LOCUS       reptomyces_RBGC_649706 16772 bp    DNA              BCT 09-SEP-2019
DEFINITION  RiPPTIDE predicted RiPP gene cluster.
ACCESSION   Streptomyces_RBGC_649706
VERSION     Streptomyces_RBGC_649706
KEYWORDS    RiPPs; RiPPTIDE.
SOURCE      GCF_000377525.1
  ORGANISM  GCF_000377525.1
            .
FEATURES             Location/Qualifiers
     CDS             2..1194
                     /protein_domains="PF00970"
                     /protein_domains="PF00175"
                     /protein_domains="PF00042"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548809"
                     /pseudo=False
                     /translation="MLSEKATPVVRATLPIVGAALGDITELFYRKLFDAHPELLRDLFN
                     RGNQANGEQRKALAGSIAAFAGMLLEQPGTRPDAMLARIAHKHASLGVTSGQYKIVHRH
                     LFAAMAEVLGDAVTDEVAAAWDEVYWLMANALIAVETRLYQEAGATEGEVWRTMEIAGR
                     RQETPDVVSFLLRPRDGRPAGTFRAGQYVGVRAELADGARQIRQYSLSTAPGRPEWRIS
                     VKRVRGATGPEGEVSSWLHEHAHPGDVLTVSVPFGDLVLPEGGEPLLLASAGIGNTPVL
                     ALLDHLVSTGSGRTVVTVHADRTPADHAHREEHLALARALPGGRLHLWYASPGHDAPDV
                     PAGRADLDGLDLPEDLTAYLCGPLPFMRTVRSDLLRRGIPAERIHYEVFGPDLWLGR*"
     CDS             1504..1931
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548810"
                     /pseudo=False
                     /translation="MNTPWAAVAAATAFVWFGMVLAISFIEAPLKFRAPDVTLRIGLGI
                     GRLVFRALNRAEAVLAAVLVVAVAAGGLPAPVVVPSVLVVGLLLAQLLAVRPVLNRRSD
                     RVLAGEDVPRSRAHLVYIACESAKALLLPALGVAALSV*"
     CDS             2047..2237
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548811"
                     /pseudo=False
                     /translation="MPGRRTEPARSFATAGRTGVLLFDDSASWVRTPGLRERPGALGAP
                     NGDTVACDAQSDSSHSSR*"
     CDS             complement(2208..3091)
                     /protein_domains="PF01636"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548812"
                     /pseudo=False
                     /translation="VRPRGPGFSCASETGWPATGRSGENERMIACSPQGPVEPPRVVTE
                     LAAGQPVRAVWKNTLGGLTFQVGSGDTRRFVKWTPAGSGVDLAAEVARLGWAARYTVVP
                     RVLGEGADASGSWIVTRSLPGRTAVDEHWKRDPGTAVRAVGSGLRALHDALPVADCPFG
                     WSAERRLERARSRAAAGRTHPADWHPDLRHFGTVERALGLLGDIPPVDRLVVCHGDACS
                     PNTLVGDDGRCTGHVDLGTLGVADRWADLAVATWSARWNYGPGWEEALLEAYGVEQDPE
                     RTMYYRLLWELSD*"
     CDS             complement(3139..3917)
                     /protein_domains="PF05013"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548813"
                     /pseudo=False
                     /translation="VSSFRLVPGAGDSPVVLHVPHSSREIPEPVRRGIELDDAALTIEL
                     DHITDAHTAALSAAAADAAALRPWQFVNGLSRLVVDPERFPDGREEMLAAGMGAVYTRT
                     THRERLRPEDADPQPLLDRYFHPYARAMTAVVADRLAAAGRAVVIDVHSYPTAPLPYEL
                     HGDGPRPPVCLGTDAFHTPPGLLAAAERAFAGFGGTGRDSPFAGTYVPLDFHRRDPRVS
                     ALMIEIRRDVYMTEPGGPAGPGLDRLGAALAQLVDSL*"
     CDS             3943..4118
                     /SVM_predicted_precursor=True
                     /pseudo=False
                     /translation="MVLGAWCLVLGAWCLVPGAWRPAADAISRTPLRRAPVRSINIELI
                     SDATSLFSGCGWL"
     CDS             4235..6891
                     /protein_domains="PF08376"
                     /protein_domains="PF02518"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548814"
                     /pseudo=False
                     /translation="MSPIQRIGSRGPSAKRRRRTLRLRTLLIWLAVVPIVALGVQSVLA
                     ANRLLEQSGHLRADVESGERIGIPLYRLMVAMQSERTLTAARWAGTGVPEDLMRERRAA
                     TDQAATAFRRSWEPGTAVSEVADRRLLEVAEGLGELDAYRERTDSGSGNADSTLVFYTG
                     VIGQMIRFYQDELSHTEDGGLIEDTRVVSAMFAASEMVAQEDMIIAQAGPSRTLTPSRF
                     ADLVNAVGAQRYLYDTWVVPYLPDAQNDLYAQMVRSGAWQTKTRIESAVLSEQTITDDG
                     VKLPRDVNGWRAAQQQWGPQLTTLNADRSQALLDRADARATDLETDVAWLIAGSIAALL
                     AVAAVVALTTGSVLRRLSRLHHRTVTIAERVLPDVVDRLQSGRPVDTAALPTVRGEKDE
                     VGRVNDAFARVVAVSVDGHTQLAAERQGFGMFAAGIASRTGNLVSRQLSLTEELQDAFG
                     HDEALLAQLMRADQLTVGMRRQIENLLILSGGEIPDPHTEPMRIADLLREAAAEVEDFR
                     RIERQALDEISIEAAVISQVSHLLAELLDNATRFSPPRSKVVIRAELVADGMSVEIEDR
                     GPRVAPATYEEMNGRLHSAPPYAVLAENAHRLGLFVVGHLADGLGATVTLRRSVYGGTS
                     AVVILPRELLVPTRNETGGAPDAPVRGESPADAPVRGEFPADAVHELPPSAEDAGVRSV
                     RAEPALATDGRGEGEVGAEPVRRTDAGLPVRGSHGRTPGRPDGESPGRSAGEPPEPDGE
                     PTALDAVSPGRPYGLVPRQPGGKSPGRPRAALPERAAKPSGDRTAEPPHRRPPPPPPSA
                     RPVRPVGPARDVRPALPERVPQTHMAEQLLGPRRATEAAAVREADTPEEVADAWADYEQ
                     GTQTVEDELRQDQR*"
     CDS             6889..7292
                     /protein_domains="PF03259"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548815"
                     /pseudo=False
                     /translation="MTTTSNDMIYSVLDNNLSRIADIKGAVLLSNDGIMLSSYLLDRPQ
                     GERIAAASSGIASTMKAISGDVDGGRVIRQLVEMEDRYLCIVGCGEGSTLIVVTSRKAR
                     LGELGGEAVRTAQALGEWLSTPGRGQAPTS*"
     CDS             7293..7657
                     /protein_domains="PF05331"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548816"
                     /pseudo=False
                     /translation="MTEASRRAGGRRTRLYALTDGRTTAPPVSLTMDTTVTAAVSADAY
                     DGLPSEWQAVLSLCVPPNGLAVAEIAARMHMRLTPTILLLGELEDRGLVRHRSPLEETE
                     TTNVNLLMRIRDNLARI*"
     CDS             7645..8234
                     /protein_domains="PF03029"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548817"
                     /pseudo=False
                     /translation="LPGYDTSAQEVAPVKILVAGGFGVGKTTLVETISEIEPLRTEERL
                     TAAGVGVDDLRGIESKSLTTVAMDFGRITLTDAGVVLYLFGTPGQERFWFMWDDLLDGA
                     LGAIVLVDTRRLDRSFPAVDFFESRGLPFVVGANCFHGEQLYSPEEIRSALHLRDPDTP
                     VLMLDARMRADVRAALLALLDMLIAKAGTVARV*"
     CDS             complement(8715..9496)
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548818"
                     /pseudo=False
                     /translation="MRTVRVLTAGLLAAAALFTLPFPGVAAVDSPSPSASTGDEGAAPT
                     EAGTSFRTATVIRPGQRATAQASTGDYLYWQFPADAGQRATVRATVELPRSTAGRGTRT
                     WRLDVYDGLRRRQACRYGSDTRAVPAGASSVELSCALRTVRAWSEPWANDPLPGAYYVR
                     LTVVTAPAEDLGEPAEAAVEVVTADSGGATAVDGRLAAPLVPASGRDVEPDGGWASGWW
                     SSRILWTACGAVLAALAGIWGHRLTRGGGRPAHVPPGA*"
     CDS             complement(9497..10851)
                     /protein_domains="PF13519"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548819"
                     /pseudo=False
                     /translation="LGRTGPAHYDPPMIIRKRLAAVLGGALLVTLTGGLLPSAASADSG
                     GTADRAAAKEPPKVELVLDVSGSMRARDIDGQSRMSAAKQAFNEVLDAVAEDVRLGIRT
                     LGADYPGKDRKEGCKDTRQLYPVGELDRTEAKAAVATLVPTGWTPIGPALLGAADDLEG
                     GDATRRIVLITDGEDTCAPLDPCEVAREIAAKGVGITIDTLGLVPNARMRAQLMCIAEA
                     TGGTYSSVQHKEELSERVGQLVDRAAEPVVTPVATQGGDRCADAPRLKAGLYADREAFG
                     QHRWYRVDLLPGQELRASVSISVDRPVNRDHGVLLRASTLAGREIVRGESTGDGRTDVV
                     STGLRYPKADTGDSGDAGDSGDAGDSGPAAETVCLRVSNSFSAPASVRTSPGLPLELTI
                     DITGGPRDAGDAAFLGLGHGWWLLGLLTLAGFAAGALWGWISRWRIAVWRSN*"
     CDS             11021..11454
                     /protein_domains="PF18029"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548820"
                     /pseudo=False
                     /translation="MASIRQFQVTFDCANPERVARFWCEVLGYVVPPPPKGFADWDEFD
                     RTLPPERRGCWFACVDPSGVGPRLFFQRVPEGKTVKNRLHLDVRVGTGLVGEERLAVLE
                     AECARLVALGAVRVRLLRADGVNESCLVMQDVEGNEFCLD*"
     CDS             complement(11568..14437)
                     /protein_domains="PF00005"
                     /protein_domains="PF00664"
                     /protein_domains="TIGR03797"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548821"
                     /pseudo=False
                     /translation="VIPVQPGHHAGSARPDDAVLAAFGGLGQHVDCAGLRSLPLEGPQV
                     LWLLVDGALDLFAVDAARQGQWHFLGRLEQGTLLLGPVEGPQHTLVGRPLQGCVLRRIP
                     LLELRPQSGYGDAWSYQSPYQSGYDSQDGTLSLLEHAFALGVGRGQRVLFEAPLDGRTA
                     DDDAVTDDDVLWLPVFPGSVQYGAAFSAEAAAGLLVDGALWQQMVNQQYRLLSGLDRWI
                     ERMEQAHEDRAAAGIKAGEAVRAGADQALLASIGRSRGASSARSRNAVSDDAAYAVCRL
                     VASTAGITLTEPPRGGPVDERTGPVERIALASRVRTRAVRLDGRWWREDCGPLVGHRAK
                     SGAPVALLWRRGGYRAVNPATGSRIRVDEENAEEFEPRAVMFYRPLPERPMSLWRLMVF
                     SLRGSRTDVRNLAVAGLVAVLLGAVVPVATGKVLGEYVPGARTDLIVQVSVAVMVAGGV
                     SAVFMLMQNLTVLRLEGRIESTLQPAVWDRLLRLPTKFFAERSTGELASAAMGISAIRR
                     LLSGVGPVVVQASTVGAMNMVLLLVYSVPLALAAIGMLLVIGTVFLGMGLWQLRWQRRL
                     VELNNKLNNQAFQTLRGLPKLRVAAAESFAYAAWAKQFARSRELHRRAGRIRNLTTVLD
                     AVYLPLSALIMFMLLAGPASGSLTAGEFLTFHTAVTMMLTSVTQLTGALVSAAAVLPMF
                     EQVKPVLDEAPEVRGTSTQPGGLSGAIETRKVSFRYTDDGPLVLDGVSLSVEPGEFVAI
                     VGPSGCGKSTLLRMLIGFDRPASGSVLYDGQDLAALDQAAVRRQCGVVLQNSQPFTGSI
                     LDCIRGAEPFTEEEAWAAAEMAGLAEDIRRMPMGMQTMISGSGAISGGQRQRLMIAQAL
                     VRRPRVLFFDEATSALDNATQRIVTESTRALRATRVVIAHRLSTVMDADRVIVMSEGRV
                     VQQGPPARLLAEVGGRLHELVRRQLM*"
     CDS             complement(14440..16772)
                     /protein_domains="PF03412"
                     /protein_domains="PF00005"
                     /protein_domains="PF00664"
                     /protein_domains="TIGR03796"
                     /SVM_predicted_precursor=False
                     /locus_tag="prodigal_4548822"
                     /pseudo=False
                     /translation="VTAPSPTPGSTTSGSTTPRSTGRSTGRTTARTTARTAGGRRGGDQ
                     RRANPRRARKPAAPARRKSVRTPTVLQMEAVECGAAALAMVLAHYGRHVPLEELRIACG
                     VSRDGSRASNILKAARGYGLQAKGMQMEPAALAGVRPPAILFWEFNHYVVHDGMGRRLG
                     RRGVHINDPDKGRRFVSMEDFDTSFTGVVLVFEPGDGFRRGGRRPGVLRSVPARLRGTT
                     GTMLAALVASLLLVAVGAALPALSRTYIDMYLVGRQTSLLGVLFASMAAMVALTAVLTG
                     LQQANLLRGRVISSTLSSARFFRHLLRLPVTFFGQRSPADLVQRLQSNDAVAETLARDL
                     TAFAVDGVVVLLYALLLWTYDPQLTVVGVLIALLNVVAMRIVVRLRATRTQKLRADSAR
                     LTNTSYTGIQLIETMKATGGENGYFRRWAGQHAITLEEQQRLGVPSAALAVVAPALATL
                     NSGLILWIGGMRAVEGHISIGLLVAFQALVTRFTAPITRLNGMASRIQDFAADVARLKD
                     VENFPADGLYTRPEPPASTRRLRGHVTLENIAFGYSPLDKPLLTGFSLSVGPGSQVALV
                     GGSGSGKSTVSRLIAGLYSPWEGVIRIDGRRLDEIPRGALAASVSFVDQEVFLFEGTVR
                     DNVALWDPSITDEAVADALRDAELYDVVARRPGGVHGRVEQDGRNFSGGQRQRLEIARA
                     LVRRPSVLVLDEVTSALDAETEQLIIDNLRRRGCACVVIAHRLSTVRDSDEIVVLDHGT
                     VVERGRHEELLARGGAYAELVKEH*"
ORIGIN
        1 atgctctccg aaaaggccac tcccgtcgtc cgggccacgc ttccgatcgt cggggccgcc
       61 ctgggggaca tcaccgagct cttctaccgc aagctgttcg acgcccaccc cgagctgctg
      121 agagacctgt tcaaccgcgg caaccaggcg aacggggagc agcggaaggc gctggccggt
      181 tcgatcgccg ccttcgccgg aatgctgctg gagcagcccg gcacccgccc ggacgcgatg
      241 ctcgcccgga tcgcgcacaa gcacgcctca ctcggcgtca cctccggcca gtacaagatc
      301 gttcatcgcc atctgttcgc ggcgatggcg gaggtgctcg gtgacgcggt cacggacgag
      361 gtcgccgcgg cctgggacga ggtgtactgg ctgatggcca acgccctgat cgccgtcgag
      421 acgcgcctct accaggaggc cggcgccacc gagggcgagg tctggcggac catggagatc
      481 gccggacggc gtcaggagac gcccgatgtc gtctccttcc tgctgcggcc ccgagacggc
      541 cggcccgccg gaaccttccg ggcgggccag tacgtcggcg tgcgagccga actggccgac
      601 ggcgcccggc agatccgcca gtacagcctg tccaccgccc ccggccggcc ggagtggcgg
      661 atcagcgtca agagggtccg cggcgcgacc ggaccggagg gcgaggtgtc gtcctggctc
      721 cacgagcacg cgcacccggg cgacgtgctg acggtgtcgg tgcccttcgg cgacctcgtc
      781 ctgcctgagg gcggcgaacc gctgctgctg gcgtccgcgg ggatcgggaa cacgcccgta
      841 ctggccctgc tcgaccacct ggtgtccacc ggctcgggcc gcaccgtcgt cacggtccac
      901 gccgaccgca cccccgccga ccacgcccat cgcgaggagc acctcgccct ggcgcgcgcg
      961 ctgccgggcg gccggctcca cctgtggtac gcgtcgcccg gccacgacgc cccggacgtc
     1021 ccggcgggcc gggccgacct ggacggcctg gacctcccgg aggacctgac cgcgtatctg
     1081 tgcggtccac tgcccttcat gcgtacggta cgaagtgacc tgctccgcag gggcataccc
     1141 gccgagagga tccactacga ggtcttcgga ccggacctct ggctcggccg gtaggagcgt
     1201 cggtccgcga gcgatggcac cggggcggcg ggggtgcgcg cttccccggt gcggtcggcg
     1261 ccgcaccggg tacgggtcgg ccgaccggtg gagacgggcg tcgagacgcc tcgaaggccg
     1321 tcgagggtat cgagcagcgc cggggcgcac cggtctcggt gcgccggatc cgaagagggg
     1381 cccaggcgcg ccgggaactg cccgctcgag gaatgccccc gcacgaggag tccccccgcc
     1441 cccgcagcga ggaaagcgcc cgcacgagga atccccccgc acgaggaaga ggtacaccgc
     1501 ggatgaacac cccctgggcg gccgtggccg ccgcgaccgc cttcgtctgg ttcgggatgg
     1561 tgctcgccat ctcgttcatc gaggcgcccc tcaagttccg ggccccggac gtgaccctgc
     1621 ggatcggtct cggcatcggc cgactcgtct tccgcgcgct caatcgcgcc gaagccgtcc
     1681 tggccgccgt gctggtcgtg gcggtcgccg ccggcggcct ccccgccccc gtcgtggtcc
     1741 cttcggtcct cgtcgtcggg ctgctgctcg cgcagctcct cgccgtccgg cccgtcctca
     1801 accgccgctc ggaccgggtg ctggccgggg aggacgtccc gcgctcccgc gcccatctcg
     1861 tctacatcgc ctgcgagtcg gccaaggcgc tcctcctgcc ggcgctgggc gtcgccgcgc
     1921 tgtcggtctg aacgcgccga cacggccgcg gggttggcgg cggcgcgcac gtacgcacgg
     1981 ctctcaggtg tccgaccggg gcgcctgagg cgcactcagg ttccggccgg tggtgcggag
     2041 ccttcatgcc cgggcgccgt acggagcccg cccgctcctt cgcgaccgct ggacggaccg
     2101 gggtgctcct gttcgacgac tccgcctcgt gggtgcggac ccccgggctg cgcgagcggc
     2161 ccggggctct gggtgctccg aacggcgaca ccgtggcgtg cgatgctcag tccgacagtt
     2221 cccacagcag ccggtagtac atggtccgtt ccgggtcctg ctcgactccg taggcttcga
     2281 gcagtgcttc ctcccacccc ggaccgtagt tccaccgggc actccatgtg gcgacggcga
     2341 gatcggccca gcggtcggcc acaccgaggg tgccgaggtc cacgtgaccc gtgcacctgc
     2401 cgtcgtcgcc gaccagggtg ttgggagagc aggcgtcgcc atggcagacg acgagccggt
     2461 cgacgggcgg gatgtcgccg agaagaccga gcgcgcgctc gacggtgccg aagtgccgaa
     2521 ggtccggatg ccagtccgcg ggatgggtcc ggcccgccgc cgctcgtgac cgagcacgct
     2581 ccaggcgccg ttcggccgac cagccgaacg ggcagtccgc gacgggcagc gcgtcgtgca
     2641 gcgcccgcag cccggaaccg accgcgcgta ccgcggtgcc ggggtcgcgt ttccagtgct
     2701 cgtccaccgc cgtacgtccg ggcaagctgc gggtgacgat ccatgatccc gatgcgtccg
     2761 cgccctcacc gagcacccgt ggcaccaccg tgtacctcgc cgcccacccc agacgtgcca
     2821 cctcggccgc gagatcgaca ccgctgccgg ccggcgtcca cttcacgaac cgccgcgtat
     2881 cgcccgagcc gacttggaac gtcaacccac cgagggtgtt cttccagacg gcccgaaccg
     2941 gctgccccgc cgcgagctcg gtgacgacgc gtggaggctc gactggcccc tgtggcgagc
     3001 aggcgatcat ccgttcattc tcgccggagc ggccggtggc cggccaaccc gtttcggacg
     3061 cgcacgagaa gcccgggccc cgcgggcgca ccgccggcct cggcgcccgc ggggccgcgg
     3121 gccggtccgg acgtcgctca gagcgagtcg accagctgcg ccagggcggc gcccagccgg
     3181 tccagtcccg ggcccgcggg ccccccgggt tcggtcatgt agacgtcgcg gcggatctcg
     3241 atcatcaggg cgctcacgcg agggtccctg cggtggaagt cgagtgggac gtacgtaccc
     3301 gcgaaggggc tgtcgcgccc ggtgccgccg aagcccgcga acgcccgctc ggcggcggcg
     3361 aggagcccgg gcggggtgtg gaaggcgtcc gtgcccaggc agaccggcgg tcggggcccg
     3421 tcgccgtgca gctcgtaggg cagcggggcc gtggggtacg agtgcacgtc gatgacgacc
     3481 gcccgtccgg cggccgcgag gcggtcggcc acgacggcgg tcatggcccg tgcatacggg
     3541 tggaagtacc ggtcgaggag cggctgcggg tcggcgtcct ccggccggag ccgctcgcgg
     3601 tgcgtggtcc tggtgtagac cgcgcccatg cctgcggcga gcatctcctc gcgcccgtcg
     3661 gggaatcgct ccgggtcgac caccagccgg gagagcccgt tgacgaactg ccacggcctg
     3721 agcgcggccg cgtccgccgc cgcggcggag agggcggcgg tgtgggcatc ggtgatgtga
     3781 tcgagctcga tcgtcagcgc ggcgtcgtcc agctcgatgc cgcgccgcac cggttcggga
     3841 atctcccgcg aggagtgcgg gacgtggagc acgacggggg agtcgccggc gcccggaacg
     3901 agacggaagg aggacacgga caacgatcct acggccggtg cttggtgctt ggtgcttggt
     3961 gcttggtgct tggtgcctgg tgcctggtgc ctggtgcctg gcgaccggcg gccgacgcca
     4021 tctcccggac cccgctccgg agggcccccg ttcgctccat taacatcgaa ctgatttctg
     4081 acgcaacctc tcttttttct gggtgtggct ggttatgatc ggcctcctca tccctggtcc
     4141 cgacctggcc ggaacggtgt ttcccgagtg ccccggggca gcgccccggc ccggtcgacg
     4201 gtccgtcacg ctgtcccccg ctcctgagga ctgatgtcac cgatacaacg catcgggtcg
     4261 cgaggcccgt cggcgaagcg ccggcggcgc acgctgcgcc tgcgtacgct gctcatctgg
     4321 ctcgcggtcg ttcccatcgt ggccctgggc gtgcaatccg tcctggccgc gaaccggttg
     4381 ctggaacagt cggggcacct gcgcgccgac gtggagtccg gtgaacggat cggcataccc
     4441 ctgtaccggc tcatggtcgc gatgcagtcc gagcggacgc tgaccgccgc acgctgggcc
     4501 ggcaccgggg tgcccgagga cctgatgcgg gaacggcgcg cggccaccga ccaggccgcg
     4561 accgccttcc gccgttcctg ggagcccggg accgcggtgt ccgaggtggc ggaccggcgg
     4621 ctgctggagg tcgccgaggg cctgggcgaa ctggacgcct accgcgagcg caccgacagc
     4681 gggtccggga acgccgacag cacgctcgtg ttctacaccg gcgtgatcgg ccagatgatc
     4741 cgcttctacc aggacgaact gagccacacc gaggacggcg ggctcatcga ggacacccgc
     4801 gtggtcagcg ccatgttcgc cgcctccgag atggtcgccc aggaggacat gatcatcgcg
     4861 caggccggcc cctccaggac gctgaccccc tccaggttcg ccgacctcgt caacgccgtc
     4921 ggggcgcagc ggtacctgta cgacacatgg gtcgtgccgt acctgccgga cgcgcagaac
     4981 gacctctacg cgcagatggt cagatcgggg gcgtggcaga ccaagacgcg catcgagagc
     5041 gcggtcctgt ccgagcagac gatcaccgac gacggggtga agctgccgcg ggacgtcaac
     5101 ggctggcggg ccgcgcagca gcagtggggg ccgcagctga ccaccctgaa cgccgaccgg
     5161 tcgcaggccc tgctggaccg cgccgacgcc cgggcgaccg acctcgagac ggacgtcgcg
     5221 tggctgatcg ccgggagcat cgccgcactg ctggccgtcg ccgccgtcgt cgccctcacc
     5281 acggggtcgg tgctgcgccg gctgagccgg ctgcaccacc ggacggtgac catcgccgag
     5341 cgcgtcctgc cggacgtcgt cgaccggctg cagagcggca ggcccgtcga caccgccgca
     5401 ctgcccacgg tccggggcga gaaggacgaa gtggggcgag tcaacgacgc gttcgcccgg
     5461 gtggtcgccg tgtcggtgga cggccacaca cagctcgcgg ccgagcggca gggcttcggc
     5521 atgttcgccg cgggcatcgc ctcacggacc gggaacctgg tcagccgtca gctgagcctc
     5581 accgaggagc tccaggacgc cttcggccac gacgaggcgc tcctggccca gctgatgcgg
     5641 gccgaccagc tcacggtcgg catgcgccgg cagatcgaga acctgctcat cctctcgggc
     5701 ggcgagatcc ccgaccccca taccgaaccc atgcgcatcg ccgacctgct gcgcgaagcg
     5761 gccgcggagg tcgaggactt ccggcggatc gagcgccagg cgctggacga gatcagtatc
     5821 gaggccgccg tgatcagcca ggtcagccac ctgctggcgg agctgctgga caacgccacg
     5881 cggttctcgc cgccgaggtc caaggtcgtc atccgggccg agctggtggc cgacggaatg
     5941 tcggtcgaga tcgaggaccg cggtccgcgg gtggcccccg cgacctacga ggagatgaac
     6001 gggcgcctgc actcggcacc gccgtacgcg gtcctggcgg agaacgccca ccggctgggt
     6061 ctcttcgtgg tcggccacct cgccgacggg ctcggcgcca cggtcacgct gcgcagatcg
     6121 gtgtacggcg ggacgtcggc cgtggtgatc ctcccccggg aactgctcgt accgacccgg
     6181 aacgagacgg gtggcgcgcc ggacgcgccg gttcgtgggg agtccccggc ggacgcgccg
     6241 gttcgcgggg agttcccggc ggacgccgtc catgagctgc cgccgagtgc ggaggacgcc
     6301 ggggtgcggt ccgtacgcgc ggagcccgcg ctcgcgacgg acggccgcgg cgagggcgag
     6361 gtcggggccg aacctgtccg gcgcacggat gccggtctcc ccgtccgcgg gtcccacggg
     6421 cggacgcccg ggcgtccgga cggggagtcg cctggccggt ccgccggtga gccgcccgag
     6481 ccggacgggg agccgaccgc actggacgcg gtctcgccgg gcaggccgta cgggctggtg
     6541 ccgaggcagc cgggagggaa gtcgccgggc cggccccgcg cggcgctgcc cgagcgcgcg
     6601 gccaagccgt ccggcgaccg gaccgccgag ccgccgcacc ggcggccgcc cccgcccccg
     6661 ccctcggctc ggcccgtccg ccccgtcggg cccgcccgtg acgtgcgtcc ggccctcccc
     6721 gagcgggtcc cgcagacgca catggccgag cagctcctgg ggccgcgccg cgcgaccgag
     6781 gcggcggcag tgcgggaagc ggacaccccc gaagaggtgg ccgacgcctg ggcggactac
     6841 gagcagggaa cccagacggt ggaagacgag ctccgacagg atcagcgatg acgacgacat
     6901 ccaacgacat gatctacagc gtcctggaca acaacctcag caggatcgcg gacatcaagg
     6961 gcgccgttct gctgtccaat gacgggatca tgctcagctc ctacctgctg gaccgccccc
     7021 agggggagcg catcgccgcg gcgtcctccg ggatcgcgtc cacgatgaag gcgatctccg
     7081 gggatgtcga cggcggccgg gtgatccgcc agctggtcga gatggaggac cggtacctct
     7141 gcatcgtcgg atgcggggag ggcagcaccc tcatcgtcgt gacgtcccgc aaggcccggc
     7201 tcggcgaact gggcggcgag gccgtacgca cggcgcaggc gctcggggaa tggctgagca
     7261 cacccggacg cggtcaggcg ccgacgtcgt aatgaccgaa gcgtcgcgcc gcgcaggcgg
     7321 tcgccggacg cgcctgtacg ccctgaccga cgggcgtacg accgctccgc ccgtctcgct
     7381 gaccatggac acgacggtca cggcagcggt ctccgcggac gcctacgacg gcctgcccag
     7441 cgagtggcag gccgtcctgt ccctgtgcgt gccgccgaac ggcctggcgg tcgcggagat
     7501 cgccgcccgt atgcacatgc gcctgacgcc cacgatcctc ctcctcggcg agctggagga
     7561 ccgtgggctg gtccggcacc ggtcgcccct ggaggagacc gagaccacca atgtcaacct
     7621 gctcatgaga atcagggaca accttgcccg gatatgacac ctctgcccag gaagtggccc
     7681 ccgtcaagat cctcgtggcc gggggattcg gcgtcggcaa gacgactctg gtcgagacga
     7741 tctccgagat cgagcccctg cgcacggagg agcggctgac ggccgccggc gtcggcgtcg
     7801 acgacctgcg ggggatcgag tccaagtcgt tgaccaccgt ggccatggac ttcggccgca
     7861 tcaccctcac cgacgccggt gtcgtcctct acctgttcgg gacgccgggc caggagcgct
     7921 tctggttcat gtgggacgac ctgctcgacg gcgccctggg agcgatcgtg ctggtcgaca
     7981 cccgccggct cgaccgcagt ttccccgcgg tggacttctt cgagagccgg gggctcccgt
     8041 tcgtggtcgg cgccaactgc ttccacggcg aacagctcta cagccccgag gagatcaggt
     8101 cggccctgca cctccgcgac ccggacacac ccgtcctgat gctcgacgcc cgcatgcgcg
     8161 cggacgtacg cgcggcgctg ctcgccctcc tcgacatgct gatcgccaag gccgggacgg
     8221 tggcccgggt ctgacggcgg atcgccgggc ctcgccaccg ggggagtccg gcggcggccc
     8281 cgcctacggg aaaccggcac ccggggcctg acgcacggcc gagtgcggca cgcccggcgc
     8341 cgcggttcct gccccggccc gggcccccgg cggcaggcag agcgcggcgc ggccaccgcg
     8401 gcgcgttgcc ccaccccgaa gcgggccctg gccatgctgc cgtcctcatg gggatgccgc
     8461 tctcggccgt cgcggtgctc ggcgtcgcgc atgcgctgat caaccgtgtc gggcctgcgc
     8521 tccaggtgcc cggctgcgcc gccgctccgg gagcctgatc gcgcccgccg cgctgcactg
     8581 cgcgctcaac agcgccggtt gcgcgccggc gtggcaggtc acccggcctg gctgacgggc
     8641 cgtcagaagc ggaggcgggg gcgccgcccg cgccggggcc ggcagacccc ggacgagcgg
     8701 cgcccacgcg ccctcaggcc cccggcggca cgtgtgccgg gcggccgccg ccgcgggtga
     8761 gccgatggcc ccagattccg gccagcgcgg cgagcaccgc tccgcacgcc gtccagagga
     8821 tgcgcgagga ccaccagccc gacgcccagc cgccgtccgg ctcgacgtcc cggcccgagg
     8881 cggggaccag cggggcggcg agccggccgt ccacggccgt ggcgccgccg gaatccgccg
     8941 tgacgacctc caccgcggcc tcggccggtt cgcccaggtc ctcggcgggc gccgtgacga
     9001 cggtcagccg tacgtagtac gccccgggca gcgggtcgtt cgcccagggc tcggaccagg
     9061 cccggaccgt ccgcagcgcg cagctcagct cgaccgacga cgcccccgcc gggacggccc
     9121 gggtgtcgct gccgtagcgg caggcctggc ggcgccgcag cccgtcgtac acgtcgagcc
     9181 gccatgtccg ggtgccgcgg cccgccgtgg agcggggcag ttccaccgtg gcccggacgg
     9241 tggcccgctg cccggcgtcg gccgggaact gccagtacag atagtcaccg gtggacgcct
     9301 gcgcggtggc ccgctgcccg gggcggatca cggttgccgt gcggaacgac gttccggcct
     9361 cggtcggcgc ggcgccctcg tcccccgtgc tcgcactcgg cgacggcgag tcgacggcgg
     9421 cgacgcccgg gaacggcagc gtgaacagcg cggctgcggc gagcagtccg gccgtgagaa
     9481 ctcgtacggt acgcatcagt tgctcctcca gacggcgatg cgccagcgag agatccagcc
     9541 ccacagcgcc cccgccgcga agccggcgag cgtcagcagg ccgagcagcc accagccgtg
     9601 gccgaggccg aggaacgccg cgtcgccggc gtcccggggg ccgccggtga tgtcgatggt
     9661 cagctcgagg ggcaggccgg gggacgtccg gaccgacgcg ggggcggaga aggagttgct
     9721 cacccgcagg cagacggtct cggcggcggg tccggagtcg ccggcgtcac cggagtcgcc
     9781 ggcgtcaccg gagtcgccgg tgtccgcctt ggggtagcgg aggcccgtgg agacgacgtc
     9841 ggtgcgcccg tcacccgtgg actccccgcg cacgatctcg cggcccgcca gggtcgaggc
     9901 gcgcagcagc acaccgtggt cgcggttcac ggggcggtcg acggagatgc tgaccgaggc
     9961 gcgcagctcc tggccgggga gcaggtccac ccggtaccag cggtgctggc cgaaggcctc
    10021 gcggtcggcg tacagaccgg ccttcagccg cggcgcgtcc gcacagcggt cgccgccctg
    10081 ggtggccacc ggggtgacga cgggctccgc ggcgcggtcc accagctggc ccacccgctc
    10141 ggacagttcc tccttgtgct gaacggagga gtaggtgccg cccgtggcct cggcgatgca
    10201 catcagctgg gcgcgcatcc tggcgttggg gacgaggccg agggtgtcga tggtgatgcc
    10261 gacgcccttg gcggcgatct cgcgcgccac ctcgcacggg tcgagcgggg cgcaggtgtc
    10321 ctcgccgtcc gtgatgagca cgatccgccg ggtggcgtcg ccgccctcca gatcgtcggc
    10381 ggcgccgagc agggcggggc cgatcggggt ccagccggtc gggacgagcg tcgccacggc
    10441 cgccttcgcc tcggtccggt ccagttcgcc cactgggtag agctgccggg tgtccttgca
    10501 gccctccttg cggtccttgc ccgggtagtc ggcgccgagg gtgcggatgc cgagccgtac
    10561 gtcctccgcc accgcgtcca gcacctcgtt gaacgcctgc ttggccgcgg acatccggga
    10621 ctgcccgtcg atgtcgcggg cccgcatcga accgctgacg tcgaggacga gttcgacctt
    10681 ggggggttcc ttagcggcgg cccggtcggc cgtgccgccg gagtcggcgg aggcggcgga
    10741 ggggaggagt ccgccggtga gggtgaccag caacgcgccg cccaggacgg ccgccagtcg
    10801 ctttcgtatg atcatcggcg gatcatagtg agcgggtccg gtccggccca attcggctcc
    10861 tgggcgcggc ccgggcaact gcggtgacat gaacgccggt tggcggtggc ttccggccgc
    10921 cgccggccca acggccctgc ccgacggccc tgcccacggc ccgacctgtc ccgggcgggc
    10981 tcgcggaacc ggcggacgcg tcgcccctat gatgggccga tggcgtcgat ccggcagttc
    11041 caagtcacct tcgactgcgc gaatcccgag cgcgtcgccc gcttctggtg cgaggtgctg
    11101 gggtacgtcg taccaccgcc accgaagggc ttcgccgact gggacgagtt cgaccgcacc
    11161 ctgccgccgg agcgccgggg ttgctggttc gcatgcgtcg atccctcggg cgtgggcccc
    11221 cggctgttct tccagcgcgt cccggaaggg aagaccgtca agaaccggct gcatctggat
    11281 gtgcgggtcg gcaccgggct tgtcggtgag gagcgcctgg ccgtgctcga ggccgaatgc
    11341 gcacgactgg tcgcgctcgg cgcggtacgg gtgcgactgc tgcgcgccga cggcgtcaac
    11401 gagtcgtgcc tcgtgatgca ggacgtcgag ggcaacgagt tctgtctcga ctgagtggcc
    11461 gcgagcgcgg cgcctgcgcg aggcgaccgg gcccgcgccg gtcgccgggc tgtcggcggc
    11521 ggcccggccg ccgggccgcc gccggaccgt cccgggcgtc gcgccctcac atcaactgcc
    11581 gccgcaccaa ctcgtgcagc cgtccgccca cctcggccag cagccgggcg ggcgggccct
    11641 gctgcaccac ccggccctcg gacatgacga tcacgcggtc ggcgtccatc accgtggaca
    11701 gccggtgcgc gatgacgacc cgggtggcgc gcagcgcccg cgtgctctcg gtgacgatcc
    11761 gctgggtcgc gttgtccagg gcgctggtcg cctcgtcgaa gaacagcacc cgcggacggc
    11821 gcaccagggc ctgggcgatc atcagccgct gccgctgacc gccggagatc gcgccgctgc
    11881 cggagatcat ggtctgcatg cccatgggca tccggcggat gtcctccgcg agccccgcca
    11941 tctcggccgc cgcccaggcc tcttcctcgg tgaacggctc cgcgccccgg atgcagtcca
    12001 ggatcgagcc ggtgaacggc tgggagttct gcaggacgac accgcactgg cggcggaccg
    12061 ccgcctggtc cagggcggcg aggtcctggc cgtcgtacag cacgctgccg gaggcgggac
    12121 ggtcgaagcc gatgagcatg cgcagcaggg tcgacttccc gcagccgctg ggcccgacga
    12181 tcgcgacgaa ctccccgggc tctacgctca aggacacgcc gtcgaggacg aggggcccgt
    12241 cgtcggtgta gcggaaggac accttgcggg tctcgatcgc acccgacagc ccgcccggct
    12301 gggtgctggt gccccgtacc tccggagcct cgtccagtac cggcttgacc tgctcgaaca
    12361 tgggcagtac ggcggcggcc gagaccagcg cgccggtcag ctgggtcacg gacgtcagca
    12421 tcatcgtgac ggccgtgtgg aacgtcagga actcgcccgc cgtcaggctg ccgctcgccg
    12481 ggcccgccag cagcatgaac atgatcagcg cgctcagcgg cagatagacc gcgtccagaa
    12541 cggtcgtcag attgcggatc cggccggccc gccggtgcag ctcccggctg cgcgcgaact
    12601 gcttcgccca ggccgcgtac gcgaagctct ccgccgccgc gacccgcagc ttgggcagtc
    12661 cccgcagggt ctggaaggcc tggttgttca gcttgttgtt cagttcgacc agccggcgct
    12721 gccagcgcag ctgccacagc cccatgccga ggaacaccgt gccgatcacc agcagcatgc
    12781 cgatcgccgc cagcgccagc ggcacgctgt agacgagcag cagcaccatg ttcatcgcgc
    12841 cgaccgtgct cgcctggacg acgaccggcc ccacccccga cagcagccgc cggatggcgc
    12901 tgatgcccat ggccgcgctc gccagctcac cggtggagcg ctccgcgaag aacttcgtcg
    12961 gcagccgcag caaccggtcc cacaccgcgg gctgcagcgt gctctcgatg cgtccctcca
    13021 ggcgcagcac ggtgaggttc tgcatcagca tgaacacggc cgacacgccg cccgcgacca
    13081 tcacggccac cgacacctgg acgatcaggt cggttcgggc gccgggcacg tactccccga
    13141 gcaccttgcc ggtggcgacg ggcaccacgg cgccgaggag gaccgcgacc agtcccgcga
    13201 cggccaggtt ccgcacgtcc gtgcgcgagc cgcgcaggct gaagaccatc agccgccaca
    13261 ggctcatcgg ccgctcgggc agcggccggt agaacatcac ggcccgcggc tcgaactcct
    13321 cggcgttctc ctcgtccacg cggatacggc tgccggtggc cgggttcacc gcccggtacc
    13381 cgccgcgccg ccacagcagc gcgaccggcg ccccggactt ggcccggtgg cccaccagcg
    13441 ggccgcagtc ctcccgccac cagcggccgt cgagccggac ggcccgggtg cgcacccggg
    13501 aggccagcgc gatccgctcc accgggccgg tccgctcgtc gaccggtccg ccccggggcg
    13561 gttcggtgag cgtgataccg gccgtcgagg cgacgagccg gcacaccgcg taggcggcgt
    13621 cgtcggacac ggcgttccgg gagcgcgccg aggaggcccc gcgggagcgg ccgatggacg
    13681 ccagcagcgc ctggtcggca ccggcgcgca ccgcttcgcc ggccttgatc cccgccgccg
    13741 cccggtcctc gtgggcctgc tccatgcgct cgatccagcg gtcgagcccc gacagcagcc
    13801 ggtactgctg gttgaccatc tgctgccaca gggcgccgtc gacgagcaga ccggcggcgg
    13861 cctcggcgct gaacgcggcg ccgtactgca cactgccggg gaacaccggc agccacagga
    13921 cgtcgtcgtc ggtcaccgcg tcgtcgtccg ccgtccgccc gtccagcggc gcctcgaaca
    13981 gcacccgctg accgcgcccg acgccgagcg cgaacgcgtg ctccagcagg ctgagagtgc
    14041 cgtcctggct gtcgtacccg ctctggtagg ggctctggta cgaccaggcg tcgccgtacc
    14101 ctgactgcgg ccggagctcc agcagcggga tgcggcgcag tacgcatccc tgcagcgggc
    14161 ggccgaccag ggtgtgctgg gggccctcca ccgggccgag gagcagtgtg ccctgctcca
    14221 gtcgcccgag gaagtgccat tgcccctgcc gggccgcgtc gaccgcgaac aggtcgagcg
    14281 cgccgtcgac cagcagccac agcacctgcg ggccctccag cggcagactg cgcagcccgg
    14341 cgcagtcgac gtgctgcccg agaccgccga acgcggcgag caccgcgtcg tcgggacgcg
    14401 cggacccggc gtggtgaccg ggctgtacgg ggatcacgtc agtgctcctt gaccagttcg
    14461 gcgtacgcgc ccccgcgcgc gagcagttcc tcgtgccggc cgcgctccac gaccgtgccg
    14521 tggtcgagga ccacgatctc gtcgctgtcg cggacggtgc tcagccggtg cgcgatcacc
    14581 acgcaggcgc agccgcggcg gcgcagattg tcgatgatca gctgctcggt ctcggcgtcc
    14641 agcgcactgg tcacctcgtc cagcaccagc acactggggc ggcgcaccag tgcccgggcg
    14701 atctccagcc gctgccgctg cccaccggag aagttgcggc cgtcctgctc gacccggccg
    14761 tggacgccgc cgggccgccg ggcgaccacg tcgtacaact cggcgtccct cagcgcgtcg
    14821 gcgacggcct cgtcggtgat cgaggggtcc cacagggcca cgttgtcgcg taccgtcccc
    14881 tcgaacagga acacctcctg gtcgacgaag gagacggagg cggcgagcgc gccgcgcggg
    14941 atctcgtcca gccgccgtcc gtcgatgcgg atgacgccct cccacgggct gtagaggccc
    15001 gcgatgagcc gggacacggt cgacttgccg ctgccggagc cgccgacgag cgcgacctgg
    15061 ctgcccggcc ccaccgacag cgagaagccg gtgagcagcg gcttgtccag cgggctgtat
    15121 ccgaaggcga tgttctccag cgtgacgtgc ccgcgcagcc tgcgggtgct cgcggggggt
    15181 tcggggcggg tgtacagccc gtcggcgggg aagttctcca cgtccttcag ccgggccacg
    15241 tcggcggcga agtcctggat gcgggacgcc atcccgttga ggcgggtgat cggcgcggtg
    15301 aaccgtgtca ccagggcctg gaaggccacc agcagaccga tggagatatg gccctcgacc
    15361 gcccgcatcc cgccgatcca caggatgagc ccgctgttca gcgtggccag ggcgggcgcc
    15421 acgacggcga gcgcggcgct cggcacaccg agccgctgct gctcctccag ggtgatggcg
    15481 tgctgcccgg cccagcggcg gaagtagccg ttctcgccgc cggtcgcctt catcgtctcg
    15541 atgagctgga tgccggtgta cgaggtgttg gtcagccggg cgctgtccgc gcgcagcttc
    15601 tgggtgcggg tcgcccgcag acgtaccacg atccgcatgg cgaccacgtt gagcagcgcg
    15661 atgagcaccc cgacgacggt gagctggggg tcgtaggtcc acagcagcag cgcgtagagg
    15721 aggacgacga cgccgtcgac ggcgaaggcg gtgagatcgc gggcgagggt ctcggcgacc
    15781 gcgtcgttcg actgcagccg ctggacgagg tcggcgggac tgcgctggcc gaagaacgtc
    15841 acgggcagtc tgagcaggtg ccggaagaac cgggcgctgc tcagcgtgga ggagatgacg
    15901 cggccgcgca gcaggttcgc ctgctgcagg ccggtcagca cggcggtcag tgcgaccatc
    15961 gccgccatcg aggcgaacag cacacccagc agcgaggtct gacggcccac caggtacatg
    16021 tcgatatagg tgcggctcag cgcgggcagc gccgcgccga ccgcgaccag cagcaggctg
    16081 gcgaccagcg cggcgagcat ggtgccggtg gttccgcgca gccgggcggg caccgagcgc
    16141 agcacgcccg gcctgcggcc gcctcgtcgg aagccgtcac cgggctcgaa gaccagcacc
    16201 accccggtga agctggtgtc gaagtcctcc atggacacga accggcggcc cttgtcgggg
    16261 tcgttgatgt gcaccccgcg gcggccgaga cggcggccca tgccgtcgtg gacgacgtag
    16321 tggttgaact cccagaacag gatggcgggc ggccggaccc cggcgagcgc cgccggttcc
    16381 atctgcatgc ccttggcctg gaggccgtaa ccgcgggccg ccttgaggat gttgctggca
    16441 cgggagccgt cgcgggagac accgcaggcg atccgcagct cctccagggg cacgtgccgg
    16501 ccgtagtggg cgagcaccat ggcgagtgcg gcggcaccgc actccacggc ctccatctgg
    16561 agcacggtgg gggtgcggac gctcttccgc ctcgcgggcg cggcgggctt gcgggcgcgg
    16621 cgcgggttcg cccgccgctg atcgccgccg cgccgtccgc ccgcggtacg ggcggtggtt
    16681 cgggcggtgg tacggccggt gctacggccg gtgctacggg gagtggtgct accggaagtg
    16741 gtgctaccgg gagtggggga gggagccgtc ac
//
