LOCUS       reptomyces_RBGC_623134 15618 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_623134
VERSION     Streptomyces_RBGC_623134
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_001553475.1
  ORGANISM  GCF_001553475.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1788
                     /protein_domains="PF00750"
                     /protein_domains="PF05746"
                     /protein_domains="PF03485"
                     /protein_domains="TIGR00456"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415173"
                     /pseudo=False
                     /translation="MASVPSLAATVHQRVADALSAALPEAGSADPLLRRSDRADFQANG
                     MLALAKKLKGNPRELASKVVAHLPVAATSADPDPVIADIEVSGPGFLNISIADSAITAT
                     LAARAADERLGVPYAEAPGTTVIDYAQPNVAKEMHVGHLRSAVIGDAVVRILEFAGEKV
                     IRRHHIGDWGTQFGMLIQYLIEHPHELDHKDAASGQEAMSNLNRLYKAARALFDSDPEF
                     KERSRRRVVDLQAGDEETIALWRKFVDESKIYFYSVFDKLDIEIRDPDVVGESGYNDML
                     AETCRLLEESGVAVRSEGALCVFFDDIKGPEGNPVPLIVQKSDGGFGYAATDLSAIRDR
                     VRNLKADTLLYVVDARQSLHFKMVFETARRIGWLGDRVHAVQLAFGTVLGKDGKPFKTR
                     EGETVRLEDLLDEATERAAAVVREKSEKLGLTEEEILERGAQVGIGAVKYADLSTSASR
                     DYKFDLDQMVSLNGDTSVYLQYAYARIQSILRRAEEGQRPRAHPELPLAPAERALGLHL
                     DQFGETLRDVAAGFEPHKLAGYLYQLASLYTTFYDQCPVLKAEGGPAQVENRLFLCDIT
                     ARTLRQGMTLLGIRTPERL*"
     CDS             complement(1970..3471)
                     /protein_domains="PF00561"
                     /protein_domains="PF08386"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415174"
                     /pseudo=False
                     /translation="MRLTTGRTAVLALATAATASLLGSTVSAADATPRRQTGPTATALG
                     WGACEGTGLDPRQECATLKVPLDYRDPGGKRISLAVSRVPSERPRARRGTLLLIPGGPG
                     SPGLDRPTTLGKRLPRSVRDAYDIVSFDPRGLGRSTHAGCDLAPADLSLLASRPWPAPG
                     GDITENVTTGRRIADTCARNGGDLLRTLSTVNEARDIDSIRRALGERKLSAWGVSYGTY
                     VGSVYAQMFPEHTDRWVLDSNDDPDPERVERGWLANYAVGVEDTFPDFAAWASAPGSPV
                     RLAGTPDGVRRRVLALAARLDANPLPWPGANPPELNGNVLRQSMLSALYSPDTFEGLAR
                     LIVDADAGKVPDAAPADPTQDIAAVSLATICNDVEWPTSLTAYARDVAASRTSHPLTAG
                     MPVNVTTCAFWHDKPRDKPVRITGQGPSNVLLVQNTRDVATPYRGALELRRAYRDRARM
                     VSVDAMGHGAAYRVNHGSDCADRRVTDFLLTGELPKRDLRCP*"
     CDS             3692..4302
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415175"
                     /pseudo=False
                     /translation="MRRWRTALAAMALAGGALAATAGTAGAVVPAAAGARAGTTGAGAT
                     ACETGWGSGEKTARPAGHTPLTNVRTGRHACFDRIVFDVRGATAAGPIGYRVGYVNALH
                     QDGSGEEIPVGGGAILEIRVAAPSYDPGSGAESYPGRARKPLPGVDLTGYQTFRDTRFG
                     ASFEGDTQVGLGVRARLPFRVLQTDGHVVVDVAHSWTALR*"
     CDS             complement(4390..5348)
                     /protein_domains="PF00768"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415176"
                     /pseudo=False
                     /translation="VRLIRERPCYVVAGQGHLEILTLKTGMKGLCRVSAVTVTAGAVLT
                     AGAFTASAQAATTATPTIVAKGGFVMNNGTGKSLFTKAADTRRSTGSTTKIMTARVVLA
                     QPNLNLDAKVTVQKAYSDYIVDNNWASSAKLIVGDKVTVRQLLYGLMLPSGCDAAYALA
                     DKFGTGSTRAARVKSFIGKMNSTAKSLGLTNTHFDSFDGIGHGANYSTPRDLTKLASSA
                     MKYSTFRTVVKTKSTKQKVTTKNGGYRYMSWTNTNNLLGSYSGTIGVKTGSGPEAKYCL
                     VFAATRNGKTVIGTVLASSSVDNRTADAKKLLNYGFSR*"
     CDS             complement(5485..6692)
                     /protein_domains="PF00480"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415177"
                     /pseudo=False
                     /translation="VTEAVSAGQPAQAHPTGPGAVLALIRGGRATTRAQLMAATGLSRS
                     TMATRLEALSEAGYLEVSGAADSTGGRPAGSFRLRPDSGVLLVADIGGSHVHTALADMA
                     CDVLASHRRDLDVAEGPEVVLGQVAADFQRLLKEAGESAGRVRGIGVGVPGPVEAGTGR
                     VVSPPIMTGWDGYTVPDFFRDTYDCLVLADKDTNLMALGEHRVNWPDVPHLLFVKAGTG
                     IGSGLVLGGRLHHGSQGAAGDIGHIPAPGLDETSPDAPLCRCGNSGCLEALTGGWALVR
                     DLTAAGHEVATTDDVVNLVRSGNGDAVRLLRHAGRLLGQGVADAVSLLNPSILVVGGGL
                     AHAQEHLIAGIREVTYRRSLPLATRDLRVVLSPLATRAGVTGAAHMVADALFDPAAVDA
                     QLR*"
     CDS             6864..7729
                     /protein_domains="PF01261"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415178"
                     /pseudo=False
                     /translation="MNDLGVHALVWTGDWTPEGARTAAARSRAAGYDLVEISLHDPGIV
                     DVKATREVLAEYGLGVACSRGLAFDSDVSSDDPETAARGEALLRQALHITHDLGGDYFG
                     GVLYSALGKYGHPPTPKGREHAVQAVRRLAAEADGLGVTLGLEVVNRYESNLVNTAQQG
                     LELIDEIGAANVVVHLDTYHMNIEEQDFSRPVRACGDRLGYVHIGESNRGYLGSGTVDF
                     PAFFHALADIGYQGPITFESFSSAVVAPGLSHDLAVWRDLWSDGADLAAHARSYIADQL
                     KAAHATV*"
     CDS             7828..8447
                     /protein_domains="PF00485"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415179"
                     /pseudo=False
                     /translation="MTPQQLLERAQRLADADGRRLLGIAGPPGAGKTTLAEYLVDALGA
                     DRAVLVPMDGFHLADVELRRLGLTGRKGAPETFDPYGYTALLRRLRAPRPGETVYAPGF
                     DRELEQPVAGTIPVPPEIPLVITEGNYLLLDEAPWLPVRELLDESWWVDLDTEERVRRL
                     IDRHERFGKPRDEAERFVLTSDEANARLVAPGRTAADFVVRGG*"
     CDS             8448..10126
                     /protein_domains="PF00474"
                     /protein_domains="TIGR00813"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415180"
                     /pseudo=False
                     /translation="MTGTLNLGAVDWFLLAVYFGAIIAIGITTKRAVHTTGDFFLAGRS
                     MPAWITGLAFISANLGALEIIGGAANGAQYGAAAVHFYWLGAIPAMVFLGVVMMPFYYS
                     TRVHSVSEYLRRRFNNQTHLLNSVVFAVAQMLLAGVNLFALALIVKLLIGWPLWLSILL
                     SAVFVLAYITLGGLAGAIYGEVLQFFVILAGLIPIVVIGLHYVGGFSGLREAVQDPSLL
                     HTWQGTAPGHWTNPLGDWIGLAMGEGFVLAFGYWTTNFAEVQRSLAAKDLNAARRTPLI
                     AAFPKMALPLFTVVPGMIALVIIPKLGQPGGPTYNDVIPEMMQRFLPNGVLGIALTGLL
                     AAFMAGMAANISGFNTVFTYDIWKPYVVRGRDDRYYLKAGRYATVAGIAVSVAAAFVAS
                     EYNNIQNYIQLLFSFFNSPLFATFLLAMFWKRVTPWAGFWGMLSGTVAAATAHLSAYHI
                     GWFYPGGQVGPHDTINAQMANFYGALFAFVVDVLVTVAVTFVTKPKPVAELAGLVWGLP
                     DPDSPDAHEATVRQPWWKSPVVLGCIILALTAGLSVWLVVAA*"
     CDS             10142..10362
                     /SVM_predicted_precursor=True
                     /locus_tag="prodigal_1415181"
                     /pseudo=False
                     /translation="MTPGKTFDVRWLIAGLLGLYGAVLTVLGLTDSAAEVAKADGIRIN
                     LWIGLGLLAVATAFAAWAKLAPQGRDGS*"
     CDS             complement(10565..11163)
                     /protein_domains="PF00440"
                     /protein_domains="PF16925"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415182"
                     /pseudo=False
                     /translation="VARTGRPRGFDKDQTLARALELFWSRGYGATSIQDLVDALAVERG
                     SLYGTFGDKRRFYLDAVRLYWDVYERHLTAALDTSPLLPALREILTHPVRLDELISDVG
                     VPHGCLVGNTTAELVPHDSEATEIVTRSYRRFTDIVTDALRRAQAAGEVTDDARPEAQA
                     QLLLYLVQGLSLVSRADLDRTAALAAIDTAIEALRA*"
     CDS             11283..12031
                     /protein_domains="PF13561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415183"
                     /pseudo=False
                     /translation="MEFAGKTALITGSGAIGGLGHATARVLASQGADLIITGTDPERGA
                     QVVEDLRAAGGESTGTARFVAADVADPAAVRRLADDAGAVDILINNASLMTLAPTTEQD
                     IATYDAAFAVNVRAPFLLTALLATKMAAGGGGSIVNVSSTAAGLGMPGMAVYGATKAAI
                     ESLTRTWAAEFAASNVRVNAVAPGPMRTSKVVAAMGPDMGGMGLTTALKRTSDPAEVAQ
                     VIAFLASDRASYMTGAIVAADGGRTAI*"
     CDS             12123..12871
                     /protein_domains="PF13561"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415184"
                     /pseudo=False
                     /translation="MGRLDGKHALITGGTSGIGLETAREFLAEGASVAITGRSRERLDE
                     AARQLAGPLLTIVSDAGDVPGQAALASRLRAEWPKLDILMSNAADITHLPIEEWTEEAF
                     DRLLATNLKSPFFLIRDLLPLFSRQSSVILVGSVSAFIGHENATVYGAAKAGLLSYTRG
                     LTYELKDRGIRVNGLSPGPTFTNAFKPLGPERQAAVYEELRRTVPLHRIGTATEMAKAA
                     VYLASDESAYTAGTVLRVDGGIGELAY*"
     CDS             complement(12954..13957)
                     /protein_domains="PF00490"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415185"
                     /pseudo=False
                     /translation="LTSTYGDFPGARPRRLRTTPAMRRMVAETRLHPAELILPVFLRED
                     ITKPAPLEAMPGVVQHTRHSLRKAAAEAVEAGVGGIMIYGVPEESKKDATGTAGTDPDG
                     ILQVAIRDVRYEVGDDLVIMSDLCLDEYTDHGHCGVLDAEGRVDNDATLERYAEMARVQ
                     ADAGVHTVGPSGMMDGQVRVIREALDAAGHQDVSILAYTVKYASAFYGPFREAVGSSLK
                     GDRKTYQQDPANVRESLRELRLDLAEGADMVMVKPGLPYLDILRQIADAVDVPVAAYQV
                     SGEYAMIEAAAANGWIDRDRAIMEALTSVRRAGAGMILTYWATEVAQRLNRGE*"
     CDS             complement(13955..15618)
                     /protein_domains="PF02602"
                     /protein_domains="PF00590"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_1415186"
                     /pseudo=False
                     /translation="LNPNAPNHPGCGHVTFLGAGPGDPGLLTLRAVEALAAADVLIADP
                     HVLDVVREHVRPGVAADAQGTPRQADTDVSSGAATVPVLRDTANLVMTAARGGKRVVRA
                     VAGDPGLDGYAADEMLACAAEGIVFEVVPGVAAAVGVPAYAGVPLRDAKSADVRFVDAL
                     TADERCWSEVGSSGATAVVSATLETVAAAAGELVAAGRKPDTPLTVTVGGTTTRQRTWT
                     ATLGTIAQVLKSAKVLPSPQGAQPVIAVVGEQSEAGRRDQLSWFESKPLFGWKVLVPRT
                     KEQAASLSDQLRSYGAVPSEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVK
                     AVREKFEEYGLDARAFAGIKVAAVGEQTAKSLIDFGVKPDLVPSGEQSAAGLLEDWPPY
                     DPVFDPIDRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGG
                     FDAVLFTSSSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVLKLA
                     EALADFGAARRQAAIEAGEPVTRPSERRPGSRRRARS*"
ORIGIN
        1 atggcttcgg tcccttccct cgccgctacg gtccaccagc gcgtcgccga cgccctctcg
       61 gccgccctgc cggaggcggg ctccgccgac ccgctgctgc gacgaagcga ccgggccgac
      121 ttccaggcca acgggatgct ggcgctggcc aagaagctca agggaaaccc ccgggagctg
      181 gcctccaagg tcgtggcgca ccttccggtc gccgccacct cggccgaccc cgacccggtg
      241 atcgcggaca tcgaggtctc cggccccggc ttcctcaaca tctcgatcgc cgactccgcg
      301 atcaccgcga ccctcgccgc ccgcgccgcc gacgagcgcc tcggcgtgcc gtacgcggag
      361 gcgcccggca ccacggtgat cgactacgcc cagccgaacg tggccaagga gatgcacgtc
      421 ggccatctgc gctcggcggt gatcggcgac gcggtggtgc ggatcctgga gttcgcgggc
      481 gagaaggtga tccggcgcca ccacatcggc gactggggca cccagttcgg catgctcatc
      541 cagtacctga tcgagcaccc gcacgagctg gaccacaagg acgccgcctc cggccaggag
      601 gccatgtcca atctgaaccg gctctacaag gcggcgcggg cgctcttcga ctccgacccg
      661 gagttcaagg agcggtcccg gcggcgggtg gtggaccttc aggcgggcga cgaggagacc
      721 atcgccctgt ggcggaagtt cgtggacgag tcgaagatct acttctactc ggtcttcgac
      781 aagctcgaca tcgagatccg cgaccccgat gtggtcggcg agtcgggtta caacgacatg
      841 ctggccgaga cctgccggct gctggaggag tccggcgtcg ccgtgcgctc cgagggtgcc
      901 ctgtgcgtct tcttcgacga catcaagggc cccgagggca atccggtgcc gctgatcgtc
      961 cagaagtccg acggcggctt cggctacgcg gccaccgacc tgtccgcgat ccgcgaccgg
     1021 gtgcggaacc tgaaggccga caccctgctg tacgtggtgg acgcccgtca gtcgctgcac
     1081 ttcaagatgg tcttcgagac ggcccgccgg atcggctggc tgggtgaccg ggtgcacgcc
     1141 gtccagctcg ccttcggcac ggtcctgggc aaggacggca agccgttcaa gacccgcgag
     1201 ggcgagaccg tccggctgga ggacctgctg gacgaggcga ccgagcgggc ggcggccgtg
     1261 gtccgcgaga agagcgagaa gctcggcctc accgaggagg agatcctcga gcgcggtgcc
     1321 caggtcggca tcggcgcggt gaagtacgcc gacctgtcca cctccgcgtc gcgtgactac
     1381 aagttcgacc tcgaccagat ggtctcgctc aacggcgaca cctcggtcta tctgcagtac
     1441 gcgtacgccc ggatccagtc gatcctgcgc cgcgccgagg agggtcagcg gccgcgggcc
     1501 caccccgagc tgccgctggc cccggccgag cgggcgctgg gcctgcacct cgaccagttc
     1561 ggggagacgc tgcgcgatgt ggccgcgggg ttcgagccgc acaagctggc cgggtatctg
     1621 taccagctgg cctcgctcta cacgaccttc tacgaccagt gcccggtgct gaaggcggag
     1681 ggcggcccgg cccaggtgga gaaccgcctc ttcctgtgcg acatcacggc gcggacgctg
     1741 cggcagggca tgaccctgct gggcatccgc acccccgagc gcctctgacg cgaccgaacg
     1801 cggaagcgcc ccgcccccgg tgccgggggc ggggcgcttc cgcgttcccc ccggagtcca
     1861 ccgggcagcg ccggaccgca cggctcaggg cagctccggg ccacagcact tcagggcggc
     1921 gccgggccgc ggcgctcaga ggcggggcag catctcgggg gcagcgtctc aggggcagcg
     1981 cagatcgcgc ttcggcagct cgccggtcag caggaagtcc gtcacccgcc ggtccgcgca
     2041 gtcgctgccg tggttcaccc ggtaggccgc gccgtgcccc atcgcgtcca cgctgaccat
     2101 ccgggcccgg tctcgatagg cgcgccgcag ctcgagcgcc ccgcggtacg gagtggccac
     2161 atcgcgcgtg ttctgcacca gcaggacgtt cgacgggccc tgaccggtga tccgcaccgg
     2221 cttgtcccgc ggcttgtcgt gccagaacgc acaggtggtg acgttcaccg gcatcccagc
     2281 ggtcagcggg tggctcgtac ggctggcggc gacgtcccgc gcgtaggcgg tcagggaggt
     2341 gggccactcc acgtcgttgc agatggtcgc gagggacacg gccgcgatgt cctgggtggg
     2401 gtcggccggt gccgcgtcgg gcaccttgcc ggcgtccgcg tcgacgatca gcctggccag
     2461 gccctcgaag gtgtccgggg agtacagggc gctcagcatg ctctggcgga gcacattgcc
     2521 gttcagctcg ggcgggttgg cgccgggcca cggcagcggg ttcgcgtcca gccgagcggc
     2581 gagggccagg acccggcggc gcaccccgtc gggggtcccg gcgagccgga cggggctgcc
     2641 gggggcggag gcccaggcgg cgaagtcggg gaaggtgtcc tcgacgccga cggcgtagtt
     2701 ggcgagccag ccgcgctcca cccgttccgg gtccgggtcg tcgttgctgt ccagcaccca
     2761 gcggtcggtg tgctcgggga acatctgggc gtagacggag cccacgtacg tcccgtagga
     2821 gacgccccac gcggacagct tccgctcgcc gagcgcccgg cggatgctgt cgatgtcccg
     2881 tgcctcgttg acggtgctga gggtgcgcag caggtcaccg ccgttgcggg cgcaggtgtc
     2941 ggcgatgcgg cggccggtgg tgacgttctc cgtgatgtcc ccgccggggg cgggccaggg
     3001 ccgggaggcg agcagcgaca gatcggcggg ggccagatcg catccggcgt gcgtggaccg
     3061 ccccagaccg cgcggatcga agctgacgat gtcgtacgcg tcccgcaccg accgcggcag
     3121 ccgcttgccg agcgtggtgg gccggtccag gcccggcgac cccgggccgc ccgggatcag
     3181 cagcagcgtg ccccggcggg cccgcggccg ctcgctgggg acgcgggaga ccgcgaggga
     3241 gatccgcttg ccgccgggat cgcggtagtc cagcggcacc ttcagcgtgg cgcattcctg
     3301 acgggggtcg agtccggtgc cctcgcaggc cccccagccg agcgcggtgg cggtcgggcc
     3361 ggtctgccgc cgcggggtcg cgtccgcggc ggacacggtg ctgcccagga gggaggcggt
     3421 ggcggcggtg gcgagggcca ggacggcggt tctgccggtc gtcagtctca tggccgcaag
     3481 cctcgtggaa ccggtcgtcc gttcccatcc gggcaaccgg ccgcccggcc cgggggataa
     3541 ccccccaggg ggatcgtcag gcgtaccgtc gcgcacgtag cattcaggac agatttcccg
     3601 gaccgggaca acctctcgcc gtcccagccc gtccaactcc gtgcaccttc gtgcatcacc
     3661 tttcatcgac ggaccattgg gggcttgacc atgcgacggt ggcggaccgc actcgcggca
     3721 atggcgctcg cgggcggcgc gttggcggcg acggcgggaa cggcgggggc ggtggtcccg
     3781 gccgcggccg gagcccgggc cgggaccacc ggggccgggg ccacggcctg cgagaccggc
     3841 tggggcagcg gcgagaagac ggcccggccg gccggccaca caccgctgac gaacgtcagg
     3901 accggccggc acgcgtgctt cgaccgcatc gtgttcgatg tgcggggcgc cacggcggcc
     3961 ggtcccatcg gataccgcgt gggctacgtg aacgccctgc accaggacgg ttcgggcgag
     4021 gagatcccgg tcggcggcgg ggcgatcctg gagatccgcg tggccgcgcc gagctatgac
     4081 ccggggtccg gtgcggagtc gtatccgggg cgggcgcgca agccgctgcc gggagtggac
     4141 ctcaccggct accagacctt ccgggacacc cgcttcggcg ccagcttcga gggcgatacg
     4201 caggtcggcc tcggggtgcg ggcacggctg ccgttccggg tcctccagac ggacgggcat
     4261 gtcgtggtgg acgtggcgca ctcctggacc gcgctgcgct gagccgccca gaaccgcgac
     4321 ggggcctgtc ccgcgacctg gacggtcggt gcgggacagg ccccatgaca tgccgtgagc
     4381 ccgtagggct acctgctgaa gccgtagttc agcagcttct tcgcgtccgc ggtgcggttg
     4441 tccaccgagg aggaggcgag gacggtgccg atgaccgtct tgccgttccg ggtggcggcg
     4501 aagaccaggc agtacttggc ctccggaccc gaaccggtct tgacgccgat ggtgcccgag
     4561 tagctgccca gcaggttgtt ggtgttggtc cacgacatgt agcggtaacc gccgttcttc
     4621 gtggtcacct tctgcttcgt cgacttcgtc ttcacgaccg tgcggaaggt ggagtacttc
     4681 atcgcgctgc tggcgagctt ggtcagatcg cgcggtgtcg agtagttcgc gccgtgcccg
     4741 atgccgtcga acgagtcgaa gtgggtgttc gtcagcccga gcgacttggc ggtgctgttc
     4801 atcttgccga tgaacgactt cacccgagcg gcccgggtgg agccggtgcc gaacttgtcc
     4861 gccagcgcgt acgccgcgtc acagccggac gggagcatca gcccgtacag cagctggcgg
     4921 acggtgacct tgtcgccgac gatcagcttg gcggaggagg cccagttgtt gtcgacgatg
     4981 tagtcgctgt acgccttctg gaccgtgacc ttggcgtcca ggttgaggtt cggctgcgcg
     5041 agcaccaccc gagcggtcat gatcttggtg gtggagccgg tggaacggcg ggtgtccgcg
     5101 gccttggtga acaggctctt gcccgtgccg ttgttcatca cgaacccgcc cttggcgacg
     5161 atcgtgggag tagcggtcgt cgcggcctgc gcggaggcgg tgaacgcccc cgccgtcagc
     5221 acggctccag cggtgaccgt gaccgcggat acgcgacaaa gacccttcat gccggttttc
     5281 aacgtcaata tctccaaatg cccctggcct gcgaccacat aacagggccg ctccctgatg
     5341 agacgcacga gagggcccga tggatgtgcc ttctgtgaag acttccagga aattcccttg
     5401 ggcgcacgga cggcggcgac gcggtgccgg acgcatccgt cggggccgtc actccccgcg
     5461 cccggccccg ccccggcgca cgctcaccgc agctgggcgt ccaccgcggc cgggtcgaag
     5521 agggcgtcgg ccaccatatg ggcggcgccc gtgacgcccg cgcgggtggc cagcggggag
     5581 aggacgaccc gcagatcccg ggtggccagg ggcagcgaac ggcggtaggt gacctccctg
     5641 atgccggcga tcaggtgttc ctgggcatgg gcgaggccgc cgcccaccac caggatcgag
     5701 gggttgagca ggctgaccgc gtcggcgacg ccctggccga gcaggcgccc ggcgtggcgc
     5761 agcagccgta cggcgtcgcc gttgccggag cggaccaggt tcaccacgtc gtcggtggtg
     5821 gccacctcgt gcccggcggc ggtgaggtcg cgcaccagcg cccagccgcc ggtcagcgcc
     5881 tccagacagc cggagttgcc gcagcggcac aggggcgcgt ccggggaggt ctcgtcgagc
     5941 ccgggggcgg ggatgtggcc gatgtcaccg gccgcgccct gggagccgtg gtggagccgg
     6001 ccgccgagga cgagaccgga gccgattccg gtgcccgcct tgacgaagag caggtgcggg
     6061 acgtcgggcc agttgacccg gtgctcgccg agcgccatga ggttggtgtc cttgtcggcc
     6121 agcaccaggc agtcgtaggt gtcgcggaag aagtccggca ccgtgtagcc gtcccagccg
     6181 gtcatgatgg gcgggctgac cacccggccg gtgcccgcct cgaccgggcc cggcaccccg
     6241 acgccgatcc cgcgcacccg gccggcggac tcgcccgcct ccttcagcag ccgctggaag
     6301 tcggcggcca cctggccgag caccacctcc gggccctcgg ccacgtcgag gtcgcggcgg
     6361 tgcgaggcga ggacgtcaca ggccatgtcg gcgagcgcgg tgtgcacatg gctgccgccg
     6421 atgtcggcga ccagcagcac ccccgagtcg gggcgcagcc ggaaggagcc ggcggggcgg
     6481 ccgccggtgg agtcggccgc gccggagacc tccagatagc ccgcctcgct cagcgcctcc
     6541 agccgggtgg ccatggtgga ccgggagagg ccggtggccg ccatcagctg ggcccgggtg
     6601 gtcgcccggc cgccgcggat gagcgccagt accgcccccg ggcccgtggg atgcgcctgt
     6661 gctggctgac ctgccgagac cgcctccgtc actggcccct gtcctccgct gctcacgctc
     6721 tgttcggtac cgcgtacacc gtacctccct ttacgaccga tcccaagaaa acttatgtat
     6781 tgcctccacg caaaagatgc gtaacatcga gcacgcaatg acgcagagcg cgcccgaagg
     6841 gcaggcagca gaagggatcg tcatgaacga cctcggagtg cacgcactcg tgtggaccgg
     6901 cgactggacg cccgaaggcg cccggaccgc cgccgcgcgc agccgcgcgg ccgggtacga
     6961 cctggtcgag atctccctcc acgaccccgg gatcgtcgat gtgaaggcca cccgcgaggt
     7021 gctcgccgag tacggcctcg gcgtcgcctg ctcccgcggc ctcgccttcg actccgacgt
     7081 ctcctccgac gaccccgaga ccgccgcccg cggcgaggcg ctgctgcgcc aggccctgca
     7141 catcacccac gacctgggcg gcgactactt cggcggggtg ctctacagcg cgctcggcaa
     7201 gtacggccac ccgccgaccc ccaagggccg tgagcacgcc gtccaggccg tgcgcaggct
     7261 ggccgccgag gccgacgggc tcggggtgac cctcggcctg gaggtcgtca accgctacga
     7321 gtccaacctg gtcaacaccg cccagcaggg cctggagctg atcgacgaga tcggcgcggc
     7381 caatgtggtg gtccacctgg acacgtacca catgaacatc gaggagcagg acttctcccg
     7441 cccggtccgg gcctgcggcg accgcctcgg atacgtccac atcggcgagt ccaaccgcgg
     7501 ctacctcggc tccggcaccg tggacttccc cgccttcttc cacgccctcg cggacatcgg
     7561 ctaccaggga ccgatcacct tcgagtcctt ctcctccgcc gtcgtcgccc ccggcctctc
     7621 ccacgacctc gccgtctggc gcgatctgtg gtccgacggc gccgacctcg ccgcgcacgc
     7681 ccgctcgtac atcgccgacc agctcaaggc cgcccacgcg acggtctgag cacccacccg
     7741 gcccggccgc cccacaccgg ccgaccgccc gtcccccctg agcactccat cccgtaaact
     7801 ccccgaaacc gccgaaagcg cccgctatga ctccccagca actccttgag cgcgctcagc
     7861 gcctggccga cgcagacggc cgccgcctgc tcggcatcgc cggaccgccc ggggccggca
     7921 agaccaccct ggccgagtac ctggtcgacg ccctcggcgc cgaccgggcc gtcctggtgc
     7981 cgatggacgg cttccacctc gccgacgtcg aactgcggcg gctcggtctg accggccgca
     8041 agggcgcacc ggagaccttc gacccgtacg gctacaccgc gctgctgcgg cggctgcggg
     8101 cgccgcggcc cggggagacg gtgtacgcgc cgggattcga ccgcgagctc gagcagccgg
     8161 tcgcgggcac catcccggta ccgccggaga tcccgctggt gatcaccgag gggaactacc
     8221 tgctgctcga cgaggcgccc tggctcccgg tccgcgagct gctggacgag agctggtggg
     8281 tcgacctgga caccgaggag cgggtgcgcc ggctcatcga ccgccatgag cggttcggca
     8341 agccgcggga cgaggccgag cgcttcgtcc tcacctccga cgaggccaac gcccgtctgg
     8401 tcgcccccgg gcggacggcc gccgacttcg tggtgagggg cggctgatga ccggcaccct
     8461 gaacctggga gccgtcgact ggttcctgct cgccgtctac ttcggcgcga tcatcgccat
     8521 cggcatcacc accaagcggg ccgtccacac caccggtgac ttcttcctgg ccgggcgctc
     8581 gatgcccgcc tggatcaccg gcctggcctt catatccgcc aacctcggcg ccctggagat
     8641 catcggcggc gcggccaacg gcgcccagta cggcgccgcc gcggtgcact tctactggct
     8701 cggggccatc cccgcgatgg tcttcctcgg cgtcgtgatg atgccgttct actactcgac
     8761 gcgggtgcac agcgtctcgg agtatctgcg ccgccgcttc aacaaccaga cgcacctgct
     8821 caacagcgtc gtcttcgcgg tcgcccagat gctcctggcg ggcgtcaacc tcttcgcgct
     8881 cgccctgatc gtcaagctgc tgatcggctg gccgctgtgg ctgtccatcc tgctgtcggc
     8941 ggtcttcgtc ctcgcgtaca tcaccctggg cgggctcgcg ggagcgatct acggcgaggt
     9001 gctgcagttc ttcgtcatcc tcgccgggct gatcccgatc gtcgtcatcg gactgcacta
     9061 cgtgggcggc ttcagcggtc tcagggaggc cgtgcaggac cccagcctgc tgcacacctg
     9121 gcaggggacc gcaccgggcc actggaccaa tccgctcggc gactggatcg gcctggcgat
     9181 gggcgagggc ttcgtcctcg ccttcggcta ctggaccacc aacttcgccg aggtccagcg
     9241 gtccctggcc gccaaggacc tcaacgcggc ccgccgcacc ccgctgatcg ccgccttccc
     9301 caagatggcg ctcccgctgt tcaccgtggt ccccggcatg atcgcgctgg tcatcatccc
     9361 caagctgggg cagcccggcg ggcccacgta taacgacgtc atcccggaga tgatgcagcg
     9421 cttcctgccg aacggcgtgc tcggcatcgc gctcaccggc ctgctcgccg ccttcatggc
     9481 gggcatggcg gccaacatat ccggcttcaa cacggtcttc acctacgaca tctggaagcc
     9541 gtacgtggtc agggggcgcg acgaccgcta ctacctcaag gccgggcgct acgccacggt
     9601 cgcgggcatc gcggtgagcg tcgccgccgc gttcgtcgcc tccgagtaca acaacatcca
     9661 gaactacatc cagctgctgt tctcgttctt caactcgccg ctgttcgcga ccttcctgct
     9721 ggcgatgttc tggaagcggg tcaccccgtg ggcgggcttc tggggcatgc tgtccggcac
     9781 cgtcgcggcg gccaccgccc acctctccgc ctaccacatc ggctggttct accccggcgg
     9841 ccaggtcggc ccgcacgaca ccatcaacgc ccagatggcc aacttctacg gggcgctctt
     9901 cgccttcgtc gtggacgtgc tcgtcaccgt cgcggtcacc ttcgtcacca agcccaagcc
     9961 ggtcgccgaa ctggccggcc tggtctgggg cctgcccgac cccgactcgc cggacgccca
    10021 cgaggcgacc gtgcggcagc cctggtggaa gtccccggtg gtgctgggat gcatcatcct
    10081 ggcactgacg gcgggcctga gcgtctggct ggtggtggcc gcatgaagaa ggagagcccc
    10141 atgaccccgg gaaagacctt tgacgtgcga tggctgatcg ccgggctgct cggcctctac
    10201 ggcgcggtgc tgaccgtcct cggcctcacc gacagcgccg ccgaggtggc caaggcggac
    10261 ggcatccgca tcaacctgtg gatcggcctc ggcctgctgg ccgtcgccac cgccttcgcg
    10321 gcctgggcca agctggcccc gcaggggcgc gacgggagct gaaccggcgt tttgcgcggc
    10381 ggcccctgcc cggtcgggca ggggccgccg tacgtcagcg gcgcatggtc cgcgcgccgg
    10441 tcccggtgcc ggtatagccg gccgagcggg gtgggcggcc ggagggctgc cgccaccgcg
    10501 tcatggtcgg cgcggtccgc caccgggtga cccgaccgat cccccggccg gcgacggccg
    10561 cggtcacgcc cgcaatgcct cgatcgcggt gtcgatcgcg gccagggccg cggtcctgtc
    10621 gagatccgcc ctcgacacga gcgagaggcc ctggacgagg tagagcagga gctgggcctg
    10681 ggcctccggg cgggcgtcgt cggtgacctc tccggcggcc tgggcgcggc ggagtgcgtc
    10741 ggtgacgatg tcggtgaacc ggcgatagga gcgggtgacg atctccgtgg cttcgctgtc
    10801 gtgggggacg agttcggcgg tcgtgttgcc gaccaggcag ccgtgcggca cgcccacgtc
    10861 ggagatcagc tcgtccaggc gtaccgggtg ggtcaggatc tcgcgaagcg ccggcaggag
    10921 cgggctggtg tcgagtgcgg cggtcaggtg ccgctcgtac acgtcccagt agagccggac
    10981 ggcgtcgagg tagaagcggc gcttgtcgcc gaaggtcccg tagaggctgc cgcgttcgac
    11041 ggccagcgcg tcgaccaggt cctggatcga tgtcgccccg tatccccggg accagaacag
    11101 ctccagtgcg cgcgccagcg tctggtcctt gtcgaatcca cgggggcgtc cggttcgtgc
    11161 cacctgcccg acgctacaac ttcttgacag gtcgttcaag aagtcatagc ttccatcaca
    11221 tcactttttg aacggccgca cagaagtcgg cggccatgtg tcgggcacga agggcgacgc
    11281 catggagttc gcgggaaaga cagcactcat caccggatcc ggcgcgatcg ggggactcgg
    11341 gcacgcgacg gccagggtcc tggcctcgca gggagccgac ctgatcatca ccggcaccga
    11401 tccggagcgc ggcgcccagg tcgtggagga cctccgcgcg gccggtggcg agtccaccgg
    11461 gacggcgcgt ttcgtcgcgg ccgatgtggc cgacccggcg gccgtgcgcc ggctggccga
    11521 cgacgccgga gccgtggaca tattgatcaa caatgcgagc ctcatgacgc tcgccccgac
    11581 caccgagcag gacatcgcga cctacgacgc cgccttcgcg gtcaatgtgc gtgcgccgtt
    11641 cctgctcacc gcgctgctcg cgacgaaaat ggccgcgggc ggcggcggca gcatcgtcaa
    11701 cgtcagctct accgcggccg gcctcggcat gccgggaatg gctgtttacg gcgccaccaa
    11761 ggcggcgatc gaatcgttga cccgcacctg ggcggccgag ttcgccgcgt cgaacgtgcg
    11821 cgtcaacgcc gtcgctccgg gtccgatgcg cacttcgaag gtggtcgcgg cgatgggccc
    11881 ggacatgggc ggcatgggcc tgaccaccgc gctcaagcgc acctccgacc cggccgaagt
    11941 ggcccaggtg atcgcttttc tcgccagcga ccgagccagt tatatgaccg gggcgatcgt
    12001 ggccgctgac ggtggccgga ccgcgatctg aggccgccgg ccgaatactg ccccgtaccg
    12061 acggggacag ccgtcattcg tcacaccacg cgccgcggcg ccacataagg agaaagagtc
    12121 catgggtcgt cttgacggaa agcacgcact gatcacagga gggacgagcg gcattggcct
    12181 ggagacggcc cgtgagttcc tcgccgaggg agcgtctgtc gcgatcaccg gccgctcgcg
    12241 ggaaagactg gacgaggccg cccggcagct ggcgggtccg ctgctgacca tcgtcagcga
    12301 cgccggtgac gtacccggcc aggcggcgct cgcatcgcgg ctgcgggcgg aatggcccaa
    12361 gctcgacatt ctgatgagca acgccgccga catcacccat ctcccgatcg aggaatggac
    12421 cgaggaggca ttcgacaggc tcctcgcgac caatctgaaa tcaccgttct tcttgatcag
    12481 agatttgttg ccgctcttct cgcggcaatc ctcggtcatt ctcgtcggtt cggtttccgc
    12541 tttcatcgga cacgagaacg cgacggtcta cggtgcggcc aaggcgggcc tgctgtccta
    12601 tacccgcggg ctgacctatg agctgaagga ccggggtatc cgtgtcaacg gtctgagccc
    12661 gggtccgacg ttcaccaatg cgttcaagcc gcttggtccc gagcgccagg ccgccgtcta
    12721 cgaggaactt cggcggaccg tgccgctcca tcgcataggg accgccaccg aaatggcgaa
    12781 ggcagccgtc tatctcgcct cggacgagtc cgcctacacc gccggcaccg tgctgcgcgt
    12841 cgatggcggc atcggggagc ttgcctacta gccagggcct gccgtgcgac gcggccgggc
    12901 cggatgcgcc tgatgcgcgt ccggcccgtt ccgtccgtgt cagggggagg tgctactccc
    12961 cccggttcag ccgctgcgcg acctccgtcg cccagtacgt gaggatcatc cccgcgcccg
    13021 cgcgccgcac cgaggtcagc gcctccatga tcgcgcggtc gcggtcgatc cagccgttgg
    13081 ccgcggccgc ctcgatcatc gcgtactcgc cggagacctg gtacgccgcc accggcacgt
    13141 ccacggcgtc ggcgatctgg cgcaggatgt ccaggtacgg caggcccggc ttgaccatga
    13201 ccatgtccgc gccctcggcc aggtccagcc gcagctcgcg cagggactcc cggacgttgg
    13261 ccgggtcctg ctggtacgtc ttgcggtcgc ccttgaggga cgagcccacc gcctcgcgga
    13321 acgggccgta gaaggcggag gcgtacttca cggtgtaggc gaggatcgac acgtcctggt
    13381 gcccggcggc gtccagcgcc tcgcggatca cccggacctg gccgtccatc atcccgctgg
    13441 ggcccaccgt gtggacgccc gcgtcggcct ggacgcgggc catctcggcg taccgctcca
    13501 gcgtggcgtc gttgtccacc cggccctcgg cgtccagcac cccgcagtgg ccgtggtcgg
    13561 tgtactcgtc caggcacagg tcggacatga tcaccaggtc gtcgccgacc tcgtaccgca
    13621 cgtcccggat ggccacctgg agaatgccgt ccgggtcggt gcccgccgtg ccggtggcgt
    13681 ccttcttgga ctcctccgga acgccgtaga tcatgatccc gccgacgccc gcctcgaccg
    13741 cttcggccgc cgccttccgc aggctgtgcc gggtgtgctg cacgacgccc ggcatggcct
    13801 ccagcggcgc cggcttggtg atgtcctccc gcaggaagac cggcaggatc agctccgccg
    13861 gatgcagccg ggtctccgcg accatccgcc gcatcgcggg cgtggtgcgc agccggcgcg
    13921 gccgtgcacc ggggaagtcg ccgtacgtgc tggtcaagag cgtgccctcc tacgtgatcc
    13981 cggccgtcgc tcgctcgggc gggtgaccgg ctcgccggcc tcgatcgcgg cctgccgccg
    14041 cgccgccccg aagtccgcga gtgcctcggc gagcttgagc accgagggct cgggcgacag
    14101 cacatccacc cgcagtccgt gctcctccgc ggtcttcgcg gtggccgggc cgatacaggc
    14161 gatgacagtg acgttgtgcg gcttgcccgc gatgccgacg aggttccgca cggtggacga
    14221 cgaggtgaac agcaccgcgt cgaacccgcc ccccttgatg gcctcacggg tctcggccgg
    14281 cggcggcgag gcgcgcacgg tgcggtaggc ggtcacgtcg tccacctccc agcccagctc
    14341 gatcagcccg gcgaccaggg tctcggtggc gatgtcggca cgcggcagga acacgcggtc
    14401 gatcgggtcg aagaccgggt cgtacggcgg ccagtcctcc agcagcccgg ccgcggactg
    14461 ctcaccgctg ggcaccagat ccggcttcac cccgaagtcg atcagggact tggcggtctg
    14521 ctcgcccacc gccgcgacct tgatcccggc gaacgcgcgg gcatcgagcc cgtactcctc
    14581 gaacttctcc cgcaccgcct tgaccgcgtt gaccgaggtg aaggcgatcc actcgtagcg
    14641 cccggtgacc agccccttga ccgcgcgctc catctgctgc ggggtgcgcg gcggctccac
    14701 ggcgatggtc ggcacctcgc tgggcaccgc gccgtaactg cgcagctggt ccgagagcga
    14761 ggcggcctgc tccttggtgc gcggcaccag gaccttccag ccgaacagcg gcttggactc
    14821 gaaccatgac agctgatcgc gccggccggc ctcgctctgc tcgccgacca cggctatcac
    14881 gggctgcgcg ccctgcggcg acggcagcac cttcgccgac ttcagcacct gggcgatggt
    14941 ccccagcgtc gcggtccagg tccgctggcg ggtggtggtg ccgccgacgg tgacggtcag
    15001 cggggtgtcc ggcttgcggc ccgcggccac cagctcaccc gcggcggcgg ccaccgtctc
    15061 cagggtcgcg gagaccacgg cggtcgcgcc ggacgagccg acctcgctcc agcagcgctc
    15121 gtcggcggtc agggcgtcca cgaaacgcac gtccgcgctc ttggcgtccc gcagcggcac
    15181 ccccgcgtag gcgggcacgc ccaccgcggc ggccacaccc ggcaccacct cgaagacgat
    15241 gccctcggcg gcgcaggcga gcatctcgtc ggcggcgtaa ccgtcgagtc cggggtcgcc
    15301 cgcgaccgcg cggacgaccc gcttgccgcc gcgtgcggcc gtcatgacaa gattggcggt
    15361 gtcccggagt accgggacgg tggcggcgcc tgacgacaca tcagtgtccg cctgccgcgg
    15421 tgtgccctga gcgtccgcgg ccacgcccgg cctgacgtgc tcgcgcacca cgtcgagcac
    15481 gtgcgggtcg gcgatcagca catccgcggc ggccagcgcc tccacggctc gcaaggtcag
    15541 caggcccgga tctcctgggc ccgcaccgag gaaggtgacg tgtccgcagc cggggtggtt
    15601 cggggcgttg gggttcaa
//
