgtgag
     6901 cacggtgagc acaccgaccg ctccgatcgc ggtgcgtcgg cgggttggtc ggggaaggcg
     6961 gtcagcggac aacatcgttg gtgctccttc gaggttcttg cgacgcttcg tcgtcggcgt
     7021 tcgtggaaag ggaggggttg ccggccccgt cggccggctc gggcgagtcc gccggatcac
     7081 gggtcagacc gcggcgggtg cgccggcccg tcagcgccag cccgacggcc gcggcgccca
     7141 gggccgccgg cagccacagg cgccacaacg tgcgctcgtg tgcggtgagt tcgccgtcgg
     7201 cgaccgcttt gccggtcgcg gtgaccgccg cactggggac cgaccagtag ggctcggtca
     7261 tcgtcagggt gcgcggcctg cccaggccgc cgcccgtcag cgtcagtgtg gtccggtcga
     7321 cgcgtcgcgc gtcgaggatg ccgtgatgag tgagccagag ggtgctcgtc gtggtggtcg
     7381 tccactgcgc gtggtacggg ccggggttct gcgtgttcga gatcccgacc ggcacgcggc
     7441 cgaagagcgc cgcgagttcg tcgatggtga gtgtcgacgg ccgacccgag ctgctcgcac
     7501 gggcgtgttc tgtccactgc tcggccctca cccccgcgtg gtccgcggaa gtccgggccg
     7561 cgccggtgaa tctgacggtc tgcgtggtcc caccgccatg gacgagcagg gacgccgagt
     7621 ctccgcgaac cgtgaccgac gccgtacccg ccgaggaggc cggggggtgg tgcggatcgc
     7681 ccttgcccgc ggtgagcgcg accgtggtgg ggaccgaggg cttcccgtcc ggcactgcca
     7741 gcggaagtac caccgctgac agtgcggcgg ccgcggcgat ggagaacttg acggtgggca
     7801 cccgggcggg ggccgcgcgc caacggcgcg gccacagtgt gacagccagt accggcacga
     7861 ggtaacacag ccacgccagc gcctcgatca tgcgcggatc ggcggggatt ccgagcacac
     7921 cggtgatcag tgcggagcgg atcgagccga tcggcgagag ccacgagagg tcgaccgtgt
     7981 gctgctgccc gatgtcgatc cagcccgcgc cccgtgcggt gcggaacgcg gtcagcagca
     8041 gcccggcggc gacgaacacc aggaagacac cggagatggt gaagaacctg gacaggttca
     8101 gccgcgcacc gccgaagtag aggatgcagc cgaccacaca cgccacgacg atgccgatcg
     8161 ccgcgccgag cgcggcggcg cctgcactgg tcgaggcgtg cagggtggcc agcaggaaca
     8221 ccgcggtttc gaagccctcc ttcaccaccg cgaggaacgc catcccggcc agtgcccagc
     8281 cggttcccct ggacaccgcc gcaccggccg acccttcgag ttcggcgcgc agtccgcggg
     8341 cgttcttgcc catccagacg atcatccccg tcacgaagac caccgcgacc aggccgatga
     8401 ccgactccag gccctcctgc tttgcctggg gcagcgactg ctcaagcgcc tgaagggcga
     8461 caccgacgcc gacggacacc agtaccgcga ggccgacacc gcaccacatc ggccggcggg
     8521 gtacaccgtt gcgcttcagg aacgcggcga tgatgctgac gatcaggacg gcttcgaggc
     8581 cctcacgcag gccgatcacg aaagtggtga gcatcagttg ccgcctcggc gaagggtttt
     8641 cgcgggcggg tccgaccgct tccgaacggt gttgcggtgc acaaccatgg cgacagcctg
     8701 cttcccgtcg tgcctgatgg ccctgtgaac gacgtaggtg aggaaggata gccttaccta
     8761 atcaatagcg gaacagccgg gtgccggccg gccggatcag ccggtggtca gggcgggtgc
     8821 cacggcggcg cgacggcggg ccagcactcc agagaaccag tagccggcga ccatgaaggc
     8881 gatcacgacg atcgtctcgg tcgtgcccca gaaccaggtg gacgcgtgaa ccgccttggg
     8941 cgcgatcttc ggcaggtcgg cgagcgaacc ggtggcaccc gcggcgttcg cctggaacgc
     9001 ctggttgcgg gccgagccat gcaggaaggg ggcgacgaag agcacggccg cgccgagcac
     9061 cacctcgatg ccgaccacgg ccgggaaccg gcggacgagg atcctgtgca gcggccggtc
     9121 gtcccccgcc gcacgcaggg cgtcgacccg cgggtgcagc cagaactggt tgaagacccc
     9181 gagcagcagc agaacaccga agatgaggat cttcacaccg agcacccgcc cgtacatcgt
     9241 cgtgaacagc tgcgtggggc cgtccacatg ctcccagtag aggaagagcc cggacagtgt
     9301 gatcgcggcg acgcagctca tggcggcggc ggagaagcgc cgtatcgatg ccgaccagaa
     9361 caccccgcgg tccgcgggcg cgaccgcacc ggggagcgcg agcagggcga ggccggccag
     9421 gccgccgagc catacggcgc caccgaggag gtgcagcatc cacatcaggg tctcgaagcc
     9481 ggcacggccc cagtcctcgg gcacggcgtc cgggaacttg gtggcaccca gcgcgaccgc
     9541 acccgcgccg aggccggccg cggccagcca cgacccggcc gggccgactg ccaccttgcg
     9601 gatgcagagc gggaccgcca gcacggcacc ggccaggatc agcgtcactt cgaggccgga
     9661 cagccggcct gcgttgctgc cgtcgtagag cgcgttccag gccgcagcgt agtcgtaccc
     9721 gccgcttccc gacgcgtcat gggcaagacc ggtcagcacg gcgggtacgg cgagaacgcc
     9781 gagcacggca gcgcatctga acagcctcac catcaccgcg gccggcgtct cccgcccgac
     9841 gcgacgcgcc gcgggacccg tgacgacgag cgcgagcgcg gcgaggccga cgaagcccat
     9901 gagcgtgatc caggtcgccc aggcgacggc actgtccacg aacggaccga ggggagttga
     9961 tggcgccgac gccacgagaa ccgactgatg gtggggcaaa tcctcaacac gaagcacgat
    10021 cgaccgcccg tctcgttgaa tgtcgtaccg tcgtcgagtt aggttaggca tacctaacta
    10081 tctaggtcaa caaggggtgg ccgcccgccg gtagctggtt cgcagcgtcg ccggcaacgg
    10141 acgcgacggg cccgatgatc tgcccggccc ggtggtcggc caacggccgc cgcctgggcg
    10201 caggttcgta cgcgccggac cgttttcttg tgtcttgtga cgaacggagt ggagcagacc
    10261 gagcgccgcc cacccgcaac cattcgcttt acctggactg tgtcgaccgt cctggaaggg
    10321 ttctgcgacg tgcgccacgt cgtgccgagg gaaggcccga ggaccagggc cagggcgtct
    10381 tccggccctg caacgcggca ggcccggctc cgcggtcctc gccgtcgcga catgtctgcc
    10441 gcgacggctc tcccgtgtca catcgaggcg aacgtgcccg acgcggtgac gcgctctcac
    10501 tcctcctcgg ggcccagatc cggtgtgtcg cgcagggcca ccgcgggccg gacggtggcg
    10561 tggagttcca gcaccacgat ctcgttggaa cccgcacgta tgatcggcgc cggaacgtag
    10621 agggagcgct gcgggccccg ggaccaataa cggccgagag ggaagccgtt gacccaggcg
    10681 ttgcccttgg tccatcccgc gagatccagg taggagtcgg caggggtctc gacgtcgaac
    10741 aggccacggt agaaggccgg gccgaccggc ggggcagccg tgggtgagaa gtccagggcc
    10801 tccggggatg tcagccggag cgggcggctg gtccagttgc cgggcgcccg gccattgagg
    10861 tggacctcgc ccaagaggcc cttgcgatcg tggatcccgc gaccgtagtt gatccttccc
    10921 tggttctcca ccagcacctc caaccgggcg ccggggcgcg gcacggtgaa ggtgagcgcc
    10981 ctgtggtggc tttcccgttc gaggacgccg accggctgcc cgtcgatgaa gacctgggca
    11041 cggtcatgca cgtcgtcgac gcgcaggtgg gcgggcccgg cctcgggcgc ctgtgtcccg
    11101 tagagcacga agccgaagtc ctggccgagt tcctccatgg tcctggggcg ggcagcggtg
    11161 accgcctcgc cgagcagggg agcgctgccg agcaggggcg cgctgcggtc cagggcaatg
    11221 ccgaggatgc tgagcttttt cgacggcagc ggcaccggct cgtcgggcac gggggcgtgg
    11281 cgggcgatga cctctcggaa ggcgtcgaac ttggccgtgg ggtcgcctgc ctcgtccagg
    11341 ggcgcgtcgt aatcgtagga ggtgacgacg gggcggtagg tgtgcttgtc gttggcgccg
    11401 ttggtgaagc cgaagttggt cccaccgtgg aacatgtaga ggttgacgct ggcacccgcg
    11461 cccagaacgg catcgagttg cgccgcggcg tccgcggcgt cgcgcaggac gtgcagcccg
    11521 ccccagcggt cgaaccagcc gttccagaat tcggccacca tcagcggccc ctcgggctgc
    11581 tgttcgcgca gggccgcgac gccggcggcg gctcggctgc cgaagttgac ggccgcgagc
    11641 gctccgggca ggctgccgcg ggccaggtcg gccggctggt cgcaggtgaa caaggggacg
    11701 tcgacgccgc ctgcggtgag caggctcgct atacggcgca tgtggctggt gtcgtcgccg
    11761 aaggctccgt attcgttttc cacctggacg gcgatcaccg ggccgccgtt ggtggccagg
    11821 aacggcctca cggcgggcag aagggcgtcg aagtacgcct cgacggcggc catgtagcgc
    11881 gggtcgttgc tgcgcaactc gatgcccggc tccgccagca gccaggaggg aagcccgccg
    11941 ccttcccatt cggcgcagat gtacggcccc gggcgcagca gcacgtgcag tccctcctgg
    12001 gcggcgaggc cgaggaagcg gggcaggtcg accgggccgt cgagttggag ccggcctcgc
    12061 tcgggctggt gcaggttcca cggtatgtag gtgtcgatgg tgttcaggcc catgagccgg
    12121 gccttgtgca gccggtcggc ccactgcgcg gggtggacgc ggaagtagtg cagaccgccg
    12181 gagatgatgc ggaaggggtc tccgtcgagc cggaaaccgt cgggttcgat ccgcagctgg
    12241 ggcatggggt cctgctcctt ccgggagcgt cgtcgaaaca gggatggttg cgcaatcatt
    12301 ctcatggccg ttgcacaggg ccagggtggc gtcaccttcg cggccggggc cggccgttgc
    12361 ccggcccggg tcgtcactcg gtgtcggggg gcggtgcggt gctggcgcgg gcgacgagcc
    12421 gggtgggcac gagcgtcgtt ccggtccccg cctcgtcact gcgtatctgt gcgaggagtt
    12481 cttcgacgca gcgacgtccg acttcggaga agtcctggtg gatggtcgtc aacggcggca
    12541 ggaaggacgc ggcctccggg aggtcgtcga accccaccac gctgacctcc ccaggaaccg
    12601 tgcgtccttg ttcatgcagt gcgcgcagga cgccgagggc catctggtcg ttggcgacga
    12661 agacagcggt gcagcccggt tcctgggcga gccgcaggcc ggcacggtat ccggagtccg
    12721 cggtccagtc gccgcggaga ggttcgggga cctcccgccg cctggacctc agcgcggtgc
    12781 gccaggcgtc gacccggcgc tcggcggagt aggagtcggc cggtccggcg acgtgccaga
    12841 cagtgtcgtg cccgagttcc agcagatgcc ggacggcggc acgcgcgccg ccgatctggt
    12901 cggtgtcgac gacgcggtag cggtcgccgg cgttcgagtc cgcgacgacg acgtgtgtgc
    12961 gcggcggcag cgtgaccgtg gaggcgtcca gcaggtgggc ctccatgagg atgatgacgc
    13021 cgtccacggc aagctccccc atacgggtga aggcgccccg gacgctgtcc tgggtcggca
    13081 ccgcgactgg caggagggtg atggcgtatc cctcttgggc ggccgacgtg gcgatggcct
    13141 ccagcgtgcg cgtgttaccg gtggtggaga tgttgaacag gatgacgccg agagtgtgga
    13201 accggccgct cttcagagcc cgggcagcgg agttcggccg gtagccgagt tccttcatcg
    13261 cggccagtac ctgcgcccgg gtggtctcca ccacgccagg agaaccgttc gagacccgag
    13321 agacggtctg cgcggagact ccggcgagtt tggccacatc cgtcatcgag acgctgcggc
    13381 gtcgcccggc gggggctctt ccgccgcctt tgggcgaccc ggccgcctga tcggctgttt
    13441 cgctgtcggt cacttgcttt cctgcacctt cacccgctgg cccggggcct gacgatggcc
    13501 gatgtcacag tgtagggacg ctgccgcgga tggaccgtcg gtacggcccg cgccggtacg
    13561 tgcccgcctg gtgcggtggg ccgcatcggc cggaagcggc atccgtcact tcacctggaa
    13621 tccctgttcc ttgccgtagg cgatcgactt gtcctgccac gtcttcagtg ccgaggccag
    13681 cggtgtcccc gaggtgtacg ccttgccgac ggagtcgttg aacacggagt tggcgtagac
    13741 ctggtaaggc aggtaggacc agccgggcag cacgttcttg gcggactggg cgaagatctt
    13801 gttggcctgc tggccgccga agtacgcaaa cgcctcgttc tggaacgagg gagagttcag
    13861 gtccgcggtg gtcgcgggga aggcacctcc cttgatcctg gcccggacgc ctgcgccttg
    13921 gtcggcgtac tggacgaagg cataggcgag gtccttcttg gtgccggcct tcatcaccgc
    13981 gagcgagctg ccgccgttct ccgcgctggc ccgggagccg gagtgccact gcggcagcgg
    14041 tgccacccgc cagtcgccgg aggcgtcctt gacgccggag gcgaagttgg ccggcatcca
    14101 ggctccggtg gccagtgtgg cgatggtgcc gtctcccagc cccttgtacc actggtcgct
    14161 ccagccgctg atcggggaga ccaggtgctc ggagatgagc tgctgccaga ccttggtgta
    14221 tgcggcggtg ccggggtcgg tggcgaagtc gacggagacg tccgtgccgt tgaccttgta
    14281 cggcttgccg ccggcctgcc agatcaggct ggtggtcatg ccggcatcac cggtgtcgct
    14341 ggtgatgtac gccttcgggt cggccttgtg cagcttgcgt gcgtcgtcca ggtactgctc
    14401 ccaggtggtg ggcaccggca gcttgtactt gtcgaagacc ttcttgttgt agaacagcgc
    14461 catcgggccg gaatccatcg gcagggcgta gacaccgccg ttgatgttca ccgagttcca
    14521 cgggccggtc gagtacgtct tcttcaggct cttcgcgccg tagccgctca ggtcggtgag
    14581 ggacttcgac agcgcgaact ggccgagcgc gtagtactcg atctgcgcga cgtcggggac
    14641 gcccttaccg gcctggacgg cgttctggag tgcggtgtac tggtcgttgc cagtaccggc
    14701 gttgaccagg ttgacgtgca ccttggggta cttcttccgg aagtcggcga ccacctgctt
    14761 gagggtgggc tcccatgccc acacggtgat cgaaccgccc ttggccaagg ccgaccggac
    14821 ctccgaggcg gacgtcttgt caccgccgga tccggatccg gagcctccgg aggagccgca
    14881 ggcggccagg ccgaaggagg ccgcgcagag cacagccacg gcccggacac accgggagag
    14941 tgtcgggttt ctcatgagtc tcactccgtt gtgcgtgatg aggggtcact ccttgacgct
    15001 tccggccgcc aggcccgact gccagtagcg ctgcagcagc aggaaggccg cgacgagcgg
    15061 gatgatcgtc agcagggagc cggtgatcac caggttgaag acgggccggc cgccggcggt
    15121 cgcggcctgc tggttccagg agttcagccc gatggtgagc gggtaccagt gcgggttctt
    15181 gatcatgatc agtggcagga agtagttgtt ccacgtggcg accacggtga acagcagcac
    15241 ggtgacgatg ccgggggcca gcagcggcaa ggcgatccgg aagaaggtgc gcagttcccc
    15301 ggagccgtcc acacgggcgg cctccagcag ttcgtcgggg atcgcctcgg cggcgaacac
    15361 ccacatcagg tagaggccga acggggagat cagcgagggg acgatgaccg cccaaggggt
    15421 gtcggtcagg ccgagcttgc tgaacatgag gaacgtgggc actgccagcg ccgcgccggg
    15481 caccgcgacg gcgccgatca cgacggcgaa caccgcacgc ctgcccggga atgcgaactt
    15541 cgccagcccg tagccgccca ggaccgccag gcacgtcgct ccgccggcgc cggccaccac
    15601 gtacagcagt gtgttgagca gccagcgcag gaagatgtgg tggtcgtgga cgatggtccg
    15661 gtggacgttg tcccacagtg cgaagtggcc gctgaaccac aggccgaagg agtcgagcag
    15721 cttcggctgt gtcttggtgg cgttgatgaa caaccacgcc agtgggatca gcgtgtacac
    15781 caccatcagc gcggtgagca cagtcaggag gatgctgcgg cgcggccggt cggcggagta
    15841 gccgctccgg cgcggtgtgc ggcgcagggg gcgcaccgcg gaccggggcc gctgggggcg
    15901 ttccgtcgtg gtggtgtcgg tggccacggc tcacttctcc ttgcgcatac cgcgcagctg
    15961 gacggcgtag gcgacgatca tggtgacgat gcccatgagg atggcgaccg tggcggcgta
    16021 gttgtgctgc cggccaccga aggacaggga ataggtgtag aggttcgggg tgaagtaagt
    16081 ggtgatcgcg ttcggtgcga ggctcttcag gatgctgggt tcgttgaaca gctggaagct
    16141 gccgatgatg gagaacacgg tggcgatcac cagggcgccg cggatcgccg ggatcttgat
    16201 cgagcggatg atccgccact gcccggcgcc gtcgatctcc gccgcctcgt acagcgcgga
    16261 ggggatcacg cgcagcgcgg cgtagaagat gagcatgttg tagccgacga actcccaggt
    16321 gacgacgttg ccgatgctca ccagcaccca gtgcgggctc agcgggtccg ggatcgaggt
    16381 gtgcaggtgc tcgttgatgc tcgccaccag gccgaaccgc ttgccgtaca tgaagcccca
    16441 catgagcgtg gcgaccacgg ccggcaccgc gtagggcaga aagatcgaga tacggaagaa
    16501 gttgcgcccg tacagcctcc cgctgtccag cgccagtgcc gcgagcagag cgatcccgag
    16561 catgaccggc acctggacca ccaggaacag tccgacgcgg ccaaggcccg accagaactc
    16621 atggtcgtgc agcgcctgca aatagttgtc aagaccgacg aagtggttgc cgccgatcaa
    16681 ctggtcccgg tacagactca ggtagatcga gtagccgatc ggcgcgagga agaccagcgc
    16741 gaagacgacg gcgaacgggg cgacgaaccc ccagccgatc cagcgcctgc tccgcccggg
    16801 tcccctcggg cgggaacggg cggaaacggc tcccctccct cctgcggcgg gtgcgccagt
    16861 ggccat
//
